Multiple myeloma and malignant plasma cell neoplasms

CD2_MULTIPLE_MYELOMA_PLASMA_CELL_EXALLC

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

None

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C90
  • Hospital discharge: ICD-9 203
  • Hospital discharge: ICD-8 203
  • Cause of death: ICD-10 C90
  • Cause of death: ICD-9 203
  • Cause of death: ICD-8 203

2 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF8
Parent code in ICD-10
C81-C96
Name in latin
Myeloma multiplex et neoplasmata maligna plasmacytorum

Similar endpoints

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 1646 722 924
Unadjusted period prevalence (%) 0.34 0.25 0.41
Median age at first event (years) 69.18 68.21 69.95

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1545
Matched controls
15450
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
9732/3-C42.1
ICD-O-3
Plasma cell myeloma of bone marrow
+∞
323.0
784
*
153
Kela drug reimbursment
Lenalidomid
4574.5
323.0
607
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
437.4
323.0
1074
80
C90.0
ICD-10 Finland
Multiple myeloma
4503599627370496.0
323.0
1384
*
L03AA02
ATC
filgrastim; parenteral
1259.4
323.0
449
5
329
Kela drug reimbursment
Lenalidomide
2655.6
323.0
378
*
XW000
NOMESCO Finland
Bone marrow biopsy
76.3
323.0
737
182
A04AA01
ATC
ondansetron; systemic, rectal
63.3
323.0
489
112
H02AB02
ATC
dexamethasone; systemic
337.4
323.0
852
56
L04AX04
ATC
lenalidomide; oral
4014.0
323.0
559
*
NJ3DA
NOMESCO Finland
Long bones of extremities X-ray examination
344.8
310.9
305
11
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
18.5
288.0
470
356
M04AA01
ATC
allopurinol; systemic
9.1
286.8
735
1404
WW300
NOMESCO Finland
Transfer of autologic stem cells
1631.9
286.5
270
*
N02AA05
ATC
oxycodone; systemic
9.2
251.9
613
1032
ZX112
NOMESCO Finland
Subcutaneous
98.7
246.9
269
33
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
2504.7
241.0
227
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
+∞
237.8
222
*
J05AB01
ATC
aciclovir; systemic
7.0
235.1
730
1742
AA1AA
NOMESCO Finland
Head X-ray examination
66.5
234.5
270
49
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
64.7
228.3
264
49
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
5.7
218.5
931
3229
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
31.6
216.8
292
113
L01AA03
ATC
melphalan; systemic
1112.5
203.9
195
*
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
449.5
202.1
198
5
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
30.6
200.3
272
107
ZX120
NOMESCO Finland
Intravenous
10.1
191.3
417
546
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
508.4
185.3
181
*
WX2DD
NOMESCO Finland
Low-dose CT of skeleton in whole body
658.5
181.5
176
*
WW500
NOMESCO Finland
Blood transfusion
22.0
180.5
271
148
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
178.6
168
*
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
63.5
154.9
180
32
R50.9
ICD-10 Finland
Fever, unspecified
6.2
150.2
466
1000
A49.9
ICD-10 Finland
Bacterial infection, unspecified
6.6
146.3
429
852
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
377.5
140.2
139
*
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
374.5
139.1
138
*
J05AB11
ATC
valaciclovir; oral
5.9
137.8
443
981
JN4AD
NOMESCO Finland
Body CT examination
12.9
136.4
253
230
C90.2
ICD-10 Finland
Extramedullary plasmacytoma
+∞
135.4
128
*
B03XA02
ATC
darbepoetin alfa; parenteral
23.0
134.6
198
98
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
10.3
132.7
278
322
M05BA02
ATC
clodronic acid; systemic
700.7
132.6
129
*
393
Kela drug reimbursment
Pomalidomide
+∞
131.1
124
*
YNB10
NOMESCO Finland
Collection of stem cells for transplant
+∞
131.1
124
*
WD115
NOMESCO Finland
Multiple cystostatic therapy of methastized malignancy
1333.5
128.0
123
*
WD515
NOMESCO Finland
Demanding therapy of malignancy with enzyme inhibitors and similar treatments
1286.4
123.7
119
*
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
12.7
122.7
229
209
1507
Kela drug reimbursment
Pomalidomide
+∞
118.2
112
*
WW409
NOMESCO Finland
Other aferesis
1216.4
117.3
113
*
1XX32
NOMESCO Finland
NA
1204.7
116.2
112
*
B01AB05
ATC
enoxaparin; parenteral
3.7
114.9
697
2809
NE1AA
NOMESCO Finland
Pelvis X-ray examination
6.8
114.6
319
572
L04AX06
ATC
pomalidomide; oral
+∞
111.8
106
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
5.6
110.4
361
792
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
3.8
109.8
602
2211
A03FA01
ATC
metoclopramide; systemic, rectal
5.2
106.7
381
921
JN4BD
NOMESCO Finland
Extensive body CT
8.2
106.6
255
363
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.3
106.6
930
4860
WW402
NOMESCO Finland
Leucoferesis
+∞
106.5
101
*
WF004
NOMESCO Finland
Palliative radiotherapy
1089.4
105.6
102
*
ZX108
NOMESCO Finland
Inhalation
65.5
104.7
121
20
XX3DW
NOMESCO Finland
Time consuming IT work
9.2
101.1
224
280
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
11.9
99.8
191
181
M90.7*C90.0
ICD-10 Finland
Pathological fracture in multiple myeloma
+∞
99.0
94
*
Z51.5
ICD-10 Finland
Palliative care
13.6
98.1
176
145
L03AA13
ATC
pegfilgrastim; parenteral
+∞
95.8
91
*
C91.1
ICD-10 Finland
Chronic lymphocytic leukaemia of B-cell type
+∞
94.8
90
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
336.3
94.0
94
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
91.6
87
*
WW200
NOMESCO Finland
Immunization
14.3
90.4
158
122
L04AX02
ATC
thalidomide; oral
908.1
88.6
86
*
ZX090
NOMESCO Finland
Other technic of radiotherapy
452.0
87.0
86
*
C44.31
ICD-10 Finland
Basocellular carcinoma of the skin on another or unspecified part of the face
73.7
85.4
97
14
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
874.5
85.4
83
*
WF002
NOMESCO Finland
Radical radiotherapy
155.3
83.9
88
6
A04AA02
ATC
granisetron; systemic, transdermal
297.0
83.5
84
*
J01MA12
ATC
levofloxacin; systemic
3.5
82.7
471
1707
B03XA01
ATC
erythropoietin; parenteral
31.0
82.1
110
38
212
Kela drug reimbursment
Gout
11.3
81.0
158
154
398
Kela drug reimbursment
Ixazomib
+∞
80.9
77
*
D64.9
ICD-10 Finland
Anaemia, unspecified
4.3
79.7
335
930
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
78.8
75
*
B01AB10
ATC
tinzaparin; parenteral
7.6
77.1
191
281
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
+∞
76.7
73
*
A02BC02
ATC
pantoprazole; systemic
2.8
76.2
1124
7473
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
774.6
75.9
74
*
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.9
75.7
617
2853
1505
Kela drug reimbursment
Ixazomib
+∞
75.6
72
*
WD135
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
+∞
74.6
71
*
L01AA01
ATC
cyclophosphamide; systemic
69.0
74.2
85
13
130
Kela drug reimbursment
Malignant tumour
+∞
71.4
68
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.0
69.2
316
935
5BA08
NOMESCO Finland
NA
60.1
68.4
80
14
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
9.0
67.5
149
181
115
Kela drug reimbursment
Breast cancer
+∞
67.2
64
*
C90.1
ICD-10 Finland
Plasma cell leukaemia
+∞
67.2
64
*
M05BX04
ATC
denosumab; parenteral
7.0
66.1
172
270
YX9AD
NOMESCO Finland
Other CT eamination for dose design of radiotherapy
330.1
63.9
64
*
TPH04
NOMESCO Finland
Cathetrisation of vein
3.0
61.0
436
1798
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
4.8
60.9
221
519
116
Kela drug reimbursment
Prostate cancer
+∞
60.8
58
*
B74
ICPC
Malignant neoplasm blood other
215.0
60.5
62
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.1
60.0
398
1559
M49.5*C90.0
ICD-10 Finland
Vertebral fracture due to multiple myeloma
+∞
58.7
56
*
J01MA14
ATC
moxifloxacin; systemic
4.2
58.1
242
651
Z52.89
ICD-10 Finland
Donor of other organ or tissue
567.6
55.9
55
*
NA7DG
NOMESCO Finland
Spine and spinal cord very extensive MRI examination with high intensity magnet
23.4
54.1
78
35
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
+∞
52.4
50
*
ZX080
NOMESCO Finland
Image guided radiotherapy
+∞
52.4
50
*
GA5AA
NOMESCO Finland
Rib X-ray examination
66.8
50.5
58
9
C03CA01
ATC
furosemide; systemic
2.3
50.4
691
4013
WF003
NOMESCO Finland
Adjuvant radiotherapy
263.6
50.4
51
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
6.0
50.2
146
264
TK800
NOMESCO Finland
Hemodialysis
8.7
49.4
110
135
9823/3-C42.1
ICD-O-3
B-cell chronic lymphocytic leukemia/small lymphocytic lymphoma of bone marrow
+∞
49.2
47
*
PJA12
NOMESCO Finland
Sentinel node biopsy
252.7
48.3
49
*
JN6DR
NOMESCO Finland
PET-CT of whole body metabolism
35.8
48.2
62
18
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
247.4
47.3
48
*
C91.0
ICD-10 Finland
Acute lymphoblastic leukaemia [ALL]
+∞
47.1
45
*
YL1BD
NOMESCO Finland
Extensive CT examination of pelvis for dose design of radiotherapy
+∞
46.1
44
*
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
7.7
45.0
108
149
C50.41
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, ductal tumor
+∞
45.0
43
*
L01XX50
ATC
[U] ixazomib; oral
+∞
45.0
43
*
C90
ICD-10 Finland
Multiple myeloma and malignant plasma cell neoplasms
+∞
45.0
43
*
YN7BD
NOMESCO Finland
Extensive CT examination of spine for dose design of radiotherapy
+∞
45.0
43
*
NK6CT
NOMESCO Finland
Bone biopsy with CT guidance
157.8
44.0
46
*
JN4CD
NOMESCO Finland
Very extensive body CT
11.8
43.2
81
72
ZX070
NOMESCO Finland
Intensity modified radiotherapy
226.1
43.1
44
*
8500/3-C50.9
ICD-O-3
Infiltrating duct carcinoma, NOS, of breast, NOS
+∞
42.9
41
*
A41.9
ICD-10 Finland
Sepsis, unspecified
5.7
42.2
126
235
A79
ICPC
Malignancy NOS
220.9
42.1
43
*
YN7AD
NOMESCO Finland
CT examination of spine for dose design of radiotherapy
+∞
41.8
40
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
11.0
41.8
81
77
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
4.5
41.5
156
375
WZC30
NOMESCO Finland
Teaching
3.4
41.5
218
704
WD505
NOMESCO Finland
Simple enzyme inhibitor or similar therapy of methastized malignancy
418.1
41.3
41
*
N17.9
ICD-10 Finland
Acute renal failure, unspecified
4.8
41.1
146
331
1CX01
NOMESCO Finland
NA
113.1
40.9
44
*
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
+∞
40.8
39
*
NB6AA
NOMESCO Finland
Humerus X-ray examination
8.4
40.3
91
114
M87.1
ICD-10 Finland
Osteonecrosis due to drugs
77.3
40.1
45
6
127
Kela drug reimbursment
Transplant complication
14.1
40.0
69
51
M84.4
ICD-10 Finland
Pathological fracture, not elsewhere classified
110.5
39.9
43
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
+∞
39.7
38
*
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.1
39.4
630
3794
D48.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Bone and articular cartilage
14.9
39.3
66
46
N08.1*C90.0
ICD-10 Finland
Glomerular disorders in multiple myeloma
+∞
38.7
37
*
8090/3-C44.3
ICD-O-3
Basal cell carcinoma, NOS, of skin of other and unspecified parts of face
+∞
37.6
36
*
D70.89
ICD-10 Finland
Neutropenic splenomegaly
21.1
37.2
55
27
E83.50
ICD-10 Finland
Hypercalcemia
12.7
37.2
67
55
YL1AD
NOMESCO Finland
CT examination of pelvis for dose design of radiotherapy
+∞
36.6
35
*
H02AB06
ATC
prednisolone; systemic
2.0
36.2
776
5204
A06AD11
ATC
lactulose; oral
2.5
36.2
338
1565
N03AX16
ATC
pregabalin; oral
2.3
36.1
416
2145
L02BG04
ATC
letrozole; oral
49.0
35.8
43
9
A05AA02
ATC
ursodeoxycholic acid; oral
12.8
35.7
64
52
D70.82
ICD-10 Finland
Drug-induced neutropenia
33.0
34.5
45
14
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
5.1
33.7
110
227
NK6AN
NOMESCO Finland
Total body bone isotope imaging
49.9
32.6
39
8
L02BB03
ATC
bicalutamide; oral
+∞
32.4
31
*
E85.9
ICD-10 Finland
Amyloidosis, unspecified
55.6
32.4
38
7
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.9
32.1
723
4855
TPX10
NOMESCO Finland
Implantation of vascular injection port
7.5
32.0
77
107
WX1BG
NOMESCO Finland
Total body MRI with high intensity magnet
323.3
32.0
32
*
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.8
31.5
228
909
PJD52
NOMESCO Finland
Block dissection of axillary lymph nodes
+∞
31.3
30
*
L01XG03
ATC
ixazomib; oral
+∞
31.3
30
*
YG1AD
NOMESCO Finland
CT examination of thorax for dose design of radiotherapy
+∞
31.3
30
*
NF3AA
NOMESCO Finland
Femur X-ray examination
7.1
31.2
78
115
C44.51
ICD-10 Finland
Basocellular carcinoma of the skin on the torso
61.3
31.2
36
6
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.0
30.7
197
726
N02AX02
ATC
tramadol; systemic, rectal
1.9
30.7
686
4573
HA1AA
NOMESCO Finland
X-ray mammography
6.2
30.6
84
141
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
4.2
30.5
122
310
M90.7
ICD-10 Finland
Fracture of bone in neoplastic disease
+∞
30.3
29
*
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
13.0
30.0
53
42
HAC20
NOMESCO Finland
Total mastectomy
108.8
29.7
32
*
ZXD05
NOMESCO Finland
Urgent procedure
2.0
29.3
508
3066
WX1CG
NOMESCO Finland
Extensive total body MRI with high intensity magnet
+∞
29.2
28
*
C83.31
ICD-10 Finland
Diffuse lymphoma with large B cells
+∞
29.2
28
*
HA1AE
NOMESCO Finland
Ultrasound examination of mammary glands
7.1
28.8
72
106
L02AE02
ATC
leuprorelin; implant, parenteral
29.9
28.6
38
13
2030A
ICD-9 Finland
Multiple myeloma and immunoproliferative neoplasms, Multiple myeloma
+∞
28.2
27
*
N16.1*C90.0
ICD-10 Finland
Renal tubulo-interstitial disorders in multiple myeloma
+∞
28.2
27
*
5BA03
NOMESCO Finland
NA
+∞
28.2
27
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.2
28.0
156
520
T86.0
ICD-10 Finland
Bone-marrow transplant rejection
147.6
27.7
29
*
H02AB09
ATC
hydrocortisone; systemic
6.5
27.7
73
116
L02BA01
ATC
tamoxifen; oral
98.4
26.7
29
*
1AA01
NOMESCO Finland
NA
142.4
26.7
28
*
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
4.5
26.7
97
225
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.4
26.5
135
421
WX1DG
NOMESCO Finland
Very extensive total body MRI with high intensity magnet
+∞
26.1
25
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
+∞
26.1
25
*
166
Kela drug reimbursment
Dalteparin and tinzaparin (treatment for more than 6 months)
+∞
26.1
25
*
NBJ60
NOMESCO Finland
Internal fixation of fracture of shoulder or upper arm using intramedullary nail, humerus
61.1
26.0
30
5
E85.89
ICD-10 Finland
Other amyloidosis
73.9
25.8
29
*
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
5.5
25.3
76
143
C85.9
ICD-10 Finland
Non-Hodgkin lymphoma, unspecified
+∞
25.1
24
*
A06AH03
ATC
naloxegol; oral
26.7
24.9
34
13
YX9BD
NOMESCO Finland
Other extensive CT eamination for dose design of radiotherapy
254.0
24.7
25
*
306
Kela drug reimbursment
Erythropoietin and darbepoetin
32.6
24.7
32
10
G62.0
ICD-10 Finland
Drug-induced polyneuropathy
43.6
24.6
30
7
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
5.5
24.2
73
138
EB1BI
NOMESCO Finland
Cone beam imaging of teeth and jaws (1–2 quarters)
11.9
24.0
44
38
NB4AA
NOMESCO Finland
Scapula X-ray examination
31.6
23.7
31
10
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
3.0
23.7
147
528
L04AD01
ATC
ciclosporin; systemic
8.5
23.7
52
63
Y77
ICPC
Malignant neoplasm prostate
126.9
23.6
25
*
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
4.7
23.4
81
179
SAA03
NOMESCO Finland
Extended examination of mouth
1.8
23.1
505
3252
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.8
23.0
503
3234
A07AA02
ATC
nystatin; oral
3.1
23.0
132
449
C50.99
ICD-10 Finland
Breast, unspecified
+∞
23.0
22
*
Z51.0
ICD-10 Finland
Radiotherapy session
+∞
23.0
22
*
ZXE00
NOMESCO Finland
One hour or less
1.8
22.8
570
3830
WF099
NOMESCO Finland
Other radiotherapy
84.7
22.7
25
*
GD1AD
NOMESCO Finland
Thorax CT examination
4.1
22.6
90
228
HAB40
NOMESCO Finland
Wedge excision of mammary gland
23.3
22.6
32
14
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
4.2
22.6
87
214
N05CF01
ATC
zopiclone; oral
1.8
22.4
538
3564
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
22.3
477
3040
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.5
22.2
194
851
L03AB05
ATC
interferon alfa-2b; parenteral
35.6
22.1
28
8
L01BB05
ATC
fludarabine; systemic
+∞
21.9
21
*
M49.5*C79.5
ICD-10 Finland
Metastatic fracture of vertebra
+∞
21.9
21
*
M49.5
ICD-10 Finland
Collapsed vertebra in diseases classified elsewhere
116.6
21.6
23
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.0
21.5
318
1770
A11CC03
ATC
alfacalcidol; systemic
4.8
21.3
72
155
NEA10
NOMESCO Finland
Exploration of soft tissue of pelvis, percutaneous
50.7
21.1
25
5
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
6.3
21.0
56
91
EBA10
NOMESCO Finland
Surgical removal of tooth
2.7
20.9
147
571
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
60.9
20.9
24
*
6BA02
NOMESCO Finland
NA
60.9
20.9
24
*
8090/3-C44.5
ICD-O-3
Basal cell carcinoma, NOS, of skin of trunk
+∞
20.9
20
*
A40.3
ICD-10 Finland
Sepsis due to Streptococcus pneumoniae
9.8
20.9
42
44
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.7
20.8
152
604
EP1AE
NOMESCO Finland
Neck ultrasound examination
3.8
20.1
88
243
J10.1
ICD-10 Finland
Influenza with other respiratory manifestations, seasonal influenza virus identified
6.9
20.1
50
74
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.8
20.1
394
2422
N18.8
ICD-10 Finland
Other chronic renal failure
3.8
19.8
86
236
C91.9
ICD-10 Finland
Lymphoid leukaemia, unspecified
+∞
19.8
19
*
B73
ICPC
Leukaemia
+∞
19.8
19
*
L01BC06
ATC
capecitabine; oral
+∞
19.8
19
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
+∞
19.8
19
*
L01AA02
ATC
chlorambucil; oral
202.4
19.6
20
*
NFJ60
NOMESCO Finland
Internal fixation of fracture of other parts of femur with intramedullary nail
14.0
19.6
33
24
ZZR00
NOMESCO Finland
Flap of skin
14.0
19.6
33
24
Z3231
NOMESCO Finland
Registered nurse
1.8
19.5
419
2657
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
3.4
19.4
98
304
NA2AD
NOMESCO Finland
Thoracic spine CT examination
14.8
19.4
32
22
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
4.4
18.9
70
166
R4110
NOMESCO Finland
Physiotherapy
1.8
18.9
383
2376
HA003
NOMESCO Finland
Radiotherapy after partial ablation of mammary gland
+∞
18.8
18
*
A04AA55
ATC
palonosetron, combinations; systemic
+∞
18.8
18
*
XZZ00
NOMESCO Finland
Active surveillance of a diagnosed cancer
+∞
18.8
18
*
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
101.2
18.6
20
*
WW306
NOMESCO Finland
Transfer of stem cells from foreign registered donator
192.1
18.6
19
*
N02BE01
ATC
paracetamol; systemic, rectal
1.8
18.4
1263
11036
N17.8
ICD-10 Finland
Other acute renal failure
7.3
18.4
44
62
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
9.9
18.2
36
37
Z49.1
ICD-10 Finland
Extracorporeal dialysis
5.8
17.9
51
91
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.3
17.8
67
162
M36.1*C90.0
ICD-10 Finland
Arthropathy in multiple myeloma
+∞
17.7
17
*
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
3.0
17.6
106
373
I43.1*E85.9
ICD-10 Finland
Cardiac amyloidosis
96.1
17.6
19
*
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
9.9
17.2
34
35
3XA02
NOMESCO Finland
NA
31.8
17.0
22
7
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
12.2
16.8
30
25
L03AA14
ATC
lipegfilgrastim; parenteral
+∞
16.7
16
*
C67.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of bladder
+∞
16.7
16
*
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
+∞
16.7
16
*
M82.0*C90.0
ICD-10 Finland
Osteoporosis in multiple myelomatosis
+∞
16.7
16
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.3
16.6
158
722
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.3
16.6
165
769
9835/3-C42.1
ICD-O-3
Precursor cell lymphoblastic leukemia, NOS, of bone marrow
171.7
16.5
17
*
KCD02
NOMESCO Finland
Transurethral resection of bladder
23.3
16.4
23
10
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
12.3
16.3
29
24
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.0
16.3
244
1354
H02AB07
ATC
prednisone; oral
2.0
16.1
240
1329
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
6.8
16.1
40
60
WX110
NOMESCO Finland
Local anesthesy
1.6
15.9
880
7088
C88.0
ICD-10 Finland
Waldenström macroglobulinaemia
+∞
15.6
15
*
C50.49
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, other or undeterminated histology
+∞
15.6
15
*
8070/3-C44.9
ICD-O-3
Squamous cell carcinoma, NOS, of skin, NOS
+∞
15.6
15
*
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
5.1
15.6
49
99
SPAT1255
SPAT
Intravenous administration of medicine
2.5
15.5
125
525
A04AD12
ATC
aprepitant; systemic
161.5
15.5
16
*
C50
ICD-10 Finland
Malignant neoplasm of breast
161.5
15.5
16
*
TDM10
NOMESCO Finland
Puncture of maxillary antrum
3.7
15.2
66
183
J02AC03
ATC
voriconazole; systemic
32.0
14.8
19
6
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
32.0
14.8
19
6
C44.32
ICD-10 Finland
Spinocellular carcinoma of the skin on another or unspecified part of the face
57.2
14.8
17
*
TNE20
NOMESCO Finland
Bone marrow aspiration, pelvis
25.3
14.7
20
8
J01DB01
ATC
cefalexin; oral
1.6
14.7
1134
9795
C73.91
ICD-10 Finland
Papillary carcinoma of the thyroid gland (thyroid gland)
+∞
14.6
14
*
X76
ICPC
Malignant neoplasm breast female
+∞
14.6
14
*
ZX013
NOMESCO Finland
Radiotherapy with large shaped fields - SSD therapy
+∞
14.6
14
*
3AA13
NOMESCO Finland
NA
+∞
14.6
14
*
390
Kela drug reimbursment
Ibrutinib
+∞
14.6
14
*
WB203
NOMESCO Finland
Simple adjuvant hormone therapy of malignancy
+∞
14.6
14
*
YN1BD
NOMESCO Finland
Extensive CT examination of extremities for dose design of radiotherapy
+∞
14.6
14
*
N08.1
ICD-10 Finland
Glomerular disorders in neoplastic diseases
+∞
14.6
14
*
B02.9
ICD-10 Finland
Zoster without complication
2.6
14.6
112
458
A28
ICPC
Limited function/disability NOS
1.8
14.5
277
1671
WW302
NOMESCO Finland
Allogenic transfer of stem cells from relative
151.3
14.5
15
*
WX402
NOMESCO Finland
General anaesthesia
2.1
14.4
181
936
N19
ICD-10 Finland
Unspecified kidney failure
2.9
14.4
88
314
SPAT1088
SPAT
Blood transfusion
11.5
14.3
26
23
TPH07
NOMESCO Finland
Cathetrisation of artery
2.2
14.3
148
704
EE1AA
NOMESCO Finland
X-ray of upper jaw or palate
42.9
14.1
17
*
J13
ICD-10 Finland
Pneumonia due to Streptococcus pneumoniae
7.3
14.0
33
46
PJD41
NOMESCO Finland
Excision of cervical lymph nodes
15.9
13.9
22
14
TGC00
NOMESCO Finland
Bronchial lavation
3.8
13.9
59
161
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
3.1
13.8
78
262
ZXF99
NOMESCO Finland
Other r3eason to interrupt procedure
20.2
13.8
20
10
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.7
13.7
314
1999
J01CA04
ATC
amoxicillin; systemic
1.5
13.6
1093
9416
A41.8
ICD-10 Finland
Other specified sepsis
5.0
13.6
43
88
L71
ICPC
Malignant neoplasm musculoskeletal
75.8
13.6
15
*
XW4XT
NOMESCO Finland
Biopsy of other inner organ with radiological guidance guidance
75.8
13.6
15
*
C82.1
ICD-10 Finland
Follicular lymphoma grade II
+∞
13.6
13
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
+∞
13.6
13
*
8260/3-C73.9
ICD-O-3
Papillary adenocarcinoma, NOS, of thyroid gland
+∞
13.6
13
*
1512
Kela drug reimbursment
Ibrutinib
+∞
13.6
13
*
C44.71
ICD-10 Finland
Basocellular carcinoma of the skin of the lower extremity including the hip
+∞
13.6
13
*
KEC01
NOMESCO Finland
Percutaneous endoscopic radical prostatectomy
+∞
13.6
13
*
L01XE27
ATC
[U] ibrutinib; oral
+∞
13.6
13
*
PJ5AN
NOMESCO Finland
Localisation of sentinell lymphnode with isotope imaging
+∞
13.6
13
*
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
11.0
13.5
25
23
A40.8
ICD-10 Finland
Other streptococcal sepsis
6.9
13.5
33
49
ED1AA
NOMESCO Finland
Mandipular X-ray examination
16.4
13.5
21
13
1XC02
NOMESCO Finland
NA
12.9
13.4
23
18
N05BA06
ATC
lorazepam; systemic, sublingual
2.6
13.4
98
390
A02BC01
ATC
omeprazole; systemic
1.6
13.4
437
3061
Z2221
NOMESCO Finland
Medical doctor
1.6
13.3
374
2521
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
3.1
13.2
71
233
YA1AD
NOMESCO Finland
CT examination of head and neck for dose design of radiotherapy
40.4
13.2
16
*
JN6BD
NOMESCO Finland
Extensive CT of torso and neck
15.2
13.1
21
14
D47.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue, unspecified
22.7
12.9
18
8
ZY010
NOMESCO Finland
Hospital outpatient
3.3
12.9
65
204
B99
ICD-10 Finland
Other and unspecified infectious diseases
4.3
12.9
47
112
C44.30
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face without histology
50.4
12.8
15
*
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
4.0
12.8
50
127
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
4.3
12.7
47
113
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
4.6
12.7
43
95
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
15.6
12.6
20
13
JN6AD
NOMESCO Finland
CT of torso and neck
15.6
12.6
20
13
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.1
12.6
147
735
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.8
12.6
239
1432
C50.21
ICD-10 Finland
Malignant tumor of the upper inner quadrant of the mammary gland,ductal tumor
+∞
12.5
12
*
C83.9
ICD-10 Finland
Non-follicular (diffuse) lymphoma, unspecified
+∞
12.5
12
*
C20.91
ICD-10 Finland
Malignant tumor of the rectum invasive carcinoma
+∞
12.5
12
*
NB4DA
NOMESCO Finland
Bilateral scapula X-ray examination
+∞
12.5
12
*
8312/3-C64.9
ICD-O-3
Renal cell carcinoma, NOS, of kidney, NOS
+∞
12.5
12
*
J12.1
ICD-10 Finland
Respiratory syncytial virus pneumonia
10.1
12.5
24
24
Y84.8
ICD-10 Finland
Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
9.4
12.5
25
27
J21.0
ICD-10 Finland
Acute bronchiolitis due to respiratory syncytial virus
24.5
12.5
17
7
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
12.4
266
1655
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.3
12.4
120
553
H02AB04
ATC
methylprednisolone; systemic
1.8
12.3
227
1348
JN3AD
NOMESCO Finland
Abdominal CT examination
2.4
12.3
109
480
ZYC01
NOMESCO Finland
Remote contact by phone
3.0
12.3
70
238
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
3.8
12.3
51
137
L57.0
ICD-10 Finland
Actinic keratosis
2.1
12.2
138
681
KA1AE
NOMESCO Finland
Kidney ultrasound examination
3.8
12.2
51
138
QX3AT
NOMESCO Finland
Ultrasound guided biopsy of subcutaneous tissue
18.2
12.0
18
10
PJA10
NOMESCO Finland
Exploration of lymph nodes
18.2
12.0
18
10
N08.4*E85.9
ICD-10 Finland
Glomerular disorders in amyloidosis
26.9
12.0
16
6
N04.9
ICD-10 Finland
Nephrotic syndrome, unspecified
21.5
12.0
17
8
D75.9
ICD-10 Finland
Disease of blood and blood-forming organs, unspecified
10.1
12.0
23
23
NA3DG
NOMESCO Finland
Lumbar spine very extensive MRI examination with high intensity magnet
9.4
12.0
24
26
A41.1
ICD-10 Finland
Sepsis due to other specified staphylococcus
9.4
12.0
24
26
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
3.5
12.0
56
166
WVA20
NOMESCO Finland
Medicine administration
4.3
11.9
43
102
R80
ICD-10 Finland
Isolated proteinuria
8.0
11.8
26
33
L03AA04
ATC
NA
65.4
11.6
13
*
9731/3-C42.1
ICD-O-3
Plasmacytoma, NOS, of bone marrow
65.4
11.6
13
*
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
65.4
11.6
13
*
UJF32
NOMESCO Finland
Coloscopy
1.6
11.6
361
2486
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
11.5
303
1995
C50.51
ICD-10 Finland
Malignant tumor of the lower outer quadrant of the mammary gland, ductal tumor
+∞
11.5
11
*
20399
ICD-8 Finland
Multiple myeloma
+∞
11.5
11
*
L02BX02
ATC
degarelix; parenteral
+∞
11.5
11
*
C92.1
ICD-10 Finland
Chronic myeloid leukaemia [CML], BCR/ABL-positive
+∞
11.5
11
*
C83.00
ICD-10 Finland
Lymphocytic lymphoma
+∞
11.5
11
*
372
Kela drug reimbursment
Idelalisib
+∞
11.5
11
*
C96.9
ICD-10 Finland
Malignant neoplasm of lymphoid, haematopoietic and related tissue, unspecified
+∞
11.5
11
*
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.7
11.4
248
1548
I80.1
ICD-10 Finland
Phlebitis and thrombophlebitis of femoral vein
5.1
11.4
35
70
QBE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin of trunk
2.7
11.4
76
288
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
3.3
11.3
55
169
A07AA09
ATC
vancomycin; oral
5.1
11.1
34
68
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
4.3
11.1
40
95
TQW99
NOMESCO Finland
Other minor procedure on skin
2.9
11.1
68
243
Z2446
NOMESCO Finland
Social worker
2.4
11.0
90
383
J10.0
ICD-10 Finland
Influenza with pneumonia, seasonal influenza virus identified
6.3
10.9
28
45
WX302
NOMESCO Finland
Thoracal epidural anesthesy
4.0
10.9
43
111
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
4.9
10.8
34
70
J20.5
ICD-10 Finland
Acute bronchitis due to respiratory syncytial virus
10.6
10.8
20
19
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
6.2
10.8
28
46
XW3AT
NOMESCO Finland
Biopsy of other superficial organ with ultrasound guidance
28.2
10.7
14
5
THW99
NOMESCO Finland
Other minor procedure in surgery of mammary gland
28.2
10.7
14
5
DHB00
NOMESCO Finland
Excision of lesion of external nose
21.6
10.7
15
7
L27.0
ICD-10 Finland
Generalized skin eruption due to drugs and medicaments
5.5
10.6
30
55
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
5.8
10.6
29
51
J01MA02
ATC
ciprofloxacin; systemic
1.5
10.6
556
4289
121
Kela drug reimbursment
Severe hypofunction of sexual glands
4.8
10.6
34
72
R06.0
ICD-10 Finland
Dyspnoea
1.5
10.5
375
2662
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
2.7
10.4
69
259
399
Kela drug reimbursment
Venetoclax
+∞
10.4
10
*
8310/3-C64.9
ICD-O-3
Clear cell adenocarcinoma, NOS, of kidney, NOS
+∞
10.4
10
*
L01XX47
ATC
[U] idelalisib; oral
+∞
10.4
10
*
C50.11
ICD-10 Finland
Malignant tumor of the central part of the mammary gland,ductal tumor
+∞
10.4
10
*
C50.42
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, lobular tumor
+∞
10.4
10
*
8097/3-C44.9
ICD-O-3
Basal cell carcinoma, nodular of skin, NOS
+∞
10.4
10
*
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
+∞
10.4
10
*
C50.40
ICD-10 Finland
Malignant tumor of the upper outer quadrant of the mammary gland, no histological veryfication
+∞
10.4
10
*
C25.9
ICD-10 Finland
Malignant neoplasm: Pancreas, unspecified
+∞
10.4
10
*
C44.11
ICD-10 Finland
Basocellular carcinoma of the skin of the eyelids including the corner of the eye
+∞
10.4
10
*
C50.81
ICD-10 Finland
Overall malignant tumor of the mammary gland, ductal tumor
+∞
10.4
10
*
QAA05
NOMESCO Finland
Incision for biopsy of skin of head or neck
4.9
10.4
33
69
D47.1
ICD-10 Finland
Chronic myeloproliferative disease
12.1
10.3
18
15
NF1AA
NOMESCO Finland
Hip X-ray examination
1.9
10.3
151
828
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
2.7
10.3
70
270
HA6AA
NOMESCO Finland
Extra corporeal mammography of operated mammary gland
18.9
10.3
15
8
B25.9
ICD-10 Finland
Cytomegaloviral disease, unspecified
23.5
10.2
14
6
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
10.2
464
3470
KE1AT
NOMESCO Finland
Biopsy of prostata with ultrasoudnguidance
3.4
10.1
48
145
M80.8
ICD-10 Finland
Other osteoporosis with pathological fracture
11.4
10.1
18
16
A12AA04
ATC
calcium carbonate; oral
4.0
10.0
39
100
D46.7
ICD-10 Finland
Other myelodysplastic syndromes
14.7
10.0
16
11
C44.41
ICD-10 Finland
Basocellular carcinoma of the skin of the scalp and neck
40.3
10.0
12
*
ZX100
NOMESCO Finland
Oral
5.7
9.8
27
48
L04AA06
ATC
mycophenolic acid; systemic
4.5
9.8
33
74
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.5
9.7
326
2274
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
9.7
301
2061
N03AX12
ATC
gabapentin; oral
1.7
9.7
216
1355
D41.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Kidney
4.5
9.7
33
75
YA1VG
NOMESCO Finland
MRI examination of head and neck with high intesity magnet for dose design of radiotherapy
55.3
9.6
11
*
YNB00
NOMESCO Finland
Excision of bone marrow for transplantation
55.3
9.6
11
*
H26.3
ICD-10 Finland
Drug-induced cataract
8.4
9.6
20
24
EN1AD
NOMESCO Finland
CT examination of mouth and soft tissues of neck
9.1
9.5
19
21
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
9.1
9.5
19
21
D72.8
ICD-10 Finland
Other specified disorders of white blood cells
9.1
9.5
19
21
D59.1
ICD-10 Finland
Other autoimmune haemolytic anaemias
15.1
9.5
15
10
XF400
NOMESCO Finland
ECG with 12 standard connections
1.6
9.5
264
1758
C64
ICD-10 Finland
Malignant neoplasm of kidney, except renal pelvis
100.6
9.4
10
*
E85.3
ICD-10 Finland
Secondary systemic amyloidosis
30.2
9.4
12
*
PJD64
NOMESCO Finland
Laparoscopic dissection of iliac lymph nodes
+∞
9.4
9
*
163
Kela drug reimbursment
Abiraterone and enzalutamide
+∞
9.4
9
*
YJ2VG
NOMESCO Finland
MRI examination of pelvis with high intensity magnet for dose design of radiotherapy
+∞
9.4
9
*
L01XX52
ATC
venetoclax; oral
+∞
9.4
9
*
C81.1
ICD-10 Finland
Nodular sclerosis classical Hodgkin lymphoma
+∞
9.4
9
*
1AA09
NOMESCO Finland
NA
+∞
9.4
9
*
XX1AD
NOMESCO Finland
Other CT-examination
+∞
9.4
9
*
C34.3
ICD-10 Finland
Malignant neoplasm: Lower lobe, bronchus or lung
+∞
9.4
9
*
KE3AT
NOMESCO Finland
Transrectal gold marker implantation in prostate under ultrasound guidance
+∞
9.4
9
*
9731/3-C41.3
ICD-O-3
Plasmacytoma, NOS, of rib, sternum, clavicle and associated joints
+∞
9.4
9
*
C82.01
ICD-10 Finland
Follicular nodular lymphoma, grade I
+∞
9.4
9
*
1XX45
NOMESCO Finland
NA
+∞
9.4
9
*
C34.12
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary adenocarcinoma
+∞
9.4
9
*
D04.3
ICD-10 Finland
Carcinoma in situ: Skin of other and unspecified parts of face
4.8
9.3
30
64
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.2
9.3
92
427
D64.8
ICD-10 Finland
Other specified anaemias
3.9
9.2
36
93
NB3AA
NOMESCO Finland
Clavicle X-ray examination
6.1
9.2
24
40
WX892
NOMESCO Finland
Monitored bed care
2.0
9.2
120
627
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
3.5
9.2
42
124
ZXE20
NOMESCO Finland
More than three and less than five hours
1.7
9.1
179
1083
HA1AT
NOMESCO Finland
Biopsy of mammary glands with ultrasound guidance
10.1
9.0
17
17
KCD05
NOMESCO Finland
Excision of bladder lesion during urinary tract endoscopy with photodynamic diagnosis (PDD)
36.9
9.0
11
*
B01AB04
ATC
dalteparin; parenteral
2.4
9.0
72
305
N18.0
ICD-10 Finland
End-stage renal disease
4.1
9.0
33
81
B00.2
ICD-10 Finland
Herpesviral gingivostomatitis and pharyngotonsillitis
18.7
8.9
13
7
PJ2AE
NOMESCO Finland
Lymphnode ultrasound examination
7.5
8.9
20
27
L04AA01
ATC
[U] ciclosporin; systemic
4.4
8.9
31
72
UJF30
NOMESCO Finland
Ileoscopy through colon
1.9
8.9
132
727
QBA25
NOMESCO Finland
Destruction of lesion of skin of trunk
6.1
8.9
23
38
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.0
8.8
105
534
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
8.8
466
3575
WD315
NOMESCO Finland
Multiple therapy of methastized malignancy with biomodifiers
50.2
8.7
10
*
D05.1
ICD-10 Finland
Intraductal carcinoma in situ
50.2
8.7
10
*
C67.9
ICD-10 Finland
Malignant neoplasm: Bladder, unspecified
50.2
8.7
10
*
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.1
8.7
99
491
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
7.7
8.6
19
25
M54.5
ICD-10 Finland
Low back pain
1.5
8.6
408
3058
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
16.4
8.6
13
8
D48.9
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Neoplasm of uncertain or unknown behaviour, unspecified
4.6
8.5
28
62
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
1.9
8.5
115
614
GA6AA
NOMESCO Finland
Sternal X-ray examination
27.7
8.5
11
*
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
4.0
8.5
32
81
WF029
NOMESCO Finland
Radiotherapy of local residive tumor
90.5
8.4
9
*
WF090
NOMESCO Finland
Profylactic radiotherapy
90.5
8.4
9
*
M48.5
ICD-10 Finland
Collapsed vertebra, not elsewhere classified
7.9
8.4
18
23
AA1BD
NOMESCO Finland
Extensive CT of head and brain
3.7
8.4
35
97
128
Kela drug reimbursment
Cancers of female genital organs
+∞
8.3
8
*
C54.11
ICD-10 Finland
Adenocarcinoma of the endometrium
+∞
8.3
8
*
8140/3-C20.9
ICD-O-3
Adenocarcinoma, NOS, of rectum, NOS
+∞
8.3
8
*
DAB10
NOMESCO Finland
Partial excision of auricle
+∞
8.3
8
*
8120/3-C67.9
ICD-O-3
Transitional cell carcinoma, NOS, of bladder, NOS
+∞
8.3
8
*
8500/3-C50.4
ICD-O-3
Infiltrating duct carcinoma, NOS, of upper-outer quadrant of breast
+∞
8.3
8
*
C50.90
ICD-10 Finland
Malignant tumor in other or unspecified location in mammary gland without histology
+∞
8.3
8
*
C50.31
ICD-10 Finland
Malignant tumor of the lower inner quadrant of the mammary gland, ductal tumor
+∞
8.3
8
*
HAB50
NOMESCO Finland
Partial excision of mammary gland with reconstructive operation
+∞
8.3
8
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
+∞
8.3
8
*
C34.10
ICD-10 Finland
Malignant tumor of the upper lobe, bronchus or lung without histology
+∞
8.3
8
*
9731/3-C41.2
ICD-O-3
Plasmacytoma, NOS, of vertebral column
+∞
8.3
8
*
C83.3
ICD-10 Finland
Diffuse large B-cell lymphoma
+∞
8.3
8
*
C18.20
ICD-10 Finland
Malignant tumor of the ascending colon without histology
+∞
8.3
8
*
NAR00
NOMESCO Finland
Complete excision of tumour of bone or cartilage of spine, unspecified
+∞
8.3
8
*
9761/3-C42.0
ICD-O-3
Waldenstrom macroglobulinemia of blood
+∞
8.3
8
*
KEC00
NOMESCO Finland
Retropubic radical prostatectomy
+∞
8.3
8
*
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.1
8.3
88
425
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.7
8.3
53
197
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
8.3
206
1330
J02AC01
ATC
fluconazole; systemic
1.4
8.2
432
3299
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.3
8.2
77
351
D69.3
ICD-10 Finland
Idiopathic thrombocytopenic purpura
7.6
8.2
18
24
B03BA03
ATC
hydroxocobalamin; parenteral
2.0
8.1
102
529
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
1.9
8.1
125
698
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.4
8.1
68
294
D69.5
ICD-10 Finland
Secondary thrombocytopenia
17.3
8.1
12
7
F43.29
ICD-10 Finland
Adaptation disorder UNS
4.6
8.0
26
57
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.3
8.0
73
329
ECB20
NOMESCO Finland
Oral alveoplasty
5.0
7.9
24
49
S42.3
ICD-10 Finland
Fracture of shaft of humerus
4.1
7.9
29
72
R74.8
ICD-10 Finland
Abnormal levels of other serum enzymes
2.6
7.8
54
211
L01BB02
ATC
mercaptopurine; oral
7.0
7.8
18
26
JN4JR
NOMESCO Finland
Whole body extensive metabolic PET with CT
15.1
7.7
12
8
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.4
7.7
61
258
D62
ICD-10 Finland
Acute posthaemorrhagic anaemia
5.3
7.7
22
42
J01FF01
ATC
clindamycin; systemic
1.5
7.7
347
2566
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
4.8
7.6
24
51
PJD42
NOMESCO Finland
Excision of axillary lymph nodes
18.4
7.6
11
6
ZYC05
NOMESCO Finland
Non-real-time text-based remote communication
6.7
7.6
18
27
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
6.7
7.6
18
27
PJ2AT
NOMESCO Finland
Biopsy of lymphnode with ultrasound guidance
25.1
7.6
10
*
J94.8
ICD-10 Finland
Other specified pleural conditions
4.3
7.5
26
61
L28
ICPC
Limited function/disability (L)
1.5
7.5
247
1709
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
2.4
7.5
61
260
J20.4
ICD-10 Finland
Acute bronchitis due to parainfluenza virus
80.4
7.4
8
*
ZXA00
NOMESCO Finland
Right side
1.4
7.4
382
2899
V03AE01
ATC
polystyrene sulfonate; oral
3.8
7.4
29
77
SAA04
NOMESCO Finland
Special inverstigation of mouth
2.3
7.4
67
304
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.7
7.3
148
900
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.2
7.3
71
329
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
7.3
588
4817
NB6AD
NOMESCO Finland
Upper arm CT
+∞
7.3
7
*
GA5DA
NOMESCO Finland
Bilateral rib X-ray exmaination
+∞
7.3
7
*
C25.0
ICD-10 Finland
Malignant neoplasm: Head of pancreas
+∞
7.3
7
*
L02BB04
ATC
enzalutamide; oral
+∞
7.3
7
*
C95.0
ICD-10 Finland
Acute leukaemia of unspecified cell type
+∞
7.3
7
*
J12.2
ICD-10 Finland
Parainfluenza virus pneumonia
+∞
7.3
7
*
C09.0
ICD-10 Finland
Malignant neoplasm: Tonsillar fossa
+∞
7.3
7
*
C50.4
ICD-10 Finland
Malignant neoplasm: Upper-outer quadrant of breast
+∞
7.3
7
*
C50.9
ICD-10 Finland
Malignant neoplasm: Breast, unspecified
+∞
7.3
7
*
C80.90
ICD-10 Finland
Malignant tumor without specified localization without histology
+∞
7.3
7
*
C43.52
ICD-10 Finland
Malignant melanoma on the torso: 'superficial spreading' type
+∞
7.3
7
*
L03AA10
ATC
lenograstim; parenteral
+∞
7.3
7
*
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
+∞
7.3
7
*
NA049
NOMESCO Finland
Radiotherapy of methastasis in spine
+∞
7.3
7
*
8140/3-C18.2
ICD-O-3
Adenocarcinoma, NOS, of ascending colon
+∞
7.3
7
*
197
Kela drug reimbursment
Sunitinib
+∞
7.3
7
*
WD205
NOMESCO Finland
Therapy of methastized malignancy with hormones
+∞
7.3
7
*
A21
ICPC
Risk factor for malignancy
+∞
7.3
7
*
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
4.9
7.3
22
45
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
5.2
7.2
21
41
WX720
NOMESCO Finland
Own respiration
2.4
7.2
57
240
9961/3-C42.1
ICD-O-3
Primary myelofibrosis of bone marrow
15.8
7.2
11
7
TPX15
NOMESCO Finland
Removal of vascular injection port
15.8
7.2
11
7
B99
ICPC
Blood/lymph/spleen disease other
7.3
7.2
16
22
E83.51
ICD-10 Finland
Hypocalcemia
7.3
7.2
16
22
C08CA01
ATC
amlodipine; oral
1.4
7.1
569
4645
D80.9
ICD-10 Finland
Immunodeficiency with predominantly antibody defects, unspecified
30.1
7.1
9
*
K10.21
ICD-10 Finland
Osteoradionecrosis of jaw (acute)(chronic)(suppurative)
30.1
7.1
9
*
N06DA02
ATC
donepezil; oral
0.4
7.1
28
687
K10.25
ICD-10 Finland
Sequences of jawbones
12.1
7.1
12
10
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.7
7.1
149
921
N02AA01
ATC
morphine; systemic, rectal
5.6
7.1
19
34
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.5
7.0
229
1579
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.2
7.0
67
312
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
4.5
7.0
23
52
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
6.9
579
4759
B01.9
ICD-10 Finland
Varicella without complication
13.8
6.9
11
8
D23.1
ICD-10 Finland
Benign neoplasm: Skin of eyelid, including canthus
2.6
6.9
48
189
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
2.4
6.9
55
235
R11
ICD-10 Finland
Nausea and vomiting
1.8
6.8
107
601
D04.4
ICD-10 Finland
Carcinoma in situ: Skin of scalp and neck
9.3
6.8
13
14
ZXC20
NOMESCO Finland
Use of chemical agents
3.7
6.8
27
73
ZXC96
NOMESCO Finland
Robot assisted procedure
6.1
6.8
17
28
KAC10
NOMESCO Finland
Total nephrectomy with capsule
16.8
6.7
10
6
R93.7
ICD-10 Finland
Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
16.8
6.7
10
6
WX002
NOMESCO Finland
Sedation and analgesia
1.5
6.7
269
1938
N06DX01
ATC
memantine; oral
0.4
6.7
37
801
5AB14
NOMESCO Finland
NA
22.6
6.7
9
*
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
2.4
6.6
53
226
PJ3AT
NOMESCO Finland
Cytology of lymphnode with ultrasound guidance
12.3
6.6
11
9
N05AX08
ATC
risperidone; systemic
0.5
6.5
38
805
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.3
6.5
58
261
R04.0
ICD-10 Finland
Epistaxis
1.8
6.5
115
675
TK810
NOMESCO Finland
Hemofiltration
5.3
6.5
18
34
C44.21
ICD-10 Finland
Basocellular carcinoma of the skin of the outer ear and the outer ear canal
70.1
6.4
7
*
N08.2*D89.82
ICD-10 Finland
Nepropathy caused by deposition of the light chain of the immunoglobulins
70.1
6.4
7
*
L02AE04
ATC
triptorelin; parenteral
70.1
6.4
7
*
J12.9
ICD-10 Finland
Viral pneumonia, unspecified
7.4
6.4
14
19
NF3AD
NOMESCO Finland
Femur CT
14.4
6.4
10
7
D47.3
ICD-10 Finland
Essential (haemorrhagic) thrombocythaemia
4.9
6.4
19
39
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.4
6.3
326
2466
8520/3-C50.9
ICD-O-3
Lobular carcinoma, NOS, of breast, NOS
+∞
6.3
6
*
C18.01
ICD-10 Finland
Malignant tumor of the caecum invasive carcinoma
+∞
6.3
6
*
1518
Kela drug reimbursment
NA
+∞
6.3
6
*
9733/3-C42.1
ICD-O-3
Plasma cell leukemia of bone marrow
+∞
6.3
6
*
C83.80
ICD-10 Finland
B-cell lymphoma in marginal zone
+∞
6.3
6
*
JN5PN
NOMESCO Finland
Isotope imaging of secondary neoplasms of thyroid origin
+∞
6.3
6
*
8500/2-C50.9
ICD-O-3
Intraductal carcinoma, noninfiltrating, NOS, of breast, NOS
+∞
6.3
6
*
C34.90
ICD-10 Finland
Malignant tumor in unspecified location in bronchus and lung without histology
+∞
6.3
6
*
198
Kela drug reimbursment
Sorafenib
+∞
6.3
6
*
9680/3-C77.9
ICD-O-3
Diffuse large B-cell lymphoma, NOS, of lymph node, NOS
+∞
6.3
6
*
WD225
NOMESCO Finland
Demanding therapy of methastized malignancy with hormones
+∞
6.3
6
*
5BX04
NOMESCO Finland
NA
+∞
6.3
6
*
C34.32
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung adenocarcinoma
+∞
6.3
6
*
8380/3-C54.1
ICD-O-3
Endometrioid adenocarcinoma, NOS, of endometrium
+∞
6.3
6
*
C85.1
ICD-10 Finland
B-cell lymphoma, unspecified
+∞
6.3
6
*
WB401
NOMESCO Finland
Simple antibody therapy of primary tumour
+∞
6.3
6
*
WB323
NOMESCO Finland
Demanding adjuvant therapy of malignancy with biomodifiers
+∞
6.3
6
*
YA1CD
NOMESCO Finland
Very extensive CT examination of head and neck for dose design of radiotherapy
+∞
6.3
6
*
C95.9
ICD-10 Finland
Leukaemia, unspecified
+∞
6.3
6
*
2AX04
NOMESCO Finland
NA
+∞
6.3
6
*
C22.0
ICD-10 Finland
Malignant neoplasm: Liver cell carcinoma
+∞
6.3
6
*
L02BG06
ATC
exemestane; oral
+∞
6.3
6
*
C44.39
ICD-10 Finland
Malignant tumor of the skin on another or unspecified part of the face other or unspecified histology
+∞
6.3
6
*
8090/3-C44.1
ICD-O-3
Basal cell carcinoma, NOS, of eyelid
+∞
6.3
6
*
C30.0
ICD-10 Finland
Malignant neoplasm: Nasal cavity
+∞
6.3
6
*
NFR20
NOMESCO Finland
Incomplete excision of soft tissue tumour of hip or thigh
26.8
6.2
8
*
Z94.9
ICD-10 Finland
Transplanted organ and tissue status, unspecified
26.8
6.2
8
*
ZX121
NOMESCO Finland
Central venous catheter
26.8
6.2
8
*
D80.1
ICD-10 Finland
Nonfamilial hypogammaglobulinaemia
26.8
6.2
8
*
L02BG03
ATC
anastrozole; oral
26.8
6.2
8
*
XQ848
NOMESCO Finland
Dermatological photography
3.0
6.2
33
112
Z3226
NOMESCO Finland
Physiotherapist
1.5
6.2
233
1654
R79.8
ICD-10 Finland
Other specified abnormal findings of blood chemistry
6.3
6.2
15
24
WW200
SPAT
NA
0.5
6.2
40
820
G30.1
ICD-10 Finland
Alzheimer disease with late onset
0.4
6.1
32
705
J12.8
ICD-10 Finland
Other viral pneumonia
4.7
6.1
19
41
K10.20
ICD-10 Finland
Osteomyelitis (neonatal) of jaw (acute)(chronic)(suppurative)
12.6
6.1
10
8
L02AE03
ATC
goserelin; implant
12.6
6.1
10
8
S77
ICPC
Malignant neoplasm of skin
12.6
6.1
10
8
ZXC40
NOMESCO Finland
Use of ultrasound
8.6
6.1
12
14
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.5
6.0
243
1752
ZXC50
NOMESCO Finland
Cryotherapy
2.7
6.0
37
138
R52.0
ICD-10 Finland
Acute pain
2.8
6.0
35
125

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: CD2_MULTIPLE_MYELOMA_PLASMA_CELL_EXALLC – Multiple myeloma and malignant plasma cell neoplasms

GWS hits: 2

This endpoint is excluded (different definition than used in FinnGen).