This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Mental and behavioural disorders associated with the puerperium
F5_MENTPUER
postpartum depression: An endogenous depression that involves intense, sustained and sometimes disabling depression experienced by women after giving birth.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleonly females |
293373 |
2. Check conditionsNone |
293373 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
425 |
4. Check minimum number of eventsNone |
425 |
5. Include endpointsNone |
425 |
6. Filter based on genotype QC (FinnGen only) |
425 |
Control definitions (FinnGen only)
- Control exclude
- F5_BEHAVE
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- F50-F59
- Name in latin
- Perturbationes mentis et modi se gerendi puerperio adjunctae non alibi classificatae
Similar endpoints
↥List of similar endpoints to
Mental and behavioural disorders associated with the puerperium
based on the number of shared cases.
Similar with more cases:
- Mental and behavioural disorders of puerperium, not classified elsewhere
- Mental and behabioural disorders of puerperum, not classified elsewhere, excluding more controls
- Behavioural syndromes associated with physiological disturbances and physical factors
- Any mental disorder
- Psychiatric diseases
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 425 | 425 | - |
| Unadjusted period prevalence (%) | 0.14 | 0.14 | - |
| Median age at first event (years) | 30.32 | 30.32 | - |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 388
- Matched controls
- 3880
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F53.0
ICD-10 Finland
Mild mental and behavioural disorders associated with the puerperium, not elsewhere classified
2851.3
186.1
165
*
F53.1
ICD-10 Finland
Severe mental and behavioural disorders associated with the puerperium, not elsewhere classified
+∞
123.7
112
*
29440
ICD-8 Finland
Psychosis associated with other physical conditions, Childbirth
+∞
80.0
74
*
N05AH04
ATC
quetiapine; oral
8.8
74.1
196
404
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
15.5
74.1
130
122
F53.9
ICD-10 Finland
Puerperal mental disorder, unspecified
+∞
65.5
61
*
N05AH03
ATC
olanzapine; systemic
14.1
57.9
104
98
N05BA04
ATC
oxazepam; oral
5.5
51.3
205
652
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
15.8
44.7
75
58
F29
ICD-10 Finland
Unspecified nonorganic psychosis
14.5
42.0
73
61
F32.9
ICD-10 Finland
Depressive episode, unspecified
5.4
37.5
132
338
N06AB06
ATC
sertraline; oral
5.6
33.9
112
262
N05AX08
ATC
risperidone; systemic
8.8
32.5
73
99
N05AX12
ATC
aripiprazole; systemic
9.6
30.3
64
78
N03AG01
ATC
valproic acid; systemic, rectal
7.3
28.2
72
118
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
12.3
26.7
49
45
N05AB03
ATC
perphenazine; systemic, rectal
11.1
26.4
51
52
N05AA02
ATC
levomepromazine; systemic
13.6
25.8
45
37
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
4.8
24.9
93
241
N06AB04
ATC
citalopram; systemic
3.6
24.9
139
521
N05AN01
ATC
lithium; oral
12.9
24.7
44
38
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
4.3
23.8
101
296
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
12.6
22.8
41
36
N05CD07
ATC
temazepam; oral
6.1
21.7
62
117
N05AA01
ATC
chlorpromazine; systemic, rectal
28.3
21.7
29
11
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
5.4
21.2
68
148
N06AX11
ATC
mirtazapine; oral
3.0
21.1
165
767
N05BA06
ATC
lorazepam; systemic, sublingual
9.4
21.0
44
52
O99.80
ICD-10 Finland
The fear of childbirth
4.5
20.2
78
206
N05AD01
ATC
haloperidol; systemic
16.5
20.1
32
21
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
12.3
19.9
36
32
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
9.3
18.7
39
46
F31.0
ICD-10 Finland
Bipolar affective disorder, current episode hypomanic
17.3
18.6
29
18
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
10.3
18.3
36
38
F53.8
ICD-10 Finland
Other mental and behavioural disorders associated with the puerperium, not elsewhere classified
+∞
17.8
17
*
N05AC02
ATC
thioridazine; oral
14.0
17.8
30
23
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
5.7
17.6
52
102
N04AA02
ATC
biperiden; systemic
18.5
17.2
26
15
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
7.4
17.0
41
61
N05CF01
ATC
zopiclone; oral
2.8
16.8
136
628
P76
ICPC
Depressive disorder
4.4
16.7
64
167
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
3.8
16.5
77
240
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
4.4
16.5
63
164
N06AX16
ATC
venlafaxine; oral
3.2
16.3
100
383
F31.20
ICD-10 Finland
Bipolar disorder, manic episode with mood-congruent psychotic symptoms
25.8
16.2
22
9
ZY000
NOMESCO Finland
Hospital inpatient
15.6
15.6
25
17
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
4.7
15.0
53
127
N06AB03
ATC
fluoxetine; oral
3.4
15.0
81
282
P29
ICPC
Psychological sympt/compl other
4.5
14.3
53
133
N06AB05
ATC
paroxetine; oral
4.6
13.9
49
117
N05AF03
ATC
chlorprothixene; systemic
8.0
13.4
30
40
Z2446
NOMESCO Finland
Social worker
4.5
13.4
48
117
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
14.7
12.9
21
15
N03AX09
ATC
lamotrigine; oral
4.2
12.7
49
128
2988A
ICD-9 Finland
Other nonorganic psychoses, Other and unspecified reactive psychosis
+∞
12.6
12
*
P01
ICPC
Feeling anxious/nervous/tense
2.8
12.3
90
381
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
2.6
12.1
102
469
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
2.1
11.9
206
1339
T36
ICD-10 Finland
Poisoning by systemic antibiotics
5.3
11.9
36
73
IGY02
NOMESCO Finland
Psychiatric monitoring contact
7.1
11.7
28
42
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
10.1
11.4
22
23
F20.9
ICD-10 Finland
Schizophrenia, unspecified
10.0
10.9
21
22
SPAT1240
SPAT
Therapeutic discussion
2.7
10.8
82
354
F51.0
ICD-10 Finland
Nonorganic insomnia
2.7
10.8
78
326
P99
ICPC
Psychological disorders other
5.9
10.6
29
52
F31.8
ICD-10 Finland
Other bipolar affective disorders
6.7
10.5
26
41
ZY010
NOMESCO Finland
Hospital outpatient
3.8
10.4
44
125
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
2.1
9.9
147
876
29999
ICD-8 Finland
Unspecified psychosis
56.4
9.7
11
*
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
6.0
9.7
26
46
F33.30
ICD-10 Finland
Recurrent depression, severe episode without somatic syndrome
8.7
9.7
20
24
N06AB10
ATC
escitalopram; oral
2.2
9.6
123
684
N06AA12
ATC
doxepin; systemic
5.4
9.6
28
55
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
2.7
9.6
68
279
2989X
ICD-9 Finland
Other nonorganic psychoses, Unspecified psychosis
18.1
9.5
14
8
P06
ICPC
Sleep disturbance
3.0
9.5
57
211
Z35
ICD-10 Finland
Supervision of high-risk pregnancy
12.8
9.4
16
13
O80.0
ICD-10 Finland
Spontaneous vertex delivery
2.0
9.4
211
1467
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
5.5
9.1
26
50
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
5.9
8.6
23
41
P74
ICPC
Anxiety disorder/anxiety state
3.8
8.5
35
98
R3110
NOMESCO Finland
Psychosocial training
5.3
8.5
25
50
IFA01
NOMESCO Finland
Psychiatric pharmacotherapy plan, not specified
7.0
8.5
20
30
F31.4
ICD-10 Finland
Bipolar affective disorder, current episode severe depression without psychotic symptoms
8.1
8.5
18
23
G02CB01
ATC
bromocriptine; systemic
6.1
8.4
22
38
F25.00
ICD-10 Finland
Schizoaffective syndrome, manic type with only simultaneous bipolar and schizophrenic symptoms
14.9
8.3
13
9
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
2.3
8.2
81
399
N05BA12
ATC
alprazolam; oral
2.8
8.2
52
201
F31.1
ICD-10 Finland
Bipolar affective disorder, current episode manic without psychotic symptoms
12.0
8.1
14
12
F33.3
ICD-10 Finland
Recurrent depressive disorder, current episode severe with psychotic symptoms
34.1
8.1
10
*
P72
ICPC
Schizophrenia
8.0
8.0
17
22
IGY99
NOMESCO Finland
Other psychiatric treatment contact
5.9
7.9
21
37
T90
ICPC
Diabetes non-insulin dependent
2.7
7.9
56
231
N06AX12
ATC
bupropion; oral
2.8
7.7
49
189
N05AF05
ATC
zuclopenthixol; systemic
12.2
7.6
13
11
188
Kela drug reimbursment
Psychosis requiring demanding treatment
10.3
7.6
14
14
ZYC01
NOMESCO Finland
Remote contact by phone
3.7
7.5
31
88
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
5.8
7.5
20
36
F31.21
ICD-10 Finland
Bipolar disorder, manic episode with mood incongruent psychotic symptoms
81.6
7.4
8
*
F31.5
ICD-10 Finland
Bipolar affective disorder, current episode severe depression with psychotic symptoms
13.7
7.4
12
9
N05BA01
ATC
diazepam; systemic, rectal
2.6
7.3
53
222
P98
ICPC
Psychosis NOS/other
16.1
7.3
11
7
F60.9
ICD-10 Finland
Personality disorder, unspecified
7.5
7.3
16
22
P73
ICPC
Affective psychosis
30.6
7.2
9
*
SPAT1389
SPAT
Visit based on need for special support
4.5
7.2
24
56
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
3.4
7.2
34
108
SPAT1241
SPAT
Extensive assessment of psychosocial situation
9.0
7.1
14
16
F31
ICD-10 Finland
Bipolar affective disorder
9.0
7.1
14
16
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
4.6
7.1
23
52
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
7.2
7.1
16
23
F41.1
ICD-10 Finland
Generalized anxiety disorder
2.9
7.0
41
150
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
1.8
7.0
138
892
A06AD11
ATC
lactulose; oral
3.0
7.0
40
145
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
3.6
6.9
29
84
N05CF02
ATC
zolpidem; oral
2.1
6.8
81
430
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.2
6.8
34
113
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
2.0
6.6
89
496
F31.3
ICD-10 Finland
Bipolar affective disorder, current episode mild or moderate depression
8.9
6.6
13
15
W78
ICPC
Pregnancy
1.8
6.6
132
853
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
3.3
6.5
31
99
N06AX03
ATC
mianserin; oral
3.8
6.5
26
72
N05BE01
ATC
buspirone; oral
5.1
6.4
19
39
29580
ICD-8 Finland
Schizophrenia, Other
71.0
6.4
7
*
2957A
ICD-9 Finland
Schizophrenic psychoses, Schizo-affective type
71.0
6.4
7
*
Z2445
NOMESCO Finland
Psychologist
3.6
6.4
27
79
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
2.0
6.3
82
452
IGP01
NOMESCO Finland
Psychiatric family contact
18.4
6.3
9
5
F28
ICD-10 Finland
Other nonorganic psychotic disorders
18.4
6.3
9
5
ZXY83
NOMESCO Finland
Social worker in multidisciplinary team
27.1
6.2
8
*
N06AA22
ATC
NA
27.1
6.2
8
*
2954A
ICD-9 Finland
Schizophrenic psychoses, Acute schizophrenic episode
27.1
6.2
8
*
N06AB08
ATC
fluvoxamine; oral
5.5
6.2
17
32
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
4.4
6.2
21
50
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
2.1
6.2
79
430
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
2.2
6.2
63
310
N06AX05
ATC
trazodone; oral
5.7
6.1
16
29
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: F5_MENTPUER – Mental and behavioural disorders associated with the puerperium
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).