pleural empyema: The presence of pus in the thoracic cavity, between the visceral and parietal pleura. [database_cross_reference: NCIT:P378]
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2784 |
4. Check minimum number of eventsNone |
2784 |
5. Include endpointsNone |
2784 |
6. Filter based on genotype QC (FinnGen only) |
2784 |
Control definitions (FinnGen only)
- Control exclude
- J10_LOWCHRON
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- J40-J47
- Name in latin
- Emphysema pulmonale
Similar endpoints
↥List of similar endpoints to
Emphysema
based on the number of shared cases.
Similar with more cases:
- COPD
- Chronic lower respiratory diseases
- Excluding asthma or asthma-COPD overlap
- COPD differential diagnosis
- ILD differential diagnosis
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 25262 | 6005 | 18635 |
| Only index persons | 14435 | 4338 | 10097 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.44 | 0.17 | 0.52 |
| Only index persons | 0.32 | 0.16 | 0.39 |
| Median age at first event (years) | |||
| Whole population | 68.18 | 67.77 | 68.36 |
| Only index persons | 67.82 | 66.92 | 68.21 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2784 | 747 | 2037 |
| Unadjusted period prevalence (%) | 0.73 | 0.25 | 0.90 |
| Median age at first event (years) | 69.06 | 65.35 | 70.42 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2446
- Matched controls
- 24455
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
R03BB04
ATC
tiotropium bromide; inhalant
58.5
323.0
1080
326
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
+∞
323.0
932
*
R03AC02
ATC
salbutamol; inhalant
7.0
323.0
1617
5349
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
443.6
323.0
673
21
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
468.6
323.0
462
12
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
212.8
323.0
1325
135
J45.9
ICD-10 Finland
Asthma, unspecified
43.8
323.0
654
202
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
225.2
323.0
544
31
J43.9
ICD-10 Finland
Emphysema, unspecified
6276.0
323.0
1649
8
J43.2
ICD-10 Finland
Centrilobular emphysema
+∞
323.0
345
*
R03AK06
ATC
salmeterol and fluticasone; inhalant
17.8
323.0
740
583
H02AB06
ATC
prednisolone; systemic
4.9
289.9
1531
6245
J45.1
ICD-10 Finland
Nonallergic asthma
243.9
277.5
281
13
J43.8
ICD-10 Finland
Other emphysema
2772.2
274.0
260
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
7.7
268.1
704
1220
R95
ICPC
Chron obstructive pulmonary disease
53.7
248.7
298
63
R03DA04
ATC
theophylline; systemic, rectal
18.8
244.6
388
242
R03AK03
ATC
[D] fenoterol & other drugs for obstructive airway dis; inhalant
13.1
234.7
435
396
R06.0
ICD-10 Finland
Dyspnoea
4.8
232.9
1001
3099
J96.1
ICD-10 Finland
Chronic respiratory failure
39.0
231.5
296
86
R03AK07
ATC
formoterol and budesonide; inhalant
7.3
228.7
614
1072
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
13.7
223.4
405
349
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
226.1
221.6
226
11
UGC12
NOMESCO Finland
Flexible bronchoscopy
8.0
216.3
541
843
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
52.7
205.4
247
52
J18.9
ICD-10 Finland
Pneumonia, unspecified
4.0
205.0
1147
4430
R03AC12
ATC
salmeterol; inhalant
52.6
197.9
238
50
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
73.4
193.9
221
33
J45.0
ICD-10 Finland
Predominantly allergic asthma
135.2
187.3
199
16
R03BA02
ATC
budesonide; inhalant
6.5
163.4
466
850
R03BA01
ATC
beclometasone; inhalant
7.5
161.2
411
639
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
10.6
159.0
325
348
R03AC13
ATC
formoterol; inhalant
25.3
154.2
220
95
R03BA05
ATC
fluticasone; inhalant
5.6
147.7
477
1008
R03BB01
ATC
ipratropium bromide; inhalant
11.9
141.8
272
255
R03AL08
ATC
vilanterol, umeclidinium bromide and fluticasone furoate; inhalant
188.2
137.1
142
8
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
4.7
130.5
499
1258
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.8
128.8
1350
7406
J45
ICD-10 Finland
Asthma
13.9
124.4
221
174
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
5.9
123.2
377
735
J43.1
ICD-10 Finland
Panlobular emphysema
+∞
119.8
114
*
R02
ICPC
Shortness of breath/dyspnoea
4.6
117.6
456
1155
J47
ICD-10 Finland
Bronchiectasis
311.8
117.2
118
*
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
17.7
116.1
186
113
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
12.9
114.0
209
176
R96
ICPC
Asthma
13.0
112.8
206
172
R03DC03
ATC
montelukast; oral
5.6
105.7
337
684
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
11.6
105.2
203
190
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
6.1
103.7
303
552
R03AC03
ATC
terbutaline; inhalant
5.1
102.6
351
771
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
3.5
100.3
550
1871
XG410
NOMESCO Finland
Flow-volume spirometry
9.1
97.3
214
255
J45.8
ICD-10 Finland
Mixed asthma
201.8
94.0
97
5
J01MA14
ATC
moxifloxacin; systemic
4.7
92.9
347
833
GD1AD
NOMESCO Finland
Thorax CT examination
7.3
92.7
236
354
4912B
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS OBSTRUCTIVA CUM EMPHYSEMATE]
+∞
92.3
88
*
J46
ICD-10 Finland
Status asthmaticus
144.1
91.7
97
7
R03AK08
ATC
formoterol and beclometasone; inhalant
30.7
89.2
120
41
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
298.6
85.2
86
*
N07BA03
ATC
varenicline; oral
7.6
81.9
202
288
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
9.5
80.5
171
191
R03BA08
ATC
ciclesonide; inhalant
7.8
80.3
194
268
J01AA02
ATC
doxycycline; systemic
2.4
79.8
1859
13866
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.8
74.6
562
2334
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
20.0
72.8
111
58
C03CA01
ATC
furosemide; systemic
2.2
72.8
1028
5959
H02AB07
ATC
prednisone; oral
3.3
71.9
419
1459
R03AC18
ATC
indacaterol; inhalant
52.3
71.8
86
17
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
8.1
71.6
167
218
J43
ICD-10 Finland
Emphysema
+∞
70.1
67
*
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.2
67.7
1104
6757
J93.1
ICD-10 Finland
Other spontaneous pneumothorax
20.4
67.5
102
52
I50.9
ICD-10 Finland
Heart failure, unspecified
2.6
64.8
560
2493
R04.2
ICD-10 Finland
Haemoptysis
6.1
64.1
184
322
J01MA12
ATC
levofloxacin; systemic
2.5
62.0
596
2809
R03AL03
ATC
vilanterol and umeclidinium bromide; inhalant
30.2
61.0
82
28
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.3
60.7
338
1129
J01FA06
ATC
roxithromycin; oral
2.1
60.1
938
5549
R03AL04
ATC
indacaterol and glycopyrronium bromide; inhalant
208.3
59.3
61
*
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
44.2
59.1
73
17
TGC00
NOMESCO Finland
Bronchial lavation
7.9
59.0
140
187
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
5.5
58.9
185
361
R03AK11
ATC
formoterol and fluticasone; inhalant
26.6
57.6
80
31
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
13.9
54.4
95
71
49300
ICD-8 Finland
Asthma, bronchiale
+∞
54.4
52
*
49209
ICD-8 Finland
Emphysema, Unspecified
+∞
52.3
50
*
4939X
ICD-9 Finland
Asthma, unspecified[ASTHMA BRONCHIALE NUD]
+∞
51.2
49
*
XG466
NOMESCO Finland
Sleep oxymetry
6.1
51.2
146
253
J43.0
ICD-10 Finland
MacLeod syndrome
+∞
50.2
48
*
348
Kela drug reimbursment
Roflumilast
+∞
50.2
48
*
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
14.7
47.7
81
57
Z72.0
ICD-10 Finland
Tobacco use
8.2
46.1
106
135
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.5
46.1
404
1780
A02BC02
ATC
pantoprazole; systemic
1.8
45.9
1481
11093
R03DX07
ATC
roflumilast; oral
+∞
43.9
42
*
R28
ICPC
Limited function/disability (R)
14.3
43.7
75
54
R03BB06
ATC
glycopyrronium bromide; inhalant
95.8
42.9
47
5
C07AB07
ATC
bisoprolol; oral
1.8
42.8
1277
9216
E88.0
ICD-10 Finland
Disorders of plasma-protein metabolism, not elsewhere classified
91.7
40.9
45
5
4920A
ICD-9 Finland
Emphysematous bleb
+∞
40.7
39
*
H02AB04
ATC
methylprednisolone; systemic
2.6
40.7
327
1366
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
6.7
39.9
104
160
R03BB07
ATC
umeclidinium bromide; inhalant
30.6
38.3
51
17
R03AC19
ATC
olodaterol; inhalant
135.4
37.8
40
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.9
36.4
735
4586
ZX109
NOMESCO Finland
Instruction on medicine inhalation technique
36.0
36.0
46
13
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.1
35.6
491
2652
J42
ICD-10 Finland
Unspecified chronic bronchitis
21.7
34.9
51
24
XG460
NOMESCO Finland
Short time oxymetry
6.3
34.7
94
153
R81
ICPC
Pneumonia
4.6
34.2
124
283
N02AX02
ATC
tramadol; systemic, rectal
1.7
34.0
1009
7082
R06.2
ICD-10 Finland
Wheezing
5.4
34.0
105
201
N05CF01
ATC
zopiclone; oral
1.8
33.8
826
5461
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.8
33.5
116
252
49104
ICD-8 Finland
Chronic bronchitis, Cum emphysemate
+∞
33.4
32
*
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
9.3
33.3
70
77
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
20.8
33.1
49
24
A07AA02
ATC
nystatin; oral
3.2
32.3
179
587
SPAT1059
SPAT
Spirometry at the office
4.0
31.8
133
348
J92.0
ICD-10 Finland
Pleural plaque with presence of asbestos
5.1
31.6
102
206
4928X
ICD-9 Finland
Emphysema, Other emphysema[EMPHYSEMA ALIA DEFINITA]
+∞
31.3
30
*
4931A
ICD-9 Finland
Asthma, Intrinsic asthma[INTRINSIC ASTHMA SINE EXACERBATIONE]
+∞
31.3
30
*
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.9
31.3
560
3322
WX725
NOMESCO Finland
Noninvasive ventilation
3.8
30.8
135
368
I50.0
ICD-10 Finland
Congestive heart failure
2.4
30.8
284
1269
J93.9
ICD-10 Finland
Pneumothorax, unspecified
15.9
30.8
50
32
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
9.6
30.6
63
67
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
30.1
521
3046
J01CA04
ATC
amoxicillin; systemic
1.7
29.9
1651
13576
M05BA04
ATC
alendronic acid; oral
2.8
29.9
207
786
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.7
29.8
759
5037
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
3.6
29.6
138
396
J20
ICD-10 Finland
Acute bronchitis
2.7
29.0
213
839
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
28.4
709
4662
A02BC01
ATC
omeprazole; systemic
1.8
28.4
665
4288
XG405
NOMESCO Finland
Education on PEF monitoring
10.8
28.0
54
51
J40
ICD-10 Finland
Bronchitis, not specified as acute or chronic
5.9
27.8
79
137
R03AL05
ATC
formoterol and aclidinium bromide; inhalant
146.6
27.7
29
*
R07.4
ICD-10 Finland
Chest pain, unspecified
1.8
27.2
631
4048
Z94.2
ICD-10 Finland
Lung transplant status
41.7
26.8
33
8
N02AA05
ATC
oxycodone; systemic
1.9
26.1
420
2377
49202
ICD-8 Finland
Emphysema, Focale (bullosum)
+∞
26.1
25
*
49201
ICD-8 Finland
Emphysema, Generale bronchitide non indicata
+∞
26.1
25
*
WX892
NOMESCO Finland
Monitored bed care
2.5
25.6
209
871
J98.2
ICD-10 Finland
Interstitial emphysema
136.4
25.6
27
*
TPH07
NOMESCO Finland
Cathetrisation of artery
2.2
25.6
284
1382
R05
ICPC
Cough
1.9
25.4
420
2401
GDG10
NOMESCO Finland
Bilateral transplantation of lung
50.5
25.3
30
6
R4110
NOMESCO Finland
Physiotherapy
1.7
25.2
599
3860
C34.12
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary adenocarcinoma
6.5
25.1
66
104
4912A
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS CHRONICA OBSTRUCTIVA]
+∞
25.0
24
*
WX721
NOMESCO Finland
Oxygen concentrator therapy
91.0
24.7
27
*
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
4.6
24.5
86
191
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.7
24.1
173
670
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.7
23.9
610
4002
N05BA04
ATC
oxazepam; oral
1.8
23.9
525
3295
A01AB09
ATC
miconazole; local oral
2.5
23.8
201
854
SPAT1257
SPAT
Teaching of medicine inhalation technique
4.3
23.7
90
216
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
4.5
23.6
85
194
R03DC01
ATC
zafirlukast; oral
14.0
23.6
40
29
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.3
23.5
227
1033
N06AX11
ATC
mirtazapine; oral
1.7
23.4
634
4226
XF600
NOMESCO Finland
Bloodpressure measurement
2.6
23.3
182
739
XG474
NOMESCO Finland
Exhalation nntrogen oxide
9.1
23.3
49
55
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.2
23.1
257
1250
4928A
ICD-9 Finland
Emphysema, Other emphysema[EMPHYSEMA SINE BRONCHITIDE]
+∞
22.9
22
*
J93.0
ICD-10 Finland
Spontaneous tension pneumothorax
30.3
22.8
30
10
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
2.7
22.7
166
651
R03BB02
ATC
oxitropium bromide; inhalant
13.2
22.4
39
30
I27.9
ICD-10 Finland
Pulmonary heart disease, unspecified
15.9
22.3
36
23
R06AE07
ATC
cetirizine; oral
1.6
22.1
722
5049
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.8
21.6
387
2262
J98.1
ICD-10 Finland
Pulmonary collapse
12.0
21.5
39
33
AN1
HP
Coronary angiography
1.9
21.5
360
2058
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.8
21.4
140
515
R29
ICPC
Respiratory symptom/complaint other
2.9
21.3
135
486
J01FA09
ATC
clarithromycin; systemic
1.7
21.1
547
3584
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.6
21.1
678
4709
J96.0
ICD-10 Finland
Acute respiratory failure
6.0
21.0
58
98
N03AX16
ATC
pregabalin; oral
1.7
20.9
487
3093
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
20.8
676
4704
R05CB01
ATC
acetylcysteine; inhalant, oral
5.4
20.6
62
117
J37.0
ICD-10 Finland
Chronic laryngitis
4.0
20.5
84
217
SPAT1058
SPAT
PEF monitoring instruction
2.6
20.2
155
626
XW5WT
NOMESCO Finland
Other blood specimen with radiologicl guidance
48.4
20.2
24
5
K05.31
ICD-10 Finland
Periodontitis pronounced
2.1
20.0
231
1138
I27.8
ICD-10 Finland
Other specified pulmonary heart diseases
27.3
20.0
27
10
XG404
NOMESCO Finland
Peak expiratory flow (PEF) measurement
23.6
19.9
28
12
F17.20
ICD-10 Finland
Addiction relationship caused by tobacco addiction relationship currently independent
16.5
19.6
31
19
A02BA02
ATC
ranitidine; systemic
1.7
19.6
484
3123
I71.4
ICD-10 Finland
Abdominal aortic aneurysm, without mention of rupture
2.9
19.4
124
449
A03
ICPC
Fever
2.0
19.2
253
1318
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
19.2
432
2709
UGC18
NOMESCO Finland
Flexible bronchoscopy with biopsy of lung
11.4
19.0
35
31
A02BC03
ATC
lansoprazole; oral
1.6
18.9
640
4481
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
18.8
608
4207
4931B
ICD-9 Finland
Asthma, Intrinsic asthma[INTRINSIC ASTHMA CUM EXACERBATIONE]
+∞
18.8
18
*
L04AA06
ATC
mycophenolic acid; systemic
5.5
18.7
55
101
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.2
18.7
189
878
5120A
ICD-9 Finland
Pneumothorax, Spontaneous tension pneumothorax
21.9
18.2
26
12
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
5.3
18.1
55
105
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
2.8
18.0
119
441
C01DA14
ATC
isosorbide mononitrate; oral
1.6
18.0
523
3516
4930A
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA SINE EXACERBATIONE]
+∞
17.7
17
*
N06AB04
ATC
citalopram; systemic
1.7
17.6
428
2739
C34.10
ICD-10 Finland
Malignant tumor of the upper lobe, bronchus or lung without histology
5.2
17.6
54
105
J01FF01
ATC
clindamycin; systemic
1.6
17.5
558
3840
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.5
17.4
654
4684
N05CD07
ATC
temazepam; oral
1.8
17.2
348
2105
C03DA01
ATC
spironolactone; oral
1.9
17.1
273
1529
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
6.1
16.9
46
77
A28
ICPC
Limited function/disability NOS
1.7
16.9
400
2539
49099
ICD-8 Finland
Bronchitis, unspecified
+∞
16.7
16
*
N06AA09
ATC
amitriptyline; systemic
2.0
16.6
211
1084
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.0
16.6
229
1216
N07BB01
ATC
disulfiram; oral
3.0
16.4
94
318
3039X
ICD-9 Finland
Alcohol dependence syndrome, Other and unspecified alcohol dependence
4.3
16.3
61
146
C34.11
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary epidermoid carcinoma
5.1
16.2
51
102
J61
ICD-10 Finland
Pneumoconiosis due to asbestos and other mineral fibres
7.4
16.2
38
52
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.8
16.1
291
1699
J01FA15
ATC
telithromycin; oral
2.2
16.0
176
850
J96.9
ICD-10 Finland
Respiratory failure, unspecified
11.7
16.0
29
25
XGX32
NOMESCO Finland
Bronchoscopic ultrasonography
6.8
16.0
40
60
P17
ICPC
Tobacco abuse
6.6
15.8
40
61
GDC00
NOMESCO Finland
Lobectomy of lung
7.3
15.7
37
51
GD2SN
NOMESCO Finland
Lung ventilation SPECT
8.8
15.7
33
38
4930B
ICD-9 Finland
Asthma, Extrinsic asthma[EXTRINSIC ASTHMA CUM EXACERBATIONE]
+∞
15.6
15
*
J92.9
ICD-10 Finland
Pleural plaque without asbestos
4.8
15.6
52
111
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.6
15.6
435
2882
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.8
15.6
288
1692
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.6
15.5
477
3235
XF400
NOMESCO Finland
ECG with 12 standard connections
1.6
15.4
423
2787
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.8
15.3
293
1740
N06AB10
ATC
escitalopram; oral
1.7
15.3
309
1868
N03AX12
ATC
gabapentin; oral
1.8
15.1
291
1729
H25.1
ICD-10 Finland
Senile nuclear cataract
1.5
15.1
666
4911
M81.9
ICD-10 Finland
Osteoporosis, unspecified
3.1
15.0
82
270
J10.0
ICD-10 Finland
Influenza with pneumonia, seasonal influenza virus identified
5.4
15.0
44
82
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.3
14.9
76
237
4859X
ICD-9 Finland
Bronchopneumonia, organism unspecified[PNEUMONIA NUD]
3.1
14.9
81
265
R05
ICD-10 Finland
Cough
1.7
14.9
342
2147
N06AX16
ATC
venlafaxine; oral
2.0
14.8
203
1071
JN4BD
NOMESCO Finland
Extensive body CT
1.8
14.8
268
1563
EBA15
NOMESCO Finland
Extraction of large number of teeth
2.6
14.6
109
432
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.4
14.6
787
6040
J18.0
ICD-10 Finland
Bronchopneumonia, unspecified
3.6
14.6
66
188
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.8
14.6
259
1502
Z51.5
ICD-10 Finland
Palliative care
2.1
14.5
176
884
GDC01
NOMESCO Finland
Thoracoscopic lobectomy of lung
6.3
14.3
37
59
N05AA02
ATC
levomepromazine; systemic
2.6
14.2
105
417
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
3.3
14.1
72
226
N05BA01
ATC
diazepam; systemic, rectal
1.7
14.0
288
1749
GDB11
NOMESCO Finland
Thoracoscopic wedge resection of lung
7.3
14.0
33
46
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.4
13.9
118
505
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
13.9
536
3832
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
1.7
13.8
334
2123
R03AK
ATC
Adrenergics in combination with corticosteroids or other drugs, excl. anticholinergics
53.6
13.8
16
*
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
3.8
13.8
57
151
R50.9
ICD-10 Finland
Fever, unspecified
1.7
13.8
302
1870
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.8
13.8
231
1315
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.4
13.7
866
6826
C01AA05
ATC
digoxin; systemic
1.7
13.7
274
1649
GD1UN
NOMESCO Finland
Lung circulation SPECT
8.6
13.7
29
34
I27.2
ICD-10 Finland
Other secondary pulmonary hypertension
10.5
13.7
26
25
SPAT1254
SPAT
Administration of medicine
1.7
13.6
316
1986
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.3
13.5
127
571
J41.1
ICD-10 Finland
Mucopurulent chronic bronchitis
34.2
13.5
17
5
J01DA01
ATC
[U] cefalexin; systemic
1.4
13.5
1275
10780
WX730
NOMESCO Finland
Conventional respirator
3.8
13.4
56
150
A06AD11
ATC
lactulose; oral
1.6
13.3
390
2608
R5140
NOMESCO Finland
Monitoring the use of the aid
1.8
13.3
218
1230
SPAT1060
SPAT
Administration of oxygen
8.6
13.2
28
33
8140/3-C34.1
ICD-O-3
Adenocarcinoma, NOS, of upper lobe, lung
6.9
13.1
32
47
B01AC04
ATC
clopidogrel; oral
1.5
13.1
431
2967
SPAT1263
SPAT
Sampling
1.4
13.0
819
6439
WX882
NOMESCO Finland
High dependency care
3.0
13.0
75
256
8070/3-C34.1
ICD-O-3
Squamous cell carcinoma, NOS, of upper lobe, lung
8.8
13.0
27
31
J13
ICD-10 Finland
Pneumonia due to Streptococcus pneumoniae
6.0
12.7
34
57
F10.24
ICD-10 Finland
Alcohol depence active use
5.4
12.7
37
69
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.5
12.7
510
3669
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.5
12.6
503
3611
GX2D5
NOMESCO Finland
Sleep oximetry
15.5
12.6
20
13
49109
ICD-8 Finland
Chronic bronchitis, Unspecified
+∞
12.5
12
*
GDB00
NOMESCO Finland
Resection of bullae of lung
+∞
12.5
12
*
GX1K5
NOMESCO Finland
Diffusion capacity
24.4
12.5
17
7
WX722
NOMESCO Finland
PEEP
2.3
12.4
112
496
N05AH04
ATC
quetiapine; oral
1.7
12.4
271
1676
R78
ICPC
Acute bronchitis/bronchiolitis
3.6
12.3
54
151
SPAT1309
SPAT
Guidance related to psychoactive substances / risk behaviour
3.9
12.3
50
131
GD5CD
NOMESCO Finland
Thorax and upper abdomen combined very extensive CT examination of
8.5
12.3
26
31
GDB01
NOMESCO Finland
Thoracoscopic resection of bullae of lung
37.7
12.2
15
*
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.4
12.1
598
4475
I20.99
ICD-10 Finland
Angina pectoris, unspecified
1.9
12.1
195
1093
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.7
12.1
278
1742
P01AB01
ATC
metronidazole; oral, rectal
1.4
12.1
687
5285
A02BC05
ATC
esomeprazole; systemic
1.4
12.1
764
5993
J41.0
ICD-10 Finland
Simple chronic bronchitis
18.1
12.0
18
10
127
Kela drug reimbursment
Transplant complication
4.4
12.0
42
96
J01DB01
ATC
cefalexin; oral
1.4
11.9
1643
14635
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.3
11.9
108
479
N02BE01
ATC
paracetamol; systemic, rectal
1.4
11.9
1802
16314
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.1
11.9
141
703
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.4
11.8
96
403
TGD00
NOMESCO Finland
Needle biopsy of lung
7.4
11.7
27
37
GX1E5
NOMESCO Finland
Flow volume spirometry and bronchodilation test
23.0
11.6
16
7
X59
ICD-10 Finland
Exposure to unspecified factor
1.6
11.5
340
2274
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
0.7
11.4
354
4922
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.9
11.4
180
1005
S22.3
ICD-10 Finland
Fracture of rib
2.0
11.3
144
740
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
11.3
631
4828
GX2C5
NOMESCO Finland
Short-lasting oximetry
35.2
11.3
14
*
R63.4
ICD-10 Finland
Abnormal weight loss
2.6
11.2
82
325
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.4
11.2
92
389
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.2
11.1
111
516
GD1BT
NOMESCO Finland
Biopsy of lung with X-ray guidance
25.1
11.1
15
6
R03BB05
ATC
aclidinium bromide; inhalant
25.1
11.1
15
6
GD2CT
NOMESCO Finland
Cytology of the lungs with CT guidance
25.1
11.1
15
6
G47.3
ICD-10 Finland
Sleep apnoea
1.5
11.1
377
2604
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
2.2
11.1
115
543
J86.9
ICD-10 Finland
Pyothorax without fistula
5.1
11.1
34
68
PD3YT
NOMESCO Finland
Pelvic artery PTA with stent
3.8
11.0
45
119
30320
ICD-8 Finland
Alcoholism, Alcoholic addiction
4.3
11.0
40
95
F32.1
ICD-10 Finland
Moderate depressive episode
3.0
11.0
63
215
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.8
11.0
184
1048
PD4BC
NOMESCO Finland
Extensive arterigography of lower extremity with X-ray
3.6
10.9
48
136
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.6
10.8
281
1819
I50
ICD-10 Finland
Heart failure
2.4
10.7
86
359
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
3.0
10.7
61
206
WZC30
NOMESCO Finland
Teaching
1.6
10.5
248
1567
I25.0
ICD-10 Finland
Atherosclerotic cardiovascular disease, so described
1.8
10.4
177
1012
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.7
10.4
198
1175
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
3.0
10.3
59
200
N06AA12
ATC
doxepin; systemic
2.1
10.3
114
552
R52.9
ICD-10 Finland
Pain, unspecified
1.9
10.3
152
828
PEF23
NOMESCO Finland
Thrombendarterectomy of femoral artery
3.0
10.3
59
202
8070/3-C34.3
ICD-O-3
Squamous cell carcinoma, NOS, of lower lobe, lung
9.6
10.2
20
21
TFB00
NOMESCO Finland
Cathetrisation of pulmonal artery
3.2
10.2
52
165
F10.25
ICD-10 Finland
Alcohol dependence continuous use
3.8
10.2
42
113
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.7
10.2
66
246
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
2.0
10.1
130
674
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.2
10.0
98
453
C34.19
ICD-10 Finland
Malignant tumor of the upper lobe, bronchus or lung other or unspecified histology
4.8
9.9
32
68
WW200
NOMESCO Finland
Immunization
2.9
9.9
58
202
N05AF03
ATC
chlorprothixene; systemic
3.1
9.9
52
169
284
Kela drug reimbursment
Nintedanib and pirfenidone
6.7
9.9
24
36
A31.0
ICD-10 Finland
Pulmonary mycobacterial infection
16.8
9.9
15
9
J85.1
ICD-10 Finland
Abscess of lung with pneumonia
16.8
9.9
15
9
R05FB02
ATC
cough suppressants and expectorants
1.4
9.8
760
6119
N05BA12
ATC
alprazolam; oral
1.7
9.7
183
1080
XG467
NOMESCO Finland
Nocturnal CO2 monitoring
55.2
9.6
11
*
N06AX21
ATC
duloxetine; oral
1.8
9.6
163
928
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.7
9.6
65
247
J01DA06
ATC
[U] cefuroxime; systemic
1.6
9.6
261
1708
L28
ICPC
Limited function/disability (L)
1.5
9.6
330
2282
AA1AD
NOMESCO Finland
CT of head and brain
1.4
9.5
522
3965
R03DA05
ATC
aminophylline; systemic, rectal
5.7
9.5
26
46
E0000UV
ATC
NA
1.4
9.5
689
5487
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.8
9.5
156
881
RS221
NOMESCO Finland
NA
4.1
9.4
35
86
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.1
9.4
103
499
49302
ICD-8 Finland
Asthma, Rhinitis allergica cum asthmate bronchiali
+∞
9.4
9
*
49101
ICD-8 Finland
Chronic bronchitis, Nonpurulenta (simplex)
+∞
9.4
9
*
3A006
NOMESCO Finland
NA
+∞
9.4
9
*
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
9.4
261
1717
C34.90
ICD-10 Finland
Malignant tumor in unspecified location in bronchus and lung without histology
3.9
9.3
37
97
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
3.1
9.3
48
155
A01AB04
ATC
amphotericin B; local oral
2.2
9.3
97
460
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.2
9.2
47
150
L04AD01
ATC
ciclosporin; systemic
3.5
9.1
41
119
XX3DW
NOMESCO Finland
Time consuming IT work
1.6
9.1
211
1324
C09AA05
ATC
ramipril; oral
1.4
9.1
599
4689
R07.3
ICD-10 Finland
Other chest pain
1.7
9.1
184
1110
R01AD09
ATC
mometasone; nasal
1.4
9.1
653
5185
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.1
9.1
94
447
J01FA10
ATC
azithromycin; systemic
1.3
9.1
872
7237
51299
ICD-8 Finland
Spontaneous pneumothorax
8.3
9.1
19
23
I70.9
ICD-10 Finland
Generalized and unspecified atherosclerosis
2.5
9.0
66
264
M05BA07
ATC
risedronic acid; oral
2.7
9.0
59
222
B01AF02
ATC
apixaban; oral
1.6
9.0
230
1478
R99
ICPC
Respiratory disease other
3.4
9.0
41
121
R79
ICPC
Chronic bronchitis
24.1
8.9
12
5
F10.20
ICD-10 Finland
Alcohol dependence currently independent
3.2
8.9
44
138
ZX108
NOMESCO Finland
Inhalation
5.5
8.9
25
46
R13
ICD-10 Finland
Dysphagia
1.9
8.9
135
746
30041
ICD-8 Finland
Neuroses, Depressiva
3.5
8.9
40
117
R51.80
ICD-10 Finland
Headache
1.7
8.8
195
1205
Z57.2
ICD-10 Finland
Occupational exposure to dust
8.6
8.8
18
21
R24
ICPC
Haemoptysis
5.9
8.7
23
39
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
1.8
8.7
137
762
I25.2
ICD-10 Finland
Old myocardial infarction
1.6
8.7
224
1443
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
1.9
8.7
135
748
WX250
NOMESCO Finland
Intercostal blockade
14.1
8.7
14
10
PD4DE
NOMESCO Finland
Lower extremity artery ultrasound examination with Doppler method
2.7
8.6
55
203
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
1.4
8.6
576
4514
M54.5
ICD-10 Finland
Low back pain
1.4
8.5
520
4012
B01AA03
ATC
warfarin; systemic
1.4
8.5
559
4369
XQ800
NOMESCO Finland
Prick test
2.3
8.5
74
323
D35.0
ICD-10 Finland
Benign neoplasm: Adrenal gland
3.2
8.5
42
132
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
2.4
8.5
66
274
I20.90
ICD-10 Finland
Angina pectoris, unspecified
2.0
8.5
105
536
F32
ICD-10 Finland
Depressive episode
2.4
8.4
66
275
R84
ICPC
Malignant neoplasm bronchus/lung
7.4
8.4
19
26
D07AB02
ATC
hydrocortisone butyrate; topical
1.4
8.4
496
3807
C34.31
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung epidermoid carcinoma
4.5
8.3
28
63
4900A
ICD-9 Finland
Bronchitis, not specified as acute or chronic[BRONCHITIS NUD]
+∞
8.3
8
*
4939A
ICD-9 Finland
Asthma, unspecified[ASTHMA ALIA DEFINITA SINE EXACERBATIONE]
+∞
8.3
8
*
4919X
ICD-9 Finland
Chronic bronchitis, Unspecified chronic bronchitis
+∞
8.3
8
*
J01GB01
ATC
tobramycin; inhalant, parenteral
+∞
8.3
8
*
4940A
ICD-9 Finland
Bronchiectasis[BRONCHIECTASIAE]
+∞
8.3
8
*
R01AD12
ATC
fluticasone furoate; nasal
1.4
8.3
365
2653
SPAT1260
SPAT
Consultation of another employee
1.5
8.3
327
2324
J01DA08
ATC
[U] cefaclor; oral
1.9
8.3
126
695
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.2
8.3
79
363
XF614
NOMESCO Finland
Measurement of pulmonary artery pressure
10.8
8.3
15
14
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
2.3
8.3
71
311
NE1AA
NOMESCO Finland
Pelvis X-ray examination
1.8
8.3
139
795
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.3
8.2
611
4864
B90.9
ICD-10 Finland
Sequelae of respiratory and unspecified tuberculosis
7.1
8.2
19
27
XJC10
NOMESCO Finland
Oesophageal pH monitoring
7.1
8.2
19
27
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.3
8.2
576
4545
C08DA01
ATC
verapamil; systemic
2.1
8.2
90
440
A02BA03
ATC
famotidine; systemic
2.0
8.2
97
490
R94.2
ICD-10 Finland
Abnormal results of pulmonary function studies
6.0
8.1
21
35
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
8.1
679
5500
F41.09
ICD-10 Finland
UNS Panic Syndrome
3.7
8.1
33
89
R53
ICD-10 Finland
Malaise and fatigue
1.4
8.1
396
2934
P01BA02
ATC
hydroxychloroquine; oral
1.8
8.1
137
783
J15.1
ICD-10 Finland
Pneumonia due to Pseudomonas
17.2
8.1
12
7
B44.1
ICD-10 Finland
Other pulmonary aspergillosis
17.2
8.1
12
7
R04.0
ICD-10 Finland
Epistaxis
1.7
8.0
168
1025
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
1.7
8.0
156
932
F10.30
ICD-10 Finland
Withdrawal symptoms caused by alcohol uncomplicated
4.1
8.0
29
71
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.7
8.0
147
866
XG499
NOMESCO Finland
Other fysiological examination of respiatory function
7.2
8.0
18
25
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
13.1
7.9
13
10
M34.9
ICD-10 Finland
Systemic sclerosis, unspecified
13.1
7.9
13
10
RK250
NOMESCO Finland
NA
7.8
7.9
17
22
SPE90
NOMESCO Finland
Other fitting and preparation of partial tooth prosthesis
2.6
7.8
54
209
DQB10
NOMESCO Finland
Endoscopic excision of lesion of larynx
3.9
7.8
30
77
N02AA01
ATC
morphine; systemic, rectal
2.7
7.8
50
185
PEH57
NOMESCO Finland
Bypass from femoral artery to popliteal artery below knee
3.7
7.8
32
87
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
1.8
7.8
135
779
F41.0
ICD-10 Finland
Panic disorder [episodic paroxysmal anxiety]
4.3
7.8
27
63
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.5
7.8
311
2219
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.1
7.8
80
381
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.6
7.8
197
1267
SPAT1104
SPAT
Monitoring of emergency patient
1.7
7.7
143
841
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
15.1
7.7
12
8
P76
ICPC
Depressive disorder
2.3
7.7
69
308
J12.8
ICD-10 Finland
Other viral pneumonia
5.3
7.7
22
42
L01CA04
ATC
vinorelbine; systemic
4.6
7.7
25
55
PDH54
NOMESCO Finland
Bypass from aorta to bilateral femoral arteries
7.4
7.7
17
23
N05AA01
ATC
chlorpromazine; systemic, rectal
3.5
7.7
33
94
F51.0
ICD-10 Finland
Nonorganic insomnia
1.7
7.6
166
1026
UJF32
NOMESCO Finland
Coloscopy
1.4
7.6
515
4033
GDB21
NOMESCO Finland
Thoracoscopic segmental resection of lung
18.4
7.6
11
6
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
1.9
7.6
109
592
EBA00
NOMESCO Finland
Extraction of tooth
1.3
7.6
560
4445
SPA00
NOMESCO Finland
Changing form of teeth in prepation for prothetic work
2.0
7.6
88
441
RS230
NOMESCO Finland
NA
6.7
7.6
18
27
SPD00
NOMESCO Finland
Fitting and preparation of total teeth prosthesis
3.6
7.5
32
90
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
1.8
7.5
125
709
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
2.0
7.5
92
470
A02BA04
ATC
nizatidine; systemic
1.6
7.5
171
1068
E66.2
ICD-10 Finland
Extreme obesity with alveolar hypoventilation
5.4
7.5
21
39
Z71.8
ICD-10 Finland
Other specified counselling
1.4
7.5
368
2728
PD5BD
NOMESCO Finland
Extensive CT of aorta
2.6
7.5
52
203
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
1.8
7.5
125
715
8140/3-C34.9
ICD-O-3
Adenocarcinoma, NOS, of lung, NOS
3.5
7.5
33
96
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.8
7.5
121
684
GCA98
NOMESCO Finland
Other bronchoscopic procedure on bronchus
4.4
7.4
25
57
PD4AC
NOMESCO Finland
Arterigography of lower extremity with X-ray
3.2
7.4
37
118
J18.1
ICD-10 Finland
Lobar pneumonia, unspecified
3.2
7.4
36
113
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.6
7.4
201
1318
EBA30
NOMESCO Finland
Excision of root of tooth
1.8
7.4
115
643
Z02.7
ICD-10 Finland
Issue of medical certificate
1.9
7.4
109
598
D07AC01
ATC
betamethasone; topical
1.3
7.3
643
5233
R01
ICPC
Pain respiratory system
3.8
7.3
29
77
G44.2
ICD-10 Finland
Tension-type headache
1.6
7.3
169
1058
ZX120
NOMESCO Finland
Intravenous
1.6
7.3
183
1172
A15.0
ICD-10 Finland
Tuberculosis of lung, confirmed by sputum microscopy with or without culture
8.4
7.3
15
18
PD4CG
NOMESCO Finland
Extensive MRI examination of abdominal aortta and vasculature of lower extremities with high intensity magnet
3.0
7.3
39
131
F34.1
ICD-10 Finland
Dysthymia
2.6
7.3
49
190
D44.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Adrenal gland
3.9
7.2
28
73
D07BA04
ATC
hydrocortisone and antiseptics; topical
1.6
7.2
165
1032
RK110
NOMESCO Finland
NA
4.6
7.2
23
50
N05AC02
ATC
thioridazine; oral
3.0
7.2
38
127
SPAT1057
SPAT
Peak expiratory flow measurement
3.3
7.2
34
105
GAC40
NOMESCO Finland
Pleurodesis with decortication
30.1
7.1
9
*
J93
ICD-10 Finland
Pneumothorax
30.1
7.1
9
*
GAC47
NOMESCO Finland
Endoscopic partial decortication of pleura
20.1
7.1
10
5
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
1.7
7.1
146
889
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.0
7.1
82
410
WX402
NOMESCO Finland
General anaesthesia
1.5
7.1
264
1857
M79.6
ICD-10 Finland
Pain in limb
1.3
7.1
578
4654
201
Kela drug reimbursment
Chronic cardiac insufficiency
1.7
7.1
155
959
FB1AD
NOMESCO Finland
CT examination of arteria pulmonalis
5.6
7.1
19
34
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
3.8
7.0
28
75
H05AA02
ATC
teriparatide; parenteral
8.8
7.0
14
16
N06AX12
ATC
bupropion; oral
2.3
7.0
64
287
D19
ICPC
Teeth/gum symptom/complaint
0.7
7.0
204
2890
R03DA54
ATC
theophylline, combinations excl. psycholeptics; systemic
3.0
7.0
37
124
E000001
ATC
NA
1.4
7.0
340
2518
C34.32
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung adenocarcinoma
4.0
7.0
26
66
I48.9
ICD-10 Finland
Atrial fibrillation and atrial flutter, unspecified
1.8
6.9
122
710
S72.0
ICD-10 Finland
Fracture of neck of femur
1.9
6.9
103
565
A04
ICPC
Weakness/tiredness general
1.5
6.9
228
1563
J18
ICD-10 Finland
Pneumonia, organism unspecified
4.2
6.9
24
57
J38.1
ICD-10 Finland
Polyp of vocal cord and larynx
4.6
6.9
22
48
A02BX05
ATC
bismuth subcitrate; oral
2.8
6.9
42
154
F10.2
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Dependence syndrome
3.5
6.9
30
87
W19
ICD-10 Finland
Unspecified fall
1.6
6.9
180
1167
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
3.6
6.9
29
82
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
3.0
6.9
36
120
B99
ICD-10 Finland
Other and unspecified infectious diseases
2.4
6.8
52
215
D38.0
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Larynx
4.8
6.8
21
44
L57.0
ICD-10 Finland
Actinic keratosis
0.6
6.8
97
1599
318
Kela drug reimbursment
Teriparatide
8.3
6.8
14
17
ZXA10
NOMESCO Finland
Bilateral
1.4
6.8
347
2589
E88.9
ICD-10 Finland
Metabolic disorder, unspecified
40.1
6.8
8
*
J41.8
ICD-10 Finland
Mixed simple and mucopurulent chronic bronchitis
40.1
6.8
8
*
F10.09
ICD-10 Finland
Alcohol intoxication UNS
2.8
6.8
41
150
356
Kela drug reimbursment
Nintedanib and pirfenidone
5.7
6.7
18
32
R50
ICPC
Respiratory, Medication/prescr/renewal
16.7
6.7
10
6
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
2.9
6.7
39
137
I65.2
ICD-10 Finland
Occlusion and stenosis of carotid artery
2.2
6.7
66
310
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.5
6.7
262
1858
J15.8
ICD-10 Finland
Other bacterial pneumonia
4.3
6.7
23
54
ZPB22
NOMESCO Finland
Autograft of vein
4.3
6.7
23
54
M03BC01
ATC
orphenadrine (citrate); systemic
1.4
6.7
324
2397
M80.5
ICD-10 Finland
Idiopathic osteoporosis with pathological fracture
6.4
6.6
16
25
N17.9
ICD-10 Finland
Acute renal failure, unspecified
1.9
6.6
93
502
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
1.8
6.6
101
562
H02AB09
ATC
hydrocortisone; systemic
2.9
6.6
38
132
N06AX03
ATC
mianserin; oral
1.9
6.6
91
489
C34.99
ICD-10 Finland
Malignant tumor in unspecified localization in bronchial and pulmonary other or unspecified histology
3.4
6.6
29
85
WX872
NOMESCO Finland
Intensive care
1.8
6.6
106
599
N06AB03
ATC
fluoxetine; oral
1.6
6.6
186
1230
4660A
ICD-9 Finland
Acute bronchitis and bronchiolitis, Acute bronchitis
4.0
6.6
24
60
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
1.8
6.5
111
641
R52.2
ICD-10 Finland
Other chronic pain
2.4
6.5
53
228
SPAT1212
SPAT
Extensive examination of musculoskeletal system
1.7
6.5
133
808
N06AB06
ATC
sertraline; oral
1.7
6.5
140
866
R60.0
ICD-10 Finland
Localized oedema
1.5
6.5
207
1407
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.4
6.5
408
3156
A03FA01
ATC
metoclopramide; systemic, rectal
1.4
6.5
379
2896
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
2.0
6.5
75
377
XX1XW
NOMESCO Finland
Extensive written report from radiologist
2.6
6.5
44
173
SPAT1255
SPAT
Intravenous administration of medicine
1.7
6.5
123
735
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
1.9
6.4
83
433
M05BX04
ATC
denosumab; parenteral
1.9
6.4
85
451
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.4
6.4
279
2025
DQA10
NOMESCO Finland
Biopsy of larynx
4.9
6.3
19
39
SPAT1301
SPAT
No procedures
1.3
6.3
601
4929
5BA08
NOMESCO Finland
NA
6.6
6.3
15
23
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
1.9
6.3
82
429
L04AX01
ATC
azathioprine; systemic
2.0
6.3
74
375
F17.2
ICD-10 Finland
Mental and behavioural disorders due to use of tobacco, dependence syndrome
5.5
6.3
17
31
XX4BW
NOMESCO Finland
NA
9.3
6.3
12
13
F20.9
ICD-10 Finland
Schizophrenia, unspecified
2.8
6.3
37
133
G30.1
ICD-10 Finland
Alzheimer disease with late onset
0.5
6.3
61
1110
5AB14
NOMESCO Finland
NA
18.0
6.3
9
5
49200
ICD-8 Finland
NA
+∞
6.2
6
*
4939B
ICD-9 Finland
Asthma, unspecified[ASTHMA ALIA DEFINITA CUM EXACERBATIONE]
+∞
6.2
6
*
C34.9
ICD-10 Finland
Malignant neoplasm: Bronchus or lung, unspecified
2.9
6.2
34
117
B37.09
ICD-10 Finland
Unspecified candidal stomatitis
4.3
6.2
21
49
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
2.0
6.2
69
342
A01AB10
ATC
natamycin; local oral
2.2
6.2
56
252
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
1.7
6.2
122
737
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
0.5
6.2
49
945
T74.1
ICD-10 Finland
Physical abuse
3.9
6.2
23
59
UDQ22
NOMESCO Finland
Microlaryngoscopy
3.6
6.2
25
69
ZXA05
NOMESCO Finland
Left side
1.3
6.2
509
4095
S01ED51
ATC
timolol, combinations; ophthalmic
0.6
6.1
69
1206
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.4
6.1
271
1972
SAA04
NOMESCO Finland
Special inverstigation of mouth
1.9
6.1
79
414
OAA67
SPAT
NA
0.3
6.1
13
420
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
1.7
6.1
131
808
E66.00
ICD-10 Finland
Metabolic syndrome
1.9
6.1
83
445
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
3.5
6.1
26
75
H04.10
ICD-10 Finland
Dry eye syndrome
1.6
6.1
142
898
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
2.5
6.0
43
171
J93.8
ICD-10 Finland
Other pneumothorax
4.9
6.0
18
37
JN3AD
NOMESCO Finland
Abdominal CT examination
1.6
6.0
148
947
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
6.7
6.0
14
21
R85
ICPC
Malignant neopl respiratory other
10.0
6.0
11
11
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.7
6.0
115
686
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
1.8
6.0
92
514
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.6
6.0
160
1043
Mortality – FinRegistry
↥Association
Association between endpoint J10_EMPHYSEMA and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_EMPHYSEMA | 3.684 [3.14, 4.33] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.009 |
During the follow-up period (1.1.1998 — 31.12.2019), 1167 out of 3260 females with J10_EMPHYSEMA died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_EMPHYSEMA | 3.237 [2.81, 3.72] | < 0.001 |
| Birth year | 0.985 [0.98, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 3606 out of 7590 males with J10_EMPHYSEMA died.
Mortality risk
Mortality risk for people of age
years, who have J10_EMPHYSEMA.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.307% | 0.643% |
| 5 | 1.856% | 3.69% |
| 10 | 4.444% | 8.79% |
| 15 | 8.028% | 16.011% |
| 20 | 13.584% | 25.898% |
Relationships between endpoints
↥Index endpoint: J10_EMPHYSEMA – Emphysema
GWS hits: 2
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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