No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2804 |
4. Check minimum number of eventsNone |
2804 |
5. Include endpointsNone |
2804 |
6. Filter based on genotype QC (FinnGen only) |
2804 |
Control definitions (FinnGen only)
- Control exclude
- J10_PLEURA
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- J90-J94
- Name in latin
- Pneumothorax
Similar endpoints
↥List of similar endpoints to
Pneumothorax
based on the number of shared cases.
Similar with more cases:
- Other diseases of pleura
- Diseases of the respiratory system
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 22531 | 5868 | 16399 |
| Only index persons | 17810 | 4882 | 12928 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.38 | 0.17 | 0.46 |
| Only index persons | 0.41 | 0.18 | 0.49 |
| Median age at first event (years) | |||
| Whole population | 50.37 | 56.14 | 48.09 |
| Only index persons | 43.39 | 52.37 | 40.00 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2804 | 806 | 1998 |
| Unadjusted period prevalence (%) | 0.71 | 0.27 | 0.88 |
| Median age at first event (years) | 57.75 | 51.42 | 60.30 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2504
- Matched controls
- 25041
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
J93.1
ICD-10 Finland
Other spontaneous pneumothorax
16384.0
323.0
1061
*
J93.8
ICD-10 Finland
Other pneumothorax
+∞
323.0
545
*
51299
ICD-8 Finland
Spontaneous pneumothorax
+∞
323.0
321
*
GAA10
NOMESCO Finland
Intercostal insertion of pleural drainage tube
85.2
323.0
584
89
J93.9
ICD-10 Finland
Pneumothorax, unspecified
7388.3
323.0
584
*
J93.0
ICD-10 Finland
Spontaneous tension pneumothorax
+∞
300.2
282
*
5120A
ICD-9 Finland
Pneumothorax, Spontaneous tension pneumothorax
+∞
287.1
270
*
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
447.7
209.7
207
5
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.4
177.1
768
2271
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
5.6
171.2
566
1246
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
4.8
163.8
627
1617
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
5.3
141.6
481
1072
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.9
136.5
1368
7356
GD1AD
NOMESCO Finland
Thorax CT examination
8.0
135.5
326
457
UGC12
NOMESCO Finland
Flexible bronchoscopy
5.5
130.3
425
897
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
7.2
129.7
338
533
J96.1
ICD-10 Finland
Chronic respiratory failure
+∞
119.7
114
*
R03BB04
ATC
tiotropium bromide; inhalant
4.2
112.2
487
1369
GD1CT
NOMESCO Finland
Biopsy of the lung with CT guidance
16.7
102.8
168
107
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.7
95.9
880
4209
GDB01
NOMESCO Finland
Thoracoscopic resection of bullae of lung
+∞
90.1
86
*
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
5.7
89.8
276
531
GAC47
NOMESCO Finland
Endoscopic partial decortication of pleura
290.9
83.1
84
*
D38.1
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Trachea, bronchus and lung
7.3
83.0
210
311
J94.8
ICD-10 Finland
Other specified pleural conditions
813.7
80.9
79
*
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
7.1
79.5
204
308
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
4.5
64.9
246
590
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
5.4
64.2
204
404
C34.12
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary adenocarcinoma
12.5
64.2
118
99
R06.0
ICD-10 Finland
Dyspnoea
2.3
62.1
694
3524
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.5
60.9
595
2820
J93
ICD-10 Finland
Pneumothorax
315.1
60.6
61
*
130
Kela drug reimbursment
Malignant tumour
3.2
59.7
346
1188
S27.0
ICD-10 Finland
Traumatic pneumothorax
14.4
58.7
101
73
J43.9
ICD-10 Finland
Emphysema, unspecified
8.8
56.5
125
149
H02AB06
ATC
prednisolone; systemic
2.0
54.9
1182
7846
TGA30
NOMESCO Finland
Thoracocentesis
59.6
54.7
64
11
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
7.1
54.7
139
206
GDC01
NOMESCO Finland
Thoracoscopic lobectomy of lung
14.1
52.0
90
66
GDB11
NOMESCO Finland
Thoracoscopic wedge resection of lung
25.0
51.7
73
30
R03AC02
ATC
salbutamol; inhalant
1.9
50.7
1216
8307
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.5
50.6
254
777
R4110
NOMESCO Finland
Physiotherapy
2.1
50.0
713
3979
8140/3-C34.1
ICD-O-3
Adenocarcinoma, NOS, of upper lobe, lung
19.3
49.0
75
40
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.5
47.5
411
1798
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.9
46.7
202
545
5841
FHL
Trocar rhostomy
102.0
45.9
50
5
N02AA05
ATC
oxycodone; systemic
2.4
44.5
442
2073
J92.0
ICD-10 Finland
Pleural plaque with presence of asbestos
83.3
44.0
49
6
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.3
43.7
494
2463
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.7
41.8
322
1313
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
6.5
41.6
111
176
JN4BD
NOMESCO Finland
Extensive body CT
2.5
40.5
350
1522
ZXD05
NOMESCO Finland
Urgent procedure
1.9
40.4
813
5098
J96.0
ICD-10 Finland
Acute respiratory failure
142.3
39.8
42
*
R03DA04
ATC
theophylline; systemic, rectal
3.1
39.7
232
791
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
39.2
563
3100
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
39.0
687
4097
J01MA14
ATC
moxifloxacin; systemic
2.8
38.8
277
1076
J01MA12
ATC
levofloxacin; systemic
2.1
38.5
542
2959
Z51.5
ICD-10 Finland
Palliative care
3.2
38.1
214
708
WX892
NOMESCO Finland
Monitored bed care
2.9
37.9
251
931
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
7.3
35.9
88
124
R03AK03
ATC
[D] fenoterol & other drugs for obstructive airway dis; inhalant
2.9
35.8
234
859
H02AB02
ATC
dexamethasone; systemic
2.6
35.1
276
1134
R95
ICPC
Chron obstructive pulmonary disease
4.8
34.9
120
259
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
5.1
34.4
113
232
R03AC12
ATC
salmeterol; inhalant
3.4
34.4
173
528
R03AL06
ATC
olodaterol and tiotropium bromide; inhalant
6.7
33.9
88
135
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
6.4
33.6
90
144
TPH07
NOMESCO Finland
Cathetrisation of artery
2.4
32.5
297
1320
XG410
NOMESCO Finland
Flow-volume spirometry
3.8
32.4
141
382
GAA96
NOMESCO Finland
Other open or percutaneous drainage of pleural cavity
29.1
32.0
43
15
N02AX02
ATC
tramadol; systemic, rectal
1.7
31.6
1028
7350
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
8.4
31.0
69
84
5822
FHL
Exploratory thoracotomy and small procedure (eg lung suture)
42.8
30.9
38
9
A03FA01
ATC
metoclopramide; systemic, rectal
2.0
30.2
475
2680
5128X
ICD-9 Finland
Pneumothorax, Other spontaneous pneumothorax
+∞
29.2
28
*
GAC34
NOMESCO Finland
Endoscopic mechanical pleurodesis
+∞
29.2
28
*
J86.9
ICD-10 Finland
Pyothorax without fistula
9.3
29.2
61
67
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
29.0
460
2598
GAC37
NOMESCO Finland
Endoscopic chemical pleurodesis
295.2
28.8
29
*
A02BC02
ATC
pantoprazole; systemic
1.6
28.6
1457
11617
TGC00
NOMESCO Finland
Bronchial lavation
4.9
28.6
95
198
Z3231
NOMESCO Finland
Registered nurse
1.8
28.6
671
4327
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
3.0
28.6
173
601
R03BB01
ATC
ipratropium bromide; inhalant
3.2
28.5
161
534
GDC00
NOMESCO Finland
Lobectomy of lung
10.4
27.5
54
53
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
16.0
27.2
44
28
Z2221
NOMESCO Finland
Medical doctor
1.7
27.1
635
4079
GDB00
NOMESCO Finland
Resection of bullae of lung
+∞
27.1
26
*
L01CA04
ATC
vinorelbine; systemic
11.3
27.1
51
46
JN4AD
NOMESCO Finland
Body CT examination
2.5
27.0
219
912
Z3226
NOMESCO Finland
Physiotherapist
1.9
26.7
451
2598
A04AA01
ATC
ondansetron; systemic, rectal
2.9
26.6
174
638
J45.9
ICD-10 Finland
Asthma, unspecified
2.0
26.4
403
2233
R02
ICPC
Shortness of breath/dyspnoea
2.2
25.8
292
1432
N03AX16
ATC
pregabalin; oral
1.8
25.8
521
3187
GAA31
NOMESCO Finland
Thoracoscopy
18.8
25.7
39
21
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
10.0
25.5
51
52
J45.1
ICD-10 Finland
Nonallergic asthma
2.7
25.2
180
694
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
3.2
25.1
136
439
J98.1
ICD-10 Finland
Pulmonary collapse
58.6
25.0
29
5
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
25.0
838
5934
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
5.2
24.9
78
153
WF049
NOMESCO Finland
Radiotherapy of metastasis
3.5
24.4
117
344
J44
ICD-10 Finland
Other chronic obstructive pulmonary disease
4.5
24.1
88
203
R03AK07
ATC
formoterol and budesonide; inhalant
1.9
23.5
413
2402
WF004
NOMESCO Finland
Palliative radiotherapy
4.7
23.4
80
173
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
10.6
23.3
45
43
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
4.9
23.2
77
161
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
22.8
629
4206
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
22.7
1079
8269
GDA21
NOMESCO Finland
Thoracoscopic excision of lesion of lung
45.4
22.4
27
6
H02AB07
ATC
prednisone; oral
1.9
22.2
347
1933
C34.32
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung adenocarcinoma
7.0
22.2
55
80
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.4
22.2
191
820
C34.10
ICD-10 Finland
Malignant tumor of the upper lobe, bronchus or lung without histology
6.0
22.1
61
103
WX250
NOMESCO Finland
Intercostal blockade
29.3
21.9
29
10
GDA11
NOMESCO Finland
Thoracoscopic biopsy of lung
22.4
21.7
31
14
R03AK04
ATC
salbutamol and sodium cromoglicate; inhalant
7.2
21.1
51
72
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
5.0
20.6
67
138
N80.89
ICD-10 Finland
Endometriosis with other specified or multiple localization
30.3
20.6
27
9
WZC30
NOMESCO Finland
Teaching
1.9
20.5
315
1743
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
3.8
20.4
87
233
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.8
20.4
387
2301
Z94.2
ICD-10 Finland
Lung transplant status
32.8
20.2
26
8
GDG10
NOMESCO Finland
Bilateral transplantation of lung
48.4
20.2
24
5
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.7
20.2
437
2713
C34.82
ICD-10 Finland
Malignant overall tumor of bronchial and pulmonary adenocarcinoma
10.4
19.6
38
37
ZX120
NOMESCO Finland
Intravenous
2.1
19.3
233
1170
Z2446
NOMESCO Finland
Social worker
2.4
19.3
169
730
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
2.7
19.3
138
535
C34.92
ICD-10 Finland
Malignant tumor in unspecified localization in bronchial and pulmonary adenocarcinoma
31.5
19.3
25
8
GDB21
NOMESCO Finland
Thoracoscopic segmental resection of lung
22.7
19.1
27
12
J96.9
ICD-10 Finland
Respiratory failure, unspecified
55.4
18.9
22
*
GAC00
NOMESCO Finland
Biopsy of pleura
100.8
18.6
20
*
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
3.2
18.4
100
325
N02BE01
ATC
paracetamol; systemic, rectal
1.5
18.4
1918
17051
WX402
NOMESCO Finland
General anaesthesia
1.8
18.4
342
2017
GAC46
NOMESCO Finland
Partial decortication of pleura
44.3
18.2
22
5
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.4
18.1
154
657
XQ858
NOMESCO Finland
Oxygen partial pressure measurement
8.4
17.9
39
47
GDB10
NOMESCO Finland
Wedge resection of lung
18.2
17.8
27
15
GAC97
NOMESCO Finland
Other endoscopic operation on pleura
20.2
17.7
26
13
GAC40
NOMESCO Finland
Pleurodesis with decortication
+∞
17.7
17
*
J94.2
ICD-10 Finland
Haemothorax
181.2
17.5
18
*
GAC36
NOMESCO Finland
Chemical pleurodesis
181.2
17.5
18
*
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.7
17.5
383
2374
C45.0
ICD-10 Finland
Mesothelioma of pleura
42.3
17.3
21
5
J45.8
ICD-10 Finland
Mixed asthma
3.3
17.2
86
263
C34.11
ICD-10 Finland
Malignant tumor of the anterior, bronchial or pulmonary epidermoid carcinoma
5.5
17.2
51
95
R03AL02
ATC
salbutamol and ipratropium bromide; inhalant
6.6
17.2
44
68
348
Kela drug reimbursment
Roflumilast
25.8
16.9
23
9
ZXE00
NOMESCO Finland
One hour or less
1.5
16.9
838
6362
R03AC13
ATC
formoterol; inhalant
2.6
16.8
127
508
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.3
16.6
152
674
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
16.5
626
4477
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.6
16.1
116
452
C34.31
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung epidermoid carcinoma
6.4
16.1
42
67
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
3.1
16.0
87
284
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.8
15.8
266
1517
N05CF01
ATC
zopiclone; oral
1.5
15.7
711
5274
R03BA01
ATC
beclometasone; inhalant
1.8
15.7
306
1827
A04AA02
ATC
granisetron; systemic, transdermal
2.4
15.6
132
564
J84.8
ICD-10 Finland
Other specified interstitial pulmonary diseases
5.7
15.5
44
78
J94.9
ICD-10 Finland
Pleural condition, unspecified
160.9
15.5
16
*
J01AA02
ATC
doxycycline; systemic
1.4
15.5
1713
15059
R28
ICPC
Limited function/disability (R)
5.2
15.3
47
92
XG466
NOMESCO Finland
Sleep oxymetry
3.1
15.1
86
288
S22.4
ICD-10 Finland
Multiple fractures of ribs
3.4
14.9
72
216
R52.0
ICD-10 Finland
Acute pain
3.1
14.8
80
261
GAB10
NOMESCO Finland
Antero- or postero-lateral thoracotomy
9.2
14.7
30
33
M05BA04
ATC
alendronic acid; oral
2.2
14.6
159
763
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
14.5
572
4106
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
2.7
14.4
101
387
C78.2
ICD-10 Finland
Secondary malignant neoplasm of pleura
27.3
14.3
19
7
R81
ICPC
Pneumonia
2.8
14.2
92
337
R03DX07
ATC
roflumilast; oral
22.4
14.2
20
9
J43.8
ICD-10 Finland
Other emphysema
14.5
14.0
23
16
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.2
14.0
145
681
C34.30
ICD-10 Finland
Malignant tumor of the lower lobe, bronchus or lung without histology
6.1
13.9
37
61
XX3DW
NOMESCO Finland
Time consuming IT work
1.9
13.8
224
1256
C34.1
ICD-10 Finland
Malignant neoplasm: Upper lobe, bronchus or lung
3.5
13.8
64
187
UGC18
NOMESCO Finland
Flexible bronchoscopy with biopsy of lung
8.6
13.7
29
34
ZXE20
NOMESCO Finland
More than three and less than five hours
1.7
13.6
323
2041
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.5
13.6
658
4922
GD1BT
NOMESCO Finland
Biopsy of lung with X-ray guidance
75.5
13.6
15
*
J98.2
ICD-10 Finland
Interstitial emphysema
+∞
13.5
13
*
ZXD10
NOMESCO Finland
Scheduled procedure
1.4
13.5
806
6278
C03CA01
ATC
furosemide; systemic
1.4
13.2
685
5188
R03BA05
ATC
fluticasone; inhalant
1.6
13.2
343
2222
R03AC18
ATC
indacaterol; inhalant
6.1
13.2
35
58
ZXA05
NOMESCO Finland
Left side
1.5
13.2
553
4014
R04.2
ICD-10 Finland
Haemoptysis
2.5
13.1
100
403
JN4CD
NOMESCO Finland
Very extensive body CT
2.5
13.0
104
432
GD1BA
NOMESCO Finland
Extensive X-ray examination of thorax
5.4
13.0
38
71
R03AL08
ATC
vilanterol, umeclidinium bromide and fluticasone furoate; inhalant
4.5
12.9
45
102
R03BA02
ATC
budesonide; inhalant
1.6
12.8
345
2253
R03AC03
ATC
terbutaline; inhalant
1.7
12.8
270
1648
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
3.9
12.7
52
137
8140/3-C34.9
ICD-O-3
Adenocarcinoma, NOS, of lung, NOS
5.8
12.7
35
61
ZXA00
NOMESCO Finland
Right side
1.5
12.6
587
4346
J43.1
ICD-10 Finland
Panlobular emphysema
70.2
12.6
14
*
J92.9
ICD-10 Finland
Pleural plaque without asbestos
70.2
12.6
14
*
R4190
NOMESCO Finland
Nutritional therapy
3.0
12.6
73
251
GAC41
NOMESCO Finland
Endoscopic pleurodesis with decortication
+∞
12.5
12
*
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.5
12.5
100
416
R84
ICPC
Malignant neoplasm bronchus/lung
9.3
12.5
25
27
1503
FHL
Thoracoscopy and other therapeutic procedure
130.6
12.4
13
*
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.3
12.3
118
537
8070/3-C34.3
ICD-O-3
Squamous cell carcinoma, NOS, of lower lobe, lung
8.5
12.3
26
31
WX872
NOMESCO Finland
Intensive care
2.2
12.2
126
594
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
12.1
383
2600
XX1XW
NOMESCO Finland
Extensive written report from radiologist
3.4
12.1
58
174
L04AA06
ATC
mycophenolic acid; systemic
4.0
12.1
48
123
8140/3-C34.3
ICD-O-3
Adenocarcinoma, NOS, of lower lobe, lung
8.7
12.0
25
29
A28
ICPC
Limited function/disability NOS
1.6
12.0
332
2182
S22.3
ICD-10 Finland
Fracture of rib
2.0
12.0
161
844
C07AB07
ATC
bisoprolol; oral
1.4
11.9
1053
8726
N07BA03
ATC
varenicline; oral
2.3
11.8
110
493
YG1BD
NOMESCO Finland
Extensive CT examination of thorax for dose design of radiotherapy
3.0
11.8
67
226
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.1
11.7
125
598
R03AK08
ATC
formoterol and beclometasone; inhalant
2.7
11.7
77
287
GD5CD
NOMESCO Finland
Thorax and upper abdomen combined very extensive CT examination of
7.7
11.6
26
34
RS221
NOMESCO Finland
NA
4.2
11.6
43
104
GAC01
NOMESCO Finland
Endoscopic biopsy of pleura
65.2
11.6
13
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.7
11.6
276
1745
Z31.5
ICD-10 Finland
Genetic counselling
2.6
11.3
83
331
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
2.2
11.2
111
513
B01AB05
ATC
enoxaparin; parenteral
1.4
10.9
611
4671
J01CA04
ATC
amoxicillin; systemic
1.3
10.8
1698
15267
J01FA06
ATC
roxithromycin; oral
1.4
10.8
800
6414
ZXE40
NOMESCO Finland
More than seven and less than nine hours
2.9
10.8
63
219
XF600
NOMESCO Finland
Bloodpressure measurement
1.9
10.8
146
771
N06AX11
ATC
mirtazapine; oral
1.4
10.7
602
4603
XGX32
NOMESCO Finland
Bronchoscopic ultrasonography
5.3
10.6
31
59
AA1AD
NOMESCO Finland
CT of head and brain
1.4
10.5
511
3796
J43.2
ICD-10 Finland
Centrilobular emphysema
11.2
10.5
19
17
N02AA01
ATC
morphine; systemic, rectal
3.8
10.4
43
116
A10BA02
ATC
metformin; oral
0.7
10.3
343
4723
ZX109
NOMESCO Finland
Instruction on medicine inhalation technique
5.8
10.3
28
49
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
23.4
10.2
14
6
A06AD11
ATC
lactulose; oral
1.5
10.2
336
2302
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
5.0
10.2
31
62
R13
ICD-10 Finland
Dysphagia
1.9
10.1
143
768
WX110
NOMESCO Finland
Local anesthesy
1.3
10.1
1374
12035
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.1
10.0
110
534
ZX108
NOMESCO Finland
Inhalation
6.5
10.0
25
39
WX002
NOMESCO Finland
Sedation and analgesia
1.5
9.9
403
2888
WX725
NOMESCO Finland
Noninvasive ventilation
2.3
9.9
89
395
191
Kela drug reimbursment
Erlotinib
16.8
9.9
15
9
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.6
9.8
237
1505
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.9
9.8
152
844
C34.90
ICD-10 Finland
Malignant tumor in unspecified location in bronchus and lung without histology
3.7
9.7
41
113
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
3.3
9.6
46
140
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.9
9.6
144
787
N80.3
ICD-10 Finland
Endometriosis of pelvic peritoneum
4.1
9.4
35
86
9050/3-C38.4
ICD-O-3
Mesothelioma, malignant of pleura, NOS
100.4
9.4
10
*
5862
FHL
Decortication (removal of visceral or parietal pleura)
30.1
9.4
12
*
5119X
ICD-9 Finland
Pleurisy, Unspecified pleural effusion
+∞
9.4
9
*
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
2.1
9.4
106
523
L03AA02
ATC
filgrastim; parenteral
2.7
9.2
59
219
WX882
NOMESCO Finland
High dependency care
2.5
9.0
66
265
J47
ICD-10 Finland
Bronchiectasis
3.2
9.0
44
137
TGD00
NOMESCO Finland
Needle biopsy of lung
6.5
8.9
22
34
JN3BD
NOMESCO Finland
Extensive abdominal CT
1.6
8.9
220
1401
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
2.9
8.9
51
176
127
Kela drug reimbursment
Transplant complication
3.5
8.8
39
112
WF002
NOMESCO Finland
Radical radiotherapy
1.9
8.7
126
683
R05CB01
ATC
acetylcysteine; inhalant, oral
2.9
8.7
50
172
9052/3-C38.4
ICD-O-3
Epithelioid mesothelioma, malignant of pleura, NOS
50.1
8.7
10
*
TPX10
NOMESCO Finland
Implantation of vascular injection port
2.5
8.5
66
273
A31.0
ICD-10 Finland
Pulmonary mycobacterial infection
9.0
8.5
17
19
103
Kela drug reimbursment
Diabetes, insulin-treated
0.7
8.5
347
4636
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.4
8.5
68
285
1BA04
NOMESCO Finland
NA
20.1
8.5
12
6
JN5DR
NOMESCO Finland
PET-CT of upper body metabolism
3.3
8.5
41
127
I26.9
ICD-10 Finland
Pulmonary embolism without mention of acute cor pulmonale
1.9
8.4
111
584
GAC33
NOMESCO Finland
Mechanical pleurodesis
+∞
8.3
8
*
R11
ICD-10 Finland
Nausea and vomiting
1.8
8.3
143
823
4912B
ICD-9 Finland
Chronic bronchitis, Obstructive chronic bronchitis[BRONCHITIS OBSTRUCTIVA CUM EMPHYSEMATE]
3.3
8.3
40
124
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.6
8.2
205
1314
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
3.1
8.2
42
136
A01AB09
ATC
miconazole; local oral
1.7
8.1
162
973
R03BA08
ATC
ciclesonide; inhalant
1.8
8.1
141
811
JCF12
NOMESCO Finland
Endoscopic insertion of prosthetic tube into oesphagus
5.7
8.1
22
39
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
2.0
8.1
94
470
WW200
NOMESCO Finland
Immunization
2.5
8.0
59
237
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
1.7
8.0
151
895
WW500
NOMESCO Finland
Blood transfusion
2.1
8.0
84
403
S27.2
ICD-10 Finland
Traumatic haemopneumothorax
13.1
7.9
13
10
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
2.2
7.8
77
359
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
0.5
7.7
68
1277
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
0.6
7.7
105
1754
A07AA02
ATC
nystatin; oral
1.8
7.7
117
647
A02BC01
ATC
omeprazole; systemic
1.3
7.7
557
4409
N17.9
ICD-10 Finland
Acute renal failure, unspecified
2.0
7.6
90
454
I71.4
ICD-10 Finland
Abdominal aortic aneurysm, without mention of rupture
2.1
7.6
79
379
8070/3-C34.1
ICD-O-3
Squamous cell carcinoma, NOS, of upper lobe, lung
5.7
7.5
20
35
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
7.4
637
5166
5869
FHL
Other measure in this category
80.3
7.4
8
*
J91
ICD-10 Finland
Pleural effusion in conditions classified elsewhere
80.3
7.4
8
*
GAC43
NOMESCO Finland
Total decortication of pleura
80.3
7.4
8
*
WZC20
NOMESCO Finland
Multidisciplinary treatment meeting
1.9
7.4
101
537
GD2CT
NOMESCO Finland
Cytology of the lungs with CT guidance
13.4
7.4
12
9
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
1.9
7.4
109
599
B01AB10
ATC
tinzaparin; parenteral
1.8
7.3
125
716
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
2.5
7.3
54
218
JC2AB
NOMESCO Finland
Oesophagus X-ray examination with contrast
3.9
7.2
28
73
R50.9
ICD-10 Finland
Fever, unspecified
1.5
7.2
281
1993
XW5WT
NOMESCO Finland
Other blood specimen with radiologicl guidance
15.8
7.2
11
7
J80
ICD-10 Finland
Adult respiratory distress syndrome
7.3
7.2
16
22
155
Kela drug reimbursment
Afatinib and gefitinib
30.1
7.1
9
*
JDB10
NOMESCO Finland
Percutaneous gastrostomy
3.2
7.0
35
112
M05BX04
ATC
denosumab; parenteral
2.0
7.0
82
413
J02AC03
ATC
voriconazole; systemic
10.0
7.0
13
13
N05BA04
ATC
oxazepam; oral
1.4
7.0
456
3542
N80.9
ICD-10 Finland
Endometriosis, unspecified
4.3
7.0
24
56
R09.1
ICD-10 Finland
Pleurisy
3.2
7.0
34
107
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
3.0
7.0
37
124
WD325
NOMESCO Finland
Demanding therapy of methastized malignancy with biomodifiers
3.8
7.0
27
71
X57
ICD-10 Finland
Unspecified privation
2.4
6.9
53
221
GDA20
NOMESCO Finland
Excision of lesion of lung
7.5
6.9
15
20
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.3
6.9
872
7429
XF614
NOMESCO Finland
Measurement of pulmonary artery pressure
13.8
6.9
11
8
JAH00
NOMESCO Finland
Laparotomy
2.3
6.9
58
252
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.4
6.9
428
3303
H02AB04
ATC
methylprednisolone; systemic
1.5
6.9
260
1835
ZY010
NOMESCO Finland
Hospital outpatient
2.0
6.9
82
414
C79.30
ICD-10 Finland
Secondary malignant tumor of the cerebrum
3.7
6.9
28
77
J01MA02
ATC
ciprofloxacin; systemic
1.3
6.8
825
6985
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
1.7
6.8
151
937
XG460
NOMESCO Finland
Short time oxymetry
2.6
6.8
45
173
YG1CD
NOMESCO Finland
Very extensive CT examination of thorax for dose design of radiotherapy
5.0
6.8
20
40
N80
ICD-10 Finland
Endometriosis
9.3
6.8
13
14
WX600
NOMESCO Finland
Single shot through catheter
3.3
6.8
32
99
L01EB04
ATC
osimertinib; oral
40.1
6.8
8
*
341
Kela drug reimbursment
Afatinib and gefitinib
40.1
6.8
8
*
3004
Kela drug reimbursment
Osimertinib
40.1
6.8
8
*
RS220
NOMESCO Finland
NA
3.3
6.7
31
94
P01AB01
ATC
metronidazole; oral, rectal
1.3
6.7
681
5637
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
1.9
6.7
88
464
J15.8
ICD-10 Finland
Other bacterial pneumonia
4.1
6.7
24
59
WX730
NOMESCO Finland
Conventional respirator
2.8
6.7
40
145
M17.1
ICD-10 Finland
Other primary gonarthrosis
0.7
6.6
214
2983
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
2.1
6.6
72
353
RS230
NOMESCO Finland
NA
5.2
6.6
19
37
R03AL03
ATC
vilanterol and umeclidinium bromide; inhalant
3.2
6.6
32
101
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
4.0
6.6
24
60
R05CB03
ATC
carbocisteine; oral
2.3
6.6
54
234
I50.9
ICD-10 Finland
Heart failure, unspecified
1.4
6.5
303
2222
C34.3
ICD-10 Finland
Malignant neoplasm: Lower lobe, bronchus or lung
2.8
6.5
38
135
A06AH03
ATC
naloxegol; oral
3.6
6.5
27
76
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
2.9
6.4
35
120
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
2.1
6.4
68
329
3A006
NOMESCO Finland
NA
70.0
6.4
7
*
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
1.6
6.4
147
921
C34.9
ICD-10 Finland
Malignant neoplasm: Bronchus or lung, unspecified
3.2
6.4
31
98
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
1.8
6.3
98
546
J17.3*B59
ICD-10 Finland
Pneumonia due to Pneumocystis carinii
6.6
6.3
15
23
WX722
NOMESCO Finland
PEEP
1.8
6.3
100
562
J01DB01
ATC
cefalexin; oral
1.3
6.3
1739
16131
TKC20
NOMESCO Finland
Catheterisation of bladder
1.6
6.3
162
1048
J01FF01
ATC
clindamycin; systemic
1.3
6.3
519
4172
Z72.0
ICD-10 Finland
Tobacco use
2.3
6.3
52
226
M48.5
ICD-10 Finland
Collapsed vertebra, not elsewhere classified
9.3
6.3
12
13
A02BC05
ATC
esomeprazole; systemic
1.3
6.3
752
6351
AK3
HP
BLTX (both lung transplants)
+∞
6.2
6
*
E42
ICD-10 Finland
Marasmic kwashiorkor
26.7
6.2
8
*
5823
FHL
Lung avobiopsy and wedge resection
26.7
6.2
8
*
R03BB07
ATC
umeclidinium bromide; inhalant
4.3
6.2
21
49
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
1.6
6.2
142
892
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.3
6.1
478
3811
XX4BW
NOMESCO Finland
NA
7.7
6.1
13
17
ZX090
NOMESCO Finland
Other technic of radiotherapy
2.2
6.1
58
267
D01
ICPC
Abdominal pain/cramps general
1.6
6.1
161
1047
TK800
NOMESCO Finland
Hemodialysis
2.3
6.1
50
216
J86.00
ICD-10 Finland
Empyema with broncho-pleural fistula
12.5
6.1
10
8
WX726
NOMESCO Finland
High-flow oxygen therapy
12.5
6.1
10
8
R03BB02
ATC
oxitropium bromide; inhalant
3.6
6.1
25
70
M03BC01
ATC
orphenadrine (citrate); systemic
1.3
6.0
379
2924
WW200
SPAT
NA
0.6
6.0
70
1210
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
1.9
6.0
86
469
Mortality – FinRegistry
↥Association
Association between endpoint J10_PNEUMOTHORAX and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_PNEUMOTHORAX | 3.635 [3.02, 4.38] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.272 |
During the follow-up period (1.1.1998 — 31.12.2019), 1318 out of 3535 females with J10_PNEUMOTHORAX died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| J10_PNEUMOTHORAX | 3.073 [2.67, 3.54] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.011 |
During the follow-up period (1.1.1998 — 31.12.2019), 3115 out of 8847 males with J10_PNEUMOTHORAX died.
Mortality risk
Mortality risk for people of age
years, who have J10_PNEUMOTHORAX.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.378% | 0.728% |
| 5 | 2.178% | 3.226% |
| 10 | 5.309% | 8.486% |
| 15 | 9.927% | 15.785% |
| 20 | 16.779% | 25.869% |
Relationships between endpoints
↥Index endpoint: J10_PNEUMOTHORAX – Pneumothorax
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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