No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1313 |
4. Check minimum number of eventsNone |
1313 |
5. Include endpointsNone |
1313 |
6. Filter based on genotype QC (FinnGen only) |
1313 |
Control definitions (FinnGen only)
- Control exclude
- K11_OESSTODUO
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- K22
- Name in latin
- Obstructio oesophagi
Similar endpoints
↥List of similar endpoints to
Oesophageal obstruction
based on the number of shared cases.
Similar with more cases:
- Diseases of oesophagus, stomach and duodenum
- Gastrointestinal diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 10378 | 4277 | 5966 |
| Only index persons | 7927 | 3308 | 4619 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.15 | 0.12 | 0.17 |
| Only index persons | 0.15 | 0.12 | 0.18 |
| Median age at first event (years) | |||
| Whole population | 67.37 | 70.35 | 65.19 |
| Only index persons | 66.11 | 68.96 | 64.07 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1313 | 510 | 803 |
| Unadjusted period prevalence (%) | 0.28 | 0.17 | 0.35 |
| Median age at first event (years) | 66.20 | 65.03 | 66.94 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1187
- Matched controls
- 11871
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K22.2
ICD-10 Finland
Oesophageal obstruction
4503599627370496.0
323.0
1155
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
38.7
323.0
954
1135
JCA55
NOMESCO Finland
Endoscopic dilatation of oesophagus
1013.9
323.0
486
8
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
87.5
323.0
378
63
R13
ICD-10 Finland
Dysphagia
32.2
323.0
489
252
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
64.2
183.3
212
40
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
18.3
172.5
279
196
UJC12
NOMESCO Finland
Flexible oesophagoscopy
115.7
157.8
169
17
T18.1
ICD-10 Finland
Foreign body in oesophagus
118.7
153.5
164
16
K22.1
ICD-10 Finland
Ulcer of oesophagus
1608.0
148.1
141
*
JC2AB
NOMESCO Finland
Oesophagus X-ray examination with contrast
86.9
143.6
159
21
UJD02
NOMESCO Finland
Gastroscopy
21.7
143.5
216
120
JCF12
NOMESCO Finland
Endoscopic insertion of prosthetic tube into oesphagus
91.7
131.7
145
18
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
21.6
129.5
195
107
A02BC05
ATC
esomeprazole; systemic
4.1
110.2
651
2720
A02BC02
ATC
pantoprazole; systemic
4.3
105.8
931
5441
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
27.4
93.6
130
53
K22.0
ICD-10 Finland
Achalasia of cardia
+∞
90.8
86
*
UJC02
NOMESCO Finland
Rigid oesophagoscopy
71.0
86.0
98
15
K20
ICD-10 Finland
Oesophagitis
78.8
78.4
88
12
C15.5
ICD-10 Finland
Malignant neoplasm: Lower third of oesophagus
42.1
77.7
97
25
JCA08
NOMESCO Finland
Endoscopic removal of foreign body from oesophagus
211.2
77.2
79
*
K22.4
ICD-10 Finland
Dyskinesia of oesophagus
684.6
66.6
65
*
JBC01
NOMESCO Finland
Laparoscopic gastro-oesophageal antireflux operation
651.1
63.4
62
*
A02BC03
ATC
lansoprazole; oral
3.1
61.6
444
1910
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
24.1
55.2
79
35
5303A
ICD-9 Finland
Diseases of oesophagus, Stricture and stenosis of oesophagus[STRICTURA ET STENOSIS OESOPHAGI]
+∞
54.6
52
*
K22.7
ICD-10 Finland
Barrett oesophagus
113.0
50.2
54
5
JDB10
NOMESCO Finland
Percutaneous gastrostomy
17.5
49.7
79
48
JDA55
NOMESCO Finland
Endoscopic dilatation of stomach, pylorus or anastomosis of stomach
173.7
48.2
50
*
K22.9
ICD-10 Finland
Disease of oesophagus, unspecified
166.4
46.1
48
*
C15.9
ICD-10 Finland
Malignant neoplasm: Oesophagus, unspecified
56.4
45.9
54
10
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.0
44.8
318
1304
K22.8
ICD-10 Finland
Other specified diseases of oesophagus
442.9
43.5
43
*
A02BC01
ATC
omeprazole; systemic
2.6
43.0
399
1917
ZXD05
NOMESCO Finland
Urgent procedure
2.5
42.5
461
2413
K22.3
ICD-10 Finland
Perforation of oesophagus
+∞
41.9
40
*
WX408
NOMESCO Finland
General anesthesy, balanced
2.6
41.8
405
1989
A02BA02
ATC
ranitidine; systemic
2.9
41.2
304
1269
R11
ICD-10 Finland
Nausea and vomiting
4.6
39.5
146
349
A03FA01
ATC
metoclopramide; systemic, rectal
2.8
39.5
316
1380
K92.0
ICD-10 Finland
Haematemesis
12.5
38.5
70
59
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.2
37.2
603
3766
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.4
36.2
411
2161
TJD20
NOMESCO Finland
Change of gastrostomy tube
36.7
36.1
46
13
JCC12
NOMESCO Finland
Thoracoscopic or laparoscopic partial oesophagectomy
44.5
35.2
43
10
R4190
NOMESCO Finland
Nutritional therapy
7.8
34.6
82
112
1323
FHL
Esophagoscopy and dilatation
+∞
33.5
32
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.7
32.8
266
1154
TPH04
NOMESCO Finland
Cathetrisation of vein
2.5
31.6
311
1499
C15.4
ICD-10 Finland
Malignant neoplasm: Middle third of oesophagus
43.5
31.0
38
9
K29.3
ICD-10 Finland
Chronic superficial gastritis
52.9
30.5
36
7
WX002
NOMESCO Finland
Sedation and analgesia
2.5
30.4
293
1393
UJF32
NOMESCO Finland
Coloscopy
2.3
30.4
332
1685
K22.5
ICD-10 Finland
Diverticulum of oesophagus, acquired
+∞
29.3
28
*
K23.8*B37.8
ICD-10 Finland
Esophagitis caused by candidiasis
+∞
29.3
28
*
W44
ICD-10 Finland
Foreign body entering into or through eye or natural orifice
9.8
28.9
59
63
JN4BD
NOMESCO Finland
Extensive body CT
2.9
28.3
196
768
JCA98
NOMESCO Finland
Other local endoscopic operation on oesophagus
287.8
27.9
28
*
N02AA05
ATC
oxycodone; systemic
2.5
27.8
243
1092
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
3.8
27.5
122
344
D21
ICPC
Swallowing problem
9.9
26.6
54
57
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
3.8
26.5
118
333
A07AA02
ATC
nystatin; oral
3.7
25.4
118
345
UJC01
NOMESCO Finland
Scopy of lower throat
12.6
24.7
44
36
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.3
24.5
259
1276
JCC10
NOMESCO Finland
Transthoracic partial oesophagectomy without interposition
57.2
24.1
28
5
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.9
24.1
102
276
UGC12
NOMESCO Finland
Flexible bronchoscopy
3.0
23.9
147
530
A02BC04
ATC
rabeprazole; oral
3.8
23.7
104
290
130
Kela drug reimbursment
Malignant tumour
2.8
23.4
166
655
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
5.1
23.4
76
158
K29.7
ICD-10 Finland
Gastritis, unspecified
13.9
22.8
39
29
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
5.7
22.8
67
124
8070/3-C15.9
ICD-O-3
Squamous cell carcinoma, NOS, of esophagus, NOS
23.4
22.6
32
14
WX402
NOMESCO Finland
General anaesthesia
2.4
22.5
216
1010
K25.9
ICD-10 Finland
Gastric ulcer, Unspecified as acute or chronic, without haemorrhage or perforation
45.9
22.4
27
6
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.0
22.2
355
2079
1320
FHL
Esophagoscopy
24.4
22.2
31
13
N06AX11
ATC
mirtazapine; oral
2.0
22.2
367
2178
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
29.7
21.9
29
10
D84
ICPC
Oesophagus disease
63.7
21.9
25
*
A03FA02
ATC
cisapride; oral, rectal
3.2
21.7
122
412
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.6
21.4
100
294
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
9.3
21.2
44
49
XJC02
NOMESCO Finland
Mesurement of oesophageal pressure and pressure profile of lower oesophageal sphincter
51.0
21.2
25
5
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.3
21.2
231
1145
53091
ICD-8 Finland
Diseases of oesophagus, Strictura
+∞
20.9
20
*
J01MA12
ATC
levofloxacin; systemic
2.1
20.7
269
1442
N05CF01
ATC
zopiclone; oral
1.9
20.6
409
2582
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
3.8
20.3
90
253
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.8
20.3
141
548
N03AX16
ATC
pregabalin; oral
2.1
19.9
279
1541
C15.3
ICD-10 Finland
Malignant neoplasm: Upper third of oesophagus
58.5
19.9
23
*
6241
FHL
Fund application (Nissen)
+∞
19.8
19
*
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
19.7
253
1347
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
3.3
19.7
104
337
X59
ICD-10 Finland
Exposure to unspecified factor
2.2
19.1
226
1161
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.6
19.0
149
620
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
4.0
18.9
78
206
WX302
NOMESCO Finland
Thoracal epidural anesthesy
3.4
18.5
91
279
GD5BD
NOMESCO Finland
Thorax and upper abdomen combined extensive CT examination of
5.3
18.2
56
110
ZXE00
NOMESCO Finland
One hour or less
1.8
18.1
464
3160
K25.0
ICD-10 Finland
Gastric ulcer, Acute with haemorrhage
+∞
17.7
17
*
XJC00
NOMESCO Finland
Oesophageal manometry
+∞
17.7
17
*
5301A
ICD-9 Finland
Diseases of oesophagus, Oesophagitis[OESOPHAGITIS REFLUENS]
+∞
17.7
17
*
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.6
17.5
82
242
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
10.9
17.5
33
31
J38.0
ICD-10 Finland
Paralysis of vocal cords and larynx
7.4
17.3
41
57
GD1AD
NOMESCO Finland
Thorax CT examination
3.8
17.2
74
204
K30
ICD-10 Finland
Functional dyspepsia
3.4
17.1
86
268
Z43.1
ICD-10 Finland
Attention to gastrostomy
50.7
17.0
20
*
RD210
NOMESCO Finland
NA
8.8
17.0
36
42
K92.1
ICD-10 Finland
Melaena
3.7
17.0
75
211
JCE21
NOMESCO Finland
Laparoscopic cardiomyotomy
+∞
16.7
16
*
JDD00
NOMESCO Finland
Total gastrectomy and Roux-en-Y oesophagojejunostomy
35.6
16.7
21
6
A02BA04
ATC
nizatidine; systemic
2.8
16.7
110
414
K25.3
ICD-10 Finland
Gastric ulcer, Acute without haemorrhage or perforation
172.2
16.5
17
*
JDB00
NOMESCO Finland
Gastrostomy
28.0
16.5
22
8
A04AA01
ATC
ondansetron; systemic, rectal
3.0
16.0
97
346
GBB00
NOMESCO Finland
Tracheostomy
8.2
15.8
35
44
8140/3-C15.9
ICD-O-3
Adenocarcinoma, NOS, of esophagus, NOS
60.8
15.8
18
*
R4110
NOMESCO Finland
Physiotherapy
1.8
15.8
321
2009
ZXD10
NOMESCO Finland
Scheduled procedure
1.7
15.7
449
3120
UJF30
NOMESCO Finland
Ileoscopy through colon
2.7
15.6
108
419
B03BA03
ATC
hydroxocobalamin; parenteral
3.0
15.4
90
313
H02AB06
ATC
prednisolone; systemic
1.7
15.0
526
3858
ZXE40
NOMESCO Finland
More than seven and less than nine hours
4.9
15.0
49
104
R53
ICD-10 Finland
Malaise and fatigue
1.9
14.8
236
1353
D13.0
ICD-10 Finland
Benign neoplasm: Oesophagus
25.4
14.7
20
8
K29.4
ICD-10 Finland
Chronic atrophic gastritis
21.3
14.7
21
10
T28.6
ICD-10 Finland
Corrosion of oesophagus
+∞
14.6
14
*
TJF00
NOMESCO Finland
Insertion of jejunal tube
81.1
14.6
16
*
JBC00
NOMESCO Finland
Gastro-oesophageal antireflux operation
81.1
14.6
16
*
K29.8
ICD-10 Finland
Duodenitis
151.7
14.5
15
*
JFF00
NOMESCO Finland
Catheter enterostomy
151.7
14.5
15
*
JD1EE
NOMESCO Finland
Ultrasound examination of gastro-oesophageal reflux
27.5
14.3
19
7
D64.9
ICD-10 Finland
Anaemia, unspecified
2.3
14.2
134
614
Z98.8
ICD-10 Finland
Other specified postsurgical states
7.2
13.9
33
47
SPAT1254
SPAT
Administration of medicine
2.0
13.8
191
1035
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.7
13.8
366
2471
J01DB01
ATC
cefalexin; oral
1.7
13.7
881
7507
T36
ICD-10 Finland
Poisoning by systemic antibiotics
4.2
13.7
52
129
JCC00
NOMESCO Finland
Transhiatal partial oesophagectomy without interposition
+∞
13.6
13
*
EN1BD
NOMESCO Finland
Very extensive CT examination of mouth and soft tissues of neck
5.7
13.5
38
68
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
5.0
13.5
43
89
Z51.5
ICD-10 Finland
Palliative care
2.6
13.5
98
391
T05
ICPC
Feeding problem of adult
16.4
13.5
21
13
F10.25
ICD-10 Finland
Alcohol dependence continuous use
6.8
13.3
33
50
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.7
13.3
376
2575
N02AX02
ATC
tramadol; systemic, rectal
1.6
13.2
483
3542
GBB13
NOMESCO Finland
Revision of tracheostomy
40.5
13.2
16
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.7
13.0
355
2405
J45.9
ICD-10 Finland
Asthma, unspecified
1.9
12.9
193
1078
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.1
12.8
150
758
JN4CD
NOMESCO Finland
Very extensive body CT
3.0
12.8
73
250
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.9
12.7
77
273
C15.1
ICD-10 Finland
Malignant neoplasm: Thoracic part of oesophagus
70.6
12.6
14
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.4
12.5
110
485
C16.00
ICD-10 Finland
Cardia
17.5
12.5
19
11
K29.0
ICD-10 Finland
Acute haemorrhagic gastritis
+∞
12.5
12
*
JCC30
NOMESCO Finland
Transthoracic partial oesophagectomy with interposition of intestine
+∞
12.5
12
*
K22.6
ICD-10 Finland
Gastro-oesophageal laceration-haemorrhage syndrome
+∞
12.5
12
*
K26.0
ICD-10 Finland
Duodenal ulcer, acute with haemorrhage
+∞
12.5
12
*
P01AB01
ATC
metronidazole; oral, rectal
1.6
12.5
381
2656
Z3226
NOMESCO Finland
Physiotherapist
1.8
12.4
220
1300
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.8
12.3
219
1298
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
12.2
208
1213
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.1
12.1
149
768
WB121
NOMESCO Finland
Demanding neoadjuvant cytostatic therapy
7.0
12.1
29
42
8140/3-C16.0
ICD-O-3
Adenocarcinoma, NOS, of cardia, NOS
27.0
12.1
16
6
JAH00
NOMESCO Finland
Laparotomy
3.8
11.7
49
133
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.2
11.7
125
607
A06AC01
ATC
ispaghula (psylla seeds); oral
1.7
11.6
254
1608
R06.0
ICD-10 Finland
Dyspnoea
1.7
11.6
283
1847
XG410
NOMESCO Finland
Flow-volume spirometry
3.3
11.6
57
177
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
5.3
11.5
34
65
Z2221
NOMESCO Finland
Medical doctor
1.7
11.5
294
1943
K26.9
ICD-10 Finland
Duodenal ulcer, unspecified as acute or chronic, without haemorrhage or perforation
+∞
11.5
11
*
JCF00
NOMESCO Finland
Insertion of prosthetic tube into oesphagus
+∞
11.5
11
*
JCA96
NOMESCO Finland
Other local operation on oesophagus
+∞
11.5
11
*
5308A
ICD-9 Finland
Diseases of oesophagus, Other specified disorders of oesophagus[HERNIA HIATUS OESOPHAGI (""""SLIDING HERNIA"""")]
+∞
11.5
11
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.0
11.5
152
808
H02AB02
ATC
dexamethasone; systemic
2.1
11.3
128
637
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
9.0
11.3
23
26
C15.0
ICD-10 Finland
Malignant neoplasm: Cervical part of oesophagus
35.4
11.3
14
*
RD160
NOMESCO Finland
NA
35.4
11.3
14
*
J02AC01
ATC
fluconazole; systemic
1.6
11.2
335
2307
A06AD11
ATC
lactulose; oral
1.9
11.2
188
1088
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
5.1
11.1
34
68
A02BDXX
ATC
NA
3.7
11.1
48
135
WX600
NOMESCO Finland
Single shot through catheter
6.0
10.9
29
49
D37.7
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Other digestive organs
3.9
10.8
43
112
X58
ICD-10 Finland
Exposure to other specified factors
2.0
10.8
147
787
ZXE10
NOMESCO Finland
More than one and less than three hours
1.6
10.8
407
2970
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.0
10.8
145
776
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
5.9
10.8
29
50
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.4
10.7
94
416
J01MA02
ATC
ciprofloxacin; systemic
1.5
10.7
444
3310
A28
ICPC
Limited function/disability NOS
1.8
10.7
199
1194
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.8
10.6
67
247
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
4.1
10.6
40
100
K21
ICD-10 Finland
Gastro-oesophageal reflux disease
3.7
10.5
45
126
R03BB04
ATC
tiotropium bromide; inhalant
2.0
10.4
135
711
R03AC02
ATC
salbutamol; inhalant
1.5
10.4
514
3981
JCA45
NOMESCO Finland
Endoscopic mucosal or submucosal resection in oesophagus
110.9
10.4
11
*
C15.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of oesophagus
110.9
10.4
11
*
K25.7
ICD-10 Finland
Gastric ulcer, Chronic without haemorrhage or perforation
110.9
10.4
11
*
A02BX02
ATC
sucralfate; oral
3.1
10.4
57
192
N07BB01
ATC
disulfiram; oral
3.2
10.3
54
176
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
2.0
10.3
145
788
SPAT1125
SPAT
Stoma care and guidance
4.2
10.3
38
93
UGB02
NOMESCO Finland
Tracheoscopy
23.6
10.2
14
6
N05CD07
ATC
temazepam; oral
1.9
10.2
164
936
JN3AD
NOMESCO Finland
Abdominal CT examination
2.3
10.1
95
435
R07.4
ICD-10 Finland
Chest pain, unspecified
1.6
10.1
286
1934
H02AB07
ATC
prednisone; oral
1.9
10.0
158
897
L28
ICPC
Limited function/disability (L)
1.8
9.9
192
1164
DQE00
NOMESCO Finland
Implantation of prosthetic replacement for larynx
26.2
9.8
13
5
K29.1
ICD-10 Finland
Other acute gastritis
20.2
9.8
14
7
R12
ICD-10 Finland
Heartburn
2.7
9.8
66
254
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.0
9.6
134
723
A01AB09
ATC
miconazole; local oral
2.1
9.6
105
513
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.3
9.5
86
387
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.8
9.4
158
911
K29.9
ICD-10 Finland
Gastroduodenitis, unspecified
30.2
9.4
12
*
53094
ICD-8 Finland
Diseases of oesophagus, Oesophagitis
+∞
9.4
9
*
WZC30
NOMESCO Finland
Teaching
1.8
9.3
154
887
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.6
9.3
66
262
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.2
9.3
96
460
WX892
NOMESCO Finland
Monitored bed care
2.1
9.0
101
499
XJC10
NOMESCO Finland
Oesophageal pH monitoring
37.0
9.0
11
*
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
2.6
9.0
64
253
WX110
NOMESCO Finland
Local anesthesy
1.5
9.0
674
5630
JBB01
NOMESCO Finland
Laparoscopic repair of paraoesophageal hernia
18.7
8.9
13
7
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
2.5
8.9
68
281
R51.80
ICD-10 Finland
Headache
2.0
8.9
117
617
C16.09
ICD-10 Finland
Malignant tumor of cardiac or other unspecified carcinoma
24.2
8.9
12
5
UDH02
NOMESCO Finland
Rhinopharyngoscopy
2.5
8.9
68
282
107
Kela drug reimbursment
Pernicious anaemia
4.1
8.9
33
82
EBA15
NOMESCO Finland
Extraction of large number of teeth
2.8
8.9
56
207
GA1AE
NOMESCO Finland
Ultrasound examination of thorax
3.9
8.9
35
92
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
8.8
457
3542
N05BA04
ATC
oxazepam; oral
1.6
8.8
243
1628
B81
ICPC
Anaemia vit B12/folate deficiency
3.0
8.7
50
173
J01FF01
ATC
clindamycin; systemic
1.6
8.7
276
1913
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
3.6
8.7
38
109
JDA32
NOMESCO Finland
Endoscopic injection in stomach or pylorus
50.3
8.7
10
*
K22
ICD-10 Finland
Other diseases of oesophagus
50.3
8.7
10
*
Z93.1
ICD-10 Finland
Gastrostomy status
50.3
8.7
10
*
ZX120
NOMESCO Finland
Intravenous
2.0
8.6
107
554
K59.09
ICD-10 Finland
Constipation, unspecified
2.3
8.5
74
327
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.1
8.5
94
465
JF1AD
NOMESCO Finland
Small bowel CT
27.7
8.5
11
*
GBB96
NOMESCO Finland
Other tracheostomy procedure
90.6
8.4
9
*
K26.3
ICD-10 Finland
Duodenal ulcer, acute without haemorrhage or perforation
90.6
8.4
9
*
JCB00
NOMESCO Finland
Oesophagostomy
90.6
8.4
9
*
K26.7
ICD-10 Finland
Duodenal ulcer, chronic without haemorrhage or perforation
90.6
8.4
9
*
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.2
8.4
81
377
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.9
8.4
121
666
ZXE20
NOMESCO Finland
More than three and less than five hours
1.7
8.3
164
997
JCE00
NOMESCO Finland
Suture of oesophagus
+∞
8.3
8
*
JCA32
NOMESCO Finland
Endoscopic injection in oesophagus
+∞
8.3
8
*
K31.8
ICD-10 Finland
Other specified diseases of stomach and duodenum
+∞
8.3
8
*
JCD03
NOMESCO Finland
Subcutaneous anastomosis of oesophagus with interposition of intestine
+∞
8.3
8
*
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.7
8.3
56
214
A02BD07
ATC
lansoprazole, amoxicillin and clarithromycin; systemic
2.9
8.3
49
175
K44
ICD-10 Finland
Diaphragmatic hernia
9.5
8.3
16
17
N05AH04
ATC
quetiapine; oral
1.8
8.3
145
850
Z3231
NOMESCO Finland
Registered nurse
1.5
8.2
297
2120
1310
FHL
Esophagogastroscopy
14.6
8.2
13
9
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.3
8.2
77
354
N05BA02
ATC
chlordiazepoxide; systemic
3.8
8.2
33
89
C16.9
ICD-10 Finland
Malignant neoplasm: Stomach, unspecified
8.2
8.1
17
21
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.7
8.1
33
90
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.4
8.1
65
277
SPAT1263
SPAT
Sampling
1.4
8.0
439
3419
ZZQ00
NOMESCO Finland
Free microvascular graft of skin
10.1
8.0
15
15
N05BA01
ATC
diazepam; systemic, rectal
1.8
8.0
146
865
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
5.0
7.9
24
49
ZXE01
NOMESCO Finland
Procedure duration 0 to 9 minutes
5.0
7.9
24
49
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
6.6
7.9
19
29
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
5.4
7.8
22
41
F10.24
ICD-10 Finland
Alcohol depence active use
5.8
7.8
21
37
F10.09
ICD-10 Finland
Alcohol intoxication UNS
4.5
7.8
26
59
J01MA14
ATC
moxifloxacin; systemic
2.0
7.7
98
510
B01AB05
ATC
enoxaparin; parenteral
1.5
7.7
337
2504
W79
ICD-10 Finland
Inhalation and ingestion of food causing obstruction of respiratory tract
15.1
7.7
12
8
K25.4
ICD-10 Finland
Gastric ulcer, Chronic or unspecified with haemorrhage
45.2
7.7
9
*
K08.3
ICD-10 Finland
Retained dental root
2.1
7.7
85
419
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
6.0
7.7
20
34
TPH07
NOMESCO Finland
Cathetrisation of artery
1.8
7.7
123
702
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
2.6
7.6
54
216
TJD10
NOMESCO Finland
Insertion of other tube into stomach or duodenum
18.5
7.6
11
6
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.9
7.6
111
613
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.7
7.5
177
1135
F10.20
ICD-10 Finland
Alcohol dependence currently independent
4.5
7.5
25
57
N06AB04
ATC
citalopram; systemic
1.6
7.5
203
1353
ZXC10
NOMESCO Finland
Use of laser
3.4
7.5
34
102
AA1AD
NOMESCO Finland
CT of head and brain
1.5
7.4
267
1898
8070/3-C15.4
ICD-O-3
Squamous cell carcinoma, NOS, of middle third of esophagus
80.5
7.4
8
*
GBA35
NOMESCO Finland
Endoscopic insertion of stent into trachea
80.5
7.4
8
*
JBW97
NOMESCO Finland
Other laparoscopic operation on diaphragm or laparoscopic or thoracoscopic operation for gastro-oesophageal reflux
80.5
7.4
8
*
K31.7
ICD-10 Finland
Polyp of stomach and duodenum
80.5
7.4
8
*
K13.79
ICD-10 Finland
Change in the oral mucosa UNS
3.5
7.4
32
92
Z2446
NOMESCO Finland
Social worker
2.2
7.4
69
318
F10.00
ICD-10 Finland
Alcohol-related acute intoxication uncomplicated
4.8
7.3
23
49
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
7.3
474
3796
JCA42
NOMESCO Finland
Other endoscopic procedure for hemostasis
+∞
7.3
7
*
JCE96
NOMESCO Finland
Other reconstruction of oesophagus
+∞
7.3
7
*
K31.5
ICD-10 Finland
Obstruction of duodenum
+∞
7.3
7
*
JDB01
NOMESCO Finland
Laparoscopic gastrostomy
+∞
7.3
7
*
K29.2
ICD-10 Finland
Alcoholic gastritis
+∞
7.3
7
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.0
7.3
89
461
Z50.1
ICD-10 Finland
Other physical therapy
2.3
7.3
63
280
N06AB10
ATC
escitalopram; oral
1.7
7.2
157
986
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.1
7.2
79
389
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
7.1
382
2947
R50.9
ICD-10 Finland
Fever, unspecified
1.7
7.1
145
889
Z53.0
ICD-10 Finland
Procedure not carried out because of contraindication
20.1
7.1
10
5
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
5.3
7.1
20
38
93500
ICD-8 Finland
Foreign body in mouth, oesophagus and stomach
12.1
7.1
12
10
D13.2
ICD-10 Finland
Benign neoplasm: Duodenum
12.1
7.1
12
10
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
2.1
7.1
79
394
A04AA02
ATC
granisetron; systemic, transdermal
2.2
7.0
69
325
WF004
NOMESCO Finland
Palliative radiotherapy
3.2
7.0
35
113
N02BE01
ATC
paracetamol; systemic, rectal
1.5
7.0
931
8452
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
3.0
7.0
38
130
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
2.6
7.0
49
195
P15
ICPC
Chronic alcohol abuse
3.4
6.9
31
92
E87.6
ICD-10 Finland
Hypokalaemia
2.8
6.9
41
148
W19
ICD-10 Finland
Unspecified fall
1.9
6.9
102
566
XF600
NOMESCO Finland
Bloodpressure measurement
2.1
6.9
73
356
A11CC02
ATC
dihydrotachysterol; oral
13.9
6.9
11
8
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.6
6.9
172
1119
GD5AD
NOMESCO Finland
Thorax and upper abdomen combined CT examination of
4.8
6.9
21
44
N06AB03
ATC
fluoxetine; oral
1.8
6.8
116
675
C07AB07
ATC
bisoprolol; oral
1.4
6.8
545
4510
9351A
ICD-9 Finland
Foreign body in mouth, oesophagus and stomach, Oesophagus
11.0
6.8
12
11
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.0
6.8
87
458
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.4
6.8
55
238
N05AH03
ATC
olanzapine; systemic
2.4
6.8
55
238
1322
FHL
Esophagoscopy and foreign object removal
40.3
6.8
8
*
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.1
6.8
76
378
B37.01
ICD-10 Finland
Acute athrophy candidal stomatitis
22.6
6.7
9
*
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
3.0
6.6
35
118
GD1BA
NOMESCO Finland
Extensive X-ray examination of thorax
4.2
6.6
23
55
A02BA03
ATC
famotidine; systemic
2.5
6.6
47
189
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
2.5
6.6
47
189
Y69
ICD-10 Finland
Unspecified misadventure during surgical and medical care
5.9
6.6
17
29
R03BA05
ATC
fluticasone; inhalant
1.6
6.6
162
1050
TPX10
NOMESCO Finland
Implantation of vascular injection port
2.8
6.6
39
141
JN4AD
NOMESCO Finland
Body CT examination
1.9
6.6
90
487
SPAT1279
SPAT
Preparation of immediate hospitalisation
4.8
6.5
20
42
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.4
6.5
374
2913
R4130
NOMESCO Finland
Speech therapy
3.3
6.5
31
97
A04
ICPC
Weakness/tiredness general
1.7
6.5
131
801
D10
ICPC
Vomiting
2.8
6.5
39
143
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.1
6.5
70
345
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
6.4
220
1544
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.6
6.4
43
168
C16.04
ICD-10 Finland
Malignant tumor of cardiac intestinal carcinoma
70.2
6.4
7
*
C16.33
ICD-10 Finland
Malignant tumor of the antrum ventriculi diffuse carcinoma
70.2
6.4
7
*
C13.8
ICD-10 Finland
Malignant neoplasm: Overlapping lesion of hypopharynx
70.2
6.4
7
*
R63.8
ICD-10 Finland
Other symptoms and signs concerning food and fluid intake
70.2
6.4
7
*
SPAT1124
SPAT
Replacement of gastrostomy tube
70.2
6.4
7
*
WX704
NOMESCO Finland
Intubation
2.0
6.4
74
374
J37.0
ICD-10 Finland
Chronic laryngitis
3.1
6.4
32
104
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.7
6.4
39
145
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
3.2
6.3
30
94
S42.2
ICD-10 Finland
Fracture of upper end of humerus
2.4
6.3
51
219
ZZR10
NOMESCO Finland
Flap of skin and muscle
6.0
6.3
16
27
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.1
6.3
67
329
UGC02
NOMESCO Finland
Rigid bronchoscopy
9.3
6.3
12
13
JCA22
NOMESCO Finland
Endoscopic ligature of oesophageal varices
18.1
6.3
9
5
M01AB55
ATC
diclofenac, combinations; oral
2.0
6.3
77
400
1314
FHL
Esophagogastroscopy and other therapeutic procedure
+∞
6.3
6
*
J38.6
ICD-10 Finland
Stenosis of larynx
+∞
6.3
6
*
5300A
ICD-9 Finland
Diseases of oesophagus, Achalasia and cardiospasm
+∞
6.3
6
*
5322B
ICD-9 Finland
Duodenal ulcer, Acute with haemorrhage and perforation[ULCUS BULBI,VUOTAVA]
+∞
6.3
6
*
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
1.7
6.2
122
742
YA1BD
NOMESCO Finland
Extensive CT examination of head and neck for dose design of radiotherapy
5.1
6.2
18
36
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
2.2
6.2
58
267
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
1.9
6.2
90
496
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.5
6.2
202
1405
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.1
6.2
65
315
SPAT1255
SPAT
Intravenous administration of medicine
2.0
6.2
76
394
D07AC01
ATC
betamethasone; topical
1.4
6.2
338
2608
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.1
6.1
63
304
H25.8
ICD-10 Finland
Other senile cataract
1.7
6.1
131
818
A02BD03
ATC
lansoprazole, amoxicillin and metronidazole; systemic
2.0
6.1
72
368
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
7.7
6.1
13
17
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.6
6.1
176
1188
ZZA00
NOMESCO Finland
Split skin graft
2.7
6.1
40
154
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.6
6.1
158
1037
C16.0
ICD-10 Finland
Malignant neoplasm: Cardia
12.6
6.1
10
8
PJD71
NOMESCO Finland
Extended sparing excision of cervical lymph nodes
8.6
6.1
12
14
8070/3-C32.9
ICD-O-3
Squamous cell carcinoma, NOS, of larynx, NOS
8.6
6.1
12
14
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
2.3
6.0
52
231
K44.0
ICD-10 Finland
Diaphragmatic hernia with obstruction, without gangrene
10.1
6.0
11
11
H02AB09
ATC
hydrocortisone; systemic
3.5
6.0
26
76
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.8
6.0
103
599
Mortality – FinRegistry
↥Association
Association between endpoint K11_OESOBST and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_OESOBST | 2.105 [1.86, 2.38] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.039 |
During the follow-up period (1.1.1998 — 31.12.2019), 1435 out of 3155 females with K11_OESOBST died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_OESOBST | 2.364 [2.09, 2.68] | < 0.001 |
| Birth year | 0.991 [0.98, 1.0] | 0.041 |
During the follow-up period (1.1.1998 — 31.12.2019), 2067 out of 4493 males with K11_OESOBST died.
Mortality risk
Mortality risk for people of age
years, who have K11_OESOBST.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.172% | 0.425% |
| 5 | 1.071% | 2.722% |
| 10 | 2.621% | 7.782% |
| 15 | 5.238% | 14.343% |
| 20 | 9.321% | 23.381% |
Relationships between endpoints
↥Index endpoint: K11_OESOBST – Oesophageal obstruction
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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