Other diseases of peritoneum

K11_OTHPERITON

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K66
  • Hospital discharge: ICD-9 568
  • Hospital discharge: ICD-8 569
  • Hospital discharge: excluded ICD-8 56902
  • Cause of death: ICD-10 K66
  • Cause of death: ICD-9 568
  • Cause of death: ICD-8 569
  • Cause of death: excluded ICD-8 56902

2 out of 7 registries used, show all original rules.

1705

4. Check minimum number of events

None

1705

5. Include endpoints

None

1705

6. Filter based on genotype QC (FinnGen only)

1705

Control definitions (FinnGen only)

Control exclude
K11_PERITON

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
K65-K67
Name in latin
Aliae morbositates peritonei

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 15019 9767 5049
Only index persons 11222 7846 3376
Unadjusted period prevalence (%)
Whole population 0.23 0.28 0.14
Only index persons 0.24 0.29 0.13
Median age at first event (years)
Whole population 47.02 47.13 46.44
Only index persons 41.64 43.17 38.08

-FinnGen-

Key figures

All Female Male
Number of individuals 1705 1207 498
Unadjusted period prevalence (%) 0.36 0.41 0.22
Median age at first event (years) 42.87 42.13 44.66

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1563
Matched controls
15629
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K66.0
ICD-10 Finland
Peritoneal adhesions
+∞
323.0
650
*
56909
ICD-8 Finland
Other diseases of intestines and peritoneum, Unspecified
+∞
266.4
248
*
56908
ICD-8 Finland
Other diseases of intestines and peritoneum, Alii definiti
+∞
188.4
177
*
5680A
ICD-9 Finland
Other disorders of peritoneum, Peritoneal adhesions
+∞
154.8
146
*
JAP01
NOMESCO Finland
Laparoscopic freeing of adhesions in the peritoneal cavity
23.9
130.8
190
90
K66.1
ICD-10 Finland
Haemoperitoneum
+∞
126.8
120
*
JAH01
NOMESCO Finland
Laparoscopy
8.7
104.0
239
318
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.2
102.8
813
3908
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.9
63.8
492
2139
56907
ICD-8 Finland
Other diseases of intestines and peritoneum, Prolapsus recti
+∞
54.5
52
*
UJF32
NOMESCO Finland
Coloscopy
2.4
48.3
515
2620
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
15.1
44.7
75
52
JAH00
NOMESCO Finland
Laparotomy
7.5
42.2
103
146
56906
ICD-8 Finland
Other diseases of intestines and peritoneum, Prolapsus ani
+∞
41.8
40
*
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
9.6
41.3
86
94
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
4.2
40.2
164
426
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.1
39.8
248
905
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.6
39.0
339
1517
K66.8
ICD-10 Finland
Other specified disorders of peritoneum
+∞
38.7
37
*
N02AX02
ATC
tramadol; systemic, rectal
2.0
37.2
742
4845
6561
FHL
Removal of fasteners and related measures
31.5
37.1
49
16
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
5.9
36.0
104
186
N80.3
ICD-10 Finland
Endometriosis of pelvic peritoneum
6.4
34.2
92
150
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
32.4
518
3052
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
4.1
32.4
134
352
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.2
30.8
122
307
1410
FHL
Laparoscopy
4.7
28.8
102
230
6146A
ICD-9 Finland
Inflammatory disease of ovary, Fallopian tube, pelvic cellular tissue and peritoneum, Pelvic peritoneal adhesions, female
8.9
28.4
61
71
JN3AD
NOMESCO Finland
Abdominal CT examination
3.2
28.2
161
547
A02BC05
ATC
esomeprazole; systemic
1.8
27.6
676
4587
N80.1
ICD-10 Finland
Endometriosis of ovary
5.3
26.9
84
165
N03AX16
ATC
pregabalin; oral
2.0
26.5
422
2443
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
2.6
26.5
212
890
K66.9
ICD-10 Finland
Disorder of peritoneum, unspecified
+∞
26.1
25
*
A06AD11
ATC
lactulose; oral
2.3
25.8
272
1318
JAL97
NOMESCO Finland
Other laparoscopic excision of lesion of peritoneum
264.7
25.8
26
*
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
25.2
458
2778
N80.9
ICD-10 Finland
Endometriosis, unspecified
7.7
24.7
58
78
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.1
23.9
314
1674
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
22.7
664
4674
A06AC01
ATC
ispaghula (psylla seeds); oral
1.9
22.6
427
2606
JAW97
NOMESCO Finland
Other laparoscopic operation on abdominal wall, peritoneum, mesentery or omentum
121.8
22.6
24
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.0
22.3
344
1948
8351
FHL
Removal of pelvic floor brackets
12.9
22.2
39
31
JAL21
NOMESCO Finland
Laparoscopic excision or destruction of lesion of peritoneum
8.5
22.0
48
58
56901
ICD-8 Finland
Other diseases of intestines and peritoneum, Perforatio intestini NUD
+∞
21.9
21
*
P01AB01
ATC
metronidazole; oral, rectal
1.7
21.9
667
4734
45599
ICD-8 Finland
Haemorrhoids
4.4
21.7
81
193
A02BC01
ATC
omeprazole; systemic
1.8
21.7
464
2948
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.2
21.3
229
1111
R07.4
ICD-10 Finland
Chest pain, unspecified
1.8
20.9
440
2774
J01DA01
ATC
[U] cefalexin; systemic
1.7
20.7
988
7913
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
3.9
20.6
87
233
JFB00
NOMESCO Finland
Partial resection of small intestine
6.9
20.4
51
76
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
3.7
20.3
90
251
R51.80
ICD-10 Finland
Headache
2.1
20.3
250
1287
A02BA02
ATC
ranitidine; systemic
1.9
20.2
354
2095
SPAT1263
SPAT
Sampling
1.7
20.0
655
4708
56905
ICD-8 Finland
Other diseases of intestines and peritoneum, Fistula faecalis
+∞
19.8
19
*
K65.0
ICD-10 Finland
Acute peritonitis
202.4
19.6
20
*
A02BC03
ATC
lansoprazole; oral
1.7
19.1
491
3278
A03CA02
ATC
clidinium and psycholeptics; oral
2.7
18.8
131
505
R10.0
ICD-10 Finland
Acute abdomen
4.1
18.5
74
189
6202X
ICD-9 Finland
Noninflammatory disorders of ovary, Fallopian tube and broad ligament, Other and unspecified ovarian cyst
5.7
18.5
53
95
J01MA02
ATC
ciprofloxacin; systemic
1.7
18.5
604
4314
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.5
18.4
157
680
JFK10
NOMESCO Finland
Freeing of adhesions in intestinal obstruction
22.0
18.2
26
12
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.2
18.1
194
939
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.4
17.9
161
715
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.1
17.7
222
1150
N73.6
ICD-10 Finland
Female pelvic peritoneal adhesions
7.9
17.6
40
52
61610
ICD-8 Finland
Diseases of parametrium and pelvic peritoneum (female), Pelvic peritoneal adhesions, female
6.8
17.1
43
65
N06AA09
ATC
amitriptyline; systemic
2.1
17.1
199
998
8113
FHL
Fractional scraping
2.6
17.1
133
546
N05CF01
ATC
zopiclone; oral
1.7
17.0
517
3597
N99.4
ICD-10 Finland
Postprocedural pelvic peritoneal adhesions
7.4
17.0
40
55
N02BE01
ATC
paracetamol; systemic, rectal
1.8
16.9
1319
11728
UKC02
NOMESCO Finland
Cystoscopy
2.0
16.8
247
1362
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.4
16.7
143
619
N70.1
ICD-10 Finland
Chronic salpingitis and oophoritis
6.1
16.5
45
76
N03AX12
ATC
gabapentin; oral
1.9
16.5
254
1425
UJD02
NOMESCO Finland
Gastroscopy
2.9
16.4
101
361
J01MA12
ATC
levofloxacin; systemic
1.9
16.2
289
1706
H02AB06
ATC
prednisolone; systemic
1.6
16.1
709
5403
5608A
ICD-9 Finland
Intestinal obstruction without mention of hernia, Other specified intestinal obstruction[OBSTRUCTIO INTESTINALIS ,ADHESIONES INTRAABDOMINALE]
16.9
16.1
25
15
K59.0
ICD-10 Finland
Constipation
2.8
16.0
105
389
M79.6
ICD-10 Finland
Pain in limb
1.6
15.9
552
3963
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
6.4
15.8
41
65
B01AB05
ATC
enoxaparin; parenteral
1.6
15.8
470
3238
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.2
15.7
173
846
D01
ICPC
Abdominal pain/cramps general
2.2
15.6
169
820
JFK01
NOMESCO Finland
Laparoscopic division of adhesive band in intestinal obstruction
38.4
15.4
19
5
A03FA02
ATC
cisapride; oral, rectal
2.3
15.3
153
716
G03DC03
ATC
lynestrenol; oral
4.4
15.3
55
128
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.6
15.2
452
3110
N06AX16
ATC
venlafaxine; oral
2.0
15.2
224
1234
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
15.1
676
5147
JFW97
NOMESCO Finland
Other laparoscopic operation on intestine
45.4
15.1
18
*
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
2.2
15.0
164
797
N05BA04
ATC
oxazepam; oral
1.7
14.9
397
2649
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
2.0
14.8
212
1153
N80.81
ICD-10 Finland
Endometriosis in sacrouteral ligament
80.8
14.6
16
*
C07AB07
ATC
bisoprolol; oral
1.5
14.6
687
5283
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.2
14.5
147
690
G44.2
ICD-10 Finland
Tension-type headache
1.9
14.5
217
1202
WX302
NOMESCO Finland
Thoracal epidural anesthesy
2.8
14.4
94
349
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.6
14.4
435
2993
Z01.8
ICD-10 Finland
Other specified special examinations
1.7
14.4
328
2087
J02AC01
ATC
fluconazole; systemic
1.5
14.3
644
4889
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.1
14.3
170
857
N83.1
ICD-10 Finland
Corpus luteum cyst
5.6
14.2
41
75
UJF30
NOMESCO Finland
Ileoscopy through colon
2.1
13.9
159
792
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
13.6
276
1691
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
13.6
271
1651
N80.0
ICD-10 Finland
Endometriosis of uterus
3.7
13.6
58
159
M17.1
ICD-10 Finland
Other primary gonarthrosis
1.7
13.6
336
2187
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
13.3
593
4473
SPAT1153
SPAT
Removal of sutures
1.6
13.3
475
3402
ZXD05
NOMESCO Finland
Urgent procedure
1.6
13.2
458
3252
R53
ICD-10 Finland
Malaise and fatigue
1.7
13.1
313
2012
K56.0
ICD-10 Finland
Paralytic ileus
8.4
13.0
28
34
8201
FHL
Ovarian preservation exploration and related procedures, eg resection, enucleation or ovariolysis
4.7
12.8
43
94
M01AE02
ATC
naproxen; oral, rectal
1.5
12.8
838
6846
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.6
12.5
443
3154
H02AB07
ATC
prednisone; oral
1.8
12.5
229
1356
56900
ICD-8 Finland
Other diseases of intestines and peritoneum, Abscessus intestini
+∞
12.5
12
*
N06AX11
ATC
mirtazapine; oral
1.5
12.3
464
3349
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
4.5
12.3
43
98
J01FA10
ATC
azithromycin; systemic
1.5
12.2
827
6776
M54.5
ICD-10 Finland
Low back pain
1.5
12.2
479
3490
D06
ICPC
Abdominal pain localized other
2.2
12.0
128
616
A02BC02
ATC
pantoprazole; systemic
1.5
12.0
969
8215
N80.4
ICD-10 Finland
Endometriosis of rectovaginal septum and vagina
6.3
12.0
31
50
G04BD04
ATC
oxybutynin; oral, transdermal
2.4
12.0
100
429
78551
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Symptomata abdominalis acuta NUD
3.1
12.0
66
221
M01AX17
ATC
nimesulide; oral
1.6
12.0
383
2658
R11
ICD-10 Finland
Nausea and vomiting
2.1
11.8
129
628
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.7
11.8
79
300
LAF00
NOMESCO Finland
Unilateral salpingo-oophorectomy
4.8
11.8
38
80
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.8
11.7
212
1248
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.9
11.7
169
921
SPAT1262
SPAT
Handing over of treatment supplies
1.7
11.7
263
1656
J45.9
ICD-10 Finland
Asthma, unspecified
1.7
11.7
269
1706
R03BA05
ATC
fluticasone; inhalant
1.7
11.6
259
1631
8204
FHL
Salpingo-oophorectomy
4.7
11.5
38
82
XF402
NOMESCO Finland
ECG with work load test
1.9
11.5
173
953
121
Kela drug reimbursment
Severe hypofunction of sexual glands
3.7
11.5
50
140
M03BX02
ATC
tizanidine; oral
1.5
11.5
910
7654
5688X
ICD-9 Finland
Other disorders of peritoneum, Other specified disorders of peritoneum
+∞
11.5
11
*
56903
ICD-8 Finland
Other diseases of intestines and peritoneum, Periproctitis
+∞
11.5
11
*
M01AE03
ATC
ketoprofen; systemic, rectal
1.5
11.4
575
4411
N06AX21
ATC
duloxetine; oral
1.9
11.3
171
947
AA1AD
NOMESCO Finland
CT of head and brain
1.6
11.2
332
2254
1413
FHL
Laparoscopy and other therapeutic procedure
2.9
11.2
69
246
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
11.2
532
4029
JKA20
NOMESCO Finland
Cholecystectomy
3.2
11.0
57
183
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.9
11.0
171
955
6171A
ICD-9 Finland
Endometriosis of ovary
4.4
11.0
39
91
N02AA05
ATC
oxycodone; systemic
1.7
11.0
222
1352
R42
ICD-10 Finland
Dizziness and giddiness
1.6
11.0
329
2238
Y0599
ICD-8 Finland
Investigation of digestive system
4.0
10.9
42
106
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.8
10.9
188
1091
TPH07
NOMESCO Finland
Cathetrisation of artery
1.9
10.9
155
841
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.4
10.7
92
401
M79.1
ICD-10 Finland
Myalgia
1.8
10.7
188
1097
K59.09
ICD-10 Finland
Constipation, unspecified
2.3
10.7
101
460
ZXE20
NOMESCO Finland
More than three and less than five hours
1.8
10.7
201
1199
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
10.6
314
2128
K45.8
ICD-10 Finland
Other specified abdominal hernia without obstruction or gangrene
11.3
10.6
19
17
LBE01
NOMESCO Finland
Laparoscopic salpingectomy
3.4
10.5
49
146
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
10.5
317
2162
LCD00
NOMESCO Finland
Hysterectomy
2.3
10.5
97
437
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.2
10.5
107
505
JFK97
NOMESCO Finland
Other laparoscopic operation on adhesions in intestinal obstruction
110.7
10.4
11
*
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
3.5
10.4
48
142
S18
ICPC
Laceration/cut
1.4
10.4
580
4524
N05BA01
ATC
diazepam; systemic, rectal
1.7
10.4
210
1281
N06AB04
ATC
citalopram; systemic
1.6
10.4
331
2287
M25.5
ICD-10 Finland
Pain in joint
1.5
10.3
412
2994
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.5
10.3
372
2645
J01FF01
ATC
clindamycin; systemic
1.5
10.3
385
2759
N80.8
ICD-10 Finland
Other endometriosis
10.7
10.3
19
18
K50.9
ICD-10 Finland
Crohn disease, unspecified
4.8
10.3
33
70
8307
FHL
Hysterectomy and unilateral removal of adhesions
5.1
10.2
31
62
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.7
10.2
235
1490
56096
ICD-8 Finland
Intestinal obstruction without mention of hernia, Ileus propter adhaesionem (functione laesa circulationis intestinalis non indicata)
13.2
10.2
17
13
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
10.2
510
3888
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.9
10.1
149
817
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
2.7
10.1
69
266
A03CA05
ATC
glycopyrronium bromide and psycholeptics; systemic
4.7
10.0
33
72
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
3.2
10.0
51
163
J01DB01
ATC
cefalexin; oral
1.5
10.0
1195
10734
R06.0
ICD-10 Finland
Dyspnoea
1.5
10.0
348
2451
R03AC02
ATC
salbutamol; inhalant
1.4
9.9
755
6222
R01AD08
ATC
fluticasone; nasal
1.5
9.9
410
2999
K56.7
ICD-10 Finland
Ileus, unspecified
4.3
9.9
35
82
6421
FHL
Appendicectomy
2.3
9.9
88
388
Y60
ICD-10 Finland
Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
5.3
9.8
29
56
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
1.8
9.8
172
1004
C03CA01
ATC
furosemide; systemic
1.5
9.8
401
2927
K50.0
ICD-10 Finland
Crohn disease of small intestine
4.5
9.8
33
74
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
9.7
220
1387
355
Kela drug reimbursment
Dienogest
55.3
9.7
11
*
JEA00
NOMESCO Finland
Appendectomy
2.2
9.6
94
434
WX110
NOMESCO Finland
Local anesthesy
1.4
9.6
963
8322
M01AH05
ATC
etoricoxib; oral
1.4
9.6
840
7084
N80.5
ICD-10 Finland
Endometriosis of intestine
15.1
9.5
15
10
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
9.5
712
5837
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.5
9.5
74
306
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
9.5
581
4592
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.0
9.4
128
681
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.7
9.4
208
1302
SPAT1148
SPAT
Treatment of chronic ulcer or burn
1.7
9.4
187
1134
JAL96
NOMESCO Finland
Other excision of lesion of peritoneum
+∞
9.4
9
*
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.0
9.3
121
631
M01AB05
ATC
diclofenac; systemic, rectal
1.4
9.3
974
8454
A02BC04
ATC
rabeprazole; oral
1.9
9.3
135
738
J01AA02
ATC
doxycycline; systemic
1.4
9.3
1178
10600
8306
FHL
Hysterectomy (related to abortion 8516, prolapse correction 8436)
2.6
9.3
67
268
6266A
ICD-9 Finland
Disorders of menstruation and other abnormal bleeding from female genital tract, Metrorrhagia
2.7
9.2
62
237
6101
FHL
Exploratory laparotomy, includes possible biopases
13.7
9.2
15
11
N06AB03
ATC
fluoxetine; oral
1.7
9.2
191
1175
A03DA02
ATC
pitofenone and analgesics; systemic
3.2
9.1
47
152
K57.2
ICD-10 Finland
Diverticular disease of large intestine with perforation and abscess
3.5
9.1
41
120
JFB46
NOMESCO Finland
Resection of sigmoid colon
4.7
9.0
29
62
I10
ICD-10 Finland
Essential (primary) hypertension
1.4
9.0
810
6826
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.6
9.0
286
1965
M01AG02
ATC
tolfenamic acid; oral, rectal
1.6
9.0
237
1558
N94.5
ICD-10 Finland
Secondary dysmenorrhoea
3.6
8.9
38
106
J01FA06
ATC
roxithromycin; oral
1.4
8.8
598
4795
WX320
NOMESCO Finland
Spinalanesthesy
1.5
8.8
312
2203
WX002
NOMESCO Finland
Sedation and analgesia
1.5
8.6
278
1917
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
3.8
8.6
35
94
A03FA01
ATC
metoclopramide; systemic, rectal
1.5
8.6
317
2250
JAD11
NOMESCO Finland
Laparoscopic repair of incisional hernia
4.7
8.6
28
61
JAD10
NOMESCO Finland
Repair of incisional hernia
5.8
8.6
23
40
A07EC02
ATC
mesalazine; oral, rectal
2.2
8.5
80
366
XF400
NOMESCO Finland
ECG with 12 standard connections
1.6
8.5
225
1477
G47.3
ICD-10 Finland
Sleep apnoea
1.6
8.5
264
1804
TLC00
NOMESCO Finland
Insertion of intrauterine device
2.1
8.5
91
439
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
3.5
8.5
38
111
56899
ICD-8 Finland
Peritoneal adhesions
27.7
8.5
11
*
R05FA02
ATC
opium derivatives and expectorants; systemic
1.4
8.5
582
4671
M70.6
ICD-10 Finland
Trochanteric bursitis
1.7
8.4
189
1185
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.7
8.4
161
964
H02AB04
ATC
methylprednisolone; systemic
1.6
8.4
216
1406
K65.9
ICD-10 Finland
Peritonitis, unspecified
+∞
8.3
8
*
J01EA01
ATC
trimethoprim; systemic
1.4
8.3
399
2995
WX704
NOMESCO Finland
Intubation
2.0
8.2
104
539
R07.3
ICD-10 Finland
Other chest pain
1.8
8.2
137
789
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.7
8.1
160
971
N80.89
ICD-10 Finland
Endometriosis with other specified or multiple localization
9.0
8.0
16
18
62660
ICD-8 Finland
Disorders of menstruation, Intermenstrual bleeding
2.8
8.0
51
189
T81.9
ICD-10 Finland
Unspecified complication of procedure
3.6
8.0
34
96
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
3.1
7.9
41
134
N97.1
ICD-10 Finland
Female infertility of tubal origin
4.8
7.9
25
53
SPAT1283
SPAT
Restricted health certificate
1.6
7.9
198
1280
A02BA03
ATC
famotidine; systemic
2.3
7.9
68
299
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.7
7.9
181
1143
R52.2
ICD-10 Finland
Other chronic pain
2.6
7.9
55
216
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
1.7
7.9
160
975
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.6
7.9
56
223
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
2.5
7.9
61
253
L13
ICPC
Hip symptom/complaint
1.6
7.9
227
1522
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
1.9
7.8
112
611
A02BX02
ATC
sucralfate; oral
2.3
7.8
72
326
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.7
7.8
167
1032
LAF01
NOMESCO Finland
Laparoscopic unilateral salpingo-oophorectomy
2.9
7.8
46
164
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.5
7.8
268
1875
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
2.4
7.7
64
277
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.4
7.7
64
277
C10AC01
ATC
colestyramine; oral
2.8
7.7
49
181
A07AA02
ATC
nystatin; oral
2.0
7.7
95
491
SPAT1312
SPAT
General health counselling
1.4
7.7
429
3305
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
2.3
7.7
68
301
N03AE01
ATC
clonazepam; systemic
2.0
7.7
92
468
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.4
7.7
61
259
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.4
7.7
534
4277
R51
ICD-10 Finland
Headache
2.2
7.6
71
326
JFB60
NOMESCO Finland
Resection of sigmoid colon with end colostomy
11.9
7.6
13
11
K43.0
ICD-10 Finland
Incisional hernia with obstruction, without gangrene
4.5
7.6
25
56
R02
ICPC
Shortness of breath/dyspnoea
1.7
7.5
163
1013
N70.0
ICD-10 Finland
Acute salpingitis and oophoritis
5.4
7.5
21
39
LAA10
NOMESCO Finland
Percutaneous or transvaginal puncture and recovery of oocyte
3.4
7.5
34
101
N05BA12
ATC
alprazolam; oral
1.7
7.5
153
935
M02AA07
ATC
piroxicam; topical
1.4
7.5
533
4279
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
1.9
7.5
107
582
G03DA04
ATC
progesterone; systemic, rectal, vaginal
2.3
7.5
67
300
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.1
7.5
77
368
M01AH01
ATC
celecoxib; oral (coxibs)
1.5
7.4
271
1916
J01FA09
ATC
clarithromycin; systemic
1.4
7.4
447
3487
SPAT1260
SPAT
Consultation of another employee
1.5
7.4
249
1730
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.3
7.4
67
302
JFK96
NOMESCO Finland
Other operation on adhesions in intestinal obstruction
80.4
7.4
8
*
G03DB08
ATC
dienogest; oral
80.4
7.4
8
*
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.1
7.4
81
396
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
1.9
7.4
102
546
JF2AD
NOMESCO Finland
Colon CT
13.4
7.4
12
9
H01CA02
ATC
nafarelin; nasal
2.8
7.4
45
165
SPAT1301
SPAT
No procedures
1.4
7.4
433
3362
SPAT1255
SPAT
Intravenous administration of medicine
2.0
7.4
92
477
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.9
7.3
108
596
L03
ICPC
Low back symptom/complaint
1.5
7.3
326
2402
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.6
7.3
199
1317
N80
ICD-10 Finland
Endometriosis
9.4
7.3
14
15
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.5
7.2
233
1604
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.0
7.2
91
473
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
15.8
7.2
11
7
6402
FHL
Small bowel resection
15.8
7.2
11
7
6173A
ICD-9 Finland
Endometriosis of pelvic peritoneum[ENDOMETRIOSIS SEROSAE PELVIS]
4.3
7.2
25
59
M03BC51
ATC
orphenadrine, combinations; systemic
1.4
7.2
397
3046
N05CD07
ATC
temazepam; oral
1.6
7.2
186
1213
6173B
ICD-9 Finland
Endometriosis of pelvic peritoneum[ENDOMETRIOSIS RETROUTERINA]
3.7
7.2
29
79
L04AX01
ATC
azathioprine; systemic
2.3
7.1
62
273
WX725
NOMESCO Finland
Noninvasive ventilation
2.2
7.1
68
315
F43.1
ICD-10 Finland
Post-traumatic stress disorder
3.2
7.1
35
111
R52.9
ICD-10 Finland
Pain, unspecified
1.8
7.1
124
721
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.1
7.1
73
350
UJF92
NOMESCO Finland
Capsular endoscopy
3.5
7.1
31
90
D91
ICPC
Abdominal hernia other
4.6
7.1
23
51
O00.1
ICD-10 Finland
Tubal pregnancy
3.7
7.1
29
80
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
1.8
7.1
120
694
M03BC01
ATC
orphenadrine (citrate); systemic
1.4
7.1
320
2364
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.2
7.0
65
298
LAC21
NOMESCO Finland
Laparoscopic destruction of lesion of ovary
4.7
7.0
22
47
E66.01
ICD-10 Finland
Obesity due to excess calories
1.9
7.0
103
566
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.6
7.0
185
1212
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
2.1
7.0
76
373
N97.8
ICD-10 Finland
Female infertility of other origin
3.8
7.0
27
71
Z31.2
ICD-10 Finland
In vitrofertilization
6.3
6.9
17
27
LBE00
NOMESCO Finland
Salpingectomy
6.3
6.9
17
27
E66.8
ICD-10 Finland
Other obesity
2.0
6.9
80
401
RF210
NOMESCO Finland
NA
2.8
6.9
42
154
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.4
6.9
377
2884
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
7.6
6.9
15
20
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
3.3
6.9
32
98
J46
ICD-10 Finland
Status asthmaticus
2.9
6.9
40
142
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.5
6.8
51
207
NAG41
NOMESCO Finland
Anterior fusion of cervical spine with fixation
8.3
6.8
14
17
6201A
ICD-9 Finland
Noninflammatory disorders of ovary, Fallopian tube and broad ligament, Corpus luteum cyst or haematoma
6.7
6.8
16
24
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.7
6.8
130
781
K92.9
ICD-10 Finland
Disease of digestive system, unspecified
9.3
6.8
13
14
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.8
6.8
105
590
R05FB02
ATC
cough suppressants and expectorants
1.3
6.8
548
4476
PD1BD
NOMESCO Finland
Extensive CT of abdominal aorta and branches
4.7
6.7
21
45
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.5
6.7
232
1623
N92.0
ICD-10 Finland
Excessive and frequent menstruation with regular cycle
1.7
6.7
135
823
JAB11
NOMESCO Finland
Laparoscopic repair of inguinal hernia
3.5
6.6
29
85
G03GA06
ATC
follitropin beta; parenteral
2.9
6.6
38
133
TKC20
NOMESCO Finland
Catheterisation of bladder
1.9
6.6
96
527
QBJ30
NOMESCO Finland
Correction of abdominal apron
4.6
6.6
21
46
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
1.8
6.6
107
610
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
1.6
6.6
193
1300
JFA70
NOMESCO Finland
Suture of small intestine
12.3
6.6
11
9
JFG20
NOMESCO Finland
Closure of enterostomy with resection of exteriorised loop
12.3
6.6
11
9
2200A
ICD-9 Finland
Benign neoplasm of ovary[NEOPLASMA BENIGNUM OVARII]
3.9
6.6
25
65
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.4
6.6
366
2806
SPAT1254
SPAT
Administration of medicine
1.6
6.5
191
1284
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.0
6.5
84
442
62620
ICD-8 Finland
Disorders of menstruation, Excessive
3.2
6.5
31
97
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.5
6.5
274
1994
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
6.5
531
4339
JF1BD
NOMESCO Finland
Very extensive small bowel CT
5.7
6.5
17
30
JDF11
NOMESCO Finland
Laparoscopic gastric bypass
3.4
6.4
29
87
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
3.1
6.4
33
109
N05AA02
ATC
levomepromazine; systemic
2.2
6.4
61
284
Z54.0
ICD-10 Finland
Convalescence following surgery
3.5
6.4
28
82
N06AX05
ATC
trazodone; oral
2.7
6.4
42
161
JAA00
NOMESCO Finland
Incision of abdominal wall
14.4
6.4
10
7
R01BA52
ATC
pseudoephedrine, combinations; oral
1.4
6.4
452
3607
JBC01
NOMESCO Finland
Laparoscopic gastro-oesophageal antireflux operation
2.9
6.4
37
131
T81.2
ICD-10 Finland
Accidental puncture and laceration during a procedure, not elsewhere classified
3.7
6.4
26
72
LBF01
NOMESCO Finland
Laparoscopic perfusion of Fallopian tube
3.9
6.4
24
62
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
2.8
6.4
38
138
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
2.8
6.4
38
138
S80.1
ICD-10 Finland
Contusion of other and unspecified parts of lower leg
2.6
6.4
42
162
Z01.2
ICD-10 Finland
Dental examination
1.3
6.3
540
4433
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.5
6.3
221
1547
M01AH02
ATC
rofecoxib; oral
1.5
6.3
187
1263
K63.1
ICD-10 Finland
Perforation of intestine (nontraumatic)
5.5
6.3
17
31
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
1.9
6.3
92
508
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
1.9
6.3
92
508
KBV12
NOMESCO Finland
Transluminal endoscopic removal of stent from ureter
3.7
6.3
25
68
N83.0
ICD-10 Finland
Follicular cyst of ovary
3.3
6.3
29
89
X59
ICD-10 Finland
Exposure to unspecified factor
1.5
6.3
230
1627
5691A
ICD-9 Finland
Other disorders of intestine, Rectal prolapse
18.1
6.3
9
5
56300
ICD-8 Finland
Chronic enteritis and ulcerative colitis, Regional enteritis
18.1
6.3
9
5
X58
ICD-10 Finland
Exposure to other specified factors
1.6
6.3
163
1067
JAK03
NOMESCO Finland
Laparotomy and peritoneal irrigation
26.8
6.2
8
*
R21
ICPC
Throat symptom/complaint
1.5
6.2
240
1717
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
2.5
6.2
47
194
2180A
ICD-9 Finland
Uterine leiomyoma, Submucous leiomyoma of uterus
1.9
6.2
89
489
K50.8
ICD-10 Finland
Other Crohn disease
3.5
6.1
26
75
SPAT1211
SPAT
Application of soft bandage
1.7
6.1
122
744
8117
FHL
Pertubatio
12.6
6.1
10
8
NBG10
NOMESCO Finland
Acromioplastia
2.5
6.0
43
172
ZXK00
NOMESCO Finland
Conversion from percutaneous endoscopic to open procedure
4.4
6.0
20
46
LCD01
NOMESCO Finland
Total laparoscopic hysterectomy
2.6
6.0
41
162
JAW96
NOMESCO Finland
Other operation on abdominal wall, peritoneum, mesentery or omentum
10.1
6.0
11
11
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.3
6.0
52
230
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
2.4
6.0
46
191
K57.9
ICD-10 Finland
Diverticular disease of intestine, part unspecified, without perforation or abscess
2.8
6.0
35
125

Mortality – FinRegistry

Association

Association between endpoint K11_OTHPERITON and mortality.

Females

Parameter HR [95% CI] p-value
K11_OTHPERITON 1.474 [1.29, 1.68] < 0.001
Birth year 0.994 [0.99, 1.0] 0.169

During the follow-up period (1.1.1998 — 31.12.2019), 542 out of 3633 females with K11_OTHPERITON died.

Males

Parameter HR [95% CI] p-value
K11_OTHPERITON 1.577 [1.33, 1.87] < 0.001
Birth year 0.988 [0.98, 1.0] 0.026

During the follow-up period (1.1.1998 — 31.12.2019), 305 out of 1141 males with K11_OTHPERITON died.

Mortality risk

Mortality risk for people of age

years, who have K11_OTHPERITON.

N-year risk Females Males
1 0.072% 0.306%
5 0.756% 1.774%
10 1.976% 4.635%
15 3.855% 8.783%
20 6.688% 14.661%

Relationships between endpoints

Index endpoint: K11_OTHPERITON – Other diseases of peritoneum

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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