intestinal volvulus: A twisting in the intestine (INTESTINES) that can cause INTESTINAL OBSTRUCTION.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
991 |
4. Check minimum number of eventsNone |
991 |
5. Include endpointsNone |
991 |
6. Filter based on genotype QC (FinnGen only) |
991 |
Control definitions (FinnGen only)
- Control exclude
- K11_INTESTOTH
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- K56
- Name in latin
- Volvulus
Similar endpoints
↥List of similar endpoints to
Volvulus
based on the number of shared cases.
Similar with more cases:
- Paralytic ileus and intestinal obstruction
- Other diseases of intestines
- Gastrointestinal diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 10166 | 5114 | 4937 |
| Only index persons | 7288 | 3806 | 3482 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.14 | 0.15 | 0.14 |
| Only index persons | 0.14 | 0.14 | 0.13 |
| Median age at first event (years) | |||
| Whole population | 67.42 | 67.45 | 67.29 |
| Only index persons | 64.90 | 64.27 | 65.59 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 991 | 523 | 468 |
| Unadjusted period prevalence (%) | 0.19 | 0.18 | 0.21 |
| Median age at first event (years) | 64.54 | 59.45 | 70.23 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 876
- Matched controls
- 8759
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
K56.2
ICD-10 Finland
Volvulus
+∞
323.0
755
*
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
1627.5
257.6
238
*
JAH00
NOMESCO Finland
Laparotomy
53.2
166.8
199
48
K56.5
ICD-10 Finland
Intestinal adhesions [bands] with obstruction
+∞
149.3
139
*
JN3BD
NOMESCO Finland
Extensive abdominal CT
11.9
136.1
272
318
UJF32
NOMESCO Finland
Coloscopy
7.2
120.6
351
748
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
5.6
117.2
471
1500
JFB00
NOMESCO Finland
Partial resection of small intestine
77.2
112.2
126
19
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
12.2
101.1
195
201
K56.7
ICD-10 Finland
Ileus, unspecified
+∞
101.0
95
*
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
16.4
97.8
163
120
JFB30
NOMESCO Finland
Right hemicolectomy
48.9
94.9
115
27
ZXD05
NOMESCO Finland
Urgent procedure
4.6
92.5
457
1684
JN3AD
NOMESCO Finland
Abdominal CT examination
10.2
86.8
183
220
K59.09
ICD-10 Finland
Constipation, unspecified
21.2
85.0
128
70
K56.0
ICD-10 Finland
Paralytic ileus
+∞
69.7
66
*
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
84.4
69.3
77
10
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
15.4
67.4
114
84
WX302
NOMESCO Finland
Thoracal epidural anesthesy
10.0
64.8
136
158
WX408
NOMESCO Finland
General anesthesy, balanced
3.5
55.1
328
1269
JAP00
NOMESCO Finland
Freeing of adhesions in the peritoneal cavity
72.6
53.9
61
9
JFB46
NOMESCO Finland
Resection of sigmoid colon
44.5
53.7
66
16
5602C
ICD-9 Finland
Intestinal obstruction without mention of hernia, Volvulus[VOLVULUS INTESTINI TENUIS]
+∞
53.7
51
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.2
46.8
310
1266
56020
ICD-8 Finland
Intestinal obstruction without mention of hernia, Volvulus
+∞
46.2
44
*
K59.0
ICD-10 Finland
Constipation
11.5
46.0
88
84
K59.00
ICD-10 Finland
Constipation caused by slow bowel passage (SCT)
101.4
44.2
48
5
R10.0
ICD-10 Finland
Acute abdomen
12.5
41.5
76
66
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
32.4
39.6
52
17
A06AC01
ATC
ispaghula (psylla seeds); oral
3.2
38.1
244
950
A06AD11
ATC
lactulose; oral
3.4
35.7
203
720
JAH01
NOMESCO Finland
Laparoscopy
7.7
35.3
85
121
JFK10
NOMESCO Finland
Freeing of adhesions in intestinal obstruction
+∞
33.5
32
*
K63.1
ICD-10 Finland
Perforation of intestine (nontraumatic)
+∞
31.4
30
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.0
30.7
209
834
ZXE10
NOMESCO Finland
More than one and less than three hours
2.3
28.2
368
2093
JFB20
NOMESCO Finland
Ileocaecal resection
55.2
27.3
32
6
6561
FHL
Removal of fasteners and related measures
77.7
26.9
30
*
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
6.0
26.3
75
135
JFL10
NOMESCO Finland
Laparotomy and manipulation of obstructed intestine
+∞
26.2
25
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.9
25.1
168
652
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.8
25.1
115
338
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.9
24.9
167
648
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
3.9
24.2
105
294
TPH07
NOMESCO Finland
Cathetrisation of artery
3.2
23.1
135
478
K59.1
ICD-10 Finland
Functional diarrhoea
6.7
22.7
59
94
JFK00
NOMESCO Finland
Division of adhesive band in intestinal obstruction
123.2
22.7
24
*
UJF30
NOMESCO Finland
Ileoscopy through colon
4.7
22.5
80
185
N02BE01
ATC
paracetamol; systemic, rectal
2.4
22.3
733
5987
C10AC01
ATC
colestyramine; oral
10.0
22.0
44
46
JFB47
NOMESCO Finland
Laparoscopic resection of sigmoid colon
25.8
21.9
30
12
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.6
21.9
79
186
A02BC02
ATC
pantoprazole; systemic
2.0
21.6
552
4012
TPH04
NOMESCO Finland
Cathetrisation of vein
2.4
21.4
211
1020
6402
FHL
Small bowel resection
+∞
20.9
20
*
K65.0
ICD-10 Finland
Acute peritonitis
17.4
20.6
32
19
P01AB01
ATC
metronidazole; oral, rectal
2.1
20.5
318
1885
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
8.1
20.0
45
58
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
6.9
19.9
50
76
D01
ICPC
Abdominal pain/cramps general
3.6
19.9
93
277
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
7.3
19.9
48
69
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
14.2
19.7
33
24
D12
ICPC
Constipation
6.5
19.5
51
82
N05AH04
ATC
quetiapine; oral
2.6
19.4
158
685
Z2446
NOMESCO Finland
Social worker
4.0
19.3
80
215
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.5
19.2
170
770
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.8
19.0
135
538
N06AB04
ATC
citalopram; systemic
2.3
18.4
207
1056
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.1
18.4
262
1483
R53
ICD-10 Finland
Malaise and fatigue
2.3
18.3
198
993
ZXE20
NOMESCO Finland
More than three and less than five hours
2.6
18.1
148
640
JFB60
NOMESCO Finland
Resection of sigmoid colon with end colostomy
33.7
18.0
23
7
B01AB05
ATC
enoxaparin; parenteral
2.0
17.9
280
1644
R11
ICD-10 Finland
Nausea and vomiting
3.5
17.9
88
273
K59.9
ICD-10 Finland
Functional intestinal disorder, unspecified
23.3
17.8
25
11
WX002
NOMESCO Finland
Sedation and analgesia
2.3
17.7
190
946
K92.1
ICD-10 Finland
Melaena
4.8
17.6
60
133
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.0
17.0
280
1673
Z3226
NOMESCO Finland
Physiotherapist
2.3
16.8
173
841
5602A
ICD-9 Finland
Intestinal obstruction without mention of hernia, Volvulus[VOLVULUS SIGMAE]
+∞
16.7
16
*
K55.0
ICD-10 Finland
Acute vascular disorders of intestine
+∞
16.7
16
*
45599
ICD-8 Finland
Haemorrhoids
+∞
16.7
16
*
K91.2
ICD-10 Finland
Postsurgical malabsorption, not elsewhere classified
+∞
16.7
16
*
UJF12
NOMESCO Finland
Enteroscopy through intestinal stoma
173.1
16.5
17
*
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
4.2
16.4
63
158
UJF14
NOMESCO Finland
Enteroscopy of ileoanal anastomosis
40.9
16.4
20
5
WX404
NOMESCO Finland
Intravenous generell anesthesy
2.2
16.4
185
939
N02AX02
ATC
tramadol; systemic, rectal
1.9
16.1
356
2358
J01MA02
ATC
ciprofloxacin; systemic
1.9
16.0
338
2199
JN4BD
NOMESCO Finland
Extensive body CT
2.6
16.0
121
500
5609X
ICD-9 Finland
Intestinal obstruction without mention of hernia, Unspecified intestinal obstruction
+∞
15.7
15
*
5602B
ICD-9 Finland
Intestinal obstruction without mention of hernia, Volvulus[VOLVULUS COLI ALIUS]
+∞
15.7
15
*
N06AX11
ATC
mirtazapine; oral
2.0
15.6
262
1566
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
15.5
376
2555
JAD30
NOMESCO Finland
Repair of incisional hernia using prosthetic material
9.2
15.5
32
36
JFG00
NOMESCO Finland
Closure of loop enterostomy without resection
162.7
15.5
16
*
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.5
15.5
135
602
N03AX16
ATC
pregabalin; oral
2.1
14.8
199
1085
Z3231
NOMESCO Finland
Registered nurse
1.9
14.8
248
1479
K56.1
ICD-10 Finland
Intussusception
+∞
14.6
14
*
K62.3
ICD-10 Finland
Rectal prolapse
+∞
14.6
14
*
JFH10
NOMESCO Finland
Total colectomy and ileostomy
81.5
14.6
16
*
JAP01
NOMESCO Finland
Laparoscopic freeing of adhesions in the peritoneal cavity
9.6
14.5
29
31
R50.9
ICD-10 Finland
Fever, unspecified
2.4
14.5
132
603
A03FA02
ATC
cisapride; oral, rectal
3.0
14.4
84
295
TJF80
NOMESCO Finland
Ostomy education
17.3
14.3
22
13
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.4
14.3
128
578
WX892
NOMESCO Finland
Monitored bed care
2.9
14.2
87
316
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
9.0
14.0
29
33
JFH00
NOMESCO Finland
Total colectomy and ileorectal anastomosis
30.6
13.9
18
6
R33
ICD-10 Finland
Retention of urine
2.8
13.9
90
339
S18
ICPC
Laceration/cut
1.8
13.8
342
2317
K57.2
ICD-10 Finland
Diverticular disease of large intestine with perforation and abscess
54.2
13.8
16
*
K57.9
ICD-10 Finland
Diverticular disease of intestine, part unspecified, without perforation or abscess
54.2
13.8
16
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.6
13.8
105
435
XF400
NOMESCO Finland
ECG with 12 standard connections
2.1
13.6
165
859
5608A
ICD-9 Finland
Intestinal obstruction without mention of hernia, Other specified intestinal obstruction[OBSTRUCTIO INTESTINALIS ,ADHESIONES INTRAABDOMINALE]
+∞
13.6
13
*
K59.3
ICD-10 Finland
Megacolon, not elsewhere classified
+∞
13.6
13
*
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.8
13.6
297
1932
JF1BD
NOMESCO Finland
Very extensive small bowel CT
34.6
13.5
17
5
B81
ICPC
Anaemia vit B12/folate deficiency
4.0
12.5
50
131
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
6.2
12.5
33
55
UJH02
NOMESCO Finland
Anoscopy
6.2
12.5
33
55
TKC20
NOMESCO Finland
Catheterisation of bladder
2.8
12.4
80
299
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.9
12.4
77
283
A28
ICPC
Limited function/disability NOS
2.1
12.4
156
822
B03BA03
ATC
hydroxocobalamin; parenteral
3.0
12.2
74
265
Z01.8
ICD-10 Finland
Other specified special examinations
2.0
12.2
168
918
WX882
NOMESCO Finland
High dependency care
4.6
12.1
41
92
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.3
12.1
118
555
T36
ICD-10 Finland
Poisoning by systemic antibiotics
4.2
12.0
45
111
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
4.5
12.0
42
97
A07EC02
ATC
mesalazine; oral, rectal
4.0
12.0
47
121
Z98.0
ICD-10 Finland
Intestinal bypass and anastomosis status
47.3
11.9
14
*
R4110
NOMESCO Finland
Physiotherapy
1.8
11.9
225
1382
J01MA12
ATC
levofloxacin; systemic
2.0
11.8
166
916
WX402
NOMESCO Finland
General anaesthesia
2.1
11.8
139
713
D64.9
ICD-10 Finland
Anaemia, unspecified
2.4
11.7
99
434
6421
FHL
Appendicectomy
3.3
11.4
56
175
N05CD07
ATC
temazepam; oral
2.1
11.3
131
665
ZXE00
NOMESCO Finland
One hour or less
1.7
11.3
317
2199
JWA00
NOMESCO Finland
Repair of wound dehiscence in gastroenterological surgery
17.3
11.2
17
10
JFF10
NOMESCO Finland
Loop enterostomy
25.4
11.2
15
6
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
4.8
11.1
36
77
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.7
11.0
47
131
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.3
10.8
54
171
AA1AD
NOMESCO Finland
CT of head and brain
1.8
10.8
212
1313
N05BA04
ATC
oxazepam; oral
1.8
10.8
204
1247
ZXK00
NOMESCO Finland
Conversion from percutaneous endoscopic to open procedure
9.7
10.8
21
22
N06AX16
ATC
venlafaxine; oral
2.2
10.8
108
516
N02AA05
ATC
oxycodone; systemic
2.0
10.7
137
727
T81.3
ICD-10 Finland
Disruption of operation wound, not elsewhere classified
5.2
10.7
32
63
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
5.4
10.7
31
59
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
4.6
10.6
36
81
N05CF01
ATC
zopiclone; oral
1.7
10.5
275
1862
RD210
NOMESCO Finland
NA
7.8
10.4
23
30
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.9
10.4
61
217
E0000UV
ATC
NA
1.7
10.2
301
2103
UJF92
NOMESCO Finland
Capsular endoscopy
9.3
10.0
20
22
K50.9
ICD-10 Finland
Crohn disease, unspecified
10.2
10.0
19
19
D18
ICPC
Change in faeces/bowel movements
6.2
10.0
26
43
UJG02
NOMESCO Finland
Proctoscopy
7.3
10.0
23
32
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
4.1
10.0
38
96
JF1CG
NOMESCO Finland
Extensive MRI of small bowel
40.5
10.0
12
*
6101
FHL
Exploratory laparotomy, includes possible biopases
16.9
9.9
15
9
N06AA09
ATC
amitriptyline; systemic
2.4
9.9
84
367
N03AX12
ATC
gabapentin; oral
2.1
9.9
121
629
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
3.5
9.8
44
129
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
9.7
139
768
T81.8
ICD-10 Finland
Other complications of procedures, not elsewhere classified
5.9
9.7
26
45
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.8
9.7
62
233
J01DB01
ATC
cefalexin; oral
1.6
9.6
638
5445
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.6
9.6
72
297
JDF11
NOMESCO Finland
Laparoscopic gastric bypass
8.5
9.6
20
24
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
3.7
9.5
40
111
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.6
9.5
68
273
K60.3
ICD-10 Finland
Anal fistula
101.1
9.4
10
*
JGC01
NOMESCO Finland
Laparoscopic rectopexy
101.1
9.4
10
*
JFC00
NOMESCO Finland
Entero-enterostomy
101.1
9.4
10
*
JF2BD
NOMESCO Finland
Extensive colon CT
12.5
9.4
16
13
JFF23
NOMESCO Finland
Transversostomy
8.2
9.4
20
25
Y83.9
ICD-10 Finland
Surgical procedure, unspecified as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.6
9.3
31
69
N04BD01
ATC
selegiline; oral
5.1
9.3
28
56
110
Kela drug reimbursment
Parkinson's disease and comparable movement disrorders
3.6
9.3
41
119
WX704
NOMESCO Finland
Intubation
2.6
9.2
69
284
C03CA01
ATC
furosemide; systemic
1.6
9.1
274
1909
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
3.0
9.1
52
180
K51.5
ICD-10 Finland
Left sided colitis
5.2
9.1
27
53
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.7
9.1
64
252
N05AH03
ATC
olanzapine; systemic
2.9
9.1
54
194
N05BA01
ATC
diazepam; systemic, rectal
2.1
9.1
111
574
N05BE01
ATC
buspirone; oral
4.6
9.0
30
67
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
2.8
9.0
56
205
J01FF01
ATC
clindamycin; systemic
1.7
9.0
201
1287
A06AC51
ATC
ispaghula, combinations; systemic
3.5
9.0
41
122
R06.0
ICD-10 Finland
Dyspnoea
1.7
9.0
192
1215
R15
ICD-10 Finland
Faecal incontinence
5.3
9.0
26
50
TPX10
NOMESCO Finland
Implantation of vascular injection port
4.1
8.9
33
82
JFF13
NOMESCO Finland
Terminal enterostomy
24.3
8.9
12
5
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.2
8.9
88
416
SPAT1254
SPAT
Administration of medicine
2.0
8.9
127
700
N06AX21
ATC
duloxetine; oral
2.4
8.9
75
327
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.0
8.9
118
635
G20
ICD-10 Finland
Parkinson disease
3.4
8.8
41
124
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
3.3
8.7
43
136
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.0
8.7
120
655
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.5
8.6
68
287
SPAT1229
SPAT
Assessment of need for aid
2.4
8.6
76
340
N05AA02
ATC
levomepromazine; systemic
3.2
8.6
44
144
K91.4
ICD-10 Finland
Colostomy and enterostomy malfunction
27.8
8.5
11
*
L28
ICPC
Limited function/disability (L)
1.9
8.5
140
815
K61.0
ICD-10 Finland
Anal abscess
90.9
8.4
9
*
JFA70
NOMESCO Finland
Suture of small intestine
90.9
8.4
9
*
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
3.7
8.4
35
97
X59
ICD-10 Finland
Exposure to unspecified factor
1.9
8.4
139
807
A41.9
ICD-10 Finland
Sepsis, unspecified
3.5
8.4
38
113
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
8.3
366
2790
F10.29
ICD-10 Finland
Addiction caused by alcohol UNS
5.6
8.3
23
42
L04AX01
ATC
azathioprine; systemic
3.3
8.3
40
125
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.8
8.3
143
842
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.1
8.3
99
509
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.3
8.2
77
357
UJF34
NOMESCO Finland
Left colonoscopy
14.6
8.2
13
9
N03AG01
ATC
valproic acid; systemic, rectal
2.7
8.2
53
202
A02BC01
ATC
omeprazole; systemic
1.7
8.2
216
1447
R4190
NOMESCO Finland
Nutritional therapy
4.2
8.1
29
70
S97
ICPC
Chronic ulcer skin
2.6
8.1
56
221
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
3.9
8.1
32
85
JF1AD
NOMESCO Finland
Small bowel CT
33.7
8.1
10
*
WX306
NOMESCO Finland
Lumbar epidural anesthesy
2.8
8.0
51
191
A02BC05
ATC
esomeprazole; systemic
1.6
8.0
293
2132
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
3.8
8.0
32
86
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.5
8.0
61
253
M79.6
ICD-10 Finland
Pain in limb
1.6
7.9
259
1835
L01BB02
ATC
mercaptopurine; oral
13.2
7.9
13
10
N06AB10
ATC
escitalopram; oral
1.8
7.8
138
820
J01EA01
ATC
trimethoprim; systemic
1.6
7.8
203
1354
D99
ICPC
Disease digestive system other
9.5
7.8
15
16
N31.2
ICD-10 Finland
Flaccid neuropathic bladder, not elsewhere classified
9.5
7.8
15
16
N06AB06
ATC
sertraline; oral
2.2
7.8
81
395
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.1
7.7
40
132
JFA73
NOMESCO Finland
Excision of lesion of small intestine
45.4
7.7
9
*
Z93.2
ICD-10 Finland
Ileostomy status
45.4
7.7
9
*
E86
ICD-10 Finland
Volume depletion
3.8
7.7
31
84
E87.6
ICD-10 Finland
Hypokalaemia
3.5
7.7
34
100
JFB50
NOMESCO Finland
Other resection of colon
25.2
7.6
10
*
T81.9
ICD-10 Finland
Unspecified complication of procedure
5.8
7.6
20
35
JBC01
NOMESCO Finland
Laparoscopic gastro-oesophageal antireflux operation
5.8
7.6
20
35
K50.1
ICD-10 Finland
Crohn disease of large intestine
10.1
7.5
14
14
UKC02
NOMESCO Finland
Cystoscopy
1.8
7.5
137
820
K30
ICD-10 Finland
Functional dyspepsia
2.2
7.5
72
338
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.2
7.4
76
366
A07AA09
ATC
vancomycin; oral
6.5
7.4
18
28
D50.8
ICD-10 Finland
Other iron deficiency anaemias
6.5
7.4
18
28
K63.8
ICD-10 Finland
Other specified diseases of intestine
80.7
7.4
8
*
U04
ICPC
Incontinence urine
3.0
7.4
42
145
UJD02
NOMESCO Finland
Gastroscopy
2.8
7.4
47
176
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
3.0
7.4
42
146
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.2
7.4
73
345
D10
ICPC
Vomiting
3.0
7.4
40
137
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.1
7.3
86
440
JFK01
NOMESCO Finland
Laparoscopic division of adhesive band in intestinal obstruction
+∞
7.3
7
*
5602D
ICD-9 Finland
Intestinal obstruction without mention of hernia, Volvulus[VOLVULUS OMENTI]
+∞
7.3
7
*
K62.4
ICD-10 Finland
Stenosis of anus and rectum
+∞
7.3
7
*
JF1DG
NOMESCO Finland
Small bowel very extensive MRI with with high intensity magnet
+∞
7.3
7
*
K56.4
ICD-10 Finland
Other impaction of intestine
+∞
7.3
7
*
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.9
7.3
43
155
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.1
7.3
84
427
N03AX09
ATC
lamotrigine; oral
3.6
7.2
31
89
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.6
7.2
203
1379
JFB43
NOMESCO Finland
Left hemicolectomy
15.9
7.2
11
7
W19
ICD-10 Finland
Unspecified fall
2.1
7.2
81
407
SPAT1125
SPAT
Stoma care and guidance
4.9
7.2
22
46
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.6
7.0
30
86
XKD06
NOMESCO Finland
Physiologic investigation of micturition
3.7
7.0
29
81
A07EA02
ATC
hydrocortisone; rectal
5.0
7.0
21
43
D06
ICPC
Abdominal pain localized other
2.4
7.0
55
234
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
4.1
6.9
25
62
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
3.2
6.9
34
109
N03AE01
ATC
clonazepam; systemic
2.6
6.9
48
190
K50.8
ICD-10 Finland
Other Crohn disease
7.6
6.9
15
20
A02BC03
ATC
lansoprazole; oral
1.6
6.9
216
1506
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
3.0
6.8
37
127
L02.9
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle, unspecified
4.2
6.8
24
58
D91
ICPC
Abdominal hernia other
8.3
6.8
14
17
D11
ICPC
Diarrhoea
2.1
6.8
72
353
WW500
NOMESCO Finland
Blood transfusion
3.1
6.8
35
116
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
3.8
6.8
27
73
R03AC12
ATC
salmeterol; inhalant
2.6
6.8
47
185
SPAT1262
SPAT
Handing over of treatment supplies
1.7
6.8
145
914
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
5.7
6.8
18
32
JWF00
NOMESCO Finland
Reoperation for insufficiency of anastomosis or suture in gastroenterological surgery
40.4
6.8
8
*
JFA58
NOMESCO Finland
Endoscopic dilatation of colon
40.4
6.8
8
*
JF2AB
NOMESCO Finland
Colongraphy with X-ray
40.4
6.8
8
*
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.4
6.8
56
243
WX610
NOMESCO Finland
Patient controlled analgesia
16.8
6.8
10
6
Z2221
NOMESCO Finland
Medical doctor
1.6
6.7
214
1494
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.0
6.7
82
426
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.9
6.7
99
552
A09AA02
ATC
multienzymes (lipase, protease etc.)
4.5
6.7
22
50
R13
ICD-10 Finland
Dysphagia
2.5
6.7
50
207
N04BC05
ATC
pramipexole; oral
2.2
6.7
62
288
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
6.5
6.7
16
25
JAD11
NOMESCO Finland
Laparoscopic repair of incisional hernia
6.0
6.6
17
29
JFG10
NOMESCO Finland
Closure of loop colostomy without resection
7.9
6.6
14
18
WX725
NOMESCO Finland
Noninvasive ventilation
2.8
6.6
40
148
H02AB06
ATC
prednisolone; systemic
1.5
6.6
350
2740
107
Kela drug reimbursment
Pernicious anaemia
3.5
6.5
28
81
L89
ICD-10 Finland
Decubitus ulcer and pressure area
4.2
6.5
23
56
SPAT1255
SPAT
Intravenous administration of medicine
2.4
6.5
53
231
G40.9
ICD-10 Finland
Epilepsy, unspecified
3.0
6.5
34
115
R03BB04
ATC
tiotropium bromide; inhalant
2.0
6.4
84
449
JKA20
NOMESCO Finland
Cholecystectomy
3.2
6.4
32
104
6453
FHL
Radical surgery of hemorrhoids
70.3
6.4
7
*
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
7.5
6.4
14
19
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.4
6.4
54
238
ZXA05
NOMESCO Finland
Left side
1.6
6.4
205
1434
S06.0
ICD-10 Finland
Concussion
2.0
6.4
81
426
A04
ICPC
Weakness/tiredness general
1.8
6.4
100
571
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.0
6.3
33
111
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
6.3
296
2253
UJF02
NOMESCO Finland
Peroral enteroscopy
11.1
6.3
11
10
N06AA12
ATC
doxepin; systemic
2.5
6.3
46
190
JHB30
NOMESCO Finland
Rubber band ligature of haemorrhoids or prolapse of mucosa
3.1
6.3
32
106
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.5
6.3
234
1697
5621A
ICD-9 Finland
Diverticula of intestine, Colon[DIVERTICULOSIS COLI]
+∞
6.3
6
*
4556A
ICD-9 Finland
Haemorrhoids, Unspecified haemorrhoids without mention of complication
+∞
6.3
6
*
Y83.2
ICD-10 Finland
Surgical operation with anastomosis, bypass or graft as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
+∞
6.3
6
*
5621B
ICD-9 Finland
Diverticula of intestine, Colon[DIVERTICULITIS COLI SINE HAEMORRHAGIA]
+∞
6.3
6
*
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.8
6.2
106
621
R31
ICD-10 Finland
Unspecified haematuria
1.9
6.2
88
484
G83.4
ICD-10 Finland
Cauda equina syndrome
26.9
6.2
8
*
JFB33
NOMESCO Finland
Other resection comprising small intestine and colon
26.9
6.2
8
*
326
Kela drug reimbursment
Adalimumab, golimumab, infliximab and ustekinumab (intestinal diseases)
26.9
6.2
8
*
K43.2
ICD-10 Finland
Incisional hernia without obstruction or gangrene
26.9
6.2
8
*
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
3.2
6.2
30
96
G43.9
ICD-10 Finland
Migraine, unspecified
3.0
6.2
33
113
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.7
6.2
122
749
K50.0
ICD-10 Finland
Crohn disease of small intestine
7.7
6.1
13
17
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.5
6.1
272
2046
K46.9
ICD-10 Finland
Unspecified abdominal hernia without obstruction or gangrene
12.6
6.1
10
8
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.3
6.1
55
252
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
8.7
6.1
12
14
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
2.5
6.1
46
192
N05BA06
ATC
lorazepam; systemic, sublingual
2.5
6.1
46
192
RS121
NOMESCO Finland
NA
10.1
6.0
11
11
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.6
6.0
148
966
J10.0
ICD-10 Finland
Influenza with pneumonia, seasonal influenza virus identified
6.1
6.0
15
25
Mortality – FinRegistry
↥Association
Association between endpoint K11_VOLVU and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_VOLVU | 2.403 [2.02, 2.85] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.072 |
During the follow-up period (1.1.1998 — 31.12.2019), 987 out of 2695 females with K11_VOLVU died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| K11_VOLVU | 2.982 [2.43, 3.66] | < 0.001 |
| Birth year | 0.987 [0.98, 1.0] | 0.007 |
During the follow-up period (1.1.1998 — 31.12.2019), 1155 out of 2529 males with K11_VOLVU died.
Mortality risk
Mortality risk for people of age
years, who have K11_VOLVU.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.238% | 0.727% |
| 5 | 1.241% | 3.817% |
| 10 | 3.134% | 8.8% |
| 15 | 5.608% | 16.461% |
| 20 | 9.739% | 26.494% |
Relationships between endpoints
↥Index endpoint: K11_VOLVU – Volvulus
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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