No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleonly females |
293373 |
2. Check conditionsNone |
293373 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
149613 |
4. Check minimum number of eventsNone |
149613 |
5. Include endpointsNone |
149613 |
6. Filter based on genotype QC (FinnGen only) |
149613 |
Control definitions (FinnGen only)
- Control exclude
- O15_DELIVERY
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF5
- Parent code in ICD-10
- O80-O84
- Name in latin
- Partus singularis spontaneus
Single spontaneous delivery
based on the number of shared cases.
Similar with more cases:
Similar with less cases:
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 1102950 | 1102950 | - |
| Only index persons | 1073760 | 1073760 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 31.59 | 31.59 | - |
| Only index persons | 39.47 | 39.47 | - |
| Median age at first event (years) | |||
| Whole population | - | 26.99 | - |
| Only index persons | - | 26.98 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 149613 | 149613 | - |
| Unadjusted period prevalence (%) | 51.00 | 51.00 | - |
| Median age at first event (years) | 27.15 | 27.15 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1899
- Matched controls
- 15414
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
179.8
323.0
360
20
SPAT1197
SPAT
Extensive health check-up of expecting family
97.2
323.0
602
73
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
71.6
323.0
638
108
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
134.3
323.0
501
41
WX307
NOMESCO Finland
Obstetric epidural analgesia
1795.8
323.0
349
*
65000
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
+∞
323.0
1061
*
O80.0
ICD-10 Finland
Spontaneous vertex delivery
+∞
323.0
578
*
SPAT1380
SPAT
Postpartum check-up
642.0
323.0
562
10
SPAT1379
SPAT
Health check-up of pregnant person
70.2
323.0
682
122
Z34.0
ICD-10 Finland
Supervision of normal first pregnancy
84.0
323.0
516
68
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
141.1
323.0
366
26
Z39.2
ICD-10 Finland
Routine postpartum follow-up
467.0
323.0
542
13
W78
ICPC
Pregnancy
42.5
323.0
727
221
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
135.0
313.4
353
26
MAX99
NOMESCO Finland
Assistance to normal delivery
1473.5
295.1
302
*
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
191.9
287.9
316
16
SPAT1399
SPAT
Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.
175.8
279.6
309
17
MA3AE
NOMESCO Finland
Combined first trimester screening
141.7
273.8
308
21
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
225.4
260.8
284
12
O80.8
ICD-10 Finland
Other single spontaneous delivery
+∞
244.5
248
*
W90
ICPC
Uncompl labour/delivery livebirth
573.5
235.5
247
*
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
108.0
228.1
264
23
Z32.1
ICD-10 Finland
Pregnancy confirmed
19.4
218.4
361
184
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
68.5
176.9
217
29
Z37.0
ICD-10 Finland
Single live birth
337.8
176.0
189
5
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
17.0
166.0
287
160
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
149.3
148.8
168
10
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
49.3
144.6
187
34
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
140.3
126.8
144
9
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
78.3
118.5
143
16
OAA11
SPAT
NA
19.6
104.4
170
77
O99.80
ICD-10 Finland
The fear of childbirth
113.3
101.8
118
9
Z34
ICD-10 Finland
Supervision of normal pregnancy
140.4
100.3
114
7
W85
ICPC
Gestational diabetes
57.6
95.3
120
18
OAA12
SPAT
NA
426.3
93.4
100
*
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
+∞
89.2
92
*
SPAT1189
SPAT
Other ultrasound examination during pregnancy
30.7
87.0
124
35
W84
ICPC
Pregnancy high risk
50.2
86.2
111
19
Z3232
NOMESCO Finland
Midwife
15.6
85.1
150
84
O48
ICD-10 Finland
Prolonged pregnancy
747.2
83.3
88
*
SPAT1195
SPAT
Antenatal classes
354.5
77.9
84
*
O47.1
ICD-10 Finland
False labour at or after 37 completed weeks of gestation
+∞
77.4
80
*
MAC40
NOMESCO Finland
Pharmacological induction or advancement of labor
658.5
73.6
78
*
SPAT1200
SPAT
Guidance for breast-feeding and breast care
58.1
70.9
89
13
W29
ICPC
Pregnancy symptom/complaint other
40.7
68.1
91
19
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
305.8
67.2
73
*
O42.9
ICD-10 Finland
Premature rupture of membranes, unspecified
588.2
65.9
70
*
O70.1
ICD-10 Finland
Second degree perineal laceration during delivery
+∞
63.8
66
*
O72.1
ICD-10 Finland
Other immediate postpartum haemorrhage
544.5
61.0
65
*
WX321
NOMESCO Finland
Acute spinal anesthesia for delivery
+∞
60.9
63
*
SPAT1373
SPAT
Combined screening in early pregnancy
63.4
60.5
75
10
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
69.4
60.5
74
9
O21.9
ICD-10 Finland
Vomiting of pregnancy, unspecified
46.4
59.1
77
14
MBC10
NOMESCO Finland
Repair of obstetric laceration of vagina
501.1
56.2
60
*
O26.82
ICD-10 Finland
Exhaustion and fatigue pregnancy-related
71.5
55.8
68
8
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
123.4
51.4
59
*
Z39.1
ICD-10 Finland
Care and examination of lactating mother
457.9
51.4
55
*
Y6099
ICD-8 Finland
Prenatal care and observation
16.4
50.8
87
45
WX234
NOMESCO Finland
Paracervical blockade
30.3
50.7
72
20
O47.9
ICD-10 Finland
False labour, unspecified
230.4
50.0
55
*
WX230
NOMESCO Finland
Plexus blockade of nervus pudendus
+∞
48.2
50
*
63701
ICD-8 Finland
Pre-eclampsia, eclampsia and toxaemia, unspecified, Hypertonia
26.0
48.1
71
23
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
423.5
47.5
51
*
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
217.1
47.1
52
*
OAA10
SPAT
NA
14.1
46.8
85
51
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
208.2
45.2
50
*
O36.8
ICD-10 Finland
Maternal care for other specified fetal problems
389.3
43.7
47
*
O75.6
ICD-10 Finland
Delayed delivery after spontaneous or unspecified rupture of membranes
389.3
43.7
47
*
TMA00
NOMESCO Finland
Episiotomy
389.3
43.7
47
*
Z39.0
ICD-10 Finland
Care and examination immediately after delivery
199.6
43.3
48
*
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
14.3
43.3
78
46
W92
ICPC
Compl labour/ delivery livebirth
85.0
42.9
51
5
WYA40
NOMESCO Finland
Assessment of oral health and treatment needs for family expecting first child
62.0
42.0
52
7
MBC30
NOMESCO Finland
Repair of partial rupture of perineum
+∞
41.4
43
*
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
81.6
41.0
49
5
WX322
NOMESCO Finland
Combined spinal-epidural analgesia in obstetrics
186.8
40.4
45
*
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
2.3
40.1
438
1750
XMA22
NOMESCO Finland
General examination of pregnant woman
93.4
38.3
45
*
OAA70
SPAT
NA
30.0
38.1
54
15
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
2.8
38.0
272
855
O72.0
ICD-10 Finland
Third-stage haemorrhage
338.1
37.9
41
*
MAE00
NOMESCO Finland
Outlet vacuum delivery
+∞
37.6
39
*
O81.4
ICD-10 Finland
Vacuum extractor delivery
329.6
37.0
40
*
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
329.6
37.0
40
*
O23.5
ICD-10 Finland
Infections of the genital tract in pregnancy
+∞
36.6
38
*
W05
ICPC
Pregnancy vomiting/nausea
37.0
36.3
49
11
N61
ICD-10 Finland
Inflammatory disorders of breast
11.1
34.8
70
53
O14.9
ICD-10 Finland
Pre-eclampsia, unspecified
+∞
34.7
36
*
O26.88
ICD-10 Finland
Other specified pregnancy-related conditions
84.9
34.5
41
*
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
29.1
34.4
49
14
O35.8
ICD-10 Finland
Maternal care for other (suspected) fetal abnormality and damage
304.2
34.1
37
*
O21
ICD-10 Finland
Excessive vomiting in pregnancy
40.5
33.2
44
9
Z36.8
ICD-10 Finland
Other antenatal screening
44.6
33.0
43
8
WZB00
SPAT
NA
0.3
32.0
102
2204
O28.8
ICD-10 Finland
Other abnormal findings on antenatal screening of mother
148.7
31.9
36
*
SPAT1375
SPAT
Structural ultrasound screening, weeks 18+0-21+6
102.0
31.8
37
*
MA5AE
SPAT
NA
+∞
31.8
33
*
Z35.6
ICD-10 Finland
Supervision of very young primigravida
+∞
31.8
33
*
O72.2
ICD-10 Finland
Delayed and secondary postpartum haemorrhage
278.8
31.2
34
*
Z35.7
ICD-10 Finland
Supervision of high-risk pregnancy due to social problems
76.5
30.8
37
*
O68.0
ICD-10 Finland
Labour and delivery complicated by fetal heart rate anomaly
270.3
30.3
33
*
65006
ICD-8 Finland
Delivery without mention of complication, Complete or incomplete breech presentation
+∞
28.9
30
*
SPAT1249
SPAT
Treatment-related counselling outside office
1.7
28.4
931
5492
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
57.9
28.1
35
5
63499
ICD-8 Finland
Other complications of pregnancy, Other
27.6
27.8
40
12
SPAT1391
SPAT
Counselling and guidance related to family situation
12.4
27.5
52
35
O26.7
ICD-10 Finland
Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
88.0
27.1
32
*
MAC02
NOMESCO Finland
Rupture of aminiotic membrane for advancement of labor
+∞
26.9
28
*
O04.9
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
3.8
26.8
121
269
OAB30
SPAT
NA
66.0
26.2
32
*
O32.1
ICD-10 Finland
Maternal care for breech presentation
85.2
26.2
31
*
63703
ICD-8 Finland
Pre-eclampsia, eclampsia and toxaemia, unspecified, Prae-eclampsia levis
22.1
26.2
40
15
O60
ICD-10 Finland
Preterm labour and delivery
63.9
25.3
31
*
MA3AE
SPAT
NA
222.8
24.6
27
*
LCH11
NOMESCO Finland
Pharmacologic abortion
3.9
24.2
105
226
O36.9
ICD-10 Finland
Maternal care for fetal problem, unspecified
+∞
24.1
25
*
O47
ICD-10 Finland
False labour
+∞
24.1
25
*
W27
ICPC
Fear of complications of pregnancy
111.0
23.5
27
*
WX740
NOMESCO Finland
Nitrogen oxide therapy
+∞
23.1
24
*
ZYC02
SPAT
NA
0.2
23.0
28
994
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
9.2
22.9
50
45
O24.9
ICD-10 Finland
Diabetes mellitus in pregnancy, unspecified
205.5
22.7
25
*
FM1QE
NOMESCO Finland
Extensive ultrasound of fetal heart
74.1
22.5
27
*
O91.2
ICD-10 Finland
Nonpurulent mastitis associated with childbirth
74.1
22.5
27
*
O41.0
ICD-10 Finland
Oligohydramnios
+∞
22.1
23
*
64399
ICD-8 Finland
Spontaneous abortion, Without mention of sepsis or toxaemia
5.1
21.8
72
118
SPAT1381
SPAT
Extensive health check-up at 4 months of age
197.1
21.7
24
*
SPAT1196
SPAT
Monitoring of normal pregnancy
55.4
21.7
27
*
63497
ICD-8 Finland
Other complications of pregnancy, Partus prematurus imminens, alibi non classificabilis
20.9
21.4
33
13
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
3.1
21.3
129
359
MAC96
NOMESCO Finland
Other induction or advancement of labour
+∞
21.2
22
*
O26.6
ICD-10 Finland
Liver disorders in pregnancy, childbirth and the puerperium
+∞
21.2
22
*
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
+∞
21.2
22
*
Z35
ICD-10 Finland
Supervision of high-risk pregnancy
68.5
20.7
25
*
TMW99
NOMESCO Finland
Other minor surgical procedure in obstetrics
+∞
20.2
21
*
O86.1
ICD-10 Finland
Other infection of genital tract following delivery
+∞
19.2
20
*
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
+∞
19.2
20
*
OAA41
SPAT
NA
7.8
19.2
46
49
SPAT1393
SPAT
Guidance to support interaction between parent and child
49.3
19.0
24
*
Z36.9
ICD-10 Finland
Antenatal screening, unspecified
90.2
18.8
22
*
O02.1
ICD-10 Finland
Missed abortion
12.7
18.5
34
22
O42.0
ICD-10 Finland
Premature rupture of membranes, onset of labour within 24 hours
163.9
18.0
20
*
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
163.9
18.0
20
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.7
18.0
448
2358
SPAT1283
SPAT
Restricted health certificate
1.7
17.9
439
2301
OAB42
SPAT
NA
0.4
16.8
69
1361
63230
ICD-8 Finland
Haemorrhage of pregnancy, Threatened abortion
9.6
16.7
35
30
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.7
16.7
460
2485
O70.0
ICD-10 Finland
First degree perineal laceration during delivery
+∞
16.3
17
*
Z32
ICD-10 Finland
Pregnancy examination and test
43.0
16.3
21
*
O21.0
ICD-10 Finland
Mild hyperemesis gravidarum
77.8
16.0
19
*
Z87.5
ICD-10 Finland
Personal history of complications of pregnancy, childbirth and the puerperium
77.8
16.0
19
*
OAB39
SPAT
NA
0.3
15.7
48
1076
O46.9
ICD-10 Finland
Antepartum haemorrhage, unspecified
+∞
15.4
16
*
65007
ICD-8 Finland
Delivery without mention of complication, Multiple pregnancy, all presentations
+∞
15.4
16
*
O42.1
ICD-10 Finland
Premature rupture of membranes, onset of labour after 24 hours
139.1
15.1
17
*
Z86.4
ICD-10 Finland
Personal history of psychoactive substance abuse
32.7
14.7
20
5
W79
ICPC
Unwanted pregnancy
4.0
14.5
60
125
Z39
ICD-10 Finland
Postpartum care and examination
+∞
14.4
15
*
O61.8
ICD-10 Finland
Other failed induction of labour
+∞
14.4
15
*
O86.0
ICD-10 Finland
Infection of obstetric surgical wound
+∞
14.4
15
*
IHZ05
SPAT
NA
0.3
14.2
27
753
Y1901
ICD-8 Finland
Other studies, Pregnancy study
11.9
13.9
26
18
W01
ICPC
Question of pregnancy
4.3
13.9
53
103
SPAT1192
SPAT
Gynaecological examination
1.8
13.3
251
1203
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
65.5
13.3
16
*
O35.1
ICD-10 Finland
Maternal care for (suspected) chromosomal abnormality in fetus
122.6
13.3
15
*
SPAT1187
SPAT
General ultrasound examination in early pregnancy
34.7
12.8
17
*
MBA30
NOMESCO Finland
Manual removal of placenta from delivered uterus
+∞
12.5
13
*
O35.9
ICD-10 Finland
Maternal care for (suspected) fetal abnormality and damage, unspecified
+∞
12.5
13
*
O80.9
ICD-10 Finland
Single spontaneous delivery, unspecified
+∞
12.5
13
*
MBC20
NOMESCO Finland
Repair of obstetric laceration of vulva
+∞
12.5
13
*
MBA04
NOMESCO Finland
Curettage of uterus after delivery
+∞
12.5
13
*
O40
ICD-10 Finland
Polyhydramnios
+∞
12.5
13
*
MBA40
NOMESCO Finland
Pharmacological evacuation of uterus after abortion
10.9
12.4
24
18
W94
ICPC
Puerperal mastitis
61.4
12.4
15
*
O26.9
ICD-10 Finland
Pregnancy-related condition, unspecified
114.4
12.3
14
*
SPAT1357
SPAT
Monitoring of problem during pregnancy
114.4
12.3
14
*
Z76.0
ICD-10 Finland
Issue of repeat prescription
0.5
12.2
126
1825
63702
ICD-8 Finland
Pre-eclampsia, eclampsia and toxaemia, unspecified, Oedema
27.8
12.2
17
5
WZC00
SPAT
NA
0.4
12.1
58
1084
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.4
12.1
803
5218
SPAT1263
SPAT
Sampling
1.4
11.7
972
6568
OAB36
SPAT
NA
0.2
11.7
9
420
63496
ICD-8 Finland
Other complications of pregnancy, Labores inhibiti
40.9
11.6
15
*
65004
ICD-8 Finland
Delivery without mention of complication, Occipital presentation, posterior position
+∞
11.5
12
*
SPAT1246
SPAT
Screening of depression or other psychiatric problem
2.0
11.3
154
657
SGA01
NOMESCO Finland
Tooth opening as first aid
1.9
11.0
161
706
O20.8
ICD-10 Finland
Other haemorrhage in early pregnancy
38.1
10.8
14
*
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
3.7
10.7
47
105
SPAT1364
SPAT
Health check-up performed during second study year in students of upper secondary schools, vocational schools etc.
0.6
10.6
186
2361
O71.4
ICD-10 Finland
Obstetric high vaginal laceration
+∞
10.6
11
*
MBC33
NOMESCO Finland
Repair of complete rupture of perineum
+∞
10.6
11
*
O41.8
ICD-10 Finland
Other specified disorders of amniotic fluid and membranes
+∞
10.6
11
*
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
53.0
10.6
13
*
MBA96
NOMESCO Finland
Other removal of retained products of conception after delivery or abortion
18.7
10.3
16
7
SPAT1128
SPAT
Instruction of pelvic floor / sphincter exercises
9.6
10.3
21
18
O03.4
ICD-10 Finland
Spontaneous abortion, Incomplete, without complication
11.1
10.0
19
14
WX306
NOMESCO Finland
Lumbar epidural anesthesy
2.6
10.0
76
246
MA2AE
SPAT
NA
16.3
9.9
16
8
63500
ICD-8 Finland
Urinary infections arising during pregnancy and the puerperium, Pyelonephritis
35.4
9.9
13
*
SPAT1382
SPAT
Extensive health check-up at 18 months of age
48.9
9.7
12
*
Z64.0
ICD-10 Finland
Problems related to unwanted pregnancy
4.4
9.7
35
66
TQW30
NOMESCO Finland
Acupuncture
+∞
9.6
10
*
SPAT1301
SPAT
No procedures
1.4
9.6
781
5194
W99
ICPC
Disorder of pregn/delivery other
89.7
9.5
11
*
OAA48
SPAT
NA
17.5
9.5
15
7
QXA70
SPAT
NA
0.1
9.4
5
301
WYA50
NOMESCO Finland
Student oral health check consistent with decree to assess need for oral health guidance and services
0.5
9.0
73
1142
O99.5
ICD-10 Finland
Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
32.6
9.0
12
*
K02.1
ICD-10 Finland
Caries of dentine
1.3
8.9
931
6418
D10BA01
ATC
isotretinoin; oral
0.4
8.7
32
662
63494
ICD-8 Finland
Other complications of pregnancy, Insufficientia cervicis
16.3
8.7
14
7
O20.0
ICD-10 Finland
Threatened abortion
16.3
8.7
14
7
O70.21
ICD-10 Finland
III degree perineal tear involving less than one half of external anal sphincter thickness torn during childbirth
+∞
8.6
9
*
Z36.4
ICD-10 Finland
Antenatal screening for fetal growth retardation using ultrasound and other physical methods
+∞
8.6
9
*
O82.0
ICD-10 Finland
Delivery by elective caesarean section
+∞
8.6
9
*
O80.1
ICD-10 Finland
Spontaneous breech delivery
+∞
8.6
9
*
MAA00
NOMESCO Finland
Amniocentesis
+∞
8.6
9
*
K04.08
ICD-10 Finland
Other specified pulpit
2.3
8.6
77
275
O14.0
ICD-10 Finland
Mild to moderate pre-eclampsia
81.5
8.6
10
*
R3110
NOMESCO Finland
Psychosocial training
17.7
8.3
13
6
WZA10
SPAT
NA
0.2
8.2
9
339
IHZ02
SPAT
NA
0.3
8.2
14
413
O28.3
ICD-10 Finland
Abnormal ultrasonic finding on antenatal screening of mother
29.9
8.1
11
*
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
29.9
8.1
11
*
W82
ICPC
Abortion spontaneous
12.7
8.0
14
9
W03
ICPC
Antepartum bleeding
15.2
7.9
13
7
WX290
NOMESCO Finland
Other blockade of nerve
1.3
7.8
677
4511
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
7.7
738
4986
FM1NE
NOMESCO Finland
Ultrasound examination of fetal heart
73.4
7.7
9
*
O63.1
ICD-10 Finland
Prolonged second stage (of labour)
73.4
7.7
9
*
O85
ICD-10 Finland
Puerperal sepsis
+∞
7.7
8
*
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
+∞
7.7
8
*
O12.1
ICD-10 Finland
Gestational proteinuria
+∞
7.7
8
*
SPAT1238
SPAT
Brief therapy
3.1
7.6
41
110
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.5
7.6
295
1702
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.3
7.5
649
4312
64594
ICD-8 Finland
Other abortion, Retentio ovi (partialis)
4.8
7.4
24
41
SGC10
NOMESCO Finland
Covering pulpa of tooth
1.7
7.4
143
691
O04.1
ICD-10 Finland
Medical abortion, incomplete, complicated by delayed or excessive haemorrhage
8.2
7.3
16
16
SPAT1312
SPAT
General health counselling
1.3
7.3
820
5652
Y6199
ICD-8 Finland
Postpartum observation, without abnormal symptoms
27.2
7.3
10
*
N02BE01
ATC
paracetamol; systemic, rectal
1.4
7.2
1508
11361
K04.0
ICD-10 Finland
Pulpitis
1.9
7.1
96
412
R74
ICPC
Upper respiratory infection acute
1.3
7.1
553
3610
XMA20
NOMESCO Finland
Early examination of pregnancy
36.6
7.0
9
*
M54.5
ICD-10 Finland
Low back pain
1.3
7.0
532
3459
ZYC01
SPAT
NA
0.6
6.9
99
1324
OAB44
SPAT
NA
0.5
6.8
63
949
63495
ICD-8 Finland
Other complications of pregnancy, Effluxus liquoris amnii praetemporarius
65.2
6.8
8
*
W19
ICPC
Lactation symptom/complaint
65.2
6.8
8
*
ZYC05
SPAT
NA
0.3
6.8
16
399
SGC00
NOMESCO Finland
Local medication of root channels of tooth
1.9
6.7
100
442
W18
ICPC
Post-partum symptom/complaint other
+∞
6.7
7
*
IBC98
NOMESCO Finland
Other child protection assessment
+∞
6.7
7
*
O23.0
ICD-10 Finland
Infections of kidney in pregnancy
+∞
6.7
7
*
O73.0
ICD-10 Finland
Retained placenta without haemorrhage
+∞
6.7
7
*
O68.1
ICD-10 Finland
Labour and delivery complicated by meconium in amniotic fluid
+∞
6.7
7
*
O75.0
ICD-10 Finland
Maternal distress during labour and delivery
+∞
6.7
7
*
N81.1
ICD-10 Finland
Cystocele
1.7
6.7
148
746
J01AA04
ATC
lymecycline; systemic
0.6
6.6
95
1270
OAB38
SPAT
NA
0.4
6.5
26
521
KAY20
NOMESCO Finland
NA
0.3
6.5
15
381
SPAT1392
SPAT
Counselling and guidance related to couple relationship
5.0
6.5
20
33
21899
ICD-8 Finland
Uterine fibroma
0.6
6.5
101
1321
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.4
6.5
401
2519
63501
ICD-8 Finland
Urinary infections arising during pregnancy and the puerperium, Pyelitis et pyelocystitis
24.4
6.4
9
*
SPAT1310
SPAT
Counselling related to known health issue
1.3
6.4
736
5063
63700
ICD-8 Finland
Pre-eclampsia, eclampsia and toxaemia, unspecified, Albuminuria (proteinuria)
12.8
6.4
11
7
67000
ICD-8 Finland
Sepsis of childbirth and the puerperium, Endometritis
16.3
6.4
10
5
-2
ICD-10 Finland
NA
0.4
6.4
22
465
D10
ICPC
Vomiting
1.7
6.3
130
640
K04.1
ICD-10 Finland
Necrosis of pulp
1.9
6.3
95
424
N71.9
ICD-10 Finland
Inflammatory disease of uterus, unspecified
6.2
6.3
16
21
SPAT1307
SPAT
Psychosocial counselling and guidance
1.5
6.2
243
1401
78950
ICD-8 Finland
Abnormal urinary constituents of unspecified cause, Glycosuria
32.5
6.1
8
*
O64.0
ICD-10 Finland
Obstructed labour due to incomplete rotation of fetal head
32.5
6.1
8
*
J03.9
ICD-10 Finland
Acute tonsillitis, unspecified
1.6
6.0
135
683
Mortality – FinRegistry
↥Association
Association between endpoint O15_DELIV_SPONT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| O15_DELIV_SPONT | 0.488 [0.43, 0.55] | < 0.001 |
| Birth year | 0.995 [0.99, 1.0] | 0.254 |
During the follow-up period (1.1.1998 — 31.12.2019), 1657 out of 398394 females with O15_DELIV_SPONT died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have O15_DELIV_SPONT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.055% | No data |
| 5 | 0.303% | No data |
| 10 | 0.715% | No data |
| 15 | 1.463% | No data |
| 20 | 2.616% | No data |
Relationships between endpoints
↥Index endpoint: O15_DELIV_SPONT – Single spontaneous delivery
GWS hits: 6
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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