Retained placenta and membranes, without haemorrhage

O15_RETAINED_PLAC_MEMB_NO_HEAMORRH

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

only females

293373

2. Check conditions

None

293373

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 O73
  • Hospital discharge: ICD-9 667
  • Hospital discharge: ICD-8 652
  • Cause of death: ICD-10 O73
  • Cause of death: ICD-9 667
  • Cause of death: ICD-8 652

2 out of 7 registries used, show all original rules.

5155

4. Check minimum number of events

None

5155

5. Include endpoints

None

5155

6. Filter based on genotype QC (FinnGen only)

5155

Control definitions (FinnGen only)

Control exclude
O15_COMPLIC_LAB_DELIV

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5
Parent code in ICD-10
O60-O75
Name in latin
Retentio placentae et membranarum sine haemorrhagia

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 36337 36337 -
Only index persons 35381 35381 -
Unadjusted period prevalence (%)
Whole population 1.04 1.04 -
Only index persons 1.30 1.30 -
Median age at first event (years)
Whole population - 28.88 -
Only index persons - 28.88 -

-FinnGen-

Key figures

All Female Male
Number of individuals 5155 5155 -
Unadjusted period prevalence (%) 1.76 1.76 -
Median age at first event (years) 29.13 29.13 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
4690
Matched controls
46900
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
O73.0
ICD-10 Finland
Retained placenta without haemorrhage
+∞
323.0
1061
*
MBA30
NOMESCO Finland
Manual removal of placenta from delivered uterus
450.4
323.0
977
27
6670A
ICD-9 Finland
Retained placenta or membranes, without haemorrhage, Retained placenta without haemorrhage
+∞
323.0
441
*
65200
ICD-8 Finland
Occipital presentation
+∞
323.0
813
*
8832
FHL
Manual placenta removal and associated scraping
512.1
323.0
422
9
65210
ICD-8 Finland
Occipital presentation
+∞
323.0
717
*
6671A
ICD-9 Finland
Retained placenta or membranes, without haemorrhage, Retained portions of placenta or membranes, without haemorrhage
+∞
323.0
499
*
O73.1
ICD-10 Finland
Retained portions of placenta and membranes, without haemorrhage
+∞
323.0
843
*
O72.0
ICD-10 Finland
Third-stage haemorrhage
+∞
313.1
297
*
65220
ICD-8 Finland
Occipital presentation
+∞
304.5
289
*
O72.2
ICD-10 Finland
Delayed and secondary postpartum haemorrhage
1352.4
264.9
256
*
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
8.6
222.5
512
658
O81.4
ICD-10 Finland
Vacuum extractor delivery
24.6
208.2
300
130
O68.0
ICD-10 Finland
Labour and delivery complicated by fetal heart rate anomaly
+∞
205.7
196
*
O60
ICD-10 Finland
Preterm labour and delivery
1873.0
197.1
190
*
8831
FHL
Uterine exploration and / or scraping or suction emptying (ad 24 hours)
112.1
196.9
214
20
MAE00
NOMESCO Finland
Outlet vacuum delivery
25.2
189.6
271
114
MBA04
NOMESCO Finland
Curettage of uterus after delivery
481.6
187.6
186
*
O72.1
ICD-10 Finland
Other immediate postpartum haemorrhage
+∞
168.8
161
*
63497
ICD-8 Finland
Other complications of pregnancy, Partus prematurus imminens, alibi non classificabilis
+∞
156.1
149
*
O70.1
ICD-10 Finland
Second degree perineal laceration during delivery
1524.2
149.8
145
*
8841
FHL
Uterine emptying and scraping (ad 6 weeks)
70.0
135.6
156
23
MBC30
NOMESCO Finland
Repair of partial rupture of perineum
20.2
132.3
202
104
O63.1
ICD-10 Finland
Prolonged second stage (of labour)
+∞
128.7
123
*
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
2.7
113.9
887
3681
Z39.2
ICD-10 Finland
Routine postpartum follow-up
2.9
109.2
759
2926
ZXD05
NOMESCO Finland
Urgent procedure
2.2
108.1
1471
8118
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
2.2
103.2
1327
7111
6440B
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS]
+∞
92.0
88
*
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
2.4
91.4
907
4252
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
2.9
91.4
608
2260
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
2.4
87.2
894
4247
SPAT1197
SPAT
Extensive health check-up of expecting family
2.7
86.5
684
2823
O70.0
ICD-10 Finland
First degree perineal laceration during delivery
+∞
85.7
82
*
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
2.8
75.3
551
2161
O64.0
ICD-10 Finland
Obstructed labour due to incomplete rotation of fetal head
+∞
73.1
70
*
W78
ICPC
Pregnancy
2.4
72.9
731
3404
SPAT1379
SPAT
Health check-up of pregnant person
2.6
71.1
572
2367
65300
ICD-8 Finland
Occipital presentation
+∞
67.9
65
*
6441A
ICD-9 Finland
Early or threatened labour, Other threatened labour
+∞
66.8
64
*
MBC20
NOMESCO Finland
Repair of obstetric laceration of vulva
59.4
64.8
76
13
WX307
NOMESCO Finland
Obstetric epidural analgesia
2.9
64.6
433
1601
6522B
ICD-9 Finland
Malposition and malpresentation of foetus, Breech presentation without mention of version[PRAESENTATIO CLUNIUM,SYNNYTYKSEN AIKANA]
+∞
63.7
61
*
SPAT1380
SPAT
Postpartum check-up
2.7
62.0
479
1927
Z32.1
ICD-10 Finland
Pregnancy confirmed
2.4
61.3
555
2438
O80.8
ICD-10 Finland
Other single spontaneous delivery
3.6
58.8
287
844
6660A
ICD-9 Finland
Postpartum haemorrhage, Third-stage haemorrhage[HAEMORRHAGIA POST PARTUM STADII III]
+∞
58.4
56
*
MBA96
NOMESCO Finland
Other removal of retained products of conception after delivery or abortion
4.9
58.2
198
416
O80.0
ICD-10 Finland
Spontaneous vertex delivery
1.7
57.0
1631
11170
Z34.0
ICD-10 Finland
Supervision of normal first pregnancy
2.2
55.4
649
3221
MBC10
NOMESCO Finland
Repair of obstetric laceration of vagina
8.2
53.8
123
153
O64.1
ICD-10 Finland
Obstructed labour due to breech presentation
534.0
53.6
53
*
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
2.5
53.0
459
1964
WX306
NOMESCO Finland
Lumbar epidural anesthesy
2.7
50.9
387
1538
6660B
ICD-9 Finland
Postpartum haemorrhage, Third-stage haemorrhage[HAEMORRHAGIA POST PARTUM CUM RETENT PLAC TOTALI]
+∞
50.1
48
*
SPAT1196
SPAT
Monitoring of normal pregnancy
2.6
49.4
395
1615
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
2.6
48.7
378
1520
O61.0
ICD-10 Finland
Failed medical induction of labour
+∞
48.0
46
*
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
4.5
47.9
178
410
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
2.2
46.7
544
2682
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
3.8
46.4
206
559
6660C
ICD-9 Finland
Postpartum haemorrhage, Third-stage haemorrhage[HAEMORRHAGIA POST PARTUM CUM RETENT PLAC PARTIALI]
+∞
45.9
44
*
O75.6
ICD-10 Finland
Delayed delivery after spontaneous or unspecified rupture of membranes
+∞
44.9
43
*
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
5.8
44.1
129
228
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
2.4
44.0
418
1867
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
2.8
43.3
303
1144
O99.80
ICD-10 Finland
The fear of childbirth
3.0
43.1
258
879
O63.0
ICD-10 Finland
Prolonged first stage (of labour)
+∞
42.8
41
*
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
3.7
42.4
193
536
G02AB01
ATC
methylergometrine; systemic
12.4
41.8
76
62
O20.0
ICD-10 Finland
Threatened abortion
3.6
40.3
193
558
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
2.1
39.9
493
2485
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
3.4
39.4
203
622
O75.0
ICD-10 Finland
Maternal distress during labour and delivery
+∞
38.6
37
*
6611B
ICD-9 Finland
Abnormality of forces of labour, Secondary uterine inertia
+∞
38.6
37
*
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
2.0
38.3
562
3031
Z37.0
ICD-10 Finland
Single live birth
2.0
37.0
507
2660
W84
ICPC
Pregnancy high risk
3.5
37.0
180
528
65310
ICD-8 Finland
Occipital presentation
+∞
36.5
35
*
8502
FHL
Evacuation and abrasion
2.4
35.3
326
1430
O86.1
ICD-10 Finland
Other infection of genital tract following delivery
9.6
34.9
72
76
O02.1
ICD-10 Finland
Missed abortion
2.3
32.6
324
1473
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
2.1
32.0
410
2089
O85
ICD-10 Finland
Puerperal sepsis
6.2
31.6
86
140
O68.8
ICD-10 Finland
Labour and delivery complicated by other evidence of fetal stress
+∞
31.3
30
*
XMA22
NOMESCO Finland
General examination of pregnant woman
2.2
30.8
325
1523
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
2.2
30.4
336
1606
SPAT1189
SPAT
Other ultrasound examination during pregnancy
3.1
30.3
176
589
65290
ICD-8 Finland
Occipital presentation
+∞
30.2
29
*
O62.1
ICD-10 Finland
Secondary uterine inertia
+∞
30.2
29
*
W92
ICPC
Compl labour/ delivery livebirth
5.6
30.1
89
161
63230
ICD-8 Finland
Haemorrhage of pregnancy, Threatened abortion
2.8
29.6
192
692
MAC96
NOMESCO Finland
Other induction or advancement of labour
3.4
28.8
146
444
MAX99
NOMESCO Finland
Assistance to normal delivery
1.9
28.7
472
2642
MAC40
NOMESCO Finland
Pharmacological induction or advancement of labor
5.3
28.0
87
167
MBC00
NOMESCO Finland
Repair of obstetric laceration of cervix uteri
145.9
27.6
29
*
Z3232
NOMESCO Finland
Midwife
1.9
26.9
433
2402
6622B
ICD-9 Finland
Long labour, Prolonged second stage
+∞
26.1
25
*
O71.4
ICD-10 Finland
Obstetric high vaginal laceration
+∞
26.1
25
*
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.4
25.6
1727
13714
SPAT1357
SPAT
Monitoring of problem during pregnancy
3.1
25.5
146
484
O68.2
ICD-10 Finland
Labour and delivery complicated by fetal heart rate anomaly with meconium in amniotic fluid
+∞
25.0
24
*
O71.3
ICD-10 Finland
Obstetric laceration of cervix
+∞
25.0
24
*
Z39.1
ICD-10 Finland
Care and examination of lactating mother
3.8
25.0
109
294
O35.8
ICD-10 Finland
Maternal care for other (suspected) fetal abnormality and damage
3.7
24.5
110
304
O41.1
ICD-10 Finland
Infection of amniotic sac and membranes
9.5
24.4
50
53
O68.1
ICD-10 Finland
Labour and delivery complicated by meconium in amniotic fluid
+∞
24.0
23
*
WX321
NOMESCO Finland
Acute spinal anesthesia for delivery
2.4
23.8
203
855
MBA20
NOMESCO Finland
Expression of placenta
6.6
23.7
61
93
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.8
23.6
467
2771
28000
ICD-8 Finland
Iron deficiency anaemias, Posthaemorrhagica
8.3
23.5
52
63
64399
ICD-8 Finland
Spontaneous abortion, Without mention of sepsis or toxaemia
2.2
23.3
244
1140
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
2.3
23.0
224
1010
65206
ICD-8 Finland
Complete or incomplete breech presentation
+∞
22.9
22
*
6400A
ICD-9 Finland
Haemorrhage in early pregnancy, Threatened abortion
4.1
22.9
90
222
O42.9
ICD-10 Finland
Premature rupture of membranes, unspecified
2.7
22.8
156
581
8801
FHL
Suction cup delivery
4.0
22.2
91
233
O32.1
ICD-10 Finland
Maternal care for breech presentation
2.3
22.1
204
898
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
3.7
22.0
97
265
WX600
NOMESCO Finland
Single shot through catheter
3.7
22.0
96
260
O47.1
ICD-10 Finland
False labour at or after 37 completed weeks of gestation
2.4
22.0
189
802
6653B
ICD-9 Finland
Other obstetrical trauma, Laceration of cervix
+∞
21.9
21
*
O68.3
ICD-10 Finland
Labour and delivery complicated by biochemical evidence of fetal stress
+∞
21.9
21
*
O48
ICD-10 Finland
Prolonged pregnancy
2.6
21.6
161
633
SPAT1200
SPAT
Guidance for breast-feeding and breast care
3.0
21.3
123
412
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
2.6
21.2
161
638
ULC02
NOMESCO Finland
Hysteroscopy
1.9
21.1
337
1859
O69.1
ICD-10 Finland
Labour and delivery complicated by cord around neck, with compression
+∞
20.8
20
*
65201
ICD-8 Finland
Face and brow presentation
+∞
20.8
20
*
Z35.4
ICD-10 Finland
Supervision of pregnancy with grand multiparity
5.8
20.8
59
103
W85
ICPC
Gestational diabetes
2.6
20.7
158
629
MA3AE
NOMESCO Finland
Combined first trimester screening
2.5
20.6
164
667
SPAT1399
SPAT
Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.
2.6
20.5
155
615
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
2.3
20.4
185
807
Z87.5
ICD-10 Finland
Personal history of complications of pregnancy, childbirth and the puerperium
5.8
19.9
56
97
O70.2
ICD-10 Finland
Third degree perineal laceration during delivery
+∞
19.8
19
*
O67.9
ICD-10 Finland
Intrapartum haemorrhage, unspecified
+∞
19.8
19
*
67790
ICD-8 Finland
Other and unspecified complications of the puerperium, Retentio placentae partialis
7.5
19.6
46
62
O34.3
ICD-10 Finland
Maternal care for cervical incompetence
9.0
19.5
41
46
P01AB01
ATC
metronidazole; oral, rectal
1.3
19.2
1951
16334
SPAT1263
SPAT
Sampling
1.3
19.1
1732
14247
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
2.4
18.9
161
681
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
2.6
18.8
140
551
65207
ICD-8 Finland
Multiple pregnancy, all presentations
+∞
18.8
18
*
O64.8
ICD-10 Finland
Obstructed labour due to other malposition and malpresentation
+∞
18.8
18
*
6654B
ICD-9 Finland
Other obstetrical trauma, High vaginal laceration
+∞
18.8
18
*
SPAT1324
SPAT
Screening procedure
1.4
18.6
1231
9612
SPAT1195
SPAT
Antenatal classes
2.8
18.5
123
453
MBA05
NOMESCO Finland
Curettage of uterus after abortion
4.7
18.4
62
132
Z30.2
ICD-10 Finland
Sterilization
1.6
18.2
574
3857
O46.9
ICD-10 Finland
Antepartum haemorrhage, unspecified
3.1
17.9
100
330
O24.9
ICD-10 Finland
Diabetes mellitus in pregnancy, unspecified
3.2
17.9
96
308
8833
FHL
Correction of II ^ 0 or III ^ 0 perineumrupth or vaginal rupture
11.9
17.8
32
27
8834
FHL
Kerviksrupure repair
+∞
17.7
17
*
6700A
ICD-9 Finland
Major puerperal infection
5.0
17.6
56
113
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
3.7
17.2
75
205
Z34
ICD-10 Finland
Supervision of normal pregnancy
2.1
17.0
190
916
SPAT1193
SPAT
Pap smear
1.5
16.9
590
4057
TMA00
NOMESCO Finland
Episiotomy
2.5
16.8
134
549
O23.5
ICD-10 Finland
Infections of the genital tract in pregnancy
4.8
16.7
55
115
6522A
ICD-9 Finland
Malposition and malpresentation of foetus, Breech presentation without mention of version[PRAESENTATIO CLUNIUM,RASKAUDEN AIKANA]
+∞
16.7
16
*
6661A
ICD-9 Finland
Postpartum haemorrhage, Other immediate postpartum haemorrhage[HAEMORRHAGIA POST PARTUM ATONICA UTERI]
+∞
16.7
16
*
O82.11
ICD-10 Finland
Childbirth with an emergency caesarean section in an emergency
12.8
16.1
28
22
V252A
ICD-9 Finland
Contraceptive management, Sterilisation
1.5
16.1
507
3404
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
16.1
1092
8528
O86.8
ICD-10 Finland
Other specified puerperal infections
11.7
16.0
29
25
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
1.7
16.0
363
2241
O41.0
ICD-10 Finland
Oligohydramnios
2.8
15.4
99
356
O14.9
ICD-10 Finland
Pre-eclampsia, unspecified
4.1
15.4
60
149
6440A
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS IMMINENS]
2.6
15.2
112
440
N85.6
ICD-10 Finland
Intrauterine synechiae
16.1
15.2
24
15
W29
ICPC
Pregnancy symptom/complaint other
2.6
15.0
109
425
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
3.1
15.0
83
274
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
14.8
1607
13424
Y1901
ICD-8 Finland
Other studies, Pregnancy study
3.3
14.7
74
228
N81.6
ICD-10 Finland
Rectocele
1.7
14.6
330
2029
O44.1
ICD-10 Finland
Placenta praevia with haemorrhage
5.4
14.6
43
80
6535B
ICD-9 Finland
Disproportion, Unusually large foetus causing disproportion[EPÄTAVALLISEN ISO SIKIÖ (YLI 4500 G), SYNN AIKANA]
+∞
14.6
14
*
65696
ICD-8 Finland
Delivery complicated by malpresentation of foetus, Complete or incomplete breech presentation
+∞
14.6
14
*
66030
ICD-8 Finland
Occipital presentation
+∞
14.6
14
*
Z36.8
ICD-10 Finland
Other antenatal screening
2.7
14.2
94
348
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
2.3
14.0
123
533
LCA10
NOMESCO Finland
Curettage of body of uterus
2.1
13.8
162
800
N71.0
ICD-10 Finland
Acute inflammatory disease of uterus
2.1
13.8
154
741
8221
FHL
Sterilization of the laparotomy pathway
2.1
13.7
165
819
6534B
ICD-9 Finland
Disproportion, Foetopelvic disproportion[DISPROPORTIO FOETOPELVICA,SYNNYTYKSEN AIKANA]
+∞
13.5
13
*
O66.0
ICD-10 Finland
Obstructed labour due to shoulder dystocia
+∞
13.5
13
*
TMW99
NOMESCO Finland
Other minor surgical procedure in obstetrics
4.9
13.5
43
88
8811
FHL
Cesarean section
2.0
13.4
176
906
ZXD00
NOMESCO Finland
Emergency procedure
2.6
13.4
99
389
O26.88
ICD-10 Finland
Other specified pregnancy-related conditions
3.2
13.4
69
217
O21.9
ICD-10 Finland
Vomiting of pregnancy, unspecified
3.5
13.4
62
180
63496
ICD-8 Finland
Other complications of pregnancy, Labores inhibiti
2.8
13.4
84
302
Y6099
ICD-8 Finland
Prenatal care and observation
1.7
13.3
260
1538
67000
ICD-8 Finland
Sepsis of childbirth and the puerperium, Endometritis
2.8
13.2
86
313
Z39.0
ICD-10 Finland
Care and examination immediately after delivery
3.8
13.1
54
142
6340A
ICD-9 Finland
Spontaneous abortion, Complicated by genital tract and pelvic infection
2.2
13.0
134
624
O47.9
ICD-10 Finland
False labour, unspecified
3.0
13.0
72
239
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
2.4
13.0
107
449
WX234
NOMESCO Finland
Paracervical blockade
2.1
12.8
143
693
6610B
ICD-9 Finland
Abnormality of forces of labour, Primary uterine inertia
+∞
12.5
12
*
O62.0
ICD-10 Finland
Primary inadequate contractions
+∞
12.5
12
*
65204
ICD-8 Finland
Occipital presentation, posterior position
+∞
12.5
12
*
65202
ICD-8 Finland
Face presentation, posterior position
+∞
12.5
12
*
O62.2
ICD-10 Finland
Other uterine inertia
+∞
12.5
12
*
SPAT1192
SPAT
Gynaecological examination
1.5
12.5
487
3420
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
2.1
12.4
142
691
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
12.2
3183
29344
MBB10
NOMESCO Finland
Packing of delivered uterus
37.6
12.2
15
*
O03.4
ICD-10 Finland
Spontaneous abortion, Incomplete, without complication
2.3
12.1
115
516
O42.0
ICD-10 Finland
Premature rupture of membranes, onset of labour within 24 hours
2.7
12.1
80
297
O03.1
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage
2.7
12.0
80
299
8839
FHL
Other measure in this category
46.8
11.9
14
*
O42.1
ICD-10 Finland
Premature rupture of membranes, onset of labour after 24 hours
3.4
11.8
55
161
8803
FHL
Stern exit
14.7
11.8
19
13
SPAT1246
SPAT
Screening of depression or other psychiatric problem
1.9
11.5
177
966
WX400
NOMESCO Finland
Inhalation anesthesy
1.8
11.5
199
1132
6528B
ICD-9 Finland
Malposition and malpresentation of foetus, Other specified malposition or malpresentation[MUUT VIRHEASENNOT JA -TARJONNAT, SYNNYTYKSEN AIKANA]
+∞
11.5
11
*
65400
ICD-8 Finland
Occipital presentation
+∞
11.5
11
*
6631A
ICD-9 Finland
Umbilical cord complications, Cord around neck, with compression
+∞
11.5
11
*
W90
ICPC
Uncompl labour/delivery livebirth
1.9
11.2
171
933
V220A
ICD-9 Finland
Normal pregnancy, Supervision of normal first pregnancy
2.2
11.2
109
498
O36.8
ICD-10 Finland
Maternal care for other specified fetal problems
2.8
11.2
71
259
MAA00
NOMESCO Finland
Amniocentesis
2.3
11.1
103
459
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
2.5
11.0
86
353
G02CB01
ATC
bromocriptine; systemic
2.2
10.9
107
492
J01DA01
ATC
[U] cefalexin; systemic
1.2
10.8
2698
24558
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
1.8
10.8
191
1097
WW500
NOMESCO Finland
Blood transfusion
2.1
10.7
116
555
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
3.6
10.7
47
132
MBC33
NOMESCO Finland
Repair of complete rupture of perineum
28.1
10.7
14
5
67008
ICD-8 Finland
Sepsis of childbirth and the puerperium, Alia definita
2.8
10.7
67
242
8501
FHL
Emptying the uterus with suction
2.4
10.6
89
379
O36.4
ICD-10 Finland
Maternal care for intrauterine death
4.2
10.5
38
90
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.2
10.5
1507
12906
Z36.4
ICD-10 Finland
Antenatal screening for fetal growth retardation using ultrasound and other physical methods
2.7
10.4
70
263
O20.8
ICD-10 Finland
Other haemorrhage in early pregnancy
4.6
10.4
35
77
O65.4
ICD-10 Finland
Obstructed labour due to fetopelvic disproportion, unspecified
+∞
10.4
10
*
SPAT1391
SPAT
Counselling and guidance related to family situation
3.1
10.4
54
173
O32.2
ICD-10 Finland
Maternal care for transverse and oblique lie
4.3
10.3
37
87
O80.9
ICD-10 Finland
Single spontaneous delivery, unspecified
2.7
10.3
66
243
O30.0
ICD-10 Finland
Twin pregnancy
2.7
10.2
69
261
6370A
ICD-9 Finland
Unspecified abortion, Complicated by genital tract and pelvic infection
2.5
10.2
74
293
N81.1
ICD-10 Finland
Cystocele
1.5
10.1
299
1976
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
2.3
10.1
88
382
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.4
10.0
557
4177
SPAT1373
SPAT
Combined screening in early pregnancy
2.7
9.8
63
233
WX320
NOMESCO Finland
Spinalanesthesy
1.3
9.8
759
6000
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.2
9.7
1478
12709
W12
ICPC
Contraception intrauterine
1.4
9.6
424
3050
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.2
9.6
2086
18615
O73
ICD-10 Finland
Retained placenta and membranes, without haemorrhage
+∞
9.4
9
*
O68.9
ICD-10 Finland
Labour and delivery complicated by fetal stress, unspecified
+∞
9.4
9
*
6662A
ICD-9 Finland
Postpartum haemorrhage, Delayed and secondary postpartum haemorrhage
+∞
9.4
9
*
O75.7
ICD-10 Finland
Vaginal delivery following previous caesarean section
+∞
9.4
9
*
O67.8
ICD-10 Finland
Other intrapartum haemorrhage
+∞
9.4
9
*
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
1.6
9.3
233
1477
W27
ICPC
Fear of complications of pregnancy
3.4
9.2
42
123
J01DB01
ATC
cefalexin; oral
1.2
9.2
3567
33702
SPAT1187
SPAT
General ultrasound examination in early pregnancy
3.3
9.2
44
134
LGA10
NOMESCO Finland
Sterilisation by destruction or division of Fallopian tubes
3.2
9.2
46
145
6310A
ICD-9 Finland
Other abnormal product of conception[OVUM ABORTIVUM]
2.1
9.1
102
498
N39.3
ICD-10 Finland
Stress incontinence
1.5
9.1
345
2410
O26.82
ICD-10 Finland
Exhaustion and fatigue pregnancy-related
2.4
9.1
72
298
O90.8
ICD-10 Finland
Other complications of the puerperium, not elsewhere classified
9.0
9.0
18
20
J01CA08
ATC
pivmecillinam; oral
1.2
9.0
2170
19522
64598
ICD-8 Finland
Other abortion
2.6
8.9
62
242
O90.9
ICD-10 Finland
Complication of the puerperium, unspecified
7.9
8.8
19
24
ZXE00
NOMESCO Finland
One hour or less
1.2
8.8
1541
13417
WX230
NOMESCO Finland
Plexus blockade of nervus pudendus
3.1
8.7
45
145
O40
ICD-10 Finland
Polyhydramnios
3.0
8.6
48
163
MAB10
NOMESCO Finland
External version
3.6
8.6
37
104
MAB00
NOMESCO Finland
Cerclage of cervix of pregnant uterus
16.3
8.5
13
8
1412
FHL
Laparoscopy and sterilization
1.4
8.5
379
2732
O35.9
ICD-10 Finland
Maternal care for (suspected) fetal abnormality and damage, unspecified
2.9
8.4
49
171
65320
ICD-8 Finland
Occipital presentation
4.3
8.4
29
67
O26.6
ICD-10 Finland
Liver disorders in pregnancy, childbirth and the puerperium
2.4
8.3
68
290
PHD76
NOMESCO Finland
Resection of long saphenous vein
1.6
8.3
209
1333
63495
ICD-8 Finland
Other complications of pregnancy, Effluxus liquoris amnii praetemporarius
3.8
8.2
33
88
O14.0
ICD-10 Finland
Mild to moderate pre-eclampsia
2.3
8.1
73
326
N02BE01
ATC
paracetamol; systemic, rectal
1.2
8.1
3756
35828
WYA40
NOMESCO Finland
Assessment of oral health and treatment needs for family expecting first child
2.5
8.1
59
234
MBA10
NOMESCO Finland
Manual exploration of delivered uterus
33.4
8.1
10
*
B02AA02
ATC
tranexamic acid; systemic
1.3
8.1
813
6644
MAE03
NOMESCO Finland
Mid-cavity or high vacuum delivery
22.0
8.0
11
5
Z35.1
ICD-10 Finland
Supervision of pregnancy with history of abortive outcome
4.3
8.0
28
66
6581A
ICD-9 Finland
Other problems associated with amniotic cavity and membranes, Premature rupture of membranes
3.5
7.9
35
101
SAA02
NOMESCO Finland
Basic examination of mouth
1.2
7.9
2834
26308
SPAT1301
SPAT
No procedures
1.2
7.9
1094
9273
O91.2
ICD-10 Finland
Nonpurulent mastitis associated with childbirth
2.8
7.9
50
183
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.2
7.8
2246
20431
O28.8
ICD-10 Finland
Other abnormal findings on antenatal screening of mother
2.7
7.8
50
185
Z12.4
ICD-10 Finland
Special screening examination for neoplasm of cervix
1.8
7.8
130
736
LEF03
NOMESCO Finland
Posterior colporrpahy with sutures for primary rectocele
1.6
7.7
175
1086
8113
FHL
Fractional scraping
1.5
7.7
241
1619
OAA11
SPAT
NA
2.1
7.7
84
407
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.2
7.7
1641
14526
SPAT1308
SPAT
Sexual health counselling
1.3
7.6
487
3734
W18
ICPC
Post-partum symptom/complaint other
4.2
7.6
27
65
O44.0
ICD-10 Finland
Placenta praevia specified as without haemorrhage
3.0
7.5
40
133
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.2
7.5
2229
20308
O26.7
ICD-10 Finland
Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
2.8
7.4
44
157
V230A
ICD-9 Finland
Supervision of high-risk pregnancy, Pregnancy with history of infertility
2.5
7.4
56
230
SPAT1190
SPAT
Insertion or removal of intrauterine contraceptive device
1.5
7.4
259
1782
W03
ICPC
Antepartum bleeding
3.3
7.3
35
108
6591A
ICD-9 Finland
Other indications for care or intervention related to labour and delivery and not elsewhere classified, Failed medical or unspecified induction
+∞
7.3
7
*
O70.21
ICD-10 Finland
III degree perineal tear involving less than one half of external anal sphincter thickness torn during childbirth
+∞
7.3
7
*
6620B
ICD-9 Finland
Long labour, Prolonged first stage
+∞
7.3
7
*
65219
ICD-8 Finland
UNS
+∞
7.3
7
*
6640B
ICD-9 Finland
Trauma to perineum and vulva during delivery, First-degree perineal laceration
+∞
7.3
7
*
O71.7
ICD-10 Finland
Obstetric haematoma of pelvis
+∞
7.3
7
*
66130
ICD-8 Finland
Occipital presentation
+∞
7.3
7
*
6641B
ICD-9 Finland
Trauma to perineum and vulva during delivery, Second-degree perineal laceration
+∞
7.3
7
*
SPAT1315
SPAT
Periodic health check-up of children and adolescents
1.9
7.3
105
569
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
2.4
7.3
59
252
TQW30
NOMESCO Finland
Acupuncture
4.0
7.1
26
65
SPAT1312
SPAT
General health counselling
1.2
7.0
1192
10298
XLA10
NOMESCO Finland
NA
1.5
7.0
269
1884
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
3.3
6.9
32
97
N81.2
ICD-10 Finland
Incomplete uterovaginal prolapse
1.5
6.9
221
1493
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.2
6.9
1012
8617
Z30.1
ICD-10 Finland
Insertion of (intrauterine) contraceptive device
1.3
6.9
505
3956
6320A
ICD-9 Finland
Missed abortion[ABORTUS INHIBITUS (""""MISSED ABORTION"""")]
2.2
6.7
65
299
PC7NT
NOMESCO Finland
Endovascular occlusion of uteral arteries to stop puerperal bleeding
22.5
6.7
9
*
MAB20
NOMESCO Finland
Failed external version
2.6
6.7
47
185
SAA03
NOMESCO Finland
Extended examination of mouth
1.2
6.7
1579
14061
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.2
6.7
997
8502
LCA16
NOMESCO Finland
Destruction of endometrium
2.0
6.6
74
364
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.2
6.6
2490
23040
O86.0
ICD-10 Finland
Infection of obstetric surgical wound
3.4
6.6
29
85
MBA40
NOMESCO Finland
Pharmacological evacuation of uterus after abortion
2.3
6.5
56
247
6748X
ICD-9 Finland
Other and unspecified complications of the puerperium, not elsewhere classified, Other
4.5
6.4
21
47
67791
ICD-8 Finland
Other and unspecified complications of the puerperium, Haemorrhagia tarde (alia)
7.4
6.4
14
19
O28.3
ICD-10 Finland
Abnormal ultrasonic finding on antenatal screening of mother
3.0
6.4
33
109
LGA20
NOMESCO Finland
Sterilisation by constriction of Fallopian tubes
2.4
6.4
49
204
SPAT1310
SPAT
Counselling related to known health issue
1.2
6.3
1154
10027
O71.1
ICD-10 Finland
Rupture of uterus during labour
+∞
6.2
6
*
O43.2
ICD-10 Finland
Morbidly adherent placenta
+∞
6.2
6
*
O61.1
ICD-10 Finland
Failed instrumental induction of labour
+∞
6.2
6
*
MBB96
NOMESCO Finland
Other manual procedure on delivered uterus
+∞
6.2
6
*
MBC96
NOMESCO Finland
Other repair of obstetric laceration
+∞
6.2
6
*
6690A
ICD-9 Finland
Other complications of labour and delivery, not elsewhere classified, Maternal distress
+∞
6.2
6
*
6661X
ICD-9 Finland
Postpartum haemorrhage, Other immediate postpartum haemorrhage[HAEMORRHAGIA POST PARTUM ACUTA ALIA]
+∞
6.2
6
*
MCA30
NOMESCO Finland
Supravaginal caesarean hysterectomy
+∞
6.2
6
*
65216
ICD-8 Finland
Complete or incomplete breech presentation
+∞
6.2
6
*
63494
ICD-8 Finland
Other complications of pregnancy, Insufficientia cervicis
3.1
6.2
31
100
I83.9
ICD-10 Finland
Varicose veins of lower extremities without ulcer or inflammation
1.3
6.2
413
3188
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.2
6.2
2354
21746
O99.5
ICD-10 Finland
Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium
2.6
6.2
41
157
Z09.8
ICD-10 Finland
Follow-up examination after other treatment for other conditions
1.6
6.2
141
878
SGA01
NOMESCO Finland
Tooth opening as first aid
1.3
6.2
603
4898
O20
ICD-10 Finland
Haemorrhage in early pregnancy
5.0
6.2
18
36
O84.0
ICD-10 Finland
Multiple delivery, all spontaneous
3.1
6.2
31
101
Z35
ICD-10 Finland
Supervision of high-risk pregnancy
2.9
6.2
34
118
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.2
6.1
1018
8762
64594
ICD-8 Finland
Other abortion, Retentio ovi (partialis)
1.9
6.1
81
428
WX322
NOMESCO Finland
Combined spinal-epidural analgesia in obstetrics
2.2
6.1
54
243
K02.1
ICD-10 Finland
Caries of dentine
1.2
6.1
2383
22058
O86.3
ICD-10 Finland
Other genitourinary tract infections following delivery
8.6
6.0
12
14
LCA96
NOMESCO Finland
Other intrauterine operation
2.5
6.0
43
171
W82
ICPC
Abortion spontaneous
3.0
6.0
31
103

Mortality – FinRegistry

Association

Association between endpoint O15_RETAINED_PLAC_MEMB_NO_HEAMORRH and mortality.

Females

Parameter HR [95% CI] p-value
O15_RETAINED_PLAC_MEMB_NO_HEAMORRH 0.591 [0.46, 0.76] < 0.001
Birth year 0.992 [0.98, 1.0] 0.069

During the follow-up period (1.1.1998 — 31.12.2019), 69 out of 12731 females with O15_RETAINED_PLAC_MEMB_NO_HEAMORRH died.

Males

No data

Mortality risk

Mortality risk for people of age

years, who have O15_RETAINED_PLAC_MEMB_NO_HEAMORRH.

N-year risk Females Males
1 0.049% No data
5 0.299% No data
10 0.805% No data
15 1.466% No data
20 2.67% No data

Relationships between endpoints

Index endpoint: O15_RETAINED_PLAC_MEMB_NO_HEAMORRH – Retained placenta and membranes, without haemorrhage

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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