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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Traumatic cerebral oedema

ST19_TRAUMAT_CEREBRAL_OEDEMA

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 S06.1
  • Cause of death: ICD-10 S06.1

2 out of 7 registries used, show all original rules.

120

4. Check minimum number of events

None

120

5. Include endpoints

None

120

6. Filter based on genotype QC (FinnGen only)

120

Control definitions (FinnGen only)

Control exclude
NEURODIS

Extra metadata

Level in the ICD hierarchy
4
Special
ST19_TRAUMCOEDMA
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
S06
Name in latin
Oedema cerebri/encephali traumaticum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 120 46 74
Unadjusted period prevalence (%) 0.03 0.02 0.03
Median age at first event (years) 49.31 46.28 51.20

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
108
Matched controls
1080
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
S06.1
ICD-10 Finland
Traumatic cerebral oedema
+∞
155.8
108
*
S06.0
ICD-10 Finland
Concussion
52.2
32.4
38
11
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
+∞
29.5
27
*
AA1AD
NOMESCO Finland
CT of head and brain
15.2
26.3
47
52
T90.5
ICD-10 Finland
Sequelae of intracranial injury
160.7
24.8
25
*
S06.2
ICD-10 Finland
Diffuse brain injury
+∞
22.7
21
*
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
+∞
16.0
15
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
6.0
14.7
49
132
S06.3
ICD-10 Finland
Focal brain injury
+∞
13.8
13
*
W19
ICD-10 Finland
Unspecified fall
9.8
12.2
25
32
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
+∞
10.6
10
*
R51.80
ICD-10 Finland
Headache
7.2
10.2
25
43
S42.0
ICD-10 Finland
Fracture of clavicle
24.3
9.6
13
6
N03AX14
ATC
levetiracetam; systemic
+∞
9.5
9
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
5.7
9.4
28
62
N03AF02
ATC
oxcarbazepine; oral
40.4
9.2
11
*
G47.3
ICD-10 Finland
Sleep apnoea
14.4
8.7
14
11
G40.9
ICD-10 Finland
Epilepsy, unspecified
+∞
8.4
8
*
AAF00
NOMESCO Finland
Ventriculostomy
+∞
8.4
8
*
JN5BD
NOMESCO Finland
Head and body CT examination for trauma
36.4
8.2
10
*
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
48.6
7.8
9
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
11.3
7.8
14
14
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
5.6
7.6
22
47
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
85.7
7.5
8
*
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
7.5
7.5
17
26
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
+∞
7.4
7
*
AAA27
NOMESCO Finland
Insertion of intracerebral pressure monitoring device
+∞
7.4
7
*
S02.11
ICD-10 Finland
Fracture of base of skull, open
+∞
7.4
7
*
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
+∞
7.4
7
*
X59
ICD-10 Finland
Exposure to unspecified factor
4.0
7.3
31
98
G44.2
ICD-10 Finland
Tension-type headache
8.0
7.3
16
23
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
9.9
7.3
14
16
V49.9
ICD-10 Finland
Car occupant [any] injured in unspecified traffic accident
9.9
7.3
14
16
XA800
NOMESCO Finland
Neuropsychological investigation
32.4
7.3
9
*
N03AX12
ATC
gabapentin; oral
6.2
7.2
19
36
R56.8
ICD-10 Finland
Other and unspecified convulsions
10.4
7.0
13
14
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
11.1
6.7
12
12
N80
ICPC
Head injury other
74.0
6.5
7
*
S02.10
ICD-10 Finland
Fracture of base of skull, closed
74.0
6.5
7
*
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
74.0
6.5
7
*
ZXD05
NOMESCO Finland
Urgent procedure
3.1
6.5
41
176
N06AB04
ATC
citalopram; systemic
3.8
6.5
29
96
Z2445
NOMESCO Finland
Psychologist
12.1
6.5
11
10
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
+∞
6.3
6
*
S06.6
ICD-10 Finland
Traumatic subarachnoid haemorrhage
+∞
6.3
6
*
AAD10
NOMESCO Finland
Evacuation of chronic subdural haematoma
+∞
6.3
6
*
S06.4
ICD-10 Finland
Epidural haemorrhage
+∞
6.3
6
*
W17
ICD-10 Finland
Other fall from one level to another
11.0
6.2
11
11
N05BA04
ATC
oxazepam; oral
3.6
6.1
29
100

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: ST19_TRAUMAT_CEREBRAL_OEDEMA – Traumatic cerebral oedema

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).