pars planitis: Form of granulomatous uveitis occurring in the region of the pars plana. This disorder is a common condition with no detectable focal pathology. It causes fibrovascular proliferation at the inferior ora serrata.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1051 |
4. Check minimum number of eventsNone |
1051 |
5. Include endpointsNone |
1051 |
6. Filter based on genotype QC (FinnGen only) |
1051 |
Control definitions (FinnGen only)
- Control exclude
- H7_CHOROIDRETINA
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF6
Similar endpoints
↥List of similar endpoints to
Chorioretinal inflammation
based on the number of shared cases.
Similar with more cases:
- Disorders of choroid and retina
- Diseases of the eye and adnexa
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 7447 | 4043 | 3349 |
| Only index persons | 6715 | 3705 | 3010 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.11 | 0.12 | 0.09 |
| Only index persons | 0.13 | 0.14 | 0.11 |
| Median age at first event (years) | |||
| Whole population | 44.36 | 45.40 | 43.18 |
| Only index persons | 43.01 | 43.90 | 41.91 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1051 | 620 | 431 |
| Unadjusted period prevalence (%) | 0.20 | 0.21 | 0.19 |
| Median age at first event (years) | 45.67 | 42.74 | 49.88 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 957
- Matched controls
- 9571
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
H30.2
ICD-10 Finland
Posterior cyclitis
+∞
323.0
356
*
H30.9
ICD-10 Finland
Chorioretinal inflammation, unspecified
+∞
221.7
204
*
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
28.4
192.1
268
129
H20.1
ICD-10 Finland
Chronic iridocyclitis
126.9
183.1
193
19
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
386.0
134.2
132
*
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
15.2
124.7
217
181
H30.0
ICD-10 Finland
Focal chorioretinal inflammation
+∞
119.3
112
*
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
16.5
108.1
180
132
XCK10
NOMESCO Finland
Photography of fundus of eye
9.2
105.2
240
336
XCW99
NOMESCO Finland
Other investigative procedure of eye
9.0
102.5
237
338
CKC12
NOMESCO Finland
Photocoagulation of retina
187.8
98.3
101
6
Z01.0
ICD-10 Finland
Examination of eyes and vision
5.9
93.2
306
709
Z96.1
ICD-10 Finland
Presence of intraocular lens
7.8
93.2
236
384
H30.1
ICD-10 Finland
Disseminated chorioretinal inflammation
+∞
90.0
85
*
S01ED51
ATC
timolol, combinations; ophthalmic
9.9
82.7
177
215
H35.39
ICD-10 Finland
Degeneration of macula and posterior pole
408.7
76.9
76
*
H02AB06
ATC
prednisolone; systemic
3.5
72.5
596
3077
WX140
NOMESCO Finland
Parabulbar anesthesy
21.4
71.5
107
56
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
3.9
66.3
340
1180
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
148.4
65.8
69
5
H40.5
ICD-10 Finland
Glaucoma secondary to other eye disorders
104.4
62.7
68
7
H30.8
ICD-10 Finland
Other chorioretinal inflammations
+∞
62.2
59
*
H32.0*B58.0
ICD-10 Finland
Toxoplasma chorioretinitis
+∞
62.2
59
*
H33.0
ICD-10 Finland
Retinal detachment with retinal break
333.8
62.1
62
*
XCD20
NOMESCO Finland
Photoangiography of eye
213.0
58.7
60
*
36504
ICD-8 Finland
Choroiditis, Retinis, Retino-chorioiditis
+∞
56.8
54
*
H35.31
ICD-10 Finland
Senile macular degeneration (atrophic)(exudative)
580.4
56.2
55
*
S01ED01
ATC
timolol; ophthalmic
13.4
53.7
96
79
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
25.8
52.8
74
31
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
4.9
52.5
189
454
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
3.0
51.6
402
1842
H26.2
ICD-10 Finland
Complicated cataract
47.2
51.1
62
14
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
4.5
49.6
199
532
H35.38
ICD-10 Finland
Preretinal fibrosis of the macula
51.3
48.5
58
12
CKD40
NOMESCO Finland
Endophotocoagulation of retina
+∞
48.3
46
*
S01EC01
ATC
acetazolamide; systemic
17.1
47.3
76
48
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
31.5
46.8
62
21
H3603, E103
ICD-10 Finland
NA
+∞
46.2
44
*
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
+∞
46.2
44
*
S01BA04
ATC
prednisolone; ophthalmic (corticosteroids, plain)
12.9
45.9
83
70
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.7
44.9
455
2400
CJB10
NOMESCO Finland
Laser discission of secondary cataract
6.6
44.7
122
208
H33.3
ICD-10 Finland
Retinal breaks without detachment
235.7
44.3
45
*
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
13.0
43.3
78
65
XCK00
NOMESCO Finland
Perimetry
6.1
42.7
123
225
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.6
42.6
476
2630
H3600, E103
ICD-10 Finland
NA
+∞
39.9
38
*
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
7.5
39.1
96
140
H43.1
ICD-10 Finland
Vitreous haemorrhage
30.4
39.0
52
18
H3601, E103
ICD-10 Finland
NA
+∞
38.8
37
*
S01EA05
ATC
brimonidine; ophthalmic (sympathomimetics in glaucoma therapy)
14.7
38.4
65
47
D86.8
ICD-10 Finland
Sarcoidosis of other and combined sites
23.3
38.3
55
25
A10AA01
ATC
NA
15.2
38.2
64
45
CK9F4
NOMESCO Finland
Fluorescein angiography (FAG) of choroid and retina
197.5
37.0
38
*
H32.0
ICD-10 Finland
Chorioretinal inflammation in infectious and parasitic diseases classified elsewhere
+∞
36.7
35
*
CKC10
NOMESCO Finland
Local photocoagulation of retina
+∞
36.7
35
*
CK2L4
NOMESCO Finland
Wide-field/panoramic imaging of ocular fundus
37.1
36.2
46
13
H35.30
ICD-10 Finland
Kuhnt-Junius degeneration
44.9
35.2
43
10
H26.4
ICD-10 Finland
After-cataract
5.3
35.2
114
239
114
Kela drug reimbursment
Glaucoma
4.9
35.0
123
282
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
7.8
35.0
83
115
WX100
NOMESCO Finland
Conjunctival surface anesthesia
4.2
34.3
143
388
CKA10
NOMESCO Finland
Biopsy of vitreous body
348.9
34.1
34
*
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
348.9
34.1
34
*
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
9.8
33.6
69
75
A10AA02
ATC
NA
11.2
32.8
63
60
CKD10
NOMESCO Finland
Insufflation of vitreous cavity
322.8
31.0
31
*
S01BC03
ATC
diclofenac; ophthalmic
9.4
30.6
64
72
CKC15
NOMESCO Finland
Panretinal photocoagulation
+∞
30.4
29
*
S01CA02
ATC
prednisolone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
15.4
30.3
50
34
XCH00
NOMESCO Finland
Eye pressure measurement
7.8
29.7
70
96
CKD91
NOMESCO Finland
Extended vitrectomy through pars plana
300.5
28.9
29
*
H04AA01
ATC
glucagon; nasal, parenteral
12.4
28.7
52
44
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
4.8
28.5
99
223
36509
ICD-8 Finland
Choroiditis, Unspecified
+∞
28.3
27
*
3632A
ICD-9 Finland
Chorioretinal inflammations and scars and other disorders of choroid, Other and unspecified forms of chorioretinitis and retinochoroiditis
+∞
28.3
27
*
H02AB07
ATC
prednisone; oral
2.9
27.8
189
743
A10AE05
ATC
insulin detemir; parenteral
5.8
27.2
80
149
H35.9
ICD-10 Finland
Retinal disorder, unspecified
+∞
26.2
25
*
H22.1*D86.8
ICD-10 Finland
Iridocyclitis in sarcoidosis
+∞
26.2
25
*
H34.8
ICD-10 Finland
Other retinal vascular occlusions
+∞
26.2
25
*
D86.0
ICD-10 Finland
Sarcoidosis of lung
11.7
25.9
48
43
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
267.4
25.8
26
*
Z3229
NOMESCO Finland
Other healthcare associate professional
3.8
25.8
116
334
CHD50
NOMESCO Finland
Shunt operation on anterior chamber
138.7
25.7
27
*
H20.9
ICD-10 Finland
Iridocyclitis, unspecified
13.1
25.5
45
36
H26.3
ICD-10 Finland
Drug-induced cataract
24.2
24.9
35
15
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
12.7
24.7
44
36
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
4.2
24.5
97
249
36501
ICD-8 Finland
Choroiditis, Centralis
+∞
24.1
23
*
S01FA04
ATC
cyclopentolate; ophthalmic
16.4
23.8
38
24
H43.8
ICD-10 Finland
Other disorders of vitreous body
3.6
23.8
115
351
H35.36
ICD-10 Finland
Macular cyst
245.8
23.7
24
*
S01BA07
ATC
fluorometholone; ophthalmic (corticosteroids, plain)
9.7
23.5
48
52
T89
ICPC
Diabetes insulin dependent
6.8
23.0
59
92
H40.4
ICD-10 Finland
Glaucoma secondary to eye inflammation
66.7
22.9
26
*
A02BC02
ATC
pantoprazole; systemic
2.0
22.7
628
4669
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
10.4
22.5
44
44
A10AD01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
15.5
22.1
36
24
H35.7
ICD-10 Finland
Separation of retinal layers
+∞
22.0
21
*
H35.0
ICD-10 Finland
Background retinopathy and retinal vascular changes
+∞
22.0
21
*
H25.1
ICD-10 Finland
Senile nuclear cataract
2.4
21.9
213
1015
CKD94
NOMESCO Finland
Combined vitrectomy and procedure on lens through pars plana
82.0
21.8
24
*
H35.8
ICD-10 Finland
Other specified retinal disorders
117.7
21.7
23
*
S01BC05
ATC
ketorolac; ophthalmic
6.4
21.0
56
92
36508
ICD-8 Finland
Choroiditis, Alia definita
+∞
20.9
20
*
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
+∞
20.9
20
*
E10
ICD-10 Finland
Type 1 diabetes mellitus
11.2
20.8
39
36
H25.8
ICD-10 Finland
Other senile cataract
3.4
20.7
107
344
H40.0
ICD-10 Finland
Glaucoma suspect
3.7
20.6
95
279
S01EA03
ATC
apraclonidine; ophthalmic
20.6
20.5
30
15
S01EC04
ATC
brinzolamide; ophthalmic
6.4
20.4
54
88
CK9G4
NOMESCO Finland
Iridocyanine green angiography (ICGA) of choroid and retina
+∞
19.9
19
*
CKD20
NOMESCO Finland
Removal of vitreous body substitute
+∞
19.9
19
*
H3601, E113
ICD-10 Finland
NA
+∞
19.9
19
*
ZXA10
NOMESCO Finland
Bilateral
2.4
19.0
186
884
A10AE04
ATC
insulin glargine; parenteral
3.2
18.8
102
340
H36.01
ICD-10 Finland
Diabetic maculopathy
193.5
18.6
19
*
CKD92
NOMESCO Finland
Combined vitrectomy and retinal procedure
193.5
18.6
19
*
XCD10
NOMESCO Finland
Electrophysiological examination of eye
7.8
18.3
42
56
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
22.2
18.2
26
12
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
5.7
18.0
52
95
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
53.6
18.0
21
*
CKD15
NOMESCO Finland
Injection of vitreous substitute
+∞
17.8
17
*
36503
ICD-8 Finland
Choroiditis, Juxta-papillaris
+∞
17.8
17
*
H3603, E113
ICD-10 Finland
NA
+∞
17.8
17
*
QXA20
NOMESCO Finland
Skin abrasion, unspecified location
37.5
17.7
22
6
CS494
NOMESCO Finland
Other visual field testing
7.6
17.6
41
56
S01EC54
ATC
brinzolamide, combinations; ophthalmic
15.1
17.2
28
19
H35.5
ICD-10 Finland
Hereditary retinal dystrophy
+∞
16.7
16
*
TCF00
NOMESCO Finland
Subconjunctival therapeutic injection
172.8
16.5
17
*
S01EE01
ATC
latanoprost; ophthalmic
4.0
16.4
67
177
A07EC01
ATC
sulfasalazine; oral, rectal
3.0
16.3
97
342
A10AA03
ATC
NA
21.4
16.0
23
11
D86.9
ICD-10 Finland
Sarcoidosis, unspecified
10.6
15.8
30
29
TAB00
NOMESCO Finland
Lumbar puncture
3.8
15.7
68
190
CKW99
NOMESCO Finland
Other operation on choroid, vitreous body and retina
+∞
15.7
15
*
H20.8
ICD-10 Finland
Other iridocyclitis
26.8
15.6
21
8
A10AE06
ATC
insulin degludec; parenteral
5.9
15.4
43
76
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.9
15.4
310
1962
H25.0
ICD-10 Finland
Senile incipient cataract
3.8
15.3
65
178
D86.2
ICD-10 Finland
Sarcoidosis of lung with sarcoidosis of lymph nodes
9.9
15.3
30
31
H54.2
ICD-10 Finland
Moderate visual impairment, binocular
29.1
15.2
20
7
M45
ICD-10 Finland
Ankylosing spondylitis
6.8
15.2
38
58
B58.0
ICD-10 Finland
Toxoplasma oculopathy
+∞
14.6
14
*
132
Kela drug reimbursment
Sarcoidosis
15.7
14.4
23
15
CA1CG
NOMESCO Finland
Eye and orbita extensive MRI examination with high intensity magnet
13.6
14.3
24
18
S01EE05
ATC
tafluprost; ophthalmic
5.2
14.0
43
86
CK2A4
NOMESCO Finland
Autofluorescence imaging of ocular fundus
24.2
13.8
19
8
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
24.2
13.8
19
8
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.8
13.8
89
333
SPAT1262
SPAT
Handing over of treatment supplies
2.1
13.8
177
943
H46
ICD-10 Finland
Optic neuritis
10.2
13.5
26
26
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
16.5
13.5
21
13
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
16.5
13.5
21
13
R4180
NOMESCO Finland
Podiatric therapy
13.1
13.4
23
18
L04AX01
ATC
azathioprine; systemic
3.5
13.3
63
190
S01FA02
ATC
scopolamine; ophthalmic
10.7
13.3
25
24
J01FF01
ATC
clindamycin; systemic
1.8
13.2
260
1619
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
17.0
13.0
20
12
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.8
12.8
82
305
S01EE03
ATC
bimatoprost; ophthalmic
6.3
12.7
33
54
CKD93
NOMESCO Finland
Extended combined procedure on vitreous body and retina
+∞
12.5
12
*
H28.0*E10.3
ICD-10 Finland
Other specified diabetes mellitus - Diabetic cataract
+∞
12.5
12
*
3630A
ICD-9 Finland
Chorioretinal inflammations and scars and other disorders of choroid, Focal chorioretinitis and focal retinochoroiditis
+∞
12.5
12
*
H04.10
ICD-10 Finland
Dry eye syndrome
2.5
12.5
103
442
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
5.0
12.4
39
80
L04AB04
ATC
adalimumab; parenteral
5.6
12.3
35
64
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.9
12.3
211
1249
Z3231
NOMESCO Finland
Registered nurse
1.8
12.2
254
1604
103
Kela drug reimbursment
Diabetes, insulin-treated
1.8
12.2
225
1367
D86.1
ICD-10 Finland
Sarcoidosis of lymph nodes
11.9
11.9
21
18
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
3.6
11.5
51
146
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
6.8
11.5
28
42
H3602, E103
ICD-10 Finland
NA
+∞
11.5
11
*
H35.37
ICD-10 Finland
Macular holes
+∞
11.5
11
*
36500
ICD-8 Finland
Choroiditis, Anterior
+∞
11.5
11
*
H35.4
ICD-10 Finland
Peripheral retinal degeneration
121.4
11.4
12
*
157
Kela drug reimbursment
Dimethyl fumarate, glatiramer acetate, interferon beta and teriflunomid (Multiple sclerosis)
11.3
11.1
20
18
ZXA05
NOMESCO Finland
Left side
1.8
11.1
223
1387
WX002
NOMESCO Finland
Sedation and analgesia
1.9
10.7
177
1027
H53.9
ICD-10 Finland
Visual disturbance, unspecified
4.2
10.6
39
95
TCW99
NOMESCO Finland
Other minor procedure in eye surgery
8.6
10.6
22
26
H44.1
ICD-10 Finland
Other endophthalmitis
111.1
10.4
11
*
1302A
ICD-9 Finland
Toxoplasmosis, Chorioretinitis due to toxoplasmosis
+∞
10.4
10
*
3641A
ICD-9 Finland
Disorders of iris and ciliary body, Chronic iridocyclitis
+∞
10.4
10
*
H26.02
ICD-10 Finland
Presenil cataract
4.5
10.4
36
83
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.6
10.4
77
315
109
Kela drug reimbursment
Multiple sclerosis
8.3
10.3
22
27
L04AA06
ATC
mycophenolic acid; systemic
5.4
10.0
29
55
CHC05
NOMESCO Finland
Iridotomy
7.3
10.0
23
32
H20
ICD-10 Finland
Iridocyclitis
20.3
9.8
14
7
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.7
9.8
251
1674
H53.1
ICD-10 Finland
Subjective visual disturbances
2.7
9.7
66
257
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
3.9
9.7
39
104
H22.1
ICD-10 Finland
Iridocyclitis in other diseases classified elsewhere
55.5
9.7
11
*
ZXA00
NOMESCO Finland
Right side
1.7
9.6
231
1508
ZXE00
NOMESCO Finland
One hour or less
1.6
9.5
354
2601
H36.09*E11.3
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic retinopathy
101.0
9.4
10
*
B23.8
ICD-10 Finland
HIV disease resulting in other specified conditions
101.0
9.4
10
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.9
9.4
56
201
36502
ICD-8 Finland
Choroiditis, Disseminata
+∞
9.4
9
*
CK2Y4
NOMESCO Finland
OCT video recording of ocular fundus
+∞
9.4
9
*
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
2.2
9.2
91
431
SPAT1263
SPAT
Sampling
1.5
9.0
372
2785
TCG40
NOMESCO Finland
Measurement of higher-grade errors of refraction
18.8
8.9
13
7
S01FA01
ATC
atropine; ophthalmic
24.2
8.9
12
5
CHB10
NOMESCO Finland
Puncture of anterior chamber of eye with irrigation
24.2
8.9
12
5
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
3.9
8.9
35
92
H47.1
ICD-10 Finland
Papilloedema, unspecified
12.7
8.9
15
12
G35
ICD-10 Finland
Multiple sclerosis
5.0
8.9
27
55
H21.1
ICD-10 Finland
Other vascular disorders of iris and ciliary body
50.4
8.7
10
*
S01EE04
ATC
travoprost; ophthalmic
5.9
8.6
23
40
H33.5
ICD-10 Finland
Other retinal detachments
27.8
8.5
11
*
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
6.8
8.4
20
30
H3600, E113
ICD-10 Finland
NA
+∞
8.3
8
*
CKC60
NOMESCO Finland
Local buckling of sclera using implant
+∞
8.3
8
*
36700
ICD-8 Finland
Inflammation of optic nerve and retina, Retinitis infectiosa
+∞
8.3
8
*
CKC30
NOMESCO Finland
Cryopexy of detached retina
+∞
8.3
8
*
H34.2
ICD-10 Finland
Other retinal artery occlusions
+∞
8.3
8
*
H32.0*A18.5
ICD-10 Finland
Lupus chorioretinitis
+∞
8.3
8
*
H16.0
ICD-10 Finland
Corneal ulcer
2.7
8.3
53
200
H10.3
ICD-10 Finland
Acute conjunctivitis, unspecified
2.6
8.3
60
243
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
4.0
8.2
31
79
H43.3
ICD-10 Finland
Other vitreous opacities
6.1
8.2
21
35
J01MA12
ATC
levofloxacin; systemic
1.8
8.1
159
972
171
Kela drug reimbursment
Degludekinsuliini
33.6
8.1
10
*
CA1BG
NOMESCO Finland
Eye and orbita MRI examination with high intensity magnet
17.3
8.1
12
7
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
17.3
8.1
12
7
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
10.1
8.0
15
15
H57.1
ICD-10 Finland
Ocular pain
3.3
8.0
38
117
SPAT1299
SPAT
Other function in accordance with podiatry nomenclature
5.6
8.0
22
40
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.9
8.0
119
667
F29
ICPC
Eye symptom/complaint other
2.3
7.9
72
328
ZX198
NOMESCO Finland
Other local administration
13.2
7.9
13
10
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.2
7.9
79
375
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
7.8
403
3145
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
7.7
306
2250
ZX120
NOMESCO Finland
Intravenous
2.1
7.7
87
434
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.5
7.6
415
3272
G37.9
ICD-10 Finland
Demyelinating disease of central nervous system, unspecified
8.1
7.6
16
20
D86.3
ICD-10 Finland
Sarcoidosis of skin
18.5
7.6
11
6
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
12.0
7.6
13
11
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.6
7.5
238
1661
H11.3
ICD-10 Finland
Conjunctival haemorrhage
3.1
7.5
39
130
CM2S4
NOMESCO Finland
Follow-up photography of age-related macular degeneration lesions
80.7
7.4
8
*
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
2.9
7.3
42
147
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
6.9
7.3
17
25
TCH12
NOMESCO Finland
Sample aspiration from anterior chambre
+∞
7.3
7
*
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
6.3
7.3
18
29
B37.7
ICD-10 Finland
Candidal sepsis
15.9
7.2
11
7
B24
ICD-10 Finland
Unspecified human immunodeficiency virus [HIV] disease
15.9
7.2
11
7
303
Kela drug reimbursment
Dimethyl fumarate, interferon beta, glatiramer acetate and teriflunomid (Multiple sclerosis)
8.0
7.1
15
19
H53.4
ICD-10 Finland
Visual field defects
4.0
7.0
26
66
H40.13
ICD-10 Finland
Chronic glaucoma with open ventricular angle
2.9
7.0
40
141
N02BE01
ATC
paracetamol; systemic, rectal
1.5
7.0
770
6951
WX142
NOMESCO Finland
Sub-tenon anesthesy
13.9
6.9
11
8
WVC10
NOMESCO Finland
Subcutaneous infusion of drugs
13.9
6.9
11
8
B23.1
ICD-10 Finland
HIV disease resulting in (persistent) generalized lymphadenopathy
13.9
6.9
11
8
J05AB11
ATC
valaciclovir; oral
1.8
6.9
117
685
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.6
6.9
169
1105
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
2.8
6.9
42
156
P01BA02
ATC
hydroxychloroquine; oral
2.1
6.8
77
388
H26.8
ICD-10 Finland
Other specified cataract
11.0
6.8
12
11
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
2.3
6.8
62
284
36402
ICD-8 Finland
Iritis, Iridocyclitis, uveitis chronica
40.3
6.8
8
*
R59.0
ICD-10 Finland
Localized enlarged lymph nodes
2.9
6.7
38
133
TGC00
NOMESCO Finland
Bronchial lavation
3.5
6.6
29
85
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
6.6
139
865
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.2
6.6
66
315
H16.2
ICD-10 Finland
Keratoconjunctivitis
8.8
6.6
13
15
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.6
6.6
170
1123
CS1H4
NOMESCO Finland
Retinal nerve fibre layer imaging
6.9
6.5
15
22
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.0
6.5
82
431
H33.1
ICD-10 Finland
Retinoschisis and retinal cysts
70.3
6.4
7
*
H31.0
ICD-10 Finland
Chorioretinal scars
70.3
6.4
7
*
2504B
ICD-9 Finland
Diabetes mellitus, Diabetes with renal manifestations[DIABETES MELLITUS CUM COMPLICATIONE OCULI ,TYYPPI I]
70.3
6.4
7
*
H40.6
ICD-10 Finland
Glaucoma secondary to drugs
70.3
6.4
7
*
H36.00
ICD-10 Finland
Diabetic background retinopathy
70.3
6.4
7
*
L03AB07
ATC
interferon beta-1a; parenteral
11.1
6.3
11
10
CJF30
NOMESCO Finland
Reduction of dislocation of artificial lens
+∞
6.3
6
*
CM2X4
NOMESCO Finland
Follow-up OCT of age-related macular degeneration lesions
+∞
6.3
6
*
3610A
ICD-9 Finland
Retinal detachments and defects, Retinal detachment with retinal defect
+∞
6.3
6
*
CKD95
NOMESCO Finland
Extended combined vitectomy and lens procedure through pars plana
+∞
6.3
6
*
H54.1
ICD-10 Finland
Severe visual impairment, binocular
+∞
6.3
6
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.9
6.2
94
528
H40.9
ICD-10 Finland
Glaucoma, unspecified
4.8
6.2
19
40
3663A
ICD-9 Finland
Cataract secondary to ocular disorders
26.8
6.2
8
*
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
4.1
6.2
22
54
N03AX12
ATC
gabapentin; oral
1.7
6.2
129
804
S01ED02
ATC
betaxolol; ophthalmic
6.3
6.2
15
24
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.5
6.1
210
1483
WX204
NOMESCO Finland
Axillary plexus blockaced
3.0
6.1
33
114
N30.0
ICD-10 Finland
Acute cystitis
1.8
6.1
110
658
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
6.0
227
1638
Mortality – FinRegistry
↥Association
Association between endpoint H7_CHORIORETINFLAM and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CHORIORETINFLAM | 1.329 [1.13, 1.57] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.086 |
During the follow-up period (1.1.1998 — 31.12.2019), 402 out of 2634 females with H7_CHORIORETINFLAM died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| H7_CHORIORETINFLAM | 1.492 [1.26, 1.77] | < 0.001 |
| Birth year | 0.984 [0.97, 0.99] | 0.001 |
During the follow-up period (1.1.1998 — 31.12.2019), 397 out of 2150 males with H7_CHORIORETINFLAM died.
Mortality risk
Mortality risk for people of age
years, who have H7_CHORIORETINFLAM.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.139% | 0.289% |
| 5 | 0.664% | 1.79% |
| 10 | 1.88% | 4.127% |
| 15 | 3.62% | 7.326% |
| 20 | 6.451% | 12.661% |
Relationships between endpoints
↥Index endpoint: H7_CHORIORETINFLAM – Chorioretinal inflammation
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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