arthritis: An inflammatory process affecting a joint. Causes include infection, autoimmune processes, degenerative processes, and trauma. Signs and symptoms may include swelling around the affected joint and pain.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
1436 |
4. Check minimum number of eventsNone |
1436 |
5. Include endpointsNone |
1436 |
6. Filter based on genotype QC (FinnGen only) |
1436 |
Control definitions (FinnGen only)
- Control exclude
- M13_ARTHROPATHIES
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M13
- Name in latin
- Polyarthritis NAS
Similar endpoints
↥List of similar endpoints to
Polyarthritis, unspecified
based on the number of shared cases.
Similar with more cases:
- Other arthritis (FG)
- Polyarthropathies
- Finngen Rheumatological endpoints
- Arthropathies
- Diseases of the musculoskeletal system and connective tissue
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 9797 | 5674 | 4039 |
| Only index persons | 8477 | 5001 | 3476 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.14 | 0.16 | 0.11 |
| Only index persons | 0.16 | 0.18 | 0.13 |
| Median age at first event (years) | |||
| Whole population | 53.37 | 52.56 | 54.28 |
| Only index persons | 51.86 | 50.97 | 53.15 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1436 | 857 | 579 |
| Unadjusted period prevalence (%) | 0.28 | 0.29 | 0.26 |
| Median age at first event (years) | 51.31 | 47.84 | 56.45 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1321
- Matched controls
- 13210
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
102.7
323.0
463
69
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
63.9
323.0
600
170
M13.9
ICD-10 Finland
Arthritis, unspecified
102.8
323.0
489
75
A07EC01
ATC
sulfasalazine; oral, rectal
59.9
323.0
554
157
P01BA02
ATC
hydroxychloroquine; oral
71.7
323.0
527
121
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
88.9
323.0
433
72
M13.0
ICD-10 Finland
Polyarthritis, unspecified
4503599627370496.0
323.0
1151
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
78.2
323.0
760
225
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
3571.0
317.7
294
*
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
3032.9
278.0
259
*
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
146.5
258.6
269
23
H02AB06
ATC
prednisolone; systemic
7.5
240.0
979
3658
M17.1
ICD-10 Finland
Other primary gonarthrosis
20.6
179.7
277
168
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
400.8
179.1
176
5
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
91.5
178.2
196
25
L04AA13
ATC
leflunomide; oral
323.3
170.1
169
6
L88
ICPC
Rheumatoid/seropositive arthritis
60.3
167.5
196
38
M25.5
ICD-10 Finland
Pain in joint
6.6
166.5
513
1151
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
95.9
166.2
182
22
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
12.5
149.7
286
286
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
754.6
140.5
136
*
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
16.2
134.0
225
165
7165A
ICD-9 Finland
Other and unspecified arthropathies, Unspecified polyarthropathy or polyarthritis
+∞
126.1
119
*
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
88.5
115.5
128
16
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
13.2
115.4
212
189
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.9
108.7
618
2418
M07.3*L40.5
ICD-10 Finland
Other psoriatic arthropathies
+∞
100.3
95
*
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
264.2
97.0
98
*
M19.0
ICD-10 Finland
Primary arthrosis of other joints
27.2
97.0
135
55
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
13.1
91.5
167
144
M02.9
ICD-10 Finland
Reactive arthropathy, unspecified
170.3
91.4
95
6
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
928.4
89.8
87
*
TNG10
NOMESCO Finland
Puncture of knee
+∞
89.6
85
*
M16.1
ICD-10 Finland
Other primary coxarthrosis
32.5
87.5
116
39
M01CB01
ATC
sodium aurothiomalate; parenteral
+∞
86.4
82
*
H02AB07
ATC
prednisone; oral
4.9
84.0
316
802
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.2
83.8
690
3385
M01AH05
ATC
etoricoxib; oral
3.1
83.4
833
4665
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
105.9
82.0
89
9
L04AB01
ATC
etanercept; parenteral
104.6
81.0
88
9
NH3EA
NOMESCO Finland
Feet X-ray examination with load
99.6
76.9
84
9
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
11.3
75.7
148
146
N02AX02
ATC
tramadol; systemic, rectal
3.0
74.4
611
2915
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
102.1
70.7
77
8
L04AB04
ATC
adalimumab; parenteral
33.2
70.7
93
30
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
80.6
67.8
76
10
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
26.9
66.9
93
37
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
147.6
66.6
70
5
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
24.6
65.9
94
41
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
231.2
64.8
66
*
M10.9
ICD-10 Finland
Gout, unspecified
10.8
57.9
115
116
M13.1
ICD-10 Finland
Monoarthritis, not elsewhere classified
84.0
57.5
64
8
NF1AA
NOMESCO Finland
Hip X-ray examination
8.2
57.2
133
177
M01AC06
ATC
meloxicam; systemic, rectal
2.7
56.0
522
2568
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
+∞
55.6
53
*
NGB40
NOMESCO Finland
Primary total prosthetic replacement of knee joint with patellar part - sliding prosthesis
+∞
55.6
53
*
WX320
NOMESCO Finland
Spinalanesthesy
3.5
53.2
285
957
M01AH01
ATC
celecoxib; oral (coxibs)
3.6
53.1
278
918
M20.1
ICD-10 Finland
Hallux valgus (acquired)
14.5
52.5
90
66
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.5
52.2
611
3379
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
15.3
50.7
85
59
TNG11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in knee
+∞
49.3
47
*
A02BC02
ATC
pantoprazole; systemic
2.4
47.6
879
6018
M10.0
ICD-10 Finland
Idiopathic gout
18.1
47.2
74
43
ZXA00
NOMESCO Finland
Right side
2.8
46.7
376
1657
M06.4
ICD-10 Finland
Inflammatory polyarthropathy
473.5
46.6
46
*
M06.8
ICD-10 Finland
Other specified rheumatoid arthritis
473.5
46.6
46
*
M13.8
ICD-10 Finland
Other specified arthritis
48.6
46.4
56
12
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
48.6
46.4
56
12
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
19.9
46.2
70
37
M01CB03
ATC
auranofin; oral
+∞
46.1
44
*
ZXA05
NOMESCO Finland
Left side
2.8
45.6
355
1529
M45
ICD-10 Finland
Ankylosing spondylitis
13.4
45.3
80
63
M20.4
ICD-10 Finland
Other hammer toe(s) (acquired)
32.4
44.9
59
19
NHK30
NOMESCO Finland
Osteotomy or rotation osteotomy of first metatarsal or tarsal bone
452.1
44.5
44
*
M01AE02
ATC
naproxen; oral, rectal
2.3
43.9
757
4921
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
6.1
43.4
125
224
ZX140
NOMESCO Finland
Intra articular
441.3
43.4
43
*
L40.5
ICD-10 Finland
Arthropathic psoriasis
34.3
43.2
56
17
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
+∞
42.9
41
*
N02BE01
ATC
paracetamol; systemic, rectal
2.7
42.6
1115
8832
M04AA01
ATC
allopurinol; systemic
3.9
42.6
191
547
NG1DA
NOMESCO Finland
X-ray of knees
63.5
42.5
49
8
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
5.4
42.3
134
270
NK5AT
NOMESCO Finland
Joint injection with ultrasound guidance not elsewhere classified
221.9
42.1
43
*
N02AJ06
ATC
codeine and paracetamol; systemic
2.4
42.1
469
2451
M07.3
ICD-10 Finland
Other psoriatic arthropathies
419.9
41.3
41
*
M79.6
ICD-10 Finland
Pain in limb
2.4
40.3
458
2405
M01AH02
ATC
rofecoxib; oral
3.6
40.2
200
623
212
Kela drug reimbursment
Gout
+∞
39.8
38
*
L04AX01
ATC
azathioprine; systemic
6.6
39.5
106
173
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
24.3
39.5
56
24
NHG77
NOMESCO Finland
Arthroplasty of interphalangeal tarsal joint(s)
205.9
39.0
40
*
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
17.0
38.9
62
38
L04AB06
ATC
golimumab; parenteral
58.1
38.5
45
8
M35.3
ICD-10 Finland
Polymyalgia rheumatica
7.5
37.9
92
130
7140B
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SERONEGATIVA]
+∞
37.7
36
*
M00.9
ICD-10 Finland
Pyogenic arthritis, unspecified
+∞
37.7
36
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
4.0
37.1
160
440
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
46.5
37.1
45
10
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.6
35.3
298
1321
N03AX16
ATC
pregabalin; oral
2.5
35.0
318
1467
Z96.6
ICD-10 Finland
Presence of orthopaedic joint implants
80.4
35.0
39
5
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
11.5
35.0
66
60
J01DB01
ATC
cefalexin; oral
2.3
35.0
1071
8552
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.2
34.8
518
3040
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.5
34.8
177
559
71493
ICD-8 Finland
Other specified forms of arthritis, Polyarthritis chronica seronegativa
+∞
34.5
33
*
72410
ICD-8 Finland
Internal derangement of joint, Other shoulder derangement
+∞
34.5
33
*
B01AB05
ATC
enoxaparin; parenteral
2.4
34.5
363
1810
M05
ICD-10 Finland
Seropositive rheumatoid arthritis
345.5
34.1
34
*
NGF15
NOMESCO Finland
Total synovectomy of knee, arthroscopic
78.3
34.0
38
5
71107
ICD-8 Finland
Acute nonpyogenic arthritis, Loco multiplici
+∞
33.5
32
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.9
32.8
230
909
M09AX01
ATC
hyaluronic acid; parenteral
10.3
32.1
64
65
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
17.9
32.0
50
29
NH1AE
NOMESCO Finland
Ankle joint ultrasound examination
89.8
31.9
35
*
71239
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides NUD
+∞
31.4
30
*
M01AE03
ATC
ketoprofen; systemic, rectal
2.1
31.2
485
2864
NE1AA
NOMESCO Finland
Pelvis X-ray examination
5.6
30.9
93
176
R4110
NOMESCO Finland
Physiotherapy
2.3
30.5
361
1887
L04AA17
ATC
[U] adalimumab; parenteral
+∞
30.3
29
*
M01AX05
ATC
glucosamine; oral
2.9
30.3
205
788
L15
ICPC
Knee symptom/complaint
2.7
30.2
229
945
J01FF01
ATC
clindamycin; systemic
2.2
29.8
355
1857
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
8.2
29.6
67
85
M01AX17
ATC
nimesulide; oral
2.3
29.2
312
1548
R4120
NOMESCO Finland
Occupational therapy
4.1
29.2
118
305
M79.0
ICD-10 Finland
Rheumatism, unspecified
7.8
29.1
68
91
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
41.1
29.1
36
9
WX111
NOMESCO Finland
Local infiltration anesthesia
298.1
28.9
29
*
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
12.0
28.3
52
45
L04AA01
ATC
[U] ciclosporin; systemic
16.6
28.2
45
28
G56.0
ICD-10 Finland
Carpal tunnel syndrome
3.0
27.9
180
669
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
4.3
27.6
108
270
L90
ICPC
Osteoarthrosis of knee
7.5
27.5
66
92
M05BA04
ATC
alendronic acid; oral
3.4
27.4
142
452
XX9XE
NOMESCO Finland
Other ultrasound examination
30.8
27.3
36
12
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
4.7
27.1
95
213
L04AA11
ATC
[U] etanercept; parenteral
276.3
26.8
27
*
M19.2
ICD-10 Finland
Other secondary arthrosis
276.3
26.8
27
*
M06
ICD-10 Finland
Other rheumatoid arthritis
142.8
26.7
28
*
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
3.9
26.5
114
311
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.5
26.2
132
411
7151F
ICD-9 Finland
Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, primary[OSTEOARTHROSIS PRIMARIA, POLVI]
+∞
26.1
25
*
SPAT1202
SPAT
Intra-articular injection
8.1
25.9
59
76
A02BC03
ATC
lansoprazole; oral
2.1
25.9
373
2100
NHG76
NOMESCO Finland
Arthroplasty of other tarsometatarsal joint
265.4
25.8
26
*
WZA10
NOMESCO Finland
Long statement of health and health related matters
13.3
25.8
45
35
ZX120
NOMESCO Finland
Intravenous
2.9
25.7
166
617
NG1EA
NOMESCO Finland
Knee X-ray examination with wrench
137.6
25.7
27
*
NFB40
NOMESCO Finland
Primary total prosthetic replacement of hip joint using hybrid technique
29.0
25.4
34
12
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
14.3
25.4
43
31
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
12.2
25.3
46
39
N03AX12
ATC
gabapentin; oral
2.7
25.2
191
783
NDG30
NOMESCO Finland
Fusion of wrist, total
+∞
25.1
24
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.1
24.9
363
2050
M17.5
ICD-10 Finland
Other secondary gonarthrosis
71.3
24.9
28
*
M15.0
ICD-10 Finland
Primary generalized (osteo)arthrosis
13.4
24.8
43
33
H02AB04
ATC
methylprednisolone; systemic
2.6
24.6
201
858
M01AB55
ATC
diclofenac, combinations; oral
3.9
24.5
104
281
B01AX06
ATC
[U] rivaroxaban; oral
57.1
24.1
28
5
L20
ICPC
Joint symptom/complaint NOS
6.1
24.0
66
112
M01AB05
ATC
diclofenac; systemic, rectal
1.8
23.8
809
6139
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.1
23.5
336
1871
M16.9
ICD-10 Finland
Coxarthrosis, unspecified
8.4
23.5
52
64
UJF32
NOMESCO Finland
Coloscopy
2.1
23.4
330
1830
M02AA07
ATC
piroxicam; topical
1.9
23.3
439
2720
NHK40
NOMESCO Finland
Osteotomy or rotation osteotomy of II-V metatarsal or tarsal bone
55.0
23.1
27
5
TNB11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in shoulder joint
+∞
23.0
22
*
M01AE01
ATC
ibuprofen; systemic, rectal
2.1
22.7
1128
9700
M20.2
ICD-10 Finland
Hallux rigidus
122.1
22.6
24
*
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
22.3
288
1536
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.9
22.0
147
554
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
+∞
21.9
21
*
NHG24
NOMESCO Finland
Fusion of subtalar joint and between bones of ankle
+∞
21.9
21
*
1220
FHL
Arthroscopy
7.7
21.5
50
67
M17
ICD-10 Finland
Gonarthrosis [arthrosis of knee]
3.6
21.3
98
284
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
14.3
20.9
35
25
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
+∞
20.9
20
*
C03CA01
ATC
furosemide; systemic
2.0
20.9
337
1958
TNC11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in elbow joint
213.1
20.6
21
*
M02.8
ICD-10 Finland
Other reactive arthropathies
111.7
20.6
22
*
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
18.6
20.5
31
17
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
14.5
20.4
34
24
M22.4
ICD-10 Finland
Chondromalacia patellae
58.4
19.9
23
*
NDL52
NOMESCO Finland
Tenosynovectomy of hand
58.4
19.9
23
*
71238
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides alia definita
+∞
19.8
19
*
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.8
19.5
491
3313
SPAT1153
SPAT
Removal of sutures
1.9
19.4
370
2273
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
5.2
19.1
60
120
NF1DA
NOMESCO Finland
X-ray of hips
14.2
19.1
32
23
S18
ICPC
Laceration/cut
1.8
18.8
467
3124
H20.0
ICD-10 Finland
Acute and subacute iridocyclitis
4.4
18.8
69
163
M19.9
ICD-10 Finland
Arthrosis, unspecified
7.5
18.8
44
60
L13
ICPC
Hip symptom/complaint
2.5
18.8
160
694
J01MA02
ATC
ciprofloxacin; systemic
1.8
18.8
464
3103
ACC51
NOMESCO Finland
Release of median nerve
3.2
18.7
100
325
NFC20
NOMESCO Finland
Secondary implantation of hip prosthesis
39.0
18.6
23
6
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.1
18.2
223
1151
M23.8
ICD-10 Finland
Other internal derangements of knee
9.5
18.2
37
40
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.6
18.1
136
552
M17.3
ICD-10 Finland
Other post-traumatic gonarthrosis
33.4
18.0
23
7
L08
ICPC
Shoulder symptom/complaint
2.1
17.8
222
1157
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.5
17.8
148
633
7350A
ICD-9 Finland
Acquired deformities of toe, Hallux valgus (acquired)
+∞
17.7
17
*
NHG70
NOMESCO Finland
Arthroplasty of first tarsometatarsal joint
+∞
17.7
17
*
L04AA24
ATC
abatacept; parenteral
+∞
17.7
17
*
R50.9
ICD-10 Finland
Fever, unspecified
2.3
17.6
178
841
M54.5
ICD-10 Finland
Low back pain
1.8
17.5
377
2401
1221
FHL
Arthroscopy and meniscus surgery
13.3
17.5
30
23
M54.4
ICD-10 Finland
Lumbago with sciatica
2.2
17.4
193
954
J01DA01
ATC
[U] cefalexin; systemic
1.7
17.4
766
5999
B01AF01
ATC
rivaroxaban; oral
3.0
17.3
105
373
M01AB01
ATC
indometacin; systemic, rectal
3.1
17.3
99
338
9271
FHL
Hallux surgery
42.6
17.3
21
5
X59
ICD-10 Finland
Exposure to unspecified factor
2.1
17.3
209
1073
M01AX01
ATC
nabumetone; oral
4.4
17.2
63
149
WX002
NOMESCO Finland
Sedation and analgesia
2.0
17.1
233
1258
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
3.1
17.0
97
330
L17
ICPC
Foot/toe symptom/complaint
1.9
16.9
275
1586
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
4.5
16.7
60
139
TND10
NOMESCO Finland
Joint puncture, wrist or finger joint
+∞
16.7
16
*
L40.0
ICD-10 Finland
Psoriasis vulgaris
3.9
16.7
70
188
M15.8
ICD-10 Finland
Other polyarthrosis
15.3
16.7
27
18
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.8
16.6
337
2100
T84.5
ICD-10 Finland
Infection and inflammatory reaction due to internal joint prosthesis
27.9
16.5
22
8
A02BC01
ATC
omeprazole; systemic
1.8
16.5
330
2045
NK4AT
NOMESCO Finland
Puncture of joint with ultrasound guidance not elsewher classified
40.6
16.3
20
5
RT272
NOMESCO Finland
NA
40.6
16.3
20
5
M03BX02
ATC
tizanidine; oral
1.6
16.3
725
5653
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
10.5
16.2
31
30
M70.6
ICD-10 Finland
Trochanteric bursitis
2.5
16.2
134
574
N06AA09
ATC
amitriptyline; systemic
2.6
16.1
127
528
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
17.0
16.1
25
15
E0000UV
ATC
NA
1.7
16.0
478
3339
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
15.9
283
1683
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.0
15.8
92
318
M47.9
ICD-10 Finland
Spondylosis, unspecified
5.3
15.8
48
93
S83.2
ICD-10 Finland
Tear of meniscus, current
3.7
15.8
69
192
M19.8
ICD-10 Finland
Other specified arthrosis
6.4
15.7
41
66
L89
ICPC
Osteoarthrosis of hip
13.1
15.7
27
21
291
Kela drug reimbursment
Tofacitinib
+∞
15.6
15
*
7177A
ICD-9 Finland
Internal derangement of knee, Chondromalacia of patella
+∞
15.6
15
*
7168A
ICD-9 Finland
Other and unspecified arthropathies, Other specified arthropathy
+∞
15.6
15
*
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
4.5
15.6
56
130
NG2AA
NOMESCO Finland
Patella X-ray examination
13.9
15.5
26
19
M25.4
ICD-10 Finland
Effusion of joint
13.9
15.5
26
19
NF2AT
NOMESCO Finland
Injection to hip joint with ultrasound guidance
161.7
15.5
16
*
NHG82
NOMESCO Finland
Fusion of other tarsal joint
161.7
15.5
16
*
R06.0
ICD-10 Finland
Dyspnoea
1.8
15.3
283
1702
N02AA05
ATC
oxycodone; systemic
2.2
15.3
167
816
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
6.1
15.2
41
69
NE1BA
NOMESCO Finland
Pelvis extensive X-ray examination
23.7
15.1
21
9
J01AA02
ATC
doxycycline; systemic
1.7
15.1
958
8118
WZA90
NOMESCO Finland
Other doctors statement
1.9
14.8
251
1465
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.7
14.7
335
2154
7170A
ICD-9 Finland
Internal derangement of knee, Old bucket handle tear of medial meniscus
+∞
14.6
14
*
9256
FHL
Synovectomy (knee 9311)
+∞
14.6
14
*
73799
ICD-8 Finland
Hallux valgus and varus
+∞
14.6
14
*
M16.7
ICD-10 Finland
Other secondary coxarthrosis
81.0
14.6
16
*
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
151.5
14.5
15
*
M32.9
ICD-10 Finland
Systemic lupus erythematosus, unspecified
15.6
14.4
23
15
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.1
14.4
165
824
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
27.5
14.3
19
7
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.7
14.1
102
403
1223
FHL
Arthroscopy and articular cartilage surgery
42.9
14.1
17
*
L04AB05
ATC
certolizumab pegol; parenteral
42.9
14.1
17
*
NGF00
NOMESCO Finland
Excision of plica of synovy of knee
17.7
13.8
21
12
NA6AA
NOMESCO Finland
Sacro-iliac joint X-ray examination
53.9
13.8
16
*
J01FA06
ATC
roxithromycin; oral
1.6
13.7
479
3456
M48.0
ICD-10 Finland
Spinal stenosis
2.4
13.7
124
556
ND1AA
NOMESCO Finland
Wrist X-ray examination
3.0
13.6
80
280
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
4.8
13.6
45
97
NH3AE
NOMESCO Finland
Feet ultrasound examination
+∞
13.6
13
*
9311
FHL
Knee cleansing surgery (synovectomy, debridement)
+∞
13.6
13
*
NGC00
NOMESCO Finland
Exchange of a loose part of prosthesis in knee joint
+∞
13.6
13
*
D07AC01
ATC
betamethasone; topical
1.7
13.5
390
2670
NHG22
NOMESCO Finland
Fusion of subtalar joint
141.3
13.5
14
*
J45.9
ICD-10 Finland
Asthma, unspecified
1.9
13.4
207
1163
M21.4
ICD-10 Finland
Flat foot [pes planus] (acquired)
8.2
13.3
29
36
D64.9
ICD-10 Finland
Anaemia, unspecified
2.3
13.3
128
590
K07.60
ICD-10 Finland
Snapping jaw
3.4
13.2
64
195
NH1AD
NOMESCO Finland
Ankle and foot CT
5.9
13.2
36
62
NHL68
NOMESCO Finland
Tenodesis, shortening or lengthening of tendon of foot
40.5
13.2
16
*
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.3
13.1
125
574
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.3
13.1
66
207
A02BC05
ATC
esomeprazole; systemic
1.6
12.9
451
3239
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
7.0
12.9
31
45
L12
ICPC
Hand/finger symptom/complaint
2.1
12.9
159
819
NC1AA
NOMESCO Finland
Elbow X-ray examination without contrast
4.3
12.7
46
109
NDF60
NOMESCO Finland
Operation for osteochondritis of a joint of hand,v
70.5
12.6
14
*
NFB50
NOMESCO Finland
Primary total prosthetic replacement of hip joint using cement
70.5
12.6
14
*
H02AB08
ATC
triamcinolone; systemic
70.5
12.6
14
*
E000001
ATC
NA
1.8
12.6
242
1464
M02.3
ICD-10 Finland
Reiter disease
+∞
12.5
12
*
NHG20
NOMESCO Finland
Fusion of talocrural joint
131.1
12.4
13
*
M17.4
ICD-10 Finland
Other secondary gonarthrosis, bilateral
131.1
12.4
13
*
TNH10
NOMESCO Finland
Joint puncture, ankle joint or foot joint
131.1
12.4
13
*
ND1AE
NOMESCO Finland
Wrist ultrasound examination
37.9
12.2
15
*
NBB20
NOMESCO Finland
Primary total prosthetic replacement of humero-scapular joint
37.9
12.2
15
*
L03
ICPC
Low back symptom/complaint
1.7
12.1
262
1645
M35.7
ICD-10 Finland
Hypermobility syndrome
7.8
12.1
27
35
A46
ICD-10 Finland
Erysipelas
2.0
12.1
155
810
9273
FHL
Other surgery for toe deformity or pain condition, e.g., Morton, hammer toe
26.9
12.1
16
6
N06AX21
ATC
duloxetine; oral
2.2
12.0
120
564
R03AC02
ATC
salbutamol; inhalant
1.5
11.9
596
4635
L04AA29
ATC
tofacitinib; oral
47.1
11.9
14
*
1222
FHL
Arthroscopy and synovial surgery
47.1
11.9
14
*
NB2AT
NOMESCO Finland
Intra artrial injection of shoulder with ultrasound guidance
11.8
11.8
21
18
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
5.3
11.7
35
68
M18.1
ICD-10 Finland
Other primary arthrosis of first carpometacarpal joint
16.6
11.7
18
11
M03BC01
ATC
orphenadrine (citrate); systemic
1.7
11.7
259
1638
M15
ICD-10 Finland
Polyarthrosis
4.0
11.6
46
119
NHG26
NOMESCO Finland
Fusion between bones of ankle or ankle and foot
65.5
11.6
13
*
L04AC10
ATC
secukinumab; parenteral
65.5
11.6
13
*
RT271
NOMESCO Finland
NA
65.5
11.6
13
*
NDG76
NOMESCO Finland
Fusion of DIP joint
23.1
11.6
16
7
SPAT1229
SPAT
Assessment of need for aid
2.5
11.5
90
373
M07.5*K51.9
ICD-10 Finland
Arthropathy in ulcerative colitis
+∞
11.5
11
*
6960A
ICD-9 Finland
Psoriasis and similar disorders, Psoriatic arthropathy
+∞
11.5
11
*
L04AC07
ATC
tocilizumab; parenteral
+∞
11.5
11
*
M07.0*L40.5
ICD-10 Finland
Distal interphalangeal psoriatic arthropathy
121.0
11.4
12
*
NHF15
NOMESCO Finland
Synovectomy of ankle, arthroscopic
121.0
11.4
12
*
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.8
11.4
48
131
B01AB04
ATC
dalteparin; parenteral
3.0
11.4
66
229
J01CA04
ATC
amoxicillin; systemic
1.6
11.4
968
8433
R07.4
ICD-10 Finland
Chest pain, unspecified
1.7
11.4
286
1872
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
6.1
11.4
30
50
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
8.4
11.3
24
29
D05AX52
ATC
calcipotriol, combinations; topical
2.9
11.3
70
254
M71.2
ICD-10 Finland
Synovial cyst of popliteal space [Baker]
4.2
11.3
42
103
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
3.0
11.2
65
226
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.2
11.1
114
542
R60.0
ICD-10 Finland
Localized oedema
2.2
11.1
116
556
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.0
11.0
63
217
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.6
10.9
398
2866
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
10.8
643
5158
R06AE07
ATC
cetirizine; oral
1.5
10.7
500
3800
P01BA01
ATC
chloroquine; systemic
18.0
10.7
16
9
NHK99
NOMESCO Finland
Other operation on bone of ankle or foot
13.0
10.7
18
14
TQW40
NOMESCO Finland
Remowal of suture of skin
2.6
10.7
79
320
NDG60
NOMESCO Finland
Arthroplasty of first CMC joint
60.5
10.6
12
*
L04AD01
ATC
ciclosporin; systemic
5.4
10.6
31
59
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.0
10.5
142
758
L01CB
ATC
Podophyllotoxin derivatives
+∞
10.4
10
*
71490
ICD-8 Finland
Other specified forms of arthritis, Arthritis postinfectiosa NUD
+∞
10.4
10
*
NGF10
NOMESCO Finland
Total synovectomy of knee, open
+∞
10.4
10
*
M12.3
ICD-10 Finland
Palindromic rheumatism
+∞
10.4
10
*
M08.9
ICD-10 Finland
Juvenile arthritis, unspecified
+∞
10.4
10
*
D07AB02
ATC
hydrocortisone butyrate; topical
1.6
10.4
314
2153
B01AA03
ATC
warfarin; systemic
1.8
10.3
202
1226
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.9
10.3
152
839
X58
ICD-10 Finland
Exposure to other specified factors
2.0
10.3
136
718
R51.80
ICD-10 Finland
Headache
1.9
10.3
157
879
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.8
10.2
188
1120
M01AB08
ATC
etodolac; oral
2.4
10.2
82
348
D07AC13
ATC
mometasone; topical
1.6
10.1
330
2306
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.6
10.1
347
2456
L28
ICPC
Limited function/disability (L)
1.9
10.0
155
870
3005
Kela drug reimbursment
Tofacitinib
40.4
10.0
12
*
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.4
9.9
86
378
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
4.9
9.9
31
64
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.8
9.8
189
1140
ZXA10
NOMESCO Finland
Bilateral
1.7
9.8
197
1203
M01AE52
ATC
naproxen and esomeprazole; oral
4.0
9.7
38
98
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
2.6
9.7
69
272
S89.9
ICD-10 Finland
Unspecified injury of lower leg
3.8
9.7
40
108
NDU20
NOMESCO Finland
Removal of internal fixation device from wrist or hand
5.4
9.7
28
53
NF1AT
NOMESCO Finland
Puncture of hip joint with ultrasound guidance
55.4
9.7
11
*
9522
FHL
Synovectomy
55.4
9.7
11
*
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
2.6
9.6
71
286
M25.9
ICD-10 Finland
Joint disorder, unspecified
11.5
9.6
17
15
L16
ICPC
Ankle symptom/complaint
2.1
9.5
108
538
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
2.8
9.5
59
215
UGC12
NOMESCO Finland
Flexible bronchoscopy
2.2
9.4
93
435
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.5
9.4
465
3556
NGB10
NOMESCO Finland
Primary partial prosthetic replacement of knee joint, demi prosthesis
100.7
9.4
10
*
NDG74
NOMESCO Finland
Fusion of first IP joint
100.7
9.4
10
*
NFC40
NOMESCO Finland
Repair of hip prosthesis by bone transplant to acetabulum
100.7
9.4
10
*
RT350
NOMESCO Finland
NA
30.2
9.4
12
*
RT171
NOMESCO Finland
NA
30.2
9.4
12
*
M02.1
ICD-10 Finland
Postdysenteric arthropathy
+∞
9.4
9
*
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.9
9.3
136
745
N02AJ13
ATC
tramadol and paracetamol; systemic
5.8
9.2
25
44
M03BC51
ATC
orphenadrine, combinations; systemic
1.6
9.2
307
2150
S97
ICPC
Chronic ulcer skin
2.7
9.2
62
238
M01AC01
ATC
piroxicam; systemic, rectal
1.9
9.2
146
827
H04.10
ICD-10 Finland
Dry eye syndrome
2.0
9.1
115
597
J45.1
ICD-10 Finland
Nonallergic asthma
2.3
9.1
80
354
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
3.4
9.1
43
131
WX110
NOMESCO Finland
Local anesthesy
1.4
9.1
789
6718
J01FA10
ATC
azithromycin; systemic
1.4
9.0
657
5403
M43.1
ICD-10 Finland
Spondylolisthesis
3.3
9.0
44
137
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.6
9.0
228
1489
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.4
9.0
42
127
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.7
9.0
220
1422
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.7
8.9
180
1102
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
5.5
8.9
25
46
NH1EA
NOMESCO Finland
Ankle X-ray examination with load or wrench
24.2
8.9
12
5
R4180
NOMESCO Finland
Podiatric therapy
8.0
8.9
19
24
G56.2
ICD-10 Finland
Lesion of ulnar nerve
3.4
8.8
41
123
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.1
8.8
98
484
J01MA12
ATC
levofloxacin; systemic
1.7
8.8
199
1258
Y88.1
ICD-10 Finland
Sequelae of misadventures to patients during surgical and medical procedures
8.7
8.8
18
21
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
8.8
229
1505
WX204
NOMESCO Finland
Axillary plexus blockaced
3.5
8.8
39
113
M35.1
ICD-10 Finland
Other overlap syndromes
10.8
8.8
16
15
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.1
8.8
100
499
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
3.6
8.8
38
108
S01BA04
ATC
prednisolone; ophthalmic (corticosteroids, plain)
3.7
8.8
36
98
M15.4
ICD-10 Finland
Erosive (osteo)arthrosis
50.3
8.7
10
*
A02BA02
ATC
ranitidine; systemic
1.6
8.6
217
1410
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.7
8.6
173
1058
NJ3NA
NOMESCO Finland
Measurement of difference in extremity lengty with X-ray
16.4
8.6
13
8
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.6
8.5
209
1352
K07.65
ICD-10 Finland
Temporomandibular joint-pain-dysfunction syndrome
9.0
8.5
17
19
M02AA10
ATC
ketoprofen; topical
1.8
8.5
158
942
NBF15
NOMESCO Finland
Humeroscapular synovectomy, arthroscopic
27.7
8.5
11
*
71599
ICD-8 Finland
Arthritis, unspecified
20.2
8.5
12
6
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
8.5
718
6045
M05BA07
ATC
risedronic acid; oral
3.2
8.4
43
139
NDF10
NOMESCO Finland
Synovectomy of wrist
90.6
8.4
9
*
4AC07
NOMESCO Finland
NA
90.6
8.4
9
*
M11.2
ICD-10 Finland
Other chondrocalcinosis
90.6
8.4
9
*
Z50.1
ICD-10 Finland
Other physical therapy
2.6
8.4
59
234
ZZH31
NOMESCO Finland
Bone allograft, small pieces
12.8
8.4
14
11
ZX100
NOMESCO Finland
Oral
5.1
8.3
25
50
L04AA37
ATC
baricitinib; oral
+∞
8.3
8
*
7354A
ICD-9 Finland
Acquired deformities of toe, Other hammer toe (acquired)
+∞
8.3
8
*
M01CC01
ATC
penicillamine; oral
+∞
8.3
8
*
7174A
ICD-9 Finland
Internal derangement of knee, Derangement of lateral meniscus
+∞
8.3
8
*
NGC20
NOMESCO Finland
Secondary implantation of prosthesis in knee joint, normal prosthesis
+∞
8.3
8
*
M23.4
ICD-10 Finland
Loose body in knee
+∞
8.3
8
*
3006
Kela drug reimbursment
Baricitinib
+∞
8.3
8
*
Y83.1
ICD-10 Finland
Surgical operation with implant of artificial internal device as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
8.6
8.3
17
20
I80.3
ICD-10 Finland
Phlebitis and thrombophlebitis of lower extremities, unspecified
3.0
8.3
45
152
H20.1
ICD-10 Finland
Chronic iridocyclitis
5.9
8.3
22
38
1225
FHL
Arthroscopy and other therapeutic procedure
10.8
8.3
15
14
C07AB07
ATC
bisoprolol; oral
1.4
8.3
507
4018
J01CF02
ATC
cloxacillin; systemic
3.7
8.3
34
93
SPAT1310
SPAT
Counselling related to known health issue
1.5
8.2
349
2571
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
6.5
8.2
20
31
SPAT1301
SPAT
No procedures
1.5
8.2
341
2504
NB1BG
NOMESCO Finland
Shoulder and humerus MRI examination with high intensity magnet
5.4
8.2
23
43
N06AX11
ATC
mirtazapine; oral
1.5
8.1
343
2521
L11
ICPC
Wrist symptom/complaint
2.1
8.1
86
416
RF210
NOMESCO Finland
NA
3.6
8.1
35
100
NG2CA
NOMESCO Finland
X-ray of patella with specialised projection
33.5
8.1
10
*
NHK10
NOMESCO Finland
Incision or excision of metatarsal or tarsal bone
17.3
8.1
12
7
C08CA05
ATC
nifedipine; systemic
2.3
8.1
71
316
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
2.8
8.0
48
173
M81.4
ICD-10 Finland
Drug-induced osteoporosis
22.2
8.0
11
5
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.4
8.0
605
4970
M65.8
ICD-10 Finland
Other synovitis and tenosynovitis
4.2
8.0
29
71
WZC30
NOMESCO Finland
Teaching
1.8
8.0
148
879
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.6
8.0
55
215
WX408
NOMESCO Finland
General anesthesy, balanced
1.5
7.9
288
2049
I50.9
ICD-10 Finland
Heart failure, unspecified
1.8
7.9
132
759
SPAT1254
SPAT
Administration of medicine
1.7
7.9
154
929
S01BA01
ATC
dexamethasone; ophthalmic (corticosteroids, plain)
3.0
7.9
45
155
TPH07
NOMESCO Finland
Cathetrisation of artery
1.9
7.9
119
660
N05CF01
ATC
zopiclone; oral
1.5
7.8
346
2567
UKC02
NOMESCO Finland
Cystoscopy
1.7
7.8
163
1008
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
7.8
459
3601
WX200
NOMESCO Finland
Interscalenous plexus blockade
5.1
7.7
23
46
9503
FHL
Tendon or tendon sheath cleansing surgery (tenosynovectomy)
45.2
7.7
9
*
ND2CG
NOMESCO Finland
Extensive MRI of hand
45.2
7.7
9
*
XG470
NOMESCO Finland
Measurement of diffusion capastity of the lungs
3.2
7.7
38
121
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
3.2
7.7
38
121
K02.1
ICD-10 Finland
Caries of dentine
1.4
7.7
626
5202
N02AC04
ATC
dextropropoxyphene; oral
3.0
7.7
41
138
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.4
7.7
63
272
D05AX02
ATC
calcipotriol; topical
3.0
7.6
42
144
M79.7
ICD-10 Finland
Fibromyalgia
3.5
7.6
34
100
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.6
7.6
54
216
A01
ICPC
Pain general/multiple sites
2.2
7.6
76
360
NHL50
NOMESCO Finland
Tenolysis or tenosynovectomy of foot
18.5
7.6
11
6
SPAT1255
SPAT
Intravenous administration of medicine
2.2
7.6
71
327
D07XC01
ATC
betamethasone, combinations; topical
1.8
7.6
122
695
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
3.3
7.5
36
112
P01AB01
ATC
metronidazole; oral, rectal
1.4
7.5
436
3407
WZA00
NOMESCO Finland
Short statement of of health and health related matters
2.5
7.5
56
230
J01MA14
ATC
moxifloxacin; systemic
2.0
7.5
97
511
J01FA09
ATC
clarithromycin; systemic
1.5
7.5
343
2561
J02AC01
ATC
fluconazole; systemic
1.4
7.5
432
3369
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.4
7.4
59
251
A28
ICPC
Limited function/disability NOS
1.7
7.4
143
860
ND2AE
NOMESCO Finland
Hand and fingers ultrasound examination
80.5
7.4
8
*
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.5
7.4
296
2147
L03.0
ICD-10 Finland
Cellulitis of finger and toe
2.2
7.4
72
338
L01
ICPC
Neck symptom/complaint
1.7
7.4
141
849
M25.2
ICD-10 Finland
Flail joint
+∞
7.3
7
*
TNF11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in hip joint
+∞
7.3
7
*
9279
FHL
Other measure in this category
+∞
7.3
7
*
M06.1
ICD-10 Finland
Adult-onset Still disease
+∞
7.3
7
*
NFB99
NOMESCO Finland
Other primary prosthetic replacement of hip joint
+∞
7.3
7
*
NDB78
NOMESCO Finland
Prosthetic replacement of several of finger or metacarpal
+∞
7.3
7
*
293
Kela drug reimbursment
Baricitinib
+∞
7.3
7
*
7166A
ICD-9 Finland
Other and unspecified arthropathies, Unspecified monoarthritis
+∞
7.3
7
*
M00.0
ICD-10 Finland
Staphylococcal arthritis and polyarthritis
+∞
7.3
7
*
NCF10
NOMESCO Finland
Synovectomy of elbow joint, open
+∞
7.3
7
*
NGC30
NOMESCO Finland
Secondary implantation of prosthesis in knee joint, special prosthesis
+∞
7.3
7
*
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.4
7.3
582
4803
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.4
7.3
525
4258
Z71.8
ICD-10 Finland
Other specified counselling
1.5
7.3
248
1739
M24.2
ICD-10 Finland
Disorder of ligament
15.8
7.2
11
7
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
5.5
7.2
20
37
M76.9
ICD-10 Finland
Enthesopathy of lower limb, unspecified
5.8
7.2
19
33
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
7.2
432
3389
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.4
7.2
558
4580
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.5
7.2
54
223
4AA12
NOMESCO Finland
NA
20.1
7.1
10
5
NDG20
NOMESCO Finland
Fusion of wrist, partial
20.1
7.1
10
5
9255
FHL
Joint auger removal
20.1
7.1
10
5
R05
ICD-10 Finland
Cough
1.6
7.1
206
1386
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.4
7.1
358
2719
R01AD09
ATC
mometasone; nasal
1.4
7.1
476
3811
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.7
7.1
153
956
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
3.4
7.0
32
96
M81.9
ICD-10 Finland
Osteoporosis, unspecified
2.7
7.0
45
168
E66.01
ICD-10 Finland
Obesity due to excess calories
2.1
7.0
72
346
J04AB02
ATC
rifampicin; systemic
7.0
7.0
16
23
R02
ICPC
Shortness of breath/dyspnoea
1.8
7.0
121
707
R5599
NOMESCO Finland
Other rehabilitation service
3.4
6.9
31
92
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
5.5
6.9
19
35
AN1
HP
Coronary angiography
1.8
6.9
118
684
J01DA06
ATC
[U] cefuroxime; systemic
1.7
6.9
159
1009
C08CA13
ATC
lercanidipine; oral
1.7
6.9
135
820
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
6.9
406
3170
D07AD01
ATC
clobetasol; topical
1.6
6.8
160
1018
NBL00
NOMESCO Finland
Suture or reinsertation of rotator cuff of shoulder
2.5
6.8
49
198
M10
ICD-10 Finland
Gout
2.9
6.8
40
143
9243
FHL
Plastic of the patella and its tendons
11.0
6.8
12
11
NBG00
NOMESCO Finland
Plastic operation on acromioclavicular joint
11.0
6.8
12
11
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.7
6.8
158
1004
NH1DG
NOMESCO Finland
Ankle and foot very extensive MRI examination with high intensity magnet
40.2
6.8
8
*
M15.3
ICD-10 Finland
Secondary multiple arthrosis
40.2
6.8
8
*
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
2.1
6.8
68
325
205
Kela drug reimbursment
Chronic hypertension
1.5
6.7
280
2044
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.5
6.7
259
1861
X50
ICD-10 Finland
Overexertion and strenuous or repetitive movements
4.1
6.7
24
59
SPAT1263
SPAT
Sampling
1.4
6.7
449
3583
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.9
6.7
89
476
M65.9
ICD-10 Finland
Synovitis and tenosynovitis, unspecified
3.3
6.7
31
95
M01AB16
ATC
aceclofenac; oral
3.0
6.7
36
123
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.5
6.6
219
1521
D07AA02
ATC
hydrocortisone; topical
1.7
6.6
147
923
TNX92
NOMESCO Finland
Supporting bandage or orthosis of lower limb
4.2
6.6
23
55
R42
ICD-10 Finland
Dizziness and giddiness
1.5
6.6
213
1472
M18.0
ICD-10 Finland
Primary arthrosis of first carpometacarpal joints, bilateral
12.3
6.6
11
9
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.0
6.6
82
428
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.7
6.6
127
766
M19
ICD-10 Finland
Other arthrosis
4.8
6.5
20
42
ND1CG
NOMESCO Finland
Wrist and hand extensive MRI examination with high intensity magnet
10.1
6.5
12
12
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
3.2
6.5
31
97
L18
ICPC
Muscle pain
2.6
6.5
43
166
L99
ICPC
Musculoskeletal disease other
4.2
6.5
23
56
M05BB03
ATC
alendronic acid and colecalciferol; oral
3.2
6.5
32
103
M01AH03
ATC
valdecoxib; oral
2.2
6.5
60
274
M66.0
ICD-10 Finland
Rupture of popliteal cyst
6.2
6.5
16
26
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.5
6.5
213
1480
AA1AD
NOMESCO Finland
CT of head and brain
1.5
6.5
240
1711
NHB10
NOMESCO Finland
Primary partial prosthetic replacement of ankle joint
70.1
6.4
7
*
ND1BG
NOMESCO Finland
Wrist and hand MRI examination with high intensity magnet
7.4
6.4
14
19
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
2.4
6.4
49
205
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.9
6.4
90
489
R2110
NOMESCO Finland
Giving the first information
2.0
6.4
80
417
SPAT1312
SPAT
General health counselling
1.4
6.4
343
2627
R60.9
ICD-10 Finland
Oedema, unspecified
2.4
6.3
52
226
L04AA06
ATC
mycophenolic acid; systemic
3.9
6.3
24
63
M25.0
ICD-10 Finland
Haemarthrosis
18.1
6.3
9
5
M07.0
ICD-10 Finland
Distal interphalangeal psoriatic arthropathy
+∞
6.3
6
*
NDG77
NOMESCO Finland
Other excision, reconstruction or fusion of joint of first finger
+∞
6.3
6
*
M16.6
ICD-10 Finland
Other secondary coxarthrosis, bilateral
+∞
6.3
6
*
M03.2*A04.6
ICD-10 Finland
Postinfectious arthropathy in enteritis due to Yersinia enterocolitica
+∞
6.3
6
*
TEG00
NOMESCO Finland
Punction of mandibular joint
+∞
6.3
6
*
NGC60
NOMESCO Finland
Exchange or addition of patellar part
+∞
6.3
6
*
NDB60
NOMESCO Finland
Prosthetic replacement of MCP joint of finger
+∞
6.3
6
*
NE1AD
NOMESCO Finland
Pelvis and hip bones CT examination
4.3
6.2
21
49
M79.1
ICD-10 Finland
Myalgia
1.7
6.2
127
779
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
6.2
791
6956
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.5
6.2
186
1264
B01AE07
ATC
dabigatran etexilate; oral
2.6
6.1
41
160
RF220
NOMESCO Finland
NA
4.7
6.1
19
41
M80.4
ICD-10 Finland
Drug-induced osteoporosis with pathological fracture
12.6
6.1
10
8
JN4BD
NOMESCO Finland
Extensive body CT
1.7
6.1
121
737
K07
ICPC
Swollen ankles/oedema
2.5
6.1
44
180
M23.3
ICD-10 Finland
Other meniscus derangements
8.6
6.1
12
14
SPAT1104
SPAT
Monitoring of emergency patient
2.0
6.0
69
348
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.6
6.0
141
898
NBA30
NOMESCO Finland
Exploration of joint of shoulder or upper arm, arthroscopic
3.6
6.0
25
71
Mortality – FinRegistry
↥Association
Association between endpoint M13_POLYARTHRITIS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_POLYARTHRITIS | 1.314 [1.18, 1.47] | < 0.001 |
| Birth year | 0.992 [0.98, 1.0] | 0.072 |
During the follow-up period (1.1.1998 — 31.12.2019), 742 out of 3877 females with M13_POLYARTHRITIS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_POLYARTHRITIS | 1.534 [1.36, 1.73] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.015 |
During the follow-up period (1.1.1998 — 31.12.2019), 723 out of 2820 males with M13_POLYARTHRITIS died.
Mortality risk
Mortality risk for people of age
years, who have M13_POLYARTHRITIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.092% | 0.25% |
| 5 | 0.742% | 1.823% |
| 10 | 1.726% | 4.371% |
| 15 | 3.488% | 8.113% |
| 20 | 6.128% | 13.419% |
Relationships between endpoints
↥Index endpoint: M13_POLYARTHRITIS – Polyarthritis, unspecified
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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