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Asthma (mode)

ASTHMA_MODE

asthma: A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors resulting in recurring periods of wheezing (a whistling sound while breathing), chest tightness, shortness of breath, mucus production and coughing. The symptoms appear due to a variety of triggers such as allergens, irritants, respiratory infections, weather changes, exercise, stress, reflux disease, medications, foods and emotional anxiety.

Endpoint definition

FinnGen phenotype data

414262 individuals

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Apply sex-specific rule None

414262

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Check conditions None

414262

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Check pre-conditions, main-only, mode, registry filters

Check mode of ICD-10 codes: %J45|J46
Hospital Discharge: ICD-10 J45, J46
Hospital discharge: ICD-9 493
Hospital discharge: ICD-8 493
Cause of death: ICD-10 J45, J46
Cause of death: ICD-9 493
Cause of death: ICD-8 493

2 out of 7 registries used, show all original rules.

43166

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Check minimum number of events None

43166

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Include endpoints None

43166

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Remove individuals based on genotype QC

39430

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ASTHMA_MODE

Control definitions

Control exclude ILD_DIFF_DG

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 39430 24877 14553
Unadjusted prevalence (%) 10.46 11.80 8.75
Mean age at first event (years) 43.78 42.85 45.35

Mortality

Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.

Correlations

Index endpoint: ASTHMA_MODE – Asthma (mode)
GWS hits:

Survival analyses between endpoints

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Asthma (mode)

Not a core endpoint, no data to show.