Anaemia in chronic diseases classified elsewhere

D3_ANAEMIAINCHRONICDISEASE

anemia (phenotype): ['A reduction in the number of circulating erythrocytes or in the quantity of hemoglobin.']

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 D63*
  • Cause of death: ICD-10 D63*

2 out of 7 registries used, show all original rules.

838

4. Check minimum number of events

None

838

5. Include endpoints

None

838

6. Filter based on genotype QC (FinnGen only)

838

Control definitions (FinnGen only)

Control exclude
D3_APLASTICANDOTHANAEMIA

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 5226 2347 2830
Only index persons 4405 1950 2455
Unadjusted period prevalence (%)
Whole population 0.07 0.07 0.08
Only index persons 0.08 0.07 0.09
Median age at first event (years)
Whole population 73.92 74.67 73.28
Only index persons 73.78 74.70 73.06

-FinnGen-

Key figures

All Female Male
Number of individuals 838 312 526
Unadjusted period prevalence (%) 0.19 0.11 0.23
Median age at first event (years) 69.37 66.54 71.05

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
749
Matched controls
7489
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
187.4
323.0
425
52
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
82.0
297.1
327
70
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
33.2
290.3
403
254
D63.8
ICD-10 Finland
Anaemia in other chronic diseases classified elsewhere
+∞
276.7
248
*
B03XA02
ATC
darbepoetin alfa; parenteral
103.9
264.1
281
43
D64.9
ICD-10 Finland
Anaemia, unspecified
43.7
245.0
307
117
N18.8
ICD-10 Finland
Other chronic renal failure
48.4
238.3
291
97
TK800
NOMESCO Finland
Hemodialysis
67.6
216.8
247
54
A11CC03
ATC
alfacalcidol; systemic
54.4
212.2
252
69
N25.8
ICD-10 Finland
Other disorders resulting from impaired renal tubular function
345.0
188.3
183
7
C03CA01
ATC
furosemide; systemic
10.7
185.5
562
1645
Z49.1
ICD-10 Finland
Extracorporeal dialysis
79.7
183.6
204
35
N18.0
ICD-10 Finland
End-stage renal disease
78.8
166.0
185
31
A12AA04
ATC
calcium carbonate; oral
54.6
154.3
183
44
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
84.2
153.9
170
26
D638, N189
ICD-10 Finland
NA
+∞
150.2
139
*
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
77.9
143.1
160
26
Z49.0
ICD-10 Finland
Preparatory care for dialysis
97.5
137.3
149
19
V03AE01
ATC
polystyrene sulfonate; oral
84.2
134.7
149
22
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
132.1
133.4
140
13
WW500
NOMESCO Finland
Blood transfusion
24.7
127.6
185
98
Z94.0
ICD-10 Finland
Kidney transplant status
68.8
127.2
145
26
D638, N188
ICD-10 Finland
NA
+∞
122.3
114
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
8.6
112.7
281
486
L04AA06
ATC
mycophenolic acid; systemic
49.6
111.8
135
33
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
187.7
109.6
112
7
127
Kela drug reimbursment
Transplant complication
44.6
107.8
133
36
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
12.1
105.9
208
231
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
102.2
104.4
113
13
Z49.2
ICD-10 Finland
Other dialysis
148.9
98.8
103
8
137
Kela drug reimbursment
Uraemia requiring dialysis
81.1
94.2
105
15
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
82.1
89.9
100
14
A49.9
ICD-10 Finland
Bacterial infection, unspecified
7.3
88.7
245
470
B05DA
ATC
Isotonic solutions
116.3
86.1
92
9
ZX120
NOMESCO Finland
Intravenous
8.0
84.9
215
360
V03AE02
ATC
sevelamer; oral
163.7
84.0
87
6
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
142.2
84.0
88
7
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
155.2
79.8
83
6
D638, N180
ICD-10 Finland
NA
+∞
77.5
73
*
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
29.3
76.4
104
41
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
45.9
76.0
93
23
C08CA01
ATC
amlodipine; oral
4.2
75.5
459
2033
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
33.0
74.3
98
34
D63.0
ICD-10 Finland
Anaemia in neoplastic disease
+∞
74.2
70
*
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
8.5
73.0
173
255
B05DB
ATC
Hypertonic solutions
107.1
71.4
77
8
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
46.1
70.3
86
21
TPX10
NOMESCO Finland
Implantation of vascular injection port
17.3
70.3
114
77
205
Kela drug reimbursment
Chronic hypertension
4.1
69.5
405
1680
M04AA01
ATC
allopurinol; systemic
5.3
69.2
250
645
N19
ICD-10 Finland
Unspecified kidney failure
12.4
68.2
128
122
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
4.1
67.9
375
1472
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
58.7
67.5
79
15
TK820
NOMESCO Finland
Peritoneal dialysis
189.6
67.2
69
*
196
Kela drug reimbursment
Paricalcitol and cinacalcet
96.4
64.1
70
8
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.8
64.0
477
2379
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
7.7
62.5
157
249
JN3AD
NOMESCO Finland
Abdominal CT examination
7.6
62.5
158
253
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
4.0
62.5
344
1319
TPH04
NOMESCO Finland
Cathetrisation of vein
4.3
62.3
291
961
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
6.9
62.2
171
309
KA2AT
NOMESCO Finland
Biopsy of transplanted kidney with ultrasound guidance
70.0
61.5
70
11
TJA35
NOMESCO Finland
Removal of peritoneal dialysis catheter
171.6
60.9
63
*
SPAT1262
SPAT
Handing over of treatment supplies
4.4
59.7
266
833
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.5
57.9
247
738
B03XA01
ATC
erythropoietin; parenteral
48.1
57.8
70
16
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
4.0
57.0
294
1046
N08.39
ICD-10 Finland
Glomerular disorders in diabetes mellitus microalbuminuria
60.1
56.7
66
12
TK810
NOMESCO Finland
Hemofiltration
58.1
54.7
64
12
N17.9
ICD-10 Finland
Acute renal failure, unspecified
9.8
54.6
116
138
A10AE04
ATC
insulin glargine; parenteral
5.8
53.4
168
356
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
49.9
53.3
64
14
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
5.7
53.0
169
364
L04AD01
ATC
ciclosporin; systemic
20.6
51.8
78
42
PB1DE
NOMESCO Finland
Upper extremity arteries ultrasound examination with Doppler method
189.8
51.6
53
*
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
7.3
51.2
132
214
N02AA05
ATC
oxycodone; systemic
4.3
50.7
221
662
D64.8
ICD-10 Finland
Other specified anaemias
31.8
50.6
67
23
E11.2
ICD-10 Finland
Type 2 diabetes mellitus, with renal complications
10.2
50.1
103
115
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
6.0
50.0
150
298
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
28.6
50.0
68
26
I50.9
ICD-10 Finland
Heart failure, unspecified
4.1
48.6
228
727
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
95.0
48.5
53
6
A10AE05
ATC
insulin detemir; parenteral
7.8
48.3
118
176
H05BX01
ATC
cinacalcet; oral
48.2
48.0
58
13
U14
ICPC
Kidney symptom/complaint
20.0
46.8
71
39
B01AB10
ATC
tinzaparin; parenteral
7.1
46.6
122
201
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
8.4
46.6
108
148
FM1LE
NOMESCO Finland
Combined ultrasound and EKG examination of heart with tolerance test
53.8
46.5
55
11
PG5DE
NOMESCO Finland
Ultrasound examination of injection gate to artery or vein with Doppler method
107.0
46.4
50
5
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
7.1
45.9
120
197
H3603, E103
ICD-10 Finland
NA
32.5
45.6
60
20
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
9.4
45.6
98
118
I12.0
ICD-10 Finland
Hypertensive renal disease with renal failure
26.9
44.9
62
25
H02AB04
ATC
methylprednisolone; systemic
4.2
44.9
198
591
103
Kela drug reimbursment
Diabetes, insulin-treated
3.2
44.2
319
1412
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
10.4
43.9
89
96
A41.9
ICD-10 Finland
Sepsis, unspecified
10.0
43.0
89
100
321
Kela drug reimbursment
Paricalcitol and cinacalcet
38.7
42.8
54
15
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
15.3
42.3
71
51
215
Kela drug reimbursment
Diabetes, non-insulin-treated
3.2
41.6
279
1160
C02AC05
ATC
moxonidine; oral
7.2
40.9
104
163
T89
ICPC
Diabetes insulin dependent
9.9
40.9
85
96
A02BC02
ATC
pantoprazole; systemic
3.0
40.7
550
3595
N25.0
ICD-10 Finland
Renal osteodystrophy
68.2
39.5
45
7
J01MA12
ATC
levofloxacin; systemic
3.4
38.8
231
869
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
3.9
38.6
182
568
XW000
NOMESCO Finland
Bone marrow biopsy
8.4
38.5
88
117
R50.9
ICD-10 Finland
Fever, unspecified
3.9
38.4
181
565
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
6.4
37.9
105
185
C07AG02
ATC
carvedilol; oral
5.5
37.5
120
253
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.8
37.2
135
327
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
6.2
37.1
106
194
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
10.4
36.9
74
78
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
7.0
36.7
95
152
3025
Kela drug reimbursment
Calcium carbonate
72.1
36.3
41
6
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
102.7
36.1
39
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
10.5
35.6
71
74
I10
ICD-10 Finland
Essential (primary) hypertension
2.7
34.6
538
3622
PBL09
NOMESCO Finland
Construction of arteriovenous fistula from brachial artery
94.5
33.0
36
*
V03AE03
ATC
lanthanum carbonate; oral
177.8
33.0
34
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.2
32.8
203
774
J01MA02
ATC
ciprofloxacin; systemic
2.6
32.8
372
2072
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
7.8
32.3
77
109
JN4AD
NOMESCO Finland
Body CT examination
4.6
32.3
122
306
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
6.5
32.1
87
148
C09AA02
ATC
enalapril; systemic
2.9
31.6
243
1068
UJF32
NOMESCO Finland
Coloscopy
2.8
31.3
262
1214
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
9.1
31.1
67
80
C07AB07
ATC
bisoprolol; oral
2.5
31.1
451
2836
A10AA01
ATC
NA
9.9
30.7
63
69
H36.03
ICD-10 Finland
Proliferative diabetic retinopathy
28.8
30.5
41
15
J01FF01
ATC
clindamycin; systemic
2.7
30.5
262
1228
R4110
NOMESCO Finland
Physiotherapy
2.7
30.0
269
1293
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
22.7
29.9
43
20
ZXD05
NOMESCO Finland
Urgent procedure
2.6
29.8
298
1524
A10AA02
ATC
NA
7.3
29.5
73
109
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
7.6
29.4
71
102
XCK10
NOMESCO Finland
Photography of fundus of eye
3.6
29.4
146
467
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.7
29.2
264
1271
CKC12
NOMESCO Finland
Photocoagulation of retina
6.4
29.2
80
138
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.7
29.1
253
1190
WX202
NOMESCO Finland
Supraclavicular plexus blockade
13.7
28.8
50
39
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
11.6
28.7
54
50
E87.5
ICD-10 Finland
Hyperkalaemia
11.6
28.7
54
50
M10.3
ICD-10 Finland
Gout due to impairment of renal function
50.7
28.6
34
7
N02AX02
ATC
tramadol; systemic, rectal
2.4
28.5
373
2184
L04AX01
ATC
azathioprine; systemic
6.6
28.2
75
124
A46
ICD-10 Finland
Erysipelas
3.2
28.2
167
609
H3601, E103
ICD-10 Finland
NA
23.4
28.1
40
18
306
Kela drug reimbursment
Erythropoietin and darbepoetin
150.6
27.8
29
*
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
26.6
27.7
38
15
3AC01
NOMESCO Finland
NA
20.6
27.7
41
21
Q61.2
ICD-10 Finland
Polycystic kidney, autosomal dominant
36.6
27.6
35
10
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
2.5
27.4
296
1561
WX408
NOMESCO Finland
General anesthesy, balanced
2.6
27.3
264
1309
I50.0
ICD-10 Finland
Congestive heart failure
4.0
27.1
117
330
Z51.5
ICD-10 Finland
Palliative care
4.6
26.7
98
237
K92.1
ICD-10 Finland
Melaena
5.2
26.6
86
181
H3600, E103
ICD-10 Finland
NA
19.1
26.4
40
22
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
3.5
26.3
138
458
M10.9
ICD-10 Finland
Gout, unspecified
4.3
26.0
104
273
PB1BC
NOMESCO Finland
Extensive angiography of upper extremity with X-ray
269.4
25.9
26
*
OAB74
NOMESCO Finland
Nutritional guidance related to treatment and rehabilitation for medical condition
52.0
25.4
30
6
J01MA14
ATC
moxifloxacin; systemic
3.6
24.9
120
372
H36.01
ICD-10 Finland
Diabetic maculopathy
14.3
24.8
42
31
D62
ICD-10 Finland
Acute posthaemorrhagic anaemia
134.5
24.7
26
*
H04AA01
ATC
glucagon; nasal, parenteral
10.2
24.6
49
51
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.7
24.5
200
888
J01DB01
ATC
cefalexin; oral
2.6
24.4
621
4875
K65.0
ICD-10 Finland
Acute peritonitis
17.3
24.3
38
23
H43.1
ICD-10 Finland
Vitreous haemorrhage
8.9
24.2
52
62
H36.09*E10.3
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic retinopathy
26.5
24.1
33
13
B82
ICPC
Anaemia other/unspecified
9.3
23.9
50
57
N17.8
ICD-10 Finland
Other acute renal failure
17.6
23.8
37
22
PBU84
NOMESCO Finland
Plastic repair of arteriovenous fistula from artery of upper extremity
129.1
23.7
25
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.6
23.7
114
352
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
5.0
23.6
79
173
C10AA05
ATC
atorvastatin; oral
2.2
23.5
358
2184
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.2
23.3
326
1912
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
8.0
23.0
53
71
KBV00
NOMESCO Finland
Insertion of stent into ureter
19.7
22.8
34
18
PB1AC
NOMESCO Finland
Angiography of upper extremity with X-ray
123.8
22.7
24
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.3
22.7
307
1766
KA1AE
NOMESCO Finland
Kidney ultrasound examination
7.9
22.5
52
70
L04AA01
ATC
[U] ciclosporin; systemic
14.9
22.3
37
26
A04AA01
ATC
ondansetron; systemic, rectal
4.4
22.0
84
210
N03.9
ICD-10 Finland
Chronic nephritic syndrome, unspecified
30.1
22.0
29
10
S97
ICPC
Chronic ulcer skin
4.6
21.9
79
187
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
3.3
21.8
120
409
N13.3
ICD-10 Finland
Other and unspecified hydronephrosis
8.1
21.6
49
64
PC5DE
NOMESCO Finland
Ultrasound of kidney circulation with Doppler technic
44.8
21.5
26
6
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.8
21.3
160
672
Z3231
NOMESCO Finland
Registered nurse
2.3
21.2
261
1424
TPH07
NOMESCO Finland
Cathetrisation of artery
3.1
20.9
125
451
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.8
20.9
150
610
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
3.2
20.9
120
421
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.9
20.8
89
248
WZC30
NOMESCO Finland
Teaching
2.9
20.7
141
556
R18
ICD-10 Finland
Ascites
9.6
20.6
42
46
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
4.1
20.4
82
216
H02AB06
ATC
prednisolone; systemic
2.1
20.3
376
2447
CKD05
NOMESCO Finland
Puncture of vitreous body with injection of medication
4.4
20.2
77
192
SPAT1255
SPAT
Intravenous administration of medicine
4.0
20.2
86
238
C03DA01
ATC
spironolactone; oral
3.0
20.2
127
476
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
11.7
20.2
37
33
WX892
NOMESCO Finland
Monitored bed care
3.5
20.1
99
310
N04.9
ICD-10 Finland
Nephrotic syndrome, unspecified
24.2
20.1
28
12
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
15.9
19.9
32
21
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
9.0
19.9
42
49
A10BH05
ATC
linagliptin; oral
4.4
19.8
75
186
R11
ICD-10 Finland
Nausea and vomiting
3.6
19.6
93
282
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
7.8
19.4
45
61
E10.5
ICD-10 Finland
Type 1 diabetes mellitus, With peripheral circulatory complications
47.3
19.3
23
5
C09CA01
ATC
losartan; oral
2.3
19.3
222
1163
N02BE01
ATC
paracetamol; systemic, rectal
2.4
19.2
638
5258
V03AE04
ATC
calcium acetate and magnesium carbonate; systemic
56.5
19.0
22
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.8
19.0
134
539
ZXE20
NOMESCO Finland
More than three and less than five hours
2.6
18.6
152
666
E10.6
ICD-10 Finland
Type 1 diabetes mellitus, With other specified complications
30.9
18.4
24
8
NHQ40
NOMESCO Finland
Amputation of toe
9.2
18.3
38
43
UKC02
NOMESCO Finland
Cystoscopy
2.4
18.3
174
824
A03FA01
ATC
metoclopramide; systemic, rectal
2.4
18.1
179
866
M05BX04
ATC
denosumab; parenteral
4.3
17.9
69
174
C08CA02
ATC
felodipine; oral
2.9
17.9
117
447
T90
ICPC
Diabetes non-insulin dependent
2.3
17.8
206
1078
PBM10
NOMESCO Finland
Closure of arteriovenous fistula of radial artery
68.3
17.8
20
*
JA3FT
NOMESCO Finland
Exchange abdominal catheter with radiological guidance
+∞
17.8
17
*
Z2446
NOMESCO Finland
Social worker
3.7
17.7
81
239
Z99.2
ICD-10 Finland
Dependence on renal dialysis
97.4
17.6
19
*
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
4.6
17.4
62
145
A41.1
ICD-10 Finland
Sepsis due to other specified staphylococcus
21.5
17.4
25
12
25000
ICD-8 Finland
Diabetes mellitus, Sine complicatione
6.3
17.2
46
77
R4190
NOMESCO Finland
Nutritional therapy
5.8
17.2
49
89
E11.5
ICD-10 Finland
Type 2 diabetes mellitus, with peripheral circulatory complications
6.4
17.1
45
74
N18
ICD-10 Finland
Chronic kidney disease
9.8
17.1
34
36
I50.1
ICD-10 Finland
Left ventricular failure
4.1
17.0
69
183
H3601, E113
ICD-10 Finland
NA
7.5
17.0
40
56
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
4.7
16.8
58
131
A06AD11
ATC
lactulose; oral
2.5
16.8
147
665
L03AA13
ATC
pegfilgrastim; parenteral
5.4
16.8
51
100
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
15.5
16.8
27
18
WX204
NOMESCO Finland
Axillary plexus blockaced
5.8
16.8
48
88
A41.8
ICD-10 Finland
Other specified sepsis
8.2
16.7
37
47
UJF30
NOMESCO Finland
Ileoscopy through colon
3.2
16.7
94
325
WX002
NOMESCO Finland
Sedation and analgesia
2.3
16.6
185
948
N08.2*D89.80
ICD-10 Finland
Immunoglobulin A (IgA) nephropathy
23.7
16.5
23
10
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
6.5
16.5
43
70
KH1BT
NOMESCO Finland
Urinary tract cathetrisation with X-ray guidance
11.5
16.4
30
27
E86
ICD-10 Finland
Volume depletion
6.6
16.3
42
67
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
4.1
16.3
65
170
H02AB02
ATC
dexamethasone; systemic
2.9
16.2
104
390
H3603, E113
ICD-10 Finland
NA
12.0
16.2
29
25
SPAT1263
SPAT
Sampling
1.9
16.1
332
2184
WW200
NOMESCO Finland
Immunization
6.1
16.1
44
76
N17.0
ICD-10 Finland
Acute renal failure with tubular necrosis
25.1
16.1
22
9
C08CA13
ATC
lercanidipine; oral
2.6
16.0
131
569
A07AA09
ATC
vancomycin; oral
8.6
15.9
34
41
H25.8
ICD-10 Finland
Other senile cataract
2.6
15.7
127
549
WX882
NOMESCO Finland
High dependency care
5.1
15.7
50
104
EB1CI
NOMESCO Finland
Cone beam imaging of teeth and jaws (3-4 quarters)
26.9
15.7
21
8
G63.2*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic polyneuropathy
26.9
15.7
21
8
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.1
15.6
210
1165
WW400
NOMESCO Finland
Plasmaferesis
163.3
15.5
16
*
R60.0
ICD-10 Finland
Localized oedema
2.7
15.5
111
446
PD4DE
NOMESCO Finland
Lower extremity artery ultrasound examination with Doppler method
7.3
15.5
37
53
R4180
NOMESCO Finland
Podiatric therapy
15.2
15.4
25
17
WX402
NOMESCO Finland
General anaesthesia
2.5
15.4
138
630
R06.0
ICD-10 Finland
Dyspnoea
2.1
15.4
208
1155
RS220
NOMESCO Finland
NA
9.0
15.3
32
37
ZX112
NOMESCO Finland
Subcutaneous
6.0
15.3
42
73
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
10.7
15.3
29
28
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
4.0
15.2
62
165
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
4.5
15.2
54
126
GA4AT
NOMESCO Finland
Cathetrisation of pleural cavity with ultrasound guidance
12.1
15.2
27
23
KAS20
NOMESCO Finland
Allogenic transplantation of kidney from living donor
46.0
15.1
18
*
JA3AT
NOMESCO Finland
Cathetrisation of abdominal cavity with ultrasound guidance
9.7
15.1
30
32
L28
ICPC
Limited function/disability (L)
2.4
15.0
146
696
H36.00
ICD-10 Finland
Diabetic background retinopathy
8.5
14.9
32
39
AA1AD
NOMESCO Finland
CT of head and brain
2.1
14.8
216
1236
I15.9
ICD-10 Finland
Secondary hypertension, unspecified
13.6
14.8
25
19
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.2
14.7
79
264
UJF92
NOMESCO Finland
Capsular endoscopy
8.3
14.7
32
40
D630, C61
ICD-10 Finland
NA
+∞
14.6
14
*
ZX121
NOMESCO Finland
Central venous catheter
81.7
14.6
16
*
A10AD05
ATC
insulin aspart; parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
6.4
14.6
38
62
SPAT1229
SPAT
Assessment of need for aid
3.0
14.6
89
325
ZXA00
NOMESCO Finland
Right side
2.0
14.6
238
1423
177
Kela drug reimbursment
Insulin glargine 300 U / ml
6.8
14.5
36
55
ZXE10
NOMESCO Finland
More than one and less than three hours
1.9
14.4
286
1834
H36.09
ICD-10 Finland
Diabetic retinopathy (E10-E14+ with common fourth character .3)
27.8
14.3
19
7
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.8
14.1
96
373
ZY020
NOMESCO Finland
Telephone, letter or other consultation without direct patient contact
3.4
14.1
70
221
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.0
14.0
223
1316
Q61.3
ICD-10 Finland
Polycystic kidney, unspecified
24.3
13.8
19
8
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
4.1
13.8
54
139
KBV10
NOMESCO Finland
Removal of stent from ureter
13.9
13.8
23
17
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.8
13.8
327
2222
Z01.8
ICD-10 Finland
Other specified special examinations
2.1
13.8
179
969
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
7.8
13.8
31
41
E10
ICD-10 Finland
Type 1 diabetes mellitus
8.6
13.6
29
35
N11.8
ICD-10 Finland
Other chronic tubulo-interstitial nephritis
76.6
13.6
15
*
TK824
NOMESCO Finland
Replacement of peritoneal dialysis catheter extension tube
+∞
13.6
13
*
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
3.0
13.5
79
280
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
4.6
13.5
47
108
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.2
13.5
153
782
A10AE06
ATC
insulin degludec; parenteral
5.0
13.5
43
90
B01AB05
ATC
enoxaparin; parenteral
1.9
13.4
246
1523
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.9
13.4
241
1482
TQW11
NOMESCO Finland
Vacuum treatment of wound
6.5
13.3
34
54
C07AB02
ATC
metoprolol; systemic
2.0
13.3
197
1124
A10BB12
ATC
glimepiride; oral
2.9
13.3
84
311
GD2SN
NOMESCO Finland
Lung ventilation SPECT
14.1
13.3
22
16
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
4.2
13.2
50
125
WX872
NOMESCO Finland
Intensive care
3.4
13.2
64
198
Z96.1
ICD-10 Finland
Presence of intraocular lens
2.3
13.2
130
622
A09AA02
ATC
multienzymes (lipase, protease etc.)
6.4
13.2
34
55
B99
ICD-10 Finland
Other and unspecified infectious diseases
5.9
13.1
36
63
128
Kela drug reimbursment
Cancers of female genital organs
9.6
13.1
26
28
H26.3
ICD-10 Finland
Drug-induced cataract
17.1
13.0
20
12
N03AX16
ATC
pregabalin; oral
2.0
13.0
186
1044
A12AA12
ATC
[U] calcium acetate anhydrous; systemic
28.9
13.0
17
6
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
2.5
12.9
105
452
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
12.9
248
1556
Z3226
NOMESCO Finland
Physiotherapist
2.1
12.9
160
848
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
6.5
12.9
33
53
E11.3
ICD-10 Finland
Type 2 diabetes mellitus, with ophthalmic complications
5.0
12.9
41
86
C09BA02
ATC
enalapril and diuretics; systemic
2.7
12.7
92
371
212
Kela drug reimbursment
Gout
5.5
12.7
37
70
CKC15
NOMESCO Finland
Panretinal photocoagulation
12.6
12.7
22
18
NGQ20
NOMESCO Finland
Amputation of lower leg
15.8
12.7
20
13
T86.1
ICD-10 Finland
Kidney transplant failure and rejection
71.1
12.6
14
*
H28.0*E10.3
ICD-10 Finland
Other specified diabetes mellitus - Diabetic cataract
32.6
12.6
16
5
A28
ICPC
Limited function/disability NOS
2.2
12.5
148
767
BBA40
NOMESCO Finland
Subtotal parathyroidectomy
24.8
12.5
17
7
KBV12
NOMESCO Finland
Transluminal endoscopic removal of stent from ureter
7.1
12.5
30
44
A10BH01
ATC
sitagliptin; oral
2.6
12.5
92
377
PB1AT
NOMESCO Finland
Upper extremity artery PTA
132.1
12.5
13
*
JLE03
NOMESCO Finland
Allogenic total transplantation of pancreas with pancreaticoenterostomy
132.1
12.5
13
*
TKC20
NOMESCO Finland
Catheterisation of bladder
2.8
12.4
83
319
C02CA01
ATC
prazosin; oral
5.5
12.4
36
68
CKC10
NOMESCO Finland
Local photocoagulation of retina
6.1
12.4
33
56
J94.8
ICD-10 Finland
Other specified pleural conditions
6.1
12.4
33
56
ZXA05
NOMESCO Finland
Left side
1.9
12.4
214
1292
CKD40
NOMESCO Finland
Endophotocoagulation of retina
7.6
12.3
28
38
D89.80
ICD-10 Finland
Immunoglobulin A (IgA) deposits in organisms
38.2
12.2
15
*
R31
ICD-10 Finland
Unspecified haematuria
2.4
12.2
107
482
UJF02
NOMESCO Finland
Peroral enteroscopy
16.2
12.2
19
12
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
18.4
12.1
18
10
K65.8
ICD-10 Finland
Other peritonitis
27.2
12.1
16
6
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
3.4
12.1
59
184
EBA15
NOMESCO Finland
Extraction of large number of teeth
4.0
12.1
48
126
PD4BC
NOMESCO Finland
Extensive arterigography of lower extremity with X-ray
6.6
12.0
30
47
M14.6*E10.6
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic neuropathic
47.5
11.9
14
*
C09CA06
ATC
candesartan; oral
2.1
11.8
159
870
GD1UN
NOMESCO Finland
Lung circulation SPECT
15.0
11.8
19
13
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.3
11.8
116
551
GD1AD
NOMESCO Finland
Thorax CT examination
3.7
11.8
51
144
Z51.1
ICD-10 Finland
Chemotherapy session for neoplasm
7.1
11.7
28
41
I15.0
ICD-10 Finland
Renovascular hypertension
16.7
11.7
18
11
TPH05
NOMESCO Finland
Open cannulation of peripheral vein
12.8
11.7
20
16
H05BX02
ATC
paricalcitol; systemic
66.0
11.6
13
*
SPAT1088
SPAT
Blood transfusion
19.3
11.6
17
9
B01AC04
ATC
clopidogrel; oral
2.1
11.6
155
844
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
8.8
11.6
24
28
I35.0
ICD-10 Finland
Aortic (valve) stenosis
3.0
11.6
67
236
N08.5
ICD-10 Finland
Glomerular disorders in systemic connective tissue disorders
121.8
11.5
12
*
SPAT1254
SPAT
Administration of medicine
2.2
11.4
129
656
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.9
11.3
209
1284
WD305
NOMESCO Finland
Simple therapy of methastized malignancy with biomodifiers
10.8
11.3
21
20
QXB99
NOMESCO Finland
Other procedure to treat skin wound, unspecified location
8.2
11.1
24
30
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.8
11.1
72
271
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
6.4
11.0
28
45
A10AD01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
5.6
11.0
31
57
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
6.1
11.0
29
49
RD210
NOMESCO Finland
NA
5.9
11.0
30
53
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.2
11.0
119
591
H3600, E113
ICD-10 Finland
NA
7.0
10.9
26
38
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
7.0
10.9
26
38
N05CF01
ATC
zopiclone; oral
1.8
10.9
254
1685
ZX100
NOMESCO Finland
Oral
8.4
10.9
23
28
J90
ICD-10 Finland
Pleural effusion, not elsewhere classified
3.8
10.9
45
123
WX203
NOMESCO Finland
Infraclavicular plexus blockade
5.3
10.9
32
62
ZX198
NOMESCO Finland
Other local administration
9.0
10.8
22
25
WX610
NOMESCO Finland
Patient controlled analgesia
18.1
10.8
16
9
N04.1
ICD-10 Finland
Nephrotic syndrome, focal and segmental glomerular lesions
28.5
10.8
14
5
N03.1
ICD-10 Finland
Chronic nephritic syndrome, focal and segmental glomerular lesions
28.5
10.8
14
5
I11.0
ICD-10 Finland
Hypertensive heart disease with (congestive) heart failure
4.5
10.7
37
85
I21.49
ICD-10 Finland
Acute subendocardial infarction unspecified coronary artery status
2.8
10.7
70
266
B25.9
ICD-10 Finland
Cytomegaloviral disease, unspecified
21.8
10.7
15
7
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.7
10.7
346
2525
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
3.2
10.7
55
179
C09AA05
ATC
ramipril; oral
1.8
10.7
220
1399
AN1
HP
Coronary angiography
2.2
10.7
119
597
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
4.6
10.6
36
82
TNX92
NOMESCO Finland
Supporting bandage or orthosis of lower limb
6.3
10.5
27
44
C10AA01
ATC
simvastatin; oral
1.7
10.5
357
2638
N03.3
ICD-10 Finland
Chronic nephritic syndrome, diffuse mesangial proliferative glomerulonephritis
+∞
10.4
10
*
N08.5*M31.7
ICD-10 Finland
Glomerular disease states in microscopic polyangiitis
+∞
10.4
10
*
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
10.4
141
773
XX1AT
NOMESCO Finland
Other puncture with ultrasound guidance
9.8
10.3
20
21
KH1YT
NOMESCO Finland
Percutaneous implantation of endoprothesis with radiological guidance
19.1
10.3
15
8
N11.9
ICD-10 Finland
Chronic tubulo-interstitial nephritis, unspecified
19.1
10.3
15
8
E66.00
ICD-10 Finland
Metabolic syndrome
3.2
10.3
53
173
FM1TQ
NOMESCO Finland
Heart perfusion SPECT with low dose CT at rest and with exercise
23.7
10.3
14
6
WX110
NOMESCO Finland
Local anesthesy
1.7
10.2
465
3711
R04.0
ICD-10 Finland
Epistaxis
2.7
10.2
71
281
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.8
10.2
67
256
TPH30
NOMESCO Finland
Insertion of central venous catheter through periferal vein
8.1
10.2
22
28
CKD65
NOMESCO Finland
Pars plana or pars plicata vitrectomy
5.1
10.1
31
63
S92.3
ICD-10 Finland
Fracture of metatarsal bone
4.7
10.1
33
72
ZZA00
NOMESCO Finland
Split skin graft
4.0
10.0
39
101
PB1AE
NOMESCO Finland
Ultrasound examination of arteries of upper extremity
40.6
10.0
12
*
D70.82
ICD-10 Finland
Drug-induced neutropenia
7.8
10.0
22
29
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
3.1
9.9
56
193
E11.4
ICD-10 Finland
Type 2 diabetes mellitus, with neurological complications
4.4
9.9
35
83
QDB99
NOMESCO Finland
Other procedure for wound of skin of lower limb
12.4
9.9
17
14
JN4BD
NOMESCO Finland
Extensive body CT
2.2
9.8
99
476
Z94.4
ICD-10 Finland
Liver transplant status
20.3
9.8
14
7
R53
ICD-10 Finland
Malaise and fatigue
1.9
9.7
155
897
G63.8*N18.8
ICD-10 Finland
Uraemic neuropathy
55.7
9.7
11
*
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
3.1
9.6
51
170
SAA03
NOMESCO Finland
Extended examination of mouth
1.7
9.6
255
1743
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.8
9.6
61
229
NF3AA
NOMESCO Finland
Femur X-ray examination
5.6
9.6
27
50
C01DA14
ATC
isosorbide mononitrate; oral
1.9
9.6
154
895
TQW80
NOMESCO Finland
Local dermatologic skincare
4.6
9.6
32
72
A10AD04
ATC
insulin lispro; parenteral (insulins and analog. for injection, intermediate- or long-acting comb. with fast-acting)
15.3
9.5
15
10
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.6
9.5
68
275
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
3.2
9.5
48
155
N08.2
ICD-10 Finland
Glomerular disorders in blood diseases and disorders involving the immune mechanism
30.4
9.4
12
*
JAL10
NOMESCO Finland
Laparotomy and removal of foreign body
+∞
9.4
9
*
601
Kela drug reimbursment
Severe malabsorption of nutrients, mainly fats
8.2
9.4
20
25
R80
ICD-10 Finland
Isolated proteinuria
8.2
9.4
20
25
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
5.0
9.4
29
60
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.7
9.3
220
1452
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
9.3
306
2218
M01AH05
ATC
etoricoxib; oral
0.6
9.3
208
2931
ZXE00
NOMESCO Finland
One hour or less
1.7
9.2
283
2013
JN1DG
NOMESCO Finland
Very extensive MRI examination of upper part of abdomen with high intensity magnet
6.8
9.2
22
33
TPW99
NOMESCO Finland
Other minor surgical procedure on peripheral vessel or lymphatic system
6.8
9.2
22
33
M86.9
ICD-10 Finland
Osteomyelitis, unspecified
7.9
9.2
20
26
C10AA04
ATC
fluvastatin; oral
2.3
9.2
89
418
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.6
9.1
68
280
JA2AT
NOMESCO Finland
Abdominal puncture with ultrasound guidance
11.6
9.1
16
14
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.9
9.1
56
204
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
4.4
9.1
32
76
C02EA02
ATC
NA
2.9
9.1
56
205
XF602
NOMESCO Finland
Bloodpressure monitoring
9.2
9.1
18
20
TPX15
NOMESCO Finland
Removal of vascular injection port
15.8
9.1
14
9
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
37.2
9.0
11
*
Z94.1
ICD-10 Finland
Heart transplant status
18.9
9.0
13
7
K55.8
ICD-10 Finland
Other vascular disorders of intestine
24.3
8.9
12
5
N39.1
ICD-10 Finland
Persistent proteinuria, unspecified
12.7
8.9
15
12
J04AB02
ATC
rifampicin; systemic
8.1
8.9
19
24
NH1BA
NOMESCO Finland
Ankle extensive X-ray examination
4.7
8.9
29
64
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.2
8.9
88
421
XX3DW
NOMESCO Finland
Time consuming IT work
2.3
8.9
83
386
RS221
NOMESCO Finland
NA
6.4
8.8
22
35
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.8
8.8
164
999
C08CA05
ATC
nifedipine; systemic
2.5
8.8
66
274
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
3.7
8.8
37
104
WF049
NOMESCO Finland
Radiotherapy of metastasis
3.5
8.7
40
120
R33
ICD-10 Finland
Retention of urine
2.3
8.7
80
368
PG1XE
NOMESCO Finland
Other ultrasound examination of blood vessel not elsewhere classified
14.2
8.7
14
10
L01AA01
ATC
cyclophosphamide; systemic
14.2
8.7
14
10
H02AB09
ATC
hydrocortisone; systemic
5.1
8.7
26
52
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.3
8.6
84
398
EBA10
NOMESCO Finland
Surgical removal of tooth
2.3
8.6
81
377
N03.8
ICD-10 Finland
Chronic nephritic syndrome, other
27.9
8.5
11
*
E21.1
ICD-10 Finland
Secondary hyperparathyroidism, not elsewhere classified
27.9
8.5
11
*
D69.5
ICD-10 Finland
Secondary thrombocytopenia
20.3
8.5
12
6
Z00.8
ICD-10 Finland
Other general examinations
2.6
8.5
61
247
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
3.7
8.5
36
102
X59
ICD-10 Finland
Exposure to unspecified factor
1.9
8.4
135
781
ZJX00
NOMESCO Finland
Double balloon technique in gastroenterological endoscopy
91.0
8.4
9
*
N08.5*M31.3
ICD-10 Finland
Glomerular disorders in Wegener's granulomatosis
91.0
8.4
9
*
PC6DE
NOMESCO Finland
NA
91.0
8.4
9
*
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.6
8.4
263
1868
SPAT1164
SPAT
Haemodialysis
+∞
8.3
8
*
E10.01
ICD-10 Finland
Insulin-dependent diabetes diabetic coma with hyperglycemia
+∞
8.3
8
*
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.9
8.3
131
754
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
4.1
8.3
31
78
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
3.8
8.3
34
93
PF1AT
NOMESCO Finland
Intravascular dilatation of arteries of knee, lower leg and ankle (PTA)
8.7
8.3
17
20
A02BC01
ATC
omeprazole; systemic
1.7
8.3
208
1387
ZXM00
NOMESCO Finland
Intraoperative use of ultrasonographic imaging
7.2
8.3
19
27
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
3.3
8.3
41
131
B01AB04
ATC
dalteparin; parenteral
2.9
8.3
49
177
L03AA02
ATC
filgrastim; parenteral
4.2
8.3
30
74
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
7.7
8.2
18
24
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
7.7
8.2
18
24
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.9
8.2
135
791
B03BA03
ATC
hydroxocobalamin; parenteral
2.6
8.2
57
228
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.8
8.1
146
880
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
2.7
8.1
55
215
XX_20
NOMESCO Finland
Bioimpedance measurement
33.7
8.1
10
*
KAC00
NOMESCO Finland
Nephrectomy
17.4
8.1
12
7
KA3EB
NOMESCO Finland
Antegrade pyelography
10.2
8.1
15
15
E11.1
ICD-10 Finland
Type 2 diabetes mellitus, with ketoacidosis
10.2
8.1
15
15
163
Kela drug reimbursment
Abiraterone and enzalutamide
6.0
8.0
21
36
I70.1
ICD-10 Finland
Atherosclerosis of renal artery
22.3
8.0
11
5
J01CF05
ATC
flucloxacillin; systemic
3.5
8.0
36
107
130
Kela drug reimbursment
Malignant tumour
2.2
8.0
80
384
JN2AE
NOMESCO Finland
Ultrasound examination of lower part of abdomen without contrast
7.3
8.0
18
25
CK2X4
NOMESCO Finland
Optical coherence tomography (OCT) of ocular fundus
2.3
8.0
72
328
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
2.2
7.9
83
404
I34.09
ICD-10 Finland
Mitral (valve) insufficiency
3.1
7.9
41
136
QDA10
NOMESCO Finland
Incision of skin of lower limb
13.2
7.9
13
10
M86.6
ICD-10 Finland
Other chronic osteomyelitis
13.2
7.9
13
10
K05.31
ICD-10 Finland
Periodontitis pronounced
2.2
7.9
83
405
I83.0
ICD-10 Finland
Varicose veins of lower extremities with ulcer
4.8
7.9
25
54
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
3.4
7.8
36
109
K07
ICPC
Swollen ankles/oedema
3.1
7.8
41
137
NHQ30
NOMESCO Finland
Amputation of foot, transmetatarsal
10.9
7.8
14
13
OAB73
NOMESCO Finland
Prevention and treatment of malnutrition
10.9
7.8
14
13
E13.9
ICD-10 Finland
Other specified diabetes mellitus, without complications
9.5
7.8
15
16
WX140
NOMESCO Finland
Parabulbar anesthesy
2.9
7.8
45
160
N13.8
ICD-10 Finland
Other obstructive and reflux uropathy
45.5
7.7
9
*
PG5AC
NOMESCO Finland
Contrast examination of injection gate to artery or vein
45.5
7.7
9
*
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.6
7.7
33
95
EB1BA
NOMESCO Finland
Extensive intraoral X-ray examination
25.3
7.6
10
*
TJA33
NOMESCO Finland
Percutaneous introduction of peritoneal dialysis catheter
25.3
7.6
10
*
25008
ICD-8 Finland
Diabetes mellitus, Complicatio alia definita
25.3
7.6
10
*
BEF00
NOMESCO Finland
Continuous subcutaneous glucose monitoring
25.3
7.6
10
*
E11.6
ICD-10 Finland
Type 2 diabetes mellitus, with other specified complications
4.7
7.6
24
52
K31.8
ICD-10 Finland
Other specified diseases of stomach and duodenum
10.2
7.6
14
14
NG4AA
NOMESCO Finland
Lower leg X-ray examination
4.2
7.6
27
66
C79.5
ICD-10 Finland
Secondary malignant neoplasm of bone and bone marrow
3.9
7.5
29
76
116
Kela drug reimbursment
Prostate cancer
2.3
7.5
69
319
E0000UV
ATC
NA
1.6
7.5
260
1885
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.6
7.5
52
208
Z50.1
ICD-10 Finland
Other physical therapy
2.7
7.5
48
183
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
3.4
7.4
34
103
JDA42
NOMESCO Finland
Other endoscopic haemostatic procedure in stomach or pylorus
80.9
7.4
8
*
C03AA03
ATC
hydrochlorothiazide; oral
2.1
7.4
84
423
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.0
7.4
94
499
A04AA02
ATC
granisetron; systemic, transdermal
2.6
7.4
51
203
SPAT1225
SPAT
Implementation of podiatry rehabilitation plan
4.1
7.3
27
68
HA1AA
NOMESCO Finland
X-ray mammography
2.7
7.3
48
186
JN1BG
NOMESCO Finland
MRI examination of upper part of abodmen with high intensity magnet
9.5
7.3
14
15
D638, N185
ICD-10 Finland
NA
+∞
7.3
7
*
N0830, E102
ICD-10 Finland
NA
+∞
7.3
7
*
JL9AE
NOMESCO Finland
Ultrasound examination of pancreas transplant
+∞
7.3
7
*
V03AE05
ATC
sucroferric oxyhydroxide; oral
+∞
7.3
7
*
E102N
ICD-10 Finland
NA
+∞
7.3
7
*
N08.5*M31.0
ICD-10 Finland
Glomerular disorders in Goodpasture's syndrome
+∞
7.3
7
*
C09CA07
ATC
telmisartan; oral
2.4
7.3
62
274
R58
ICD-10 Finland
Haemorrhage, not elsewhere classified
6.3
7.3
18
29
L02BB04
ATC
enzalutamide; oral
6.3
7.3
18
29
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
2.8
7.2
43
157
WX725
NOMESCO Finland
Noninvasive ventilation
2.8
7.2
46
174
2504B
ICD-9 Finland
Diabetes mellitus, Diabetes with renal manifestations[DIABETES MELLITUS CUM COMPLICATIONE OCULI ,TYYPPI I]
30.3
7.2
9
*
L04AA05
ATC
[U] tacrolimus; systemic
30.3
7.2
9
*
I51.1
ICD-10 Finland
Rupture of chordae tendineae, not elsewhere classified
30.3
7.2
9
*
QXA20
NOMESCO Finland
Skin abrasion, unspecified location
20.2
7.1
10
5
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
2.9
7.1
41
145
P01AB01
ATC
metronidazole; oral, rectal
1.6
7.1
244
1758
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
7.1
129
775
K83.0
ICD-10 Finland
Cholangitis
5.7
7.1
19
34
JN3DE
NOMESCO Finland
Abdominal extensive ultrasoudn examination with blood flow measurements after transplantation
12.2
7.1
12
10
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.7
7.1
180
1201
K92.0
ICD-10 Finland
Haematemesis
3.7
7.0
29
81
KAC10
NOMESCO Finland
Total nephrectomy with capsule
7.1
7.0
16
23
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.7
7.0
45
171
B01AA03
ATC
warfarin; systemic
1.7
7.0
179
1195
Z3229
NOMESCO Finland
Other healthcare associate professional
2.1
7.0
75
372
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
5.2
7.0
20
39
TQW99
NOMESCO Finland
Other minor procedure on skin
2.7
7.0
46
179
A40.8
ICD-10 Finland
Other streptococcal sepsis
6.4
7.0
17
27
G72.8
ICD-10 Finland
Other specified myopathies
5.5
6.9
19
35
H26.2
ICD-10 Finland
Complicated cataract
5.9
6.9
18
31
Z46.8
ICD-10 Finland
Fitting and adjustment of other specified devices
3.7
6.9
28
77
N13.9
ICD-10 Finland
Obstructive and reflux uropathy, unspecified
13.9
6.9
11
8
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.8
6.9
130
792
M10
ICD-10 Finland
Gout
2.7
6.8
44
168
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.5
6.8
51
212
JAH00
NOMESCO Finland
Laparotomy
3.4
6.8
31
94
NF1AA
NOMESCO Finland
Hip X-ray examination
2.1
6.8
72
355
M01AE01
ATC
ibuprofen; systemic, rectal
0.7
6.8
461
5315
PWE00
NOMESCO Finland
Reoperation for deep haemorrhage in surgery of peripheral vessels and lymphatic system
11.1
6.8
12
11
E87.2
ICD-10 Finland
Acidosis
11.1
6.8
12
11
ZXA10
NOMESCO Finland
Bilateral
1.7
6.8
147
935
A49.8
ICD-10 Finland
Other bacterial infections of unspecified site
9.4
6.8
13
14
TNX33
NOMESCO Finland
Custom moulded cast, unspecified region
2.9
6.8
39
138
25002
ICD-8 Finland
Diabetes mellitus, Retinopathia diabetica
40.4
6.8
8
*
PBM09
NOMESCO Finland
Closure of arteriovenous fistula of brachial artery
40.4
6.8
8
*
N18.4
ICD-10 Finland
Chronic kidney disease, stage 4
16.9
6.8
10
6
RJ410
NOMESCO Finland
NA
16.9
6.8
10
6
L02.9
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle, unspecified
4.2
6.7
24
59
WD205
NOMESCO Finland
Therapy of methastized malignancy with hormones
7.3
6.7
15
21
A10BA02
ATC
metformin; oral
1.6
6.7
207
1450
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
4.3
6.7
23
55
H26.02
ICD-10 Finland
Presenil cataract
3.7
6.6
27
75
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.4
6.6
53
229
I85.9
ICD-10 Finland
Oesophageal varices without bleeding
12.4
6.6
11
9
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
3.5
6.6
29
86
I21.41
ICD-10 Finland
Acute subendocardial infarction stenosed coronary artery
2.5
6.6
49
203
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.2
6.5
61
285
C78.6
ICD-10 Finland
Secondary malignant neoplasm of retroperitoneum and peritoneum
6.9
6.5
15
22
KBV02
NOMESCO Finland
Cystoscopic insertion of stent into ureter
3.9
6.5
25
66
CKD70
NOMESCO Finland
Excision of preretinal or epiretinal membrane
5.1
6.5
19
38
TFC00
NOMESCO Finland
Catheterisation of right atrium or ventricle
5.1
6.5
19
38
L89
ICD-10 Finland
Decubitus ulcer and pressure area
4.6
6.5
21
47
I35.2
ICD-10 Finland
Aortic (valve) stenosis with insufficiency
3.3
6.5
31
98
S91.3
ICD-10 Finland
Open wound of other parts of foot
3.6
6.4
27
77
I79.2*E10.5
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic peripheral angiopathy
70.4
6.4
7
*
M86.4
ICD-10 Finland
Chronic osteomyelitis with draining sinus
70.4
6.4
7
*
TK823
NOMESCO Finland
Peritoneal permeability analysis
70.4
6.4
7
*
PWG00
NOMESCO Finland
Reoperation on peripheral vessels for thrombosis or embolism
70.4
6.4
7
*
KAB00
NOMESCO Finland
Biopsy of kidney or pelvis of kidney
70.4
6.4
7
*
H3603, E107
ICD-10 Finland
NA
70.4
6.4
7
*
B81
ICPC
Anaemia vit B12/folate deficiency
2.8
6.4
39
145
FPE00
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with ventricular electrode
3.8
6.4
25
67
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.4
6.4
51
218
R60.9
ICD-10 Finland
Oedema, unspecified
2.7
6.4
42
163
PD4AC
NOMESCO Finland
Arterigography of lower extremity with X-ray
5.0
6.4
19
39
WX100
NOMESCO Finland
Conjunctival surface anesthesia
1.9
6.4
96
542
A79
ICPC
Malignancy NOS
5.2
6.3
18
35
C03EB01
ATC
furosemide and potassium-sparing agents; systemic
2.7
6.3
41
157
D50.8
ICD-10 Finland
Other iron deficiency anaemias
6.0
6.3
16
27
N28.9
ICD-10 Finland
Disorder of kidney and ureter, unspecified
11.1
6.3
11
10
XG410
NOMESCO Finland
Flow-volume spirometry
2.8
6.3
38
141
JN3DG
NOMESCO Finland
Very extensive MRI examination with high intensity magnet
18.2
6.3
9
5
QXB10
NOMESCO Finland
Exchange of dressing for large skin wound, unspecified location
18.2
6.3
9
5
2507B
ICD-9 Finland
Diabetes mellitus, Diabetes with peripheral circulatory disorders[DIABETES MELLITUS CUM COMPLICAT ALIA ,TYYPPI I]
18.2
6.3
9
5
Y83.2
ICD-10 Finland
Surgical operation with anastomosis, bypass or graft as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
18.2
6.3
9
5
ZYB02
NOMESCO Finland
Outreach service at unit of another specialty
18.2
6.3
9
5
KA1MN
NOMESCO Finland
Glomerular filtration rate (GFR) Isotope mesurement
18.2
6.3
9
5
2501B
ICD-9 Finland
Diabetes mellitus, Diabetes with ketoacidosis[DIABETES MELLITUS CUM KETOACIDOSI ,TYYPPI I]
18.2
6.3
9
5
G99.0*E10.4
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic autonomic neuropathy
+∞
6.3
6
*
E112N
ICD-10 Finland
NA
+∞
6.3
6
*
PBU99
NOMESCO Finland
Other repair after previous reconstruction of arteries of upper extremity
+∞
6.3
6
*
K76.6
ICD-10 Finland
Portal hypertension
+∞
6.3
6
*
M31.0
ICD-10 Finland
Hypersensitivity angiitis
+∞
6.3
6
*
Z49
ICD-10 Finland
Care involving dialysis
+∞
6.3
6
*
M31.7
ICD-10 Finland
Microscopic polyangiitis
+∞
6.3
6
*
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
2.3
6.2
54
244
7151
FHL
Kidney transplantation
26.9
6.2
8
*
NH3BG
NOMESCO Finland
MRI of foot
26.9
6.2
8
*
KA9AE
NOMESCO Finland
Ultrasound examination transplanted kidney
26.9
6.2
8
*
C64.88
ICD-10 Finland
Other malignant neoplasm of kidney, except renal pelvis
4.0
6.2
23
59
IAZ97
NOMESCO Finland
Psychiatric consultation in another specialty
5.8
6.2
16
28
A06AH03
ATC
naloxegol; oral
5.8
6.2
16
28
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.7
6.2
118
723
I70.9
ICD-10 Finland
Generalized and unspecified atherosclerosis
3.6
6.2
26
75
K90.3
ICD-10 Finland
Pancreatic steatorrhoea
7.8
6.1
13
17
C56.71
ICD-10 Finland
Serous epithelial malignant tumor of the ovary
7.8
6.1
13
17
FN2BA
NOMESCO Finland
Percutaneous transluminal coronary angioplasty with stent (includes balloon pre-dilation)
2.3
6.1
53
240
L02BB03
ATC
bicalutamide; oral
2.8
6.1
37
138
SPAT1301
SPAT
No procedures
1.5
6.1
224
1629
PF1BT
NOMESCO Finland
Extensive PTA of arteries of knee, lower leg and ankle
8.7
6.1
12
14
XLD00
NOMESCO Finland
Sytologyspecimen from mouth of uterus
2.2
6.1
57
267
RJ411
NOMESCO Finland
NA
10.1
6.0
11
11
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
10.1
6.0
11
11
JL5BG
NOMESCO Finland
MRI examinaiton of bile and pancreas ducts with high intesity magnet
4.2
6.0
21
51
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.2
6.0
57
268
XKD00
NOMESCO Finland
Uroflowmetry
1.7
6.0
144
940
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.0
6.0
78
416
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
2.8
6.0
36
133

Mortality – FinRegistry

Association

Association between endpoint D3_ANAEMIAINCHRONICDISEASE and mortality.

Females

Parameter HR [95% CI] p-value
D3_ANAEMIAINCHRONICDISEASE 5.038 [3.9, 6.51] < 0.001
Birth year 0.999 [0.99, 1.01] 0.886

During the follow-up period (1.1.1998 — 31.12.2019), 1200 out of 1901 females with D3_ANAEMIAINCHRONICDISEASE died.

Males

Parameter HR [95% CI] p-value
D3_ANAEMIAINCHRONICDISEASE 5.365 [3.81, 7.55] < 0.001
Birth year 0.989 [0.98, 1.0] 0.029

During the follow-up period (1.1.1998 — 31.12.2019), 1351 out of 2167 males with D3_ANAEMIAINCHRONICDISEASE died.

Mortality risk

Mortality risk for people of age

years, who have D3_ANAEMIAINCHRONICDISEASE.

N-year risk Females Males
1 0.614% 1.111%
5 3.131% 6.608%
10 7.479% 15.419%
15 15.405% 27.787%
20 25.086% 42.426%

Relationships between endpoints

Index endpoint: D3_ANAEMIAINCHRONICDISEASE – Anaemia in chronic diseases classified elsewhere

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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