Polycystic ovarian syndrome

E4_PCOS

No definition available.

Endpoint definition

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FinnGen phenotype data

414262 individuals

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Apply sex-specific rule

Sex only females

230709

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Check conditions None

230709

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 E28.2

Hospital discharge: ICD-9 2564

Hospital discharge: ICD-8 25690

Cause of death: ICD-10 E28.2

Cause of death: ICD-9 2564

Cause of death: ICD-8 25690

2 out of 7 registries used, show all original rules.

1575

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Check minimum number of events None

1575

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Include endpoints None

1575

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Remove individuals based on genotype QC

1424

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E4_PCOS

Control definitions

Control exclude E4_ENDOGLAND

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF6

Parent code in ICD-10 E28

Name in latin Morbus polycysticus ovariorum

NAME	E4_PCOS
CONTROL_EXCLUDE	E4_ENDOGLAND
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX	2
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	E282
HD_ICD_9	2564
HD_ICD_8	25690
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	E282
COD_ICD_9	2564
COD_ICD_8	25690
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Polycystic ovarian syndrome based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1424	1424	-
Unadjusted prevalence (%)	0.38	0.68	-
Mean age at first event (years)	28.50	28.50	-

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.07	4.09 [0.96, 17.39]	5.6e-2	10
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_PCOS – Polycystic ovarian syndrome
GWS hits: 8

Survival analyses between endpoints

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Plot

before Polycystic ovarian syndrome
after Polycystic ovarian syndrome

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Table

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Drugs most likely to be purchased after Polycystic ovarian syndrome

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