Specific development disorders of speech and language

F5_SPEECH

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 F80
  • Hospital discharge: ICD-9 3153
  • Hospital discharge: ICD-8 3060
  • Cause of death: ICD-10 F80
  • Cause of death: ICD-9 3153
  • Cause of death: ICD-8 3060

2 out of 7 registries used, show all original rules.

2528

4. Check minimum number of events

None

2528

5. Include endpoints

2528

6. Filter based on genotype QC (FinnGen only)

2528

Control definitions (FinnGen only)

Control exclude
F5_PSYCHDEV

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9
Parent code in ICD-10
F80-F89
Name in latin
Perturbationes specificae progressus dictionis et linguae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 65508 19893 45590
Only index persons 49393 15358 34035
Unadjusted period prevalence (%)
Whole population 1.06 0.57 1.27
Only index persons 1.07 0.56 1.30
Median age at first event (years)
Whole population 5.39 5.72 5.22
Only index persons 5.75 6.18 5.55

-FinnGen-

Key figures

All Female Male
Number of individuals 2528 1177 1351
Unadjusted period prevalence (%) 0.51 0.40 0.60
Median age at first event (years) 7.36 8.89 6.03

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
2144
Matched controls
21042
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
F80.1
ICD-10 Finland
Expressive language disorder
4609.8
323.0
1075
*
F80.2
ICD-10 Finland
Receptive language disorder
1413.8
323.0
455
*
F80.9
ICD-10 Finland
Developmental disorder of speech and language, unspecified
882.9
320.3
309
*
F80.0
ICD-10 Finland
Specific speech articulation disorder
106.5
267.0
291
31
3153A
ICD-9 Finland
Specific delays in development, Developmental speech or language disorder[KIELENKEHITYKSEN ERITYISVAIKEUS]
+∞
223.5
212
*
F83
ICD-10 Finland
Mixed specific developmental disorders
735.0
208.8
204
*
F80.8
ICD-10 Finland
Other developmental disorders of speech and language
327.5
180.8
182
6
F82
ICD-10 Finland
Specific developmental disorder of motor function
289.1
160.8
163
6
3153X
ICD-9 Finland
Specific delays in development, Developmental speech or language disorder[PUHEEN KEHITYKSEN ERITYISVAIKEUS]
+∞
143.4
137
*
R62.0
ICD-10 Finland
Delayed milestone
18.9
115.1
181
102
F81.0
ICD-10 Finland
Specific reading disorder
63.7
95.0
111
18
XA800
NOMESCO Finland
Neuropsychological investigation
7.5
89.5
223
319
Z2445
NOMESCO Finland
Psychologist
4.9
83.1
298
673
F81.3
ICD-10 Finland
Mixed disorder of scholastic skills
287.2
82.6
84
*
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
13.6
74.1
132
101
AA1AD
NOMESCO Finland
CT of head and brain
3.1
72.7
474
1770
Z3226
NOMESCO Finland
Physiotherapist
2.9
69.5
509
2046
Z2446
NOMESCO Finland
Social worker
3.6
66.5
330
999
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.5
66.2
255
614
F70.0
ICD-10 Finland
Mild mental retardation, With the statement of no, or minimal, impairment of behaviour
43.4
65.0
81
19
Z50.5
ICD-10 Finland
Speech therapy
8.8
64.8
144
170
R4130
NOMESCO Finland
Speech therapy
10.8
64.5
128
123
Z01.1
ICD-10 Finland
Examination of ears and hearing
3.1
63.6
401
1451
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
5.6
55.0
168
312
Z2221
NOMESCO Finland
Medical doctor
2.3
51.3
612
3141
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
4.3
49.9
200
496
F81.9
ICD-10 Finland
Developmental disorder of scholastic skills, unspecified
38.5
47.9
61
16
R1260
NOMESCO Finland
Evaluation of communicative skills
11.8
47.8
90
78
F84.5
ICD-10 Finland
Asperger syndrome
30.3
46.8
63
21
F84.9
ICD-10 Finland
Pervasive developmental disorder, unspecified
125.5
46.6
50
*
N03AG01
ATC
valproic acid; systemic, rectal
3.9
46.1
201
538
Z3231
NOMESCO Finland
Registered nurse
2.1
44.5
663
3715
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.4
43.8
419
1908
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.2
43.2
249
831
R47.0
ICD-10 Finland
Dysphasia and aphasia
24.2
42.0
60
25
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
4.1
41.7
172
437
F81.8
ICD-10 Finland
Other developmental disorders of scholastic skills
54.6
41.2
49
9
N05AX08
ATC
risperidone; systemic
3.2
40.8
229
749
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
7.9
40.6
95
122
ZXE11
NOMESCO Finland
Procedure duration 60 to 89 minutes
2.9
39.5
268
994
ZY010
NOMESCO Finland
Hospital outpatient
3.1
39.3
236
807
R4110
NOMESCO Finland
Physiotherapy
2.1
39.2
518
2734
R4120
NOMESCO Finland
Occupational therapy
3.9
38.5
170
459
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
3.1
37.9
232
805
N05AH03
ATC
olanzapine; systemic
3.2
37.9
215
708
R47.8
ICD-10 Finland
Other and unspecified speech disturbances
15.1
37.6
63
42
F90.0
ICD-10 Finland
Disturbance of activity and attention
3.3
37.1
202
645
G40.9
ICD-10 Finland
Epilepsy, unspecified
5.0
36.9
123
252
F80
ICD-10 Finland
Specific developmental disorders of speech and language
356.5
35.8
36
*
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.1
35.5
210
709
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.9
35.1
225
805
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.8
34.5
240
901
3159X
ICD-9 Finland
Specific delays in development, Unspecified delay in development
+∞
34.2
33
*
N05AH04
ATC
quetiapine; oral
2.2
33.9
423
2157
N03AF02
ATC
oxcarbazepine; oral
4.5
33.3
122
276
R56.8
ICD-10 Finland
Other and unspecified convulsions
3.1
33.0
194
653
30600
ICD-8 Finland
Special symptoms not elsewhere classified, Stammering and stuttering
+∞
32.1
31
*
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
4.3
32.1
123
291
F84.0
ICD-10 Finland
Childhood autism
+∞
31.1
30
*
N05AX12
ATC
aripiprazole; systemic
3.2
31.1
174
564
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
8.1
30.9
71
89
F70.1
ICD-10 Finland
Mild mental retardation, Significant impairment of behaviour requiring attention or treatment
42.1
30.6
38
9
F81.1
ICD-10 Finland
Specific spelling disorder
84.8
30.6
34
*
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
3.5
30.3
152
455
XF400
NOMESCO Finland
ECG with 12 standard connections
2.2
30.3
335
1612
F84.8
ICD-10 Finland
Other pervasive developmental disorders
+∞
30.1
29
*
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.6
29.9
230
916
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.4
29.6
274
1206
N03AX14
ATC
levetiracetam; systemic
4.8
28.2
96
202
F29
ICD-10 Finland
Unspecified nonorganic psychosis
3.0
28.1
170
581
ZXD10
NOMESCO Finland
Scheduled procedure
1.8
27.8
672
4330
RL140
NOMESCO Finland
NA
16.1
27.8
45
28
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.9
27.5
180
648
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
27.3
608
3809
ICZ03
NOMESCO Finland
Participation in compiling a psychiatric treatment plan
3.2
27.3
154
503
R4160
NOMESCO Finland
Other therapy enhancing rehabilitation
3.8
26.9
120
327
78159
ICD-8 Finland
Other symptoms referable to nervous system and special senses, Laesio loquendi alia sive NUD
269.3
26.6
27
*
Z3229
NOMESCO Finland
Other healthcare associate professional
2.5
26.5
217
894
ZXE13
NOMESCO Finland
Procedure duration 90 to 119 minutes
2.9
26.3
166
585
R47.1
ICD-10 Finland
Dysarthria and anarthria
14.7
26.2
44
30
ZXE05
NOMESCO Finland
Procedure duration 40 to 49 minutes
2.9
26.0
164
577
B01AC04
ATC
clopidogrel; oral
2.8
25.8
176
652
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.6
25.2
196
782
A28
ICPC
Limited function/disability NOS
2.5
25.2
218
926
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.9
24.6
403
2261
ZXE20
NOMESCO Finland
More than three and less than five hours
2.3
24.6
254
1176
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
24.2
646
4252
IGY01
NOMESCO Finland
Accelerated psychiatric treatment contact
3.9
24.0
102
267
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
4.1
23.6
95
237
ZXE15
NOMESCO Finland
Procedure duration 120 to 149 minutes
3.8
23.4
102
273
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
2.5
23.2
197
827
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.1
23.1
296
1507
RT150
NOMESCO Finland
NA
10.0
23.0
46
46
RL130
NOMESCO Finland
NA
13.3
23.0
40
30
TPH04
NOMESCO Finland
Cathetrisation of vein
1.9
22.9
355
1946
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
22.8
375
2101
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
3.1
22.7
130
429
F88
ICD-10 Finland
Other disorders of psychological development
82.8
22.5
25
*
EBA15
NOMESCO Finland
Extraction of large number of teeth
4.1
22.1
89
222
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
4.5
22.1
79
176
N06BA04
ATC
methylphenidate; oral
3.0
21.9
135
466
IBZ01
NOMESCO Finland
Profession-specific psychiatric evaluation
3.7
21.5
96
262
G80.2
ICD-10 Finland
Spastic hemiplegic cerebral palsy
26.2
21.1
29
11
ZXE00
NOMESCO Finland
One hour or less
1.6
21.0
731
5126
ZXE02
NOMESCO Finland
Procedure duration 10 to 19 minutes
2.8
21.0
139
505
WX892
NOMESCO Finland
Monitored bed care
2.6
20.9
160
632
ZXE03
NOMESCO Finland
Procedure duration 20 to 29 minutes
2.6
20.8
157
616
P24
ICPC
Specific learning problem
4.9
20.8
69
142
N05BA01
ATC
diazepam; systemic, rectal
2.2
20.5
224
1062
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
4.2
20.4
78
186
N03AX09
ATC
lamotrigine; oral
2.8
20.4
136
497
N19
ICPC
Speech disorder
4.2
20.2
78
188
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
7.1
20.0
49
69
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
5.1
19.1
60
117
R41.0
ICD-10 Finland
Disorientation, unspecified
4.9
19.0
62
126
R42
ICD-10 Finland
Dizziness and giddiness
1.9
18.9
311
1734
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.7
18.8
135
517
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.8
18.7
332
1903
R55
ICD-10 Finland
Syncope and collapse
2.3
18.5
180
808
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
7.0
18.3
45
64
G80.1
ICD-10 Finland
Spastic diplegic cerebral palsy
14.9
18.2
30
20
7819X
ICD-9 Finland
Symptoms involving nervous and musculoskeletal systems, Other symptoms involving nervous and musculoskeletal systems[SYMPTOMATA ALIA SYSTEMATIS NERVORUM ET MUSCULOSCEL]
8.5
17.9
39
46
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
2.1
17.9
225
1130
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.9
17.9
292
1623
F80.3
ICD-10 Finland
Acquired aphasia with epilepsy [Landau-Kleffner]
+∞
17.6
17
*
183
Kela drug reimbursment
Lamotrigin and topiramate
5.9
17.6
49
83
N05CD08
ATC
midazolam; nasal, systemic
4.5
17.5
63
142
N05AH02
ATC
clozapine; systemic
3.8
17.5
74
194
P99
ICPC
Psychological disorders other
3.3
17.4
90
278
WX408
NOMESCO Finland
General anesthesy, balanced
1.6
17.3
500
3308
IGY99
NOMESCO Finland
Other psychiatric treatment contact
3.0
17.3
104
355
L17
ICPC
Foot/toe symptom/complaint
1.6
17.3
481
3154
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.8
17.2
324
1893
ZXY51
NOMESCO Finland
2-person team, doctor-nurse
3.5
17.1
80
229
WX882
NOMESCO Finland
High dependency care
2.8
17.0
114
419
N06AB04
ATC
citalopram; systemic
1.8
17.0
293
1659
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
4.6
16.9
59
129
P22
ICPC
Child behaviour symptom/complaint
3.9
16.8
69
177
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
2.6
16.5
122
476
F70.9
ICD-10 Finland
Mild mental retardation, Without mention of impairment of behaviour
27.2
16.3
22
8
L28
ICPC
Limited function/disability (L)
2.0
16.3
210
1067
ICB02
NOMESCO Finland
Psychiatric treatment plan, extended/prolonged
4.9
16.3
53
108
F20.9
ICD-10 Finland
Schizophrenia, unspecified
4.0
16.1
65
164
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.7
16.0
341
2065
N05BA09
ATC
clobazam; oral
6.1
16.0
43
70
C10AA05
ATC
atorvastatin; oral
1.7
15.9
337
2036
4212
FHL
Maxillapremmaxilla opening septum resection and reconstruction
24.2
15.8
22
9
SPAT1365
SPAT
Health check-up performed during first study year due to special need in students of upper secondary schools or vocational schools
5.5
15.7
46
83
IGY02
NOMESCO Finland
Psychiatric monitoring contact
2.8
15.7
102
368
N05BA06
ATC
lorazepam; systemic, sublingual
3.1
15.7
87
283
F89
ICD-10 Finland
Unspecified disorder of psychological development
59.3
15.6
18
*
ZXE17
NOMESCO Finland
Procedure duration 150 to 179 minutes
4.4
15.6
57
131
3150A
ICD-9 Finland
Specific delays in development, Specific reading disorder
+∞
15.5
15
*
R5599
NOMESCO Finland
Other rehabilitation service
3.6
15.5
71
200
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.8
15.5
301
1773
R1250
NOMESCO Finland
Evaluation of functional capability
4.4
15.4
55
124
N05AD01
ATC
haloperidol; systemic
4.0
15.3
62
157
NK6MA
NOMESCO Finland
Measurement of bone age from hand and elbow using X-ray
2.9
15.3
94
327
IGV01
NOMESCO Finland
Psychiatric network contact
4.4
15.3
55
125
SPAT1224
SPAT
Implementation of speech therapy rehabilitation plan
4.2
15.2
58
139
R1410
NOMESCO Finland
Drawing up a rehabilitation plan
12.2
15.2
27
22
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
5.1
15.0
47
92
ZYC01
NOMESCO Finland
Remote contact by phone
2.4
15.0
127
532
F98.8
ICD-10 Finland
Other specified behavioural and emotional disorders with onset usually occurring in childhood and adolescence
6.4
15.0
39
61
K03.66
ICD-10 Finland
Tooth plaque
2.0
14.9
201
1036
R51.80
ICD-10 Finland
Headache
1.7
14.7
326
1992
3141A
ICD-9 Finland
Hyperkinetic syndrome of childhood, Hyperkinesis with developmental delay
56.0
14.7
17
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
2.2
14.6
148
678
XX4AW
NOMESCO Finland
NA
6.5
14.4
37
57
N06AX11
ATC
mirtazapine; oral
1.6
14.3
469
3184
Z13.4
ICD-10 Finland
Special screening examination for certain developmental disorders in childhood
35.6
14.3
18
5
ICC04
NOMESCO Finland
Psychiatric treatment plan, permanent discontinuation
3.0
14.2
83
280
N05AA02
ATC
levomepromazine; systemic
3.3
14.1
72
221
IEV99
NOMESCO Finland
Other psychiatric network intervention
5.2
14.1
43
82
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
3.1
14.1
76
243
ZXA10
NOMESCO Finland
Bilateral
1.7
14.1
306
1860
RT420
NOMESCO Finland
NA
14.2
13.9
23
16
F90.9
ICD-10 Finland
Hyperkinetic disorder, unspecified
5.9
13.8
38
64
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
4.0
13.7
54
134
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.5
13.7
664
4916
R1210
NOMESCO Finland
Medical assessment of need and possibilities to rehabilitation
4.6
13.6
46
99
PA7CD
NOMESCO Finland
CT angiography of neck and brain, extensive
9.0
13.5
28
31
WX110
NOMESCO Finland
Local anesthesy
1.4
13.4
1423
12201
Q93.5
ICD-10 Finland
Other deletions of part of a chromosome
138.2
13.4
14
*
SPAT1297
SPAT
Other function in accordance with speech therapy nomenclature
6.1
13.1
35
57
C08CA01
ATC
amlodipine; oral
1.7
13.1
317
1984
TPH07
NOMESCO Finland
Cathetrisation of artery
2.1
13.1
154
753
H66.0
ICD-10 Finland
Acute suppurative otitis media
1.7
13.1
315
1969
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
6.1
12.8
34
55
RT160
NOMESCO Finland
NA
7.9
12.6
28
35
IAA01
NOMESCO Finland
Assessment of need for psychiatric treatment
2.5
12.5
99
400
A06AD11
ATC
lactulose; oral
1.9
12.5
186
997
3154A
ICD-9 Finland
Specific delays in development, Coördination disorder
+∞
12.4
12
*
DFF20
NOMESCO Finland
Audiometry for children
6.4
12.4
32
50
RS220
NOMESCO Finland
NA
3.8
12.4
51
133
H01AC01
ATC
somatropin; parenteral
4.2
12.3
46
110
M79.6
ICD-10 Finland
Pain in limb
1.5
12.2
528
3800
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.0
12.2
156
790
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.3
12.1
114
503
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.2
12.1
129
605
P07.2
ICD-10 Finland
Extreme immaturity
37.1
12.1
15
*
R13
ICD-10 Finland
Dysphagia
2.6
12.0
87
336
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
2.9
12.0
71
243
WX002
NOMESCO Finland
Sedation and analgesia
1.7
12.0
258
1562
SPAT1396
SPAT
Meeting with multidisciplinary group of experts
3.6
12.0
53
147
R5120
NOMESCO Finland
Preparation of an aid
4.3
11.9
43
99
S18
ICPC
Laceration/cut
1.4
11.9
644
4840
K04.5
ICD-10 Finland
Chronic apical periodontitis
1.6
11.9
307
1954
RS140
NOMESCO Finland
NA
6.9
11.9
29
42
P29
ICPC
Psychological sympt/compl other
1.9
11.8
177
953
F79.0
ICD-10 Finland
Unspecified mental retardation, with the statement of no, or minimal, impairment of behaviour
6.2
11.8
31
50
PA7BD
NOMESCO Finland
CT angiography of neck and brain
5.9
11.7
32
54
P85
ICPC
Mental retardation
7.4
11.7
27
36
504
Kela drug reimbursment
Conditions requiring daily forced enteral nutrition
4.0
11.7
46
115
H81
ICPC
Excessive ear wax
1.8
11.7
210
1202
IEP99
NOMESCO Finland
Other psychiatric family intervention
4.6
11.6
39
84
N05AN01
ATC
lithium; oral
3.4
11.6
56
167
RT490
NOMESCO Finland
NA
16.2
11.5
18
11
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.0
11.5
143
717
N05BA04
ATC
oxazepam; oral
1.6
11.5
355
2362
Z71.8
ICD-10 Finland
Other specified counselling
1.5
11.4
492
3531
H53.0
ICD-10 Finland
Amblyopia ex anopsia
3.6
11.4
50
138
3152A
ICD-9 Finland
Specific delays in development, Other specific learning difficulties
+∞
11.4
11
*
F20.30
ICD-10 Finland
Undifferentiated schizophrenia continuous
3.8
11.3
47
124
H50.31
ICD-10 Finland
Intermittent exotropia
3.6
11.3
50
139
N17
ICPC
Vertigo/dizziness
1.8
11.3
184
1021
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.0
11.3
155
807
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.5
11.2
539
3955
K02.1
ICD-10 Finland
Caries of dentine
1.4
11.1
1219
10329
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
3.3
11.1
56
172
RS222
NOMESCO Finland
NA
4.2
11.1
41
97
DCA20
NOMESCO Finland
Insertion of ventilating tube through tympanic membrane
1.8
11.1
184
1024
ZXD05
NOMESCO Finland
Urgent procedure
1.5
11.1
500
3616
7834D
ICD-9 Finland
Symptoms concerning nutrition, metabolism and development, Lack of expected normal physiological development[LAPSEN NORMAALIN KEHITTYMISEN HIDASTUMINEN]
24.7
11.0
15
6
C03CA01
ATC
furosemide; systemic
1.7
10.9
262
1632
N03AX11
ATC
topiramate; oral
3.2
10.9
55
170
ZYB04
NOMESCO Finland
Outreach service in patient’s home or everyday environment
5.7
10.8
30
52
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
2.9
10.8
67
235
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
3.6
10.8
48
134
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
10.6
471
3392
F94.8
ICD-10 Finland
Other childhood disorders of social functioning
17.6
10.6
16
9
G40.10
ICD-10 Finland
Simple partial seizures
4.8
10.6
34
70
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.4
10.6
88
368
F94.9
ICD-10 Finland
Childhood disorder of social functioning, unspecified
21.2
10.6
15
7
Z87.6
ICD-10 Finland
Personal history of certain conditions arising in the perinatal period
3.2
10.6
53
163
TKC20
NOMESCO Finland
Catheterisation of bladder
2.3
10.6
96
420
K90
ICPC
Stroke/cerebrovascular accident
4.2
10.5
39
93
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
4.1
10.5
40
98
N05AB03
ATC
perphenazine; systemic, rectal
3.0
10.5
60
201
F05.9
ICD-10 Finland
Delirium, unspecified
4.5
10.5
36
80
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
1.9
10.4
164
900
H52.2
ICD-10 Finland
Astigmatism
3.0
10.4
57
187
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
5.2
10.4
31
59
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.2
10.4
107
495
IFA01
NOMESCO Finland
Psychiatric pharmacotherapy plan, not specified
3.0
10.4
59
196
3140B
ICD-9 Finland
Hyperkinetic syndrome of childhood, Attention deficit disorder
108.5
10.3
11
*
ICB03
NOMESCO Finland
Psychiatric treatment plan, monitoring
2.9
10.3
61
210
ZXA05
NOMESCO Finland
Left side
1.6
10.3
308
2032
SPAT1216
SPAT
Assessment of functional ability
1.7
10.3
198
1157
IFA99
NOMESCO Finland
Other psychiatric pharmacotherapy service
4.5
10.3
35
77
XF600
NOMESCO Finland
Bloodpressure measurement
1.9
10.1
142
746
K05.10
ICD-10 Finland
Gingivitis (chronic) NOS
1.6
10.1
281
1821
K59.09
ICD-10 Finland
Constipation, unspecified
2.2
10.1
100
455
TAB00
NOMESCO Finland
Lumbar puncture
2.3
10.1
88
379
N03AE01
ATC
clonazepam; systemic
2.4
10.1
84
352
N18
ICPC
Paralysis/weakness
4.8
10.0
32
66
SPAT1307
SPAT
Psychosocial counselling and guidance
1.6
10.0
248
1560
A02BC02
ATC
pantoprazole; systemic
1.4
9.9
816
6558
H53.1
ICD-10 Finland
Subjective visual disturbances
2.2
9.9
95
428
V628A
ICD-9 Finland
Other psychosocial circumstances, Other psychological or physical stress, not elsewhere classified
39.4
9.9
12
*
F70
ICD-10 Finland
Mild mental retardation
39.4
9.9
12
*
Z63.7
ICD-10 Finland
Other stressful life events affecting family and household
2.5
9.9
74
294
H66.9
ICD-10 Finland
Otitis media, unspecified
1.6
9.8
251
1589
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
2.5
9.8
73
288
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
3.6
9.8
43
120
XA820
NOMESCO Finland
NA
8.0
9.7
21
26
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.4
9.7
659
5131
F21
ICD-10 Finland
Schizotypal disorder
6.9
9.6
23
33
R5140
NOMESCO Finland
Monitoring the use of the aid
2.1
9.6
111
540
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.5
9.6
357
2473
N30.0
ICD-10 Finland
Acute cystitis
1.6
9.6
227
1409
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
2.9
9.6
57
198
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.4
9.6
76
312
3199A
ICD-9 Finland
Unspecified mental retardation[MUU ÄLYLLINEN KEHITYSVAMMAISUUS,EI KÄYTTÄYTYMIHÄIRI]
54.2
9.6
11
*
IEY01
NOMESCO Finland
Psychoeducation, individual
4.1
9.5
36
88
A04
ICPC
Weakness/tiredness general
1.6
9.5
288
1902
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.5
9.5
370
2589
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
3.4
9.5
45
133
R41.3
ICD-10 Finland
Other amnesia
3.8
9.5
39
103
P72
ICPC
Schizophrenia
3.3
9.5
46
139
N06AX16
ATC
venlafaxine; oral
1.6
9.5
226
1407
RD210
NOMESCO Finland
NA
2.4
9.4
75
309
SAA04
NOMESCO Finland
Special inverstigation of mouth
1.8
9.4
171
982
N28
ICPC
Limited function/disability (N)
5.0
9.4
29
58
3170A
ICD-9 Finland
Mild mental retardation[LIEVÄ ÄLYLL.KEHITYSVAMMAISUUS,EI KÄYTÄYTYM.HÄIRIÖTÄ]
98.6
9.3
10
*
SPAT1234
SPAT
Support of social functional capacity
2.4
9.3
77
322
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.9
9.3
126
654
F94.0
ICD-10 Finland
Elective mutism
17.3
9.3
14
8
H90.0
ICD-10 Finland
Conductive hearing loss, bilateral
6.1
9.2
24
39
Z31.5
ICD-10 Finland
Genetic counselling
2.1
9.2
108
528
L12
ICPC
Hand/finger symptom/complaint
1.5
9.2
306
2069
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
3.0
9.2
50
164
D12
ICPC
Constipation
2.7
9.2
62
232
K89
ICPC
Transient cerebral ischaemia
8.5
9.2
19
22
ZXA00
NOMESCO Finland
Right side
1.5
9.1
326
2239
N06AB06
ATC
sertraline; oral
1.7
9.1
199
1208
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
3.9
9.1
36
92
C07AB02
ATC
metoprolol; systemic
1.7
9.1
192
1153
3812A
ICD-9 Finland
Nonsuppurative otitis media and Eustachian tube disorders, Chronic mucoid otitis media
2.4
9.1
76
321
F93.9
ICD-10 Finland
Childhood emotional disorder, unspecified
4.5
9.1
31
69
N03AX18
ATC
lacosamide; systemic
5.0
9.1
28
56
XF404
NOMESCO Finland
Ambulatory ECG
1.9
9.1
128
675
Q87.88
ICD-10 Finland
Other specified congenital malformation syndromes, not elsewhere classified
13.5
9.1
15
11
F99
ICD-10 Finland
Mental disorder, not otherwise specified
2.8
9.0
57
205
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.3
9.0
1016
8525
F60.9
ICD-10 Finland
Personality disorder, unspecified
3.6
9.0
39
108
P20
ICPC
Memory disturbance
2.0
8.9
113
573
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.2
8.9
92
428
Z03.2
ICD-10 Finland
Observation for suspected mental and behavioural disorders
2.7
8.9
60
224
IGP01
NOMESCO Finland
Psychiatric family contact
2.8
8.9
56
201
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.9
8.9
120
622
R11
ICD-10 Finland
Nausea and vomiting
1.7
8.8
173
1016
N06AB10
ATC
escitalopram; oral
1.5
8.8
376
2677
H65.3
ICD-10 Finland
Chronic mucoid otitis media
1.8
8.8
141
777
F92.9
ICD-10 Finland
Mixed disorder of conduct and emotions, unspecified
4.4
8.8
30
67
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.7
8.8
174
1025
N05AF03
ATC
chlorprothixene; systemic
3.0
8.7
50
168
RS211
NOMESCO Finland
NA
4.3
8.7
31
72
N06AB03
ATC
fluoxetine; oral
1.7
8.7
187
1131
R25.1
ICD-10 Finland
Tremor, unspecified
3.1
8.7
45
143
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.7
8.7
163
946
SPAT1229
SPAT
Assessment of need for aid
2.2
8.7
89
415
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
3.9
8.6
34
87
I10
ICD-10 Finland
Essential (primary) hypertension
1.4
8.6
466
3475
K59.0
ICD-10 Finland
Constipation
2.1
8.5
95
459
RK320
NOMESCO Finland
NA
6.5
8.5
21
32
SAA03
NOMESCO Finland
Extended examination of mouth
1.3
8.5
905
7507
R07.4
ICD-10 Finland
Chest pain, unspecified
1.5
8.5
306
2105
IBZ06
NOMESCO Finland
Evaluation concerning developmental neuropsychiatry
4.4
8.5
29
65
B01AA03
ATC
warfarin; systemic
1.7
8.5
178
1068
R27.0
ICD-10 Finland
Ataxia, unspecified
11.4
8.5
15
13
DFF00
NOMESCO Finland
Pure tone audiometry
1.9
8.5
113
584
G12.2
ICD-10 Finland
Motor neuron disease
16.0
8.5
13
8
SCA02
NOMESCO Finland
Analysis and advice of nutrition with regard to dentistry
1.4
8.4
380
2734
ZXE40
NOMESCO Finland
More than seven and less than nine hours
2.8
8.4
53
189
IBA04
NOMESCO Finland
Extensive initial psychiatric evaluation
2.4
8.4
68
282
H52.0
ICD-10 Finland
Hypermetropia
2.6
8.4
61
238
ZXD20
NOMESCO Finland
Day surgery
1.7
8.4
193
1189
Q87.06
ICD-10 Finland
Velocardiofacial syndrome
88.7
8.4
9
*
EMB30
NOMESCO Finland
Adenotomy
1.6
8.3
210
1326
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.0
8.3
106
539
F92.8
ICD-10 Finland
Other mixed disorders of conduct and emotions
5.3
8.3
24
45
78151
ICD-8 Finland
Other symptoms referable to nervous system and special senses, Aphasia
+∞
8.3
8
*
34408
ICD-8 Finland
Other cerebral paralysis, Alia definita
+∞
8.3
8
*
R53
ICD-10 Finland
Malaise and fatigue
1.5
8.3
325
2278
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
2.8
8.3
52
186
WX402
NOMESCO Finland
General anaesthesia
1.5
8.2
275
1858
N04AA02
ATC
biperiden; systemic
3.6
8.2
35
96
ZY000
NOMESCO Finland
Hospital inpatient
2.8
8.2
52
187
SPAT1033
SPAT
Irrigation or wax removal of outer auditory canal
1.6
8.2
233
1516
IBA01
NOMESCO Finland
Diagnostic and symptom-mapping evaluation
2.4
8.2
69
291
RS314
NOMESCO Finland
NA
10.6
8.2
15
14
EB1WA
NOMESCO Finland
NA
5.2
8.2
24
46
R49.08
ICD-10 Finland
Other specified dysphonia
4.1
8.1
30
73
UDC00
NOMESCO Finland
Ear microscopy
1.8
8.1
147
844
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
1.5
8.0
250
1664
H01
ICPC
Ear pain/earache
1.5
8.0
281
1920
F98.00
ICD-10 Finland
Nonorganic enuresis nocturna
3.4
8.0
37
109
FM2CE
NOMESCO Finland
NA
2.4
8.0
65
271
F98.5
ICD-10 Finland
Stuttering [stammering]
11.5
8.0
14
12
RT250
NOMESCO Finland
NA
8.0
8.0
17
21
P28
ICPC
Limited function/disability (P)
4.6
8.0
26
56
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.4
7.9
358
2573
G81.1
ICD-10 Finland
Spastic hemiplegia
21.7
7.9
11
5
WX704
NOMESCO Finland
Intubation
1.9
7.9
105
543
K07.24
ICD-10 Finland
Open bite
2.7
7.9
52
194
SPAT1389
SPAT
Visit based on need for special support
1.7
7.9
151
884
G40.89
ICD-10 Finland
Other epilepsy
6.2
7.9
20
32
R4140
NOMESCO Finland
Psychotherapy
3.8
7.9
31
80
J01DB01
ATC
cefalexin; oral
1.3
7.9
1506
13498
101
Kela drug reimbursment
Anterior pituitary hypofunction
3.6
7.9
33
90
N05AF05
ATC
zuclopenthixol; systemic
5.2
7.9
23
44
I63.5
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
5.8
7.9
21
36
K00.40
ICD-10 Finland
Postnatal enamel hypoplasia
2.7
7.8
52
195
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.3
7.8
860
7140
XF402
NOMESCO Finland
ECG with work load test
1.9
7.8
114
611
JDB10
NOMESCO Finland
Percutaneous gastrostomy
4.8
7.7
24
49
WX110
SPAT
NA
2.0
7.7
95
477
ZXY82
NOMESCO Finland
Nurse in multidisciplinary team
4.0
7.7
29
72
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
1.8
7.7
117
637
A03
ICPC
Fever
1.4
7.6
451
3408
H03AA01
ATC
levothyroxine sodium; systemic
1.5
7.6
262
1784
N01
ICPC
Headache
1.4
7.6
369
2693
N88
ICPC
Epilepsy
4.9
7.6
23
46
ZXY01
NOMESCO Finland
Chief Physician, Head of Department or Deputy Chief Physician
3.6
7.6
32
88
K08.3
ICD-10 Finland
Retained dental root
2.1
7.6
83
399
ZXY80
NOMESCO Finland
Doctor in multidisciplinary team
4.2
7.5
27
64
XA400
NOMESCO Finland
EEG
5.5
7.5
21
38
Z00.8
ICD-10 Finland
Other general examinations
1.7
7.5
154
921
RS122
NOMESCO Finland
NA
7.9
7.5
16
20
F79.9
ICD-10 Finland
Unspecified mental retardation, without mention of impairment of behaviour
11.7
7.5
13
11
RT190
NOMESCO Finland
NA
11.7
7.5
13
11
602
Kela drug reimbursment
Children's severe malnutrition
3.0
7.4
40
132
SAA01
NOMESCO Finland
Simple examination of mouth
1.3
7.4
1423
12689
4122
FHL
Tympanostomy (tympanic tube)
2.1
7.4
84
408
R06.0
ICD-10 Finland
Dyspnoea
1.5
7.4
305
2153
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.3
7.4
1045
8950
A99
ICPC
Disease/condition unspecnature/site
1.8
7.4
124
697
WZC10
NOMESCO Finland
Extensive specialist consultion with written report
2.0
7.4
91
459
X44
ICD-10 Finland
Accidental poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
2.8
7.4
44
155
F93.89
ICD-10 Finland
Other childhood emotional disorders
2.4
7.4
58
238
J45.1
ICD-10 Finland
Nonallergic asthma
1.7
7.4
139
808
E23.01
ICD-10 Finland
Isolated deficiency of growth hormone
4.6
7.4
24
52
A41.9
ICD-10 Finland
Sepsis, unspecified
2.4
7.3
59
247
P15
ICPC
Chronic alcohol abuse
2.7
7.3
47
172
A49.9
ICD-10 Finland
Bacterial infection, unspecified
1.8
7.3
119
661
F95.2
ICD-10 Finland
Combined vocal and multiple motor tic disorder [de la Tourette]
7.5
7.3
16
21
G40.1
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
7.5
7.3
16
21
J35.2
ICD-10 Finland
Hypertrophy of adenoids
1.7
7.3
155
937
G40.4
ICD-10 Finland
Other generalized epilepsy and epileptic syndromes
5.9
7.3
19
32
H90.6
ICD-10 Finland
Mixed conductive and sensorineural hearing loss, bilateral
4.2
7.3
26
62
N05AA01
ATC
chlorpromazine; systemic, rectal
5.2
7.3
21
40
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.1
7.2
80
384
G45.8
ICD-10 Finland
Other transient cerebral ischaemic attacks and related syndromes
8.2
7.2
15
18
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
3.9
7.2
28
72
SBB10
NOMESCO Finland
Teeth copy
1.5
7.2
264
1821
D10
ICPC
Vomiting
1.6
7.1
193
1244
IEP03
NOMESCO Finland
Focused parental counselling
3.5
7.1
31
88
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
7.1
1035
8885
C09CA01
ATC
losartan; oral
1.6
7.1
194
1253
RT130
NOMESCO Finland
NA
7.2
7.1
16
22
ZXD31
NOMESCO Finland
Major difficulties in performing procedure
2.2
7.1
65
290
U04
ICPC
Incontinence urine
2.5
7.1
51
202
K92.0
ICD-10 Finland
Haematemesis
3.1
7.1
36
115
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
1.7
7.1
135
792
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
7.0
899
7581
R33
ICD-10 Finland
Retention of urine
2.1
7.0
72
336
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
2.8
7.0
43
155
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
2.6
7.0
49
189
3459X
ICD-9 Finland
Epilepsy, unspecified
11.8
7.0
12
10
EBA00
NOMESCO Finland
Extraction of tooth
1.3
7.0
713
5836
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
2.4
7.0
58
244
TJD20
NOMESCO Finland
Change of gastrostomy tube
5.5
6.9
19
34
G80.0
ICD-10 Finland
Spastic quadriplegic cerebral palsy
9.9
6.9
13
13
G80.9
ICD-10 Finland
Cerebral palsy, unspecified
9.9
6.9
13
13
IBB02
NOMESCO Finland
Psychiatric evaluation of working capacity and rehabilitation
4.0
6.9
26
65
SPAT1245
SPAT
Provision of support and information to patient’s family members
2.2
6.9
64
287
P22.0
ICD-10 Finland
Respiratory distress syndrome of newborn
6.9
6.9
16
23
B01AF02
ATC
apixaban; oral
2.0
6.9
82
408
WZB00
SPAT
NA
0.6
6.9
98
1581
SJB00
NOMESCO Finland
Fitting of loose orthodontic device with user information
1.7
6.9
151
921
201
Kela drug reimbursment
Chronic cardiac insufficiency
2.4
6.9
56
237
W19
ICD-10 Finland
Unspecified fall
1.6
6.8
173
1095
S06.0
ICD-10 Finland
Concussion
1.5
6.8
222
1492
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.4
6.8
375
2794
RS230
NOMESCO Finland
NA
6.2
6.8
17
27
T82
ICPC
Obesity
2.3
6.8
60
261
T50.9
ICD-10 Finland
Poisoning: Other and unspecified drugs, medicaments and biological substances
5.1
6.8
20
39
AA5PD
NOMESCO Finland
CT examination of brain pefusion
5.7
6.8
18
31
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.4
6.8
301
2156
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.1
6.8
77
375
F43.1
ICD-10 Finland
Post-traumatic stress disorder
2.2
6.8
66
303
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
6.8
266
1861
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
3.3
6.8
32
97
ZXE21
NOMESCO Finland
Procedure duration at least 3 but less than 4 hours
4.2
6.8
24
57
SPAT1301
SPAT
No procedures
1.3
6.8
571
4547
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.5
6.8
267
1870
ZXE50
NOMESCO Finland
More than nine and less than 12 hours
3.4
6.7
30
87
Q98.5
ICD-10 Finland
Karyotype 47,XYY
39.3
6.7
8
*
ICC03
NOMESCO Finland
Psychiatric treatment plan, transfer to psychiatric ward
4.9
6.7
20
40
RS214
NOMESCO Finland
NA
4.9
6.7
20
40
F31.1
ICD-10 Finland
Bipolar affective disorder, current episode manic without psychotic symptoms
4.9
6.7
20
40
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.3
6.7
861
7257
TFC99
NOMESCO Finland
Catheterisation of heart with other procedure
4.1
6.7
24
58
RT120
NOMESCO Finland
NA
6.0
6.7
17
28
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
6.0
6.7
17
28
S21
ICPC
Skin texture symptom/complaint
1.5
6.7
201
1328
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.5
6.7
195
1278
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
1.8
6.6
106
586
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.3
6.6
1058
9153
EB1CA
NOMESCO Finland
Tooth X-ray additional picture
1.6
6.6
152
939
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
3.2
6.6
32
99
KMAK
NOMESCO Finland
NA
1.3
6.6
856
7218
XX1XW
NOMESCO Finland
Extensive written report from radiologist
3.1
6.6
33
105
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
4.8
6.5
20
41
H90.5
ICD-10 Finland
Sensorineural hearing loss, unspecified
4.8
6.5
20
41
F60.8
ICD-10 Finland
Other specific personality disorders
4.8
6.5
20
41
AA5HE
NOMESCO Finland
Brain ultrasound examination in a child
2.9
6.5
36
122
SPAT1254
SPAT
Administration of medicine
1.4
6.5
330
2420
IBB01
NOMESCO Finland
Psychiatric functioning capacity evaluation
6.3
6.5
16
25
WX730
NOMESCO Finland
Conventional respirator
3.5
6.5
28
79
H50.1
ICD-10 Finland
Divergent concomitant strabismus
3.6
6.5
27
74
DFE00
NOMESCO Finland
Insertion of cochlear implant
7.7
6.5
14
18
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.6
6.5
183
1188
R05
ICD-10 Finland
Cough
1.4
6.5
305
2208
EB1JA
NOMESCO Finland
Double panorama tomography of teeth and jaws or similar X-ray examination
5.8
6.5
17
29
ZXE60
NOMESCO Finland
More than 12 and less than 15 hours
5.8
6.5
17
29
J21.9
ICD-10 Finland
Acute bronchiolitis, unspecified
2.0
6.5
77
382
RS120
NOMESCO Finland
NA
5.4
6.5
18
33
ZXY03
NOMESCO Finland
Occupational therapist
5.4
6.5
18
33
F39
ICD-10 Finland
Unspecified mood [affective] disorder
2.3
6.5
55
235
D21
ICPC
Swallowing problem
4.1
6.5
23
55
F31.0
ICD-10 Finland
Bipolar affective disorder, current episode hypomanic
3.3
6.5
30
90
290
Kela drug reimbursment
Apixaban, dabigatran, edoxaban and rivaroxaban for the treatment of atrial fibrillation
1.8
6.5
110
621
C07AB07
ATC
bisoprolol; oral
1.4
6.5
419
3203
P01
ICPC
Feeling anxious/nervous/tense
1.4
6.4
335
2472
WYA30
SPAT
NA
4.7
6.4
20
42
X59
ICD-10 Finland
Exposure to unspecified factor
1.4
6.4
328
2413
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
1.9
6.4
83
429
Q38.1
ICD-10 Finland
Ankyloglossia
2.9
6.4
37
128
ZXE01
NOMESCO Finland
Procedure duration 0 to 9 minutes
2.6
6.4
42
158
F31.30
ICD-10 Finland
Bipolar disorder Depressive episode without somatic syndrome
2.6
6.4
43
165
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
1.9
6.4
87
459
A11CC03
ATC
alfacalcidol; systemic
2.9
6.3
35
119
H65.1
ICD-10 Finland
Other acute nonsuppurative otitis media
2.0
6.3
74
367
WX872
NOMESCO Finland
Intensive care
2.2
6.3
59
264
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
2.2
6.3
57
254
WYA20
NOMESCO Finland
Home visit
3.5
6.2
27
77
H50.2
ICD-10 Finland
Vertical strabismus
4.8
6.2
19
39
Z01.2
ICD-10 Finland
Dental examination
1.3
6.2
858
7275
RS141
NOMESCO Finland
NA
10.8
6.2
11
10
30610
ICD-8 Finland
Special symptoms not elsewhere classified, Specific learning disturbance
+∞
6.2
6
*
F81.2
ICD-10 Finland
Specific disorder of arithmetical skills
+∞
6.2
6
*
ZXY84
NOMESCO Finland
Occupational therapist in multidisciplinary team
9.1
6.2
12
13
H29
ICPC
Ear symptom/complaint other
1.6
6.2
151
948
N05AE03
ATC
sertindole; oral
5.9
6.2
16
27
XX4BW
NOMESCO Finland
NA
5.9
6.2
16
27
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.5
6.2
193
1286
ZXD30
NOMESCO Finland
Difficulties in perfomrming procedure
1.9
6.2
83
432
207
Kela drug reimbursment
Chronic arrhythmias
1.7
6.2
115
671
Z25
ICPC
Assault/harmful event problem
3.1
6.2
31
99
F92.0
ICD-10 Finland
Depressive conduct disorder
3.3
6.2
28
83
G80.3
ICD-10 Finland
Dyskinetic cerebral palsy
26.3
6.2
8
*
Q93.8
ICD-10 Finland
Other deletions from the autosomes
26.3
6.2
8
*
R20.2
ICD-10 Finland
Paraesthesia of skin
1.8
6.2
95
523
A05
ICPC
Feeling ill
1.5
6.1
240
1675
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
1.6
6.1
139
854
G04BD12
ATC
mirabegron; oral
1.9
6.1
87
466
Z72.8
ICD-10 Finland
Other problems related to lifestyle
4.2
6.1
21
49
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.1
6.1
63
297
Z07
ICPC
Education problem
2.5
6.1
45
182
IER04
NOMESCO Finland
Rehabilitative psychiatric group intervention, functional
3.0
6.1
32
106
N05CF01
ATC
zopiclone; oral
1.4
6.1
317
2340
W10
ICD-10 Finland
Fall on and from stairs and steps
2.0
6.1
70
347
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
3.5
6.0
26
74
Z35.7
ICD-10 Finland
Supervision of high-risk pregnancy due to social problems
5.6
6.0
16
28
RS312
NOMESCO Finland
NA
7.5
6.0
13
17
P74
ICPC
Anxiety disorder/anxiety state
1.7
6.0
108
622
3454A
ICD-9 Finland
Epilepsy, Partial epilepsy, with impairment of consciousness[EPILEPSIA GENERALISATA SECUNDARIA]
12.3
6.0
10
8

Mortality – FinRegistry

Association

Association between endpoint F5_SPEECH and mortality.

Females

Parameter HR [95% CI] p-value
F5_SPEECH 2.33 [1.63, 3.33] < 0.001
Birth year 0.997 [0.99, 1.01] 0.521

During the follow-up period (1.1.1998 — 31.12.2019), 456 out of 16064 females with F5_SPEECH died.

Males

Parameter HR [95% CI] p-value
F5_SPEECH 1.96 [1.3, 2.95] 0.001
Birth year 0.986 [0.98, 1.0] 0.004

During the follow-up period (1.1.1998 — 31.12.2019), 439 out of 36866 males with F5_SPEECH died.

Mortality risk

Mortality risk for people of age

years, who have F5_SPEECH.

N-year risk Females Males
1 0.163% 0.335%
5 1.268% 2.075%
10 3.551% 5.315%
15 6.847% 10.057%
20 12.053% 16.402%

Relationships between endpoints

Index endpoint: F5_SPEECH – Specific development disorders of speech and language

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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