Disorders of oesophagus in diseases classified elsewhere

K11_DISOESINOTH

esophageal disease: A non-neoplastic or neoplastic disorder that affects the esophagus. Representative examples of non-neoplastic disorders include esophagitis and esophageal ulcer. Representative examples of neoplastic disorders include carcinomas, lymphomas, and melanomas.

Suggest a new description

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 K23*
  • Cause of death: ICD-10 K23*

2 out of 7 registries used, show all original rules.

712

4. Check minimum number of events

None

712

5. Include endpoints

None

712

6. Filter based on genotype QC (FinnGen only)

712

Control definitions (FinnGen only)

Control exclude
K11_OESSTODUO

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4359 2111 2210
Only index persons 3741 1874 1867
Unadjusted period prevalence (%)
Whole population 0.06 0.06 0.06
Only index persons 0.07 0.07 0.07
Median age at first event (years)
Whole population 68.90 69.62 68.24
Only index persons 68.35 68.82 67.87

-FinnGen-

Key figures

All Female Male
Number of individuals 712 350 362
Unadjusted period prevalence (%) 0.14 0.12 0.16
Median age at first event (years) 66.42 64.22 68.54

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
643
Matched controls
6430
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
55.7
323.0
554
645
K23.8*B37.8
ICD-10 Finland
Esophagitis caused by candidiasis
4503599627370496.0
323.0
540
*
J02AC01
ATC
fluconazole; systemic
8.0
127.1
448
1438
K23.8
ICD-10 Finland
Disorders of oesophagus in other diseases classified elsewhere
+∞
126.3
117
*
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
47.2
118.1
144
39
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
22.9
72.2
106
55
A02BC02
ATC
pantoprazole; systemic
4.9
67.0
518
2933
A07AA02
ATC
nystatin; oral
10.3
65.9
138
166
GD1AA
NOMESCO Finland
Thorax X-ray examination
4.2
63.3
422
2017
UJF32
NOMESCO Finland
Coloscopy
4.6
63.1
290
979
J45.9
ICD-10 Finland
Asthma, unspecified
5.2
60.6
226
608
H02AB06
ATC
prednisolone; systemic
4.0
60.1
424
2089
J18.9
ICD-10 Finland
Pneumonia, unspecified
4.4
60.1
292
1028
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.8
54.4
175
390
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
10.3
52.5
108
123
A02BC05
ATC
esomeprazole; systemic
3.7
51.5
333
1452
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
4.3
50.5
227
717
K29.3
ICD-10 Finland
Chronic superficial gastritis
141.1
49.6
52
*
R13
ICD-10 Finland
Dysphagia
9.6
49.0
105
128
K29.7
ICD-10 Finland
Gastritis, unspecified
72.0
46.9
53
8
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.5
45.1
288
1203
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
7.3
43.3
111
179
B37.8
ICD-10 Finland
Candidiasis of other sites
229.9
42.4
43
*
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
4.1
42.2
193
604
H02AB04
ATC
methylprednisolone; systemic
4.4
40.8
172
496
R03BB04
ATC
tiotropium bromide; inhalant
5.0
40.4
143
345
C03CA01
ATC
furosemide; systemic
3.2
40.3
293
1319
A02BC01
ATC
omeprazole; systemic
3.4
40.2
254
1033
R03AC02
ATC
salbutamol; inhalant
3.0
38.4
393
2214
D64.9
ICD-10 Finland
Anaemia, unspecified
4.8
37.0
135
334
K22.1
ICD-10 Finland
Ulcer of oesophagus
+∞
36.8
35
*
UJD02
NOMESCO Finland
Gastroscopy
11.2
35.8
69
68
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
3.0
35.6
305
1500
N02AX02
ATC
tramadol; systemic, rectal
2.9
35.5
350
1887
K20
ICD-10 Finland
Oesophagitis
83.0
35.2
39
5
R03AK06
ATC
salmeterol and fluticasone; inhalant
4.0
35.1
163
507
R06.0
ICD-10 Finland
Dyspnoea
3.2
34.5
237
997
R03DC03
ATC
montelukast; oral
4.0
33.8
154
469
J01MA12
ATC
levofloxacin; systemic
3.5
33.6
191
696
A49.9
ICD-10 Finland
Bacterial infection, unspecified
4.2
32.9
139
394
J45.0
ICD-10 Finland
Predominantly allergic asthma
5.6
32.0
99
201
K22.2
ICD-10 Finland
Oesophageal obstruction
328.0
31.1
31
*
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
4.6
31.1
117
295
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
3.8
31.1
152
489
L04AX01
ATC
azathioprine; systemic
8.8
30.9
68
85
UGC12
NOMESCO Finland
Flexible bronchoscopy
5.2
30.9
103
228
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
7.7
30.8
74
107
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
3.4
30.3
175
639
N03AX16
ATC
pregabalin; oral
3.0
29.4
210
891
A06AD11
ATC
lactulose; oral
3.6
29.3
150
499
J01MA14
ATC
moxifloxacin; systemic
4.5
29.0
111
284
JCA55
NOMESCO Finland
Endoscopic dilatation of oesophagus
157.0
28.9
30
*
GD1DD
NOMESCO Finland
High resolution CT examination of lungs
6.4
28.2
77
133
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
5.7
28.0
85
168
K29.5
ICD-10 Finland
Chronic gastritis, unspecified
39.8
27.3
34
9
J45
ICD-10 Finland
Asthma
4.4
27.3
107
279
UJF30
NOMESCO Finland
Ileoscopy through colon
4.7
27.1
98
236
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
3.9
26.9
121
358
A02BA02
ATC
ranitidine; systemic
3.1
26.9
172
671
K25.9
ICD-10 Finland
Gastric ulcer, Unspecified as acute or chronic, without haemorrhage or perforation
146.1
26.8
28
*
A02BC03
ATC
lansoprazole; oral
2.7
26.6
233
1110
R11
ICD-10 Finland
Nausea and vomiting
5.1
26.4
88
194
R03BA05
ATC
fluticasone; inhalant
3.2
26.0
163
625
H02AB07
ATC
prednisone; oral
3.5
25.9
139
475
K30
ICD-10 Finland
Functional dyspepsia
5.7
25.5
77
151
J01.0
ICD-10 Finland
Acute maxillary sinusitis
3.1
25.4
163
634
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
4.0
25.3
111
321
J45.1
ICD-10 Finland
Nonallergic asthma
4.9
25.3
88
203
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
4.4
24.8
96
247
R10.1
ICD-10 Finland
Pain localized to upper abdomen
3.4
24.6
132
448
127
Kela drug reimbursment
Transplant complication
20.0
24.2
36
19
L04AD01
ATC
ciclosporin; systemic
15.9
24.1
39
26
A01AB09
ATC
miconazole; local oral
4.1
23.8
99
272
K92.0
ICD-10 Finland
Haematemesis
13.6
23.7
41
32
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
5.2
23.4
76
162
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.0
23.3
158
633
K92.1
ICD-10 Finland
Melaena
5.7
22.6
67
128
R01AD08
ATC
fluticasone; nasal
2.6
22.2
201
957
TGC00
NOMESCO Finland
Bronchial lavation
9.1
22.2
47
55
R03BA01
ATC
beclometasone; inhalant
3.1
21.8
135
507
JBC01
NOMESCO Finland
Laparoscopic gastro-oesophageal antireflux operation
83.1
21.8
24
*
L04AA06
ATC
mycophenolic acid; systemic
13.9
21.7
37
28
JN3BD
NOMESCO Finland
Extensive abdominal CT
3.5
21.5
108
348
R50.9
ICD-10 Finland
Fever, unspecified
3.1
21.1
133
504
K22.4
ICD-10 Finland
Dyskinesia of oesophagus
+∞
20.9
20
*
K25.3
ICD-10 Finland
Gastric ulcer, Acute without haemorrhage or perforation
+∞
20.9
20
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
3.9
20.6
90
257
AA1AD
NOMESCO Finland
CT of head and brain
2.5
20.5
207
1036
J01MA02
ATC
ciprofloxacin; systemic
2.2
20.5
294
1756
A06AC01
ATC
ispaghula (psylla seeds); oral
2.5
20.3
192
927
A03FA02
ATC
cisapride; oral, rectal
4.2
20.2
80
209
J01FF01
ATC
clindamycin; systemic
2.4
19.9
206
1046
XG410
NOMESCO Finland
Flow-volume spirometry
6.6
19.8
52
85
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
5.6
19.8
59
114
GD1ED
NOMESCO Finland
Extensive high resolution CT examination of lungs
6.9
19.7
50
78
E0000UV
ATC
NA
2.2
19.7
276
1621
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.2
19.4
339
2189
H02AB09
ATC
hydrocortisone; systemic
9.8
19.4
39
42
R91
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
3.2
19.2
108
377
N17.9
ICD-10 Finland
Acute renal failure, unspecified
5.7
19.1
56
106
A03FA01
ATC
metoclopramide; systemic, rectal
2.6
19.1
168
779
R96
ICPC
Asthma
3.9
19.1
82
231
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
3.5
19.0
95
303
TK800
NOMESCO Finland
Hemodialysis
9.4
18.9
39
44
GD1BD
NOMESCO Finland
Thorax extensive CT-examination
4.7
18.8
66
153
R03AK07
ATC
formoterol and budesonide; inhalant
2.7
18.6
143
612
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.0
18.6
117
441
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.6
18.5
152
673
R03AC12
ATC
salmeterol; inhalant
5.3
18.5
58
119
N02BE01
ATC
paracetamol; systemic, rectal
2.7
18.4
562
4635
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.3
18.3
100
340
E87.6
ICD-10 Finland
Hypokalaemia
6.8
17.8
45
70
WW500
NOMESCO Finland
Blood transfusion
5.7
17.8
52
98
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
6.7
17.6
45
71
N03AX12
ATC
gabapentin; oral
2.8
17.5
125
510
P01AB01
ATC
metronidazole; oral, rectal
2.1
17.4
266
1597
D50.0
ICD-10 Finland
Iron deficiency anaemia secondary to blood loss (chronic)
6.7
17.2
44
70
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.7
17.2
131
554
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
2.2
17.1
243
1410
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
4.6
17.1
61
144
TPH04
NOMESCO Finland
Cathetrisation of vein
2.4
17.0
166
805
N06AX11
ATC
mirtazapine; oral
2.2
16.8
222
1244
UJF92
NOMESCO Finland
Capsular endoscopy
13.1
16.8
29
23
K25.7
ICD-10 Finland
Gastric ulcer, Chronic without haemorrhage or perforation
+∞
16.7
16
*
JN4BD
NOMESCO Finland
Extensive body CT
2.9
16.6
109
418
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
4.9
16.6
55
120
ZX120
NOMESCO Finland
Intravenous
3.3
16.4
86
284
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
3.1
16.4
97
349
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.3
16.3
88
297
J01FA06
ATC
roxithromycin; oral
2.1
16.2
275
1710
Z01.8
ICD-10 Finland
Other specified special examinations
2.4
16.2
160
781
N08.39*E10.2
ICD-10 Finland
Insulin-dependent diabetes mellitus - Diabetic nephropathy
48.8
16.1
19
*
N02AA05
ATC
oxycodone; systemic
2.6
16.0
131
577
J46
ICD-10 Finland
Status asthmaticus
6.6
15.9
41
66
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
6.6
15.9
41
66
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
3.7
15.9
72
212
J01DB01
ATC
cefalexin; oral
2.2
15.9
519
4191
A10AE04
ATC
insulin glargine; parenteral
3.2
15.7
88
304
JN4AD
NOMESCO Finland
Body CT examination
3.5
15.7
77
242
N06AX21
ATC
duloxetine; oral
3.2
15.7
87
299
JDW98
NOMESCO Finland
Other transluminal endoscopic operation on stomach or duodenum
19.8
15.6
23
12
K29.9
ICD-10 Finland
Gastroduodenitis, unspecified
87.2
15.6
17
*
K29.8
ICD-10 Finland
Duodenitis
163.8
15.5
16
*
R03DA04
ATC
theophylline; systemic, rectal
3.9
15.5
66
184
E000001
ATC
NA
2.4
15.4
151
731
R03BA02
ATC
budesonide; inhalant
2.5
15.4
134
607
R07.4
ICD-10 Finland
Chest pain, unspecified
2.2
15.3
194
1063
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
4.1
15.2
61
161
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.9
15.2
99
380
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
4.1
15.0
59
153
R03BA08
ATC
ciclesonide; inhalant
3.6
14.8
70
213
WX408
NOMESCO Finland
General anesthesy, balanced
2.2
14.8
194
1072
JN3AD
NOMESCO Finland
Abdominal CT examination
3.4
14.8
74
236
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
4.1
14.7
59
156
A02BC04
ATC
rabeprazole; oral
3.7
14.6
65
188
R06AE07
ATC
cetirizine; oral
2.0
14.6
271
1725
R63.8
ICD-10 Finland
Other symptoms and signs concerning food and fluid intake
82.0
14.6
16
*
R63.4
ICD-10 Finland
Abnormal weight loss
5.2
14.6
45
91
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.9
14.6
95
364
J01CA04
ATC
amoxicillin; systemic
2.1
14.3
498
4005
SPAT1263
SPAT
Sampling
2.0
14.3
286
1870
N05CF01
ATC
zopiclone; oral
2.0
14.2
233
1412
R53
ICD-10 Finland
Malaise and fatigue
2.3
14.2
151
756
ZXD05
NOMESCO Finland
Urgent procedure
2.0
14.2
222
1321
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
3.9
14.1
59
162
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.3
13.9
72
236
R03BB01
ATC
ipratropium bromide; inhalant
4.6
13.8
48
111
C03DA01
ATC
spironolactone; oral
2.7
13.6
98
399
R60.0
ICD-10 Finland
Localized oedema
2.7
13.6
97
392
J01AA02
ATC
doxycycline; systemic
2.0
13.6
497
4021
K29.0
ICD-10 Finland
Acute haemorrhagic gastritis
142.9
13.5
14
*
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.5
13.5
111
488
N06AB04
ATC
citalopram; systemic
2.2
13.3
152
786
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.8
13.2
91
361
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
3.2
13.1
71
240
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.9
13.1
290
1948
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
17.2
13.0
20
12
J01FA15
ATC
telithromycin; oral
3.1
13.0
73
252
R01AD09
ATC
mometasone; nasal
1.9
12.9
264
1725
GD1AD
NOMESCO Finland
Thorax CT examination
4.3
12.9
48
119
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.5
12.8
112
508
R51.80
ICD-10 Finland
Headache
2.6
12.7
97
406
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
3.7
12.6
55
157
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
4.8
12.5
41
89
R05
ICD-10 Finland
Cough
2.2
12.5
137
694
K26.3
ICD-10 Finland
Duodenal ulcer, acute without haemorrhage or perforation
132.5
12.5
13
*
K25.0
ICD-10 Finland
Gastric ulcer, Acute with haemorrhage
132.5
12.5
13
*
WX002
NOMESCO Finland
Sedation and analgesia
2.2
12.5
146
760
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
5.5
12.4
36
68
TDM10
NOMESCO Finland
Puncture of maxillary antrum
5.1
12.4
39
81
R03AC03
ATC
terbutaline; inhalant
2.5
12.4
101
439
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
4.9
12.3
40
86
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
5.5
12.3
36
69
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.9
12.2
220
1362
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.7
12.1
88
358
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.0
12.0
175
1000
A46
ICD-10 Finland
Erysipelas
2.3
12.0
116
553
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.9
12.0
208
1273
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.4
11.9
58
181
L28
ICPC
Limited function/disability (L)
2.2
11.8
128
642
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
5.4
11.8
35
68
J01FA09
ATC
clarithromycin; systemic
2.0
11.7
195
1171
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
3.8
11.7
50
141
A41.9
ICD-10 Finland
Sepsis, unspecified
4.7
11.7
39
87
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
3.8
11.6
49
136
E87.5
ICD-10 Finland
Hyperkalaemia
7.4
11.6
27
38
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.1
11.6
66
231
L04AA01
ATC
[U] ciclosporin; systemic
9.5
11.6
23
25
NF1AA
NOMESCO Finland
Hip X-ray examination
2.9
11.5
74
279
SPAT1325
SPAT
Vaccination
1.8
11.5
248
1633
K22.5
ICD-10 Finland
Diverticulum of oesophagus, acquired
+∞
11.5
11
*
M81.9
ICD-10 Finland
Osteoporosis, unspecified
4.5
11.5
40
93
ZXE20
NOMESCO Finland
More than three and less than five hours
2.3
11.5
111
529
UDH02
NOMESCO Finland
Rhinopharyngoscopy
3.6
11.4
52
154
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
7.2
11.4
27
39
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.8
11.4
268
1810
JN3CD
NOMESCO Finland
Abdominal CT examination both without and with contrast
4.6
11.4
39
89
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
2.9
11.4
73
275
N04BC05
ATC
pramipexole; oral
3.1
11.4
62
211
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
3.0
11.3
66
235
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.2
11.3
128
654
SPAT1249
SPAT
Treatment-related counselling outside office
1.8
11.2
259
1738
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
5.2
11.2
34
68
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
4.2
11.2
42
105
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
3.5
11.2
52
157
A07EA06
ATC
budesonide; oral, local oral
5.6
11.2
32
60
R03AK03
ATC
[D] fenoterol & other drugs for obstructive airway dis; inhalant
3.2
11.1
58
191
L30.9
ICD-10 Finland
Dermatitis, unspecified
2.2
11.1
121
607
SPAT1255
SPAT
Intravenous administration of medicine
3.0
11.1
65
233
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
5.2
10.9
33
66
M48.0
ICD-10 Finland
Spinal stenosis
2.4
10.9
97
440
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
4.1
10.9
42
108
-
ICD-10 Finland
NA
5.4
10.9
32
62
Z49.1
ICD-10 Finland
Extracorporeal dialysis
8.5
10.9
23
28
N06AA09
ATC
amitriptyline; systemic
2.6
10.9
81
335
137
Kela drug reimbursment
Uraemia requiring dialysis
15.8
10.9
17
11
I50.9
ICD-10 Finland
Heart failure, unspecified
2.2
10.9
118
593
R02
ICPC
Shortness of breath/dyspnoea
2.5
10.9
90
396
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
7.4
10.8
25
35
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
6.0
10.8
29
50
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.0
10.8
170
994
A10AA02
ATC
NA
5.0
10.8
34
71
C08CA05
ATC
nifedipine; systemic
3.0
10.8
62
218
I10
ICD-10 Finland
Essential (primary) hypertension
1.8
10.8
401
3115
K29.4
ICD-10 Finland
Chronic atrophic gastritis
18.2
10.8
16
9
E10.2
ICD-10 Finland
Type 1 diabetes mellitus, With renal complications
21.9
10.7
15
7
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
5.7
10.7
30
55
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.3
10.6
105
504
A01AB04
ATC
amphotericin B; local oral
3.9
10.5
43
117
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
3.1
10.5
59
204
D13.1
ICD-10 Finland
Benign neoplasm: Stomach
7.0
10.5
25
37
K25.4
ICD-10 Finland
Gastric ulcer, Chronic or unspecified with haemorrhage
+∞
10.4
10
*
R03AK08
ATC
formoterol and beclometasone; inhalant
4.6
10.4
35
79
B01AB05
ATC
enoxaparin; parenteral
1.8
10.4
209
1333
H04.10
ICD-10 Finland
Dry eye syndrome
2.7
10.4
71
278
A11CC03
ATC
alfacalcidol; systemic
5.9
10.4
28
49
J20
ICD-10 Finland
Acute bronchitis
2.8
10.4
69
268
JC2AB
NOMESCO Finland
Oesophagus X-ray examination with contrast
23.8
10.3
14
6
K59.0
ICD-10 Finland
Constipation
3.6
10.3
45
130
A10AA01
ATC
NA
6.4
10.2
26
42
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
3.3
10.2
51
163
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.9
10.2
62
226
R42
ICD-10 Finland
Dizziness and giddiness
2.0
10.1
150
856
N05AH04
ATC
quetiapine; oral
2.3
10.1
100
480
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.8
10.1
247
1675
C07AB07
ATC
bisoprolol; oral
1.7
10.1
325
2398
B03BA03
ATC
hydroxocobalamin; parenteral
3.4
10.1
49
154
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.1
10.0
118
612
K29.6
ICD-10 Finland
Other gastritis
40.7
10.0
12
*
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
5.4
9.9
29
56
M79.6
ICD-10 Finland
Pain in limb
1.8
9.9
215
1401
Z2446
NOMESCO Finland
Social worker
3.1
9.9
53
179
N03AE01
ATC
clonazepam; systemic
3.4
9.9
48
151
A02BA04
ATC
nizatidine; systemic
2.8
9.8
62
233
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
4.1
9.8
37
94
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
2.8
9.8
65
252
XW000
NOMESCO Finland
Bone marrow biopsy
3.9
9.8
39
104
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.7
9.8
66
259
B01AC04
ATC
clopidogrel; oral
2.1
9.7
126
681
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
5.0
9.7
30
62
T89
ICPC
Diabetes insulin dependent
4.7
9.7
32
71
J01DA01
ATC
[U] cefalexin; systemic
1.7
9.7
384
2995
K29.1
ICD-10 Finland
Other acute gastritis
55.8
9.7
11
*
K22.7
ICD-10 Finland
Barrett oesophagus
55.8
9.7
11
*
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.9
9.7
169
1022
E11.8
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
2.5
9.6
77
332
A07EC02
ATC
mesalazine; oral, rectal
3.5
9.6
44
132
K51.5
ICD-10 Finland
Left sided colitis
5.8
9.6
26
46
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.6
9.6
70
286
L04AD02
ATC
tacrolimus; systemic (calcineurin inhibitors)
15.3
9.5
15
10
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.0
9.5
54
188
C08CA01
ATC
amlodipine; oral
1.7
9.5
250
1725
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
5.3
9.5
28
55
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
3.5
9.5
43
128
K22.8
ICD-10 Finland
Other specified diseases of oesophagus
101.5
9.4
10
*
C01DA14
ATC
isosorbide mononitrate; oral
2.1
9.4
118
629
M01AB55
ATC
diclofenac, combinations; oral
2.8
9.4
59
221
K22.9
ICD-10 Finland
Disease of oesophagus, unspecified
+∞
9.4
9
*
Z94.2
ICD-10 Finland
Lung transplant status
+∞
9.4
9
*
K26.9
ICD-10 Finland
Duodenal ulcer, unspecified as acute or chronic, without haemorrhage or perforation
+∞
9.4
9
*
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
1.7
9.4
228
1537
WX892
NOMESCO Finland
Monitored bed care
2.8
9.3
62
240
J47
ICD-10 Finland
Bronchiectasis
6.6
9.3
23
36
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
4.2
9.3
34
84
J01FA10
ATC
azithromycin; systemic
1.7
9.3
317
2358
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.8
9.3
172
1060
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
2.1
9.3
115
610
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
4.4
9.2
32
75
R01AD01
ATC
beclometasone; nasal
2.2
9.2
100
500
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
3.2
9.1
47
155
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.9
9.1
155
926
J22
ICD-10 Finland
Unspecified acute lower respiratory infection
3.5
9.1
41
122
V03AE01
ATC
polystyrene sulfonate; oral
9.2
9.1
18
20
SPAT1262
SPAT
Handing over of treatment supplies
2.0
9.0
135
769
Z94.4
ICD-10 Finland
Liver transplant status
37.2
9.0
11
*
J05AB11
ATC
valaciclovir; oral
2.3
9.0
88
418
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
6.7
9.0
22
34
M05BX04
ATC
denosumab; parenteral
3.3
9.0
45
145
A07EC01
ATC
sulfasalazine; oral, rectal
2.7
9.0
60
233
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.1
9.0
113
602
B07.9
ICD-10 Finland
Verruca simplex
4.6
9.0
30
68
JF1AB
NOMESCO Finland
Passage examination of small bowell with X-ray
8.1
8.9
19
24
N05CD07
ATC
temazepam; oral
2.2
8.9
98
493
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
3.1
8.8
48
164
E10.00
ICD-10 Finland
Insulin-dependent diabetes diabetic hypoglycemic coma
9.7
8.8
17
18
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.7
8.8
272
1953
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
5.0
8.8
27
56
K90.0
ICD-10 Finland
Coeliac disease
5.0
8.8
27
56
DMB20
NOMESCO Finland
Functional endoscopic opening of maxillary antrum
3.6
8.7
38
110
JJC00
NOMESCO Finland
Allogenic transplantation of liver
50.7
8.7
10
*
R01BA52
ATC
pseudoephedrine, combinations; oral
1.8
8.7
186
1198
K50.0
ICD-10 Finland
Crohn disease of small intestine
11.8
8.6
15
13
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.9
8.6
50
179
A05AA02
ATC
ursodeoxycholic acid; oral
10.2
8.6
16
16
S18
ICPC
Laceration/cut
1.7
8.6
265
1902
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.5
8.6
68
293
P01BA02
ATC
hydroxychloroquine; oral
2.6
8.5
61
247
UDQ12
NOMESCO Finland
Flexible laryngoscopy
3.4
8.5
40
123
K59.1
ICD-10 Finland
Functional diarrhoea
3.4
8.4
40
124
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.9
8.4
52
191
K56.6
ICD-10 Finland
Other and unspecified intestinal obstruction
4.0
8.4
32
83
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
3.0
8.4
48
170
GDG10
NOMESCO Finland
Bilateral transplantation of lung
+∞
8.3
8
*
K31.8
ICD-10 Finland
Other specified diseases of stomach and duodenum
+∞
8.3
8
*
K26.0
ICD-10 Finland
Duodenal ulcer, acute with haemorrhage
+∞
8.3
8
*
M05BA04
ATC
alendronic acid; oral
2.4
8.3
69
303
B37.09
ICD-10 Finland
Unspecified candidal stomatitis
10.9
8.3
15
14
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
3.4
8.3
39
120
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.9
8.3
144
863
L04AA13
ATC
leflunomide; oral
5.1
8.3
25
51
B81
ICPC
Anaemia vit B12/folate deficiency
3.8
8.3
34
94
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.8
8.2
165
1036
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
2.9
8.2
49
179
K83.0
ICD-10 Finland
Cholangitis
7.0
8.1
19
28
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.9
8.1
128
743
B37.08
ICD-10 Finland
Other candidal stomatitis
11.9
8.1
14
12
H26.3
ICD-10 Finland
Drug-induced cataract
17.4
8.1
12
7
M34.1
ICD-10 Finland
CR(E)ST syndrome
33.8
8.1
10
*
E11.00
ICD-10 Finland
Non-insulin dependent diabetes diabetic hypoglycaemic coma
3.7
8.1
34
96
J84.1
ICD-10 Finland
Other interstitial pulmonary diseases with fibrosis
5.4
8.1
23
44
D12.4
ICD-10 Finland
Benign neoplasm: Descending colon
6.4
8.1
20
32
A07AA09
ATC
vancomycin; oral
6.4
8.1
20
32
ZXE30
NOMESCO Finland
More than five and less than seven hours
3.0
8.0
46
163
WX872
NOMESCO Finland
Intensive care
2.9
8.0
47
170
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
2.8
8.0
51
194
JJ2AT
NOMESCO Finland
Biopsy of liver with ultrasound guidance
5.0
8.0
24
49
3AC01
NOMESCO Finland
NA
13.2
7.9
13
10
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
5.5
7.9
22
41
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
4.1
7.9
29
73
A02BA03
ATC
famotidine; systemic
3.9
7.9
31
83
N30
ICD-10 Finland
Cystitis
2.8
7.8
49
182
Z49.2
ICD-10 Finland
Other dialysis
11.0
7.8
14
13
A04AA01
ATC
ondansetron; systemic, rectal
2.9
7.8
47
173
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.2
7.8
39
127
UJC12
NOMESCO Finland
Flexible oesophagoscopy
15.2
7.7
12
8
DNB20
NOMESCO Finland
Endoscopic ethmoidectomy
5.7
7.7
21
38
UJF02
NOMESCO Finland
Peroral enteroscopy
45.5
7.7
9
*
I50.0
ICD-10 Finland
Congestive heart failure
2.5
7.7
60
256
M05BA07
ATC
risedronic acid; oral
3.6
7.7
33
95
W19
ICD-10 Finland
Unspecified fall
2.3
7.7
72
335
UKC02
NOMESCO Finland
Cystoscopy
1.9
7.7
116
663
DM1AD
NOMESCO Finland
CT of paranasal sinuses and face area
4.0
7.6
29
75
TPX10
NOMESCO Finland
Implantation of vascular injection port
3.9
7.6
30
80
K74.6
ICD-10 Finland
Other and unspecified cirrhosis of liver
6.8
7.6
18
27
4931A
ICD-9 Finland
Asthma, Intrinsic asthma[INTRINSIC ASTHMA SINE EXACERBATIONE]
8.2
7.6
16
20
E11.7
ICD-10 Finland
Type 2 diabetes mellitus, with multiple complications
2.9
7.6
44
157
SPAT1301
SPAT
No procedures
1.7
7.6
199
1352
K86.1
ICD-10 Finland
Other chronic pancreatitis
12.0
7.6
13
11
I45.9
ICD-10 Finland
Conduction disorder, unspecified
12.0
7.6
13
11
K70.3
ICD-10 Finland
Alcoholic cirrhosis of liver
6.3
7.6
19
31
4931B
ICD-9 Finland
Asthma, Intrinsic asthma[INTRINSIC ASTHMA CUM EXACERBATIONE]
25.3
7.6
10
*
B25.8
ICD-10 Finland
Other cytomegaloviral diseases
25.3
7.6
10
*
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.9
7.6
45
164
Z94.0
ICD-10 Finland
Kidney transplant status
9.0
7.6
15
17
M54.5
ICD-10 Finland
Low back pain
1.7
7.6
185
1231
Z3226
NOMESCO Finland
Physiotherapist
1.9
7.5
118
679
J45.8
ICD-10 Finland
Mixed asthma
4.2
7.5
27
67
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.6
7.4
54
220
A12AA04
ATC
calcium carbonate; oral
5.7
7.4
20
36
E16.2
ICD-10 Finland
Hypoglycaemia, unspecified
7.8
7.4
16
21
A04.8
ICD-10 Finland
Other specified bacterial intestinal infections
7.8
7.4
16
21
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
4.4
7.4
25
58
103
Kela drug reimbursment
Diabetes, insulin-treated
1.7
7.4
178
1179
R4180
NOMESCO Finland
Podiatric therapy
8.5
7.3
15
18
315
Kela drug reimbursment
Clopidogrel
8.5
7.3
15
18
D62
ICD-10 Finland
Acute posthaemorrhagic anaemia
8.5
7.3
15
18
TKC20
NOMESCO Finland
Catheterisation of bladder
2.5
7.3
58
250
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
7.3
115
664
H04AA01
ATC
glucagon; nasal, parenteral
7.0
7.3
17
25
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.7
7.3
180
1199
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
6.4
7.3
18
29
SBA00
NOMESCO Finland
Microbiological examinations
4.7
7.3
23
50
S97
ICPC
Chronic ulcer skin
2.6
7.3
50
199
A10AE05
ATC
insulin detemir; parenteral
2.9
7.2
42
151
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
2.3
7.2
69
325
SPAT1312
SPAT
General health counselling
1.7
7.2
190
1291
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
3.2
7.2
35
112
J84.9
ICD-10 Finland
Interstitial pulmonary disease, unspecified
4.6
7.1
23
51
D07AC01
ATC
betamethasone; topical
1.6
7.1
205
1428
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.0
7.1
88
466
N06AX16
ATC
venlafaxine; oral
2.2
7.1
73
357
H3603, E103
ICD-10 Finland
NA
10.2
7.1
13
13
WX882
NOMESCO Finland
High dependency care
3.9
7.0
27
71
M01AE03
ATC
ketoprofen; systemic, rectal
1.6
7.0
236
1709
D21
ICPC
Swallowing problem
7.1
7.0
16
23
N30.0
ICD-10 Finland
Acute cystitis
2.0
7.0
89
475
G04CA02
ATC
tamsulosin; oral
1.7
7.0
163
1067
R12
ICD-10 Finland
Heartburn
2.9
7.0
41
149
R06AX22
ATC
ebastine; oral
2.0
6.9
96
528
TJD00
NOMESCO Finland
Insertion of nasogastric or naso-gastroduodenal tube
7.6
6.9
15
20
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
3.1
6.9
36
121
M02AA07
ATC
piroxicam; topical
1.6
6.9
226
1623
SPAT1254
SPAT
Administration of medicine
1.9
6.9
105
600
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
6.9
108
622
R06AX13
ATC
loratadine; oral
2.1
6.9
82
425
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.7
6.9
155
1007
A12BA01
ATC
potassium chloride; oral
2.8
6.8
41
151
R95
ICPC
Chron obstructive pulmonary disease
3.9
6.8
26
68
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.7
6.8
146
933
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
4.6
6.8
22
49
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
3.0
6.8
37
128
E27.3
ICD-10 Finland
Drug-induced adrenocortical insufficiency
11.1
6.8
12
11
E10.1
ICD-10 Finland
Type 1 diabetes mellitus, With ketoacidosis
11.1
6.8
12
11
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
6.2
6.8
17
28
N08.39*E11.2
ICD-10 Finland
Non-insulin-dependent diabetes mellitus - Diabetic nephropathy
5.8
6.8
18
32
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
2.4
6.8
56
245
N19
ICD-10 Finland
Unspecified kidney failure
3.2
6.8
33
106
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.6
6.7
228
1649
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.9
6.7
26
69
JKE98
NOMESCO Finland
Other transduodenal endoscopic operation on bile duct or ampulla of Vater
7.3
6.7
15
21
PD4BC
NOMESCO Finland
Extensive arterigography of lower extremity with X-ray
5.0
6.7
20
41
SPAT1104
SPAT
Monitoring of emergency patient
2.5
6.7
51
216
M81.4
ICD-10 Finland
Drug-induced osteoporosis
22.8
6.7
9
*
C07AB02
ATC
metoprolol; systemic
1.7
6.7
146
938
N18.8
ICD-10 Finland
Other chronic renal failure
3.7
6.7
27
75
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
3.8
6.6
26
70
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.7
6.6
157
1030
K92.2
ICD-10 Finland
Gastrointestinal haemorrhage, unspecified
4.0
6.6
25
65
K86.00
ICD-10 Finland
Acute pancreatitis caused by alcohol
7.9
6.6
14
18
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.7
6.6
154
1006
K55.2
ICD-10 Finland
Angiodysplasia of colon
12.4
6.6
11
9
TGD04
NOMESCO Finland
Needle biopsy of the lungs in bronchoscopy
12.4
6.6
11
9
I20.09
ICD-10 Finland
Unstable angina
2.6
6.5
46
186
R04.2
ICD-10 Finland
Haemoptysis
3.4
6.5
29
87
D64.8
ICD-10 Finland
Other specified anaemias
5.4
6.5
18
34
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
2.1
6.5
75
383
S81.8
ICD-10 Finland
Open wound of other parts of lower leg
3.5
6.5
28
82
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
3.5
6.5
28
82
J96.1
ICD-10 Finland
Chronic respiratory failure
4.3
6.5
22
52
C10AC01
ATC
colestyramine; oral
4.3
6.5
22
52
K81.0
ICD-10 Finland
Acute cholecystitis
4.8
6.5
20
43
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
4.8
6.5
20
43
QXA25
NOMESCO Finland
Destruction of lesion of skin, site unspecified
3.7
6.4
26
72
M01AC06
ATC
meloxicam; systemic, rectal
1.6
6.4
215
1547
JCF12
NOMESCO Finland
Endoscopic insertion of prosthetic tube into oesphagus
70.5
6.4
7
*
K22.6
ICD-10 Finland
Gastro-oesophageal laceration-haemorrhage syndrome
70.5
6.4
7
*
R01AD05
ATC
budesonide; nasal
2.4
6.4
51
219
M35.1
ICD-10 Finland
Other overlap syndromes
14.5
6.4
10
7
GD2SN
NOMESCO Finland
Lung ventilation SPECT
14.5
6.4
10
7
GD1UN
NOMESCO Finland
Lung circulation SPECT
14.5
6.4
10
7
E11.1
ICD-10 Finland
Type 2 diabetes mellitus, with ketoacidosis
14.5
6.4
10
7
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.9
6.4
101
584
R03DC01
ATC
zafirlukast; oral
4.5
6.4
21
48
J09
ICD-10 Finland
Influenza due to identified zoonotic or pandemic influenza virus
4.5
6.4
21
48
B01AB04
ATC
dalteparin; parenteral
2.8
6.4
39
146
SPAT1240
SPAT
Therapeutic discussion
2.4
6.4
52
229
R70.0
ICD-10 Finland
Elevated erythrocyte sedimentation rate
4.3
6.4
22
53
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
3.7
6.4
26
73
N05BA06
ATC
lorazepam; systemic, sublingual
2.7
6.3
42
165
A09AA02
ATC
multienzymes (lipase, protease etc.)
4.7
6.3
20
44
B05DA
ATC
Isotonic solutions
11.2
6.3
11
10
ZX108
NOMESCO Finland
Inhalation
9.4
6.3
12
13
E10.4
ICD-10 Finland
Type 1 diabetes mellitus, With neurological complications
9.4
6.3
12
13
D07AA02
ATC
hydrocortisone; topical
2.0
6.3
78
413
ZXE06
NOMESCO Finland
Procedure duration 50 to 59 minutes
3.2
6.3
31
101
V03AE02
ATC
sevelamer; oral
18.2
6.3
9
5
DM1AI
NOMESCO Finland
Cone beam CT of paranasal sinus
4.9
6.3
19
40
R33
ICD-10 Finland
Retention of urine
2.2
6.3
61
292
5301A
ICD-9 Finland
Diseases of oesophagus, Oesophagitis[OESOPHAGITIS REFLUENS]
+∞
6.3
6
*
K28.9
ICD-10 Finland
Gastrojejunal ulcer, unspecified as acute or chronic, without haemorrhage or perforation
+∞
6.3
6
*
Q40.9
ICD-10 Finland
Congenital malformation of upper alimentary tract, unspecified
+∞
6.3
6
*
A07DA03
ATC
loperamide; oral
3.1
6.3
32
107
K86.08
ICD-10 Finland
Alcohol-induced chronic pancreatitis
26.9
6.2
8
*
R03AK11
ATC
formoterol and fluticasone; inhalant
4.0
6.2
23
59
A01AB10
ATC
natamycin; local oral
4.0
6.2
23
59
N05BA01
ATC
diazepam; systemic, rectal
2.0
6.2
85
465
SBB00
NOMESCO Finland
Fotograf of mouth and teeth
3.5
6.2
27
80
R03AC13
ATC
formoterol; inhalant
2.7
6.2
41
161
A02BD03
ATC
lansoprazole, amoxicillin and metronidazole; systemic
2.4
6.2
48
206
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
6.4
6.2
15
24
2500B
ICD-9 Finland
Diabetes mellitus without mention of complication[DIABETES MELLITUS SINE COMPLICATIONE ,TYYPPI I]
6.4
6.2
15
24
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
5.4
6.2
17
32
EP1AE
NOMESCO Finland
Neck ultrasound examination
2.5
6.2
44
180
NHQ40
NOMESCO Finland
Amputation of toe
4.3
6.2
21
50
A06AC51
ATC
ispaghula, combinations; systemic
3.0
6.2
35
123
N31.2
ICD-10 Finland
Flaccid neuropathic bladder, not elsewhere classified
7.8
6.1
13
17
B99
ICD-10 Finland
Other and unspecified infectious diseases
4.7
6.1
19
41
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
1.9
6.1
95
544
SPAT1229
SPAT
Assessment of need for aid
2.2
6.1
62
302
ZXE04
NOMESCO Finland
Procedure duration 30 to 39 minutes
2.6
6.1
41
163
P76
ICPC
Depressive disorder
2.9
6.1
35
125
B03XA02
ATC
darbepoetin alfa; parenteral
4.5
6.1
20
46
R05
ICPC
Cough
1.7
6.1
130
826
R03AL01
ATC
fenoterol and ipratropium bromide; inhalant
3.5
6.1
26
76
M35.9
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
8.7
6.1
12
14
N05BA04
ATC
oxazepam; oral
1.7
6.1
146
959
PF1AT
NOMESCO Finland
Intravascular dilatation of arteries of knee, lower leg and ankle (PTA)
6.8
6.1
14
21
J93.1
ICD-10 Finland
Other spontaneous pneumothorax
10.1
6.0
11
11
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
2.9
6.0
35
126
133
Kela drug reimbursment
Severe chronic pancreatic insufficiency
5.3
6.0
17
33
J30.0
ICD-10 Finland
Vasomotor rhinitis
4.0
6.0
22
56
J33.0
ICD-10 Finland
Polyp of nasal cavity
3.9
6.0
23
61
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
3.0
6.0
32
110
R03AK10
ATC
vilanterol and fluticasone furoate; inhalant
3.4
6.0
27
82
M02AA10
ATC
ketoprofen; topical
1.8
6.0
101
594
Z98.8
ICD-10 Finland
Other specified postsurgical states
6.1
6.0
15
25
L27.0
ICD-10 Finland
Generalized skin eruption due to drugs and medicaments
6.1
6.0
15
25
81
HP
Angiography of the heart and coronary arteries
2.4
6.0
51
227

Mortality – FinRegistry

Association

Association between endpoint K11_DISOESINOTH and mortality.

Females

Parameter HR [95% CI] p-value
K11_DISOESINOTH 2.565 [2.19, 3.01] < 0.001
Birth year 0.999 [0.99, 1.01] 0.903

During the follow-up period (1.1.1998 — 31.12.2019), 765 out of 1795 females with K11_DISOESINOTH died.

Males

Parameter HR [95% CI] p-value
K11_DISOESINOTH 3.311 [2.69, 4.07] < 0.001
Birth year 0.985 [0.97, 0.99] 0.002

During the follow-up period (1.1.1998 — 31.12.2019), 950 out of 1818 males with K11_DISOESINOTH died.

Mortality risk

Mortality risk for people of age

years, who have K11_DISOESINOTH.

N-year risk Females Males
1 0.301% 0.578%
5 1.533% 3.549%
10 4.232% 8.764%
15 8.451% 15.944%
20 14.532% 26.073%

Relationships between endpoints

Index endpoint: K11_DISOESINOTH – Disorders of oesophagus in diseases classified elsewhere

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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