info icon

Ulcerative colitis

K11_ULCER

ulcerative colitis: An inflammatory bowel disease involving the mucosal surface of the large intestine and rectum. It may present with an acute or slow onset and follows an intermittent or continuous course. Signs and symptoms include abdominal pain, diarrhea, fever, weight loss, and intestinal hemorrhage.

Endpoint definition

FinnGen phenotype data

414262 individuals

diagram downward connector

Apply sex-specific rule None

414262

diagram downward connector

Check conditions None

414262

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K51
Hospital discharge: ICD-9 556
Hospital discharge: ICD-8 5631|569
Hospital discharge: excluded ICD-9 5564A
Cause of death: ICD-10 K51
Cause of death: ICD-9 556
Cause of death: ICD-8 5631|569
Cause of death: excluded ICD-9 5564A

2 out of 7 registries used, show all original rules.

9325

diagram downward connector

Check minimum number of events None

9325

diagram downward connector

Include endpoints None

9325

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

8672

diagram downward connector
K11_ULCER

Control definitions

Control exclude K11_ENERCOLNONINF

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 K50-K52
Name in latin Colitis ulcerosa

Similar endpoints

List of similar endpoints to Ulcerative colitis based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 8672 4526 4146
Unadjusted prevalence (%) 2.30 2.15 2.49
Mean age at first event (years) 42.70 40.50 45.12

Mortality

Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.

Correlations

Index endpoint: K11_ULCER – Ulcerative colitis
GWS hits:

Survival analyses between endpoints

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Ulcerative colitis

Not a core endpoint, no data to show.