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Laparoscopic left hemicolectomy

OPER_JFB44

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Operations: NOMESCO codes ^JFB44

1 out of 7 registries used, show all original rules.

570

4. Check minimum number of events

None

570

5. Include endpoints

None

570

6. Filter based on genotype QC (FinnGen only)

570

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 570 262 308
Unadjusted period prevalence (%) 0.11 0.09 0.14
Median age at first event (years) 66.85 64.11 69.18

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
444
Matched controls
4438
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
JFB44
NOMESCO Finland
Laparoscopic left hemicolectomy
+∞
323.0
444
*
C18.71
ICD-10 Finland
Malignant tumor of the sigmoid invasive carcinoma
187.5
233.8
229
25
C18.70
ICD-10 Finland
Malignant tumor of the sigmoid without histology
173.5
190.9
190
19
8140/3-C18.7
ICD-O-3
Adenocarcinoma, NOS, of sigmoid colon
125.4
155.2
161
20
L01BC06
ATC
capecitabine; oral
23.5
95.1
141
86
UJF32
NOMESCO Finland
Coloscopy
8.3
91.6
299
881
B01AB05
ATC
enoxaparin; parenteral
7.2
80.1
304
1033
130
Kela drug reimbursment
Malignant tumour
10.7
74.6
160
221
WX302
NOMESCO Finland
Thoracal epidural anesthesy
16.5
74.1
125
103
C18.61
ICD-10 Finland
Malignant tumor of the colon descending invasive carcinoma
140.4
68.1
71
6
XF603
NOMESCO Finland
Direct intraarterial blood pressure measurement
17.6
62.8
102
74
JN4BD
NOMESCO Finland
Extensive body CT
7.8
61.6
164
311
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
9.1
59.7
139
212
TPH07
NOMESCO Finland
Cathetrisation of artery
7.4
55.9
153
296
WX402
NOMESCO Finland
General anaesthesia
6.4
55.9
177
418
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
10.8
55.3
114
138
A04AA02
ATC
granisetron; systemic, transdermal
9.1
48.9
111
157
C18.72
ICD-10 Finland
Malignant tumor of sigmoid carcinoma of adenoma
93.8
45.9
50
6
WZC30
NOMESCO Finland
Teaching
5.4
44.2
157
407
C18.79
ICD-10 Finland
Malignant tumor of the sigmoid or other unspecified histology
74.8
42.0
47
7
WX408
NOMESCO Finland
General anesthesy, balanced
4.2
41.7
219
834
C18.51
ICD-10 Finland
Malignant tumor of flexura hiealis invasive carcinoma
154.2
40.5
42
*
A03FA01
ATC
metoclopramide; systemic, rectal
4.3
38.2
182
622
C18.60
ICD-10 Finland
Malignant tumor of the descending colon without histology
207.2
37.4
38
*
C18.7
ICD-10 Finland
Malignant neoplasm: Sigmoid colon
87.8
36.5
40
5
H02AB02
ATC
dexamethasone; systemic
5.2
33.2
116
283
JFA98
NOMESCO Finland
Other transluminal endoscopic local operation on intestine
15.9
31.0
51
36
8140/3-C18.5
ICD-O-3
Adenocarcinoma, NOS, of splenic flexure of colon
+∞
30.6
29
*
C78.7
ICD-10 Finland
Secondary malignant neoplasm of liver and intrahepatic bile duct
15.0
30.4
51
38
8140/3-C18.6
ICD-O-3
Adenocarcinoma, NOS, of descending colon
166.2
30.1
31
*
C18.50
ICD-10 Finland
Malignant tumor in flexural lienalis without histology
311.3
29.1
29
*
WB113
NOMESCO Finland
Multiple adjuvant cytostatic therapy
7.2
28.7
73
118
R4110
NOMESCO Finland
Physiotherapy
3.3
27.9
187
798
8140/3-C18.9
ICD-O-3
Adenocarcinoma, NOS, of colon, NOS
49.0
26.9
32
7
D12.5
ICD-10 Finland
Benign neoplasm: Sigmoid colon
7.4
26.3
65
100
WX290
NOMESCO Finland
Other blockade of nerve
2.9
25.1
228
1179
JFB43
NOMESCO Finland
Left hemicolectomy
39.3
21.0
26
7
WD125
NOMESCO Finland
Demanding cystostatic therapy of methastized malignancy
5.7
20.5
61
120
D12.4
ICD-10 Finland
Benign neoplasm: Descending colon
12.5
20.1
36
31
WX404
NOMESCO Finland
Intravenous generell anesthesy
3.0
19.2
136
575
WD415
NOMESCO Finland
Demanding antibody therapy of methastized malignancy
11.8
17.0
31
28
Z08.0
ICD-10 Finland
Follow-up examination after surgery for malignant neoplasm
9.0
16.6
35
42
D37.4
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Colon
10.3
15.9
31
32
WX110
NOMESCO Finland
Local anesthesy
2.4
15.4
321
2328
A04AD12
ATC
aprepitant; systemic
8.5
14.3
31
39
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.6
14.1
123
575
UJF30
NOMESCO Finland
Ileoscopy through colon
3.4
13.7
69
225
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.0
13.1
53
144
C18.62
ICD-10 Finland
Malignant tumor of the descending colon carcinoma of the adenoma
51.6
12.9
15
*
1XC07
NOMESCO Finland
NA
51.6
12.9
15
*
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
4.2
12.0
46
119
C18.41
ICD-10 Finland
Malignant tumor of the transverse colon invasive carcinoma
48.0
11.9
14
*
D12.2
ICD-10 Finland
Benign neoplasm: Ascending colon
5.6
11.8
34
65
WB123
NOMESCO Finland
Demanding adjuvant cytostatic therapy
9.0
11.7
24
28
JJB10
NOMESCO Finland
Atypcal resection of liver
+∞
11.5
11
*
N02BE01
ATC
paracetamol; systemic, rectal
2.7
11.2
398
3386
E0000UV
ATC
NA
2.0
11.1
184
1143
WX002
NOMESCO Finland
Sedation and analgesia
2.3
10.9
117
599
8140/3-C19.9
ICD-O-3
Adenocarcinoma, NOS, of rectosigmoid junction
18.4
10.8
16
9
D75
ICPC
Malignant neoplasm colon/rectum
13.3
10.7
18
14
B01AB10
ATC
tinzaparin; parenteral
3.2
10.4
58
202
C79.8
ICD-10 Finland
Secondary malignant neoplasm of other specified sites
4.5
10.4
36
85
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
3.7
10.0
44
129
D12.0
ICD-10 Finland
Benign neoplasm: Caecum
6.2
10.0
26
44
ZX120
NOMESCO Finland
Intravenous
2.8
9.5
62
240
C18.59
ICD-10 Finland
Malignant tumor in flexura lienalis other or unspecified histology
+∞
9.4
9
*
Z93.3
ICD-10 Finland
Colostomy status
10.3
9.1
17
17
K57.2
ICD-10 Finland
Diverticular disease of large intestine with perforation and abscess
6.3
9.0
23
38
C18.69
ICD-10 Finland
Malignant tumor of colon descendens other or unspecified histology
51.0
8.7
10
*
K62.5
ICD-10 Finland
Haemorrhage of anus and rectum
3.5
8.5
39
119
WX306
NOMESCO Finland
Lumbar epidural anesthesy
3.7
8.4
36
104
JJB60
NOMESCO Finland
Other excsion of three or more segments of liver
+∞
8.4
8
*
D12.3
ICD-10 Finland
Benign neoplasm: Transverse colon
5.1
8.3
25
51
Z98.0
ICD-10 Finland
Intestinal bypass and anastomosis status
14.8
8.2
13
9
JN4AD
NOMESCO Finland
Body CT examination
2.8
8.2
54
209
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.6
8.2
62
265
A98
ICPC
Health maint/preventive medicine
3.2
7.9
425
3883
P01AB01
ATC
metronidazole; oral, rectal
1.8
7.8
181
1225
C18.40
ICD-10 Finland
Malignant tumor of the transverse colon without histology
15.4
7.8
12
8
JFB60
NOMESCO Finland
Resection of sigmoid colon with end colostomy
15.4
7.8
12
8
JJB71
NOMESCO Finland
Laparoscopic resection of liver
45.8
7.7
9
*
K92.1
ICD-10 Finland
Melaena
3.2
7.7
40
135
C18
ICD-10 Finland
Malignant neoplasm of colon
81.4
7.4
8
*
C18.5
ICD-10 Finland
Malignant neoplasm: Splenic flexure
81.4
7.4
8
*
D64.9
ICD-10 Finland
Anaemia, unspecified
2.5
7.3
59
259
L01BC59
ATC
trifluridine, combinations; systemic
30.5
7.2
9
*
C78.0
ICD-10 Finland
Secondary malignant neoplasm of lung
5.8
7.1
19
34
WD405
NOMESCO Finland
Simple antiboidy therapy of methastized malignancy
5.1
7.1
21
43
C19
ICD-10 Finland
Malignant neoplasm of rectosigmoid junction
9.5
6.8
13
14
WB103
NOMESCO Finland
Simple adjuvant cytostatic therapy
3.5
6.8
30
90
176
Kela drug reimbursment
Regorafenib
22.9
6.7
9
*
JN1CG
NOMESCO Finland
Extensive MRI examination of upper part of abdomen with high intensity magnet
4.9
6.6
20
42
QBB10
NOMESCO Finland
Major dressing of wound of skin of trunk
3.7
6.6
27
76
Z31.5
ICD-10 Finland
Genetic counselling
3.6
6.5
28
82
UJF34
NOMESCO Finland
Left colonoscopy
8.3
6.4
13
16
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.7
6.3
152
1024
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.2
6.3
62
300
JJB50
NOMESCO Finland
Excision of segments V, VI, VII and VIII of liver
+∞
6.3
6
*
C18.99
ICD-10 Finland
Malignant tumor in unspecified location in the colon other or unspecified histology
27.1
6.2
8
*
WX600
NOMESCO Finland
Single shot through catheter
7.8
6.2
13
17
Z71.8
ICD-10 Finland
Other specified counselling
1.8
6.1
107
652
JAH01
NOMESCO Finland
Laparoscopy
3.5
6.0
26
77

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: OPER_JFB44 – Laparoscopic left hemicolectomy

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).