Relapsing panniculitis [Weber-Christian]

M13_WEBERCHRISTIAN

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — M35.6 Cause of death: ICD-10 — M35.6 2 out of 7 registries used, show all original rules.	10
4. Check minimum number of events None	10
5. Include endpoints None	10
6. Filter based on genotype QC (FinnGen only)	10

Control definitions (FinnGen only)

Control exclude: M13_SYSTCONNECT

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: M35
Name in latin: Panniculitis recidiva (Weber-Christian)

NAME	M13_WEBERCHRISTIAN
CONTROL_EXCLUDE	M13_SYSTCONNECT
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M356
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	M356
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

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List of similar endpoints to Relapsing panniculitis [Weber-Christian] based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

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FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

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-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	87	59	28
Only index persons	77	52	25
Unadjusted period prevalence (%)
Whole population	0.00	0.00	0.00
Only index persons	0.00	0.00	0.00
Median age at first event (years)
Whole population	-	54.58	57.26
Only index persons	49.52	48.42	51.81

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	10	-	6
Unadjusted period prevalence (%)	0.00	-	0.00
Median age at first event (years)	52.16	-	55.77

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

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CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

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(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

unit

cases

controls

-log₁₀(p)

N cases

N controls

(1761868) Lipid panel - Serum or Plasma

3.30

0.92

4.4

2.5

—

(3013512) EKG study

3.13

0.90

4.8

4.3

—

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

0.00

0.23

0.0

4.1

—

30.8

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.00

0.23

0.0

1.2

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

0.00

0.22

0.0

2.2

—

7.4

—

(3031040) Bacteria [#/volume] in Urine by Automated count

1.49

0.13

2.8

3.5

—

(3029634) Reagin Ab [Titer] in Serum by VDRL

0.00

0.0

1.4

—

(3019060) Gas panel - Arterial blood

0.00

0.0

4.6

—

(4010399)

0.00

0.0

1.4

—

(4034850)

0.00

0.0

10.0

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

0.0

1.4

—

(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma

0.00

0.0

1.4

—

19.1

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

3.0

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.00

0.0

1.0

—

(3007778) Kappa light chains/Lambda light chains [Mass Ratio] in Serum

0.00

0.0

1.4

—

(3034860) Kappa light chains.free [Mass/volume] in Serum

0.00

0.0

1.4

—

32.5

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

0.00

0.0

2.3

—

(3002256) Pathology report gross observation

0.00

0.0

1.1

—

(3000494) Fungus identified in Specimen by Culture

0.00

0.0

1.7

—

(3004588) Protein electrophoresis panel - Serum or Plasma

0.00

0.0

1.8

—

(3019832) Treponema pallidum Ab [Presence] in Serum

0.00

0.0

1.4

—

(3037467) Urinalysis macro (dipstick) panel - Urine

1.17

0.00

4.4

3.7

—

(4035726)

0.00

0.0

1.1

—

(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma

0.00

0.0

1.7

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

1.08

0.00

3.8

2.2

—

(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction

0.00

-0.00

0.0

8.1

—

258.3

—

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.5

—

4.2

—

(3018677) aPTT in Platelet poor plasma by Coagulation assay

0.00

-0.00

0.0

2.0

—

27.6

—

(40768797) Stomach Pathology biopsy report

0.00

-0.00

0.0

1.1

—

(3020630) Protein [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.8

—

65.0

—

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

0.00

-0.00

0.0

2.4

—

Mortality – FinRegistry

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Association

Association between endpoint M13_WEBERCHRISTIAN and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have M13_WEBERCHRISTIAN.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

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Index endpoint: M13_WEBERCHRISTIAN – Relapsing panniculitis [Weber-Christian]

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Relapsing panniculitis [Weber-Christian]

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints