Calcium deposit in bursa

M13_CALCBURS

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M71.4
  • Cause of death: ICD-10 M71.4

2 out of 7 registries used, show all original rules.

74

4. Check minimum number of events

None

74

5. Include endpoints

None

74

6. Filter based on genotype QC (FinnGen only)

74

Control definitions (FinnGen only)

Control exclude
M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M71
Name in latin
Calcificatio bursae

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 441 216 224
Only index persons 420 209 211
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.01
Only index persons 0.01 0.01 0.01
Median age at first event (years)
Whole population 54.38 54.77 53.91
Only index persons 53.77 54.21 53.33

-FinnGen-

Key figures

All Female Male
Number of individuals 74 40 34
Unadjusted period prevalence (%) 0.01 0.01 0.01
Median age at first event (years) 52.16 49.86 54.86

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
62
Matched controls
618
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M71.4
ICD-10 Finland
Calcium deposit in bursa
+∞
89.0
62
*
NBG10
NOMESCO Finland
Acromioplastia
103.6
8.6
9
*
NHM20
NOMESCO Finland
Excision of synovial ganglion of ankle or foot
90.5
7.6
8
*
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
25.9
6.9
9
*
NCM20
NOMESCO Finland
Excision of synovial ganglion of elbow or forearm
+∞
6.3
6
*

Mortality – FinRegistry

Association

Association between endpoint M13_CALCBURS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have M13_CALCBURS.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: M13_CALCBURS – Calcium deposit in bursa

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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