Risteys · M13_CALCIFICTEND

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — M75.3 Hospital discharge: ICD-9 — 7261A Cause of death: ICD-10 — M75.3 Cause of death: ICD-9 — 7261A 2 out of 7 registries used, show all original rules.	2385
4. Check minimum number of events None	2385
5. Include endpoints None	2385
6. Filter based on genotype QC (FinnGen only)	2385

	All	Female	Male
Number of individuals
Whole population	13895	8889	4957
Only index persons	13375	8698	4677
Unadjusted period prevalence (%)
Whole population	0.21	0.25	0.14
Only index persons	0.27	0.32	0.18
Median age at first event (years)
Whole population	50.85	50.75	51.04
Only index persons	50.72	50.68	50.80

	All	Female	Male
Number of individuals	2385	1653	732
Unadjusted period prevalence (%)	0.49	0.56	0.32
Median age at first event (years)	50.92	50.24	52.46

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
2149: Matched controls
21490

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

NBG15

NOMESCO Finland

Acromioplastia, arthroscopic

120.8

323.0

719

M75.1

ICD-10 Finland

Rotator cuff syndrome

14.7

323.0

1182

1653

M75.3

ICD-10 Finland

Calcific tendinitis of shoulder

2913.1

323.0

1886

M75.4

ICD-10 Finland

Impingement syndrome of shoulder

38.1

323.0

501

170

7261A

ICD-9 Finland

Peripheral enthesopathies and allied syndromes, Rotator cuff syndrome of shoulder and allied disorders[TENDINITIS CALCIFICANS HUMEROSCAPULARIS]

+∞

289.2

271

NBF25

NOMESCO Finland

Operation for humeroscapular osteochondritis, arthroscopic

51.1

212.6

257

9242

FHL

Other reconstruction or plastic surgery of shoulder joint (including ac joint)

101.8

185.9

203

M75.0

ICD-10 Finland

Adhesive capsulitis of shoulder

14.8

172.8

301

234

NBG10

NOMESCO Finland

Acromioplastia

91.4

166.3

184

N02AX02

ATC

tramadol; systemic, rectal

3.6

165.0

1134

5090

NBA30

NOMESCO Finland

Exploration of joint of shoulder or upper arm, arthroscopic

44.9

161.4

200

L08

ICPC

Shoulder symptom/complaint

4.6

153.8

636

1799

M01AH05

ATC

etoricoxib; oral

3.5

151.8

1575

9435

N02AA59

ATC

codeine, combinations excl. psycholeptics; systemic

3.1

135.1

1207

6241

N03AX12

ATC

gabapentin; oral

4.8

126.4

483

1230

M79.6

ICD-10 Finland

Pain in limb

3.4

126.1

811

3265

M19.0

ICD-10 Finland

Primary arthrosis of other joints

6.1

116.0

347

662

N03AX16

ATC

pregabalin; oral

3.6

115.6

647

2309

NB1AE

NOMESCO Finland

Shoulder ultrasound examination

24.8

108.4

155

NB1ZT

NOMESCO Finland

Crushing of soft tissue calcifications in shoulder wiht ultrasound quidance

+∞

104.0

NB1AA

NOMESCO Finland

Shoulder X-ray examination without contrast

7.7

101.7

251

364

M03BX02

ATC

tizanidine; oral

2.7

98.3

1542

10357

M01AC06

ATC

meloxicam; systemic, rectal

2.6

91.0

965

5100

M25.5

ICD-10 Finland

Pain in joint

2.9

90.1

731

3285

M54.5

ICD-10 Finland

Low back pain

2.7

89.8

804

3840

NBT60

NOMESCO Finland

Forcible manipulation of humeroscapular joint

92.3

87.8

NBG00

NOMESCO Finland

Plastic operation on acromioclavicular joint

49.6

85.8

104

M54.4

ICD-10 Finland

Lumbago with sciatica

3.4

80.6

448

1531

SPAT1223

SPAT

Implementation of physical therapy rehabilitation plan

2.7

80.6

699

3230

M51.1

ICD-10 Finland

Lumbar and other intervertebral disc disorders with radiculopathy

3.6

79.3

409

1317

N02BE01

ATC

paracetamol; systemic, rectal

3.2

78.9

1907

15279

M01AB05

ATC

diclofenac; systemic, rectal

2.5

77.8

1562

11158

G56.0

ICD-10 Finland

Carpal tunnel syndrome

3.7

77.6

389

1222

M79.0

ICD-10 Finland

Rheumatism, unspecified

25.4

77.1

109

N02AJ06

ATC

codeine and paracetamol; systemic

2.4

75.7

883

4774

N02AE01

ATC

buprenorphine; parenteral, sublingual, transdermal

4.5

72.4

282

703

NDM40

NOMESCO Finland

Discission of sheath of tendon of wrist or hand

91.1

71.4

A02BC02

ATC

pantoprazole; systemic

2.3

71.3

1459

10261

M75.2

ICD-10 Finland

Bicipital tendinitis

14.5

69.8

120

M70.6

ICD-10 Finland

Trochanteric bursitis

3.8

67.5

321

957

SPAT1153

SPAT

Removal of sutures

2.4

67.4

750

3898

M01AH01

ATC

celecoxib; oral (coxibs)

2.9

65.0

478

1956

M01AX17

ATC

nimesulide; oral

2.5

63.0

601

2857

M51.3

ICD-10 Finland

Other specified intervertebral disc degeneration

4.5

62.0

238

581

M02AA07

ATC

piroxicam; topical

2.2

61.6

849

4847

NB1BG

NOMESCO Finland

Shoulder and humerus MRI examination with high intensity magnet

18.6

61.5

A02BC03

ATC

lansoprazole; oral

2.4

60.9

702

3672

M65.3

ICD-10 Finland

Trigger finger

10.8

59.8

118

115

7261X

ICD-9 Finland

Peripheral enthesopathies and allied syndromes, Rotator cuff syndrome of shoulder and allied disorders[MUU TAI TARKEMMIN MÄÄRITTELEM KIERTÄJÄKALVOSINSDR]

+∞

57.5

M01AE03

ATC

ketoprofen; systemic, rectal

2.2

57.0

866

5116

M77.1

ICD-10 Finland

Lateral epicondylitis

4.5

57.0

219

534

WX200

NOMESCO Finland

Interscalenous plexus blockade

14.4

57.0

M03BC01

ATC

orphenadrine (citrate); systemic

2.4

56.3

593

2942

M01AE02

ATC

naproxen; oral, rectal

2.1

56.2

1262

8763

M47.2

ICD-10 Finland

Other spondylosis with radiculopathy

5.0

55.3

188

403

A02BC05

ATC

esomeprazole; systemic

2.1

54.2

944

5872

NA3BG

NOMESCO Finland

Lumbar spine MRI examination with high intensity magnet

3.8

53.8

248

714

NB1CG

NOMESCO Finland

Shoulder and humerus extensive MRI examination with high intensity magnet

18.7

53.5

R03AC02

ATC

salbutamol; inhalant

2.0

52.6

1163

7932

M53.1

ICD-10 Finland

Cervicobrachial syndrome

3.2

52.6

310

1080

R10.4

ICD-10 Finland

Other and unspecified abdominal pain

2.2

52.4

751

4281

H02AB06

ATC

prednisolone; systemic

2.0

51.1

1013

6588

NB1BA

NOMESCO Finland

Shoulder extensive X-ray examination without contrast

8.3

50.7

116

147

SPAT1263

SPAT

Sampling

2.0

50.6

898

5581

N06AA09

ATC

amitriptyline; systemic

3.5

49.4

256

808

M79.7

ICD-10 Finland

Fibromyalgia

10.9

49.1

M65.2

ICD-10 Finland

Calcific tendinitis

70.4

48.3

NBL22

NOMESCO Finland

Myotomy, tenotomy or excision of tendon of upper arm

31.9

46.9

M01AE01

ATC

ibuprofen; systemic, rectal

2.8

46.5

1971

17173

R51.80

ICD-10 Finland

Headache

2.8

46.2

335

1330

NBL00

NOMESCO Finland

Suture or reinsertation of rotator cuff of shoulder

6.5

45.1

121

194

M48.0

ICD-10 Finland

Spinal stenosis

3.3

44.5

250

836

SPAT1301

SPAT

No procedures

2.1

43.8

649

3693

L03

ICPC

Low back symptom/complaint

2.2

43.1

507

2602

N06AX21

ATC

duloxetine; oral

3.1

42.9

264

941

G44.2

ICD-10 Finland

Tension-type headache

2.7

42.5

320

1295

SPAT1310

SPAT

Counselling related to known health issue

2.0

41.8

677

3979

SPAT1249

SPAT

Treatment-related counselling outside office

1.9

41.3

823

5232

M01AH02

ATC

rofecoxib; oral

2.7

41.2

307

1236

NB2AT

NOMESCO Finland

Intra artrial injection of shoulder with ultrasound guidance

19.9

41.1

M67.4

ICD-10 Finland

Ganglion

5.4

39.8

124

240

UJD10

NOMESCO Finland

Esophagoscopy, gastroscopy and duodenoscopy

2.1

39.7

592

3348

L92

ICPC

Shoulder syndrome

9.1

39.1

NA1BG

NOMESCO Finland

Cervical spine MRI examination with high intensity magnet

4.7

39.1

138

307

M17.1

ICD-10 Finland

Other primary gonarthrosis

2.3

39.1

436

2171

Z01.8

ICD-10 Finland

Other specified special examinations

2.2

38.9

468

2412

SPAT1253

SPAT

Initiation, adjustment, discontinuation or repetition of medication

2.0

38.9

611

3527

J01DB01

ATC

cefalexin; oral

2.0

37.8

1724

14403

ZXA00

NOMESCO Finland

Right side

2.1

37.6

552

3093

J01AA02

ATC

doxycycline; systemic

2.0

37.6

1706

14205

M50.1

ICD-10 Finland

Cervical disc disorder with radiculopathy

4.7

37.0

130

288

M75.9

ICD-10 Finland

Shoulder lesion, unspecified

5.1

36.7

120

246

NDM20

NOMESCO Finland

Excision of synovial ganglion of wrist or hand

26.9

36.4

A02BC01

ATC

omeprazole; systemic

2.0

36.3

566

3240

SPAT1203

SPAT

Injection therapy, other than intramuscular or subcutaneous

4.7

35.9

126

279

R07.4

ICD-10 Finland

Chest pain, unspecified

2.0

35.2

524

2940

ACC59

NOMESCO Finland

Decompression and freeing of adhesions of peripheral nerve: other or unspecified

4.3

34.8

133

321

J01.0

ICD-10 Finland

Acute maxillary sinusitis

2.1

34.6

481

2623

G54.0

ICD-10 Finland

Brachial plexus disorders

7.1

34.3

126

S18

ICPC

Laceration/cut

1.8

33.9

810

5381

M03BA52

ATC

carisoprodol, combinations excl. psycholeptics; oral

5.6

33.9

102

190

NB1AT

NOMESCO Finland

Puncture of shoulder with ultrasound guidance

25.2

33.7

M03BC51

ATC

orphenadrine, combinations; systemic

1.9

33.6

642

3950

NAG40

NOMESCO Finland

Anterior fusion of cervical spine without fixation

6.7

33.2

132

M01AX05

ATC

glucosamine; oral

2.2

33.1

396

2018

L01

ICPC

Neck symptom/complaint

2.5

33.0

298

1324

M79.1

ICD-10 Finland

Myalgia

2.7

32.9

238

934

NBL50

NOMESCO Finland

Tenolysis or tenosynovectomy of shoulder or upper arm

172.6

32.8

R10.3

ICD-10 Finland

Pain localized to other parts of lower abdomen

2.1

32.7

448

2420

ACC51

NOMESCO Finland

Release of median nerve

3.2

32.5

185

621

M75.5

ICD-10 Finland

Bursitis of shoulder

7.6

32.4

104

M54.2

ICD-10 Finland

Cervicalgia

3.3

32.2

174

563

UJF32

NOMESCO Finland

Coloscopy

2.0

31.2

513

2973

R06.0

ICD-10 Finland

Dyspnoea

2.0

30.8

454

2518

ZXA05

NOMESCO Finland

Left side

2.0

30.5

495

2848

SPAT1230

SPAT

Aid fitting and borrowing and monitoring of use

2.2

30.0

327

1594

M23.2

ICD-10 Finland

Derangement of meniscus due to old tear or injury

2.5

29.7

254

1094

M54.9

ICD-10 Finland

Dorsalgia, unspecified

2.7

29.5

223

898

SPAT1260

SPAT

Consultation of another employee

2.1

29.3

360

1850

SPAT1256

SPAT

Intramuscular and subcutaneous injection

1.7

29.2

824

5691

M75.8

ICD-10 Finland

Other shoulder lesions

5.4

28.7

172

M47.80

ICD-10 Finland

Other spondylosis, multiple sites in spine

5.8

28.6

148

M72.2

ICD-10 Finland

Plantar fascial fibromatosis

3.1

27.8

164

563

J01FF01

ATC

clindamycin; systemic

1.8

27.7

555

3428

M01AB55

ATC

diclofenac, combinations; oral

3.1

27.6

157

526

M02AA10

ATC

ketoprofen; topical

2.1

27.3

338

1739

NA3AA

NOMESCO Finland

Lumbar spine X-ray examination without contrast

2.8

27.1

186

703

AA1AD

NOMESCO Finland

CT of head and brain

2.0

27.1

431

2447

J01FA10

ATC

azithromycin; systemic

1.6

27.0

1227

9611

M01AB08

ATC

etodolac; oral

2.8

26.9

183

690

EB1AA

NOMESCO Finland

Tooth X-ray examination

1.6

26.9

1153

8888

N06CA01

ATC

amitriptyline and psycholeptics; systemic

2.5

26.9

230

988

N06AX11

ATC

mirtazapine; oral

1.8

26.7

647

4238

F45.4

ICD-10 Finland

Persistent somatoform pain disorder

10.6

26.3

R10.1

ICD-10 Finland

Pain localized to upper abdomen

2.1

26.2

334

1734

SPAT1312

SPAT

General health counselling

1.8

26.1

607

3922

S46.0

ICD-10 Finland

Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder

3.2

26.1

147

488

M47.82

ICD-10 Finland

Other spondylosis, cervical region

4.4

26.1

233

M50.3

ICD-10 Finland

Other cervical disc degeneration

6.4

26.0

110

R29.8

ICD-10 Finland

Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems

2.7

25.4

185

726

M15.9

ICD-10 Finland

Polyarthrosis, unspecified

3.4

25.4

127

387

J01FA06

ATC

roxithromycin; oral

1.7

25.1

835

5969

J45.9

ICD-10 Finland

Asthma, unspecified

2.1

25.1

336

1778

P01AB01

ATC

metronidazole; oral, rectal

1.6

25.1

847

6084

M54.3

ICD-10 Finland

Sciatica

3.3

25.0

132

420

C10AA05

ATC

atorvastatin; oral

1.7

24.9

707

4837

C01DA08

ATC

isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal

2.0

24.6

356

1944

GD1AA

NOMESCO Finland

Thorax X-ray examination

1.7

24.5

787

5566

TNX10

NOMESCO Finland

Arthrocentesis, unspecified region, unspecified region

3.1

24.5

144

492

PH2AE

NOMESCO Finland

Ultrasound examination of lower leg veins

2.6

24.4

195

807

7890A

ICD-9 Finland

Other symptoms involving abdomen and pelvis, Abdominal pain

3.1

24.4

138

460

SAA01

NOMESCO Finland

Simple examination of mouth

1.6

24.3

1440

11932

J06.9

ICD-10 Finland

Acute upper respiratory infection, unspecified

1.6

24.2

838

6043

A06AC01

ATC

ispaghula (psylla seeds); oral

1.8

23.8

477

2921

M47.9

ICD-10 Finland

Spondylosis, unspecified

5.0

23.8

157

M25.2

ICD-10 Finland

Flail joint

11.5

23.7

M77.0

ICD-10 Finland

Medial epicondylitis

6.1

23.7

109

N02AC04

ATC

dextropropoxyphene; oral

4.2

23.5

228

ZXE10

NOMESCO Finland

More than one and less than three hours

1.7

23.4

727

5074

X59

ICD-10 Finland

Exposure to unspecified factor

2.0

23.2

334

1818

R52.2

ICD-10 Finland

Other chronic pain

4.8

22.9

168

SPAT1250

SPAT

Comprehensive monitoring of chronic illness

1.8

22.6

493

3100

M65.4

ICD-10 Finland

Radial styloid tenosynovitis [de Quervain]

6.6

22.4

G56.2

ICD-10 Finland

Lesion of ulnar nerve

4.5

22.1

179

A01

ICPC

Pain general/multiple sites

2.9

22.1

142

516

J01CA04

ATC

amoxicillin; systemic

1.7

22.0

1642

14226

NGF25

NOMESCO Finland

Operation for osteochondritis of knee, arthroscopic

2.8

22.0

145

535

WZB00

NOMESCO Finland

Telephone receipt or other advice

1.7

22.0

560

3684

G47.3

ICD-10 Finland

Sleep apnoea

1.8

21.8

416

2497

M01AC01

ATC

piroxicam; systemic, rectal

2.1

21.7

280

1453

1220

FHL

Arthroscopy

3.8

21.7

261

M75

ICD-10 Finland

Shoulder lesions

3.4

21.5

108

331

WX702

NOMESCO Finland

Supraglottic ventilation device

3.0

21.5

131

461

C07AB07

ATC

bisoprolol; oral

1.6

21.4

817

5983

M54.1

ICD-10 Finland

Radiculopathy

3.8

21.3

245

R06AE07

ATC

cetirizine; oral

1.6

21.2

889

6664

J01FA09

ATC

clarithromycin; systemic

1.6

21.1

655

4547

SFA10

NOMESCO Finland

Fillning on one surface of tooth

1.5

21.0

1052

8220

NCL22

NOMESCO Finland

Myotomy or tenotomy of elbow or forearm

+∞

20.9

C10AA07

ATC

rosuvastatin; oral

1.7

20.8

471

2981

L17

ICPC

Foot/toe symptom/complaint

1.8

20.8

450

2811

J20.9

ICD-10 Finland

Acute bronchitis, unspecified

1.9

20.6

323

1809

Z01.0

ICD-10 Finland

Examination of eyes and vision

1.9

20.6

314

1741

N06AX16

ATC

venlafaxine; oral

2.0

20.6

295

1596

M67.8

ICD-10 Finland

Other specified disorders of synovium and tendon

30.3

20.6

SAA02

NOMESCO Finland

Basic examination of mouth

1.5

20.5

1276

10457

J02AC01

ATC

fluconazole; systemic

1.6

20.3

866

6492

WYA05

NOMESCO Finland

Emergency visit or other similar visit involving procedures

1.5

20.2

963

7408

NBL05

NOMESCO Finland

Arthroscopic suture or reinsertation of rotator cuff of shoulder

11.7

20.2

L86

ICPC

Back syndrome with radiating pain

3.0

20.1

120

416

L13

ICPC

Hip symptom/complaint

2.0

20.0

283

1521

J01CR02

ATC

amoxicillin and beta-lactamase inhibitor; systemic

1.5

20.0

1002

7794

WX110

NOMESCO Finland

Local anesthesy

1.5

20.0

1370

11448

R03DC03

ATC

montelukast; oral

1.9

19.9

331

1891

R01BA52

ATC

pseudoephedrine, combinations; oral

1.6

19.7

687

4894

M19.9

ICD-10 Finland

Arthrosis, unspecified

3.7

19.6

242

S01XA20

ATC

artificial tears and other indifferent preparations; ophthalmic

1.6

19.6

801

5931

NDM10

NOMESCO Finland

Palmar fasciotomy of hand

40.5

19.5

M54.6

ICD-10 Finland

Pain in thoracic spine

2.7

19.5

138

532

M76.6

ICD-10 Finland

Achilles tendinitis

3.7

19.4

239

ND2AA

NOMESCO Finland

Hand and fingers X-ray examination

2.4

19.1

163

699

M01AH03

ATC

valdecoxib; oral

2.6

19.0

144

580

C10AX09

ATC

ezetimibe; oral

2.2

18.8

211

1032

FN1AC

NOMESCO Finland

Angiography of heart and/or coronary arteries

1.8

18.8

348

2062

SPAT1028

SPAT

Ultrasound examination of paranasal sinuses

2.7

18.4

132

514

H02AB04

ATC

methylprednisolone; systemic

1.9

18.3

285

1587

N02AA05

ATC

oxycodone; systemic

2.1

18.2

232

1195

9253

FHL

Manipulation under anesthesia or regression and plastering

21.9

18.2

M72.0

ICD-10 Finland

Palmar fascial fibromatosis [Dupuytren]

9.4

18.1

J01EE02

ATC

sulfadiazine and trimethoprim; systemic

1.7

17.9

475

3131

R42

ICD-10 Finland

Dizziness and giddiness

1.8

17.8

370

2269

Z01.5

ICD-10 Finland

Diagnostic skin and sensitization tests

2.1

17.8

201

984

NA3CG

NOMESCO Finland

Lumbar spine extensive MRI examination with high intensity magnet

3.6

17.8

236

K21.0

ICD-10 Finland

Gastro-oesophageal reflux disease with oesophagitis

2.2

17.8

194

935

ABC36

NOMESCO Finland

Decompression of lumbar nerve roots

3.1

17.7

318

B01AC04

ATC

clopidogrel; oral

2.0

17.7

240

1269

NB1DG

NOMESCO Finland

Shoulder and humerus very extensive MRI examination with high intensity magnet

14.7

17.6

WX408

NOMESCO Finland

General anesthesy, balanced

1.6

17.5

494

3312

NGD05

NOMESCO Finland

Partial excision of meniscus of knee, arthroscopic

2.0

17.5

229

1193

215

Kela drug reimbursment

Diabetes, non-insulin-treated

1.7

17.5

436

2824

SPAT1202

SPAT

Intra-articular injection

4.1

17.5

174

SPAT1216

SPAT

Assessment of functional ability

2.0

17.3

247

1329

203

Kela drug reimbursment

Chronic asthma and similar chronic obstructive pulmonary diseases

1.8

17.3

351

2138

R03AK07

ATC

formoterol and budesonide; inhalant

1.7

17.3

378

2358

K21.9

ICD-10 Finland

Gastro-oesophageal reflux disease without oesophagitis

2.2

17.2

186

895

M13.9

ICD-10 Finland

Arthritis, unspecified

2.5

17.1

137

567

J01MA02

ATC

ciprofloxacin; systemic

1.5

17.0

698

5125

M77.4

ICD-10 Finland

Metatarsalgia

3.0

17.0

333

1225

FHL

Arthroscopy and other therapeutic procedure

5.7

16.9

R03BA01

ATC

beclometasone; inhalant

1.9

16.8

282

1613

R05

ICD-10 Finland

Cough

1.7

16.8

358

2212

R01AD58

ATC

fluticasone, combinations; inhalant, nasal

1.7

16.7

420

2723

7260A

ICD-9 Finland

Peripheral enthesopathies and allied syndromes, Adhesive capsulitis of shoulder

+∞

16.7

R20.2

ICD-10 Finland

Paraesthesia of skin

2.5

16.7

135

563

R52.9

ICD-10 Finland

Pain, unspecified

2.4

16.7

150

662

NGA30

NOMESCO Finland

Exploration of knee joint, arthroscopic

2.8

16.6

107

391

ABC26

NOMESCO Finland

Open discectomy of lumbar spine

5.0

16.6

108

K02.1

ICD-10 Finland

Caries of dentine

1.5

16.5

1096

8914

NCL99

NOMESCO Finland

Other operation on muscle or tendon of elbow or forearm

171.2

16.5

SPAT1324

SPAT

Screening procedure

1.6

16.4

453

3015

ZXD20

NOMESCO Finland

Day surgery

1.9

16.4

257

1435

WX704

NOMESCO Finland

Intubation

2.3

16.4

151

675

R01AD09

ATC

mometasone; nasal

1.5

16.3

898

7022

G03CA03

ATC

estradiol; nasal, systemic, rectal, transdermal, vaginal

1.5

16.2

950

7517

FM1EE

NOMESCO Finland

Extensive structural and functional ultrasound examination of heart

1.7

16.0

357

2233

SFA20

NOMESCO Finland

Filling on two surfaces of tooth

1.5

16.0

1144

9419

NA3EA

NOMESCO Finland

Lumbar spine X-ray examination with flexion

3.9

16.0

169

M19.8

ICD-10 Finland

Other specified arthrosis

3.4

15.9

231

103

Kela drug reimbursment

Diabetes, insulin-treated

1.6

15.9

449

3004

R03BA05

ATC

fluticasone; inhalant

1.7

15.8

335

2063

M53.0

ICD-10 Finland

Cervicocranial syndrome

2.2

15.8

171

820

SPAT1283

SPAT

Restricted health certificate

1.8

15.8

314

1896

NHL16

NOMESCO Finland

Tenolysis or tenosynovectomy of achilles tendon

60.4

15.8

N02CC01

ATC

sumatriptan; nasal, systemic, rectal

1.8

15.7

272

1570

M79.2

ICD-10 Finland

Neuralgia and neuritis, unspecified

5.9

15.6

ICD-10 Finland

4.0

15.3

156

NA1AA

NOMESCO Finland

Cervical spine X-ray examination without contrast

3.7

15.3

181

SPAT1033

SPAT

Irrigation or wax removal of outer auditory canal

1.7

15.2

325

2004

S43.4

ICD-10 Finland

Sprain and strain of shoulder joint

3.4

15.1

214

M70.7

ICD-10 Finland

Other bursitis of hip

4.7

15.1

111

SPAT1254

SPAT

Administration of medicine

1.9

15.0

227

1248

J01DA01

ATC

[U] cefalexin; systemic

1.4

15.0

1245

10497

A02BA02

ATC

ranitidine; systemic

1.7

14.9

344

2168

C10AA01

ATC

simvastatin; oral

1.5

14.9

703

5293

WZC00

NOMESCO Finland

Planning of intervention or health care consultation

1.5

14.8

621

4554

SPAT1295

SPAT

Other function in accordance with physical therapy nomenclature

2.6

14.8

107

418

N05CF02

ATC

zolpidem; oral

1.7

14.8

360

2306

N04BC05

ATC

pramipexole; oral

2.4

14.8

132

581

Z50.9

ICD-10 Finland

Care involving use of rehabilitation procedure, unspecified

3.0

14.7

284

Z50.1

ICD-10 Finland

Other physical therapy

2.7

14.7

373

C01DA14

ATC

isosorbide mononitrate; oral

2.0

14.7

185

949

SPAT1058

SPAT

PEF monitoring instruction

2.2

14.7

154

731

M01AC02

ATC

tenoxicam; systemic, rectal

2.7

14.7

102

390

SPAT1262

SPAT

Handing over of treatment supplies

1.7

14.6

313

1932

73109

ICD-8 Finland

Synovitis, bursitis and tenosynovitis, Unspecified

+∞

14.6

EB1SA

NOMESCO Finland

Dental X-ray, bite-wing X-ray on one side of the mouth

1.4

14.5

956

7688

M65.9

ICD-10 Finland

Synovitis and tenosynovitis, unspecified

5.0

14.5

R74

ICPC

Upper respiratory infection acute

1.6

14.4

492

3436

SFC01

NOMESCO Finland

Adjuvant procedure of filling therapy

1.5

14.4

522

3700

SPAT1325

SPAT

Vaccination

1.5

14.3

573

4157

R11

ICD-10 Finland

Nausea and vomiting

2.3

14.2

133

599

Z00.0

ICD-10 Finland

General medical examination

1.7

14.1

313

1948

T90

ICPC

Diabetes non-insulin dependent

1.6

14.1

385

2541

R01AD12

ATC

fluticasone furoate; nasal

1.5

14.0

584

4266

1412

FHL

Laparoscopy and sterilization

2.1

14.0

163

806

WX290

NOMESCO Finland

Other blockade of nerve

1.4

14.0

827

6496

M77.9

ICD-10 Finland

Enthesopathy, unspecified

3.6

14.0

174

T81.4

ICD-10 Finland

Infection following a procedure, not elsewhere classified

2.0

14.0

198

1061

L12

ICPC

Hand/finger symptom/complaint

1.8

13.8

229

1302

M23.9

ICD-10 Finland

Internal derangement of knee, unspecified

2.1

13.7

157

775

SPAT1212

SPAT

Extensive examination of musculoskeletal system

2.2

13.7

142

669

M17.9

ICD-10 Finland

Gonarthrosis, unspecified

2.0

13.7

186

984

M01AE52

ATC

naproxen and esomeprazole; oral

3.0

13.6

277

A02BC04

ATC

rabeprazole; oral

2.0

13.6

177

921

J05AB01

ATC

aciclovir; systemic

1.6

13.5

398

2675

R05

ICPC

Cough

1.6

13.5

388

2595

Z87.1

ICD-10 Finland

Personal history of diseases of the digestive system

1.4

13.5

883

7059

NBE35

NOMESCO Finland

Transposition of ligament of shoulder, arthroscopic

10.1

13.5

L15

ICPC

Knee symptom/complaint

1.6

13.4

348

2264

M17

ICD-10 Finland

Gonarthrosis [arthrosis of knee]

1.9

13.4

190

1019

C01DA02

ATC

glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal

1.8

13.4

246

1445

F32.2

ICD-10 Finland

Severe depressive episode without psychotic symptoms

2.4

13.3

117

510

M76.8

ICD-10 Finland

Other enthesopathies of lower limb, excluding foot

6.2

13.3

SPAT1081

SPAT

Cardiorespiratory global assessment

2.5

13.3

105

434

AN1

Coronary angiography

2.0

13.3

173

901

SPAT1156

SPAT

Guidance concerning treatment of rash and skin

1.9

13.3

217

1228

SPAT1097

SPAT

Recording of ECG

1.8

13.1

247

1462

V252A

ICD-9 Finland

Contraceptive management, Sterilisation

1.9

12.9

199

1099

A10BA02

ATC

metformin; oral

1.5

12.9

455

3196

ZXE00

NOMESCO Finland

One hour or less

1.4

12.9

715

5521

N05CF01

ATC

zopiclone; oral

1.5

12.9

574

4243

-1

NOMESCO Finland

1.5

12.9

600

4477

E11.9

ICD-10 Finland

Type 2 diabetes mellitus, without complications

1.6

12.8

356

2356

Z50.8

ICD-10 Finland

Care involving use of other rehabilitation procedures

2.2

12.7

124

570

A02BA04

ATC

nizatidine; systemic

2.2

12.7

136

652

SFA30

NOMESCO Finland

Filling on tree or more surfaces of tooth

1.4

12.7

813

6450

K58.0

ICD-10 Finland

Irritable bowel syndrome with diarrhoea

2.5

12.7

101

420

WX725

NOMESCO Finland

Noninvasive ventilation

2.5

12.7

393

R96

ICPC

Asthma

2.1

12.6

153

772

E66.01

ICD-10 Finland

Obesity due to excess calories

2.1

12.6

139

673

G55.1*M51.1

ICD-10 Finland

Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions

3.6

12.6

159

I25.1

ICD-10 Finland

Atherosclerotic heart disease

1.7

12.5

281

1754

NA1EA

NOMESCO Finland

Cervical spine X-ray examination with flexion

5.5

12.5

M89.0

ICD-10 Finland

Algoneurodystrophy

11.1

12.5

R03BA08

ATC

ciclesonide; inhalant

2.0

12.5

161

834

EB1HA

NOMESCO Finland

Panorama tomography of teeth and jaws or similar X-ray examination

1.4

12.5

711

5510

SAA03

NOMESCO Finland

Extended examination of mouth

1.4

12.5

700

5410

A09

ICD-10 Finland

Other gastroenteritis and colitis of infectious and unspecified origin

1.7

12.5

253

1534

NHM10

NOMESCO Finland

Fasciotomy of ankle or foot

130.7

12.4

M18.1

ICD-10 Finland

Other primary arthrosis of first carpometacarpal joint

4.6

12.4

N05BA01

ATC

diazepam; systemic, rectal

1.8

12.3

235

1397

J45.0

ICD-10 Finland

Predominantly allergic asthma

2.1

12.3

147

739

J01DA09

ATC

[U] cefadroxil; inhalant, oral

1.5

12.3

519

3785

NG1AA

NOMESCO Finland

Knee X-ray examination without contrast

1.9

12.3

189

1046

SPAT1210

SPAT

Application of cast or individual aid

2.6

12.3

358

S06.0

ICD-10 Finland

Concussion

2.0

12.3

163

853

R13

ICD-10 Finland

Dysphagia

2.3

12.3

111

493

NA1CG

NOMESCO Finland

Cervical spine extensive MRI examination with high intensity magnet

4.3

12.3

103

SHA03

NOMESCO Finland

Correction of physiology of bite - demanding therapy visit

3.2

12.2

200

M19.1

ICD-10 Finland

Post-traumatic arthrosis of other joints

3.8

12.2

137

G43.1

ICD-10 Finland

Migraine with aura [classical migraine]

2.2

12.2

118

541

M23.8

ICD-10 Finland

Other internal derangements of knee

2.9

12.0

263

SHA01

NOMESCO Finland

Correction of physiology of bite - simple therapy visit

1.8

12.0

203

1162

K30

ICD-10 Finland

Functional dyspepsia

1.9

12.0

186

1031

ABD30

NOMESCO Finland

Implantation of spinal stimulation device

9.3

12.0

R06.5

ICD-10 Finland

Mouth breathing

2.0

12.0

153

791

NB1AE

SPAT

3.8

11.9

130

X58

ICD-10 Finland

Exposure to other specified factors

1.8

11.9

216

1263

TPH04

NOMESCO Finland

Cathetrisation of vein

1.6

11.9

347

2323

H03AA01

ATC

levothyroxine sodium; systemic

1.5

11.9

453

3229

RF210

NOMESCO Finland

3.2

11.9

199

Z3226

NOMESCO Finland

Physiotherapist

1.6

11.8

306

1986

NGF00

NOMESCO Finland

Excision of plica of synovy of knee

3.8

11.6

128

SPAT1306

SPAT

Counselling and guidance related to nutrition and weight management

1.7

11.6

227

1361

M01AE51

ATC

ibuprofen, combinations; systemic

4.9

11.6

J22

ICD-10 Finland

Unspecified acute lower respiratory infection

2.5

11.5

378

M17.0

ICD-10 Finland

Primary gonarthrosis, bilateral

1.8

11.5

219

1300

NK4XE

NOMESCO Finland

Joint ultrasound examination not elsewhere classified

2.2

11.5

115

535

SPAT1144

SPAT

Treatment of reopened or infected surgical wound

2.1

11.5

125

605

SHB00

NOMESCO Finland

Prepation and fitting of bite rail to mouth

1.9

11.5

171

937

2402

FHL

External neurolysis of the nerve and possible alteration of the pathway (nerve pressure)

5.7

11.5

R53

ICD-10 Finland

Malaise and fatigue

1.6

11.5

319

2109

73398

ICD-8 Finland

Other diseases of muscle, tendon and fascia, Alii definiti

+∞

11.5

73101

ICD-8 Finland

Tendinivaginitis chronica, inflammation of the synovial membrane, bursa and tendon sheath

+∞

11.5

7263A

ICD-9 Finland

Peripheral enthesopathies and allied syndromes, Enthesopathy of elbow region[EPICONDYLITIS LATERALIS HUMERI]

+∞

11.5

7290A

ICD-9 Finland

Other disorders of soft tissues, Rheumatism, unspecified and fibrositis

+∞

11.5

R05FA02

ATC

opium derivatives and expectorants; systemic

1.4

11.4

764

6079

WZA90

NOMESCO Finland

Other doctors statement

1.5

11.4

392

2728

J34.2

ICD-10 Finland

Deviated nasal septum

2.4

11.4

431

P01BA02

ATC

hydroxychloroquine; oral

2.0

11.4

146

755

R03AC03

ATC

terbutaline; inhalant

1.7

11.4

249

1542

XPX99

NOMESCO Finland

Other diagnostic examination of periferal vessel

2.4

11.3

394

SPAT1211

SPAT

Application of soft bandage

2.0

11.3

148

773

M15.0

ICD-10 Finland

Primary generalized (osteo)arthrosis

3.2

11.3

179

R03BA02

ATC

budesonide; inhalant

1.6

11.3

310

2043

G56.4

ICD-10 Finland

Causalgia

25.1

11.1

SPAT1148

SPAT

Treatment of chronic ulcer or burn

1.8

11.1

199

1160

C07AB02

ATC

metoprolol; systemic

1.6

11.1

321

2144

Z30.2

ICD-10 Finland

Sterilization

1.7

11.1

245

1523

H04.10

ICD-10 Finland

Dry eye syndrome

1.8

11.0

182

1033

C03EA01

ATC

hydrochlorothiazide and potassium-sparing agents; oral

1.7

11.0

249

1557

R05FB02

ATC

cough suppressants and expectorants

1.4

11.0

713

5630

NBE45

NOMESCO Finland

Plastic repair of ligament of shoulder not using prosthetic material, arthroscopic

6.7

11.0

S22.3

ICD-10 Finland

Fracture of rib

2.3

10.9

102

461

NBF15

NOMESCO Finland

Humeroscapular synovectomy, arthroscopic

43.5

10.9

XA402

NOMESCO Finland

ENMG

3.4

10.9

157

M47.1

ICD-10 Finland

Other spondylosis with myelopathy

6.0

10.9

WX400

NOMESCO Finland

Inhalation anesthesy

2.5

10.8

357

S93.4

ICD-10 Finland

Sprain and strain of ankle

1.9

10.8

165

908

Z01.2

ICD-10 Finland

Dental examination

1.4

10.7

752

6011

SDA02

NOMESCO Finland

Parodonthologic therapy

1.4

10.7

602

4629

RD211

NOMESCO Finland

2.4

10.7

399

M01AX01

ATC

nabumetone; oral

2.5

10.7

323

D82

ICPC

Teeth/gum disease

1.4

10.7

622

4813

J45

ICD-10 Finland

Asthma

1.9

10.7

168

937

H02BX01

ATC

methylprednisolone, combinations; systemic

2.5

10.7

354

H01

ICPC

Ear pain/earache

1.8

10.7

179

1022

ZY020

NOMESCO Finland

Telephone, letter or other consultation without direct patient contact

2.1

10.6

123

610

SPAT1149

SPAT

Suture or treatment of traumatic wound

1.8

10.6

201

1190

NG1BG

NOMESCO Finland

Knee and lower leg MRI examination with high intensity magnet

2.7

10.6

269

R52.1

ICD-10 Finland

Chronic intractable pain

8.5

10.5

NF1AE

NOMESCO Finland

Hip joint ultrasound examination

3.7

10.5

125

NAG62

NOMESCO Finland

Posterior fusion of lumbar spine with fixation, 2-3 vertebraea

3.9

10.5

110

9476

FHL

Splitting of fascia or aponeurosis

14.3

10.5

A03FA02

ATC

cisapride; oral, rectal

2.0

10.5

126

634

D19

ICPC

Teeth/gum symptom/complaint

1.5

10.4

483

3577

73105

ICD-8 Finland

Bursitis chronica, inflammation of the synovial membrane, bursa and tendon sheath

+∞

10.4

ZXD10

NOMESCO Finland

Scheduled procedure

1.4

10.4

698

5532

E0000UV

ATC

1.4

10.4

708

5630

A01AB09

ATC

miconazole; local oral

1.9

10.4

154

842

J01EA01

ATC

trimethoprim; systemic

1.5

10.3

441

3211

R07.3

ICD-10 Finland

Other chest pain

1.9

10.3

152

829

NBL99

NOMESCO Finland

Other operation on muscle or tendon of shoulder or upper arm

32.7

10.3

DJD20

NOMESCO Finland

Plastic repair of septum of nose

2.7

10.3

268

M18.9

ICD-10 Finland

Arthrosis of first carpometacarpal joint, unspecified

5.1

10.3

WX720

NOMESCO Finland

Own respiration

2.6

10.3

304

KMAK

NOMESCO Finland

1.3

10.3

990

8326

8404A

ICD-9 Finland

Sprains and strains of shoulder and upper arm, Rotator cuff (capsule)

10.6

10.3

R03BB04

ATC

tiotropium bromide; inhalant

1.9

10.3

153

837

7227C

ICD-9 Finland

Intervertebral disk disorders, Intervertebral disk disorder with myelopathy[SYNDROMA ISCHIADICUM]

3.0

10.3

187

9481

FHL

Detachment or severance of a muscle or tendon

23.5

10.2

J32.0

ICD-10 Finland

Chronic maxillary sinusitis

2.0

10.2

133

694

D07AD01

ATC

clobetasol; topical

1.6

10.1

292

1945

E66.8

ICD-10 Finland

Other obesity

2.2

10.1

458

G55.2*M47.9

ICD-10 Finland

Nerve root and plexus compressions in spondylosis

4.7

10.1

M15

ICD-10 Finland

Polyarthrosis

2.4

10.1

357

M02AA15

ATC

diclofenac; topical (antiinflammatory prep., non-steroids for topical use)

1.9

10.1

140

748

D07AC01

ATC

betamethasone; topical

1.4

10.0

614

4784

N06AA10

ATC

nortriptyline; systemic

3.6

10.0

120

M51.9

ICD-10 Finland

Intervertebral disc disorder, unspecified

5.1

10.0

M79.5

ICD-10 Finland

Residual foreign body in soft tissue

5.1

10.0

NH3AA

NOMESCO Finland

Foot and toes X-ray examination

1.9

10.0

137

726

CJE20

NOMESCO Finland

Phakoemulsification with implantation of artificial lens in posterior chamber

1.5

10.0

374

2646

WYA10

NOMESCO Finland

First aid or other corresponding healthcare contact

1.9

10.0

135

714

NF1AA

NOMESCO Finland

Hip X-ray examination

2.0

10.0

121

615

L18

ICPC

Muscle pain

2.7

9.9

238

SPAT1292

SPAT

Other function in accordance with SHToL (Finnish classification of nursing interventions)

1.9

9.9

141

761

M54.8

ICD-10 Finland

Other dorsalgia

2.5

9.9

306

F32.9

ICD-10 Finland

Depressive episode, unspecified

1.7

9.9

191

1137

N03AE01

ATC

clonazepam; systemic

2.2

9.9

104

496

N06AB10

ATC

escitalopram; oral

1.5

9.9

362

2548

N01

ICPC

Headache

1.9

9.9

136

722

J01CE02

ATC

phenoxymethylpenicillin; oral

1.3

9.9

1313

11575

NBE15

NOMESCO Finland

Incision or suture of capsule of joint of shoulder, arthroscopic

20.1

9.8

NJ2MA

NOMESCO Finland

Measurement of mechanical axis of lower leg with X-ray

2.1

9.8

110

539

H57.1

ICD-10 Finland

Ocular pain

2.8

9.8

211

SHA02

NOMESCO Finland

Correction of physiology of bite - basic therapy visit

2.0

9.8

117

591

SCA01

NOMESCO Finland

Simple analysis and advice of nutrition with regard to dentistry

1.4

9.7

469

3494

J01MA12

ATC

levofloxacin; systemic

1.6

9.7

296

1995

S89.9

ICD-10 Finland

Unspecified injury of lower leg

2.8

9.7

212

L16

ICPC

Ankle symptom/complaint

1.8

9.6

152

850

G56.9

ICD-10 Finland

Mononeuropathy of upper limb, unspecified

11.4

9.6

L11

ICPC

Wrist symptom/complaint

2.0

9.5

126

662

SGA01

NOMESCO Finland

Tooth opening as first aid

1.6

9.5

285

1915

UKC02

NOMESCO Finland

Cystoscopy

1.6

9.5

228

1447

JN1AE

NOMESCO Finland

Ultrasound examination of upper part of abdomen

1.8

9.5

156

882

L02

ICPC

Back symptom/complaint

1.9

9.5

141

770

DM1QA

NOMESCO Finland

Paranasal sinuses X-ray examination in one projection

2.4

9.5

324

50099

ICD-8 Finland

Hypertrophy of tonsils and adenoids

1.7

9.5

215

1345

M65.8

ICD-10 Finland

Other synovitis and tenosynovitis

4.5

9.4

JN3BD

NOMESCO Finland

Extensive abdominal CT

1.7

9.4

182

1085

XKD00

NOMESCO Finland

Uroflowmetry

1.7

9.4

200

1226

M20.2

ICD-10 Finland

Hallux rigidus

2.7

9.4

228

R03AK06

ATC

salmeterol and fluticasone; inhalant

1.6

9.4

229

1461

M67.0

ICD-10 Finland

Short Achilles tendon (acquired)

100.4

9.4

NBF20

NOMESCO Finland

Operation for humeroscapular osteochondritis, open

100.4

9.4

K07.60

ICD-10 Finland

Snapping jaw

2.3

9.4

386

E66.00

ICD-10 Finland

Metabolic syndrome

2.2

9.4

453

SFA00

NOMESCO Finland

Small filling

1.6

9.4

236

1515

R21

ICPC

Throat symptom/complaint

1.5

9.4

298

2030

R05DA20

ATC

opium alkaloids and derivatives - combinations

1.4

9.4

454

3381

D07AB02

ATC

hydrocortisone butyrate; topical

1.4

9.3

500

3796

T89

ICPC

Diabetes insulin dependent

2.7

9.3

240

SAD01

NOMESCO Finland

Assessment of need for oral health care, standard

1.7

9.3

213

1336

S13.4

ICD-10 Finland

Sprain and strain of cervical spine

2.7

9.2

242

N05AH04

ATC

quetiapine; oral

1.6

9.2

259

1713

ZA1.0

ICD-10 Finland

Shoulder region

3.3

9.2

134

78559

ICD-8 Finland

Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD

2.5

9.2

293

J01CA08

ATC

pivmecillinam; oral

1.3

9.2

752

6128

P06

ICPC

Sleep disturbance

1.8

9.2

166

969

L28

ICPC

Limited function/disability (L)

1.7

9.2

206

1284

1410

FHL

Laparoscopy

2.5

9.2

297

N06AB03

ATC

fluoxetine; oral

1.6

9.2

225

1439

UDQ12

NOMESCO Finland

Flexible laryngoscopy

2.2

9.1

445

XJH00

NOMESCO Finland

Transanal ultrasonography

2.3

9.1

370

M15.8

ICD-10 Finland

Other polyarthrosis

4.6

9.1

NB1AD

NOMESCO Finland

Shoulder CT examination

4.6

9.1

H53.1

ICD-10 Finland

Subjective visual disturbances

2.0

9.0

109

552

C07AA05

ATC

propranolol; systemic

1.5

9.0

345

2449

AA1CG

NOMESCO Finland

Extensive MRI examination of brain with high intensity magnet

1.9

9.0

135

742

R09

ICPC

Sinus symptom/complaint

1.9

8.9

137

760

TNX00

NOMESCO Finland

Puncture and needle biopsy of soft tissue, unspecified region

4.0

8.9

J01DA08

ATC

[U] cefaclor; oral

1.8

8.9

167

986

JN3AE

NOMESCO Finland

Abdominal ultrasound examination

1.7

8.9

206

1296

G57.6

ICD-10 Finland

Lesion of plantar nerve

3.5

8.9

117

PA6BD

NOMESCO Finland

Extensive CT of neck arteries

2.5

8.8

281

R01AD08

ATC

fluticasone; nasal

1.4

8.8

523

4038

M22.4

ICD-10 Finland

Chondromalacia patellae

2.7

8.8

214

N05BA04

ATC

oxazepam; oral

1.4

8.8

422

3134

M54

ICD-10 Finland

Dorsalgia

1.7

8.8

179

1086

N02AJ13

ATC

tramadol and paracetamol; systemic

3.6

8.7

103

J46

ICD-10 Finland

Status asthmaticus

3.0

8.7

172

202

Kela drug reimbursment

Connective tissue diseases, rheumatoid arthritis and comparable disease

1.7

8.7

182

1112

C10AA03

ATC

pravastatin; oral

2.0

8.7

105

533

N92.0

ICD-10 Finland

Excessive and frequent menstruation with regular cycle

1.7

8.7

185

1135

WX308

NOMESCO Finland

Sacral anesthesy

14.1

8.7

A10AC01

ATC

insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)

2.0

8.7

107

548

NFM20

NOMESCO Finland

Excision of bursa of hip or thigh

50.2

8.7

F32.11

ICD-10 Finland

Moderate depressive episode with somatic syndrome

2.9

8.7

173

SPAT1044

SPAT

Tympanometry

3.3

8.6

125

N39.3

ICD-10 Finland

Stress incontinence

1.8

8.6

143

813

SPAT1240

SPAT

Therapeutic discussion

1.7

8.6

164

973

NGF35

NOMESCO Finland

Plastic operation of joint cartilage of knee

2.5

8.6

254

N06AX26

ATC

vortioxetine; oral

2.1

8.6

453

A10AB01

ATC

insulin (human); parenteral (insulins and analog. for injection, fast-acting)

2.7

8.6

221

D01AC20

ATC

imidazoles/triazoles in combination with corticosteroids; topical

1.4

8.6

405

2996

FN1BC

NOMESCO Finland

Extensive angiography of hear and/or coronary arteries

2.3

8.5

322

TAB00

NOMESCO Finland

Lumbar puncture

2.2

8.5

385

SPAT1360

SPAT

Extensive global examination

1.9

8.5

116

618

EBA00

NOMESCO Finland

Extraction of tooth

1.4

8.5

532

4141

ABC16

NOMESCO Finland

Microsurgical excision of lumbar intervertebral disc displacement

2.4

8.5

275

I10

ICD-10 Finland

Essential (primary) hypertension

1.3

8.5

958

8163

AA1BG

NOMESCO Finland

Standard MRI examination of brain with high intensity magnet

1.8

8.5

140

796

I70.2

ICD-10 Finland

Atherosclerosis of arteries of extremities

2.1

8.4

488

7151A

ICD-9 Finland

Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, primary[OSTEOARTHROSIS PRIMARIA, OLKANIVEL]

90.4

8.4

R60.0

ICD-10 Finland

Localized oedema

1.8

8.4

154

905

M43.1

ICD-10 Finland

Spondylolisthesis

2.4

8.4

299

L09

ICPC

Arm symptom/complaint

2.3

8.4

320

M76.0

ICD-10 Finland

Gluteal tendinitis

4.1

8.4

V700A

ICD-9 Finland

General medical examination, Routine general medical examination at a health care facility

2.9

8.3

173

SPAT1101

SPAT

Orthostatic test

2.4

8.3

290

R02

ICPC

Shortness of breath/dyspnoea

1.7

8.3

167

1009

NB1BG

SPAT

5.0

8.3

7245A

ICD-9 Finland

Other and unspecified disorders of back, Backache, unspecified

6.2

8.3

M79.9

ICD-10 Finland

Soft tissue disorder, unspecified

8.6

8.3

SDA01

NOMESCO Finland

Simple parodonthologic therapy

1.4

8.3

437

3302

N83.2

ICD-10 Finland

Other and unspecified ovarian cysts

1.6

8.3

203

1297

M01AE11

ATC

tiaprofenic acid; oral, rectal

2.4

8.2

285

RF420

NOMESCO Finland

3.9

8.2

C08CA01

ATC

amlodipine; oral

1.4

8.2

552

4345

J01FA15

ATC

telithromycin; oral

1.6

8.2

195

1236

M47.81

ICD-10 Finland

Other spondylosis, occipito-atlanto-axial region

6.5

8.2

Z00.4

ICD-10 Finland

General psychiatric examination, not elsewhere classified

1.8

8.2

132

744

W01

ICD-10 Finland

Fall on same level from slipping, tripping and stumbling

1.4

8.2

438

3317

ZXA10

NOMESCO Finland

Bilateral

1.5

8.1

292

2041

H81.1

ICD-10 Finland

Benign paroxysmal vertigo

1.7

8.1

158

948

M70.0

ICD-10 Finland

Chronic crepitant synovitis of hand and wrist

11.7

8.1

S01

ICPC

Pain/tenderness of skin

2.4

8.1

282

M51.8

ICD-10 Finland

Other specified intervertebral disc disorders

4.8

8.1

C03CA01

ATC

furosemide; systemic

1.4

8.1

349

2536

25000

ICD-8 Finland

Diabetes mellitus, Sine complicatione

3.0

8.0

158

N02CC06

ATC

eletriptan; oral

2.3

8.0

314

NHL14

NOMESCO Finland

Shortening or lengthening of achilles tendon

8.9

8.0

G01AA10

ATC

clindamycin; vaginal

1.5

8.0

318

2270

NBK92

NOMESCO Finland

Other operation on bone of shoulder or upper arm, clavicle

22.1

8.0

TAB20

NOMESCO Finland

Epidural puncture

5.3

8.0

S63.5

ICD-10 Finland

Sprain and strain of wrist

2.7

8.0

203

FN1CD

NOMESCO Finland

Very extensive CT of coronary arteries

4.8

7.9

A10AB04

ATC

insulin lispro; parenteral (insulins and analog. for injection, fast-acting)

2.6

7.9

207

C05AA08

ATC

fluocortolone; rectal, topical

1.5

7.9

254

1734

R01AD01

ATC

beclometasone; nasal

1.5

7.9

293

2063

WX700

NOMESCO Finland

Respiratory and circulatory monitoring

1.5

7.8

245

1662

SPAT1193

SPAT

Pap smear

1.7

7.8

175

1088

M01AB01

ATC

indometacin; systemic, rectal

1.9

7.8

110

590

N30.0

ICD-10 Finland

Acute cystitis

1.6

7.8

208

1358

I49.1

ICD-10 Finland

Atrial premature depolarization

2.5

7.8

236

H02.3

ICD-10 Finland

Blepharochalasis

1.9

7.8

104

549

W00

ICD-10 Finland

Fall on same level involving ice and snow

1.7

7.8

175

1093

R51

ICD-10 Finland

Headache

2.1

7.8

393

TAC00

NOMESCO Finland

Peripheral nerve block

10.8

7.8

I20.09

ICD-10 Finland

Unstable angina

2.2

7.8

326

SPAT1106

SPAT

Acupuncture

7.0

7.8

G03DB01

ATC

dydrogesterone; oral

1.5

7.8

275

1916

S01CA01

ATC

dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)

1.3

7.7

553

4391

Z03.3

ICD-10 Finland

Observation for suspected nervous system disorder

2.0

7.7

472

S80.0

ICD-10 Finland

Contusion of knee

2.0

7.7

101

528

Z04.8

ICD-10 Finland

Examination and observation for other specified reasons

1.6

7.7

185

1175

K57.3

ICD-10 Finland

Diverticular disease of large intestine without perforation or abscess

1.5

7.7

256

1759

B01AB05

ATC

enoxaparin; parenteral

1.4

7.7

490

3815

DMB20

NOMESCO Finland

Functional endoscopic opening of maxillary antrum

2.0

7.7

488

JAH01

NOMESCO Finland

Laparoscopy

2.1

7.7

398

WX199

NOMESCO Finland

Other local analgesia

2.9

7.7

152

G50.1

ICD-10 Finland

Atypical facial pain

3.5

7.7

G04CA02

ATC

tamsulosin; oral

1.5

7.7

260

1797

L10

ICPC

Elbow symptom/complaint

2.2

7.6

343

NDG60

NOMESCO Finland

Arthroplasty of first CMC joint

3.8

7.6

NH1BG

NOMESCO Finland

Ankle and foot MRI examination with high intensity magnet

4.4

7.6

R06AX27

ATC

desloratadine; oral

1.4

7.6

489

3812

7233A

ICD-9 Finland

Other disorders of cervical region, Cervicobrachial syndrome (diffuse)

18.4

7.6

R75

ICPC

Sinusitis acute/chronic

2.2

7.6

369

M01AB16

ATC

aceclofenac; oral

2.4

7.6

272

I49.9

ICD-10 Finland

Cardiac arrhythmia, unspecified

1.6

7.6

182

1155

AB5CT

NOMESCO Finland

Blockage of nerv root with CT guidance

11.9

7.6

S49.9

ICD-10 Finland

Unspecified injury of shoulder and upper arm

3.9

7.5

M24.4

ICD-10 Finland

Recurrent dislocation and subluxation of joint

5.2

7.5

N06AB04

ATC

citalopram; systemic

1.4

7.5

376

2805

M76.9

ICD-10 Finland

Enthesopathy of lower limb, unspecified

6.2

7.5

JHB30

NOMESCO Finland

Rubber band ligature of haemorrhoids or prolapse of mucosa

1.9

7.5

104

558

A10AE04

ATC

insulin glargine; parenteral

1.8

7.5

137

804

W22

ICD-10 Finland

Striking against or struck by other object(s)

2.1

7.5

422

NB1AA

SPAT

2.9

7.5

156

AN4

Balloon angioplasty and drug eluding stent

2.7

7.5

186

L04AX03

ATC

methotrexate; systemic (immunosuppressants)

1.7

7.5

154

939

M16.1

ICD-10 Finland

Other primary coxarthrosis

1.7

7.4

160

987

Y83

ICD-10 Finland

Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

1.8

7.4

115

642

N02CC04

ATC

rizatriptan; oral

1.8

7.4

113

628

AB5BT

NOMESCO Finland

Blockage of nerv root with X-ray guidance

6.5

7.4

G45.0

ICD-10 Finland

Vertebro-basilar artery syndrome

2.9

7.4

141

R50.9

ICD-10 Finland

Fever, unspecified

1.6

7.4

214

1427

H60.9

ICD-10 Finland

Otitis externa, unspecified

1.9

7.4

107

585

H90.3

ICD-10 Finland

Sensorineural hearing loss, bilateral

1.5

7.4

231

1570

N39.0

ICD-10 Finland

Urinary tract infection, site not specified

1.6

7.3

189

1224

R03AC12

ATC

salmeterol; inhalant

2.2

7.3

316

N39.4

ICD-10 Finland

Other specified urinary incontinence

1.8

7.3

123

705

71798

ICD-8 Finland

Other nonarticular rheumatism, Other muscular rheumatism, fibrositis and myalgia

+∞

7.3

7270X

ICD-9 Finland

Other disorders of synovium, tendon and bursa, Synovitis and tenosynovitis[TENOSYNOVITIS ALIA LOCO DEFINITO]

+∞

7.3

I20.99

ICD-10 Finland

Angina pectoris, unspecified

2.1

7.3

400

NE1BG

NOMESCO Finland

Pelvic, hip and femur MRI examination with high intensity magnet

2.9

7.3

147

WX419

NOMESCO Finland

Other general anesthesy

4.5

7.3

SPAT1111

SPAT

Planning of analgesia

4.5

7.3

F20.00

ICD-10 Finland

Paranoid schizophrenia continuous

0.0

7.2

213

205

Kela drug reimbursment

Chronic hypertension

1.4

7.2

398

3026

D11

ICPC

Diarrhoea

1.7

7.2

159

988

M54.0

ICD-10 Finland

Panniculitis affecting regions of neck and back

3.7

7.2

G43.9

ICD-10 Finland

Migraine, unspecified

1.9

7.2

488

ABC30

NOMESCO Finland

Decompression of cervical nerve roots

4.8

7.1

E10.00

ICD-10 Finland

Insulin-dependent diabetes diabetic hypoglycemic coma

5.0

7.1

J45.1

ICD-10 Finland

Nonallergic asthma

1.9

7.1

101

549

TDW99

NOMESCO Finland

Other minor procedure in surgery of ear, nose and larynx

2.4

7.1

243

TNB11

NOMESCO Finland

Injection of diagnostic or therapeutic substance in shoulder joint

6.0

7.1

3540A

ICD-9 Finland

Mononeuritis of upper limb and mononeuritis multiplex, Carpal tunnel syndrome

5.6

7.1

NA2BG

NOMESCO Finland

Thoracal spine MRI examination with high intensity magnet

3.4

7.0

G45.9

ICD-10 Finland

Transient cerebral ischaemic attack, unspecified

1.8

7.0

108

603

JKA21

NOMESCO Finland

Laparoscopic cholecystectomy

1.6

7.0

193

1269

K10.3

ICD-10 Finland

Alveolitis of jaws

2.1

7.0

344

I20.89

ICD-10 Finland

Other angina pectoris unspecified coronary artery status

2.6

7.0

193

R06AE09

ATC

levocetirizine; oral

1.5

7.0

252

1763

RF410

NOMESCO Finland

3.6

7.0

K35.9

ICD-10 Finland

Acute appendicitis, unspecified

1.8

7.0

113

642

NC1AA

NOMESCO Finland

Elbow X-ray examination without contrast

2.7

6.9

170

S01GX01

ATC

cromoglicic acid; ophthalmic

1.4

6.9

337

2503

206

Kela drug reimbursment

Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease

1.5

6.9

207

1388

G55.1

ICD-10 Finland

Nerve root and plexus compressions in intervertebral disc disorders

5.5

6.9

M70.4

ICD-10 Finland

Prepatellar bursitis

4.2

6.9

M18.0

ICD-10 Finland

Primary arthrosis of first carpometacarpal joints, bilateral

3.5

6.9

S83.2

ICD-10 Finland

Tear of meniscus, current

1.8

6.9

117

673

R23.8

ICD-10 Finland

Other and unspecified skin changes

1.5

6.8

242

1689

R5599

NOMESCO Finland

Other rehabilitation service

2.8

6.8

149

SGC00

NOMESCO Finland

Local medication of root channels of tooth

1.6

6.8

182

1189

B02AA02

ATC

tranexamic acid; systemic

1.4

6.8

305

2228

C09CA06

ATC

candesartan; oral

1.4

6.8

367

2774

ND1AA

NOMESCO Finland

Wrist X-ray examination

1.9

6.8

519

9103

FHL

Partial or complete bone removal

9.3

6.8

NH3BA

NOMESCO Finland

Foot and toes extensive X-ray examination

2.3

6.8

247

NBM20

NOMESCO Finland

Excision of bursa of shoulder or upper arm

40.2

6.8

N06AX03

ATC

mianserin; oral

2.0

6.8

397

A10BH01

ATC

sitagliptin; oral

1.7

6.7

142

872

NB1ZT

SPAT

16.7

6.7

K04.0

ICD-10 Finland

Pulpitis

1.6

6.7

153

957

R30.0

ICD-10 Finland

Dysuria

2.4

6.7

230

M43.0

ICD-10 Finland

Spondylolysis

3.2

6.7

100

SPAT1053

SPAT

Memory test

1.6

6.7

176

1145

NGB20

NOMESCO Finland

Primary total prosthetic replacement of knee joint without patellar part

1.7

6.7

143

883

XCW99

NOMESCO Finland

Other investigative procedure of eye

1.6

6.7

159

1010

SPAT1059

SPAT

Spirometry at the office

2.0

6.7

415

I25.9

ICD-10 Finland

Chronic ischaemic heart disease, unspecified

1.8

6.7

101

561

SPAT1285

SPAT

Provision of consultation response

2.0

6.7

430

N07BA03

ATC

varenicline; oral

1.9

6.6

517

NH3EA

NOMESCO Finland

Feet X-ray examination with load

3.0

6.6

123

A12AX

ATC

Calcium, combinations with vitamin D and/or other drugs

1.3

6.6

526

4227

SBB00

NOMESCO Finland

Fotograf of mouth and teeth

2.3

6.6

252

L14

ICPC

Leg/thigh symptom/complaint

1.8

6.6

548

TEW99

NOMESCO Finland

Other minor procedure in surgery of teeth, jaws, mouth and pharynx

2.0

6.6

393

F33.2

ICD-10 Finland

Recurrent depressive disorder, current episode severe without psychotic symptoms

2.0

6.6

393

F45.8

ICD-10 Finland

Other somatoform disorders

1.8

6.6

106

599

1300

FHL

Esophagogastroduodenoscopy (also includes staining)

5.5

6.6

9211

FHL

Exploration or removal of diskusprolapse

2.9

6.6

133

D17.2

ICD-10 Finland

Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs

2.9

6.6

133

OAA65

SPAT

1.6

6.6

169

1094

CK2X4

NOMESCO Finland

Optical coherence tomography (OCT) of ocular fundus

1.7

6.6

132

800

R00.0

ICD-10 Finland

Tachycardia, unspecified

2.2

6.6

299

G04BD12

ATC

mirabegron; oral

1.7

6.6

142

880

H92.0

ICD-10 Finland

Otalgia

2.0

6.5

425

K74

ICPC

Ischaemic heart dis with angina

4.3

6.5

JDF11

NOMESCO Finland

Laparoscopic gastric bypass

3.0

6.5

119

ND2BA

NOMESCO Finland

Hand and fingers extensive X-ray examination

2.8

6.5

135

L30.9

ICD-10 Finland

Dermatitis, unspecified

1.4

6.5

269

1937

K01

ICPC

Heart pain

4.0

6.5

SAB01

NOMESCO Finland

Restricted oral and dental health check by dental hygienist or dental assistant

1.7

6.5

136

836

4730A

ICD-9 Finland

Chronic sinusitis, Maxillary

3.3

6.5

A03

ICPC

Fever

1.5

6.5

233

1630

R00.2

ICD-10 Finland

Palpitations

1.7

6.5

117

686

A03DA02

ATC

pitofenone and analgesics; systemic

2.9

6.4

120

Z02.7

ICD-10 Finland

Issue of medical certificate

1.9

6.4

447

L83

ICPC

Neck syndrome

5.7

6.4

A07AA02

ATC

nystatin; oral

1.9

6.4

506

C10AA04

ATC

fluvastatin; oral

1.7

6.4

115

673

M70.8

ICD-10 Finland

Other soft tissue disorders related to use, overuse and pressure

7.4

6.4

FB1BD

NOMESCO Finland

Extensive CT examination of arteria pulmonalis

1.8

6.4

110

638

SPAT1305

SPAT

Counselling and guidance related to physical exercise

1.7

6.4

140

867

K80.2

ICD-10 Finland

Calculus of gallbladder without cholecystitis

1.5

6.4

192

1293

C08DA01

ATC

verapamil; systemic

2.1

6.4

298

7151F

ICD-9 Finland

Osteo-arthrosis and allied disorders, Osteo-arthrosis, localised, primary[OSTEOARTHROSIS PRIMARIA, POLVI]

3.0

6.3

110

Z03.9

ICD-10 Finland

Observation for suspected disease or condition, unspecified

1.4

6.3

259

1857

N17

ICPC

Vertigo/dizziness

1.6

6.3

146

920

R03BB01

ATC

ipratropium bromide; inhalant

2.4

6.3

216

M09AX01

ATC

hyaluronic acid; parenteral

2.1

6.3

325

J01MA14

ATC

moxifloxacin; systemic

1.6

6.3

138

859

I84.9

ICD-10 Finland

Unspecified hemorrhoids without complication

1.9

6.3

474

285

Kela drug reimbursment

Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)

1.9

6.3

431

A02BX02

ATC

sucralfate; oral

2.2

6.3

279

ABC10

NOMESCO Finland

Microsurgical excision of cervical intervertebral disc displacement

11.0

6.3

J01FA01

ATC

erythromycin; systemic

1.5

6.3

224

1564

SPAT1229

SPAT

Assessment of need for aid

1.8

6.3

103

586

A10AE05

ATC

insulin detemir; parenteral

2.0

6.3

404

PA7CD

NOMESCO Finland

CT angiography of neck and brain, extensive

3.7

6.3

SBB10

NOMESCO Finland

Teeth copy

1.9

6.3

477

NBH98

NOMESCO Finland

Other operation on joint of shoulder, arthroscopic

+∞

6.3

7270A

ICD-9 Finland

Other disorders of synovium, tendon and bursa, Synovitis and tenosynovitis[TENOSYNOVITIS STYLOIDEI RADII (QUERVAIN)]

+∞

6.3

7288X

ICD-9 Finland

Disorders of muscle, ligament and fascia, Other disorders of muscle, ligament and fascia[MORBI MUSCULI, LIGAMENTI ET FASCIAE ALIA DEFINITA]

+∞

6.3

XQ800

NOMESCO Finland

Prick test

1.7

6.2

122

732

WX404

NOMESCO Finland

Intravenous generell anesthesy

1.4

6.2

359

2742

H43.8

ICD-10 Finland

Other disorders of vitreous body

1.6

6.2

150

957

9502

FHL

Tendon splitting (De Quervain, click finger)

26.7

6.2

Z71.8

ICD-10 Finland

Other specified counselling

1.4

6.2

366

2809

H25.1

ICD-10 Finland

Senile nuclear cataract

1.4

6.2

288

2121

R39.1

ICD-10 Finland

Other difficulties with micturition

2.6

6.2

159

Z71.3

ICD-10 Finland

Dietary counselling and surveillance

2.0

6.2

400

M71.9

ICD-10 Finland

Bursopathy, unspecified

5.7

6.1

K04.08

ICD-10 Finland

Other specified pulpit

1.8

6.1

104

601

SPAT1222

SPAT

Counselling/guidance promoting independent living

1.5

6.1

195

1327

R35

ICD-10 Finland

Polyuria

1.9

6.1

474

9212

FHL

Other posterior root decompression surgery (eg laminectomy, Gill)

7.7

6.1

M01AB51

ATC

indometacin, combinations; oral, rectal

2.6

6.1

160

J31.0

ICD-10 Finland

Chronic rhinitis

1.7

6.1

121

733

S63.6

ICD-10 Finland

Sprain and strain of finger(s)

2.3

6.1

217

SXA20

NOMESCO Finland

Local application of medicine to mouth

1.9

6.0

467

M19.2

ICD-10 Finland

Other secondary arthrosis

4.4

6.0

FM1BD

NOMESCO Finland

Extensive CT of heart

6.7

6.0

WX204

NOMESCO Finland

Axillary plexus blockaced

2.5

6.0

180

F43.1

ICD-10 Finland

Post-traumatic stress disorder

2.7

6.0

138

NAME	M13_CALCIFICTEND
CONTROL_EXCLUDE	M13_SOFTTISSUE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M753
HD_ICD_9	7261A
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	M753
COD_ICD_9	7261A
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Parameter	HR [95% CI]	p-value
M13_CALCIFICTEND	0.703 [0.6, 0.82]	< 0.001
Birth year	0.994 [0.99, 1.0]	0.191

Parameter	HR [95% CI]	p-value
M13_CALCIFICTEND	0.85 [0.74, 0.98]	0.028
Birth year	0.986 [0.98, 1.0]	0.005

N-year risk	Females	Males
1	0.07%	0.15%
5	0.424%	0.992%
10	0.991%	2.365%
15	1.956%	4.545%
20	3.591%	7.657%

Calcific tendinitis of shoulder

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints