Risteys · M13_DORSOPATHYNAS

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — M53.8, M53.9 Hospital discharge: ICD-9 — 724[8-9] Cause of death: ICD-10 — M53.8, M53.9 Cause of death: ICD-9 — 724[8-9] 2 out of 7 registries used, show all original rules.	1421
4. Check minimum number of events None	1421
5. Include endpoints None	1421
6. Filter based on genotype QC (FinnGen only)	1421

	All	Female	Male
Number of individuals
Whole population	12158	7344	4708
Only index persons	9530	5830	3700
Unadjusted period prevalence (%)
Whole population	0.18	0.21	0.13
Only index persons	0.19	0.21	0.14
Median age at first event (years)
Whole population	52.23	53.59	49.84
Only index persons	48.02	49.53	45.65

	All	Female	Male
Number of individuals	1421	933	488
Unadjusted period prevalence (%)	0.28	0.32	0.22
Median age at first event (years)	48.11	47.06	50.10

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
1290: Matched controls
12898

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

M51.1

ICD-10 Finland

Lumbar and other intervertebral disc disorders with radiculopathy

96.3

323.0

372

7249X

ICD-9 Finland

Other and unspecified disorders of back, Other unspecified back disorders

+∞

323.0

331

M53.9

ICD-10 Finland

Dorsopathy, unspecified

831.5

323.0

511

M53.8

ICD-10 Finland

Other specified dorsopathies

430.5

323.0

391

M51.3

ICD-10 Finland

Other specified intervertebral disc degeneration

81.3

224.2

250

M48.0

ICD-10 Finland

Spinal stenosis

68.1

213.0

244

NA3BG

NOMESCO Finland

Lumbar spine MRI examination with high intensity magnet

46.2

211.4

260

M54.5

ICD-10 Finland

Low back pain

6.3

177.3

601

1564

N03AX16

ATC

pregabalin; oral

6.8

162.5

486

1048

N02AX02

ATC

tramadol; systemic, rectal

5.0

156.1

750

2802

N03AX12

ATC

gabapentin; oral

9.4

152.0

346

486

M54.4

ICD-10 Finland

Lumbago with sciatica

9.6

142.6

317

423

M47.2

ICD-10 Finland

Other spondylosis with radiculopathy

100.4

131.2

143

M54.9

ICD-10 Finland

Dorsalgia, unspecified

10.3

117.4

247

291

ABC36

NOMESCO Finland

Decompression of lumbar nerve roots

178.4

95.6

NA3AA

NOMESCO Finland

Lumbar spine X-ray examination without contrast

11.1

88.4

175

179

NA3CG

NOMESCO Finland

Lumbar spine extensive MRI examination with high intensity magnet

40.5

85.7

108

M54.3

ICD-10 Finland

Sciatica

18.7

80.4

126

7227C

ICD-9 Finland

Intervertebral disk disorders, Intervertebral disk disorder with myelopathy[SYNDROMA ISCHIADICUM]

+∞

80.0

N02AE01

ATC

buprenorphine; parenteral, sublingual, transdermal

6.1

78.8

234

450

M03BX02

ATC

tizanidine; oral

3.1

78.3

886

5336

NA3EA

NOMESCO Finland

Lumbar spine X-ray examination with flexion

272.7

76.3

7248X

ICD-9 Finland

Other and unspecified disorders of back, Other symptoms referable to back

+∞

75.8

R10.4

ICD-10 Finland

Other and unspecified abdominal pain

3.1

73.9

561

2545

L03

ICPC

Low back symptom/complaint

3.8

72.3

366

1214

N06AX21

ATC

duloxetine; oral

5.9

71.5

218

430

M03BC01

ATC

orphenadrine (citrate); systemic

3.6

71.2

393

1396

NA1BG

NOMESCO Finland

Cervical spine MRI examination with high intensity magnet

17.8

71.0

113

M79.6

ICD-10 Finland

Pain in limb

3.1

70.5

549

2513

M54.2

ICD-10 Finland

Cervicalgia

9.9

67.3

141

158

M50.1

ICD-10 Finland

Cervical disc disorder with radiculopathy

41.6

65.6

N06AA09

ATC

amitriptyline; systemic

5.5

65.5

210

438

ABC16

NOMESCO Finland

Microsurgical excision of lumbar intervertebral disc displacement

648.5

63.4

M43.1

ICD-10 Finland

Spondylolisthesis

49.9

58.9

M47.9

ICD-10 Finland

Spondylosis, unspecified

55.1

57.4

N02AA59

ATC

codeine, combinations excl. psycholeptics; systemic

2.6

57.2

640

3525

A02BC02

ATC

pantoprazole; systemic

2.6

56.7

887

5880

SPAT1223

SPAT

Implementation of physical therapy rehabilitation plan

2.9

55.4

431

1902

G44.2

ICD-10 Finland

Tension-type headache

3.9

51.9

238

704

M54.6

ICD-10 Finland

Pain in thoracic spine

7.2

51.7

132

202

A02BC03

ATC

lansoprazole; oral

2.7

50.6

440

2056

M54.1

ICD-10 Finland

Radiculopathy

17.1

49.3

M01AB05

ATC

diclofenac; systemic, rectal

2.5

49.1

894

6169

M01AE03

ATC

ketoprofen; systemic, rectal

2.5

48.6

549

2958

N02AJ06

ATC

codeine and paracetamol; systemic

2.5

47.9

504

2605

M01AH05

ATC

etoricoxib; oral

2.4

47.5

788

5143

M53.1

ICD-10 Finland

Cervicobrachial syndrome

4.6

47.1

178

436

M47.82

ICD-10 Finland

Other spondylosis, cervical region

24.8

46.7

L86

ICPC

Back syndrome with radiating pain

8.9

46.5

102

123

NAG40

NOMESCO Finland

Anterior fusion of cervical spine without fixation

+∞

46.1

R52.2

ICD-10 Finland

Other chronic pain

11.3

45.8

R07.4

ICD-10 Finland

Chest pain, unspecified

2.7

45.8

382

1720

R29.8

ICD-10 Finland

Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems

4.7

45.5

166

392

N02BE01

ATC

paracetamol; systemic, rectal

2.9

45.5

1115

8842

N02AA05

ATC

oxycodone; systemic

3.5

45.4

235

763

R51.80

ICD-10 Finland

Headache

3.5

45.3

236

769

M01AH02

ATC

rofecoxib; oral

3.5

42.8

222

719

NA2BG

NOMESCO Finland

Thoracal spine MRI examination with high intensity magnet

32.4

42.6

M01AH01

ATC

celecoxib; oral (coxibs)

3.0

42.6

282

1091

M50.3

ICD-10 Finland

Other cervical disc degeneration

47.2

41.2

M54.8

ICD-10 Finland

Other dorsalgia

9.8

41.2

M01AB55

ATC

diclofenac, combinations; oral

5.2

41.1

136

288

F45.4

ICD-10 Finland

Persistent somatoform pain disorder

25.8

40.9

H02AB06

ATC

prednisolone; systemic

2.2

40.9

633

3880

UJD10

NOMESCO Finland

Esophagoscopy, gastroscopy and duodenoscopy

2.5

40.7

403

1980

M03BC51

ATC

orphenadrine, combinations; systemic

2.5

40.4

405

2002

M51.9

ICD-10 Finland

Intervertebral disc disorder, unspecified

409.6

40.3

M79.0

ICD-10 Finland

Rheumatism, unspecified

8.2

39.7

118

A02BC05

ATC

esomeprazole; systemic

2.3

39.6

546

3158

NAG62

NOMESCO Finland

Posterior fusion of lumbar spine with fixation, 2-3 vertebraea

206.1

39.0

M47.80

ICD-10 Finland

Other spondylosis, multiple sites in spine

25.5

38.7

M25.5

ICD-10 Finland

Pain in joint

2.5

38.6

395

1964

R42

ICD-10 Finland

Dizziness and giddiness

2.7

38.5

320

1416

9211

FHL

Exploration or removal of diskusprolapse

388.3

38.2

7245A

ICD-9 Finland

Other and unspecified disorders of back, Backache, unspecified

+∞

37.7

N06CA01

ATC

amitriptyline and psycholeptics; systemic

3.8

37.7

173

504

N02AC04

ATC

dextropropoxyphene; oral

7.6

36.6

123

M79.1

ICD-10 Finland

Myalgia

3.3

35.9

203

695

M75.1

ICD-10 Finland

Rotator cuff syndrome

2.6

35.7

319

1461

A02BA02

ATC

ranitidine; systemic

2.6

35.6

297

1310

Z01.8

ICD-10 Finland

Other specified special examinations

2.6

35.1

304

1370

N06AX16

ATC

venlafaxine; oral

3.1

34.2

214

786

M53.0

ICD-10 Finland

Cervicocranial syndrome

4.2

33.2

133

342

R10.3

ICD-10 Finland

Pain localized to other parts of lower abdomen

2.5

32.7

299

1379

A02BC01

ATC

omeprazole; systemic

2.3

32.5

384

2017

UJF32

NOMESCO Finland

Coloscopy

2.4

32.2

342

1707

NA6BG

NOMESCO Finland

Sacro-iliac joint MRI examination with high intensity magnet

73.8

32.0

M53.3

ICD-10 Finland

Sacrococcygeal disorders, not elsewhere classified

35.2

32.0

M70.6

ICD-10 Finland

Trochanteric bursitis

3.3

31.9

176

589

R10.1

ICD-10 Finland

Pain localized to upper abdomen

2.8

31.8

236

963

M51.8

ICD-10 Finland

Other specified intervertebral disc disorders

169.1

31.8

NA3AD

NOMESCO Finland

Lumbar spine and sacrum CT examination

18.1

31.6

M01AX17

ATC

nimesulide; oral

2.4

31.6

336

1675

ABC26

NOMESCO Finland

Open discectomy of lumbar spine

+∞

31.4

7231A

ICD-9 Finland

Other disorders of cervical region, Cervicalgia

+∞

31.4

G55.1*M51.1

ICD-10 Finland

Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions

40.2

31.3

N05CF01

ATC

zopiclone; oral

2.2

31.2

435

2459

N06AX11

ATC

mirtazapine; oral

2.2

31.0

420

2341

M53.2

ICD-10 Finland

Spinal instabilities

320.2

31.0

NA7EA

NOMESCO Finland

Scoliosis X-ray examination

+∞

30.3

M03BA52

ATC

carisoprodol, combinations excl. psycholeptics; oral

6.4

30.2

136

N05BA01

ATC

diazepam; systemic, rectal

2.9

29.9

207

809

M35.7

ICD-10 Finland

Hypermobility syndrome

26.4

29.8

R52.9

ICD-10 Finland

Pain, unspecified

3.6

29.7

141

420

M01AE02

ATC

naproxen; oral, rectal

1.9

29.0

714

5017

R03AC02

ATC

salbutamol; inhalant

1.9

28.9

661

4520

M54

ICD-10 Finland

Dorsalgia

3.3

28.4

158

530

7890A

ICD-9 Finland

Other symptoms involving abdomen and pelvis, Abdominal pain

4.5

28.4

106

254

72510

ICD-8 Finland

Displacement of intervertebral disk, Lumbalis cum prolapsu disci

+∞

28.2

M45

ICD-10 Finland

Ankylosing spondylitis

48.3

27.5

M41.9

ICD-10 Finland

Scoliosis, unspecified

48.3

27.5

J06.9

ICD-10 Finland

Acute upper respiratory infection, unspecified

2.0

27.5

536

3430

GD1AA

NOMESCO Finland

Thorax X-ray examination

2.0

27.3

533

3409

WX700

NOMESCO Finland

Respiratory and circulatory monitoring

2.6

27.2

220

940

72880

ICD-8 Finland

Vertebrogenic pain syndrome, Radicula syndrome of lower limbs

+∞

27.2

ABC56

NOMESCO Finland

Decompression of lumbar spinal canal and nerve roots

+∞

27.2

UKC02

NOMESCO Finland

Cystoscopy

2.7

26.8

209

874

M01AC06

ATC

meloxicam; systemic, rectal

2.0

26.5

470

2885

N03AE01

ATC

clonazepam; systemic

4.4

26.4

100

243

SPAT1230

SPAT

Aid fitting and borrowing and monitoring of use

2.5

26.4

227

1001

NA1AA

NOMESCO Finland

Cervical spine X-ray examination without contrast

8.5

25.8

WX408

NOMESCO Finland

General anesthesy, balanced

2.1

25.4

347

1911

J20.9

ICD-10 Finland

Acute bronchitis, unspecified

2.4

25.4

240

1113

J01.0

ICD-10 Finland

Acute maxillary sinusitis

2.2

25.3

294

1507

G56.0

ICD-10 Finland

Carpal tunnel syndrome

2.8

24.9

171

660

R06.0

ICD-10 Finland

Dyspnoea

2.2

24.5

306

1619

M02AA07

ATC

piroxicam; topical

1.9

24.4

470

2956

Z04.8

ICD-10 Finland

Examination and observation for other specified reasons

2.8

24.3

169

658

J01DB01

ATC

cefalexin; oral

2.0

24.1

1024

8475

M75.4

ICD-10 Finland

Impingement syndrome of shoulder

3.7

24.0

109

312

F32.9

ICD-10 Finland

Depressive episode, unspecified

2.8

24.0

167

651

NA1CG

NOMESCO Finland

Cervical spine extensive MRI examination with high intensity magnet

13.6

23.8

M79.7

ICD-10 Finland

Fibromyalgia

6.4

23.6

103

M01AX01

ATC

nabumetone; oral

4.9

23.3

167

A06AD11

ATC

lactulose; oral

2.5

23.2

193

833

ZXE10

NOMESCO Finland

More than one and less than three hours

1.9

23.1

468

2984

AA1AD

NOMESCO Finland

CT of head and brain

2.1

23.1

295

1572

L01

ICPC

Neck symptom/complaint

2.6

22.9

177

734

A01

ICPC

Pain general/multiple sites

3.6

22.8

109

326

J01DA01

ATC

[U] cefalexin; systemic

1.8

22.6

786

5984

M43.0

ICD-10 Finland

Spondylolysis

122.1

22.6

N06AB04

ATC

citalopram; systemic

2.1

22.1

290

1558

J01FA06

ATC

roxithromycin; oral

1.8

22.0

526

3531

M46.9

ICD-10 Finland

Inflammatory spondylopathy, unspecified

+∞

21.9

72870

ICD-8 Finland

Vertebrogenic pain syndrome, Lumbalgia

+∞

21.9

K21.0

ICD-10 Finland

Gastro-oesophageal reflux disease with oesophagitis

2.9

21.8

142

529

EB1HA

NOMESCO Finland

Panorama tomography of teeth and jaws or similar X-ray examination

1.8

21.7

483

3163

WX110

NOMESCO Finland

Local anesthesy

1.8

21.7

840

6576

Z00.4

ICD-10 Finland

General psychiatric examination, not elsewhere classified

3.1

21.7

124

424

SPAT1229

SPAT

Assessment of need for aid

3.3

21.7

114

367

J01MA02

ATC

ciprofloxacin; systemic

1.8

21.5

476

3110

ZXD10

NOMESCO Finland

Scheduled procedure

1.8

21.5

497

3292

A09

ICD-10 Finland

Other gastroenteritis and colitis of infectious and unspecified origin

2.4

21.4

207

964

G47.3

ICD-10 Finland

Sleep apnoea

2.1

21.2

263

1373

M01AB51

ATC

indometacin, combinations; oral, rectal

7.1

21.1

R01AD09

ATC

mometasone; nasal

1.8

21.0

557

3850

L08

ICPC

Shoulder symptom/complaint

2.2

21.0

235

1173

M54.0

ICD-10 Finland

Panniculitis affecting regions of neck and back

18.2

20.9

SPAT1301

SPAT

No procedures

1.9

20.6

387

2380

SPAT1253

SPAT

Initiation, adjustment, discontinuation or repetition of medication

1.9

20.5

373

2266

SPAT1263

SPAT

Sampling

1.8

20.4

506

3416

J01AA02

ATC

doxycycline; systemic

1.8

20.3

981

8151

A06AC01

ATC

ispaghula (psylla seeds); oral

2.0

20.2

295

1648

L28

ICPC

Limited function/disability (L)

2.3

19.7

191

889

P01AB01

ATC

metronidazole; oral, rectal

1.8

19.5

495

3355

Z3226

NOMESCO Finland

Physiotherapist

2.1

19.5

240

1249

W01

ICD-10 Finland

Fall on same level from slipping, tripping and stumbling

1.9

19.5

350

2112

J45.9

ICD-10 Finland

Asthma, unspecified

2.2

19.5

219

1094

R03DC03

ATC

montelukast; oral

2.2

19.4

214

1058

WYA05

NOMESCO Finland

Emergency visit or other similar visit involving procedures

1.7

19.3

587

4201

SPAT1249

SPAT

Treatment-related counselling outside office

1.8

18.9

473

3179

N04BC05

ATC

pramipexole; oral

3.2

18.8

103

341

XA402

NOMESCO Finland

ENMG

8.2

18.8

R52.1

ICD-10 Finland

Chronic intractable pain

70.9

18.7

K30

ICD-10 Finland

Functional dyspepsia

2.6

18.6

143

588

NBG15

NOMESCO Finland

Acromioplastia, arthroscopic

3.4

18.6

288

M46.1

ICD-10 Finland

Sacroiliitis, not elsewhere classified

192.6

18.6

X59

ICD-10 Finland

Exposure to unspecified factor

2.1

18.6

225

1159

R07.3

ICD-10 Finland

Other chest pain

2.8

18.4

124

471

RF210

NOMESCO Finland

5.6

18.4

100

G54.0

ICD-10 Finland

Brachial plexus disorders

7.9

18.4

R53

ICD-10 Finland

Malaise and fatigue

2.0

18.2

248

1342

C07AB07

ATC

bisoprolol; oral

1.7

18.0

546

3875

SPAT1212

SPAT

Extensive examination of musculoskeletal system

2.9

18.0

112

404

Z50.8

ICD-10 Finland

Care involving use of other rehabilitation procedures

3.1

18.0

102

346

K59.09

ICD-10 Finland

Constipation, unspecified

3.5

17.8

254

XF600

NOMESCO Finland

Bloodpressure measurement

3.2

17.8

315

M96.1

ICD-10 Finland

Postlaminectomy syndrome, not elsewhere classified

+∞

17.7

A03FA01

ATC

metoclopramide; systemic, rectal

2.0

17.7

271

1532

F32.10

ICD-10 Finland

Moderate depressive episode without somatic syndrome

3.0

17.7

108

386

G55.1*M51.9

ICD-10 Finland

Nerve root and plexus compressions in intervertebral disc disorders (M50-M51+)

96.3

17.6

9212

FHL

Other posterior root decompression surgery (eg laminectomy, Gill)

182.3

17.5

WZB00

NOMESCO Finland

Telephone receipt or other advice

1.8

17.5

342

2110

N02AB03

ATC

fentanyl; nasal, sublingual, transdermal

4.4

17.5

151

M19.0

ICD-10 Finland

Primary arthrosis of other joints

2.7

17.5

125

491

J01CR02

ATC

amoxicillin and beta-lactamase inhibitor; systemic

1.7

17.5

606

4459

SPAT1153

SPAT

Removal of sutures

1.8

17.4

372

2364

N06AB10

ATC

escitalopram; oral

2.0

17.4

247

1355

Z03.9

ICD-10 Finland

Observation for suspected disease or condition, unspecified

2.1

17.3

204

1036

A03FA02

ATC

cisapride; oral, rectal

2.8

17.2

114

430

J02AC01

ATC

fluconazole; systemic

1.7

17.2

504

3529

M17.1

ICD-10 Finland

Other primary gonarthrosis

2.0

17.1

251

1396

K21.9

ICD-10 Finland

Gastro-oesophageal reflux disease without oesophagitis

2.6

17.1

129

522

L17

ICPC

Foot/toe symptom/complaint

1.9

17.1

293

1725

P01

ICPC

Feeling anxious/nervous/tense

2.7

17.1

120

468

R20.2

ICD-10 Finland

Paraesthesia of skin

3.4

17.1

263

N39.4

ICD-10 Finland

Other specified urinary incontinence

2.8

17.0

113

426

B01AB05

ATC

enoxaparin; parenteral

1.8

17.0

361

2288

ZXE20

NOMESCO Finland

More than three and less than five hours

2.3

16.9

171

807

TPH04

NOMESCO Finland

Cathetrisation of vein

2.0

16.9

249

1387

X58

ICD-10 Finland

Exposure to other specified factors

2.3

16.8

171

812

M50.9

ICD-10 Finland

Cervical disc disorder, unspecified

64.2

16.8

7221A

ICD-9 Finland

Intervertebral disk disorders, Displacement of thoracic or lumbar intervertebral disk without myelopathy

+∞

16.7

M47.1

ICD-10 Finland

Other spondylosis with myelopathy

+∞

16.7

NAG66

NOMESCO Finland

Posterior interbody fusion of lumbar spine, 2 vertebrae

+∞

16.7

SHB00

NOMESCO Finland

Prepation and fitting of bite rail to mouth

2.6

16.5

126

514

M51.2

ICD-10 Finland

Other specified intervertebral disc displacement

172.0

16.5

L12

ICPC

Hand/finger symptom/complaint

2.3

16.4

170

814

C01DA08

ATC

isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal

2.0

16.4

252

1425

R06AE07

ATC

cetirizine; oral

1.7

16.3

534

3845

J01DA09

ATC

[U] cefadroxil; inhalant, oral

1.8

16.2

336

2108

F41.9

ICD-10 Finland

Anxiety disorder, unspecified

2.8

16.2

106

394

A02BX02

ATC

sucralfate; oral

3.8

16.2

188

SFA10

NOMESCO Finland

Fillning on one surface of tooth

1.6

16.2

626

4712

ZXA00

NOMESCO Finland

Right side

1.8

16.2

331

2069

SAA01

NOMESCO Finland

Simple examination of mouth

1.6

16.1

833

6770

WZC00

NOMESCO Finland

Planning of intervention or health care consultation

1.7

16.1

395

2612

J01FA09

ATC

clarithromycin; systemic

1.7

16.1

392

2585

SPAT1240

SPAT

Therapeutic discussion

2.5

16.0

130

551

Z3231

NOMESCO Finland

Registered nurse

1.8

15.9

335

2112

WX002

NOMESCO Finland

Sedation and analgesia

1.9

15.9

254

1456

FN1AC

NOMESCO Finland

Angiography of heart and/or coronary arteries

2.0

15.9

236

1313

C01DA02

ATC

glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal

2.0

15.9

223

1214

N06AA10

ATC

nortriptyline; systemic

6.9

15.8

L02

ICPC

Back symptom/complaint

2.8

15.8

108

414

PH2AE

NOMESCO Finland

Ultrasound examination of lower leg veins

2.4

15.8

144

647

S06.0

ICD-10 Finland

Concussion

2.5

15.7

125

524

N05BA04

ATC

oxazepam; oral

1.8

15.7

293

1771

M01AH03

ATC

valdecoxib; oral

3.2

15.6

282

K58.0

ICD-10 Finland

Irritable bowel syndrome with diarrhoea

3.2

15.4

261

SPAT1260

SPAT

Consultation of another employee

2.0

15.3

208

1116

Z50.9

ICD-10 Finland

Care involving use of rehabilitation procedure, unspecified

4.4

15.3

133

JN3BD

NOMESCO Finland

Extensive abdominal CT

2.4

15.3

138

615

M75.0

ICD-10 Finland

Adhesive capsulitis of shoulder

3.3

15.2

242

ZXD05

NOMESCO Finland

Urgent procedure

1.7

15.1

370

2437

M77.1

ICD-10 Finland

Lateral epicondylitis

2.9

15.1

351

EB1AA

NOMESCO Finland

Tooth X-ray examination

1.6

15.1

638

4879

J01EA01

ATC

trimethoprim; systemic

1.8

15.0

312

1954

XF400

NOMESCO Finland

ECG with 12 standard connections

2.0

15.0

202

1084

C01DA14

ATC

isosorbide mononitrate; oral

2.1

14.9

173

869

Z50.1

ICD-10 Finland

Other physical therapy

3.5

14.9

202

NE1BG

NOMESCO Finland

Pelvic, hip and femur MRI examination with high intensity magnet

5.6

14.9

N05AH04

ATC

quetiapine; oral

2.1

14.8

191

1003

J01EE02

ATC

sulfadiazine and trimethoprim; systemic

1.8

14.8

306

1910

A02BC04

ATC

rabeprazole; oral

2.6

14.8

109

437

206

Kela drug reimbursment

Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease

2.0

14.7

192

1015

J01FF01

ATC

clindamycin; systemic

1.8

14.7

318

2014

AB5BT

NOMESCO Finland

Blockage of nerv root with X-ray guidance

+∞

14.6

ABC30

NOMESCO Finland

Decompression of cervical nerve roots

151.6

14.5

G55.2*M47.9

ICD-10 Finland

Nerve root and plexus compressions in spondylosis

36.5

14.5

SAA02

NOMESCO Finland

Basic examination of mouth

1.6

14.2

744

5965

SPAT1283

SPAT

Restricted health certificate

2.0

14.2

196

1057

R01BA52

ATC

pseudoephedrine, combinations; oral

1.7

14.1

378

2550

J01FA10

ATC

azithromycin; systemic

1.6

14.0

675

5297

C03CA01

ATC

furosemide; systemic

1.7

14.0

315

2015

NF1AA

NOMESCO Finland

Hip X-ray examination

2.6

13.9

104

420

R4110

NOMESCO Finland

Physiotherapy

1.8

13.9

304

1928

R35

ICD-10 Finland

Polyuria

3.1

13.8

254

A02BA04

ATC

nizatidine; systemic

2.6

13.8

106

434

XKC03

NOMESCO Finland

Water cystometry

4.3

13.8

123

S18

ICPC

Laceration/cut

1.6

13.6

468

3365

ABD30

NOMESCO Finland

Implantation of spinal stimulation device

14.9

13.6

00000

ICD-8 Finland

7.3

13.6

72899

ICD-8 Finland

Vertebrogenic pain syndrome, Other and unspecified

+∞

13.6

NAG63

NOMESCO Finland

Posterior fusion of lumbar spine with fixation, more than 3 vertebraea

+∞

13.6

R01AD58

ATC

fluticasone, combinations; inhalant, nasal

1.8

13.5

243

1442

NG1AA

NOMESCO Finland

Knee X-ray examination without contrast

2.2

13.4

143

691

K57.3

ICD-10 Finland

Diverticular disease of large intestine without perforation or abscess

2.0

13.2

196

1084

R05FA02

ATC

opium derivatives and expectorants; systemic

1.6

13.2

476

3460

XKD00

NOMESCO Finland

Uroflowmetry

2.1

13.1

157

800

UDH02

NOMESCO Finland

Rhinopharyngoscopy

2.8

13.1

333

M03BX01

ATC

baclofen; systemic

8.4

13.1

R11

ICD-10 Finland

Nausea and vomiting

2.6

13.0

397

M17.9

ICD-10 Finland

Gonarthrosis, unspecified

2.3

13.0

129

606

J32.0

ICD-10 Finland

Chronic maxillary sinusitis

2.6

12.9

388

Y83

ICD-10 Finland

Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure

2.6

12.9

381

SPAT1310

SPAT

Counselling related to known health issue

1.7

12.9

359

2435

M16.1

ICD-10 Finland

Other primary coxarthrosis

2.3

12.8

123

569

H05BA01

ATC

calcitonin (salmon synthetic); nasal, parenteral

4.2

12.8

118

M75.9

ICD-10 Finland

Shoulder lesion, unspecified

3.5

12.7

179

AA1CG

NOMESCO Finland

Extensive MRI examination of brain with high intensity magnet

2.5

12.7

100

415

NE1CG

NOMESCO Finland

Pelvic, hip and femur extensive MRI examination with high intensity magnet

5.9

12.7

N03AX09

ATC

lamotrigine; oral

3.5

12.6

175

Z03.3

ICD-10 Finland

Observation for suspected nervous system disorder

2.9

12.6

265

SPAT1254

SPAT

Administration of medicine

2.0

12.6

163

858

ACC51

NOMESCO Finland

Release of median nerve

2.8

12.5

307

SPAT1222

SPAT

Counselling/guidance promoting independent living

2.0

12.5

170

910

UJD02

NOMESCO Finland

Gastroscopy

3.0

12.3

251

M01AE01

ATC

ibuprofen; systemic, rectal

1.7

12.3

1088

9760

A12AX

ATC

Calcium, combinations with vitamin D and/or other drugs

1.6

12.2

378

2629

R01AD12

ATC

fluticasone furoate; nasal

1.6

12.2

343

2324

T81.4

ICD-10 Finland

Infection following a procedure, not elsewhere classified

2.2

12.2

123

579

L13

ICPC

Hip symptom/complaint

2.0

12.1

167

899

R03BA02

ATC

budesonide; inhalant

1.8

12.1

211

1237

ACC59

NOMESCO Finland

Decompression and freeing of adhesions of peripheral nerve: other or unspecified

3.2

12.0

204

S01XA20

ATC

artificial tears and other indifferent preparations; ophthalmic

1.6

12.0

475

3509

R05

ICPC

Cough

1.8

12.0

243

1495

SPAT1256

SPAT

Intramuscular and subcutaneous injection

1.6

12.0

472

3485

TAB00

NOMESCO Finland

Lumbar puncture

3.2

11.9

195

H04.10

ICD-10 Finland

Dry eye syndrome

2.2

11.9

121

573

ZXM10

NOMESCO Finland

Intraoperative use of conventional X-ray imaging

3.2

11.8

201

R05FB02

ATC

cough suppressants and expectorants

1.6

11.8

443

3233

K59.0

ICD-10 Finland

Constipation

3.0

11.7

236

R55

ICD-10 Finland

Syncope and collapse

2.2

11.7

121

578

N05CD07

ATC

temazepam; oral

2.0

11.7

149

778

R5110

NOMESCO Finland

Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it

2.1

11.7

146

754

G55.1

ICD-10 Finland

Nerve root and plexus compressions in intervertebral disc disorders

16.6

11.7

F51.0

ICD-10 Finland

Nonorganic insomnia

2.0

11.7

146

756

H02AB04

ATC

methylprednisolone; systemic

1.9

11.7

173

957

R51.81

ICD-10 Finland

Facial pain NOS

4.9

11.6

A03CA02

ATC

clidinium and psycholeptics; oral

2.8

11.6

268

C07AA05

ATC

propranolol; systemic

1.8

11.6

217

1303

SPAT1255

SPAT

Intravenous administration of medicine

2.6

11.5

329

T84.0

ICD-10 Finland

Mechanical complication of internal joint prosthesis

3.9

11.5

125

M89.0

ICD-10 Finland

Algoneurodystrophy

10.1

11.5

N06AX03

ATC

mianserin; oral

3.1

11.5

220

7210A

ICD-9 Finland

Spondylosis and allied disorders, Cervical spondylosis without myelopathy

+∞

11.5

7228C

ICD-9 Finland

Intervertebral disk disorders, Postlaminectomy syndrome[SYNDROMA LUMBOSACRALE POSTLAMINECTOMIAM]

+∞

11.5

7244A

ICD-9 Finland

Other and unspecified disorders of back, Thoracic or lumbosacral neuritis or radiculitis, unspecified

+∞

11.5

7213A

ICD-9 Finland

Spondylosis and allied disorders, Lumbosacral spondylosis without myelopathy

+∞

11.5

7240B

ICD-9 Finland

Other and unspecified disorders of back, Spinal stenosis, other than cervical[STENOSIS CANALIS SPINALIS LUMBOSACRALIS]

+∞

11.5

H02AB07

ATC

prednisone; oral

1.9

11.5

175

978

WX308

NOMESCO Finland

Sacral anesthesy

121.0

11.4

G83.4

ICD-10 Finland

Cauda equina syndrome

121.0

11.4

WZA90

NOMESCO Finland

Other doctors statement

1.7

11.4

246

1541

SPAT1216

SPAT

Assessment of functional ability

1.9

11.4

164

897

F32.11

ICD-10 Finland

Moderate depressive episode with somatic syndrome

4.3

11.4

NA2AA

NOMESCO Finland

Thoracal spine X-ray examination without contrast

5.3

11.4

78551

ICD-8 Finland

Symptoms referable to abdomen and lower gastro-intestinal tract, Symptomata abdominalis acuta NUD

3.7

11.3

137

TAC99

NOMESCO Finland

Other blockade for chronic pain

15.2

11.3

ZXE00

NOMESCO Finland

One hour or less

1.5

11.3

457

3384

R4120

NOMESCO Finland

Occupational therapy

2.6

11.2

311

JN3AA

NOMESCO Finland

Abdominal X-ray examination without contrast

3.1

11.2

204

SHA02

NOMESCO Finland

Correction of physiology of bite - basic therapy visit

2.6

11.1

331

G43.9

ICD-10 Finland

Migraine, unspecified

2.9

11.1

244

J01FA15

ATC

telithromycin; oral

2.1

11.1

129

649

M76.6

ICD-10 Finland

Achilles tendinitis

3.9

11.0

115

Z01.5

ICD-10 Finland

Diagnostic skin and sensitization tests

2.2

11.0

111

524

S30.0

ICD-10 Finland

Contusion of lower back and pelvis

3.5

11.0

146

N01

ICPC

Headache

2.3

11.0

106

491

D07AD01

ATC

clobetasol; topical

1.8

11.0

189

1104

S33.6

ICD-10 Finland

Sprain and strain of sacroiliac joint

43.7

10.9

J46

ICD-10 Finland

Status asthmaticus

4.3

10.9

ZZH21

NOMESCO Finland

Graft of patients own bone, small pieces

6.0

10.9

J01MA12

ATC

levofloxacin; systemic

1.8

10.9

206

1238

NA1AD

NOMESCO Finland

Cervical spine CT examination

3.7

10.9

132

K02.1

ICD-10 Finland

Caries of dentine

1.5

10.8

633

5070

NA2CG

NOMESCO Finland

Thoracal spine extensive MRI examination with high intensity magnet

10.7

10.8

S46.0

ICD-10 Finland

Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder

2.4

10.8

394

N05BA12

ATC

alprazolam; oral

2.1

10.8

125

628

M01AX05

ATC

glucosamine; oral

1.7

10.8

223

1380

J18.9

ICD-10 Finland

Pneumonia, unspecified

1.7

10.7

252

1619

Z01.0

ICD-10 Finland

Examination of eyes and vision

1.9

10.7

173

987

I10

ICD-10 Finland

Essential (primary) hypertension

1.5

10.7

635

5096

N06AB03

ATC

fluoxetine; oral

1.9

10.7

151

821

KC1EE

NOMESCO Finland

Ultrasound measurement of residual urine

2.1

10.7

122

607

SFA00

NOMESCO Finland

Small filling

2.0

10.7

147

791

FM1EE

NOMESCO Finland

Extensive structural and functional ultrasound examination of heart

1.7

10.6

228

1425

M17.0

ICD-10 Finland

Primary gonarthrosis, bilateral

2.0

10.6

146

786

C08DA01

ATC

verapamil; systemic

3.1

10.6

184

M19.1

ICD-10 Finland

Post-traumatic arthrosis of other joints

4.0

10.5

105

203

Kela drug reimbursment

Chronic asthma and similar chronic obstructive pulmonary diseases

1.7

10.5

216

1333

R60.0

ICD-10 Finland

Localized oedema

2.1

10.5

123

621

Z87.1

ICD-10 Finland

Personal history of diseases of the digestive system

1.5

10.5

497

3799

H57.1

ICD-10 Finland

Ocular pain

4.0

10.4

106

I25.1

ICD-10 Finland

Atherosclerotic heart disease

1.8

10.4

212

1302

7242A

ICD-9 Finland

Other and unspecified disorders of back, Lumbago

+∞

10.4

NA7BT

NOMESCO Finland

Injection to spinal facet joint with radiological guidance

+∞

10.4

R30.0

ICD-10 Finland

Dysuria

3.5

10.4

142

K04.1

ICD-10 Finland

Necrosis of pulp

2.1

10.4

122

614

W00

ICD-10 Finland

Fall on same level involving ice and snow

2.1

10.4

128

657

W19

ICD-10 Finland

Unspecified fall

2.2

10.4

107

512

M02AA10

ATC

ketoprofen; topical

1.8

10.3

185

1089

M67.4

ICD-10 Finland

Ganglion

2.5

10.3

351

TAB20

NOMESCO Finland

Epidural puncture

10.7

10.3

SFA20

NOMESCO Finland

Filling on two surfaces of tooth

1.5

10.3

647

5236

R01AD08

ATC

fluticasone; nasal

1.6

10.3

331

2308

SPAT1148

SPAT

Treatment of chronic ulcer or burn

1.9

10.2

148

811

ZXA10

NOMESCO Finland

Bilateral

1.7

10.2

208

1281

C07AB02

ATC

metoprolol; systemic

1.7

10.1

228

1442

K58.9

ICD-10 Finland

Irritable bowel syndrome without diarrhoea

3.4

10.1

140

G56.2

ICD-10 Finland

Lesion of ulnar nerve

4.2

10.1

D01

ICPC

Abdominal pain/cramps general

2.1

10.1

111

544

G04BD04

ATC

oxybutynin; oral, transdermal

2.6

10.1

279

B01AC04

ATC

clopidogrel; oral

1.9

10.1

155

869

50099

ICD-8 Finland

Hypertrophy of tonsils and adenoids

2.0

10.0

124

640

NB1AA

NOMESCO Finland

Shoulder X-ray examination without contrast

2.5

10.0

325

C10AX09

ATC

ezetimibe; oral

2.1

10.0

117

590

SAA03

NOMESCO Finland

Extended examination of mouth

1.5

10.0

421

3128

P03

ICPC

Feeling depressed

2.3

9.9

423

R05DA20

ATC

opium alkaloids and derivatives - combinations

1.6

9.9

291

1982

R96

ICPC

Asthma

2.2

9.9

101

481

K10.3

ICD-10 Finland

Alveolitis of jaws

2.9

9.9

211

R41.8

ICD-10 Finland

Other and unspecified symptoms and signs involving cognitive functions and awareness

2.2

9.8

100

472

SFA30

NOMESCO Finland

Filling on tree or more surfaces of tooth

1.5

9.8

453

3429

J45.0

ICD-10 Finland

Predominantly allergic asthma

2.2

9.8

462

F43.1

ICD-10 Finland

Post-traumatic stress disorder

4.9

9.8

A02BB01

ATC

misoprostol; oral

9.6

9.8

H81.1

ICD-10 Finland

Benign paroxysmal vertigo

2.1

9.8

111

552

G43.1

ICD-10 Finland

Migraine with aura [classical migraine]

2.6

9.8

279

R05

ICD-10 Finland

Cough

1.7

9.7

206

1282

R13

ICD-10 Finland

Dysphagia

2.5

9.7

309

Z03.89

ICD-10 Finland

Observation for other suspected diseases and conditions

2.0

9.7

135

729

1410

FHL

Laparoscopy

3.3

9.6

141

M75.8

ICD-10 Finland

Other shoulder lesions

3.6

9.6

120

SHA01

NOMESCO Finland

Correction of physiology of bite - simple therapy visit

2.0

9.5

118

608

R52.0

ICD-10 Finland

Acute pain

3.8

9.4

106

NA3CM

NOMESCO Finland

Lumbar spine extensive MRI examination with 3 Tesla magnet

100.7

9.4

M35.0

ICD-10 Finland

Sicca syndrome [Sjögren]

4.6

9.4

R03AC03

ATC

terbutaline; inhalant

1.8

9.4

164

960

WX290

NOMESCO Finland

Other blockade of nerve

1.5

9.4

474

3643

F32.2

ICD-10 Finland

Severe depressive episode without psychotic symptoms

2.5

9.4

284

RF313

NOMESCO Finland

+∞

9.4

M48.9

ICD-10 Finland

Spondylopathy, unspecified

+∞

9.4

M47.8

ICD-10 Finland

Other spondylosis

+∞

9.4

F33.10

ICD-10 Finland

Recurrent depression, moderate episode without somatic syndrome

2.7

9.4

241

ZXA05

NOMESCO Finland

Left side

1.6

9.3

281

1920

M01AB01

ATC

indometacin; systemic, rectal

2.3

9.3

384

F33.2

ICD-10 Finland

Recurrent depressive disorder, current episode severe without psychotic symptoms

2.8

9.3

210

M01AG02

ATC

tolfenamic acid; oral, rectal

1.8

9.3

183

1110

R06AE09

ATC

levocetirizine; oral

1.8

9.3

166

977

AN1

Coronary angiography

2.0

9.3

124

660

ABD32

NOMESCO Finland

Implantation of temporary spinal stimulation device

13.8

9.2

AA1BG

NOMESCO Finland

Standard MRI examination of brain with high intensity magnet

2.2

9.2

427

A02BA03

ATC

famotidine; systemic

3.1

9.2

163

I84.2

ICD-10 Finland

Internal hemorrhoids without complication

2.2

9.2

428

R03BA05

ATC

fluticasone; inhalant

1.7

9.1

206

1303

S93.4

ICD-10 Finland

Sprain and strain of ankle

2.1

9.1

106

532

K08.80

ICD-10 Finland

Toothache NOS

2.2

9.1

469

M76.8

ICD-10 Finland

Other enthesopathies of lower limb, excluding foot

7.1

9.0

Z01.2

ICD-10 Finland

Dental examination

1.5

9.0

443

3386

Z02.7

ICD-10 Finland

Issue of medical certificate

2.5

9.0

280

R06AX27

ATC

desloratadine; oral

1.6

9.0

296

2069

G04CA02

ATC

tamsulosin; oral

1.7

8.9

186

1151

J01CA04

ATC

amoxicillin; systemic

1.5

8.9

943

8353

ZXE13

NOMESCO Finland

Procedure duration 90 to 119 minutes

3.2

8.9

139

M79.9

ICD-10 Finland

Soft tissue disorder, unspecified

12.6

8.9

A07AA02

ATC

nystatin; oral

2.4

8.8

322

M79.2

ICD-10 Finland

Neuralgia and neuritis, unspecified

4.6

8.8

SPAT1325

SPAT

Vaccination

1.5

8.8

368

2712

WZC10

NOMESCO Finland

Extensive specialist consultion with written report

2.7

8.8

224

N02AJ13

ATC

tramadol and paracetamol; systemic

5.2

8.8

M23.2

ICD-10 Finland

Derangement of meniscus due to old tear or injury

1.9

8.8

126

686

GD1QA

NOMESCO Finland

Supine thorax X-ray examination

1.8

8.8

150

872

NA7CG

NOMESCO Finland

Spine and spinal cord extensive MRI examination with high intensity magnet

9.5

8.8

R09

ICPC

Sinus symptom/complaint

2.1

8.8

450

M01AE51

ATC

ibuprofen, combinations; systemic

5.4

8.8

NB1AE

NOMESCO Finland

Shoulder ultrasound examination

5.7

8.8

A28

ICPC

Limited function/disability NOS

1.8

8.7

148

858

N39.0

ICD-10 Finland

Urinary tract infection, site not specified

1.8

8.7

151

879

R03BB04

ATC

tiotropium bromide; inhalant

2.0

8.7

104

530

T78.4

ICD-10 Finland

Allergy, unspecified

2.8

8.7

203

K07.60

ICD-10 Finland

Snapping jaw

2.8

8.7

193

NA3BA

NOMESCO Finland

Lumbar spine extensive X-ray examination without contrast

50.3

8.7

TEW99

NOMESCO Finland

Other minor procedure in surgery of teeth, jaws, mouth and pharynx

2.8

8.7

204

NH3AA

NOMESCO Finland

Foot and toes X-ray examination

2.1

8.6

469

C05AA08

ATC

fluocortolone; rectal, topical

1.8

8.6

162

970

LC2BE

NOMESCO Finland

Transvaginal ultrasound examination of uterus, parametria and lower abdomen

1.5

8.6

300

2122

N05CF02

ATC

zolpidem; oral

1.7

8.6

200

1277

ZZH40

NOMESCO Finland

Substitute of bone

8.3

8.6

6421

FHL

Appendicectomy

2.4

8.6

325

I49.9

ICD-10 Finland

Cardiac arrhythmia, unspecified

1.9

8.6

128

708

L83

ICPC

Neck syndrome

10.1

8.5

J05AB01

ATC

aciclovir; systemic

1.6

8.5

232

1545

R02

ICPC

Shortness of breath/dyspnoea

1.9

8.5

122

664

G62.9

ICD-10 Finland

Polyneuropathy, unspecified

3.7

8.5

N30.1

ICD-10 Finland

Interstitial cystitis (chronic)

6.0

8.5

NA7DG

NOMESCO Finland

Spine and spinal cord very extensive MRI examination with high intensity magnet

7.4

8.5

R50.9

ICD-10 Finland

Fever, unspecified

1.8

8.5

142

821

F33.9

ICD-10 Finland

Recurrent depressive disorder, unspecified

2.9

8.4

172

N03A

ATC

ANTIEPILEPTICS

90.6

8.4

T81.8

ICD-10 Finland

Other complications of procedures, not elsewhere classified

4.2

8.4

E66.01

ICD-10 Finland

Obesity due to excess calories

2.2

8.4

411

C03EA01

ATC

hydrochlorothiazide and potassium-sparing agents; oral

1.7

8.4

178

1107

I25.9

ICD-10 Finland

Chronic ischaemic heart disease, unspecified

2.0

8.4

103

529

J01DA08

ATC

[U] cefaclor; oral

1.9

8.4

119

648

KMAK

NOMESCO Finland

1.4

8.4

580

4714

71312

ICD-8 Finland

Osteo-arthritis and allied conditions, Spondylarthritis lumbalis sive lumbosacralis

+∞

8.3

7200A

ICD-9 Finland

Ankylosing spondylitis and other inflammatory spondylopathies, Ankylosing spondylitis

+∞

8.3

SPAT1305

SPAT

Counselling and guidance related to physical exercise

2.0

8.3

101

518

R51

ICD-10 Finland

Headache

2.5

8.3

247

M16.0

ICD-10 Finland

Primary coxarthrosis, bilateral

2.4

8.3

316

G43.0

ICD-10 Finland

Migraine without aura [common migraine]

2.7

8.3

214

1220

FHL

Arthroscopy

2.9

8.3

175

JN3AE

NOMESCO Finland

Abdominal ultrasound examination

1.8

8.3

139

804

S13.4

ICD-10 Finland

Sprain and strain of cervical spine

3.2

8.3

130

N31.2

ICD-10 Finland

Flaccid neuropathic bladder, not elsewhere classified

7.1

8.3

M01AE52

ATC

naproxen and esomeprazole; oral

3.2

8.2

136

SPAT1312

SPAT

General health counselling

1.5

8.2

340

2493

C10AA07

ATC

rosuvastatin; oral

1.6

8.2

243

1648

M01AB08

ATC

etodolac; oral

2.3

8.2

352

N02CC01

ATC

sumatriptan; nasal, systemic, rectal

1.8

8.2

138

797

SPAT1250

SPAT

Comprehensive monitoring of chronic illness

1.5

8.2

285

2013

C10AA01

ATC

simvastatin; oral

1.4

8.2

446

3461

F32.00

ICD-10 Finland

Mild depressive episode without somatic syndrome

2.9

8.2

164

NB1CG

NOMESCO Finland

Shoulder and humerus extensive MRI examination with high intensity magnet

4.2

8.1

K59.1

ICD-10 Finland

Functional diarrhoea

2.6

8.1

227

R03AC13

ATC

formoterol; inhalant

2.6

8.1

227

NE1AA

NOMESCO Finland

Pelvis X-ray examination

2.4

8.1

284

I20.09

ICD-10 Finland

Unstable angina

2.5

8.1

257

NGA30

NOMESCO Finland

Exploration of knee joint, arthroscopic

2.5

8.1

257

NGD05

NOMESCO Finland

Partial excision of meniscus of knee, arthroscopic

1.8

8.1

128

726

GD1UA

NOMESCO Finland

Thorax X-ray examination outside radiological department

1.8

8.0

150

894

SPAT1220

SPAT

Assessment of need for rehabilitation and/or rehabilitation plan

2.3

8.0

319

-1

NOMESCO Finland

1.5

7.9

354

2636

78559

ICD-8 Finland

Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD

2.9

7.9

162

M22.4

ICD-10 Finland

Chondromalacia patellae

3.2

7.9

129

K29.7

ICD-10 Finland

Gastritis, unspecified

3.0

7.9

146

Z2446

NOMESCO Finland

Social worker

2.3

7.9

334

N39.3

ICD-10 Finland

Stress incontinence

2.1

7.9

443

NH1AA

NOMESCO Finland

Ankle X-ray examination without contrast

2.2

7.9

347

SPAT1252

SPAT

Overall medication plan or its review

2.2

7.9

369

G44.0

ICD-10 Finland

Cluster headache syndrome

6.1

7.9

M03BB53

ATC

chlorzoxazone, combinations excl. psycholeptics; oral

5.7

7.8

A01AB09

ATC

miconazole; local oral

2.0

7.8

103

543

A07EC01

ATC

sulfasalazine; oral, rectal

2.1

7.8

396

L84

ICPC

Back syndrome without radiat pain

3.1

7.8

136

F41.2

ICD-10 Finland

Mixed anxiety and depressive disorder

2.1

7.8

397

WX404

NOMESCO Finland

Intravenous generell anesthesy

1.6

7.8

233

1586

K04.0

ICD-10 Finland

Pulpitis

1.9

7.8

105

563

ZY020

NOMESCO Finland

Telephone, letter or other consultation without direct patient contact

2.2

7.7

355

Z71.3

ICD-10 Finland

Dietary counselling and surveillance

2.5

7.7

232

G82.2

ICD-10 Finland

Paraplegia, unspecified

15.1

7.7

N1302

NOMESCO Finland

45.2

7.7

N07BC02

ATC

methadone; systemic

45.2

7.7

M41.2

ICD-10 Finland

Other idiopathic scoliosis

45.2

7.7

Z76.9

ICD-10 Finland

Person encountering health services in unspecified circumstances

2.2

7.7

344

NB1BG

NOMESCO Finland

Shoulder and humerus MRI examination with high intensity magnet

4.6

7.7

J45.8

ICD-10 Finland

Mixed asthma

3.1

7.7

132

J01CA08

ATC

pivmecillinam; oral

1.4

7.7

463

3652

R03AK06

ATC

salmeterol and fluticasone; inhalant

1.8

7.7

144

863

Z01.9

ICD-10 Finland

Special examination, unspecified

2.4

7.6

253

D07AC01

ATC

betamethasone; topical

1.5

7.6

370

2795

SPAT1281

SPAT

Other administrative function

2.1

7.6

448

J45.1

ICD-10 Finland

Nonallergic asthma

2.2

7.6

338

M76.3

ICD-10 Finland

Iliotibial band syndrome

18.5

7.6

GD1PA

NOMESCO Finland

X-ray examination of the lungs in one projection

2.1

7.6

423

ZXE11

NOMESCO Finland

Procedure duration 60 to 89 minutes

2.3

7.6

286

NBF25

NOMESCO Finland

Operation for humeroscapular osteochondritis, arthroscopic

3.7

7.6

M51

ICD-10 Finland

Other intervertebral disc disorders

25.2

7.6

K29.5

ICD-10 Finland

Chronic gastritis, unspecified

3.2

7.6

117

M76.0

ICD-10 Finland

Gluteal tendinitis

5.5

7.5

N06AB06

ATC

sertraline; oral

1.9

7.5

118

665

2968A

ICD-9 Finland

Affective psychoses, Manic-depressive psychosis, other and unspecified

5.8

7.5

S82.6

ICD-10 Finland

Fracture of lateral malleolus

2.3

7.5

308

N06AA12

ATC

doxepin; systemic

2.4

7.5

268

XKD06

NOMESCO Finland

Physiologic investigation of micturition

3.3

7.5

112

62699

ICD-8 Finland

Disorders of menstruation, Other

3.2

7.4

113

8306

FHL

Hysterectomy (related to abortion 8516, prolapse correction 8436)

2.8

7.4

158

NBA30

NOMESCO Finland

Exploration of joint of shoulder or upper arm, arthroscopic

3.3

7.4

108

ICD-10 Finland

3.4

7.4

103

TPH07

NOMESCO Finland

Cathetrisation of artery

1.9

7.4

109

601

SPAT1156

SPAT

Guidance concerning treatment of rash and skin

1.7

7.3

139

833

WYA30

NOMESCO Finland

Preparations for expected poor cooperation

2.0

7.3

480

FB1BD

NOMESCO Finland

Extensive CT examination of arteria pulmonalis

2.1

7.3

378

R10.0

ICD-10 Finland

Acute abdomen

3.1

7.3

120

N30.0

ICD-10 Finland

Acute cystitis

1.7

7.3

142

857

M47

ICD-10 Finland

Spondylosis

10.9

7.3

7241A

ICD-9 Finland

Other and unspecified disorders of back, Pain in thoracic spine

+∞

7.3

NA3BM

NOMESCO Finland

Lumbar spine MRI examination with 3 Tesla magnet

+∞

7.3

7225A

ICD-9 Finland

Intervertebral disk disorders, Degeneration of thoracic or lumbar intervertebral disk[DEGENERATIO DISCI INTERVERTEBRALIS THORAC SEU LUMB]

+∞

7.3

TAD08

NOMESCO Finland

Sympathetic block on sacral Level

+∞

7.3

71310

ICD-8 Finland

Osteo-arthritis and allied conditions, Spondylarthritis cervicalis

+∞

7.3

7865A

ICD-9 Finland

Symptoms involving respiratory system and other chest symptoms, Chest pain

5.0

7.3

Y0899

ICD-8 Finland

Investigation of musculoskeletal system

9.4

7.3

JN1AE

NOMESCO Finland

Ultrasound examination of upper part of abdomen

2.0

7.3

473

N30.9

ICD-10 Finland

Cystitis, unspecified

2.3

7.3

279

QX2XE

NOMESCO Finland

Ultrsound examination of soft tissue not elsewhere classified

3.4

7.3

M15.0

ICD-10 Finland

Primary generalized (osteo)arthrosis

3.1

7.2

127

UJF45

NOMESCO Finland

Flexible sigmoidoscopy with biopsy

2.0

7.2

466

G04CA01

ATC

alfuzosin; oral

2.0

7.2

481

R03AK07

ATC

formoterol and budesonide; inhalant

1.6

7.2

205

1378

E66.8

ICD-10 Finland

Other obesity

2.4

7.2

262

ZY010

NOMESCO Finland

Hospital outpatient

2.5

7.2

215

Z01.4

ICD-10 Finland

Gynaecological examination (general)(routine)

1.6

7.2

174

1122

W10

ICD-10 Finland

Fall on and from stairs and steps

2.5

7.2

234

TAW99

NOMESCO Finland

Other minor neurosurgical procedure

30.2

7.1

C10AA05

ATC

atorvastatin; oral

1.4

7.1

383

2948

NA1EA

NOMESCO Finland

Cervical spine X-ray examination with flexion

6.6

7.1

NGF25

NOMESCO Finland

Operation for osteochondritis of knee, arthroscopic

2.2

7.1

343

G45.9

ICD-10 Finland

Transient cerebral ischaemic attack, unspecified

2.1

7.1

392

Z2221

NOMESCO Finland

Medical doctor

1.5

7.1

316

2343

N07CA01

ATC

betahistine; oral

2.1

7.1

393

M03BB52

ATC

chlormezanone, combinations excl. psycholeptics; oral, rectal

3.9

7.1

R1230

NOMESCO Finland

Neuropsychological evaluation of need and possibilities to rehabilitation

6.1

7.1

DMB20

NOMESCO Finland

Functional endoscopic opening of maxillary antrum

2.4

7.1

257

SPAT1262

SPAT

Handing over of treatment supplies

1.6

7.0

183

1201

SFC01

NOMESCO Finland

Adjuvant procedure of filling therapy

1.5

7.0

277

2005

M19.9

ICD-10 Finland

Arthrosis, unspecified

2.8

7.0

159

R00.2

ICD-10 Finland

Palpitations

2.0

7.0

410

R07.0

ICD-10 Finland

Pain in throat

2.2

7.0

303

R5140

NOMESCO Finland

Monitoring the use of the aid

1.8

7.0

110

623

F33.11

ICD-10 Finland

Recurrent depression, moderate episode of somatic syndrome

3.7

7.0

L30.9

ICD-10 Finland

Dermatitis, unspecified

1.6

6.9

176

1145

A07DA03

ATC

loperamide; oral

2.6

6.9

178

P76

ICPC

Depressive disorder

2.3

6.9

285

L29

ICPC

Musculoskeletal sympt/complt other

2.1

6.9

377

M15.9

ICD-10 Finland

Polyarthrosis, unspecified

2.4

6.9

242

L15

ICPC

Knee symptom/complaint

1.6

6.9

209

1423

M70.7

ICD-10 Finland

Other bursitis of hip

3.7

6.9

SCA01

NOMESCO Finland

Simple analysis and advice of nutrition with regard to dentistry

1.5

6.9

284

2072

R03DA04

ATC

theophylline; systemic, rectal

2.3

6.9

266

SDA01

NOMESCO Finland

Simple parodonthologic therapy

1.5

6.9

262

1883

J01DA06

ATC

[U] cefuroxime; systemic

1.6

6.8

163

1045

J20

ICD-10 Finland

Acute bronchitis

1.9

6.8

101

560

RF421

NOMESCO Finland

11.0

6.8

J01MA14

ATC

moxifloxacin; systemic

1.9

6.8

499

N06AB05

ATC

paroxetine; oral

2.1

6.8

337

R33

ICD-10 Finland

Retention of urine

2.1

6.8

337

R03BA01

ATC

beclometasone; inhalant

1.7

6.8

147

918

M02AA15

ATC

diclofenac; topical (antiinflammatory prep., non-steroids for topical use)

2.0

6.8

470

R25.2

ICD-10 Finland

Cramp and spasm

3.8

6.8

R06.5

ICD-10 Finland

Mouth breathing

2.0

6.8

457

H60.9

ICD-10 Finland

Otitis externa, unspecified

2.2

6.8

315

Z46.8

ICD-10 Finland

Fitting and adjustment of other specified devices

3.4

6.8

7819X

ICD-9 Finland

Symptoms involving nervous and musculoskeletal systems, Other symptoms involving nervous and musculoskeletal systems[SYMPTOMATA ALIA SYSTEMATIS NERVORUM ET MUSCULOSCEL]

5.7

6.8

C09CA06

ATC

candesartan; oral

1.5

6.8

227

1583

M50.8

ICD-10 Finland

Other cervical disc disorders

40.2

6.8

NA3SA

NOMESCO Finland

Lumbar spine X-ray examination in standing position

16.8

6.7

Z2445

NOMESCO Finland

Psychologist

2.7

6.7

160

R01AD01

ATC

beclometasone; nasal

1.6

6.7

168

1092

N17

ICPC

Vertigo/dizziness

1.8

6.7

111

638

K05.08

ICD-10 Finland

Another acute gingivitis

3.7

6.7

R5599

NOMESCO Finland

Other rehabilitation service

3.8

6.7

NB2AT

NOMESCO Finland

Intra artrial injection of shoulder with ultrasound guidance

4.9

6.7

UDQ12

NOMESCO Finland

Flexible laryngoscopy

2.3

6.7

253

N71.0

ICD-10 Finland

Acute inflammatory disease of uterus

3.5

6.6

R06.4

ICD-10 Finland

Hyperventilation

3.9

6.6

F32.1

ICD-10 Finland

Moderate depressive episode

2.4

6.6

216

7840A

ICD-9 Finland

Symptoms involving head and neck, Headache

4.8

6.5

R31

ICD-10 Finland

Unspecified haematuria

1.9

6.5

523

C09CA01

ATC

losartan; oral

1.5

6.5

250

1795

F43.22

ICD-10 Finland

Adaptation disorder with mixed anxiety and depression

2.6

6.5

184

4730A

ICD-9 Finland

Chronic sinusitis, Maxillary

4.0

6.5

SPAT1058

SPAT

PEF monitoring instruction

1.9

6.5

451

R07.2

ICD-10 Finland

Precordial pain

3.8

6.5

RF220

NOMESCO Finland

5.4

6.5

XF402

NOMESCO Finland

ECG with work load test

1.8

6.4

107

617

M99.0

ICD-10 Finland

Segmental and somatic dysfunction

70.2

6.4

H03AA01

ATC

levothyroxine sodium; systemic

1.5

6.4

254

1838

NA2AD

NOMESCO Finland

Thoracic spine CT examination

14.4

6.4

E66.9

ICD-10 Finland

Obesity, unspecified

2.9

6.4

131

I49.3

ICD-10 Finland

Ventricular premature depolarization

2.1

6.4

325

C07AA07

ATC

sotalol; systemic

2.6

6.4

169

A06AC51

ATC

ispaghula, combinations; systemic

2.2

6.3

270

A08.4

ICD-10 Finland

Viral intestinal infection, unspecified

3.1

6.3

105

NK4XE

NOMESCO Finland

Joint ultrasound examination not elsewhere classified

2.1

6.3

328

K08.1

ICD-10 Finland

Loss of teeth due to accident, extraction or local periodontal disease

1.8

6.3

101

577

Angiography of the heart and coronary arteries

2.1

6.3

306

G72.9

ICD-10 Finland

Myopathy, unspecified

11.1

6.3

WX320

NOMESCO Finland

Spinalanesthesy

1.5

6.3

230

1636

S80.0

ICD-10 Finland

Contusion of knee

2.1

6.3

356

R10.2

ICD-10 Finland

Pelvic and perineal pain

3.3

6.3

R12

ICD-10 Finland

Heartburn

2.0

6.3

357

2713A

ICD-9 Finland

Disorders of carbohydrate transport and metabolism, Intestinal disaccharidase deficiencies and disaccharide malabsorption[MALABSORPTIO LACTOSI]

18.1

6.3

NA3DG

NOMESCO Finland

Lumbar spine very extensive MRI examination with high intensity magnet

18.1

6.3

Q79.6

ICD-10 Finland

Ehlers-Danlos syndrome

18.1

6.3

N02CC03

ATC

zolmitriptan; nasal, oral

2.2

6.3

285

I20.81

ICD-10 Finland

Other angina pectoris stenosed coronary artery

2.0

6.3

385

72830

ICD-8 Finland

Vertebrogenic pain syndrome, Radicular syndrome of upper limbs

+∞

6.3

G99.2*M51.0

ICD-10 Finland

Lumbar and other intervertebral disc disorders with myelopathy

+∞

6.3

7214A

ICD-9 Finland

Spondylosis and allied disorders, Thoracic or lumbar spondylosis with myelopathy

+∞

6.3

72898

ICD-8 Finland

Vertebrogenic pain syndrome, Alia definita

+∞

6.3

7225B

ICD-9 Finland

Intervertebral disk disorders, Degeneration of thoracic or lumbar intervertebral disk[DEGEN DISCI INTERVERT THORAC SEU LUMBOSACR CUM INST]

+∞

6.3

NAG65

NOMESCO Finland

Anterior and posterior fusion of lumbar spine

+∞

6.3

71700

ICD-8 Finland

+∞

6.3

9183

FHL

Posterolateral spondylodesis

+∞

6.3

G99.2

ICD-10 Finland

Myelopathy in diseases classified elsewhere

+∞

6.3

RF223

NOMESCO Finland

+∞

6.3

M46.4

ICD-10 Finland

Discitis, unspecified

+∞

6.3

SPAT1203

SPAT

Injection therapy, other than intramuscular or subcutaneous

2.5

6.2

183

M99.3

ICD-10 Finland

Osseous stenosis of neural canal

26.8

6.2

SPAT1059

SPAT

Spirometry at the office

2.2

6.2

275

M80.9

ICD-10 Finland

Unspecified osteoporosis with pathological fracture

4.1

6.2

SPAT1028

SPAT

Ultrasound examination of paranasal sinuses

2.2

6.2

300

J01FA01

ATC

erythromycin; systemic

1.6

6.2

146

935

NBL22

NOMESCO Finland

Myotomy, tenotomy or excision of tendon of upper arm

4.5

6.2

A46

ICD-10 Finland

Erysipelas

1.7

6.2

133

830

D19

ICPC

Teeth/gum symptom/complaint

1.4

6.1

270

1992

XQ800

NOMESCO Finland

Prick test

2.0

6.1

409

K07.63

ICD-10 Finland

Pain in the jaw joint UNS

4.3

6.1

M01AE11

ATC

tiaprofenic acid; oral, rectal

2.5

6.1

186

SPAT1292

SPAT

Other function in accordance with SHToL (Finnish classification of nursing interventions)

1.9

6.1

500

79199

ICD-8 Finland

Headache

4.7

6.1

F34.1

ICD-10 Finland

Dysthymia

2.6

6.1

161

S03CA04

ATC

hydrocortisone and antiinfectives; ophthalmic, otic (ophth. and otological prep., corticosteroids and antiinfectives in comb.)

2.6

6.1

154

SPAT1144

SPAT

Treatment of reopened or infected surgical wound

2.0

6.1

383

WX105

NOMESCO Finland

Surface analgesia on skin or mucosa

1.8

6.1

536

M10.9

ICD-10 Finland

Gout, unspecified

2.2

6.1

271

SHA03

NOMESCO Finland

Correction of physiology of bite - demanding therapy visit

2.9

6.1

124

SBB10

NOMESCO Finland

Teeth copy

2.2

6.1

272

R03AC12

ATC

salmeterol; inhalant

2.2

6.0

252

SPAT1215

SPAT

Assessment of need for medical rehabilitation

2.5

6.0

181

NAME	M13_DORSOPATHYNAS
CONTROL_EXCLUDE	M13_DORSOPATHY
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M53[8-9]
HD_ICD_9	724[8-9]
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	M53[8-9]
COD_ICD_9	724[8-9]
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Parameter	HR [95% CI]	p-value
M13_DORSOPATHYNAS	1.224 [1.09, 1.38]	< 0.001
Birth year	0.994 [0.99, 1.0]	0.154

Parameter	HR [95% CI]	p-value
M13_DORSOPATHYNAS	1.185 [1.03, 1.37]	0.021
Birth year	0.988 [0.98, 1.0]	0.012

N-year risk	Females	Males
1	0.1%	0.25%
5	0.652%	1.216%
10	1.647%	3.198%
15	3.158%	6.424%
20	5.584%	10.908%

Other specified/unspecified dorsopathies

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints