No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleonly females |
293373 |
2. Check conditionsNone |
293373 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
2395 |
4. Check minimum number of eventsNone |
2395 |
5. Include endpointsNone |
2395 |
6. Filter based on genotype QC (FinnGen only) |
2395 |
Control definitions (FinnGen only)
- Control exclude
- O15_COMPLIC_LAB_DELIV
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF3
- Parent code in ICD-10
- O60-O75
- Name in latin
- Tentamen inductionis laborum
Similar endpoints
↥List of similar endpoints to
Failed induction of labour
based on the number of shared cases.
Similar with more cases:
- Complications of labour and delivery
- Pregnancy, childbirth and the puerperium
- Any event in hilmo or specialist outpatient
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 14576 | 14576 | - |
| Only index persons | 14427 | 14427 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.42 | 0.42 | - |
| Only index persons | 0.53 | 0.53 | - |
| Median age at first event (years) | |||
| Whole population | - | 31.09 | - |
| Only index persons | - | 31.06 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 2395 | 2395 | - |
| Unadjusted period prevalence (%) | 0.82 | 0.82 | - |
| Median age at first event (years) | 31.44 | 31.44 | - |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 2090
- Matched controls
- 20900
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
O34.2
ICD-10 Finland
Maternal care due to uterine scar from previous surgery
22.4
323.0
726
485
MCA10
NOMESCO Finland
Lower uterine segment caesarean section
30.0
323.0
1331
1155
O82.10
ICD-10 Finland
Delivery by emergency caesarean section
52.3
323.0
954
330
O61.0
ICD-10 Finland
Failed medical induction of labour
+∞
323.0
1348
*
O61.1
ICD-10 Finland
Failed instrumental induction of labour
+∞
322.5
301
*
O61.8
ICD-10 Finland
Other failed induction of labour
+∞
314.7
294
*
O68.0
ICD-10 Finland
Labour and delivery complicated by fetal heart rate anomaly
+∞
304.8
285
*
MA2AE
NOMESCO Finland
Ultrasound examination of pregnancy (at 12. week of gestaion or later) including basic examination of fetus
5.6
283.9
1214
4157
Z36.3
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
4.7
235.1
1442
6700
Z39.2
ICD-10 Finland
Routine postpartum follow-up
4.7
219.6
1022
3522
WX320
NOMESCO Finland
Spinalanesthesy
5.9
207.9
693
1631
SPAT1197
SPAT
Extensive health check-up of expecting family
4.4
204.0
1030
3768
O24.4
ICD-10 Finland
Diabetes mellitus arising in pregnancy
5.4
200.9
727
1873
O63.0
ICD-10 Finland
Prolonged first stage (of labour)
+∞
199.2
188
*
W78
ICPC
Pregnancy
4.1
191.7
1120
4611
SPAT1379
SPAT
Health check-up of pregnant person
4.3
188.0
932
3280
O36.6
ICD-10 Finland
Maternal care for excessive fetal growth
9.1
185.5
421
562
O72.1
ICD-10 Finland
Other immediate postpartum haemorrhage
1962.3
179.8
172
*
MAC10
NOMESCO Finland
Antepartum dilatation of cervical canal
11.4
176.4
349
360
WX306
NOMESCO Finland
Lumbar epidural anesthesy
6.2
174.6
531
1083
SPAT1380
SPAT
Postpartum check-up
4.3
173.6
816
2685
ZXD05
NOMESCO Finland
Urgent procedure
3.9
171.1
992
3932
MAC40
NOMESCO Finland
Pharmacological induction or advancement of labor
14.7
167.4
292
228
MA2HE
NOMESCO Finland
Detailed morfological ultrasound examination of fetus
3.6
156.4
1012
4301
W92
ICPC
Compl labour/ delivery livebirth
14.2
148.7
263
210
O75.6
ICD-10 Finland
Delayed delivery after spontaneous or unspecified rupture of membranes
+∞
135.9
129
*
6591A
ICD-9 Finland
Other indications for care or intervention related to labour and delivery and not elsewhere classified, Failed medical or unspecified induction
+∞
134.9
128
*
O48
ICD-10 Finland
Prolonged pregnancy
7.3
132.5
344
549
O64.0
ICD-10 Finland
Obstructed labour due to incomplete rotation of fetal head
+∞
122.1
116
*
O82.0
ICD-10 Finland
Delivery by elective caesarean section
5.9
120.1
368
728
W85
ICPC
Gestational diabetes
5.5
115.8
379
809
O70.1
ICD-10 Finland
Second degree perineal laceration during delivery
402.3
115.7
115
*
MA2DE
NOMESCO Finland
Detailed ultrasound examination of fetus including color doppler method
3.7
114.6
606
2070
O13
ICD-10 Finland
Gestational [pregnancy-induced] hypertension
5.3
113.6
388
869
O99.80
ICD-10 Finland
The fear of childbirth
5.2
110.9
381
857
O81.4
ICD-10 Finland
Vacuum extractor delivery
15.9
107.2
179
122
SPAT1317
SPAT
Planned health check-up monitoring, health check-up performed based on individual need
3.4
106.1
639
2396
Z35.8
ICD-10 Finland
Supervision of other high-risk pregnancies
3.6
104.6
572
1987
O41.1
ICD-10 Finland
Infection of amniotic sac and membranes
29.6
103.6
141
51
O63.1
ICD-10 Finland
Prolonged second stage (of labour)
+∞
103.0
98
*
Z34.0
ICD-10 Finland
Supervision of normal first pregnancy
3.0
102.7
801
3591
O72.0
ICD-10 Finland
Third-stage haemorrhage
+∞
101.9
97
*
WX600
NOMESCO Finland
Single shot through catheter
13.1
97.7
177
146
MA2JE
NOMESCO Finland
Ultrasound screening of fetal nuchal translucency
3.3
95.3
592
2244
B01AB05
ATC
enoxaparin; parenteral
3.2
91.7
601
2357
O61.9
ICD-10 Finland
Failed induction of labour, unspecified
+∞
90.3
86
*
O80.8
ICD-10 Finland
Other single spontaneous delivery
4.2
82.9
347
937
MAE00
NOMESCO Finland
Outlet vacuum delivery
13.1
79.8
144
117
Z34.8
ICD-10 Finland
Supervision of other normal pregnancy
2.6
79.4
796
4010
W84
ICPC
Pregnancy high risk
4.6
78.0
298
733
WX602
NOMESCO Finland
Repeated or continuing anesthesia shots throug a catheter
3.3
76.7
449
1595
O60
ICD-10 Finland
Preterm labour and delivery
743.7
73.6
72
*
MAC96
NOMESCO Finland
Other induction or advancement of labour
5.6
70.6
221
435
Z32.1
ICD-10 Finland
Pregnancy confirmed
2.6
68.8
608
2803
SPAT1399
SPAT
Acceptance of acknowledgement of paternity of child born outside of marriage before the birth of the child at the maternity clinic. Paternity Act, Section 16.
3.8
65.3
307
907
O72.2
ICD-10 Finland
Delayed and secondary postpartum haemorrhage
91.9
64.3
71
8
E66.01
ICD-10 Finland
Obesity due to excess calories
3.3
62.1
356
1228
MAW96
NOMESCO Finland
Other operation in pregnancy or at delivery
20.8
58.7
88
44
MAC01
NOMESCO Finland
Rupture of aminiotic membrane for induction of labor
6.0
57.5
166
294
O26.82
ICD-10 Finland
Exhaustion and fatigue pregnancy-related
5.5
55.6
173
336
SPAT1373
SPAT
Combined screening in early pregnancy
5.3
52.8
169
339
O64.1
ICD-10 Finland
Obstructed labour due to breech presentation
+∞
52.3
50
*
A10BA02
ATC
metformin; oral
2.9
51.0
351
1359
SPAT1195
SPAT
Antenatal classes
3.8
50.6
232
665
Z36.0
ICD-10 Finland
Antenatal screening for chromosomal anomalies
3.1
50.5
307
1092
8811
FHL
Cesarean section
7.7
50.3
121
166
O24.0
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, insulin-dependent
6.3
49.9
139
235
MA1AE
NOMESCO Finland
Ultrasound examination of early pregnancy (before 12. postmenstrual week)
2.3
49.4
575
2972
O14.9
ICD-10 Finland
Pre-eclampsia, unspecified
7.2
48.8
123
181
MA3AE
NOMESCO Finland
Combined first trimester screening
3.2
48.6
287
999
Z39.1
ICD-10 Finland
Care and examination of lactating mother
5.3
48.1
154
309
Z35.2
ICD-10 Finland
Supervision of pregnancy with other poor reproductive or obstetric history
6.0
48.0
139
247
O47.0
ICD-10 Finland
False labour before 37 completed weeks of gestation
2.5
47.3
449
2088
O62.0
ICD-10 Finland
Primary inadequate contractions
+∞
47.0
45
*
MA5AE
NOMESCO Finland
Morphology ultrasound screening, weeks 18+0 to 21+6 of gestation
3.1
46.4
285
1016
O36.8
ICD-10 Finland
Maternal care for other specified fetal problems
5.5
46.2
142
271
SPAT1200
SPAT
Guidance for breast-feeding and breast care
3.8
44.8
205
584
O99.2
ICD-10 Finland
Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
5.2
43.6
141
286
O32.1
ICD-10 Finland
Maternal care for breech presentation
3.2
39.9
230
783
O40
ICD-10 Finland
Polyhydramnios
7.7
39.5
94
127
N02BE01
ATC
paracetamol; systemic, rectal
2.1
39.4
1733
14572
O99.89
ICD-10 Finland
Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
4.4
38.7
147
353
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
3.5
38.4
191
581
SPAT1262
SPAT
Handing over of treatment supplies
2.8
38.3
276
1087
Z37.0
ICD-10 Finland
Single live birth
2.2
37.6
471
2473
O10.0
ICD-10 Finland
Pre-existing essential hypertension complicating pregnancy, childbirth and the puerperium
5.4
36.1
112
216
O26.88
ICD-10 Finland
Other specified pregnancy-related conditions
5.0
36.1
120
251
Z35.0
ICD-10 Finland
Supervision of pregnancy with history of infertility
3.7
35.5
164
470
O70.0
ICD-10 Finland
First degree perineal laceration during delivery
342.6
34.0
34
*
MBA30
NOMESCO Finland
Manual removal of placenta from delivered uterus
20.5
33.6
50
25
O68.2
ICD-10 Finland
Labour and delivery complicated by fetal heart rate anomaly with meconium in amniotic fluid
+∞
33.4
32
*
W29
ICPC
Pregnancy symptom/complaint other
3.3
32.3
173
557
O75.3
ICD-10 Finland
Other infection during labour
+∞
31.3
30
*
MBC30
NOMESCO Finland
Repair of partial rupture of perineum
8.0
31.0
71
91
O24.9
ICD-10 Finland
Diabetes mellitus in pregnancy, unspecified
4.3
30.3
118
290
SPAT1249
SPAT
Treatment-related counselling outside office
1.7
30.1
926
6601
SPAT1375
SPAT
Structural ultrasound screening, weeks 18+0-21+6
5.0
29.6
98
204
O73.0
ICD-10 Finland
Retained placenta without haemorrhage
+∞
29.2
28
*
O75.0
ICD-10 Finland
Maternal distress during labour and delivery
+∞
29.2
28
*
O62.1
ICD-10 Finland
Secondary uterine inertia
+∞
29.2
28
*
O24.1
ICD-10 Finland
Diabetes mellitus in pregnancy: Pre-existing diabetes mellitus, non-insulin-dependent
9.9
29.2
59
61
O26.6
ICD-10 Finland
Liver disorders in pregnancy, childbirth and the puerperium
4.4
29.1
110
263
MAA00
NOMESCO Finland
Amniocentesis
3.9
28.9
122
323
WX322
NOMESCO Finland
Combined spinal-epidural analgesia in obstetrics
4.0
28.6
119
311
O68.1
ICD-10 Finland
Labour and delivery complicated by meconium in amniotic fluid
+∞
28.2
27
*
O41.0
ICD-10 Finland
Oligohydramnios
3.8
28.0
123
337
MA2XE
NOMESCO Finland
Other obstetric ultrasound examination
2.2
27.8
316
1565
SPAT1189
SPAT
Other ultrasound examination during pregnancy
2.7
27.7
198
771
O14.0
ICD-10 Finland
Mild to moderate pre-eclampsia
4.2
27.4
107
264
O73.1
ICD-10 Finland
Retained portions of placenta and membranes, without haemorrhage
+∞
27.1
26
*
O68.8
ICD-10 Finland
Labour and delivery complicated by other evidence of fetal stress
+∞
27.1
26
*
O64.8
ICD-10 Finland
Obstructed labour due to other malposition and malpresentation
+∞
27.1
26
*
6610B
ICD-9 Finland
Abnormality of forces of labour, Primary uterine inertia
+∞
27.1
26
*
O42.9
ICD-10 Finland
Premature rupture of membranes, unspecified
2.9
26.9
169
606
SPAT1246
SPAT
Screening of depression or other psychiatric problem
2.6
26.7
211
869
SPAT1196
SPAT
Monitoring of normal pregnancy
2.1
26.3
356
1898
O86.0
ICD-10 Finland
Infection of obstetric surgical wound
7.8
26.3
61
80
OAA12
SPAT
NA
4.3
26.2
101
246
Z34.9
ICD-10 Finland
Supervision of normal pregnancy, unspecified
1.9
26.0
488
2944
O42.1
ICD-10 Finland
Premature rupture of membranes, onset of labour after 24 hours
5.3
25.8
80
155
R3110
NOMESCO Finland
Psychosocial training
4.6
25.4
90
202
O99.3
ICD-10 Finland
Mental disorders and diseases of the nervous system complicating pregnancy, childbirth and the puerperium
3.6
25.3
119
346
SPAT1306
SPAT
Counselling and guidance related to nutrition and weight management
2.1
24.6
296
1498
WX307
NOMESCO Finland
Obstetric epidural analgesia
1.9
24.3
382
2156
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.6
23.6
941
7045
O36.5
ICD-10 Finland
Maternal care for poor fetal growth
2.9
23.5
149
535
Z35.9
ICD-10 Finland
Supervision of high-risk pregnancy, unspecified
2.8
23.1
160
610
OAA11
SPAT
NA
2.8
23.0
159
606
O82.11
ICD-10 Finland
Childbirth with an emergency caesarean section in an emergency
15.0
22.5
37
25
E66.9
ICD-10 Finland
Obesity, unspecified
3.2
22.0
118
380
SPAT1263
SPAT
Sampling
1.6
22.0
921
6941
O68.3
ICD-10 Finland
Labour and delivery complicated by biochemical evidence of fetal stress
+∞
21.9
21
*
O75.2
ICD-10 Finland
Pyrexia during labour, not elsewhere classified
+∞
21.9
21
*
O35.8
ICD-10 Finland
Maternal care for other (suspected) fetal abnormality and damage
3.3
21.6
111
346
O65.4
ICD-10 Finland
Obstructed labour due to fetopelvic disproportion, unspecified
222.2
21.6
22
*
WYA40
NOMESCO Finland
Assessment of oral health and treatment needs for family expecting first child
3.4
21.5
108
331
O32.2
ICD-10 Finland
Maternal care for transverse and oblique lie
7.6
20.9
49
66
6590A
ICD-9 Finland
Other indications for care or intervention related to labour and delivery and not elsewhere classified, Failed mechanical induction
+∞
20.9
20
*
O14.1
ICD-10 Finland
Severe pre-eclampsia
6.2
20.8
56
92
Z10.8
ICD-10 Finland
Routine general health check-up of other defined subpopulations
2.7
20.5
141
536
SPAT1357
SPAT
Monitoring of problem during pregnancy
2.7
20.3
147
575
O02.1
ICD-10 Finland
Missed abortion
2.1
20.2
236
1176
SPAT1153
SPAT
Removal of sutures
1.8
20.0
439
2756
O47.9
ICD-10 Finland
False labour, unspecified
3.5
20.0
95
280
Z34
ICD-10 Finland
Supervision of normal pregnancy
2.2
19.6
220
1077
MWA00
NOMESCO Finland
Repair of wound dehiscence in obstetric surgery
24.8
19.5
27
11
A02BC01
ATC
omeprazole; systemic
1.7
19.2
437
2769
Z36.4
ICD-10 Finland
Antenatal screening for fetal growth retardation using ultrasound and other physical methods
4.0
19.1
77
197
O80.0
ICD-10 Finland
Spontaneous vertex delivery
0.6
19.1
656
8679
Z30.2
ICD-10 Finland
Sterilization
2.0
19.0
271
1463
MBA04
NOMESCO Finland
Curettage of uterus after delivery
34.7
18.9
24
7
O41.8
ICD-10 Finland
Other specified disorders of amniotic fluid and membranes
10.2
18.9
37
37
O66.2
ICD-10 Finland
Obstructed labour due to unusually large fetus
+∞
18.8
18
*
6622B
ICD-9 Finland
Long labour, Prolonged second stage
+∞
18.8
18
*
O21.9
ICD-10 Finland
Vomiting of pregnancy, unspecified
3.5
18.6
87
253
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.7
18.6
129
492
LA2AE
NOMESCO Finland
Ultrasound examination of ovarian cyst
2.7
18.5
129
493
SPAT1236
SPAT
Informing family of child’s disability
5.7
18.2
52
93
O30.0
ICD-10 Finland
Twin pregnancy
4.0
18.1
74
192
215
Kela drug reimbursment
Diabetes, non-insulin-treated
2.0
17.9
229
1184
6441A
ICD-9 Finland
Early or threatened labour, Other threatened labour
+∞
17.7
17
*
O71.4
ICD-10 Finland
Obstetric high vaginal laceration
+∞
17.7
17
*
103
Kela drug reimbursment
Diabetes, insulin-treated
2.0
17.7
230
1196
Z35
ICD-10 Finland
Supervision of high-risk pregnancy
4.3
17.2
64
153
G03GA01
ATC
chorionic gonadotrophin; parenteral
2.2
17.0
179
850
O20.9
ICD-10 Finland
Haemorrhage in early pregnancy, unspecified
2.5
16.8
136
567
O75.5
ICD-10 Finland
Delayed delivery after artificial rupture of membranes
+∞
16.7
16
*
O75.7
ICD-10 Finland
Vaginal delivery following previous caesarean section
+∞
16.7
16
*
O62.2
ICD-10 Finland
Other uterine inertia
90.8
16.6
18
*
TMW99
NOMESCO Finland
Other minor surgical procedure in obstetrics
5.3
16.5
50
96
O99.1
ICD-10 Finland
Other diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism complicating pregnancy, childbirth and the puerperium
5.0
16.5
53
109
LGA20
NOMESCO Finland
Sterilisation by constriction of Fallopian tubes
5.3
16.4
50
97
N97.9
ICD-10 Finland
Female infertility, unspecified
1.9
16.4
260
1459
O12.0
ICD-10 Finland
Gestational oedema
7.2
16.3
39
55
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.1
16.1
189
944
B01AB04
ATC
dalteparin; parenteral
3.6
15.9
72
205
O35.9
ICD-10 Finland
Maternal care for (suspected) fetal abnormality and damage, unspecified
4.3
15.9
59
141
O65.5
ICD-10 Finland
Obstructed labour due to abnormality of maternal pelvic organs
+∞
15.6
15
*
P01AB01
ATC
metronidazole; oral, rectal
1.5
14.9
808
6275
J01DB01
ATC
cefalexin; oral
1.6
14.8
1675
15091
MAB10
NOMESCO Finland
External version
4.8
14.7
48
101
E66.8
ICD-10 Finland
Other obesity
2.2
14.7
154
731
OAB30
SPAT
NA
5.6
14.7
42
76
O66.0
ICD-10 Finland
Obstructed labour due to shoulder dystocia
+∞
14.6
14
*
O70.2
ICD-10 Finland
Third degree perineal laceration during delivery
+∞
14.6
14
*
A05AA02
ATC
ursodeoxycholic acid; oral
3.7
14.6
63
173
Z32.0
ICD-10 Finland
Pregnancy, not (yet) confirmed
2.4
14.5
124
533
A10AE05
ATC
insulin detemir; parenteral
2.7
14.5
99
377
SPAT1310
SPAT
Counselling related to known health issue
1.5
14.4
612
4504
LGA10
NOMESCO Finland
Sterilisation by destruction or division of Fallopian tubes
6.6
14.3
36
55
MBA03
NOMESCO Finland
Curettage of uterus after delivery or abortion
2.8
14.3
93
343
Z35.4
ICD-10 Finland
Supervision of pregnancy with grand multiparity
5.5
13.8
40
74
ZXE00
NOMESCO Finland
One hour or less
1.5
13.7
731
5628
6522B
ICD-9 Finland
Malposition and malpresentation of foetus, Breech presentation without mention of version[PRAESENTATIO CLUNIUM,SYNNYTYKSEN AIKANA]
+∞
13.6
13
*
Z3232
NOMESCO Finland
Midwife
1.6
13.5
369
2436
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
1.9
13.3
193
1045
A10AB04
ATC
insulin lispro; parenteral (insulins and analog. for injection, fast-acting)
2.7
12.8
89
344
XMA22
NOMESCO Finland
General examination of pregnant woman
1.8
12.8
232
1361
Z87.5
ICD-10 Finland
Personal history of complications of pregnancy, childbirth and the puerperium
4.6
12.7
43
95
K80.2
ICD-10 Finland
Calculus of gallbladder without cholecystitis
1.9
12.5
194
1075
MAC00
NOMESCO Finland
Rupture of amniotic membrane
8.3
12.5
27
33
O67.9
ICD-10 Finland
Intrapartum haemorrhage, unspecified
+∞
12.5
12
*
6620B
ICD-9 Finland
Long labour, Prolonged first stage
+∞
12.5
12
*
W05
ICPC
Pregnancy vomiting/nausea
3.6
12.5
55
155
TLW00
NOMESCO Finland
Insemination
2.5
12.3
98
405
W18
ICPC
Post-partum symptom/complaint other
5.2
12.3
37
72
O84.2
ICD-10 Finland
Multiple delivery, all by caesarean section
8.5
12.3
26
31
O21
ICD-10 Finland
Excessive vomiting in pregnancy
3.9
12.2
49
127
WW500
NOMESCO Finland
Blood transfusion
3.8
12.2
51
137
O90.2
ICD-10 Finland
Haematoma of obstetric wound
37.8
12.2
15
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
12.2
786
6246
Z12.4
ICD-10 Finland
Special screening examination for neoplasm of cervix
2.5
12.1
91
368
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
2.1
12.0
142
711
O33.5
ICD-10 Finland
Maternal care for disproportion due to unusually large fetus
7.3
12.0
28
39
L02BG04
ATC
letrozole; oral
2.1
12.0
137
675
CL2S4
NOMESCO Finland
Ocular fundus photography for diabetic retinopathy screening
4.4
11.9
42
97
O28.0
ICD-10 Finland
Abnormal haematological finding on antenatal screening of mother
11.8
11.8
21
18
O32.0
ICD-10 Finland
Maternal care for unstable lie
6.2
11.8
31
51
H01CA02
ATC
nafarelin; nasal
2.3
11.8
109
489
Z39.0
ICD-10 Finland
Care and examination immediately after delivery
3.3
11.6
57
175
A10AE04
ATC
insulin glargine; parenteral
2.2
11.6
116
540
Z36.8
ICD-10 Finland
Other antenatal screening
2.6
11.6
84
332
MAA40
NOMESCO Finland
Puncture of fetus
6.2
11.5
30
49
O26.7
ICD-10 Finland
Subluxation of symphysis (pubis) in pregnancy, childbirth and the puerperium
3.2
11.5
58
182
G03GA06
ATC
follitropin beta; parenteral
2.4
11.5
99
429
SPAT1391
SPAT
Counselling and guidance related to family situation
3.0
11.1
64
220
LX1AE
NOMESCO Finland
Gynecological ultrasound examination as part of clinical examination
1.5
11.0
358
2460
M54.5
ICD-10 Finland
Low back pain
1.4
10.9
642
4988
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.4
10.9
634
4917
Z35.5
ICD-10 Finland
Supervision of elderly primigravida
6.0
10.9
29
49
E66.00
ICD-10 Finland
Metabolic syndrome
2.6
10.7
79
316
OAA10
SPAT
NA
2.6
10.7
76
298
MCA00
NOMESCO Finland
Upper uterine segment caesarean section
21.6
10.7
15
7
E10.9
ICD-10 Finland
Type 1 diabetes mellitus, Without complications
2.2
10.7
104
477
G03GA05
ATC
follitropin alfa; parenteral
2.0
10.6
130
663
Z39
ICD-10 Finland
Postpartum care and examination
3.1
10.5
56
184
O66.5
ICD-10 Finland
Failed application of vacuum extractor and forceps, unspecified
+∞
10.4
10
*
6611B
ICD-9 Finland
Abnormality of forces of labour, Secondary uterine inertia
+∞
10.4
10
*
O03.9
ICD-10 Finland
Spontaneous abortion, Complete or unspecified, without complication
1.8
10.3
169
957
O90.0
ICD-10 Finland
Disruption of caesarean section wound
16.1
10.3
16
10
J01CA08
ATC
pivmecillinam; oral
1.4
10.2
1020
8641
O20.0
ICD-10 Finland
Threatened abortion
2.3
9.9
92
416
NE1AG
NOMESCO Finland
MRI pelvimetry with high intensity magnet
4.2
9.9
36
87
H01CC01
ATC
ganirelix; parenteral
2.1
9.7
112
555
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.4
9.7
557
4289
O36.0
ICD-10 Finland
Maternal care for rhesus isoimmunization
13.4
9.7
16
12
LAA10
NOMESCO Finland
Percutaneous or transvaginal puncture and recovery of oocyte
2.1
9.6
111
550
E66
ICD-10 Finland
Obesity
2.1
9.6
111
551
Z71.9
ICD-10 Finland
Counselling, unspecified
2.0
9.5
120
619
W03
ICPC
Antepartum bleeding
3.4
9.5
44
131
ZXE10
NOMESCO Finland
More than one and less than three hours
1.4
9.4
521
3983
6522A
ICD-9 Finland
Malposition and malpresentation of foetus, Breech presentation without mention of version[PRAESENTATIO CLUNIUM,RASKAUDEN AIKANA]
+∞
9.4
9
*
W90
ICPC
Uncompl labour/delivery livebirth
1.7
9.4
206
1277
8801
FHL
Suction cup delivery
5.3
9.4
27
51
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.7
9.3
198
1217
MWE00
NOMESCO Finland
Reoperation for deep haemorrhage in obstetric surgery
21.8
9.3
13
6
O28.1
ICD-10 Finland
Abnormal biochemical finding on antenatal screening of mother
4.5
9.3
31
69
SPAT1381
SPAT
Extensive health check-up at 4 months of age
4.0
9.2
35
88
W19
ICPC
Lactation symptom/complaint
4.4
9.2
32
74
MBA00
NOMESCO Finland
Vacuum aspiration from uterus after delivery or abortion
2.4
9.2
75
317
G56.0
ICD-10 Finland
Carpal tunnel syndrome
1.7
9.1
205
1278
S18
ICPC
Laceration/cut
1.4
9.1
524
4033
MAE03
NOMESCO Finland
Mid-cavity or high vacuum delivery
36.8
9.0
11
*
TLW12
NOMESCO Finland
Insertion of frozen embryo
2.3
8.8
76
331
OAA70
SPAT
NA
3.6
8.7
38
108
SPAT1240
SPAT
Therapeutic discussion
1.5
8.7
318
2237
O28.8
ICD-10 Finland
Other abnormal findings on antenatal screening of mother
2.7
8.7
56
209
G03DA04
ATC
progesterone; systemic, rectal, vaginal
2.3
8.7
75
326
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.8
8.7
136
758
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.7
8.7
199
1248
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.4
8.6
601
4769
O02.0
ICD-10 Finland
Blighted ovum and nonhydatidiform mole
2.0
8.6
112
586
H04AA01
ATC
glucagon; nasal, parenteral
2.4
8.5
71
306
J03.9
ICD-10 Finland
Acute tonsillitis, unspecified
1.7
8.5
176
1073
Z31.1
ICD-10 Finland
Artificial insemination
4.2
8.4
30
72
O28.3
ICD-10 Finland
Abnormal ultrasonic finding on antenatal screening of mother
3.6
8.3
36
102
K42.9
ICD-10 Finland
Umbilical hernia without obstruction or gangrene
2.6
8.3
58
227
6534B
ICD-9 Finland
Disproportion, Foetopelvic disproportion[DISPROPORTIO FOETOPELVICA,SYNNYTYKSEN AIKANA]
+∞
8.3
8
*
O66.4
ICD-10 Finland
Failed trial of labour, unspecified
+∞
8.3
8
*
O69.1
ICD-10 Finland
Labour and delivery complicated by cord around neck, with compression
+∞
8.3
8
*
Z46.9
ICD-10 Finland
Fitting and adjustment of unspecified device
8.6
8.3
17
20
SPAT1315
SPAT
Periodic health check-up of children and adolescents
1.8
8.3
144
833
E10.3
ICD-10 Finland
Type 1 diabetes mellitus, With ophthalmic complications
2.3
8.3
76
344
O03.1
ICD-10 Finland
Spontaneous abortion, Incomplete, complicated by delayed or excessive haemorrhage
2.5
8.2
63
258
O03.4
ICD-10 Finland
Spontaneous abortion, Incomplete, without complication
2.1
8.2
88
427
O26.9
ICD-10 Finland
Pregnancy-related condition, unspecified
4.2
8.1
29
70
T90
ICPC
Diabetes non-insulin dependent
1.8
8.1
146
857
O46.9
ICD-10 Finland
Antepartum haemorrhage, unspecified
2.4
8.0
65
274
SPAT1128
SPAT
Instruction of pelvic floor / sphincter exercises
3.2
8.0
40
127
LGA00
NOMESCO Finland
Sterilisation by ligature of Fallopian tubes
6.3
8.0
20
32
SPAT1312
SPAT
General health counselling
1.3
8.0
648
5254
C07AG01
ATC
labetalol; systemic
3.2
8.0
39
122
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
1.7
8.0
155
926
SPAT1303
SPAT
Counselling and guidance related to growth and development
3.1
8.0
42
139
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.4
8.0
422
3190
O44.0
ICD-10 Finland
Placenta praevia specified as without haemorrhage
3.3
7.9
38
118
Z48.0
ICD-10 Finland
Attention to surgical dressings and sutures
2.9
7.9
46
162
FM1QE
NOMESCO Finland
Extensive ultrasound of fetal heart
3.2
7.8
39
124
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.4
7.8
440
3358
B01AB10
ATC
tinzaparin; parenteral
2.1
7.8
84
407
Z30.1
ICD-10 Finland
Insertion of (intrauterine) contraceptive device
1.4
7.7
500
3909
LC2HE
NOMESCO Finland
Hystero-salpingography with ultrasound
1.7
7.7
166
1026
T89
ICPC
Diabetes insulin dependent
2.2
7.7
77
363
O85
ICD-10 Finland
Puerperal sepsis
3.3
7.7
37
115
O36.4
ICD-10 Finland
Maternal care for intrauterine death
4.1
7.7
28
69
WZC30
SPAT
NA
3.6
7.7
32
89
Z31.2
ICD-10 Finland
In vitrofertilization
3.1
7.6
39
127
O99.0
ICD-10 Finland
Anaemia complicating pregnancy, childbirth and the puerperium
2.9
7.5
43
149
E10.8
ICD-10 Finland
Type 1 diabetes mellitus, With unspecified complications
3.6
7.5
32
91
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.0
7.5
95
493
O66.9
ICD-10 Finland
Obstructed labour, unspecified
80.4
7.4
8
*
O36.9
ICD-10 Finland
Maternal care for fetal problem, unspecified
2.9
7.4
41
141
A10AB01
ATC
insulin (human); parenteral (insulins and analog. for injection, fast-acting)
2.1
7.3
75
358
OAA41
SPAT
NA
2.9
7.3
42
145
J01DA01
ATC
[U] cefalexin; systemic
1.3
7.3
1170
10388
6535B
ICD-9 Finland
Disproportion, Unusually large foetus causing disproportion[EPÄTAVALLISEN ISO SIKIÖ (YLI 4500 G), SYNN AIKANA]
+∞
7.3
7
*
O67.8
ICD-10 Finland
Other intrapartum haemorrhage
+∞
7.3
7
*
O71.1
ICD-10 Finland
Rupture of uterus during labour
+∞
7.3
7
*
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.3
7.3
1080
9495
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
7.3
258
1803
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
1.7
7.2
136
808
O16
ICD-10 Finland
Unspecified maternal hypertension
4.6
7.2
23
50
SPAT1389
SPAT
Visit based on need for special support
2.0
7.2
89
458
O99.4
ICD-10 Finland
Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium
3.6
7.2
30
84
N97.0
ICD-10 Finland
Female infertility associated with anovulation
2.0
7.2
91
474
TLC02
NOMESCO Finland
Simple extraction of IUD
1.7
7.2
139
834
8832
FHL
Manual placenta removal and associated scraping
30.1
7.1
9
*
C09AA02
ATC
enalapril; systemic
1.8
7.1
109
607
MBB10
NOMESCO Finland
Packing of delivered uterus
20.1
7.1
10
5
SPAT1283
SPAT
Restricted health certificate
1.3
7.1
626
5124
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.3
7.0
1022
8945
O86.8
ICD-10 Finland
Other specified puerperal infections
5.2
6.9
20
39
MBA05
NOMESCO Finland
Curettage of uterus after abortion
2.5
6.9
49
195
A10AE06
ATC
insulin degludec; parenteral
2.4
6.9
55
233
J01FA10
ATC
azithromycin; systemic
1.3
6.8
1258
11328
O47.1
ICD-10 Finland
False labour at or after 37 completed weeks of gestation
1.7
6.8
132
792
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
6.8
189
1249
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.3
6.8
512
4092
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
2.1
6.7
70
337
R01BA52
ATC
pseudoephedrine, combinations; oral
1.3
6.7
485
3849
W27
ICPC
Fear of complications of pregnancy
2.5
6.7
48
194
O99.6
ICD-10 Finland
Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
2.8
6.7
39
139
SPAT1382
SPAT
Extensive health check-up at 18 months of age
3.2
6.6
32
101
M01AE01
ATC
ibuprofen; systemic, rectal
1.5
6.6
1889
18081
I10
ICD-10 Finland
Essential (primary) hypertension
1.4
6.6
334
2503
O34.1
ICD-10 Finland
Maternal care for tumour of corpus uteri
4.3
6.5
22
51
K35.9
ICD-10 Finland
Acute appendicitis, unspecified
1.6
6.5
169
1101
J01CE02
ATC
phenoxymethylpenicillin; oral
1.3
6.4
1511
13978
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
6.4
371
2842
ZXD00
NOMESCO Finland
Emergency procedure
2.5
6.4
47
193
MBA40
NOMESCO Finland
Pharmacological evacuation of uterus after abortion
2.1
6.3
67
325
R01AD08
ATC
fluticasone; nasal
1.3
6.3
576
4724
O68.9
ICD-10 Finland
Labour and delivery complicated by fetal stress, unspecified
+∞
6.3
6
*
6440B
ICD-9 Finland
Early or threatened labour, Threatened premature labour[PARTUS PRAEMATURUS]
+∞
6.3
6
*
O62.3
ICD-10 Finland
Precipitate labour
+∞
6.3
6
*
6660C
ICD-9 Finland
Postpartum haemorrhage, Third-stage haemorrhage[HAEMORRHAGIA POST PARTUM CUM RETENT PLAC PARTIALI]
+∞
6.3
6
*
6660A
ICD-9 Finland
Postpartum haemorrhage, Third-stage haemorrhage[HAEMORRHAGIA POST PARTUM STADII III]
+∞
6.3
6
*
6671A
ICD-9 Finland
Retained placenta or membranes, without haemorrhage, Retained portions of placenta or membranes, without haemorrhage
+∞
6.3
6
*
MBB96
NOMESCO Finland
Other manual procedure on delivered uterus
+∞
6.3
6
*
O65.3
ICD-10 Finland
Obstructed labour due to pelvic outlet and mid-cavity contraction
+∞
6.3
6
*
O69.0
ICD-10 Finland
Labour and delivery complicated by prolapse of cord
+∞
6.3
6
*
MAE20
NOMESCO Finland
Failed vacuum delivery
26.7
6.2
8
*
R42
ICD-10 Finland
Dizziness and giddiness
1.4
6.2
257
1851
QBJ30
NOMESCO Finland
Correction of abdominal apron
3.3
6.2
29
90
SPAT1149
SPAT
Suture or treatment of traumatic wound
1.7
6.2
123
744
JDF11
NOMESCO Finland
Laparoscopic gastric bypass
2.4
6.1
48
204
SPAT1301
SPAT
No procedures
1.3
6.1
508
4109
G03GA02
ATC
human menopausal gonadotrophin; parenteral
1.9
6.1
84
451
SPAT1281
SPAT
Other administrative function
1.6
6.0
133
827
O24
ICD-10 Finland
Diabetes mellitus in pregnancy
4.1
6.0
21
51
Mortality – FinRegistry
↥Association
Association between endpoint O15_FAILED_INDUCT and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| O15_FAILED_INDUCT | 0.685 [0.51, 0.92] | 0.012 |
| Birth year | 1.001 [0.99, 1.01] | 0.743 |
During the follow-up period (1.1.1998 — 31.12.2019), 54 out of 10535 females with O15_FAILED_INDUCT died.
Males
No dataMortality risk
Mortality risk for people of age
years, who have O15_FAILED_INDUCT.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.077% | No data |
| 5 | 0.481% | No data |
| 10 | 1.265% | No data |
| 15 | 2.423% | No data |
| 20 | 4.321% | No data |
Relationships between endpoints
↥Index endpoint: O15_FAILED_INDUCT – Failed induction of labour
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data