Cerebral aneurysm, nonruptured

I9_ANEURYSM

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 I67.1
  • Hospital discharge: ICD-9 4373
  • Cause of death: ICD-10 I67.1
  • Cause of death: ICD-9 4373

2 out of 7 registries used, show all original rules.

3390

4. Check minimum number of events

None

3390

5. Include endpoints

None

3390

6. Filter based on genotype QC (FinnGen only)

3390

Control definitions (FinnGen only)

Control exclude
I9_CEREBVASC

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
I67
Name in latin
Aneurysma encephali non ruptum

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 17142 10253 6792
Only index persons 15532 9499 6033
Unadjusted period prevalence (%)
Whole population 0.25 0.29 0.19
Only index persons 0.30 0.35 0.23
Median age at first event (years)
Whole population 59.51 60.10 58.55
Only index persons 58.88 59.32 58.18

-FinnGen-

Key figures

All Female Male
Number of individuals 3390 2189 1201
Unadjusted period prevalence (%) 0.67 0.75 0.53
Median age at first event (years) 58.09 57.53 59.10

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
3084
Matched controls
30839
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
151.2
323.0
474
37
I69.3
ICD-10 Finland
Sequelae of cerebral infarction
196.2
323.0
394
23
AA1AD
NOMESCO Finland
CT of head and brain
6.1
323.0
1415
3739
PA2BD
NOMESCO Finland
Extensive CT angiography of brain
77.8
323.0
572
90
PA2BC
NOMESCO Finland
Cerebral extensive angiography with X-ray
813.7
323.0
697
11
PA2CC
NOMESCO Finland
Cerebral very extensive angiography with X-ray
652.7
323.0
496
9
AAC00
NOMESCO Finland
Ligature of intracranial aneurysm
+∞
323.0
1058
*
I67.1
ICD-10 Finland
Cerebral aneurysm, nonruptured
4503599627370496.0
323.0
2963
*
I69.0
ICD-10 Finland
Sequelae of subarachnoid haemorrhage
3238.6
320.2
304
*
I60.9
ICD-10 Finland
Subarachnoid haemorrhage, unspecified
1040.5
294.6
284
*
PA2LT
NOMESCO Finland
Endovascular closure of extensive brain aneurysm
+∞
269.8
255
*
I60.1
ICD-10 Finland
Subarachnoid haemorrhage from middle cerebral artery
+∞
216.2
205
*
I63.3
ICD-10 Finland
Cerebral infarction due to thrombosis of cerebral arteries
1038.9
201.3
195
*
B01AC04
ATC
clopidogrel; oral
4.8
198.1
769
2005
PA2BG
NOMESCO Finland
MRI examination of vessels in the head with high intensity magnet
74.5
183.5
209
30
PA2KT
NOMESCO Finland
Endovascular closure of brain aneurysm
+∞
181.0
172
*
PA2AC
NOMESCO Finland
Cerebral angiography with X-ray
623.5
180.5
177
*
PA3AC
NOMESCO Finland
Carotis angiography with X-ray
358.5
171.0
171
5
PA2YT
NOMESCO Finland
Cerebral artery PTA with stent
+∞
170.4
162
*
AAL00
NOMESCO Finland
Endovascular occlusion of intracranial aneurysm
+∞
170.4
162
*
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
5.8
166.4
520
1044
4373A
ICD-9 Finland
Other and ill-defined cerebrovascular disease, Cerebral aneurysm, nonruptured
+∞
160.8
153
*
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
5.7
156.4
494
1000
R51.80
ICD-10 Finland
Headache
4.0
155.9
738
2266
2161
FHL
Neck ligation, big brain
+∞
134.3
128
*
PA2MT
NOMESCO Finland
Endovascular closure of very extensive brain aneurysm
+∞
132.2
126
*
PA6BD
NOMESCO Finland
Extensive CT of neck arteries
9.2
127.7
279
328
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
3.3
122.1
745
2739
B01AC30
ATC
platelet aggregation inhibitors excl. heparin - combinations
8.2
115.5
272
361
I60.2
ICD-10 Finland
Subarachnoid haemorrhage from anterior communicating artery
+∞
115.3
110
*
AA9CW
NOMESCO Finland
NA
153.3
112.0
118
8
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
380.7
111.1
111
*
I60.0
ICD-10 Finland
Subarachnoid haemorrhage from carotid siphon and bifurcation
+∞
110.0
105
*
K90
ICPC
Stroke/cerebrovascular accident
36.6
108.4
140
40
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
43.7
104.5
130
31
I63.4
ICD-10 Finland
Cerebral infarction due to embolism of cerebral arteries
957.2
95.5
93
*
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
4.7
95.4
350
814
I60.7
ICD-10 Finland
Subarachnoid haemorrhage from intracranial artery, unspecified
+∞
95.3
91
*
AAF00
NOMESCO Finland
Ventriculostomy
67.4
85.0
98
15
4300A
ICD-9 Finland
Subarachnoid haemorrhage[HAEMORRHAGIA SUBARACHNOID. POST ANEURYSMA SACCULARE]
+∞
81.6
78
*
I65.2
ICD-10 Finland
Occlusion and stenosis of carotid artery
100.6
80.3
88
9
PA4AC
NOMESCO Finland
Vertebralis angiography with X-ray
278.1
79.9
81
*
XA800
NOMESCO Finland
Neuropsychological investigation
6.4
79.0
218
361
PA2AD
NOMESCO Finland
CT angiography of brain
37.2
78.7
101
28
N03AB02
ATC
phenytoin; systemic
19.7
77.1
118
62
R42
ICD-10 Finland
Dizziness and giddiness
2.4
77.0
792
3857
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
376.2
74.0
74
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.9
73.5
523
2057
I61.0
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, subcortical
735.4
73.5
72
*
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.5
72.9
378
1189
I10
ICD-10 Finland
Essential (primary) hypertension
2.0
70.3
1893
13753
PA2AG
NOMESCO Finland
Restrected MRI examination of vessels in the head with high intensity magnet
59.4
69.0
81
14
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
2.7
68.9
545
2280
111
Kela drug reimbursment
Epilepsy and comparable convulsive disorders
4.6
67.2
246
565
K91
ICPC
Cerebrovascular disease
28.0
65.6
90
33
G44.2
ICD-10 Finland
Tension-type headache
2.6
65.3
532
2258
AA5BD
NOMESCO Finland
CT of cerebral ischaemia
18.3
64.4
101
57
AA5PD
NOMESCO Finland
CT examination of brain pefusion
52.6
64.3
77
15
I60.3
ICD-10 Finland
Subarachnoid haemorrhage from posterior communicating artery
+∞
62.7
60
*
WX882
NOMESCO Finland
High dependency care
6.6
60.3
161
254
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
5.7
56.8
171
315
N02BE01
ATC
paracetamol; systemic, rectal
2.3
56.2
2702
23340
I67.9
ICD-10 Finland
Cerebrovascular disease, unspecified
90.4
56.1
62
7
205
Kela drug reimbursment
Chronic hypertension
2.0
55.1
926
5473
PA2CG
NOMESCO Finland
Extensive MRI examination of vessels in the head with high intensity magnet
32.5
53.1
70
22
G45.1
ICD-10 Finland
Carotid artery syndrome (hemispheric)
6.0
52.8
151
261
XCK00
NOMESCO Finland
Perimetry
3.3
52.7
291
951
H53.4
ICD-10 Finland
Visual field defects
8.3
52.1
119
149
PAF14
NOMESCO Finland
Thrombendarterectomy of internal carotid artery
179.7
51.0
53
*
I63.0
ICD-10 Finland
Cerebral infarction due to thrombosis of precerebral arteries
506.0
50.6
50
*
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
10.3
50.3
101
101
I60.6
ICD-10 Finland
Subarachnoid haemorrhage from other intracranial arteries
+∞
50.1
48
*
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
50.0
1367
9495
I63.5
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
+∞
48.0
46
*
ZXM40
NOMESCO Finland
Use of fluorescent substance
68.6
47.2
54
8
I63.1
ICD-10 Finland
Cerebral infarction due to embolism of precerebral arteries
+∞
47.0
45
*
PA7BD
NOMESCO Finland
CT angiography of neck and brain
8.7
46.7
103
122
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
46.0
879
5373
I60.4
ICD-10 Finland
Subarachnoid haemorrhage from basilar artery
+∞
45.9
44
*
N03AX14
ATC
levetiracetam; systemic
6.2
45.3
126
210
I63.8
ICD-10 Finland
Other cerebral infarction
84.8
45.0
50
6
C10AA05
ATC
atorvastatin; oral
1.8
43.8
1179
8044
PA7CD
NOMESCO Finland
CT angiography of neck and brain, extensive
14.3
43.2
74
53
Q61.2
ICD-10 Finland
Polycystic kidney, autosomal dominant
15.8
43.2
71
46
PA7AD
NOMESCO Finland
CT angiography of head and neck vasculature
6.1
42.9
120
202
C08CA01
ATC
amlodipine; oral
1.8
42.8
1108
7452
G40.22
ICD-10 Finland
Complex partial epileptic seizure with secondary generalization
6.7
42.2
111
172
XX4AW
NOMESCO Finland
NA
79.6
42.0
47
6
R56.8
ICD-10 Finland
Other and unspecified convulsions
3.9
41.9
179
474
H53.1
ICD-10 Finland
Subjective visual disturbances
3.0
41.9
256
896
G40.29
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
8.1
41.7
96
122
H53.2
ICD-10 Finland
Diplopia
4.9
41.2
141
301
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
3.1
41.2
244
833
N03AF02
ATC
oxcarbazepine; oral
4.7
39.1
137
300
N03AF01
ATC
carbamazepine; oral, rectal
3.3
38.5
208
667
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
3.1
38.1
223
757
TAB00
NOMESCO Finland
Lumbar puncture
3.6
37.6
176
504
H49.0
ICD-10 Finland
Third [oculomotor] nerve palsy
21.5
37.4
55
26
G45.0
ICD-10 Finland
Vertebro-basilar artery syndrome
5.4
37.2
115
219
G91.0
ICD-10 Finland
Communicating hydrocephalus
22.0
37.0
54
25
C07AB07
ATC
bisoprolol; oral
1.6
35.7
1397
10413
I67.0
ICD-10 Finland
Dissection of cerebral arteries, nonruptured
+∞
35.5
34
*
R4150
NOMESCO Finland
Neuropsychological rehabilitation
19.2
34.8
53
28
I72.0
ICD-10 Finland
Aneurysm and dissection of carotid artery
182.0
34.8
36
*
G40.9
ICD-10 Finland
Epilepsy, unspecified
4.4
34.2
127
295
AAF05
NOMESCO Finland
Ventriculoperitoneal shunt
9.6
32.5
67
71
N18
ICPC
Paralysis/weakness
8.2
32.3
73
91
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
5.3
31.8
99
191
R20.2
ICD-10 Finland
Paraesthesia of skin
2.7
31.7
230
893
I61.1
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, cortical
+∞
31.3
30
*
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.9
30.8
503
2849
R51
ICD-10 Finland
Headache
3.0
30.7
186
643
PA6DE
NOMESCO Finland
Neck artery ultrasound examination with Doppler method
3.5
29.8
143
419
43090
ICD-8 Finland
Subarachnoid haemorrhage, Postaneurysma sacculare, hypertonia non indicata
+∞
29.2
28
*
AA1AM
NOMESCO Finland
Short MRI examination of brain with 3 Tesla magnet
22.4
29.1
42
19
182
Kela drug reimbursment
Brivaracetam, eslikarbazepin, gabapentin, lacosamide, levetiracetam, perampanel, pregabalin, tiagabin and zonisamide
5.5
28.7
86
159
C10AA01
ATC
simvastatin; oral
1.5
28.3
1258
9491
Q28.3
ICD-10 Finland
Other malformations of cerebral vessels
20.3
28.2
42
21
C07AB02
ATC
metoprolol; systemic
1.8
27.9
613
3824
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.3
27.8
266
1198
G43.9
ICD-10 Finland
Migraine, unspecified
2.9
27.6
174
618
N03AG01
ATC
valproic acid; systemic, rectal
2.7
27.0
195
754
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
26.7
452
2584
B01AC07
ATC
dipyridamole; systemic
3.9
26.6
114
304
I62.0
ICD-10 Finland
Nontraumatic subdural haemorrhage
+∞
26.1
25
*
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
3.0
26.0
159
554
C08CA06
ATC
nimodipine; systemic
262.7
25.7
26
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.5
25.2
1356
10588
N02AX02
ATC
tramadol; systemic, rectal
1.5
24.8
1230
9418
I63.2
ICD-10 Finland
Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
131.1
24.6
26
*
WX892
NOMESCO Finland
Monitored bed care
2.4
24.0
220
968
B01AA03
ATC
warfarin; systemic
1.8
23.7
494
3017
PA6AG
NOMESCO Finland
Limited MRI examination of neck vasculature with high intensity magnet
16.0
23.6
38
24
Q61.3
ICD-10 Finland
Polycystic kidney, unspecified
14.0
23.5
40
29
N06AX11
ATC
mirtazapine; oral
1.5
23.3
910
6576
315
Kela drug reimbursment
Clopidogrel
10.6
22.8
44
42
S06.5
ICD-10 Finland
Traumatic subdural haemorrhage
3.9
22.7
95
249
Q28.2
ICD-10 Finland
Arteriovenous malformation of cerebral vessels
26.1
22.6
31
12
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.2
22.3
239
1135
PA2BM
NOMESCO Finland
MRI examination of vessels in the head with 3 Tesla magnet
63.0
21.9
25
*
I69.8
ICD-10 Finland
Sequelae of other and unspecified cerebrovascular diseases
63.0
21.9
25
*
R4120
NOMESCO Finland
Occupational therapy
2.5
21.8
177
730
N06AB04
ATC
citalopram; systemic
1.6
21.7
628
4203
N07BA03
ATC
varenicline; oral
2.6
21.6
166
666
R55
ICD-10 Finland
Syncope and collapse
2.0
21.5
294
1546
I67.2
ICD-10 Finland
Cerebral atherosclerosis
50.4
21.1
25
5
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.3
21.1
212
978
G46.3*I67.9
ICD-10 Finland
Brain stem stroke syndrome (I60-I67+)
+∞
20.9
20
*
I69.2
ICD-10 Finland
Sequelae of other nontraumatic intracranial haemorrhage
+∞
20.9
20
*
N01
ICPC
Headache
2.1
20.8
258
1307
I60.8
ICD-10 Finland
Other subarachnoid haemorrhage
211.3
20.6
21
*
PAN14
NOMESCO Finland
Plastic repair of arteries internal carotid artery
110.8
20.6
22
*
WX000
NOMESCO Finland
Monitoring vital functions without anesthesy
3.0
20.6
124
430
R1260
NOMESCO Finland
Evaluation of communicative skills
5.8
20.5
58
101
C09AA05
ATC
ramipril; oral
1.6
19.9
654
4504
Z01.8
ICD-10 Finland
Other specified special examinations
1.6
19.9
611
4139
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.9
19.9
325
1826
4309X
ICD-9 Finland
Subarachnoid haemorrhage[HAEMORRHAGIA SUBARACHNOIDALIS NUD]
+∞
19.8
19
*
Z82.3
ICD-10 Finland
Family history of stroke
15.4
19.7
32
21
PA6AD
NOMESCO Finland
CT of neck arteries
6.8
19.5
49
73
C09AA02
ATC
enalapril; systemic
1.6
19.3
551
3661
XFP96
NOMESCO Finland
Other intraoperative electrophysiological investigation in arhythmia or disturbance of impulse propagation
4.0
19.3
77
194
A02BC03
ATC
lansoprazole; oral
1.5
19.2
854
6300
C09CA01
ATC
losartan; oral
1.5
19.2
681
4778
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.3
19.0
177
786
ZXA00
NOMESCO Finland
Right side
1.5
19.0
782
5669
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.5
19.0
158
664
F32.9
ICD-10 Finland
Depressive episode, unspecified
1.9
19.0
311
1749
G40.20
ICD-10 Finland
Complex partial seizures with only alteration of consciousness
6.5
19.0
49
76
G45.3
ICD-10 Finland
Amaurosis fugax
4.3
19.0
70
164
G81.9
ICD-10 Finland
Hemiplegia, unspecified
7.1
18.8
46
66
TPH07
NOMESCO Finland
Cathetrisation of artery
1.9
18.8
292
1609
4380A
ICD-9 Finland
Late effects of cerebrovascular disease[SEQUELAE MORBI CEREBROVASCULARIS]
+∞
18.8
18
*
PA7CC
NOMESCO Finland
Very extensive angiography of arteries of neck and brain
100.7
18.6
20
*
AAL10
NOMESCO Finland
Intracranial endovascular thrombolysis
191.1
18.5
19
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
18.5
781
5690
N05AH04
ATC
quetiapine; oral
1.7
18.2
419
2623
N06AB10
ATC
escitalopram; oral
1.6
18.1
515
3415
XX1ZW
NOMESCO Finland
Very extensive written report from radiologist
13.0
17.9
31
24
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.1
17.9
208
1023
R90.8
ICD-10 Finland
Other abnormal findings on diagnostic imaging of central nervous system
5.8
17.8
50
87
N05CF01
ATC
zopiclone; oral
1.5
17.8
903
6825
R53
ICD-10 Finland
Malaise and fatigue
1.6
17.8
540
3639
R47.0
ICD-10 Finland
Dysphasia and aphasia
11.1
17.7
33
30
R4110
NOMESCO Finland
Physiotherapy
1.5
17.5
727
5266
N06AA09
ATC
amitriptyline; systemic
1.8
17.5
316
1832
I64
ICD-10 Finland
Stroke, not specified as haemorrhage or infarction
28.9
17.4
23
8
WW200
SPAT
NA
1.8
17.3
300
1716
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
17.2
572
3939
C09CA06
ATC
candesartan; oral
1.5
17.1
626
4404
Z00.0
ICD-10 Finland
General medical examination
1.6
17.0
495
3293
TPX22
NOMESCO Finland
Intravenous arterial thrombolysis
25.7
16.9
23
9
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.0
16.7
223
1160
J44.8
ICD-10 Finland
Other specified chronic obstructive pulmonary disease
1.9
16.7
249
1352
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.5
16.7
594
4150
I67.6
ICD-10 Finland
Nonpyogenic thrombosis of intracranial venous system
+∞
16.7
16
*
AAD10
NOMESCO Finland
Evacuation of chronic subdural haematoma
6.9
16.7
41
60
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.6
16.6
540
3695
NK6AI
NOMESCO Finland
Other cone beam scan
27.7
16.5
22
8
R03BB04
ATC
tiotropium bromide; inhalant
1.9
16.4
271
1525
R41.0
ICD-10 Finland
Disorientation, unspecified
3.2
16.3
87
279
N03AX12
ATC
gabapentin; oral
1.6
16.3
442
2888
R06.0
ICD-10 Finland
Dyspnoea
1.5
16.1
662
4769
N05BA01
ATC
diazepam; systemic, rectal
1.7
16.0
375
2355
N06AX16
ATC
venlafaxine; oral
1.7
15.9
379
2389
SPAT1292
SPAT
Other function in accordance with SHToL (Finnish classification of nursing interventions)
1.9
15.9
256
1430
WX872
NOMESCO Finland
Intensive care
2.4
15.8
136
580
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.2
15.8
172
823
H93.1
ICD-10 Finland
Tinnitus
2.0
15.7
198
1008
I60.5
ICD-10 Finland
Subarachnoid haemorrhage from vertebral artery
+∞
15.6
15
*
I61.8
ICD-10 Finland
Other intracerebral haemorrhage
+∞
15.6
15
*
TPH04
NOMESCO Finland
Cathetrisation of vein
1.5
15.6
561
3925
H02AB06
ATC
prednisolone; systemic
1.4
15.5
1298
10675
N19
ICPC
Speech disorder
6.9
15.4
38
56
J69.0
ICD-10 Finland
Pneumonitis due to food and vomit
4.6
15.4
53
117
N06CA01
ATC
amitriptyline and psycholeptics; systemic
1.8
15.4
304
1812
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.4
15.4
800
6043
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
2.2
15.2
164
782
SPAT1216
SPAT
Assessment of functional ability
1.6
15.2
404
2621
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.5
15.2
575
4065
A02BC02
ATC
pantoprazole; systemic
1.4
15.1
1854
16203
Z72.0
ICD-10 Finland
Tobacco use
3.2
15.0
79
252
M54.5
ICD-10 Finland
Low back pain
1.4
15.0
882
6812
R07.4
ICD-10 Finland
Chest pain, unspecified
1.4
15.0
741
5541
N05BA04
ATC
oxazepam; oral
1.5
14.9
682
5015
M03BX02
ATC
tizanidine; oral
1.4
14.9
1769
15359
H49.2
ICD-10 Finland
Sixth [abducent] nerve palsy
7.0
14.8
36
52
FP1B5
NOMESCO Finland
Resting ECG, 12 leads
4.3
14.8
55
131
M79.6
ICD-10 Finland
Pain in limb
1.4
14.8
984
7765
N03AX16
ATC
pregabalin; oral
1.5
14.8
656
4793
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
1.6
14.7
443
2968
I72.8
ICD-10 Finland
Aneurysm and dissection of other specified arteries
10.5
14.7
28
27
4340A
ICD-9 Finland
Occlusion of cerebral arteries, Cerebral thrombosis
+∞
14.6
14
*
AA1BD
NOMESCO Finland
Extensive CT of head and brain
3.1
14.6
83
277
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.4
14.5
931
7294
T36
ICD-10 Finland
Poisoning by systemic antibiotics
2.5
14.4
118
492
R11
ICD-10 Finland
Nausea and vomiting
1.9
14.4
209
1124
G40.12
ICD-10 Finland
Simple partial seizures with secondary generalization
7.9
14.3
32
41
N02AJ06
ATC
codeine and paracetamol; systemic
1.4
14.2
1003
7981
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
14.2
802
6139
XX3DW
NOMESCO Finland
Time consuming IT work
1.7
14.1
292
1769
C08CA13
ATC
lercanidipine; oral
1.6
14.1
368
2379
Z71.8
ICD-10 Finland
Other specified counselling
1.5
13.9
596
4319
AA1DM
NOMESCO Finland
Very extensive MRI examination of brain with 3 Tesla magnet
6.1
13.9
37
61
N03AX11
ATC
topiramate; oral
3.1
13.9
76
250
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
1.9
13.8
210
1148
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.6
13.8
439
2978
C03CA01
ATC
furosemide; systemic
1.4
13.8
683
5092
C08CA05
ATC
nifedipine; systemic
2.0
13.8
176
902
W19
ICD-10 Finland
Unspecified fall
1.8
13.7
233
1324
AA1CD
NOMESCO Finland
Very extensive CT of head and brain
3.4
13.7
65
193
I61.5
ICD-10 Finland
Intracerebral haemorrhage, intraventricular
+∞
13.5
13
*
PA6BG
NOMESCO Finland
MRI examination of neck vasculature with high intensity magnet
8.4
13.5
29
35
S18
ICPC
Laceration/cut
1.3
13.3
1164
9564
SPAT1153
SPAT
Removal of sutures
1.4
13.3
895
7047
G91.9
ICD-10 Finland
Hydrocephalus, unspecified
9.7
13.2
26
27
G40.2
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
6.9
13.1
32
47
UJF32
NOMESCO Finland
Coloscopy
1.4
13.1
696
5256
P20
ICPC
Memory disturbance
1.7
12.9
286
1762
AN1
HP
Coronary angiography
1.7
12.8
292
1815
A06AD11
ATC
lactulose; oral
1.6
12.8
351
2292
M03BX01
ATC
baclofen; systemic
3.6
12.7
57
162
-
ICD-10 Finland
NA
2.7
12.7
85
320
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
1.6
12.6
335
2169
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
2.2
12.6
124
570
I65.0
ICD-10 Finland
Occlusion and stenosis of vertebral artery
+∞
12.5
12
*
PA7KT
NOMESCO Finland
Temporary closure of brain artery
+∞
12.5
12
*
I62.1
ICD-10 Finland
Nontraumatic extradural haemorrhage
+∞
12.5
12
*
G46.4*I67.9
ICD-10 Finland
Cerebellar stroke syndrome
+∞
12.5
12
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
1.6
12.5
312
1992
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
2.3
12.5
115
513
N03AE01
ATC
clonazepam; systemic
2.0
12.3
159
820
CS444
NOMESCO Finland
Visual field testing with Octopus automated perimetry
2.6
12.3
90
356
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.3
12.2
110
484
C02AC05
ATC
moxonidine; oral
2.2
12.2
125
583
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.0
12.1
149
754
J01MA02
ATC
ciprofloxacin; systemic
1.3
12.1
1034
8431
M03BC01
ATC
orphenadrine (citrate); systemic
1.4
12.1
620
4639
Z94.0
ICD-10 Finland
Kidney transplant status
4.2
12.1
45
109
N03AX09
ATC
lamotrigine; oral
2.2
12.0
120
555
SPAT1229
SPAT
Assessment of need for aid
1.8
12.0
201
1137
A28
ICPC
Limited function/disability NOS
1.6
12.0
351
2330
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
1.9
12.0
168
892
S06.0
ICD-10 Finland
Concussion
1.7
12.0
249
1509
SPAT1217
SPAT
Assessment of need for services (elderly/care support)
1.9
11.8
164
868
ZYC01
SPAT
NA
2.0
11.7
143
719
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
2.5
11.7
89
361
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.4
11.6
777
6085
I71.4
ICD-10 Finland
Abdominal aortic aneurysm, without mention of rupture
3.3
11.6
58
180
AAF20
NOMESCO Finland
Revision of shunt of ventricle of brain
12.6
11.6
20
16
I67.3
ICD-10 Finland
Progressive vascular leukoencephalopathy
12.6
11.6
20
16
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.5
11.6
388
2660
43099
ICD-8 Finland
Subarachnoid haemorrhage, Without mention of hypertension
+∞
11.5
11
*
I65.3
ICD-10 Finland
Occlusion and stenosis of multiple and bilateral precerebral arteries
+∞
11.5
11
*
AAC20
NOMESCO Finland
Anastomosis to intracranial vessel
+∞
11.5
11
*
AAB30
NOMESCO Finland
Evacuation of spontaneous intracranial haematoma
+∞
11.5
11
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.5
11.3
435
3073
R51.81
ICD-10 Finland
Facial pain NOS
2.7
11.2
74
274
M54.4
ICD-10 Finland
Lumbago with sciatica
1.5
11.2
426
3001
N17
ICPC
Vertigo/dizziness
1.6
11.2
269
1700
A02BC05
ATC
esomeprazole; systemic
1.3
11.1
1129
9420
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.6
11.0
297
1933
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
1.8
11.0
190
1085
R50.9
ICD-10 Finland
Fever, unspecified
1.5
11.0
338
2270
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
4.0
11.0
42
105
SPAT1224
SPAT
Implementation of speech therapy rehabilitation plan
3.9
11.0
43
110
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.5
10.9
366
2506
WX730
NOMESCO Finland
Conventional respirator
3.6
10.8
47
131
A02BC01
ATC
omeprazole; systemic
1.4
10.8
742
5827
H53.9
ICD-10 Finland
Visual disturbance, unspecified
2.4
10.8
89
374
X59
ICD-10 Finland
Exposure to unspecified factor
1.5
10.8
437
3117
SPAT1310
SPAT
Counselling related to known health issue
1.3
10.8
844
6765
CS424
NOMESCO Finland
Visual field testing with Goldmann perimetry
5.4
10.7
31
58
C08CA02
ATC
felodipine; oral
1.7
10.7
237
1461
R4130
NOMESCO Finland
Speech therapy
3.3
10.7
51
154
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
4.5
10.6
36
80
SPAT1249
SPAT
Treatment-related counselling outside office
1.3
10.6
1041
8623
I69
ICD-10 Finland
Sequelae of cerebrovascular disease
60.2
10.6
12
*
SPAT1301
SPAT
No procedures
1.3
10.6
832
6671
J01DB01
ATC
cefalexin; oral
1.3
10.6
2328
21529
Z25.8
ICD-10 Finland
Need for immunization against other specified single viral diseases
0.6
10.6
126
2184
WX704
NOMESCO Finland
Intubation
1.8
10.5
191
1114
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.4
10.4
535
3994
PA7RT
NOMESCO Finland
Medical infusion to cerebral artery
110.4
10.4
11
*
J67.1
ICD-10 Finland
Bagassosis
+∞
10.4
10
*
G40.10
ICD-10 Finland
Simple partial seizures
5.9
10.4
28
48
G44.0
ICD-10 Finland
Cluster headache syndrome
4.1
10.4
39
96
H47.2
ICD-10 Finland
Optic atrophy
7.7
10.4
23
30
AAK00
NOMESCO Finland
Cranioplasty
32.6
10.3
13
*
WX110
NOMESCO Finland
Local anesthesy
1.3
10.3
1868
16777
N05BA09
ATC
clobazam; oral
8.2
10.3
22
27
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.6
10.3
241
1510
J01AA02
ATC
doxycycline; systemic
1.3
10.2
2269
20935
N30.0
ICD-10 Finland
Acute cystitis
1.5
10.2
345
2368
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
1.6
10.2
279
1824
J01DA01
ATC
[U] cefalexin; systemic
1.3
10.0
1727
15382
N06AX21
ATC
duloxetine; oral
1.6
10.0
278
1822
ZXA05
NOMESCO Finland
Left side
1.4
9.9
667
5210
R04.0
ICD-10 Finland
Epistaxis
1.8
9.9
174
1002
C10AX09
ATC
ezetimibe; oral
1.6
9.9
280
1843
J01EA01
ATC
trimethoprim; systemic
1.4
9.8
650
5067
G44.8
ICD-10 Finland
Other specified headache syndromes
3.8
9.8
40
107
J01FA06
ATC
roxithromycin; oral
1.3
9.8
1090
9168
S22.3
ICD-10 Finland
Fracture of rib
1.8
9.7
159
892
G50.1
ICD-10 Finland
Atypical facial pain
2.9
9.7
56
193
G50.0
ICD-10 Finland
Trigeminal neuralgia
3.0
9.6
53
178
127
Kela drug reimbursment
Transplant complication
3.2
9.6
49
156
F17.29
ICD-10 Finland
Addiction caused by tobacco UNS
2.8
9.6
58
207
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
2.7
9.5
61
225
PEF23
NOMESCO Finland
Thrombendarterectomy of femoral artery
3.5
9.5
42
120
C10AA07
ATC
rosuvastatin; oral
1.4
9.5
634
4949
PA6YT
NOMESCO Finland
Dilatation of carotid artery with stent
100.3
9.4
10
*
PA2VT
NOMESCO Finland
Intravascular evacuation of brain artery embolus
+∞
9.4
9
*
I62.9
ICD-10 Finland
Intracranial haemorrhage (nontraumatic), unspecified
+∞
9.4
9
*
I67.7
ICD-10 Finland
Cerebral arteritis, not elsewhere classified
+∞
9.4
9
*
H49.1
ICD-10 Finland
Fourth [trochlear] nerve palsy
6.2
9.4
24
39
C09BA02
ATC
enalapril and diuretics; systemic
1.6
9.3
222
1397
C03AA03
ATC
hydrochlorothiazide; oral
1.6
9.3
253
1651
H02AB04
ATC
methylprednisolone; systemic
1.4
9.3
392
2815
M48.0
ICD-10 Finland
Spinal stenosis
1.5
9.3
303
2065
P01AB01
ATC
metronidazole; oral, rectal
1.3
9.2
1063
8958
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
1.5
9.2
276
1840
N05CD07
ATC
temazepam; oral
1.5
9.2
308
2106
A12BA01
ATC
potassium chloride; oral
2.0
9.2
109
545
JA1AE
NOMESCO Finland
Ultrasound examination of groin and abdominal wall
3.1
9.2
48
156
W10
ICD-10 Finland
Fall on and from stairs and steps
1.9
9.2
124
655
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
1.7
9.1
172
1013
WZC05
NOMESCO Finland
Specialty-specific consultation based on referral by dentist or doctor
1.9
9.1
127
674
N02AA05
ATC
oxycodone; systemic
1.5
9.1
349
2456
R03AC02
ATC
salbutamol; inhalant
1.3
9.1
1399
12221
G51.0
ICD-10 Finland
Bell palsy
2.4
9.1
72
299
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.5
9.1
308
2116
SPAT1137
SPAT
Taking care of patient’s/customer’s hygiene
1.9
9.0
121
637
F10.09
ICD-10 Finland
Alcohol intoxication UNS
2.9
9.0
52
180
J44.9
ICD-10 Finland
Chronic obstructive pulmonary disease, unspecified
2.1
9.0
96
462
I95.1
ICD-10 Finland
Orthostatic hypotension
2.3
9.0
77
333
I67.8
ICD-10 Finland
Other specified cerebrovascular diseases
18.6
8.9
13
7
B01AC22
ATC
prasugrel; oral
7.4
8.9
20
27
ZXH09
SPAT
NA
2.8
8.9
56
203
SPAT1252
SPAT
Overall medication plan or its review
1.7
8.8
176
1054
M01AE03
ATC
ketoprofen; systemic, rectal
1.3
8.8
1008
8474
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
1.7
8.8
171
1018
R52.2
ICD-10 Finland
Other chronic pain
2.2
8.8
87
403
H02.4
ICD-10 Finland
Ptosis of eyelid
2.3
8.8
79
350
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.6
8.8
244
1598
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.4
8.8
512
3901
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
1.6
8.8
233
1509
SPAT1053
SPAT
Memory test
1.5
8.7
339
2395
H34.1
ICD-10 Finland
Central retinal artery occlusion
5.9
8.7
23
39
XX1XW
NOMESCO Finland
Extensive written report from radiologist
2.6
8.7
60
233
SPAT1240
SPAT
Therapeutic discussion
1.6
8.7
229
1482
4019X
ICD-9 Finland
Essential hypertension, Unspecified
2.4
8.6
67
277
SPAT1215
SPAT
Assessment of need for medical rehabilitation
2.0
8.6
107
547
S01.0
ICD-10 Finland
Open wound of scalp
1.7
8.6
165
977
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.5
8.6
273
1850
SPAT1254
SPAT
Administration of medicine
1.5
8.5
331
2339
EBA00
NOMESCO Finland
Extraction of tooth
1.3
8.5
796
6514
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
1.7
8.4
158
930
R07.3
ICD-10 Finland
Other chest pain
1.6
8.3
235
1546
AAC10
NOMESCO Finland
Reinforcement of intracranial aneurysm wall
+∞
8.3
8
*
I60
ICD-10 Finland
Subarachnoid haemorrhage
+∞
8.3
8
*
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
1.6
8.3
194
1214
SPAT1284
SPAT
Extensive health certificate
2.3
8.3
71
309
F51.0
ICD-10 Finland
Nonorganic insomnia
1.5
8.3
297
2065
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
3.5
8.3
37
108
M54.2
ICD-10 Finland
Cervicalgia
1.7
8.3
179
1101
SPAT1210
SPAT
Application of cast or individual aid
1.9
8.2
112
592
M79.1
ICD-10 Finland
Myalgia
1.5
8.2
302
2109
G40
ICD-10 Finland
Epilepsy
4.4
8.2
28
64
F06.7
ICD-10 Finland
Mild cognitive disorder
2.5
8.2
61
247
I48
ICD-10 Finland
Atrial fibrillation and flutter
1.4
8.2
475
3612
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.4
8.1
469
3564
N06AX03
ATC
mianserin; oral
1.8
8.1
126
699
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
1.4
8.0
381
2797
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
1.5
8.0
294
2053
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.3
8.0
688
5553
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
1.7
8.0
144
840
C07AA05
ATC
propranolol; systemic
1.4
8.0
489
3752
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
2.2
8.0
79
369
JN3AD
NOMESCO Finland
Abdominal CT examination
1.6
7.9
193
1223
SPAT1101
SPAT
Orthostatic test
2.0
7.9
103
536
XX4BW
NOMESCO Finland
NA
13.0
7.9
13
10
R1230
NOMESCO Finland
Neuropsychological evaluation of need and possibilities to rehabilitation
5.1
7.8
23
45
J15.9
ICD-10 Finland
Bacterial pneumonia, unspecified
1.6
7.8
186
1171
R13
ICD-10 Finland
Dysphagia
1.7
7.8
158
951
G40.19
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
5.7
7.8
21
37
183
Kela drug reimbursment
Lamotrigin and topiramate
4.3
7.8
27
63
C03DA01
ATC
spironolactone; oral
1.5
7.8
242
1632
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
1.8
7.7
133
764
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.0
7.7
96
493
N28
ICPC
Limited function/disability (N)
3.1
7.7
40
131
AAB00
NOMESCO Finland
Extirpation of intracranial lesion
3.2
7.7
38
120
C09DA06
ATC
candesartan and diuretics; oral
1.6
7.7
194
1242
G44.1
ICD-10 Finland
Vascular headache, not elsewhere classified
4.6
7.7
25
55
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
1.6
7.7
214
1407
SPAT1231
SPAT
Assessment of adjustments needed in living environment
2.7
7.6
50
190
J01CA04
ATC
amoxicillin; systemic
1.3
7.5
2221
20708
N30.9
ICD-10 Finland
Cystitis, unspecified
1.8
7.5
126
719
L02
ICPC
Back symptom/complaint
1.6
7.5
194
1250
A01
ICPC
Pain general/multiple sites
1.6
7.5
183
1162
H34.2
ICD-10 Finland
Other retinal artery occlusions
5.7
7.5
20
35
F10.31
ICD-10 Finland
Withdrawal symptoms caused by alcohol with seizures
4.3
7.5
26
61
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
2.6
7.5
52
203
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
2.0
7.5
87
435
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.3
7.5
506
3944
R52.9
ICD-10 Finland
Pain, unspecified
1.6
7.4
200
1304
I61.3
ICD-10 Finland
Intracerebral haemorrhage in brain stem
+∞
7.3
7
*
43399
ICD-8 Finland
Cerebral thrombosis, Without mention of hypertension
+∞
7.3
7
*
PA2JT
NOMESCO Finland
Very extensive embolisation of arterio-venous malformation of the brain
+∞
7.3
7
*
AAF15
NOMESCO Finland
Ventriculoatrial shunt
10.9
7.3
13
12
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
1.7
7.3
158
974
R47.1
ICD-10 Finland
Dysarthria and anarthria
4.9
7.3
22
45
D32.02
ICD-10 Finland
Benign tumor of the meninges at the base of the brain
3.5
7.3
31
88
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.4
7.2
363
2694
UJH02
NOMESCO Finland
Anoscopy
1.8
7.2
110
610
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.3
7.2
621
5009
I72.4
ICD-10 Finland
Aneurysm and dissection of artery of lower extremity
7.3
7.2
16
22
PA6AE
NOMESCO Finland
Ulrasound examination of neck vasculature
3.9
7.2
27
69
78551
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Symptomata abdominalis acuta NUD
2.0
7.1
82
407
I11.9
ICD-10 Finland
Hypertensive heart disease without (congestive) heart failure
1.9
7.1
97
516
TKC20
NOMESCO Finland
Catheterisation of bladder
1.7
7.1
148
903
PA6CG
NOMESCO Finland
Extensive MRI examination of neck vasculature with high intensity magnet
6.6
7.1
17
26
N07BB01
ATC
disulfiram; oral
1.9
7.1
103
561
G43.3
ICD-10 Finland
Complicated migraine
3.0
7.1
38
128
G43.8
ICD-10 Finland
Other migraine
3.0
7.1
38
128
J44.0
ICD-10 Finland
Chronic obstructive pulmonary disease with acute lower respiratory infection
1.9
7.1
95
503
ZXH06
SPAT
NA
2.2
7.1
68
315
J01FF01
ATC
clindamycin; systemic
1.3
7.0
672
5492
M54.6
ICD-10 Finland
Pain in thoracic spine
1.6
7.0
157
974
M53.0
ICD-10 Finland
Cervicocranial syndrome
1.5
7.0
201
1331
SPAT1100
SPAT
Long-term monitoring of blood pressure
1.6
7.0
168
1061
G91.1
ICD-10 Finland
Obstructive hydrocephalus
7.0
7.0
16
23
L01
ICPC
Neck symptom/complaint
1.4
7.0
325
2377
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.4
7.0
427
3276
GBB00
NOMESCO Finland
Tracheostomy
3.7
6.9
28
76
C10AA04
ATC
fluvastatin; oral
1.5
6.9
213
1430
D32.00
ICD-10 Finland
Benign tumor of the meninges on the outer surface of the cerebrum
2.8
6.9
41
147
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.3
6.9
522
4134
N29
ICPC
Neurological sympt/complt other
2.7
6.9
45
171
D35.2
ICD-10 Finland
Benign neoplasm: Pituitary gland
3.3
6.8
32
98
C01DA14
ATC
isosorbide mononitrate; oral
1.4
6.8
299
2162
X58
ICD-10 Finland
Exposure to other specified factors
1.4
6.8
304
2209
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.2
6.8
1030
8894
SPAT1307
SPAT
Psychosocial counselling and guidance
1.8
6.8
102
562
RS221
NOMESCO Finland
NA
3.0
6.7
35
116
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.5
6.7
248
1733
K89
ICPC
Transient cerebral ischaemia
4.1
6.7
24
59
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.3
6.6
563
4527
F10.26
ICD-10 Finland
Alcohol dependence periodic alcoholism
2.8
6.6
40
146
I70.9
ICD-10 Finland
Generalized and unspecified atherosclerosis
3.0
6.6
35
118
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.5
6.6
200
1340
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.3
6.6
411
3163
WX402
NOMESCO Finland
General anaesthesia
1.4
6.6
403
3089
N89
ICPC
Migraine
2.4
6.5
53
227
A01AB09
ATC
miconazole; local oral
1.5
6.5
217
1489
S09.9
ICD-10 Finland
Unspecified injury of head
3.2
6.5
31
97
PA2CM
NOMESCO Finland
Extensive MRI examination of vessels in the head with 3 Tesla magnet
70.0
6.4
7
*
2132
FHL
Ventricular operators sunt
70.0
6.4
7
*
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
3.2
6.4
31
98
PA2DG
NOMESCO Finland
Very extensive MRI examination of vessels in the head with high intensity magnet
14.3
6.4
10
7
75310
ICD-8 Finland
Congenital anomalies of urinary system, Ren polycysticus bilateralis
14.3
6.4
10
7
P15
ICPC
Chronic alcohol abuse
2.2
6.4
61
284
Z02.7
ICD-10 Finland
Issue of medical certificate
1.7
6.4
129
782
N06AB06
ATC
sertraline; oral
1.5
6.3
242
1707
AAF25
NOMESCO Finland
Removal of shunt of ventricle of brain
11.0
6.3
11
10
ZY010
SPAT
NA
3.2
6.3
30
94
AA7AA
NOMESCO Finland
Liquor cerebri shunt X-ray examinatin without contrast
9.3
6.3
12
13
TAA40
NOMESCO Finland
Cathetrisation of cerebrospinal fluid through skin
9.3
6.3
12
13
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
2.2
6.3
57
258
A11CC03
ATC
alfacalcidol; systemic
2.3
6.3
55
246
A04
ICPC
Weakness/tiredness general
1.4
6.3
274
1984
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.3
6.3
670
5549
I61.4
ICD-10 Finland
Intracerebral haemorrhage in cerebellum
+∞
6.2
6
*
PA1AC
NOMESCO Finland
Aortocervical angiongraphy with X-ray
+∞
6.2
6
*
I67
ICD-10 Finland
Other cerebrovascular diseases
+∞
6.2
6
*
2164
FHL
Crotigree
+∞
6.2
6
*
I67.5
ICD-10 Finland
Moyamoya disease
+∞
6.2
6
*
OAB47
SPAT
NA
2.4
6.2
49
208
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
1.5
6.2
206
1408
C08DA01
ATC
verapamil; systemic
1.8
6.2
101
573
E10.7
ICD-10 Finland
Type 1 diabetes mellitus, With multiple complications
0.1
6.2
*
235
F10.39
ICD-10 Finland
Withdrawal symptoms caused by alcohol UNS
3.1
6.2
31
101
I74.3
ICD-10 Finland
Embolism and thrombosis of arteries of lower extremities
3.6
6.2
25
69
K92.1
ICD-10 Finland
Melaena
1.7
6.2
108
627
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
1.9
6.1
79
413
K59.09
ICD-10 Finland
Constipation, unspecified
1.6
6.1
132
816
N05CF02
ATC
zolpidem; oral
1.3
6.1
430
3366
T90.5
ICD-10 Finland
Sequelae of intracranial injury
2.9
6.1
33
113
SPF00
NOMESCO Finland
Repatation of teeth prosthesis
2.0
6.1
70
349
C07AG02
ATC
carvedilol; oral
1.6
6.1
135
840
EBA15
NOMESCO Finland
Extraction of large number of teeth
1.9
6.1
85
458
L04AA06
ATC
mycophenolic acid; systemic
2.4
6.1
47
197
S06.6
ICD-10 Finland
Traumatic subarachnoid haemorrhage
3.7
6.1
24
65
SPAT1312
SPAT
General health counselling
1.2
6.0
775
6552
G40.1
ICD-10 Finland
Localization-related (focal)(partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
8.6
6.0
12
14
SPAT1234
SPAT
Support of social functional capacity
1.8
6.0
105
608
R60.0
ICD-10 Finland
Localized oedema
1.4
6.0
256
1844
K86
ICPC
Hypertension uncomplicated
1.4
6.0
284
2081
G40.00
ICD-10 Finland
Benign childhood epilepsy with centrotemporal EEG spikes
10.0
6.0
11
11
F80.1
ICD-10 Finland
Expressive language disorder
5.2
6.0
17
33

Mortality – FinRegistry

Association

Association between endpoint I9_ANEURYSM and mortality.

Females

Parameter HR [95% CI] p-value
I9_ANEURYSM 2.021 [1.8, 2.27] < 0.001
Birth year 0.996 [0.99, 1.0] 0.366

During the follow-up period (1.1.1998 — 31.12.2019), 1412 out of 8126 females with I9_ANEURYSM died.

Males

Parameter HR [95% CI] p-value
I9_ANEURYSM 1.977 [1.76, 2.22] < 0.001
Birth year 0.989 [0.98, 1.0] 0.018

During the follow-up period (1.1.1998 — 31.12.2019), 1268 out of 5324 males with I9_ANEURYSM died.

Mortality risk

Mortality risk for people of age

years, who have I9_ANEURYSM.

N-year risk Females Males
1 0.174% 0.347%
5 1.132% 2.357%
10 3.003% 6.196%
15 5.76% 11.634%
20 9.92% 19.211%

Relationships between endpoints

Index endpoint: I9_ANEURYSM – Cerebral aneurysm, nonruptured

GWS hits: 4

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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