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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Ototoxic hearing loss, drug-induced

H8_HL_OTOTOX_ADVERSE

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ATC codes for adverse effects of Drugs ANY
  • Hospital discharge: ICD-10 H91.0#

1 out of 7 registries used, show all original rules.

5

4. Check minimum number of events

None

5

5. Include endpoints

None

5

6. Filter based on genotype QC (FinnGen only)

5

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
C
First used in FinnGen datafreeze
DF5
Parent code in ICD-10
H91
Name in latin
Hypacusis ototoxica

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (not available in FinRegistry).

-FinnGen-

Key figures

All Female Male
Number of individuals 5 - -
Unadjusted period prevalence (%) 0.00 - -
Median age at first event (years) 49.49 - -

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
0
16
0.00
0.51
0.0
2.1
—
—
—
0
0
5
35
+∞
0.51
20.2
23.0
14.1
13.8
%
—
5
35
0
11
0.00
0.24
0.0
4.6
—
—
—
0
0
0
9
0.00
0.24
0.0
1.8
—
26.6
—
0
9
5
41
+∞
0.24
20.8
19.6
—
—
—
0
0
0
9
0.00
0.24
0.0
1.2
—
—
—
0
0
5
41
+∞
0.24
22.6
16.3
27.8
24.6
mg/l
—
5
34
5
43
+∞
0.00
22.2
18.9
86.0
83.4
umol/l
—
5
43
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
0.00
0.0
2.5
—
—
—
0
0
0
5
0.00
0.00
0.0
2.6
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (not available in FinRegistry).

Relationships between endpoints

Index endpoint: H8_HL_OTOTOX_ADVERSE – Ototoxic hearing loss, drug-induced

GWS hits: -

This endpoint is excluded (not available in FinRegistry).