Dystonia

G6_DYSTON

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 G24
  • Hospital discharge: ICD-9 3336
  • Hospital discharge: ICD-8 33100
  • Cause of death: ICD-10 G24
  • Cause of death: ICD-9 3336
  • Cause of death: ICD-8 33100

2 out of 7 registries used, show all original rules.

2111

4. Check minimum number of events

None

2111

5. Include endpoints

None

2111

6. Filter based on genotype QC (FinnGen only)

2111

Control definitions (FinnGen only)

Control exclude
G6_XTRAPYR

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
G20-G26
Name in latin
Dystonia muscularis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 15846 9900 5874
Only index persons 14517 9295 5222
Unadjusted period prevalence (%)
Whole population 0.24 0.28 0.16
Only index persons 0.29 0.34 0.20
Median age at first event (years)
Whole population 50.85 52.83 47.52
Only index persons 51.18 52.81 48.27

-FinnGen-

Key figures

All Female Male
Number of individuals 2111 1500 611
Unadjusted period prevalence (%) 0.44 0.51 0.27
Median age at first event (years) 53.20 52.38 55.24

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
1883
Matched controls
18829
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
G24.3
ICD-10 Finland
Spasmodic torticollis
1472.6
323.0
1026
15
N03AE01
ATC
clonazepam; systemic
36.3
323.0
874
438
G24.8
ICD-10 Finland
Other dystonia
4488.0
323.0
375
*
G24.9
ICD-10 Finland
Dystonia, unspecified
2039.8
323.0
459
*
G24.5
ICD-10 Finland
Blepharospasm
3347.8
315.5
296
*
3AX01
NOMESCO Finland
NA
202.6
256.6
262
15
ZX114
NOMESCO Finland
Intramuscular
42.1
250.0
314
89
C07AA05
ATC
propranolol; systemic
3.9
129.0
658
2254
G25.0
ICD-10 Finland
Essential tremor
34.2
126.4
166
53
N04BA02
ATC
levodopa and decarboxylase inhibitor; oral
43.5
125.3
156
39
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
15.5
116.7
198
142
M03BX01
ATC
baclofen; systemic
17.8
109.2
175
108
G24
ICD-10 Finland
Dystonia
+∞
108.4
103
*
G24.0
ICD-10 Finland
Drug-induced dystonia
+∞
106.3
101
*
G51.3
ICD-10 Finland
Clonic hemifacial spasm
68.6
95.8
110
17
N03AX12
ATC
gabapentin; oral
3.6
88.7
480
1644
M03AX01
ATC
botulinum toxin; parenteral
21.2
84.7
127
64
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
4.6
84.1
320
794
N04AA02
ATC
biperiden; systemic
15.1
77.1
131
93
110
Kela drug reimbursment
Parkinson's disease and comparable movement disrorders
+∞
75.5
72
*
G24.4
ICD-10 Finland
Idiopathic orofacial dystonia
+∞
72.3
69
*
R25.1
ICD-10 Finland
Tremor, unspecified
11.6
69.9
134
124
G20
ICD-10 Finland
Parkinson disease
173.5
64.4
67
*
G24.1
ICD-10 Finland
Idiopathic familial dystonia
+∞
63.9
61
*
TAW99
NOMESCO Finland
Other minor neurosurgical procedure
28.1
62.7
86
32
L01
ICPC
Neck symptom/complaint
3.1
61.4
404
1547
N03AX16
ATC
pregabalin; oral
2.5
60.0
579
2797
M03BX02
ATC
tizanidine; oral
2.2
56.8
1294
9345
N05BA04
ATC
oxazepam; oral
2.4
56.1
594
2993
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.8
55.6
256
742
N05BA01
ATC
diazepam; systemic, rectal
2.9
54.2
372
1452
R49.02
ICD-10 Finland
Spasmodic dysphonia
87.0
53.2
59
7
G25.8
ICD-10 Finland
Other specified extrapyramidal and movement disorders
+∞
52.3
50
*
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
4.7
51.4
188
438
N06AX21
ATC
duloxetine; oral
3.1
50.7
320
1176
AAG20
NOMESCO Finland
Stereotactic intracranial implantation of electrodes
511.1
50.7
50
*
G25.9
ICD-10 Finland
Extrapyramidal and movement disorder, unspecified
109.0
49.0
53
5
N06AX16
ATC
venlafaxine; oral
2.7
48.3
372
1550
G24.2
ICD-10 Finland
Idiopathic nonfamilial dystonia
+∞
48.1
46
*
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
4.1
44.8
189
504
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
3.2
43.9
256
885
M03BC01
ATC
orphenadrine (citrate); systemic
2.2
43.3
552
2975
N29
ICPC
Neurological sympt/complt other
9.0
43.0
93
108
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.9
40.7
278
1067
N06AB04
ATC
citalopram; systemic
2.2
40.6
500
2638
R51.80
ICD-10 Finland
Headache
2.5
40.3
359
1612
N99
ICPC
Neurological disease other
11.8
40.1
75
66
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
3.2
39.8
224
753
N05AH04
ATC
quetiapine; oral
2.5
39.4
372
1718
XA402
NOMESCO Finland
ENMG
5.6
38.1
116
220
DQD34
NOMESCO Finland
Treatment of spasmodic dysfonia
104.7
37.9
41
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.6
37.7
305
1290
AA1AD
NOMESCO Finland
CT of head and brain
2.2
36.8
475
2539
N06AX11
ATC
mirtazapine; oral
2.0
35.9
665
4116
R25.2
ICD-10 Finland
Cramp and spasm
6.5
35.2
94
151
N06AA09
ATC
amitriptyline; systemic
2.7
35.1
266
1082
N04BC05
ATC
pramipexole; oral
3.6
34.4
165
489
N03AG01
ATC
valproic acid; systemic, rectal
3.6
34.2
165
491
N05AD01
ATC
haloperidol; systemic
5.8
34.1
99
177
N05AH03
ATC
olanzapine; systemic
3.5
33.5
164
494
N05BA12
ATC
alprazolam; oral
2.6
32.8
259
1076
N06AB10
ATC
escitalopram; oral
2.1
32.3
444
2420
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.8
31.6
796
5417
N04BA03
ATC
levodopa, decarboxylase inhibitor and COMT inhibitor; oral
+∞
31.3
30
*
AEA50
NOMESCO Finland
Adjustment of implanted neurostimulator
28.6
31.2
42
15
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.5
31.0
268
1169
N03AF01
ATC
carbamazepine; oral, rectal
3.6
31.0
145
421
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.8
30.4
711
4707
R13
ICD-10 Finland
Dysphagia
3.2
30.2
169
561
G44.2
ICD-10 Finland
Tension-type headache
2.3
29.8
314
1512
A02BC02
ATC
pantoprazole; systemic
1.7
28.9
1211
9554
N04BD01
ATC
selegiline; oral
81.4
28.8
32
*
L28
ICPC
Limited function/disability (L)
2.2
27.7
310
1534
N03AX09
ATC
lamotrigine; oral
3.5
27.6
137
417
N06AB03
ATC
fluoxetine; oral
2.3
27.5
288
1380
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
2.5
27.3
235
1020
N28
ICPC
Limited function/disability (N)
7.5
27.3
65
89
TAB00
NOMESCO Finland
Lumbar puncture
3.7
27.1
125
358
R42
ICD-10 Finland
Dizziness and giddiness
2.0
26.9
426
2437
N87
ICPC
Parkinsonism
46.4
26.5
32
7
112
Kela drug reimbursment
Severe psychotic and other severe mental disorders
2.9
26.5
174
643
M54.2
ICD-10 Finland
Cervicalgia
2.8
26.4
179
677
H04.10
ICD-10 Finland
Dry eye syndrome
2.4
24.8
230
1037
N06AG02
ATC
moclobemide; oral
3.5
24.6
120
360
N02AX02
ATC
tramadol; systemic, rectal
1.7
24.3
776
5541
N05CF01
ATC
zopiclone; oral
1.7
24.2
597
3948
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
24.2
545
3502
A02BC05
ATC
esomeprazole; systemic
1.7
24.1
775
5542
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.6
24.0
188
773
M03BC51
ATC
orphenadrine, combinations; systemic
1.8
23.8
567
3707
N02BE01
ATC
paracetamol; systemic, rectal
1.9
23.7
1597
14060
3AX0X
NOMESCO Finland
NA
242.9
23.7
24
*
N03AX11
ATC
topiramate; oral
4.6
23.7
83
185
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
3.8
23.4
102
279
G43.3
ICD-10 Finland
Complicated migraine
6.0
23.4
65
111
G25.2
ICD-10 Finland
Other specified forms of tremor
47.3
23.3
28
6
AA1DG
NOMESCO Finland
Very extensive MRI examination of brain with high intensity magnet
4.6
23.1
82
185
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.8
23.0
555
3629
M79.6
ICD-10 Finland
Pain in limb
1.7
22.6
675
4702
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
22.2
411
2460
AEA00
NOMESCO Finland
Replacement of impulse generator of stimulation device in the nervous system
14.0
21.8
37
27
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
2.9
21.6
134
477
N03AA03
ATC
primidone; oral
116.4
21.6
23
*
M54.5
ICD-10 Finland
Low back pain
1.7
21.2
617
4249
R1250
NOMESCO Finland
Evaluation of functional capability
4.9
21.0
69
144
SPAT1229
SPAT
Assessment of need for aid
2.5
20.9
169
705
M43.6
ICD-10 Finland
Torticollis
9.7
20.8
42
44
R06.0
ICD-10 Finland
Dyspnoea
1.8
20.8
444
2782
A02BA02
ATC
ranitidine; systemic
1.9
20.4
367
2168
A06AC01
ATC
ispaghula (psylla seeds); oral
1.8
20.4
460
2927
XA800
NOMESCO Finland
Neuropsychological investigation
3.4
20.4
102
313
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.1
19.9
235
1181
TCE00
NOMESCO Finland
Therapeutic injection into extraocular muscle
+∞
19.8
19
*
F41.2
ICD-10 Finland
Mixed anxiety and depressive disorder
2.4
19.8
174
759
R52.2
ICD-10 Finland
Other chronic pain
3.6
19.7
90
257
N06AB06
ATC
sertraline; oral
2.1
19.6
230
1153
UJF32
NOMESCO Finland
Coloscopy
1.7
19.4
463
2993
P76
ICPC
Depressive disorder
2.7
19.4
134
512
F29
ICD-10 Finland
Unspecified nonorganic psychosis
3.4
19.3
95
288
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.6
19.1
737
5426
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
2.5
19.0
150
619
N05BA06
ATC
lorazepam; systemic, sublingual
3.1
18.9
107
359
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
18.8
848
6479
R52.9
ICD-10 Finland
Pain, unspecified
2.3
18.8
178
806
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.9
18.7
315
1816
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.5
18.5
152
639
R07.4
ICD-10 Finland
Chest pain, unspecified
1.7
18.4
475
3137
A01
ICPC
Pain general/multiple sites
2.4
18.4
162
707
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.5
18.1
874
6766
N05AX08
ATC
risperidone; systemic
2.5
18.1
149
626
T36
ICD-10 Finland
Poisoning by systemic antibiotics
3.0
18.1
108
375
R53
ICD-10 Finland
Malaise and fatigue
1.8
18.0
378
2343
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.4
17.6
155
677
N04BD02
ATC
rasagiline; oral
181.6
17.5
18
*
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
2.5
17.4
139
575
N08
ICPC
Abnormal involuntary movements
29.1
17.4
23
8
N04BC04
ATC
ropinirole; oral
18.8
17.3
26
14
K07.60
ICD-10 Finland
Snapping jaw
2.8
17.1
116
436
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
4.9
17.0
56
118
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.8
17.0
304
1786
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.3
16.9
156
699
N01
ICPC
Headache
2.1
16.8
204
1034
A02BC03
ATC
lansoprazole; oral
1.6
16.7
530
3682
P01
ICPC
Feeling anxious/nervous/tense
2.1
16.7
201
1014
193
Kela drug reimbursment
Rasagiline
+∞
16.7
16
*
A02BC01
ATC
omeprazole; systemic
1.6
16.7
496
3392
M79.1
ICD-10 Finland
Myalgia
1.9
16.7
254
1410
N05CD07
ATC
temazepam; oral
2.0
16.6
219
1150
A04
ICPC
Weakness/tiredness general
2.0
16.5
240
1308
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
1.9
16.5
276
1583
SPAT1240
SPAT
Therapeutic discussion
2.0
16.4
214
1118
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.6
16.4
124
500
L17
ICPC
Foot/toe symptom/complaint
1.7
16.3
447
2983
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
16.3
661
4877
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
2.3
16.1
151
681
F45.8
ICD-10 Finland
Other somatoform disorders
2.3
16.1
154
702
N05AX12
ATC
aripiprazole; systemic
3.1
16.1
91
305
N05AH02
ATC
clozapine; systemic
4.7
16.0
54
117
M50.3
ICD-10 Finland
Other cervical disc degeneration
3.6
15.9
72
205
F44.4
ICD-10 Finland
Dissociative motor disorders
33.7
15.7
20
6
3338X
ICD-9 Finland
Other extrapyramidal disease and abnormal movement disorders, Fragments of torsion dystonia
+∞
15.6
15
*
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
15.6
265
1526
TCA20
NOMESCO Finland
Peribulbar therapeutic injection into orbit
26.5
15.6
21
8
X69
ICD-10 Finland
Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
3.1
15.6
85
280
R4120
NOMESCO Finland
Occupational therapy
2.5
15.4
128
544
N05BE01
ATC
buspirone; oral
3.4
15.3
76
233
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
15.3
1269
10889
SPAT1215
SPAT
Assessment of need for medical rehabilitation
2.9
15.3
97
351
AA1BM
NOMESCO Finland
MRI examination of brain with 3 Tesla magnet
5.3
15.2
46
89
M53.0
ICD-10 Finland
Cervicocranial syndrome
2.1
15.1
177
885
R4130
NOMESCO Finland
Speech therapy
4.2
14.9
56
136
NA1AD
NOMESCO Finland
Cervical spine CT examination
2.9
14.9
91
323
N06AB05
ATC
paroxetine; oral
2.4
14.9
132
580
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
1.8
14.8
260
1511
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
2.7
14.7
104
404
N03AF02
ATC
oxcarbazepine; oral
3.4
14.7
72
219
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
2.4
14.7
128
556
R25.8
ICD-10 Finland
Other and unspecified abnormal involuntary movements
18.5
14.7
22
12
G43.9
ICD-10 Finland
Migraine, unspecified
2.4
14.6
125
540
WX110
NOMESCO Finland
Local anesthesy
1.5
14.5
1228
10511
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.1
14.4
166
824
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
14.4
322
2023
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.5
14.4
711
5440
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.6
14.4
107
426
J01DB01
ATC
cefalexin; oral
1.6
14.4
1479
13207
AA5EN
NOMESCO Finland
Brain reseptor or transprot protein distribution isotope imaging
27.4
14.3
19
7
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
3.3
14.3
71
219
H02AB06
ATC
prednisolone; systemic
1.5
14.2
809
6378
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
2.8
14.0
88
319
R03AC02
ATC
salbutamol; inhalant
1.5
14.0
950
7750
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
4.1
13.9
53
131
G25.3
ICD-10 Finland
Myoclonus
53.7
13.8
16
*
A28
ICPC
Limited function/disability NOS
1.8
13.6
230
1320
SPAT1216
SPAT
Assessment of functional ability
1.8
13.6
254
1507
N05AA02
ATC
levomepromazine; systemic
2.9
13.6
84
301
N07XX06
ATC
tetrabenazine; oral
+∞
13.6
13
*
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
2.2
13.5
138
648
N06AX12
ATC
bupropion; oral
2.3
13.5
121
536
TQA05
NOMESCO Finland
Puncture of skin of head or neck
141.0
13.5
14
*
S18
ICPC
Laceration/cut
1.5
13.4
693
5330
M54.6
ICD-10 Finland
Pain in thoracic spine
2.2
13.4
137
643
WVA30
NOMESCO Finland
Intramuscular and subcutaneous injection
21.3
13.3
19
9
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.0
13.3
182
965
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.4
13.3
931
7607
UDQ12
NOMESCO Finland
Flexible laryngoscopy
2.4
13.2
110
468
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.4
13.2
974
8034
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
1.9
13.2
204
1133
R10.1
ICD-10 Finland
Pain localized to upper abdomen
1.7
13.1
297
1869
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.8
13.0
228
1324
R20.2
ICD-10 Finland
Paraesthesia of skin
2.2
13.0
132
619
M01AB05
ATC
diclofenac; systemic, rectal
1.4
12.9
1190
10224
JC2KB
NOMESCO Finland
Functional X-ray examination of swallowing
6.2
12.9
34
56
F41.1
ICD-10 Finland
Generalized anxiety disorder
2.6
12.7
91
356
H53.1
ICD-10 Finland
Subjective visual disturbances
2.3
12.7
123
563
P01AB01
ATC
metronidazole; oral, rectal
1.4
12.6
726
5689
N06AX26
ATC
vortioxetine; oral
2.4
12.6
112
493
Z50.5
ICD-10 Finland
Speech therapy
5.2
12.6
38
74
R02
ICPC
Shortness of breath/dyspnoea
1.8
12.6
210
1200
L19
ICPC
Muscle symptom/complaint NOS
3.4
12.6
59
175
N05AB03
ATC
perphenazine; systemic, rectal
2.9
12.5
75
265
F99
ICD-10 Finland
Mental disorder, not otherwise specified
3.9
12.5
50
130
L03
ICPC
Low back symptom/complaint
1.6
12.4
418
2917
G54.0
ICD-10 Finland
Brachial plexus disorders
3.3
12.4
62
193
AA1CM
NOMESCO Finland
Extensive MRI examination of brain with 3 Tesla magnet
3.7
12.3
53
147
R26.8
ICD-10 Finland
Other and unspecified abnormalities of gait and mobility
4.2
12.2
45
108
M25.5
ICD-10 Finland
Pain in joint
1.5
12.1
503
3679
C07AB07
ATC
bisoprolol; oral
1.4
12.1
730
5759
R56.8
ICD-10 Finland
Other and unspecified convulsions
2.6
12.0
90
362
N05AF03
ATC
chlorprothixene; systemic
3.2
12.0
62
198
SPAT1254
SPAT
Administration of medicine
1.7
12.0
247
1509
SAA03
NOMESCO Finland
Extended examination of mouth
1.4
11.9
666
5174
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
2.8
11.9
76
280
R63.4
ICD-10 Finland
Abnormal weight loss
3.0
11.8
69
239
K02.1
ICD-10 Finland
Caries of dentine
1.4
11.8
978
8173
H02.4
ICD-10 Finland
Ptosis of eyelid
3.1
11.8
63
206
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
1.6
11.8
388
2690
Z71.8
ICD-10 Finland
Other specified counselling
1.5
11.7
406
2847
M01AE02
ATC
naproxen; oral, rectal
1.4
11.6
993
8333
AAH60
NOMESCO Finland
Microvascular decompression of cranial nerve
65.3
11.6
13
*
P29
ICPC
Psychological sympt/compl other
2.3
11.6
110
499
R25.3
ICD-10 Finland
Fasciculation
11.2
11.5
21
19
L02
ICPC
Back symptom/complaint
1.9
11.5
167
908
L29
ICPC
Musculoskeletal sympt/complt other
2.1
11.5
140
709
C07AB02
ATC
metoprolol; systemic
1.6
11.5
317
2100
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
1.9
11.4
172
948
M54.4
ICD-10 Finland
Lumbago with sciatica
1.6
11.4
293
1902
UKC02
NOMESCO Finland
Cystoscopy
1.7
11.4
231
1405
D21
ICPC
Swallowing problem
5.1
11.4
35
70
N06AA10
ATC
nortriptyline; systemic
3.4
11.4
53
157
P03
ICPC
Feeling depressed
1.9
11.3
165
900
N04BC09
ATC
rotigotine; transdermal
35.2
11.3
14
*
J01DA01
ATC
[U] cefalexin; systemic
1.4
11.2
1098
9412
SPAT1222
SPAT
Counselling/guidance promoting independent living
1.7
11.2
237
1458
F31.9
ICD-10 Finland
Bipolar affective disorder, unspecified
3.2
11.2
58
186
K30
ICD-10 Finland
Functional dyspepsia
1.8
11.2
195
1131
R47.1
ICD-10 Finland
Dysarthria and anarthria
6.8
11.1
27
40
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.7
11.1
241
1490
N06AA04
ATC
clomipramine; systemic
3.8
11.1
45
119
M79.0
ICD-10 Finland
Rheumatism, unspecified
2.5
11.0
85
349
R11
ICD-10 Finland
Nausea and vomiting
2.0
11.0
145
759
F40.1
ICD-10 Finland
Social phobias
3.4
11.0
53
161
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
11.0
1126
9715
KMAK
NOMESCO Finland
NA
1.4
11.0
903
7496
S06.0
ICD-10 Finland
Concussion
1.8
11.0
181
1030
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
5.1
10.9
33
65
-1
NOMESCO Finland
NA
1.4
10.9
573
4381
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.5
10.8
493
3663
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.4
10.8
743
5974
J01AA02
ATC
doxycycline; systemic
1.4
10.7
1380
12377
R4110
NOMESCO Finland
Physiotherapy
1.5
10.7
443
3223
R33
ICD-10 Finland
Retention of urine
2.2
10.7
107
501
R52.1
ICD-10 Finland
Chronic intractable pain
5.0
10.6
33
67
A06AD11
ATC
lactulose; oral
1.7
10.6
212
1279
R25.0
ICD-10 Finland
Abnormal head movements
60.3
10.6
12
*
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.5
10.5
393
2793
3007
Kela drug reimbursment
Erenumab and fremanezumab
5.1
10.5
32
64
H02.3
ICD-10 Finland
Blepharochalasis
2.1
10.4
117
575
G23.9
ICD-10 Finland
Degenerative disease of basal ganglia, unspecified
+∞
10.4
10
*
N04AA01
ATC
trihexyphenidyl; oral
+∞
10.4
10
*
WYA10
NOMESCO Finland
First aid or other corresponding healthcare contact
2.0
10.4
140
741
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
2.6
10.4
74
292
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.4
10.4
752
6089
F44.9
ICD-10 Finland
Dissociative [conversion] disorder, unspecified
12.1
10.3
18
15
N06AX03
ATC
mianserin; oral
2.3
10.3
92
408
N05AL01
ATC
sulpiride; systemic
4.0
10.3
40
102
P06
ICPC
Sleep disturbance
1.8
10.3
173
989
71720
ICD-8 Finland
Other nonarticular rheumatism, Torticollis not specified as congential, pyschogenic or traumatic
18.9
10.3
15
8
F95.9
ICD-10 Finland
Tic disorder, unspecified
23.5
10.2
14
6
N30.0
ICD-10 Finland
Acute cystitis
1.7
10.2
246
1569
M01AH05
ATC
etoricoxib; oral
1.4
10.1
1037
8881
L12
ICPC
Hand/finger symptom/complaint
1.7
10.1
242
1541
ZXM20
NOMESCO Finland
Intraoperative use of computerised tomography
6.9
10.1
24
35
SBB10
NOMESCO Finland
Teeth copy
2.1
10.1
117
585
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
2.4
10.0
82
349
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
2.6
10.0
74
296
F10.1
ICD-10 Finland
Mental and behavioural disorders due to use of alcohol, Harmful use
2.1
9.9
111
546
J01EA01
ATC
trimethoprim; systemic
1.5
9.8
438
3230
N05CF02
ATC
zolpidem; oral
1.6
9.8
314
2151
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.4
9.8
550
4240
F34.1
ICD-10 Finland
Dysthymia
2.6
9.8
71
283
SPAT1234
SPAT
Support of social functional capacity
2.3
9.8
86
379
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.6
9.8
253
1644
G47.3
ICD-10 Finland
Sleep apnoea
1.5
9.8
329
2281
M47.9
ICD-10 Finland
Spondylosis, unspecified
2.6
9.7
69
270
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
2.1
9.7
105
507
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.4
9.7
977
8326
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.6
9.6
296
2014
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.6
9.6
293
1989
R07.3
ICD-10 Finland
Other chest pain
1.8
9.5
156
886
N18
ICPC
Paralysis/weakness
3.9
9.5
38
100
L99
ICPC
Musculoskeletal disease other
3.4
9.5
44
131
A29
ICPC
General symptom/complaint other
1.7
9.5
182
1088
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
1.9
9.4
144
798
G21.9
ICD-10 Finland
Secondary parkinsonism, unspecified
+∞
9.4
9
*
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.0
9.4
126
667
M01AE03
ATC
ketoprofen; systemic, rectal
1.4
9.3
620
4917
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.5
9.3
317
2204
G50.1
ICD-10 Finland
Atypical facial pain
3.5
9.3
42
123
M01AX17
ATC
nimesulide; oral
1.5
9.3
400
2927
Z00.0
ICD-10 Finland
General medical examination
1.5
9.2
302
2080
SPAT1153
SPAT
Removal of sutures
1.4
9.2
514
3950
ZX112
NOMESCO Finland
Subcutaneous
3.1
9.2
48
157
R49.08
ICD-10 Finland
Other specified dysphonia
3.2
9.1
46
146
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
2.7
9.1
60
227
WX002
NOMESCO Finland
Sedation and analgesia
1.5
9.1
316
2204
F31.6
ICD-10 Finland
Bipolar affective disorder, current episode mixed
3.9
9.1
36
94
SPAT1224
SPAT
Implementation of speech therapy rehabilitation plan
4.2
9.1
33
80
TAC00
NOMESCO Finland
Peripheral nerve block
11.5
9.1
16
14
N06AA06
ATC
trimipramine; systemic
3.0
9.0
50
170
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
2.9
9.0
52
180
U01
ICPC
Dysuria/painful urination
1.9
9.0
131
713
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.4
9.0
495
3796
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
2.3
9.0
80
356
M48.0
ICD-10 Finland
Spinal stenosis
1.7
8.9
185
1128
F32.8
ICD-10 Finland
Other depressive episodes
3.7
8.9
37
101
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
3.0
8.9
51
175
M70.6
ICD-10 Finland
Trochanteric bursitis
1.6
8.9
215
1373
R55
ICD-10 Finland
Syncope and collapse
1.8
8.9
154
891
N05BA02
ATC
chlordiazepoxide; systemic
3.0
8.9
48
161
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.6
8.9
268
1811
G04BD12
ATC
mirabegron; oral
1.8
8.9
154
893
R51
ICD-10 Finland
Headache
2.1
8.8
98
480
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.4
8.8
671
5435
SPAT1263
SPAT
Sampling
1.4
8.7
703
5743
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.5
8.6
374
2732
J45.9
ICD-10 Finland
Asthma, unspecified
1.5
8.6
292
2023
F61.0
ICD-10 Finland
Mixed personality disorders
3.4
8.6
39
115
D01
ICPC
Abdominal pain/cramps general
1.7
8.6
180
1102
N05AN01
ATC
lithium; oral
3.0
8.6
49
168
N07BB01
ATC
disulfiram; oral
2.4
8.6
74
322
N02CC07
ATC
frovatriptan; oral
2.2
8.6
83
385
F60.30
ICD-10 Finland
Emotionally unstable personality disorder, impulsive
3.4
8.5
40
121
N31.9
ICD-10 Finland
Neuromuscular dysfunction of bladder, unspecified
5.0
8.5
26
53
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.7
8.5
184
1142
N07AA02
ATC
pyridostigmine; systemic
7.4
8.4
19
26
R47.8
ICD-10 Finland
Other and unspecified speech disturbances
5.7
8.4
23
41
1GB06
NOMESCO Finland
NA
90.4
8.4
9
*
H03AA01
ATC
levothyroxine sodium; systemic
1.4
8.4
402
2992
WX408
NOMESCO Finland
General anesthesy, balanced
1.4
8.4
437
3306
J31.0
ICD-10 Finland
Chronic rhinitis
1.8
8.4
132
740
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
3.1
8.4
43
139
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.7
8.4
183
1133
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
3.5
8.4
37
107
R05
ICPC
Cough
1.4
8.4
372
2734
SPAT1301
SPAT
No procedures
1.4
8.4
507
3943
F25.9
ICD-10 Finland
Schizoaffective disorder, unspecified
4.0
8.3
32
82
G25.6
ICD-10 Finland
Drug-induced tics and other tics of organic origin
+∞
8.3
8
*
G21.0
ICD-10 Finland
Malignant neuroleptic syndrome
+∞
8.3
8
*
R50.9
ICD-10 Finland
Fever, unspecified
1.6
8.3
215
1399
SPAT1249
SPAT
Treatment-related counselling outside office
1.4
8.3
658
5353
N39.4
ICD-10 Finland
Other specified urinary incontinence
1.8
8.3
138
788
R5599
NOMESCO Finland
Other rehabilitation service
2.7
8.2
53
198
XKD00
NOMESCO Finland
Uroflowmetry
1.7
8.2
175
1082
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
2.0
8.2
96
483
NAG40
NOMESCO Finland
Anterior fusion of cervical spine without fixation
2.7
8.2
53
200
P99
ICPC
Psychological disorders other
2.7
8.2
52
193
P74
ICPC
Anxiety disorder/anxiety state
2.4
8.1
67
288
RS221
NOMESCO Finland
NA
3.8
8.1
33
89
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
3.2
8.1
40
126
U04
ICPC
Incontinence urine
2.3
8.1
74
332
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.4
8.1
460
3535
N06AA12
ATC
doxepin; systemic
2.1
8.1
91
449
N02CC03
ATC
zolmitriptan; nasal, oral
2.0
8.1
104
543
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
2.7
8.1
52
195
SPAT1260
SPAT
Consultation of another employee
1.5
8.0
287
2014
XJC00
NOMESCO Finland
Oesophageal manometry
10.1
8.0
15
15
ABD30
NOMESCO Finland
Implantation of spinal stimulation device
5.3
8.0
23
44
R03AK08
ATC
formoterol and beclometasone; inhalant
2.3
8.0
70
308
F05.9
ICD-10 Finland
Delirium, unspecified
3.9
7.9
31
81
F32.3
ICD-10 Finland
Severe depressive episode with psychotic symptoms
2.9
7.9
46
161
S82
ICPC
Naevus/mole
1.6
7.9
194
1241
Z50.1
ICD-10 Finland
Other physical therapy
2.0
7.9
99
513
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
1.9
7.9
120
664
N02CC06
ATC
eletriptan; oral
2.3
7.9
70
311
XCW99
NOMESCO Finland
Other investigative procedure of eye
1.7
7.9
167
1026
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
2.9
7.9
45
155
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
1.6
7.9
209
1367
F43.1
ICD-10 Finland
Post-traumatic stress disorder
2.9
7.8
45
156
SPAT1310
SPAT
Counselling related to known health issue
1.4
7.8
517
4075
XKC03
NOMESCO Finland
Water cystometry
2.5
7.8
58
237
S40.0
ICD-10 Finland
Contusion of shoulder and upper arm
2.4
7.8
66
286
N05AA01
ATC
chlorpromazine; systemic, rectal
3.9
7.8
30
78
X59
ICD-10 Finland
Exposure to unspecified factor
1.5
7.7
287
2030
G43.8
ICD-10 Finland
Other migraine
3.7
7.6
31
84
M01AE01
ATC
ibuprofen; systemic, rectal
1.5
7.6
1619
15222
M54.1
ICD-10 Finland
Radiculopathy
2.2
7.6
71
323
R39.1
ICD-10 Finland
Other difficulties with micturition
2.9
7.6
44
154
IEY05
NOMESCO Finland
Dedicated profession-specific psychiatric intervention, individual
2.7
7.6
49
184
7235A
ICD-9 Finland
Other disorders of cervical region, Torticollis, unspecified
25.1
7.6
10
*
IGY02
NOMESCO Finland
Psychiatric monitoring contact
3.0
7.6
41
139
SHA04
NOMESCO Finland
Correction of physiology of bite - very demanding therapy visit
3.8
7.6
30
80
Z76.8
ICD-10 Finland
Persons encountering health services in other specified circumstances
2.4
7.5
62
266
R35
ICD-10 Finland
Polyuria
2.0
7.5
89
449
N31.2
ICD-10 Finland
Flaccid neuropathic bladder, not elsewhere classified
5.8
7.5
20
35
L83
ICPC
Neck syndrome
4.7
7.5
24
52
R74
ICPC
Upper respiratory infection acute
1.4
7.5
467
3642
N02CD01
ATC
erenumab; parenteral
4.8
7.5
23
48
N05AF01
ATC
flupentixol; systemic
3.2
7.4
37
119
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
1.9
7.4
108
590
T78.4
ICD-10 Finland
Allergy, unspecified
2.1
7.4
81
396
D12
ICPC
Constipation
2.5
7.4
55
225
F02.39*G20
ICD-10 Finland
Dementia in Parkinson's disease without information on additional symptoms
+∞
7.3
7
*
N04BX02
ATC
entacapone; oral
+∞
7.3
7
*
G25.5
ICD-10 Finland
Other chorea
+∞
7.3
7
*
M01AH01
ATC
celecoxib; oral (coxibs)
1.5
7.3
294
2112
R27.0
ICD-10 Finland
Ataxia, unspecified
6.8
7.3
17
25
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
1.8
7.3
126
730
IBA01
NOMESCO Finland
Diagnostic and symptom-mapping evaluation
3.9
7.3
28
73
G04CA02
ATC
tamsulosin; oral
1.6
7.2
211
1410
R2120
NOMESCO Finland
Counselling and guidance concerning rehabilitation services and social security
5.5
7.2
20
37
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
4.3
7.2
25
59
SXA20
NOMESCO Finland
Local application of medicine to mouth
1.9
7.2
95
502
AA1AG
NOMESCO Finland
Short MRI examination of brain with median intensity magnet
3.3
7.1
33
100
M01AG02
ATC
tolfenamic acid; oral, rectal
1.5
7.1
264
1865
M01AB55
ATC
diclofenac, combinations; oral
1.8
7.1
110
612
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
2.1
7.1
75
361
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
1.6
7.1
163
1026
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
1.8
7.1
119
681
R00.2
ICD-10 Finland
Palpitations
1.8
7.1
126
735
N05AE04
ATC
ziprasidone; systemic
6.0
7.1
18
30
XXA00
NOMESCO Finland
Clinical examination requiring general anaesthesia
6.0
7.1
18
30
SPAT1243
SPAT
Psychiatric/psychological examination
2.6
7.1
49
191
R05FB02
ATC
cough suppressants and expectorants
1.3
7.1
615
5045
A11
ICPC
Chest pain NOS
1.8
7.0
113
639
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
2.6
7.0
47
182
WX290
NOMESCO Finland
Other blockade of nerve
1.3
7.0
712
5967
J01FA10
ATC
azithromycin; systemic
1.3
7.0
1001
8796
G72.8
ICD-10 Finland
Other specified myopathies
3.8
7.0
27
71
M35.7
ICD-10 Finland
Hypermobility syndrome
3.3
6.9
32
97
A03FA01
ATC
metoclopramide; systemic, rectal
1.4
6.9
342
2556
H02AB07
ATC
prednisone; oral
1.5
6.9
231
1595
X78
ICD-10 Finland
Intentional self-harm by sharp object
6.3
6.9
17
27
L15
ICPC
Knee symptom/complaint
1.4
6.9
330
2451
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
1.6
6.9
193
1278
F45.0
ICD-10 Finland
Somatization disorder
5.9
6.9
18
31
F20.9
ICD-10 Finland
Schizophrenia, unspecified
2.9
6.9
38
131
G51.4
ICD-10 Finland
Facial myokymia
7.5
6.9
15
20
N06AX17
ATC
milnacipran; oral
3.7
6.9
28
77
L16
ICPC
Ankle symptom/complaint
1.6
6.9
165
1051
G03DC03
ATC
lynestrenol; oral
2.6
6.8
46
179
R01AD08
ATC
fluticasone; nasal
1.4
6.8
467
3687
K10.3
ICD-10 Finland
Alveolitis of jaws
2.0
6.8
78
391
Z76.0
ICD-10 Finland
Issue of repeat prescription
1.5
6.8
234
1627
NA7BG
NOMESCO Finland
Spine and spinal cord MRI examination with high intensity magnet
6.7
6.8
16
24
M89.0
ICD-10 Finland
Algoneurodystrophy
4.2
6.8
24
58
ZXA10
NOMESCO Finland
Bilateral
1.4
6.8
285
2062
J01CA04
ATC
amoxicillin; systemic
1.3
6.8
1410
13014
TKC22
NOMESCO Finland
Catheterisation instruction
2.9
6.8
39
136
Q79.6
ICD-10 Finland
Ehlers-Danlos syndrome
9.3
6.8
13
14
J01FA06
ATC
roxithromycin; oral
1.3
6.8
674
5627
N02AA05
ATC
oxycodone; systemic
1.5
6.8
202
1361
R21
ICPC
Throat symptom/complaint
1.4
6.8
310
2285
F32.01
ICD-10 Finland
Mild depressive episode with somatic syndrome
4.5
6.8
22
49
R49.01
ICD-10 Finland
Functional dysphonia
2.5
6.7
51
211
R01BA52
ATC
pseudoephedrine, combinations; oral
1.3
6.7
533
4305
TNX00
SPAT
NA
4.7
6.7
21
45
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.4
6.7
460
3635
U02
ICPC
Urinary frequency/urgency
1.5
6.7
211
1441
E23.09
ICD-10 Finland
Pituitary insufficiency NOS
22.6
6.7
9
*
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
1.6
6.6
161
1031
N17
ICPC
Vertigo/dizziness
1.6
6.6
164
1056
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
1.7
6.6
140
863
R05
ICD-10 Finland
Cough
1.4
6.6
306
2259
S89.9
ICD-10 Finland
Unspecified injury of lower leg
2.3
6.6
57
254
SAA04
NOMESCO Finland
Special inverstigation of mouth
1.9
6.6
94
512
F33.4
ICD-10 Finland
Recurrent depressive disorder, currently in remission
2.6
6.6
46
181
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
3.0
6.6
34
113
S29
ICPC
Skin symptom/complaint other
1.5
6.5
263
1888
UJF30
NOMESCO Finland
Ileoscopy through colon
1.6
6.5
152
964
N02CD03
ATC
fremanezumab; systemic
5.0
6.5
19
38
R1260
NOMESCO Finland
Evaluation of communicative skills
3.3
6.5
30
92
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
1.7
6.4
120
712
G21.1
ICD-10 Finland
Other drug-induced secondary parkinsonism
70.1
6.4
7
*
Z01.2
ICD-10 Finland
Dental examination
1.3
6.4
680
5715
F20.00
ICD-10 Finland
Paranoid schizophrenia continuous
2.8
6.4
38
137
G81.9
ICD-10 Finland
Hemiplegia, unspecified
4.3
6.4
22
52
NA1BM
NOMESCO Finland
Cervical spine MRI examination with 3 Tesla magnet
7.4
6.4
14
19
D06
ICPC
Abdominal pain localized other
1.7
6.4
132
810
M79.7
ICD-10 Finland
Fibromyalgia
2.1
6.4
67
322
J01FF01
ATC
clindamycin; systemic
1.4
6.4
414
3238
K08.80
ICD-10 Finland
Toothache NOS
1.7
6.4
128
779
F10.21
ICD-10 Finland
Alcohol dependence currently abstinent, but staying in restrictive environment
4.4
6.3
21
48
R03BB04
ATC
tiotropium bromide; inhalant
1.7
6.3
134
825
R30.0
ICD-10 Finland
Dysuria
2.3
6.3
55
246
R06.5
ICD-10 Finland
Mouth breathing
1.7
6.3
131
806
F45.9
ICD-10 Finland
Somatoform disorder, unspecified
11.1
6.3
11
10
X84
ICD-10 Finland
Intentional self-harm by unspecified means
9.3
6.3
12
13
F60.9
ICD-10 Finland
Personality disorder, unspecified
3.3
6.3
29
89
R60.9
ICD-10 Finland
Oedema, unspecified
2.0
6.3
73
368
3336A
ICD-9 Finland
Other extrapyramidal disease and abnormal movement disorders, Idiopathic torsion dystonia
+∞
6.3
6
*
G80.3
ICD-10 Finland
Dyskinetic cerebral palsy
+∞
6.3
6
*
M54.8
ICD-10 Finland
Other dorsalgia
2.1
6.2
66
319
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
1.6
6.2
141
885
F31.7
ICD-10 Finland
Bipolar affective disorder, currently in remission
2.8
6.2
36
128
A07AA02
ATC
nystatin; oral
1.8
6.2
102
583
TLC00
NOMESCO Finland
Insertion of intrauterine device
1.8
6.2
104
600
ICB01
NOMESCO Finland
Psychiatric treatment plan, standard
2.6
6.2
41
159
L08
ICPC
Shoulder symptom/complaint
1.4
6.2
290
2143
N06AX22
ATC
agomelatine; oral
2.6
6.2
42
166
SPAT1252
SPAT
Overall medication plan or its review
1.8
6.1
96
539
IGY02
SPAT
NA
7.7
6.1
13
17
N02CC05
ATC
almotriptan; oral
2.0
6.1
74
378
A01AB09
ATC
miconazole; local oral
1.6
6.1
142
900
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.5
6.1
232
1644
G97.0
ICD-10 Finland
Cerebrospinal fluid leak from spinal puncture
3.5
6.1
26
75
3018D
ICD-9 Finland
Personality disorders, Other personality disorders[EPÄVAKAA PERSOONALLISUUS]
4.7
6.1
19
41
K59.09
ICD-10 Finland
Constipation, unspecified
1.9
6.1
90
496
D11
ICPC
Diarrhoea
1.6
6.1
175
1167
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.3
6.1
423
3342
G04BD07
ATC
tolterodine; oral
1.9
6.1
82
437
TCC40
NOMESCO Finland
Closure of lacrimal canaliculus with plug
8.6
6.1
12
14
F31.5
ICD-10 Finland
Bipolar affective disorder, current episode severe depression with psychotic symptoms
4.9
6.0
18
37
XCK00
NOMESCO Finland
Perimetry
1.8
6.0
99
566
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.3
6.0
644
5411

Mortality – FinRegistry

Association

Association between endpoint G6_DYSTON and mortality.

Females

Parameter HR [95% CI] p-value
G6_DYSTON 1.359 [1.22, 1.51] < 0.001
Birth year 0.994 [0.99, 1.0] 0.159

During the follow-up period (1.1.1998 — 31.12.2019), 1215 out of 8826 females with G6_DYSTON died.

Males

Parameter HR [95% CI] p-value
G6_DYSTON 1.516 [1.35, 1.7] < 0.001
Birth year 0.984 [0.97, 0.99] 0.001

During the follow-up period (1.1.1998 — 31.12.2019), 866 out of 5233 males with G6_DYSTON died.

Mortality risk

Mortality risk for people of age

years, who have G6_DYSTON.

N-year risk Females Males
1 0.147% 0.251%
5 0.803% 1.471%
10 1.908% 3.745%
15 3.678% 7.496%
20 6.392% 12.402%

Relationships between endpoints

Index endpoint: G6_DYSTON – Dystonia

GWS hits: 1

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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