No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
564 |
4. Check minimum number of eventsNone |
564 |
5. Include endpointsNone |
564 |
6. Filter based on genotype QC (FinnGen only) |
564 |
Control definitions (FinnGen only)
- Control exclude
- M13_SOFTTISSUE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M71
- Name in latin
- Cystae bursales
Similar endpoints
↥List of similar endpoints to
Other bursal cyst
based on the number of shared cases.
Similar with more cases:
- Other bursopathies
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3159 | 1842 | 1306 |
| Only index persons | 3020 | 1776 | 1244 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.05 | 0.05 | 0.04 |
| Only index persons | 0.06 | 0.07 | 0.05 |
| Median age at first event (years) | |||
| Whole population | 54.38 | 54.65 | 54.01 |
| Only index persons | 54.03 | 54.25 | 53.71 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 564 | 342 | 222 |
| Unadjusted period prevalence (%) | 0.11 | 0.12 | 0.10 |
| Median age at first event (years) | 57.12 | 54.84 | 60.64 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 502
- Matched controls
- 5019
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M71.3
ICD-10 Finland
Other bursal cyst
4503599627370496.0
323.0
480
*
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
11.3
46.7
92
98
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
6.6
37.4
104
191
M75.1
ICD-10 Finland
Rotator cuff syndrome
4.9
35.5
131
336
N03AX16
ATC
pregabalin; oral
3.9
32.6
161
541
M48.0
ICD-10 Finland
Spinal stenosis
5.2
32.2
110
257
M67.4
ICD-10 Finland
Ganglion
11.3
32.2
62
62
M79.6
ICD-10 Finland
Pain in limb
3.2
28.7
190
792
N03AX12
ATC
gabapentin; oral
4.4
27.9
112
306
M54.4
ICD-10 Finland
Lumbago with sciatica
4.1
27.7
123
370
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
25.6
27.4
38
16
N02AX02
ATC
tramadol; systemic, rectal
2.8
26.4
248
1286
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
5.5
25.9
82
173
NHM20
NOMESCO Finland
Excision of synovial ganglion of ankle or foot
41.2
25.2
31
8
L03
ICPC
Low back symptom/complaint
3.2
24.7
156
617
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
4.0
24.3
109
328
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.6
23.3
255
1412
7275X
ICD-9 Finland
Other disorders of synovium, tendon and bursa, Rupture of synovium[CYSTA SYNOVIALIS ALIA LOCO DEFINITO]
+∞
23.1
22
*
NGM20
NOMESCO Finland
Excision of synovial ganglion of knee or lower leg
229.5
21.8
22
*
M25.5
ICD-10 Finland
Pain in joint
2.8
21.2
168
758
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.3
21.1
83
219
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
50.2
20.3
24
5
M01AH05
ATC
etoricoxib; oral
2.4
19.9
317
2079
QCA25
NOMESCO Finland
Destruction of lesion of skin of upper limb
30.3
19.8
26
9
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
11.3
19.7
37
35
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
9.7
19.2
39
43
SPAT1153
SPAT
Removal of sutures
2.5
18.1
189
982
H02AB06
ATC
prednisolone; systemic
2.3
17.2
249
1512
M19.0
ICD-10 Finland
Primary arthrosis of other joints
4.3
17.2
66
169
N02BE01
ATC
paracetamol; systemic, rectal
3.0
17.0
444
3609
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.4
15.4
159
810
M70.6
ICD-10 Finland
Trochanteric bursitis
3.5
15.0
74
236
M54.3
ICD-10 Finland
Sciatica
5.3
15.0
46
93
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
+∞
14.6
14
*
L17
ICPC
Foot/toe symptom/complaint
2.4
14.3
138
673
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
6.7
14.3
36
57
M54.5
ICD-10 Finland
Low back pain
2.3
14.0
169
921
ABC99
NOMESCO Finland
Other decompressive operation on spinal cord or nerve root
54.9
13.9
16
*
ZXC10
NOMESCO Finland
Use of laser
7.4
13.6
32
46
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.2
13.4
180
1024
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
4.1
13.4
53
140
J01DB01
ATC
cefalexin; oral
2.3
13.0
415
3372
G56.0
ICD-10 Finland
Carpal tunnel syndrome
3.0
12.9
77
282
Z01.8
ICD-10 Finland
Other specified special examinations
2.4
12.8
119
567
M01AC06
ATC
meloxicam; systemic, rectal
2.1
12.7
192
1143
S18
ICPC
Laceration/cut
2.0
12.5
216
1358
ABC16
NOMESCO Finland
Microsurgical excision of lumbar intervertebral disc displacement
5.2
12.3
38
78
L86
ICPC
Back syndrome with radiating pain
4.4
12.2
44
107
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.0
11.9
226
1465
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
4.2
11.7
44
111
ABC56
NOMESCO Finland
Decompression of lumbar spinal canal and nerve roots
7.6
11.4
26
36
N02AJ06
ATC
codeine and paracetamol; systemic
2.0
11.4
177
1055
J45.9
ICD-10 Finland
Asthma, unspecified
2.6
11.3
89
385
M03BX02
ATC
tizanidine; oral
1.9
11.3
304
2228
M01AB05
ATC
diclofenac; systemic, rectal
1.9
11.2
329
2483
NBA30
NOMESCO Finland
Exploration of joint of shoulder or upper arm, arthroscopic
20.6
11.2
16
8
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
4.3
11.1
41
102
M54.1
ICD-10 Finland
Radiculopathy
5.3
11.0
33
66
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
3.0
11.0
64
231
M79.0
ICD-10 Finland
Rheumatism, unspecified
18.3
10.8
16
9
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
2.9
10.7
69
264
NBL00
NOMESCO Finland
Suture or reinsertation of rotator cuff of shoulder
6.4
10.6
27
44
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
3.6
10.5
48
144
L12
ICPC
Hand/finger symptom/complaint
2.7
10.5
76
313
R51.80
ICD-10 Finland
Headache
2.7
10.4
74
301
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
3.9
10.4
42
114
L15
ICPC
Knee symptom/complaint
2.3
10.3
110
556
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
8.2
10.2
22
28
A02BC05
ATC
esomeprazole; systemic
1.9
10.2
204
1328
M43.1
ICD-10 Finland
Spondylolisthesis
5.0
10.1
32
68
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
17.1
9.9
15
9
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.2
9.7
108
553
J01AA02
ATC
doxycycline; systemic
2.0
9.7
389
3193
L08
ICPC
Shoulder symptom/complaint
2.3
9.6
91
434
9473
FHL
Local soft tissue removal or exploration (eg Bursa)
30.6
9.4
12
*
G44.2
ICD-10 Finland
Tension-type headache
2.6
9.4
69
286
J01FA10
ATC
azithromycin; systemic
1.8
9.4
277
2039
M17.1
ICD-10 Finland
Other primary gonarthrosis
2.2
9.2
103
527
M02AA07
ATC
piroxicam; topical
1.9
9.2
184
1187
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
8.5
9.1
19
23
NBG10
NOMESCO Finland
Acromioplastia
37.4
9.0
11
*
N06AX21
ATC
duloxetine; oral
2.8
8.9
59
229
G04BD12
ATC
mirabegron; oral
2.8
8.9
59
229
M65.8
ICD-10 Finland
Other synovitis and tenosynovitis
12.8
8.9
15
12
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
2.6
8.9
65
267
J01DA01
ATC
[U] cefalexin; systemic
1.8
8.9
308
2365
M01AE02
ATC
naproxen; oral, rectal
1.8
8.9
275
2039
SPAT1203
SPAT
Injection therapy, other than intramuscular or subcutaneous
4.7
8.8
29
65
N06AX11
ATC
mirtazapine; oral
1.9
8.8
151
919
M03BC01
ATC
orphenadrine (citrate); systemic
2.1
8.8
113
614
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
7.9
8.7
19
25
N06AA09
ATC
amitriptyline; systemic
2.9
8.6
53
197
J01CA04
ATC
amoxicillin; systemic
1.9
8.6
389
3243
J01FF01
ATC
clindamycin; systemic
2.0
8.5
135
795
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.6
8.4
60
245
M01AE03
ATC
ketoprofen; systemic, rectal
1.8
8.4
186
1233
N04BC05
ATC
pramipexole; oral
3.1
8.3
44
149
M71.2
ICD-10 Finland
Synovial cyst of popliteal space [Baker]
7.3
8.3
19
27
ZXA00
NOMESCO Finland
Right side
1.9
8.2
136
814
SPAT1301
SPAT
No procedures
1.9
8.1
155
975
J01MA02
ATC
ciprofloxacin; systemic
1.8
8.1
188
1262
NBF25
NOMESCO Finland
Operation for humeroscapular osteochondritis, arthroscopic
17.5
8.1
12
7
M01AX17
ATC
nimesulide; oral
2.0
8.1
117
666
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.6
8.1
61
258
M01AH02
ATC
rofecoxib; oral
2.4
8.0
71
324
M79.7
ICD-10 Finland
Fibromyalgia
7.4
8.0
18
25
M15
ICD-10 Finland
Polyarthrosis
4.0
8.0
31
82
M01AH01
ATC
celecoxib; oral (coxibs)
2.1
7.9
92
477
SPAT1312
SPAT
General health counselling
1.8
7.9
153
967
SAA01
NOMESCO Finland
Simple examination of mouth
1.7
7.8
328
2618
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
4.1
7.8
29
74
M77.1
ICD-10 Finland
Lateral epicondylitis
3.6
7.8
34
100
QCA40
NOMESCO Finland
Laser therapy or photocoagulation of skin of upper limb
45.7
7.7
9
*
M01AX05
ATC
glucosamine; oral
2.0
7.7
104
576
L13
ICPC
Hip symptom/complaint
2.2
7.6
78
383
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.4
7.5
35
108
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.9
7.5
134
821
L16
ICPC
Ankle symptom/complaint
2.7
7.5
49
191
M20.1
ICD-10 Finland
Hallux valgus (acquired)
2.8
7.4
46
172
A02BC03
ATC
lansoprazole; oral
1.8
7.4
140
876
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
3.3
7.3
36
116
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.9
7.3
129
787
R52.1
ICD-10 Finland
Chronic intractable pain
16.0
7.3
11
7
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
2.3
7.2
67
315
J01FA06
ATC
roxithromycin; oral
1.7
7.2
197
1377
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
3.4
7.2
33
101
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.8
7.1
138
865
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
9.0
7.1
14
16
M72.0
ICD-10 Finland
Palmar fascial fibromatosis [Dupuytren]
9.0
7.1
14
16
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
4.6
7.0
23
52
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
7.1
7.0
16
23
L01
ICPC
Neck symptom/complaint
2.3
6.9
64
299
M18.1
ICD-10 Finland
Other primary arthrosis of first carpometacarpal joint
14.0
6.9
11
8
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
2.7
6.9
47
187
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.6
6.8
50
207
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
4.2
6.8
24
59
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.0
6.8
88
477
AB5BT
NOMESCO Finland
Blockage of nerv root with X-ray guidance
40.6
6.8
8
*
NDG60
NOMESCO Finland
Arthroplasty of first CMC joint
17.0
6.8
10
6
A06AC01
ATC
ispaghula (psylla seeds); oral
1.9
6.8
117
707
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.7
6.7
224
1645
M71.9
ICD-10 Finland
Bursopathy, unspecified
22.9
6.7
9
*
SPAT1263
SPAT
Sampling
1.7
6.7
202
1444
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.0
6.7
93
520
M01AE01
ATC
ibuprofen; systemic, rectal
1.9
6.6
433
3842
P01BA02
ATC
hydroxychloroquine; oral
2.7
6.6
44
174
AA1AD
NOMESCO Finland
CT of head and brain
1.9
6.6
109
649
J45
ICD-10 Finland
Asthma
2.5
6.5
49
207
X58
ICD-10 Finland
Exposure to other specified factors
2.2
6.5
64
308
G57.6
ICD-10 Finland
Lesion of plantar nerve
5.8
6.5
17
30
ACC51
NOMESCO Finland
Release of median nerve
2.9
6.5
37
132
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.7
6.5
180
1255
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
14.5
6.4
10
7
A02BC02
ATC
pantoprazole; systemic
1.6
6.4
308
2481
NJ3NA
NOMESCO Finland
Measurement of difference in extremity lengty with X-ray
6.1
6.3
16
27
J01MA12
ATC
levofloxacin; systemic
1.9
6.3
95
545
ABD30
NOMESCO Finland
Implantation of spinal stimulation device
18.3
6.3
9
5
ZXC50
NOMESCO Finland
Cryotherapy
4.2
6.3
22
54
C08CA05
ATC
nifedipine; systemic
3.0
6.3
34
119
M47.82
ICD-10 Finland
Other spondylosis, cervical region
4.0
6.3
23
59
M47.9
ICD-10 Finland
Spondylosis, unspecified
4.6
6.2
20
45
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.0
6.2
80
432
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
5.9
6.2
16
28
R06.0
ICD-10 Finland
Dyspnoea
1.8
6.2
109
661
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
2.4
6.2
50
221
R01BA52
ATC
pseudoephedrine, combinations; oral
1.7
6.1
151
1014
M70.2
ICD-10 Finland
Olecranon bursitis
5.3
6.1
17
33
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.3
6.0
54
250
Mortality – FinRegistry
↥Association
Association between endpoint M13_BURSCYSTOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_BURSCYSTOTH | 1.008 [0.85, 1.2] | 0.927 |
| Birth year | 0.991 [0.98, 1.0] | 0.037 |
During the follow-up period (1.1.1998 — 31.12.2019), 165 out of 1495 females with M13_BURSCYSTOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_BURSCYSTOTH | 0.84 [0.69, 1.02] | 0.081 |
| Birth year | 0.988 [0.98, 1.0] | 0.021 |
During the follow-up period (1.1.1998 — 31.12.2019), 131 out of 979 males with M13_BURSCYSTOTH died.
Mortality risk
Mortality risk for people of age
years, who have M13_BURSCYSTOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.077% | 0.169% |
| 5 | 0.515% | 1.033% |
| 10 | 1.341% | 2.501% |
| 15 | 2.446% | 4.822% |
| 20 | 4.036% | 8.41% |
Relationships between endpoints
↥Index endpoint: M13_BURSCYSTOTH – Other bursal cyst
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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