No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
508 |
4. Check minimum number of eventsNone |
508 |
5. Include endpointsNone |
508 |
6. Filter based on genotype QC (FinnGen only) |
508 |
Control definitions (FinnGen only)
- Control exclude
- M13_SOFTTISSUE
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M70
- Name in latin
- Alia bursitis genus
Similar endpoints
↥List of similar endpoints to
Other bursitis of knee
based on the number of shared cases.
Similar with more cases:
- Soft tissue disorders related to use, overuse and pressure
- Soft tissue disorders
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 3713 | 1232 | 2461 |
| Only index persons | 3540 | 1170 | 2370 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.06 | 0.04 | 0.07 |
| Only index persons | 0.07 | 0.04 | 0.09 |
| Median age at first event (years) | |||
| Whole population | 46.67 | 49.87 | 45.16 |
| Only index persons | 46.57 | 49.25 | 45.25 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 508 | 199 | 309 |
| Unadjusted period prevalence (%) | 0.11 | 0.07 | 0.14 |
| Median age at first event (years) | 51.39 | 51.58 | 51.26 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 445
- Matched controls
- 4448
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M70.5
ICD-10 Finland
Other bursitis of knee
3672.0
323.0
382
7
M70.4
ICD-10 Finland
Prepatellar bursitis
35.7
37.5
48
15
7266X
ICD-9 Finland
Peripheral enthesopathies and allied syndromes, Enthesopathy of knee[ENTHESOPATHIA GENUS ALIA DEFINITA SEU NUD]
+∞
32.7
31
*
NGM20
NOMESCO Finland
Excision of synovial ganglion of knee or lower leg
+∞
32.7
31
*
M79.6
ICD-10 Finland
Pain in limb
3.8
31.8
175
655
M25.5
ICD-10 Finland
Pain in joint
3.5
26.9
158
608
J01DB01
ATC
cefalexin; oral
3.8
24.0
392
2936
N02AX02
ATC
tramadol; systemic, rectal
2.8
23.1
213
1091
M03BX02
ATC
tizanidine; oral
2.6
19.7
293
1910
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.6
19.6
226
1281
M01AH05
ATC
etoricoxib; oral
2.4
17.2
272
1768
M75.1
ICD-10 Finland
Rotator cuff syndrome
3.5
16.8
87
292
7266C
ICD-9 Finland
Peripheral enthesopathies and allied syndromes, Enthesopathy of knee[TENDINITIS SEU BURSITIS REGIONIS LIG GENUS COLL LAT]
+∞
16.8
16
*
7266B
ICD-9 Finland
Peripheral enthesopathies and allied syndromes, Enthesopathy of knee[TENDINITIS SEU BURSITIS REGIONIS LIG GENUS COLL MED]
+∞
16.8
16
*
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
10.6
15.7
30
30
M17.1
ICD-10 Finland
Other primary gonarthrosis
2.9
14.1
97
392
M03BC01
ATC
orphenadrine (citrate); systemic
2.6
14.0
120
554
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
3.7
14.0
65
199
M71.0
ICD-10 Finland
Abscess of bursa
55.2
13.9
16
*
M54.5
ICD-10 Finland
Low back pain
2.3
13.5
149
785
M01AB05
ATC
diclofenac; systemic, rectal
2.2
13.4
304
2208
N02BE01
ATC
paracetamol; systemic, rectal
2.6
13.4
380
3080
N02AJ06
ATC
codeine and paracetamol; systemic
2.2
13.2
168
947
M77.0
ICD-10 Finland
Medial epicondylitis
19.8
13.0
19
10
M54.4
ICD-10 Finland
Lumbago with sciatica
3.0
12.9
80
302
N03AX16
ATC
pregabalin; oral
2.6
12.5
102
455
A02BC05
ATC
esomeprazole; systemic
2.2
12.5
179
1057
M13.9
ICD-10 Finland
Arthritis, unspecified
4.5
12.4
44
105
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
4.6
12.2
43
102
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
9.1
12.2
25
29
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
7.1
12.1
29
43
M19.0
ICD-10 Finland
Primary arthrosis of other joints
4.3
12.0
45
114
J01FF01
ATC
clindamycin; systemic
2.3
11.9
140
753
L15
ICPC
Knee symptom/complaint
2.5
11.6
99
452
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
3.8
11.5
49
140
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.1
11.2
152
869
M65.3
ICD-10 Finland
Trigger finger
11.6
11.1
20
18
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
2.9
10.7
66
248
SPAT1153
SPAT
Removal of sutures
2.1
10.7
142
797
M01AC06
ATC
meloxicam; systemic, rectal
2.1
10.5
157
929
M01AX05
ATC
glucosamine; oral
2.6
10.4
80
344
R03AC02
ATC
salbutamol; inhalant
1.9
10.2
218
1474
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.6
10.1
76
322
A02BC02
ATC
pantoprazole; systemic
1.9
10.0
272
2003
WX320
NOMESCO Finland
Spinalanesthesy
2.3
9.9
103
518
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
4.0
9.9
39
104
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.6
9.9
45
136
M70.6
ICD-10 Finland
Trochanteric bursitis
3.7
9.8
42
121
M00.9
ICD-10 Finland
Pyogenic arthritis, unspecified
13.8
9.7
16
12
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
3.0
9.7
57
208
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
56.2
9.7
11
*
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.3
9.7
49
161
L16
ICPC
Ankle symptom/complaint
3.2
9.6
51
174
H02AB06
ATC
prednisolone; systemic
1.9
9.5
193
1270
R07.4
ICD-10 Finland
Chest pain, unspecified
2.1
9.4
116
628
N03AX12
ATC
gabapentin; oral
2.7
9.1
63
254
9473
FHL
Local soft tissue removal or exploration (eg Bursa)
19.1
9.0
13
7
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.0
8.9
127
729
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.8
8.9
218
1524
A46
ICD-10 Finland
Erysipelas
2.5
8.8
73
324
R06.0
ICD-10 Finland
Dyspnoea
2.2
8.8
103
543
M22.4
ICD-10 Finland
Chondromalacia patellae
5.9
8.6
23
41
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.1
8.5
114
636
J01FA06
ATC
roxithromycin; oral
1.9
8.5
167
1077
R06AE07
ATC
cetirizine; oral
1.8
8.4
178
1179
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
3.9
8.2
33
90
R05
ICD-10 Finland
Cough
2.2
8.2
88
445
J01DA01
ATC
[U] cefalexin; systemic
1.8
8.2
262
1975
S18
ICPC
Laceration/cut
1.8
8.1
176
1168
M67.4
ICD-10 Finland
Ganglion
6.5
8.1
20
32
M79.1
ICD-10 Finland
Myalgia
2.9
8.1
48
177
1220
FHL
Arthroscopy
4.7
8.0
26
58
X59
ICD-10 Finland
Exposure to unspecified factor
2.2
7.9
85
429
M01AH01
ATC
celecoxib; oral (coxibs)
2.3
7.8
74
351
ZXA05
NOMESCO Finland
Left side
2.0
7.8
107
598
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.9
7.8
46
169
R51.80
ICD-10 Finland
Headache
2.4
7.7
64
286
M76.9
ICD-10 Finland
Enthesopathy of lower limb, unspecified
25.5
7.6
10
*
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
9.1
7.6
15
17
M01AE02
ATC
naproxen; oral, rectal
1.7
7.6
232
1709
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
4.1
7.5
28
72
J01CA04
ATC
amoxicillin; systemic
1.8
7.4
336
2786
M02AA10
ATC
ketoprofen; topical
2.3
7.4
71
340
M71.1
ICD-10 Finland
Other infective bursitis
+∞
7.3
7
*
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.7
7.3
49
192
M71.9
ICD-10 Finland
Bursopathy, unspecified
16.1
7.3
11
7
R42
ICD-10 Finland
Dizziness and giddiness
2.1
7.3
85
445
M70.2
ICD-10 Finland
Olecranon bursitis
5.2
7.2
21
42
M19.9
ICD-10 Finland
Arthrosis, unspecified
5.5
7.2
20
38
M71.2
ICD-10 Finland
Synovial cyst of popliteal space [Baker]
8.1
7.2
15
19
M02AA07
ATC
piroxicam; topical
1.8
7.1
142
911
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
6.5
7.0
17
27
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.2
7.0
71
350
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
2.9
6.9
40
145
M03BC51
ATC
orphenadrine, combinations; systemic
1.9
6.9
111
660
M79.7
ICD-10 Finland
Fibromyalgia
11.2
6.8
12
11
M70.0
ICD-10 Finland
Chronic crepitant synovitis of hand and wrist
40.7
6.8
8
*
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
5.1
6.7
20
41
1225
FHL
Arthroscopy and other therapeutic procedure
8.0
6.7
14
18
G44.2
ICD-10 Finland
Tension-type headache
2.5
6.6
52
226
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.7
6.6
176
1229
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
14.6
6.4
10
7
S93.4
ICD-10 Finland
Sprain and strain of ankle
2.7
6.4
44
176
J01MA12
ATC
levofloxacin; systemic
2.1
6.4
79
422
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.9
6.3
36
129
L13
ICPC
Hip symptom/complaint
2.3
6.3
58
274
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
18.3
6.3
9
5
NG1DG
NOMESCO Finland
Knee and lower leg very extensive MRI examination with high intensity magnet
+∞
6.3
6
*
M01AB01
ATC
indometacin; systemic, rectal
2.9
6.3
37
137
A02BC03
ATC
lansoprazole; oral
1.8
6.2
116
720
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
2.6
6.2
43
174
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
3.5
6.2
27
81
J45.9
ICD-10 Finland
Asthma, unspecified
2.1
6.1
71
370
S50.0
ICD-10 Finland
Contusion of elbow
6.2
6.0
15
25
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.3
6.0
56
265
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.5
6.0
46
198
Mortality – FinRegistry
↥Association
Association between endpoint M13_BURSITISKNEEOTH and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_BURSITISKNEEOTH | 1.189 [0.9, 1.56] | 0.215 |
| Birth year | 0.992 [0.98, 1.0] | 0.077 |
During the follow-up period (1.1.1998 — 31.12.2019), 79 out of 858 females with M13_BURSITISKNEEOTH died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_BURSITISKNEEOTH | 1.013 [0.83, 1.24] | 0.9 |
| Birth year | 0.986 [0.98, 1.0] | 0.003 |
During the follow-up period (1.1.1998 — 31.12.2019), 145 out of 1693 males with M13_BURSITISKNEEOTH died.
Mortality risk
Mortality risk for people of age
years, who have M13_BURSITISKNEEOTH.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.081% | 0.2% |
| 5 | 0.569% | 1.203% |
| 10 | 1.57% | 2.944% |
| 15 | 2.927% | 5.658% |
| 20 | 5.204% | 9.468% |
Relationships between endpoints
↥Index endpoint: M13_BURSITISKNEEOTH – Other bursitis of knee
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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