Infective bursitis

M13_INFBURSA

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

2 out of 7 registries used, show all original rules.

1068

4. Check minimum number of events

None

1068

5. Include endpoints

None

1068

6. Filter based on genotype QC (FinnGen only)

1068

Control definitions (FinnGen only)

Control exclude
M13_SOFTTISSUE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 8365 2327 6010
Only index persons 7744 2159 5585
Unadjusted period prevalence (%)
Whole population 0.14 0.07 0.17
Only index persons 0.18 0.08 0.21
Median age at first event (years)
Whole population 53.66 58.48 51.73
Only index persons 52.87 57.57 51.05

-FinnGen-

Key figures

All Female Male
Number of individuals 1068 326 742
Unadjusted period prevalence (%) 0.26 0.11 0.33
Median age at first event (years) 55.00 55.51 54.77

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
951
Matched controls
9508
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M71.1
ICD-10 Finland
Other infective bursitis
3613.3
323.0
508
*
M71.0
ICD-10 Finland
Abscess of bursa
5208.2
323.0
468
*
M70.2
ICD-10 Finland
Olecranon bursitis
17.5
88.5
143
95
M75.1
ICD-10 Finland
Rotator cuff syndrome
5.7
86.1
286
665
A46
ICD-10 Finland
Erysipelas
4.9
69.9
265
694
J01FF01
ATC
clindamycin; systemic
3.7
68.3
390
1492
M70.4
ICD-10 Finland
Prepatellar bursitis
25.8
60.5
85
36
J01DB01
ATC
cefalexin; oral
4.2
58.5
841
6121
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
17.5
51.4
82
51
M79.6
ICD-10 Finland
Pain in limb
3.3
51.1
319
1248
N02AX02
ATC
tramadol; systemic, rectal
2.8
46.1
453
2359
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
15.6
42.2
70
48
J01DA01
ATC
[U] cefalexin; systemic
2.6
40.5
634
4172
H02AB06
ATC
prednisolone; systemic
2.5
38.5
480
2766
SPAT1148
SPAT
Treatment of chronic ulcer or burn
3.6
37.2
189
612
N03AX16
ATC
pregabalin; oral
3.0
35.7
242
963
J01CF02
ATC
cloxacillin; systemic
12.9
35.2
63
52
N02BE01
ATC
paracetamol; systemic, rectal
2.9
34.7
819
6452
NBL00
NOMESCO Finland
Suture or reinsertation of rotator cuff of shoulder
7.5
34.2
83
119
S18
ICPC
Laceration/cut
2.3
32.6
431
2489
M71.9
ICD-10 Finland
Bursopathy, unspecified
34.7
31.1
40
12
M19.0
ICD-10 Finland
Primary arthrosis of other joints
4.7
30.3
109
255
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.2
29.5
443
2678
X59
ICD-10 Finland
Exposure to unspecified factor
2.8
28.0
210
877
G56.0
ICD-10 Finland
Carpal tunnel syndrome
3.7
27.9
132
398
NCM20
NOMESCO Finland
Excision of synovial ganglion of elbow or forearm
149.4
27.8
29
*
M25.5
ICD-10 Finland
Pain in joint
2.5
27.5
258
1226
M67.4
ICD-10 Finland
Ganglion
8.5
27.0
60
75
M17.1
ICD-10 Finland
Other primary gonarthrosis
2.6
25.8
214
943
NBG10
NOMESCO Finland
Acromioplastia
22.6
25.8
37
17
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
3.7
25.6
121
364
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
4.7
25.0
88
201
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
3.9
25.0
109
306
N03AX12
ATC
gabapentin; oral
3.1
24.9
149
534
M01AH05
ATC
etoricoxib; oral
2.0
24.7
540
3723
QDA10
NOMESCO Finland
Incision of skin of lower limb
22.7
24.5
35
16
N02AJ06
ATC
codeine and paracetamol; systemic
2.2
24.4
350
2021
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
3.4
23.9
127
418
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
3.2
23.7
134
461
ZXD05
NOMESCO Finland
Urgent procedure
2.2
23.2
310
1727
M79.0
ICD-10 Finland
Rheumatism, unspecified
37.3
23.1
29
8
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
3.8
23.1
102
289
M54.5
ICD-10 Finland
Low back pain
2.2
22.7
283
1524
L02.4
ICD-10 Finland
Cutaneous abscess, furuncle and carbuncle of limb
5.8
21.8
63
115
M00.9
ICD-10 Finland
Pyogenic arthritis, unspecified
12.3
21.7
39
33
M13.9
ICD-10 Finland
Arthritis, unspecified
3.9
21.0
89
243
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
3.6
21.0
98
291
M54.4
ICD-10 Finland
Lumbago with sciatica
2.7
20.9
154
629
SPAT1255
SPAT
Intravenous administration of medicine
4.0
20.9
87
234
A02BC02
ATC
pantoprazole; systemic
1.9
20.8
585
4311
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
4.4
20.7
77
186
NDM40
NOMESCO Finland
Discission of sheath of tendon of wrist or hand
214.5
20.7
21
*
M03BC01
ATC
orphenadrine (citrate); systemic
2.3
20.5
215
1059
NBA30
NOMESCO Finland
Exploration of joint of shoulder or upper arm, arthroscopic
12.9
20.5
36
29
QCA10
NOMESCO Finland
Incision of skin of upper limb
27.7
20.1
27
10
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
3.5
19.9
96
292
X58
ICD-10 Finland
Exposure to other specified factors
2.7
19.8
143
575
M01AB05
ATC
diclofenac; systemic, rectal
1.9
19.7
611
4613
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
7.2
19.7
48
70
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.7
19.5
145
594
SPAT1153
SPAT
Removal of sutures
2.0
19.4
304
1784
NBF25
NOMESCO Finland
Operation for humeroscapular osteochondritis, arthroscopic
14.4
19.2
32
23
R06.0
ICD-10 Finland
Dyspnoea
2.2
19.1
224
1161
L10
ICPC
Elbow symptom/complaint
4.8
19.0
65
144
M01AE02
ATC
naproxen; oral, rectal
1.9
19.0
492
3470
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.7
18.6
137
556
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
3.0
18.6
116
426
M01AH01
ATC
celecoxib; oral (coxibs)
2.4
18.5
169
773
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
5.0
18.4
60
127
A02BC05
ATC
esomeprazole; systemic
1.9
18.3
361
2303
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
4.3
18.1
69
171
M10.9
ICD-10 Finland
Gout, unspecified
3.5
17.9
87
266
M01AE03
ATC
ketoprofen; systemic, rectal
1.9
17.9
349
2212
M70.6
ICD-10 Finland
Trochanteric bursitis
3.5
17.9
87
267
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
2.7
17.8
132
539
J01MA12
ATC
levofloxacin; systemic
2.3
17.6
192
957
A02BC03
ATC
lansoprazole; oral
2.0
17.5
263
1505
J01CF05
ATC
flucloxacillin; systemic
4.7
17.5
60
134
M02AA07
ATC
piroxicam; topical
1.9
17.4
317
1957
M01AC06
ATC
meloxicam; systemic, rectal
1.9
17.4
321
1987
J45.9
ICD-10 Finland
Asthma, unspecified
2.4
17.4
160
735
M48.0
ICD-10 Finland
Spinal stenosis
2.9
17.2
113
428
L12
ICPC
Hand/finger symptom/complaint
2.7
17.2
125
501
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.0
17.2
256
1460
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.0
17.2
282
1673
J01AA02
ATC
doxycycline; systemic
1.9
17.1
712
5798
M65.3
ICD-10 Finland
Trigger finger
9.3
17.0
35
39
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
17.0
406
2751
SPAT1263
SPAT
Sampling
1.9
17.0
372
2446
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
5.7
17.0
49
90
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.4
16.9
85
268
M03BX02
ATC
tizanidine; oral
1.8
16.8
549
4110
R03AC02
ATC
salbutamol; inhalant
1.8
16.8
444
3106
ZXA05
NOMESCO Finland
Left side
2.1
16.7
234
1302
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
4.0
16.5
67
176
S97
ICPC
Chronic ulcer skin
3.8
16.5
71
197
A02BA02
ATC
ranitidine; systemic
2.2
16.4
187
951
N06AA09
ATC
amitriptyline; systemic
3.2
16.3
91
306
NC1AA
NOMESCO Finland
Elbow X-ray examination without contrast
5.8
16.3
46
82
L15
ICPC
Knee symptom/complaint
2.2
16.3
186
944
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.9
16.3
102
374
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
5.5
15.9
47
89
NBT60
NOMESCO Finland
Forcible manipulation of humeroscapular joint
26.8
15.6
21
8
M79.7
ICD-10 Finland
Fibromyalgia
12.0
15.6
28
24
NF1AA
NOMESCO Finland
Hip X-ray examination
3.2
15.6
85
284
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
3.5
15.5
75
229
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
3.7
15.4
68
193
QCB05
NOMESCO Finland
Revision of wound of skin of upper limb
11.5
15.3
28
25
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.0
15.3
237
1364
NBL22
NOMESCO Finland
Myotomy, tenotomy or excision of tendon of upper arm
20.4
15.1
22
11
M01AH02
ATC
rofecoxib; oral
2.6
15.1
120
508
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.2
15.1
80
262
TPH04
NOMESCO Finland
Cathetrisation of vein
2.1
15.1
204
1111
ZXA00
NOMESCO Finland
Right side
2.0
15.0
243
1422
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
8.9
14.8
31
36
M70.3
ICD-10 Finland
Other bursitis of elbow
18.7
14.7
22
12
C03CA01
ATC
furosemide; systemic
1.9
14.6
248
1475
ZXE10
NOMESCO Finland
More than one and less than three hours
1.8
14.5
317
2056
L08
ICPC
Shoulder symptom/complaint
2.2
14.5
159
790
P01BA02
ATC
hydroxychloroquine; oral
3.1
14.4
81
276
H02AB04
ATC
methylprednisolone; systemic
2.4
14.0
131
603
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.9
13.9
260
1593
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
13.8
231
1360
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
2.4
13.8
118
520
N06AX21
ATC
duloxetine; oral
2.8
13.6
89
336
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
1.9
13.6
248
1507
QCB10
NOMESCO Finland
Major dressing of wound of skin of upper limb
5.8
13.6
38
68
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.8
13.5
92
356
M01AX17
ATC
nimesulide; oral
2.0
13.5
209
1195
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
3.6
13.5
62
182
NG1DA
NOMESCO Finland
X-ray of knees
7.9
13.4
30
39
Y88.3
ICD-10 Finland
Sequelae of surgical and medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
5.7
13.4
38
69
M79.1
ICD-10 Finland
Myalgia
2.8
13.4
87
328
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
2.6
13.4
98
397
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.7
13.3
351
2404
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
2.7
13.2
92
360
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
3.1
13.0
73
248
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.2
12.9
142
704
R51.80
ICD-10 Finland
Headache
2.4
12.9
112
497
L17
ICPC
Foot/toe symptom/complaint
1.9
12.9
206
1193
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.7
12.8
423
3080
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.9
12.8
236
1437
L87
ICPC
Bursitis/tendinitis/synovitis NOS
7.6
12.7
29
39
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.7
12.7
370
2599
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.1
12.6
147
750
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.9
12.4
214
1270
L88
ICPC
Rheumatoid/seropositive arthritis
4.3
12.4
45
108
NDM20
NOMESCO Finland
Excision of synovial ganglion of wrist or hand
38.1
12.2
15
*
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
3.0
12.2
71
249
M01AX05
ATC
glucosamine; oral
2.0
12.2
160
857
G56.2
ICD-10 Finland
Lesion of ulnar nerve
4.9
12.2
39
82
WX204
NOMESCO Finland
Axillary plexus blockaced
5.5
12.2
35
65
J01MA02
ATC
ciprofloxacin; systemic
1.7
12.0
341
2362
M04AA01
ATC
allopurinol; systemic
2.1
12.0
139
706
N05CF01
ATC
zopiclone; oral
1.8
12.0
276
1799
M75.9
ICD-10 Finland
Shoulder lesion, unspecified
4.4
12.0
43
102
N02AA05
ATC
oxycodone; systemic
2.2
11.9
129
634
NAG40
NOMESCO Finland
Anterior fusion of cervical spine without fixation
6.6
11.9
30
47
R06AE07
ATC
cetirizine; oral
1.7
11.9
337
2334
M10.0
ICD-10 Finland
Idiopathic gout
4.4
11.8
42
99
NDM10
NOMESCO Finland
Palmar fasciotomy of hand
30.4
11.7
15
5
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
4.5
11.6
40
91
R01AD09
ATC
mometasone; nasal
1.7
11.5
349
2458
W19
ICD-10 Finland
Unspecified fall
2.6
11.5
87
359
M71.2
ICD-10 Finland
Synovial cyst of popliteal space [Baker]
6.8
11.5
28
42
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
4.9
11.4
36
75
Z01.8
ICD-10 Finland
Other specified special examinations
1.9
11.4
182
1047
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.8
11.3
255
1645
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
3.1
11.3
62
209
SPAT1229
SPAT
Assessment of need for aid
2.7
11.2
75
288
SPAT1301
SPAT
No procedures
1.7
11.2
268
1760
Z3226
NOMESCO Finland
Physiotherapist
2.0
11.2
162
900
TQW40
NOMESCO Finland
Remowal of suture of skin
2.8
11.2
74
282
NHM20
NOMESCO Finland
Excision of synovial ganglion of ankle or foot
20.3
11.2
16
8
M72.0
ICD-10 Finland
Palmar fascial fibromatosis [Dupuytren]
10.2
11.0
21
21
G47.3
ICD-10 Finland
Sleep apnoea
1.8
10.9
213
1313
WX320
NOMESCO Finland
Spinalanesthesy
1.8
10.9
197
1184
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.1
10.9
125
632
WX408
NOMESCO Finland
General anesthesy, balanced
1.8
10.9
235
1494
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.0
10.9
143
765
L03
ICPC
Low back symptom/complaint
1.9
10.9
180
1049
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.0
10.8
150
819
R42
ICD-10 Finland
Dizziness and giddiness
1.9
10.8
169
962
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
2.8
10.8
69
258
NGS99
NOMESCO Finland
Other operation for infection of tendon, joint or bone of knee or lower leg
28.4
10.7
14
5
QWC00
NOMESCO Finland
Reoperation for superficial infection in surgery of skin
21.7
10.7
15
7
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
2.6
10.7
78
315
SPAT1202
SPAT
Intra-articular injection
4.4
10.7
38
90
S06
ICPC
Rash localized
3.1
10.6
57
190
M47.9
ICD-10 Finland
Spondylosis, unspecified
4.7
10.6
35
77
WX110
NOMESCO Finland
Local anesthesy
1.6
10.5
585
4775
M70.5
ICD-10 Finland
Other bursitis of knee
9.3
10.5
21
23
A07EC01
ATC
sulfasalazine; oral, rectal
2.6
10.5
77
312
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.9
10.5
42
111
A49.9
ICD-10 Finland
Bacterial infection, unspecified
2.2
10.5
106
506
J04AB02
ATC
rifampicin; systemic
7.8
10.4
23
30
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.9
10.4
64
232
B01AB05
ATC
enoxaparin; parenteral
1.7
10.4
251
1651
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.0
10.2
138
746
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
3.7
10.2
43
119
J01CE02
ATC
phenoxymethylpenicillin; oral
1.6
10.2
598
4931
NB1BG
NOMESCO Finland
Shoulder and humerus MRI examination with high intensity magnet
8.0
10.1
22
28
M75.5
ICD-10 Finland
Bursitis of shoulder
7.0
10.1
24
35
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
3.8
10.1
41
110
R60.0
ICD-10 Finland
Localized oedema
2.3
10.1
92
419
M01AE01
ATC
ibuprofen; systemic, rectal
1.8
10.0
802
7157
ACC51
NOMESCO Finland
Release of median nerve
3.0
10.0
58
203
R50.9
ICD-10 Finland
Fever, unspecified
2.1
10.0
120
615
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
3.8
10.0
41
111
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
4.0
10.0
39
101
J01FA06
ATC
roxithromycin; oral
1.6
9.9
321
2282
M54.9
ICD-10 Finland
Dorsalgia, unspecified
2.4
9.8
85
377
M01AB01
ATC
indometacin; systemic, rectal
2.4
9.8
84
370
NH3EA
NOMESCO Finland
Feet X-ray examination with load
6.2
9.7
25
41
L03.9
ICD-10 Finland
Cellulitis, unspecified
5.6
9.7
27
49
A02BC01
ATC
omeprazole; systemic
1.7
9.7
223
1440
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
2.1
9.6
114
584
M54.1
ICD-10 Finland
Radiculopathy
4.1
9.6
36
90
M77.1
ICD-10 Finland
Lateral epicondylitis
3.2
9.5
49
159
NHG80
NOMESCO Finland
Fusion of first tarsometatarsal joint
4.6
9.5
32
72
M54.2
ICD-10 Finland
Cervicalgia
3.0
9.5
54
186
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
3.6
9.5
42
122
H02BX01
ATC
methylprednisolone, combinations; systemic
3.3
9.3
46
145
NB1CG
NOMESCO Finland
Shoulder and humerus extensive MRI examination with high intensity magnet
8.8
9.3
19
22
SAA03
NOMESCO Finland
Extended examination of mouth
1.6
9.2
304
2161
S80.0
ICD-10 Finland
Contusion of knee
3.0
9.2
53
186
C07AB07
ATC
bisoprolol; oral
1.5
9.1
402
3062
D07AA02
ATC
hydrocortisone; topical
2.0
9.1
114
596
NHQ40
NOMESCO Finland
Amputation of toe
6.3
9.1
23
37
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
6.0
9.1
24
41
L11
ICPC
Wrist symptom/complaint
2.7
9.1
61
235
R01BA52
ATC
pseudoephedrine, combinations; oral
1.7
9.1
243
1637
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.5
9.1
434
3368
B01AF01
ATC
rivaroxaban; oral
2.1
9.1
107
545
SPAT1310
SPAT
Counselling related to known health issue
1.6
9.1
263
1807
L99
ICPC
Musculoskeletal disease other
7.1
9.1
21
30
T84.5
ICD-10 Finland
Infection and inflammatory reaction due to internal joint prosthesis
7.1
9.1
21
30
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
4.3
9.1
32
76
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
1.9
9.0
148
855
SPAT1211
SPAT
Application of soft bandage
2.4
9.0
79
352
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
9.0
575
4764
A06AC01
ATC
ispaghula (psylla seeds); oral
1.8
8.9
180
1116
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.3
8.9
81
369
NH1CG
NOMESCO Finland
Ankle and foot extensive MRI examination with high intensity magnet
10.8
8.8
16
15
-34
ICPC
Blood test
3.9
8.8
35
93
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.0
8.7
117
628
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
1.8
8.7
154
913
N05BA01
ATC
diazepam; systemic, rectal
2.0
8.7
113
601
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
2.0
8.7
113
602
M16.1
ICD-10 Finland
Other primary coxarthrosis
2.2
8.7
92
450
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.5
8.6
68
287
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
4.5
8.6
29
66
R02
ICPC
Shortness of breath/dyspnoea
2.1
8.6
93
458
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
3.3
8.6
41
127
L16
ICPC
Ankle symptom/complaint
2.3
8.5
76
341
J01CA04
ATC
amoxicillin; systemic
1.5
8.5
672
5797
NDL52
NOMESCO Finland
Tenosynovectomy of hand
20.2
8.5
12
6
NH3FA
NOMESCO Finland
Weight-bearing X-ray of foot
7.4
8.5
19
26
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
4.8
8.5
27
58
NCS99
NOMESCO Finland
Other operation for infection of tendon, joint or bone of elbow or forearm
90.8
8.4
9
*
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.5
8.4
385
2945
S06.0
ICD-10 Finland
Concussion
2.2
8.4
85
405
M16.9
ICD-10 Finland
Coxarthrosis, unspecified
3.2
8.4
43
140
A01
ICPC
Pain general/multiple sites
2.6
8.4
58
229
ACC53
NOMESCO Finland
Release of ulnar nerve
8.0
8.4
18
23
P01AB01
ATC
metronidazole; oral, rectal
1.6
8.4
294
2113
R05
ICPC
Cough
1.8
8.4
161
980
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
8.4
300
2166
NFM20
NOMESCO Finland
Excision of bursa of hip or thigh
+∞
8.3
8
*
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
4.7
8.3
27
59
S51.0
ICD-10 Finland
Open wound of elbow
6.3
8.3
21
34
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
8.6
8.3
17
20
J01CF01
ATC
dicloxacillin; systemic
8.6
8.3
17
20
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.5
8.3
450
3565
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
1.7
8.3
184
1172
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
3.8
8.3
33
88
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
8.3
500
4058
NB1AD
NOMESCO Finland
Shoulder CT examination
7.2
8.3
19
27
N06AX11
ATC
mirtazapine; oral
1.6
8.3
243
1670
NHG77
NOMESCO Finland
Arthroplasty of interphalangeal tarsal joint(s)
5.5
8.2
23
43
SPAT1312
SPAT
General health counselling
1.6
8.1
251
1745
NGM20
NOMESCO Finland
Excision of synovial ganglion of knee or lower leg
33.6
8.1
10
*
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
5.1
8.1
24
48
SPAT1262
SPAT
Handing over of treatment supplies
1.7
8.0
166
1033
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
7.3
8.0
18
25
L01
ICPC
Neck symptom/complaint
2.1
8.0
95
487
SPAT1249
SPAT
Treatment-related counselling outside office
1.5
7.9
313
2306
M01AC02
ATC
tenoxicam; systemic, rectal
3.0
7.9
45
156
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.6
7.9
210
1404
S43.4
ICD-10 Finland
Sprain and strain of shoulder joint
3.6
7.8
33
93
212
Kela drug reimbursment
Gout
3.9
7.8
30
78
R4120
NOMESCO Finland
Occupational therapy
2.7
7.8
53
206
L04AX01
ATC
azathioprine; systemic
2.9
7.8
45
159
D07AC13
ATC
mometasone; topical
1.6
7.8
238
1651
NGB40
NOMESCO Finland
Primary total prosthetic replacement of knee joint with patellar part - sliding prosthesis
4.3
7.7
27
64
N06AA10
ATC
nortriptyline; systemic
5.6
7.7
21
38
GD1AD
NOMESCO Finland
Thorax CT examination
2.8
7.7
46
167
M01AC01
ATC
piroxicam; systemic, rectal
1.9
7.7
113
630
M19.2
ICD-10 Finland
Other secondary arthrosis
8.1
7.6
16
20
NFH30
NOMESCO Finland
Reduction of dislocation prosthesis of hip joint, closed
12.0
7.6
13
11
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.3
7.6
72
333
TQW11
NOMESCO Finland
Vacuum treatment of wound
4.2
7.5
27
66
AA1AD
NOMESCO Finland
CT of head and brain
1.6
7.5
194
1284
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.1
7.5
84
421
NHG76
NOMESCO Finland
Arthroplasty of other tarsometatarsal joint
7.2
7.5
17
24
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.5
7.5
465
3766
K02.1
ICD-10 Finland
Caries of dentine
1.5
7.4
454
3660
QX3HE
NOMESCO Finland
Ultrsound examination of lesion close to skin
6.5
7.4
18
28
M19.8
ICD-10 Finland
Other specified arthrosis
3.9
7.4
29
77
SFA00
NOMESCO Finland
Small filling
1.9
7.4
105
579
M77.4
ICD-10 Finland
Metatarsalgia
3.2
7.4
37
120
L04AA01
ATC
[U] ciclosporin; systemic
4.8
7.4
23
49
M54.6
ICD-10 Finland
Pain in thoracic spine
2.6
7.3
51
202
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
1.8
7.3
136
819
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.5
7.3
257
1836
M43.1
ICD-10 Finland
Spondylolisthesis
3.4
7.3
34
104
M66.4
ICD-10 Finland
Spontaneous rupture of other tendons
+∞
7.3
7
*
WX202
NOMESCO Finland
Supraclavicular plexus blockade
6.3
7.3
18
29
SPAT1216
SPAT
Assessment of functional ability
1.8
7.3
118
678
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.8
7.2
133
796
L28
ICPC
Limited function/disability (L)
1.8
7.2
116
665
TNH11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in ankle joint or foot joint
7.4
7.2
16
22
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
2.5
7.2
53
216
M05BA04
ATC
alendronic acid; oral
2.5
7.2
56
235
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
2.3
7.2
65
297
R4110
NOMESCO Finland
Physiotherapy
1.6
7.2
210
1436
M70.0
ICD-10 Finland
Chronic crepitant synovitis of hand and wrist
30.2
7.2
9
*
L70
ICPC
Infection of musculoskeletal system
20.2
7.1
10
5
C08CA01
ATC
amlodipine; oral
1.5
7.1
304
2271
L04AA13
ATC
leflunomide; oral
3.6
7.1
30
85
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
3.6
7.1
30
85
M79.5
ICD-10 Finland
Residual foreign body in soft tissue
6.1
7.1
18
30
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.2
7.1
69
325
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
3.1
7.1
37
124
R01AD08
ATC
fluticasone; nasal
1.6
7.0
209
1436
L13
ICPC
Hip symptom/complaint
1.9
7.0
102
565
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
2.2
7.0
69
327
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.5
7.0
284
2096
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
3.4
7.0
32
97
N05BA04
ATC
oxazepam; oral
1.6
7.0
186
1242
SAA02
NOMESCO Finland
Basic examination of mouth
1.4
7.0
502
4160
NE1AA
NOMESCO Finland
Pelvis X-ray examination
2.4
7.0
56
242
GD1CD
NOMESCO Finland
Thorax extensive CT-examination
6.4
7.0
17
27
C01DA14
ATC
isosorbide mononitrate; oral
1.8
6.9
114
660
-43
ICPC
Other diagnostic procedure
5.5
6.9
19
35
E0000UV
ATC
NA
1.5
6.9
299
2234
M02AA10
ATC
ketoprofen; topical
1.8
6.9
117
682
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
2.8
6.9
41
149
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
4.9
6.9
21
44
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.6
6.9
186
1246
M76.0
ICD-10 Finland
Gluteal tendinitis
8.3
6.8
14
17
M76.6
ICD-10 Finland
Achilles tendinitis
3.6
6.8
29
83
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
2.3
6.8
62
282
NBG00
NOMESCO Finland
Plastic operation on acromioclavicular joint
9.4
6.8
13
14
M20.4
ICD-10 Finland
Other hammer toe(s) (acquired)
3.2
6.8
33
105
W10
ICD-10 Finland
Fall on and from stairs and steps
2.8
6.8
41
151
SPAT1254
SPAT
Administration of medicine
1.8
6.7
107
613
-48
ICPC
Clarification/discussion RFE/demand
4.1
6.7
24
59
XF402
NOMESCO Finland
ECG with work load test
1.9
6.7
98
546
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.7
6.7
130
791
NDF60
NOMESCO Finland
Operation for osteochondritis of a joint of hand,v
22.7
6.7
9
*
J01MA14
ATC
moxifloxacin; systemic
2.0
6.7
82
428
C09AA02
ATC
enalapril; systemic
1.6
6.7
167
1097
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.8
6.7
41
153
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.6
6.7
47
189
7227C
ICD-9 Finland
Intervertebral disk disorders, Intervertebral disk disorder with myelopathy[SYNDROMA ISCHIADICUM]
3.5
6.7
29
85
M65.8
ICD-10 Finland
Other synovitis and tenosynovitis
6.5
6.7
16
25
Z3231
NOMESCO Finland
Registered nurse
1.5
6.6
221
1558
K07.60
ICD-10 Finland
Snapping jaw
3.3
6.6
31
96
WX200
NOMESCO Finland
Interscalenous plexus blockade
5.9
6.6
17
29
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
2.6
6.5
44
173
L86
ICPC
Back syndrome with radiating pain
2.7
6.5
42
159
WX213
NOMESCO Finland
Lower leg blockade
6.9
6.5
15
22
NK1XE
NOMESCO Finland
Other ultrasound examinnation of muscle or tendon
6.9
6.5
15
22
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.8
6.5
107
620
ND2BA
NOMESCO Finland
Hand and fingers extensive X-ray examination
3.9
6.5
25
66
X50
ICD-10 Finland
Overexertion and strenuous or repetitive movements
3.9
6.5
25
66
C10AX09
ATC
ezetimibe; oral
1.9
6.5
99
558
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.6
6.4
193
1324
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
4.3
6.4
22
52
D07AC01
ATC
betamethasone; topical
1.5
6.4
275
2046
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
3.1
6.4
32
104
M79.9
ICD-10 Finland
Soft tissue disorder, unspecified
14.4
6.4
10
7
A06AD11
ATC
lactulose; oral
1.8
6.4
106
616
J44.1
ICD-10 Finland
Chronic obstructive pulmonary disease with acute exacerbation, unspecified
3.2
6.4
31
99
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
2.4
6.4
49
207
R03AK07
ATC
formoterol and budesonide; inhalant
1.7
6.4
146
936
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
6.6
6.3
15
23
R03BA05
ATC
fluticasone; inhalant
1.7
6.3
132
823
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
3.5
6.3
27
78
-50
ICPC
Medication/prescr/renewal
2.9
6.3
37
133
A41.0
ICD-10 Finland
Sepsis due to Staphylococcus aureus
3.6
6.3
26
73
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.3
6.3
57
261
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
2.1
6.3
68
334
N05CD07
ATC
temazepam; oral
1.8
6.3
100
573
WZA90
NOMESCO Finland
Other doctors statement
1.6
6.3
176
1187
WX704
NOMESCO Finland
Intubation
2.2
6.3
61
288
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
3.0
6.3
33
112
NHM10
NOMESCO Finland
Fasciotomy of ankle or foot
+∞
6.3
6
*
7261X
ICD-9 Finland
Peripheral enthesopathies and allied syndromes, Rotator cuff syndrome of shoulder and allied disorders[MUU TAI TARKEMMIN MÄÄRITTELEM KIERTÄJÄKALVOSINSDR]
+∞
6.3
6
*
7263A
ICD-9 Finland
Peripheral enthesopathies and allied syndromes, Enthesopathy of elbow region[EPICONDYLITIS LATERALIS HUMERI]
+∞
6.3
6
*
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.4
6.2
350
2745
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.6
6.2
191
1319
NB1CM
NOMESCO Finland
Shoulder and humerus extensive MRI examination with 3 Tesla magnet
26.9
6.2
8
*
M35.0
ICD-10 Finland
Sicca syndrome [Sjögren]
5.1
6.2
18
36
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.0
6.2
80
424
N05AH04
ATC
quetiapine; oral
1.7
6.2
124
762
J01FA10
ATC
azithromycin; systemic
1.4
6.2
436
3567
TND11
NOMESCO Finland
Injection of diagnostic or therapeutic substance in joint, wrist or hand
4.5
6.2
20
45
S76
ICPC
Skin infection other
2.5
6.2
44
178
E66.01
ICD-10 Finland
Obesity due to excess calories
2.3
6.2
56
257
D07AD01
ATC
clobetasol; topical
1.7
6.2
124
765
L03.0
ICD-10 Finland
Cellulitis of finger and toe
2.2
6.2
58
270
M01AB08
ATC
etodolac; oral
2.3
6.1
55
249
U07.1
ICD-10 Finland
Emergency use of U07.1 | COVID-19, virus identified
1.7
6.1
117
708
J01DA06
ATC
[U] cefuroxime; systemic
1.7
6.1
114
687
J46
ICD-10 Finland
Status asthmaticus
3.5
6.1
26
75
ZXE20
NOMESCO Finland
More than three and less than five hours
1.7
6.1
117
709
A41.9
ICD-10 Finland
Sepsis, unspecified
2.8
6.1
37
137
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.3
6.1
55
250
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
1.5
6.1
219
1566
R07.3
ICD-10 Finland
Other chest pain
2.1
6.1
69
347
ABC56
NOMESCO Finland
Decompression of lumbar spinal canal and nerve roots
3.9
6.1
23
60
TNX32
NOMESCO Finland
Custom moulded splint, unspecified region
2.5
6.1
44
180
WX002
NOMESCO Finland
Sedation and analgesia
1.6
6.1
157
1038
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.4
6.1
49
210
M01AE52
ATC
naproxen and esomeprazole; oral
3.4
6.1
27
81
WX702
NOMESCO Finland
Supraglottic ventilation device
2.5
6.1
46
191
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
6.7
6.0
14
21
M20.1
ICD-10 Finland
Hallux valgus (acquired)
2.2
6.0
57
265
NDM99
NOMESCO Finland
Other operation on fascia, ganglion, synovial sheath or bursa of wrist or hand
10.1
6.0
11
11
M96.1
ICD-10 Finland
Postlaminectomy syndrome, not elsewhere classified
10.1
6.0
11
11
NGF20
NOMESCO Finland
Operation for osteochondritis of knee, open
10.1
6.0
11
11
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
3.1
6.0
30
98
J45.1
ICD-10 Finland
Nonallergic asthma
2.3
6.0
52
233
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
4.0
6.0
22
56
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
6.1
6.0
15
25

Mortality – FinRegistry

Association

Association between endpoint M13_INFBURSA and mortality.

Females

Parameter HR [95% CI] p-value
M13_INFBURSA 1.424 [1.23, 1.65] < 0.001
Birth year 0.993 [0.98, 1.0] 0.085

During the follow-up period (1.1.1998 — 31.12.2019), 501 out of 2040 females with M13_INFBURSA died.

Males

Parameter HR [95% CI] p-value
M13_INFBURSA 1.548 [1.38, 1.73] < 0.001
Birth year 0.99 [0.98, 1.0] 0.029

During the follow-up period (1.1.1998 — 31.12.2019), 1088 out of 5234 males with M13_INFBURSA died.

Mortality risk

Mortality risk for people of age

years, who have M13_INFBURSA.

N-year risk Females Males
1 0.138% 0.342%
5 0.763% 2.043%
10 1.942% 4.868%
15 3.474% 9.815%
20 6.294% 15.977%

Relationships between endpoints

Index endpoint: M13_INFBURSA – Infective bursitis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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