No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
696 |
4. Check minimum number of eventsNone |
696 |
5. Include endpointsNone |
696 |
6. Filter based on genotype QC (FinnGen only) |
696 |
Control definitions (FinnGen only)
- Control exclude
- M13_DORSOPATHY
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M76
- Name in latin
- Tendinitis ligamenti patellae
Similar endpoints
↥List of similar endpoints to
Patellar tendinitis
based on the number of shared cases.
Similar with more cases:
- Enthesopathies of lower limb, excluding foot
- Dorsopathies
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 6071 | 2095 | 3956 |
| Only index persons | 5910 | 2037 | 3873 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.09 | 0.06 | 0.11 |
| Only index persons | 0.12 | 0.07 | 0.15 |
| Median age at first event (years) | |||
| Whole population | 28.21 | 26.44 | 29.13 |
| Only index persons | 28.42 | 26.77 | 29.29 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 696 | 301 | 395 |
| Unadjusted period prevalence (%) | 0.14 | 0.10 | 0.17 |
| Median age at first event (years) | 34.93 | 32.82 | 36.55 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 608
- Matched controls
- 6078
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M76.5
ICD-10 Finland
Patellar tendinitis
4062.9
323.0
562
18
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
29.6
57.7
78
30
M25.5
ICD-10 Finland
Pain in joint
4.5
56.6
254
828
7266D
ICD-9 Finland
Peripheral enthesopathies and allied syndromes, Enthesopathy of knee[TENDINITIS SEU APICITIS PATELLAE]
+∞
51.8
49
*
M01AH05
ATC
etoricoxib; oral
3.6
49.2
409
2189
NGL30
NOMESCO Finland
Plastic repair or reinsertation of tendon of patella
236.6
43.5
44
*
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
6.7
41.3
113
200
M54.4
ICD-10 Finland
Lumbago with sciatica
6.8
38.9
104
178
M22.4
ICD-10 Finland
Chondromalacia patellae
11.2
36.6
71
71
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
30.2
33.8
45
16
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
8.8
33.5
74
94
M54.5
ICD-10 Finland
Low back pain
3.3
32.9
206
814
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
8.4
32.9
75
100
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
15.6
32.1
53
37
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
2.8
30.9
295
1530
N02AX02
ATC
tramadol; systemic, rectal
3.0
30.8
231
1027
M01AB05
ATC
diclofenac; systemic, rectal
2.7
28.8
417
2720
NGL58
NOMESCO Finland
Tenolysis or tenosynovectomy of knee or lower leg
+∞
28.3
27
*
M01AC06
ATC
meloxicam; systemic, rectal
2.9
27.7
215
964
M79.6
ICD-10 Finland
Pain in limb
2.8
26.9
218
1002
N03AX16
ATC
pregabalin; oral
3.8
26.5
127
399
L15
ICPC
Knee symptom/complaint
3.4
26.2
150
541
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
4.3
23.9
94
246
M03BX02
ATC
tizanidine; oral
2.4
22.5
374
2458
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
65.0
22.0
25
*
M48.0
ICD-10 Finland
Spinal stenosis
83.2
21.8
24
*
M54.9
ICD-10 Finland
Dorsalgia, unspecified
5.4
21.6
67
136
N02AJ06
ATC
codeine and paracetamol; systemic
2.4
20.7
232
1237
M01AE02
ATC
naproxen; oral, rectal
2.2
20.4
361
2394
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
5.1
19.7
64
137
M76.6
ICD-10 Finland
Achilles tendinitis
8.0
19.2
44
59
M17.1
ICD-10 Finland
Other primary gonarthrosis
3.5
18.5
94
305
H02AB06
ATC
prednisolone; systemic
2.2
18.4
252
1461
N03AX12
ATC
gabapentin; oral
4.1
18.2
74
198
M03BC01
ATC
orphenadrine (citrate); systemic
2.6
18.2
152
682
NGF00
NOMESCO Finland
Excision of plica of synovy of knee
8.3
18.1
40
51
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
68.7
17.8
20
*
M23.8
ICD-10 Finland
Other internal derangements of knee
5.8
17.2
49
90
L03
ICPC
Low back symptom/complaint
2.7
16.9
129
548
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
7.1
16.3
40
60
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.5
16.2
143
657
NGL99
NOMESCO Finland
Other operation on muscle or tendon of knee or lower leg
164.0
15.5
16
*
M76.8
ICD-10 Finland
Other enthesopathies of lower limb, excluding foot
13.7
14.8
25
19
NG1CG
NOMESCO Finland
Knee and lower leg extensive MRI examination with high intensity magnet
7.6
14.7
34
47
N02BE01
ATC
paracetamol; systemic, rectal
2.1
14.7
474
3781
J01AA02
ATC
doxycycline; systemic
2.0
14.6
420
3190
X59
ICD-10 Finland
Exposure to unspecified factor
2.4
14.4
137
651
M54.2
ICD-10 Finland
Cervicalgia
5.7
14.3
41
76
M01AE01
ATC
ibuprofen; systemic, rectal
2.7
13.7
554
4805
R03AC02
ATC
salbutamol; inhalant
1.9
13.6
298
2020
M02AA07
ATC
piroxicam; topical
2.2
13.5
169
914
M01AH01
ATC
celecoxib; oral (coxibs)
2.9
13.3
87
333
A02BC02
ATC
pantoprazole; systemic
1.9
13.2
315
2192
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
15.5
13.2
21
14
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.4
12.9
115
529
S83.6
ICD-10 Finland
Sprain and strain of other and unspecified parts of knee
3.9
12.6
52
142
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
2.3
12.5
134
673
M02AA10
ATC
ketoprofen; topical
2.7
12.4
90
368
M43.1
ICD-10 Finland
Spondylolisthesis
21.8
12.1
17
8
M43.0
ICD-10 Finland
Spondylolysis
+∞
11.5
11
*
NGM99
NOMESCO Finland
Other operation on fascia, ganglion, or bursa of knee or lower leg
+∞
11.5
11
*
M54.3
ICD-10 Finland
Sciatica
8.6
11.4
24
29
ZXA00
NOMESCO Finland
Right side
2.3
11.3
118
582
R52.9
ICD-10 Finland
Pain, unspecified
3.4
11.3
54
167
M01AE03
ATC
ketoprofen; systemic, rectal
2.0
11.2
184
1099
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
2.7
11.2
77
306
M01AX17
ATC
nimesulide; oral
2.4
11.0
96
435
M47.9
ICD-10 Finland
Spondylosis, unspecified
44.1
11.0
13
*
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
1.9
10.9
197
1219
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
61.1
10.7
12
*
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
3.1
10.6
60
209
9477
FHL
Cleansing or splitting of a tendon or tendon sheath (eg tenosynovectomy, tenolysis)
111.8
10.4
11
*
NAG40
NOMESCO Finland
Anterior fusion of cervical spine without fixation
111.8
10.4
11
*
M47.82
ICD-10 Finland
Other spondylosis, cervical region
33.1
10.4
13
*
A02BC05
ATC
esomeprazole; systemic
1.9
10.3
190
1178
M54.6
ICD-10 Finland
Pain in thoracic spine
4.0
10.3
40
104
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.0
10.2
150
856
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.7
10.2
334
2499
M13.9
ICD-10 Finland
Arthritis, unspecified
3.8
10.0
42
117
M03BC51
ATC
orphenadrine, combinations; systemic
2.0
10.0
148
844
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.7
9.9
302
2200
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
4.4
9.8
35
84
M54.1
ICD-10 Finland
Radiculopathy
11.6
9.6
17
15
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
5.1
9.5
29
59
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.7
9.5
41
117
S89.9
ICD-10 Finland
Unspecified injury of lower leg
4.4
9.4
33
78
J45.9
ICD-10 Finland
Asthma, unspecified
2.4
9.4
85
388
ABC16
NOMESCO Finland
Microsurgical excision of lumbar intervertebral disc displacement
+∞
9.4
9
*
G55.1*M51.1
ICD-10 Finland
Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions
22.1
9.4
13
6
A02BC01
ATC
omeprazole; systemic
2.0
9.3
124
677
M01AX05
ATC
glucosamine; oral
2.8
9.0
60
232
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
18.9
9.0
13
7
9473
FHL
Local soft tissue removal or exploration (eg Bursa)
18.9
9.0
13
7
N06AX21
ATC
duloxetine; oral
2.8
8.9
56
210
M53.1
ICD-10 Finland
Cervicobrachial syndrome
2.9
8.9
52
187
S43.4
ICD-10 Finland
Sprain and strain of shoulder joint
4.8
8.8
28
60
M02AA15
ATC
diclofenac; topical (antiinflammatory prep., non-steroids for topical use)
3.6
8.8
38
109
L86
ICPC
Back syndrome with radiating pain
5.4
8.7
25
48
S83.2
ICD-10 Finland
Tear of meniscus, current
2.8
8.6
54
202
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
3.2
8.6
45
150
R03DC03
ATC
montelukast; oral
2.2
8.5
87
423
SAA01
NOMESCO Finland
Simple examination of mouth
1.7
8.5
431
3565
R52.2
ICD-10 Finland
Other chronic pain
7.5
8.5
19
26
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.9
8.4
133
774
J01FA06
ATC
roxithromycin; oral
1.7
8.4
202
1354
ABC26
NOMESCO Finland
Open discectomy of lumbar spine
+∞
8.3
8
*
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
2.5
8.3
65
276
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.6
8.2
295
2210
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.3
8.2
80
381
L17
ICPC
Foot/toe symptom/complaint
2.0
8.1
117
657
R06.0
ICD-10 Finland
Dyspnoea
2.0
8.1
104
558
X58
ICD-10 Finland
Exposure to other specified factors
2.1
8.1
94
483
VALMI
NOMESCO Finland
NA
1.8
8.1
166
1057
M54
ICD-10 Finland
Dorsalgia
2.5
7.8
60
255
L08
ICPC
Shoulder symptom/complaint
2.1
7.8
86
434
R53
ICD-10 Finland
Malaise and fatigue
2.0
7.7
102
555
M50.3
ICD-10 Finland
Other cervical disc degeneration
45.5
7.7
9
*
R03BA05
ATC
fluticasone; inhalant
2.0
7.7
100
540
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.6
7.7
54
218
R01AD09
ATC
mometasone; nasal
1.6
7.7
261
1913
R51.80
ICD-10 Finland
Headache
2.1
7.6
87
443
M01AH02
ATC
rofecoxib; oral
2.7
7.5
48
184
A92
ICPC
Allergy/allergic reaction NOS
4.7
7.5
24
53
R01BA52
ATC
pseudoephedrine, combinations; oral
1.8
7.4
146
914
M24.2
ICD-10 Finland
Disorder of ligament
6.1
7.4
19
32
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.1
7.3
85
436
M04AA01
ATC
allopurinol; systemic
2.6
7.3
53
215
NG1BM
NOMESCO Finland
Knee and lower leg MRI examination with 3 Tesla magnet
+∞
7.3
7
*
7231A
ICD-9 Finland
Other disorders of cervical region, Cervicalgia
+∞
7.3
7
*
J01DB01
ATC
cefalexin; oral
1.7
7.3
472
4074
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.1
7.3
89
469
J01DA01
ATC
[U] cefalexin; systemic
1.6
7.3
342
2714
R01AD12
ATC
fluticasone furoate; nasal
1.7
7.2
181
1214
L29
ICPC
Musculoskeletal sympt/complt other
2.9
7.1
41
146
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.7
7.1
156
1009
M77.1
ICD-10 Finland
Lateral epicondylitis
2.6
7.0
50
204
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
5.0
7.0
21
43
SPAT1263
SPAT
Sampling
1.6
7.0
227
1635
1220
FHL
Arthroscopy
3.6
7.0
30
87
R07.4
ICD-10 Finland
Chest pain, unspecified
1.9
7.0
107
615
H02AB04
ATC
methylprednisolone; systemic
2.2
7.0
68
326
NBL00
NOMESCO Finland
Suture or reinsertation of rotator cuff of shoulder
3.8
7.0
28
77
-1
NOMESCO Finland
NA
1.6
6.9
216
1538
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.6
6.9
316
2478
ZXA05
NOMESCO Finland
Left side
1.9
6.9
104
592
M70.4
ICD-10 Finland
Prepatellar bursitis
4.6
6.8
22
49
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
5.4
6.8
19
36
S80.0
ICD-10 Finland
Contusion of knee
2.7
6.8
44
170
NGM20
NOMESCO Finland
Excision of synovial ganglion of knee or lower leg
40.5
6.8
8
*
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
16.9
6.8
10
6
J01FA10
ATC
azithromycin; systemic
1.6
6.7
346
2781
N06AX11
ATC
mirtazapine; oral
1.7
6.7
154
1004
NHL16
NOMESCO Finland
Tenolysis or tenosynovectomy of achilles tendon
22.8
6.7
9
*
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.2
6.6
63
297
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
1.8
6.6
114
679
H02BX01
ATC
methylprednisolone, combinations; systemic
4.4
6.6
22
51
M10.9
ICD-10 Finland
Gout, unspecified
3.4
6.6
30
92
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
1.9
6.6
100
572
NGL20
NOMESCO Finland
Freeing of muscle of knee or lower leg
70.5
6.4
7
*
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.4
6.4
54
240
M94.2
ICD-10 Finland
Chondromalacia
14.5
6.4
10
7
NH1BG
NOMESCO Finland
Ankle and foot MRI examination with high intensity magnet
5.6
6.3
17
31
M01AH03
ATC
valdecoxib; oral
3.3
6.3
30
95
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
+∞
6.3
6
*
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.4
6.2
50
217
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
2.8
6.2
37
136
S18
ICPC
Laceration/cut
1.6
6.2
186
1302
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.6
6.2
43
171
A02BC03
ATC
lansoprazole; oral
1.8
6.2
112
680
A02BA02
ATC
ranitidine; systemic
2.1
6.2
71
366
R50.9
ICD-10 Finland
Fever, unspecified
2.0
6.1
79
426
M01AB08
ATC
etodolac; oral
2.8
6.1
37
138
NG1DA
NOMESCO Finland
X-ray of knees
6.8
6.1
14
21
XKD00
NOMESCO Finland
Uroflowmetry
2.2
6.0
59
283
A01
ICPC
Pain general/multiple sites
3.0
6.0
34
119
A08.4
ICD-10 Finland
Viral intestinal infection, unspecified
3.1
6.0
30
99
Mortality – FinRegistry
↥Association
Association between endpoint M13_PATELLARTEND and mortality.
Females
No dataMales
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_PATELLARTEND | 0.525 [0.4, 0.68] | < 0.001 |
| Birth year | 0.986 [0.98, 1.0] | 0.004 |
During the follow-up period (1.1.1998 — 31.12.2019), 63 out of 2855 males with M13_PATELLARTEND died.
Mortality risk
Mortality risk for people of age
years, who have M13_PATELLARTEND.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | 0.118% |
| 5 | No data | 0.594% |
| 10 | No data | 1.445% |
| 15 | No data | 2.857% |
| 20 | No data | 4.989% |
Relationships between endpoints
↥Index endpoint: M13_PATELLARTEND – Patellar tendinitis
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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