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Spinal osteochondrosis

DOID EFO Endpoint Browser PheWeb

M13_SPINALOSTEOCHON

Endpoint definition

↥

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — M42
  • Hospital discharge: ICD-9 — 7320
  • Cause of death: ICD-10 — M42
  • Cause of death: ICD-9 — 7320

2 out of 7 registries used, show all original rules.

430

4. Check minimum number of events

None

430

5. Include endpoints

None

430

6. Filter based on genotype QC (FinnGen only)

430

Control definitions (FinnGen only)

Control exclude
M13_DORSOPATHY

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M40-M43
Name in latin
Osteochondrosis spinalis

Case counts by codes

↥

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 4271 1626 2630
Only index persons 4030 1537 2493
Unadjusted period prevalence (%)
Whole population 0.06 0.05 0.07
Only index persons 0.08 0.06 0.10
Median age at first event (years)
Whole population 35.52 48.47 27.38
Only index persons 33.50 46.39 25.56

-FinnGen-

Key figures

All Female Male
Number of individuals 430 198 232
Unadjusted period prevalence (%) 0.09 0.07 0.10
Median age at first event (years) 40.21 43.12 37.74

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
396
Matched controls
3960
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M42.0
ICD-10 Finland
Juvenile osteochondrosis of spine
+∞
275.3
231
*
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
76.6
99.7
111
20
M48.0
ICD-10 Finland
Spinal stenosis
162.1
96.1
98
8
M42.1
ICD-10 Finland
Adult osteochondrosis of spine
+∞
87.8
81
*
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
79.6
64.9
72
11
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
43.7
60.9
75
21
N03AX16
ATC
pregabalin; oral
8.2
58.5
151
278
M54.5
ICD-10 Finland
Low back pain
6.6
57.4
184
459
M54.9
ICD-10 Finland
Dorsalgia, unspecified
17.0
56.6
93
70
N03AX12
ATC
gabapentin; oral
11.2
52.2
105
123
M42.9
ICD-10 Finland
Spinal osteochondrosis, unspecified
+∞
51.2
48
*
N02AX02
ATC
tramadol; systemic, rectal
5.2
49.4
216
746
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
190.1
49.1
50
*
7320A
ICD-9 Finland
Osteochondropathies, Juvenile osteochondrosis of spine[MORBUS SCHEUERMANN]
+∞
47.9
45
*
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
265.8
47.1
47
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
17.9
38.0
60
39
M54.4
ICD-10 Finland
Lumbago with sciatica
8.7
35.9
82
115
M03BC01
ATC
orphenadrine (citrate); systemic
4.5
31.6
132
393
M47.82
ICD-10 Finland
Other spondylosis, cervical region
76.4
31.4
35
5
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
9.4
31.2
67
84
M03BX02
ATC
tizanidine; oral
3.3
28.2
269
1534
M54.6
ICD-10 Finland
Pain in thoracic spine
10.5
28.1
56
61
N06AX21
ATC
duloxetine; oral
7.2
27.5
70
114
L03
ICPC
Low back symptom/complaint
4.4
27.3
115
339
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
144.5
25.9
27
*
M43.1
ICD-10 Finland
Spondylolisthesis
75.0
25.1
28
*
M47.9
ICD-10 Finland
Spondylosis, unspecified
96.4
25.0
27
*
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
3.1
24.8
201
984
L02
ICPC
Back symptom/complaint
6.9
24.8
65
110
N06AA09
ATC
amitriptyline; systemic
7.6
23.2
56
84
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
31.1
22.2
29
10
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
+∞
22.1
21
*
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
121.8
21.8
23
*
M54.3
ICD-10 Finland
Sciatica
18.8
21.7
33
19
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
15.9
21.6
35
24
M01AH05
ATC
etoricoxib; oral
2.8
21.5
243
1427
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
34.6
20.4
26
8
M53.1
ICD-10 Finland
Cervicobrachial syndrome
6.3
19.6
54
97
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
33.2
19.5
25
8
M01AH01
ATC
celecoxib; oral (coxibs)
4.1
19.4
83
241
N06AX11
ATC
mirtazapine; oral
2.9
18.4
146
669
A02BC02
ATC
pantoprazole; systemic
2.6
17.9
250
1583
NAG40
NOMESCO Finland
Anterior fusion of cervical spine without fixation
+∞
17.8
17
*
M79.6
ICD-10 Finland
Pain in limb
2.8
17.8
146
684
ABC16
NOMESCO Finland
Microsurgical excision of lumbar intervertebral disc displacement
188.1
17.7
18
*
M50.3
ICD-10 Finland
Other cervical disc degeneration
188.1
17.7
18
*
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
18.0
17.6
27
16
N02BE01
ATC
paracetamol; systemic, rectal
3.2
17.6
340
2594
M01AH02
ATC
rofecoxib; oral
4.5
17.5
65
164
M54.2
ICD-10 Finland
Cervicalgia
8.6
17.5
38
48
R51.80
ICD-10 Finland
Headache
3.8
17.1
78
238
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
3.0
16.5
114
471
M54.1
ICD-10 Finland
Radiculopathy
31.6
16.3
21
7
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.6
16.2
149
737
A02BC05
ATC
esomeprazole; systemic
2.5
15.8
163
856
M40.2
ICD-10 Finland
Other and unspecified kyphosis
+∞
15.7
15
*
M01AE03
ATC
ketoprofen; systemic, rectal
2.6
15.7
154
788
N02AJ06
ATC
codeine and paracetamol; systemic
2.6
15.6
154
790
Z01.8
ICD-10 Finland
Other specified special examinations
3.1
15.4
99
390
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.9
15.3
67
197
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.8
15.3
118
521
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
59.0
14.9
17
*
ABC56
NOMESCO Finland
Decompression of lumbar spinal canal and nerve roots
+∞
14.7
14
*
N06AX16
ATC
venlafaxine; oral
3.5
14.4
73
242
R03AC02
ATC
salbutamol; inhalant
2.3
13.8
209
1305
M01AB05
ATC
diclofenac; systemic, rectal
2.3
13.6
257
1773
R53
ICD-10 Finland
Malaise and fatigue
2.9
13.2
88
351
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
23.5
13.0
18
8
N06CA01
ATC
amitriptyline and psycholeptics; systemic
4.2
12.9
50
131
M01AE02
ATC
naproxen; oral, rectal
2.2
12.9
225
1484
ABC26
NOMESCO Finland
Open discectomy of lumbar spine
+∞
12.6
12
*
A02BC03
ATC
lansoprazole; oral
2.6
12.6
108
500
G56.0
ICD-10 Finland
Carpal tunnel syndrome
3.8
12.5
54
156
M45
ICD-10 Finland
Ankylosing spondylitis
134.1
12.5
13
*
N05CF01
ATC
zopiclone; oral
2.4
12.4
126
639
M03BC51
ATC
orphenadrine, combinations; systemic
2.5
12.4
114
549
R06.0
ICD-10 Finland
Dyspnoea
2.6
12.2
98
438
SPAT1097
SPAT
Recording of ECG
3.4
12.1
62
207
N05AH04
ATC
quetiapine; oral
2.8
12.0
85
352
M41.9
ICD-10 Finland
Scoliosis, unspecified
67.0
11.7
13
*
H02AB06
ATC
prednisolone; systemic
2.2
11.7
172
1036
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
23.7
11.7
16
7
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
10.5
11.6
22
22
M25.5
ICD-10 Finland
Pain in joint
2.5
11.5
109
530
NAG53
NOMESCO Finland
Posterior or lateral fusion of thoracic spine with fixation, more than 3 vertebraea
+∞
11.5
11
*
M43.0
ICD-10 Finland
Spondylolysis
123.5
11.5
12
*
A02BC01
ATC
omeprazole; systemic
2.5
11.4
104
496
M01AB55
ATC
diclofenac, combinations; oral
5.4
11.4
34
68
Z50.1
ICD-10 Finland
Other physical therapy
5.3
11.2
34
69
J01AA02
ATC
doxycycline; systemic
2.2
11.2
292
2225
G44.2
ICD-10 Finland
Tension-type headache
3.4
11.2
56
183
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
4.5
11.0
39
94
C07AA05
ATC
propranolol; systemic
2.6
10.7
88
394
G55.1*M51.1
ICD-10 Finland
Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions
61.7
10.7
12
*
N06AB04
ATC
citalopram; systemic
2.6
10.7
86
383
R52.2
ICD-10 Finland
Other chronic pain
10.5
10.6
20
20
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
14.7
10.6
17
12
G55.2*M47.9
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
+∞
10.5
10
*
M47.1
ICD-10 Finland
Other spondylosis with myelopathy
+∞
10.5
10
*
L86
ICPC
Back syndrome with radiating pain
7.4
10.4
24
34
M01AX17
ATC
nimesulide; oral
2.5
10.4
92
430
G47.3
ICD-10 Finland
Sleep apnoea
2.4
10.3
95
452
UJF32
NOMESCO Finland
Coloscopy
2.4
10.2
97
468
SPAT1256
SPAT
Intramuscular and subcutaneous injection
2.1
10.2
158
957
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
7.6
10.1
23
32
SPAT1301
SPAT
No procedures
2.2
10.1
125
687
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
41.2
10.0
12
*
N02AA05
ATC
oxycodone; systemic
3.1
10.0
56
198
M79.0
ICD-10 Finland
Rheumatism, unspecified
9.9
9.9
19
20
M75.1
ICD-10 Finland
Rotator cuff syndrome
2.5
9.6
85
396
Z3226
NOMESCO Finland
Physiotherapist
2.6
9.6
74
319
R07.4
ICD-10 Finland
Chest pain, unspecified
2.3
9.5
97
487
J01DB01
ATC
cefalexin; oral
2.2
9.5
320
2606
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
30.8
9.5
12
*
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
2.0
9.4
200
1358
7227C
ICD-9 Finland
Intervertebral disk disorders, Intervertebral disk disorder with myelopathy[SYNDROMA ISCHIADICUM]
+∞
9.4
9
*
SPAT1250
SPAT
Comprehensive monitoring of chronic illness
2.3
9.4
100
511
N04BC05
ATC
pramipexole; oral
5.0
9.2
29
62
M01AC06
ATC
meloxicam; systemic, rectal
2.1
9.2
127
726
J31.0
ICD-10 Finland
Chronic rhinitis
4.0
9.1
36
97
Z50.8
ICD-10 Finland
Care involving use of other rehabilitation procedures
4.2
9.1
34
87
A01
ICPC
Pain general/multiple sites
4.2
9.1
34
87
M79.1
ICD-10 Finland
Myalgia
3.0
9.1
55
204
R42
ICD-10 Finland
Dizziness and giddiness
2.5
9.0
78
357
M35.7
ICD-10 Finland
Hypermobility syndrome
24.7
9.0
12
5
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
2.1
8.9
124
711
R01AD08
ATC
fluticasone; nasal
2.1
8.9
115
639
N05BA12
ATC
alprazolam; oral
3.3
8.8
44
144
L28
ICPC
Limited function/disability (L)
2.9
8.8
55
210
J01DA01
ATC
[U] cefalexin; systemic
1.9
8.8
233
1700
M54
ICD-10 Finland
Dorsalgia
3.2
8.7
45
151
M51.9
ICD-10 Finland
Intervertebral disc disorder, unspecified
51.1
8.7
10
*
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.4
8.7
82
395
C07AB07
ATC
bisoprolol; oral
1.9
8.6
156
991
M53.0
ICD-10 Finland
Cervicocranial syndrome
3.9
8.6
35
97
WX110
NOMESCO Finland
Local anesthesy
1.9
8.6
272
2108
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
2.1
8.6
113
630
N06AX03
ATC
mianserin; oral
6.2
8.6
22
37
N05CD07
ATC
temazepam; oral
3.1
8.5
48
170
A02BA02
ATC
ranitidine; systemic
2.6
8.5
66
287
M41.1
ICD-10 Finland
Juvenile idiopathic scoliosis
91.9
8.4
9
*
NAG63
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, more than 3 vertebraea
+∞
8.4
8
*
7245A
ICD-9 Finland
Other and unspecified disorders of back, Backache, unspecified
+∞
8.4
8
*
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
11.1
8.4
15
14
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
3.2
8.4
44
150
EBA00
NOMESCO Finland
Extraction of tooth
2.0
8.3
135
820
N06AB10
ATC
escitalopram; oral
2.3
8.3
83
409
R4110
NOMESCO Finland
Physiotherapy
2.2
8.2
97
518
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.9
8.2
209
1491
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
7.1
8.2
19
28
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.3
8.2
83
414
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.9
8.1
186
1275
M70.6
ICD-10 Finland
Trochanteric bursitis
3.5
8.0
37
114
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.9
8.0
151
966
M79.7
ICD-10 Finland
Fibromyalgia
8.0
8.0
17
22
N02AJ13
ATC
tramadol and paracetamol; systemic
13.4
7.9
13
10
N05BA01
ATC
diazepam; systemic, rectal
2.7
7.9
54
218
C03CA01
ATC
furosemide; systemic
2.2
7.9
87
449
L01
ICPC
Neck symptom/complaint
2.8
7.9
52
203
M19.0
ICD-10 Finland
Primary arthrosis of other joints
3.3
7.8
38
122
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.6
7.8
61
262
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.7
7.8
55
224
M47.81
ICD-10 Finland
Other spondylosis, occipito-atlanto-axial region
45.9
7.7
9
*
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.8
7.7
221
1625
N03AE01
ATC
clonazepam; systemic
3.8
7.7
31
86
SPAT1263
SPAT
Sampling
1.9
7.7
162
1073
WZB00
NOMESCO Finland
Telephone receipt or other advice
2.0
7.6
113
660
UJD02
NOMESCO Finland
Gastroscopy
4.8
7.5
24
53
N05BA04
ATC
oxazepam; oral
2.1
7.5
92
497
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
81.6
7.4
8
*
M41.2
ICD-10 Finland
Other idiopathic scoliosis
81.6
7.4
8
*
G43.9
ICD-10 Finland
Migraine, unspecified
4.2
7.4
27
68
J45.9
ICD-10 Finland
Asthma, unspecified
2.4
7.4
64
293
R1250
NOMESCO Finland
Evaluation of functional capability
8.6
7.4
15
18
N05CF02
ATC
zolpidem; oral
2.4
7.4
66
306
G55.1*M51.9
ICD-10 Finland
Nerve root and plexus compressions in intervertebral disc disorders (M50-M51+)
+∞
7.3
7
*
NAG65
NOMESCO Finland
Anterior and posterior fusion of lumbar spine
+∞
7.3
7
*
M40.1
ICD-10 Finland
Other secondary kyphosis
+∞
7.3
7
*
NA1BA
NOMESCO Finland
Cervical spine extensive X-ray examination without contrast
+∞
7.3
7
*
M51.8
ICD-10 Finland
Other specified intervertebral disc disorders
+∞
7.3
7
*
A07EC01
ATC
sulfasalazine; oral, rectal
3.5
7.3
33
101
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.6
7.2
53
223
M54.0
ICD-10 Finland
Panniculitis affecting regions of neck and back
30.6
7.2
9
*
SPAT1153
SPAT
Removal of sutures
2.0
7.2
108
630
H01
ICPC
Ear pain/earache
2.9
7.1
42
155
M24.4
ICD-10 Finland
Recurrent dislocation and subluxation of joint
12.3
7.1
12
10
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.4
7.1
63
293
M01AB08
ATC
etodolac; oral
3.8
7.0
28
77
K02.1
ICD-10 Finland
Caries of dentine
1.8
7.0
225
1695
R2130
NOMESCO Finland
Counselling and guidance which enhance independent living
3.1
6.9
37
128
SPAT1212
SPAT
Extensive examination of musculoskeletal system
3.4
6.9
32
100
J01FA10
ATC
azithromycin; systemic
1.7
6.8
222
1671
R52.1
ICD-10 Finland
Chronic intractable pain
40.8
6.8
8
*
R55
ICD-10 Finland
Syncope and collapse
2.8
6.7
42
159
I25.1
ICD-10 Finland
Atherosclerotic heart disease
2.3
6.7
65
316
L08
ICPC
Shoulder symptom/complaint
2.3
6.6
62
296
SAA01
NOMESCO Finland
Simple examination of mouth
1.8
6.6
269
2160
WX105
NOMESCO Finland
Surface analgesia on skin or mucosa
2.8
6.6
40
151
SFA40
NOMESCO Finland
Replacement of krone of tooth
2.2
6.6
74
381
R03AK06
ATC
salmeterol and fluticasone; inhalant
2.5
6.6
52
228
SPAT1310
SPAT
Counselling related to known health issue
1.9
6.6
115
708
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.0
6.6
99
575
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.7
6.5
201
1483
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
7.6
6.5
14
19
WYA30
NOMESCO Finland
Preparations for expected poor cooperation
3.0
6.4
36
126
ABD32
NOMESCO Finland
Implantation of temporary spinal stimulation device
70.9
6.4
7
*
N06AB03
ATC
fluoxetine; oral
2.6
6.4
47
195
M77.1
ICD-10 Finland
Lateral epicondylitis
3.2
6.4
32
106
WX408
NOMESCO Finland
General anesthesy, balanced
1.9
6.4
101
598
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
3.1
6.4
34
118
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
3.0
6.4
36
128
M16.1
ICD-10 Finland
Other primary coxarthrosis
3.0
6.4
36
128
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
5.7
6.4
17
31
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.9
6.3
99
584
R52.9
ICD-10 Finland
Pain, unspecified
3.1
6.3
33
113
J01CA04
ATC
amoxicillin; systemic
1.8
6.3
311
2631
F34.1
ICD-10 Finland
Dysthymia
4.3
6.3
22
54
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
4.1
6.3
23
59
205
Kela drug reimbursment
Chronic hypertension
2.0
6.3
85
473
M76.8
ICD-10 Finland
Other enthesopathies of lower limb, excluding foot
18.4
6.3
9
5
R01AD09
ATC
mometasone; nasal
1.7
6.3
164
1147
7225A
ICD-9 Finland
Intervertebral disk disorders, Degeneration of thoracic or lumbar intervertebral disk[DEGENERATIO DISCI INTERVERTEBRALIS THORAC SEU LUMB]
+∞
6.3
6
*
M53.2
ICD-10 Finland
Spinal instabilities
+∞
6.3
6
*
AB5BT
NOMESCO Finland
Blockage of nerv root with X-ray guidance
+∞
6.3
6
*
72870
ICD-8 Finland
Vertebrogenic pain syndrome, Lumbalgia
+∞
6.3
6
*
M96.1
ICD-10 Finland
Postlaminectomy syndrome, not elsewhere classified
+∞
6.3
6
*
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.4
6.2
54
246
N06AX12
ATC
bupropion; oral
3.2
6.2
31
103
SPAT1254
SPAT
Administration of medicine
2.3
6.2
56
261
Z3231
NOMESCO Finland
Registered nurse
1.9
6.1
102
614
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.1
6.1
32
110
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
3.3
6.1
29
93
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.8
6.1
39
151
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.7
6.1
143
967
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
4.7
6.1
19
42
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
5.7
6.1
16
29

Mortality – FinRegistry

↥

Association

Association between endpoint M13_SPINALOSTEOCHON and mortality.

Females

Parameter HR [95% CI] p-value
M13_SPINALOSTEOCHON 1.195 [1.02, 1.41] 0.031
Birth year 0.994 [0.99, 1.0] 0.182

During the follow-up period (1.1.1998 — 31.12.2019), 218 out of 1341 females with M13_SPINALOSTEOCHON died.

Males

Parameter HR [95% CI] p-value
M13_SPINALOSTEOCHON 1.222 [1.01, 1.48] 0.041
Birth year 0.986 [0.98, 1.0] 0.005

During the follow-up period (1.1.1998 — 31.12.2019), 212 out of 1938 males with M13_SPINALOSTEOCHON died.

Mortality risk

Mortality risk for people of age

years, who have M13_SPINALOSTEOCHON.

N-year risk Females Males
1 0.115% 0.219%
5 0.877% 1.405%
10 1.929% 3.729%
15 3.596% 6.762%
20 6.181% 11.273%

Relationships between endpoints

↥

Index endpoint: M13_SPINALOSTEOCHON – Spinal osteochondrosis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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