No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
1117 |
4. Check minimum number of eventsNone |
1117 |
5. Include endpointsNone |
1117 |
6. Filter based on genotype QC (FinnGen only) |
1117 |
Control definitions (FinnGen only)
- Control exclude
- M13_DORSOPATHY
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- M53
- Name in latin
- Instabilitates dorsi
Similar endpoints
↥List of similar endpoints to
Spinal instabilities
based on the number of shared cases.
Similar with more cases:
- Other dorsopathies, not elsewhere classified
- Dorsopathies
- Diseases of the musculoskeletal system and connective tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 5536 | 3333 | 2184 |
| Only index persons | 5425 | 3281 | 2144 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.08 | 0.10 | 0.06 |
| Only index persons | 0.11 | 0.12 | 0.08 |
| Median age at first event (years) | |||
| Whole population | 47.96 | 49.06 | 46.26 |
| Only index persons | 47.85 | 48.96 | 46.14 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1117 | 730 | 387 |
| Unadjusted period prevalence (%) | 0.22 | 0.25 | 0.17 |
| Median age at first event (years) | 50.60 | 50.24 | 51.27 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1031
- Matched controls
- 10311
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M53.2
ICD-10 Finland
Spinal instabilities
+∞
323.0
1031
5
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
137.8
323.0
394
46
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
50.8
323.0
428
142
NAG62
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, 2-3 vertebraea
+∞
323.0
311
*
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
154.1
323.0
506
64
M48.0
ICD-10 Finland
Spinal stenosis
169.8
323.0
385
36
NA3EA
NOMESCO Finland
Lumbar spine X-ray examination with flexion
686.7
316.3
297
6
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
69.7
302.3
343
73
N03AX16
ATC
pregabalin; oral
13.8
279.0
575
861
M54.4
ICD-10 Finland
Lumbago with sciatica
18.3
251.6
422
375
NA3CG
NOMESCO Finland
Lumbar spine extensive MRI examination with high intensity magnet
112.5
227.2
242
28
M54.5
ICD-10 Finland
Low back pain
9.1
218.3
603
1377
N03AX12
ATC
gabapentin; oral
14.9
213.8
391
406
N02AX02
ATC
tramadol; systemic, rectal
8.2
209.1
719
2252
ABC36
NOMESCO Finland
Decompression of lumbar nerve roots
283.7
207.1
205
9
M47.2
ICD-10 Finland
Other spondylosis with radiculopathy
216.6
206.6
208
12
NA3AD
NOMESCO Finland
Lumbar spine and sacrum CT examination
141.0
195.5
204
18
M43.1
ICD-10 Finland
Spondylolisthesis
123.9
181.4
192
19
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
14.2
155.3
282
266
ABC16
NOMESCO Finland
Microsurgical excision of lumbar intervertebral disc displacement
1577.4
144.3
137
*
L03
ICPC
Low back symptom/complaint
6.1
124.5
416
1029
M54.9
ICD-10 Finland
Dorsalgia, unspecified
11.8
117.3
230
244
M50.1
ICD-10 Finland
Cervical disc disorder with radiculopathy
78.0
115.7
130
19
M03BX02
ATC
tizanidine; oral
5.0
106.8
832
4717
N06AX21
ATC
duloxetine; oral
8.6
105.1
250
371
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
4.1
99.2
641
2943
N06AA09
ATC
amitriptyline; systemic
8.2
98.8
241
369
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
21.2
97.5
147
80
M47.9
ICD-10 Finland
Spondylosis, unspecified
89.9
95.1
105
13
M54.1
ICD-10 Finland
Radiculopathy
33.5
84.4
111
37
M47.82
ICD-10 Finland
Other spondylosis, cervical region
60.0
83.9
98
18
M01AH05
ATC
etoricoxib; oral
3.8
81.9
772
4526
7227C
ICD-9 Finland
Intervertebral disk disorders, Intervertebral disk disorder with myelopathy[SYNDROMA ISCHIADICUM]
+∞
70.6
67
*
M43.0
ICD-10 Finland
Spondylolysis
365.8
69.5
69
*
M54.3
ICD-10 Finland
Sciatica
15.4
68.7
116
84
N02BE01
ATC
paracetamol; systemic, rectal
5.6
67.7
958
7219
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
3.6
65.8
388
1491
N02AJ06
ATC
codeine and paracetamol; systemic
3.2
63.6
487
2260
L86
ICPC
Back syndrome with radiating pain
12.3
62.7
117
106
NAG40
NOMESCO Finland
Anterior fusion of cervical spine without fixation
634.2
61.4
60
*
M01AB05
ATC
diclofenac; systemic, rectal
3.3
60.9
800
5301
M47.80
ICD-10 Finland
Other spondylosis, multiple sites in spine
48.2
59.4
72
16
M03BC01
ATC
orphenadrine (citrate); systemic
3.5
58.7
341
1273
M53.1
ICD-10 Finland
Cervicobrachial syndrome
5.8
57.1
175
349
N02AA05
ATC
oxycodone; systemic
4.7
57.1
219
562
M01AE02
ATC
naproxen; oral, rectal
2.9
56.8
685
4173
M79.0
ICD-10 Finland
Rheumatism, unspecified
13.9
56.4
99
78
M54.2
ICD-10 Finland
Cervicalgia
8.8
54.5
122
155
M75.1
ICD-10 Finland
Rotator cuff syndrome
3.4
53.9
328
1253
M51.8
ICD-10 Finland
Other specified intervertebral disc disorders
533.6
51.9
51
*
G55.1*M51.1
ICD-10 Finland
Compression of nerve roots and nerve plexus in disc diseases in the lumbar region and other regions
86.2
51.5
57
7
TAB20
NOMESCO Finland
Epidural puncture
83.0
49.4
55
7
A02BC02
ATC
pantoprazole; systemic
2.8
49.2
729
4815
M25.5
ICD-10 Finland
Pain in joint
3.0
49.2
378
1680
R52.1
ICD-10 Finland
Chronic intractable pain
54.7
48.2
57
11
M01AC06
ATC
meloxicam; systemic, rectal
2.7
47.8
471
2436
M01AH01
ATC
celecoxib; oral (coxibs)
3.6
47.8
255
868
M79.6
ICD-10 Finland
Pain in limb
2.8
47.8
430
2103
M51.9
ICD-10 Finland
Intervertebral disc disorder, unspecified
64.4
47.8
55
9
9211
FHL
Exploration or removal of diskusprolapse
+∞
47.2
45
*
M01AE03
ATC
ketoprofen; systemic, rectal
2.7
46.2
464
2414
ZXC95
NOMESCO Finland
Use of surgical navigator
23.4
45.9
66
30
NAG63
NOMESCO Finland
Posterior fusion of lumbar spine with fixation, more than 3 vertebraea
467.4
45.6
45
*
A02BC05
ATC
esomeprazole; systemic
2.6
45.2
490
2650
F45.4
ICD-10 Finland
Persistent somatoform pain disorder
28.1
44.7
61
23
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.9
44.7
348
1540
M96.1
ICD-10 Finland
Postlaminectomy syndrome, not elsewhere classified
456.5
44.6
44
*
M50.3
ICD-10 Finland
Other cervical disc degeneration
33.4
43.7
57
18
SPAT1153
SPAT
Removal of sutures
2.7
43.1
387
1864
NAG66
NOMESCO Finland
Posterior interbody fusion of lumbar spine, 2 vertebrae
+∞
43.0
41
*
S18
ICPC
Laceration/cut
2.5
42.1
483
2665
A02BC03
ATC
lansoprazole; oral
2.8
42.0
351
1612
N06AX16
ATC
venlafaxine; oral
3.6
41.7
217
717
M70.6
ICD-10 Finland
Trochanteric bursitis
4.2
40.9
173
477
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
2.6
40.8
407
2067
ABC26
NOMESCO Finland
Open discectomy of lumbar spine
412.9
40.4
40
*
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
3.5
40.3
217
734
ZXM20
NOMESCO Finland
Intraoperative use of computerised tomography
145.7
40.0
42
*
M47.1
ICD-10 Finland
Other spondylosis with myelopathy
+∞
39.8
38
*
M01AH02
ATC
rofecoxib; oral
3.9
39.8
182
538
NA1CG
NOMESCO Finland
Cervical spine extensive MRI examination with high intensity magnet
28.4
39.8
54
20
ABD30
NOMESCO Finland
Implantation of spinal stimulation device
42.8
39.7
49
12
M01AX17
ATC
nimesulide; oral
2.8
39.4
314
1392
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
6.3
39.2
110
193
NA2BG
NOMESCO Finland
Thoracal spine MRI examination with high intensity magnet
20.1
39.2
59
31
NF1AA
NOMESCO Finland
Hip X-ray examination
5.3
38.9
127
268
Z50.9
ICD-10 Finland
Care involving use of rehabilitation procedure, unspecified
8.0
38.1
89
120
N02AC04
ATC
dextropropoxyphene; oral
12.3
37.0
68
59
M03BC51
ATC
orphenadrine, combinations; systemic
2.5
36.5
364
1821
N06CA01
ATC
amitriptyline and psycholeptics; systemic
4.0
36.4
157
439
R52.2
ICD-10 Finland
Other chronic pain
10.3
36.3
73
76
Z50.1
ICD-10 Finland
Other physical therapy
6.2
36.1
102
180
M35.7
ICD-10 Finland
Hypermobility syndrome
24.3
36.0
51
22
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
11.7
35.1
66
60
ABC56
NOMESCO Finland
Decompression of lumbar spinal canal and nerve roots
186.3
35.0
36
*
R51.80
ICD-10 Finland
Headache
3.4
34.6
188
633
G56.0
ICD-10 Finland
Carpal tunnel syndrome
3.4
34.6
184
611
L28
ICPC
Limited function/disability (L)
3.5
34.3
178
580
N06AX11
ATC
mirtazapine; oral
2.5
34.2
366
1887
M54
ICD-10 Finland
Dorsalgia
3.7
33.2
156
468
GD1AA
NOMESCO Finland
Thorax X-ray examination
2.3
32.9
456
2662
M01AB08
ATC
etodolac; oral
4.5
32.5
123
302
M54.6
ICD-10 Finland
Pain in thoracic spine
6.1
32.3
91
160
M54.8
ICD-10 Finland
Other dorsalgia
8.4
32.1
72
91
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
2.9
32.1
225
904
H02AB06
ATC
prednisolone; systemic
2.2
31.2
499
3089
UJF32
NOMESCO Finland
Coloscopy
2.5
31.1
293
1396
N06AA10
ATC
nortriptyline; systemic
11.8
31.1
58
52
NAU20
NOMESCO Finland
Removal of internal fixation device from spine or neck
72.2
31.1
35
5
L02
ICPC
Back symptom/complaint
4.0
31.0
135
378
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
2.2
30.8
454
2702
M01AB51
ATC
indometacin, combinations; oral, rectal
10.4
30.2
60
61
M19.0
ICD-10 Finland
Primary arthrosis of other joints
3.8
30.1
136
393
J45.9
ICD-10 Finland
Asthma, unspecified
2.9
29.6
208
830
M79.7
ICD-10 Finland
Fibromyalgia
8.9
29.1
63
75
NA3CF
NOMESCO Finland
Lumbar spine extensive MRI examination with median intensity magnet
300.0
28.9
29
*
L01
ICPC
Neck symptom/complaint
3.3
28.8
160
544
G55.2*M47.9
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
106.4
28.8
31
*
L08
ICPC
Shoulder symptom/complaint
2.7
28.7
219
921
WX408
NOMESCO Finland
General anesthesy, balanced
2.4
28.7
315
1618
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
6.8
28.6
74
116
N05CF01
ATC
zopiclone; oral
2.3
28.5
345
1858
M01AB55
ATC
diclofenac, combinations; oral
4.9
28.5
98
218
NA7EA
NOMESCO Finland
Scoliosis X-ray examination
56.7
28.3
33
6
M17.1
ICD-10 Finland
Other primary gonarthrosis
2.6
28.3
240
1073
G55.1*M51.9
ICD-10 Finland
Nerve root and plexus compressions in intervertebral disc disorders (M50-M51+)
149.0
27.8
29
*
SPAT1216
SPAT
Assessment of functional ability
3.1
27.7
172
631
A01
ICPC
Pain general/multiple sites
4.6
27.7
100
234
R03AC02
ATC
salbutamol; inhalant
2.1
27.6
557
3734
Z01.8
ICD-10 Finland
Other specified special examinations
2.5
27.3
249
1156
AB5CT
NOMESCO Finland
Blockage of nerv root with CT guidance
+∞
27.2
26
*
M75.4
ICD-10 Finland
Impingement syndrome of shoulder
4.4
26.8
102
251
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
3.8
26.8
120
343
M01AX05
ATC
glucosamine; oral
2.6
26.7
218
948
R06.0
ICD-10 Finland
Dyspnoea
2.5
26.6
251
1184
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
3.2
26.5
149
511
AA1AD
NOMESCO Finland
CT of head and brain
2.5
26.4
244
1138
N03AE01
ATC
clonazepam; systemic
4.8
26.2
91
204
ZXM10
NOMESCO Finland
Intraoperative use of conventional X-ray imaging
5.0
26.1
87
187
J01DB01
ATC
cefalexin; oral
2.3
25.9
855
6962
G44.2
ICD-10 Finland
Tension-type headache
3.0
25.6
163
608
EB1AA
NOMESCO Finland
Tooth X-ray examination
2.0
25.6
603
4247
M02AA07
ATC
piroxicam; topical
2.1
25.4
391
2317
NA3DG
NOMESCO Finland
Lumbar spine very extensive MRI examination with high intensity magnet
51.4
25.4
30
6
Z01.5
ICD-10 Finland
Diagnostic skin and sensitization tests
3.4
25.2
133
434
F32.9
ICD-10 Finland
Depressive episode, unspecified
3.1
24.8
152
550
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.4
24.8
243
1166
J01.0
ICD-10 Finland
Acute maxillary sinusitis
2.4
24.7
251
1225
SPAT1229
SPAT
Assessment of need for aid
4.2
24.6
98
252
H02AB04
ATC
methylprednisolone; systemic
2.8
24.5
177
714
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
20.7
24.4
36
18
NAG61
NOMESCO Finland
Posterior fusion of lumbar spine without fixation
+∞
24.0
23
*
ABD32
NOMESCO Finland
Implantation of temporary spinal stimulation device
31.9
23.8
31
10
SAA01
NOMESCO Finland
Simple examination of mouth
2.0
23.8
746
5793
ZZH40
NOMESCO Finland
Substitute of bone
27.5
23.7
32
12
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.6
23.6
189
808
M53.0
ICD-10 Finland
Cervicocranial syndrome
3.8
23.5
104
294
XA402
NOMESCO Finland
ENMG
8.4
23.4
52
65
J01AA02
ATC
doxycycline; systemic
2.1
23.4
820
6638
F32.2
ICD-10 Finland
Severe depressive episode without psychotic symptoms
4.0
23.2
98
266
R42
ICD-10 Finland
Dizziness and giddiness
2.5
23.0
212
981
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
10.4
23.0
45
45
SAA02
NOMESCO Finland
Basic examination of mouth
2.0
22.9
675
5072
L13
ICPC
Hip symptom/complaint
2.7
22.7
167
678
A02BC01
ATC
omeprazole; systemic
2.2
22.7
285
1528
M45
ICD-10 Finland
Ankylosing spondylitis
46.1
22.4
27
6
M01AX01
ATC
nabumetone; oral
5.6
22.4
67
127
M01AE01
ATC
ibuprofen; systemic, rectal
2.8
22.3
946
8259
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.1
22.3
336
1949
J01FF01
ATC
clindamycin; systemic
2.1
21.8
297
1650
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
4.1
21.5
86
222
X59
ICD-10 Finland
Exposure to unspecified factor
2.4
21.5
203
949
M79.1
ICD-10 Finland
Myalgia
2.8
21.3
150
594
ZZH21
NOMESCO Finland
Graft of patients own bone, small pieces
9.0
21.3
45
52
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.9
21.1
518
3593
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
3.4
21.0
106
333
NE1BG
NOMESCO Finland
Pelvic, hip and femur MRI examination with high intensity magnet
7.1
21.0
52
77
SPAT1263
SPAT
Sampling
1.9
21.0
413
2643
N02AJ13
ATC
tramadol and paracetamol; systemic
10.9
20.5
39
37
P01AB01
ATC
metronidazole; oral, rectal
1.9
20.4
429
2807
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
2.4
20.4
186
851
WZB00
NOMESCO Finland
Telephone receipt or other advice
2.0
20.3
316
1844
R07.4
ICD-10 Finland
Chest pain, unspecified
2.2
20.1
255
1363
NE1AA
NOMESCO Finland
Pelvis X-ray examination
4.3
20.1
76
186
G47.3
ICD-10 Finland
Sleep apnoea
2.2
20.0
230
1178
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
9.1
20.0
42
48
SPAT1220
SPAT
Assessment of need for rehabilitation and/or rehabilitation plan
4.0
20.0
83
222
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
3.2
19.9
109
364
N05AH04
ATC
quetiapine; oral
2.5
19.9
173
769
J01DA01
ATC
[U] cefalexin; systemic
1.8
19.7
647
4915
NJ3NA
NOMESCO Finland
Measurement of difference in extremity lengty with X-ray
8.2
19.7
44
56
G54.0
ICD-10 Finland
Brachial plexus disorders
7.1
19.6
48
70
A02BA04
ATC
nizatidine; systemic
3.5
19.6
97
300
M53.9
ICD-10 Finland
Dorsopathy, unspecified
107.1
19.6
21
*
NBG15
NOMESCO Finland
Acromioplastia, arthroscopic
3.8
19.5
86
242
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.8
19.5
544
3905
X58
ICD-10 Finland
Exposure to other specified factors
2.6
19.3
151
634
M23.2
ICD-10 Finland
Derangement of meniscus due to old tear or injury
2.7
19.3
145
596
B01AF01
ATC
rivaroxaban; oral
2.8
18.9
130
505
NJ2MA
NOMESCO Finland
Measurement of mechanical axis of lower leg with X-ray
3.5
18.8
90
271
R06AE07
ATC
cetirizine; oral
1.8
18.8
464
3180
7245A
ICD-9 Finland
Other and unspecified disorders of back, Backache, unspecified
+∞
18.8
18
*
ABC30
NOMESCO Finland
Decompression of cervical nerve roots
+∞
18.8
18
*
M46.9
ICD-10 Finland
Inflammatory spondylopathy, unspecified
+∞
18.8
18
*
Z01.2
ICD-10 Finland
Dental examination
1.8
18.7
429
2867
M51.2
ICD-10 Finland
Other specified intervertebral disc displacement
193.3
18.6
19
*
M16.1
ICD-10 Finland
Other primary coxarthrosis
3.0
18.6
111
394
WX110
NOMESCO Finland
Local anesthesy
1.8
18.5
701
5521
R01AD09
ATC
mometasone; nasal
1.8
18.4
475
3297
NA1AD
NOMESCO Finland
Cervical spine CT examination
5.6
18.4
54
101
R01BA52
ATC
pseudoephedrine, combinations; oral
1.9
18.3
347
2164
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.8
18.3
128
501
L15
ICPC
Knee symptom/complaint
2.2
18.2
225
1184
H04.10
ICD-10 Finland
Dry eye syndrome
2.8
18.2
124
478
C07AB07
ATC
bisoprolol; oral
1.8
18.1
428
2879
SPAT1256
SPAT
Intramuscular and subcutaneous injection
1.8
18.0
420
2813
TAC99
NOMESCO Finland
Other blockade for chronic pain
33.5
18.0
23
7
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.7
17.9
134
548
M02AA10
ATC
ketoprofen; topical
2.3
17.7
179
858
M54.0
ICD-10 Finland
Panniculitis affecting regions of neck and back
14.9
17.7
29
20
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
3.4
17.5
89
282
N06AB04
ATC
citalopram; systemic
2.1
17.3
232
1262
Y83
ICD-10 Finland
Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
3.3
17.2
90
291
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
3.7
17.2
76
215
N03AX09
ATC
lamotrigine; oral
4.1
17.0
68
176
R01AD08
ATC
fluticasone; nasal
1.9
17.0
310
1895
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.8
17.0
604
4595
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.9
16.8
295
1779
R29.8
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
3.2
16.7
93
313
NAG41
NOMESCO Finland
Anterior fusion of cervical spine with fixation
91.6
16.6
18
*
AEA00
NOMESCO Finland
Replacement of impulse generator of stimulation device in the nervous system
91.6
16.6
18
*
XX2CT
NOMESCO Finland
Other injection with CT guidance
172.6
16.5
17
*
WZA90
NOMESCO Finland
Other doctors statement
2.0
16.5
239
1336
M17.0
ICD-10 Finland
Primary gonarthrosis, bilateral
2.5
16.5
142
624
A02BC04
ATC
rabeprazole; oral
2.9
16.5
108
406
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
3.9
16.5
70
191
SPAT1215
SPAT
Assessment of need for medical rehabilitation
4.3
16.5
61
147
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
4.3
16.4
62
152
M46.1
ICD-10 Finland
Sacroiliitis, not elsewhere classified
40.8
16.4
20
5
K07.60
ICD-10 Finland
Snapping jaw
4.1
16.3
64
163
N02AB03
ATC
fentanyl; nasal, sublingual, transdermal
4.7
16.2
55
121
A06AD11
ATC
lactulose; oral
2.6
16.2
123
505
N05BA01
ATC
diazepam; systemic, rectal
2.5
16.2
135
585
A06AC01
ATC
ispaghula (psylla seeds); oral
2.0
16.1
234
1309
M96.0
ICD-10 Finland
Pseudarthrosis after fusion or arthrodesis
48.3
16.1
19
*
L17
ICPC
Foot/toe symptom/complaint
2.0
16.0
237
1334
SAA03
NOMESCO Finland
Extended examination of mouth
1.8
15.9
402
2732
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.9
15.8
267
1579
N06AX03
ATC
mianserin; oral
4.1
15.8
62
158
NA3SA
NOMESCO Finland
Lumbar spine X-ray examination in standing position
61.0
15.8
18
*
G55.1
ICD-10 Finland
Nerve root and plexus compressions in intervertebral disc disorders
33.9
15.8
20
6
SPAT1212
SPAT
Extensive examination of musculoskeletal system
3.1
15.7
89
304
M01AH03
ATC
valdecoxib; oral
3.2
15.7
83
271
72880
ICD-8 Finland
Vertebrogenic pain syndrome, Radicula syndrome of lower limbs
+∞
15.7
15
*
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
3.3
15.6
79
250
R03BA02
ATC
budesonide; inhalant
2.1
15.5
191
996
N04BC05
ATC
pramipexole; oral
3.3
15.5
79
251
SPAT1312
SPAT
General health counselling
1.8
15.3
306
1919
203
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
2.1
15.2
192
1013
R52.9
ICD-10 Finland
Pain, unspecified
3.0
15.2
89
312
ZSN00
NOMESCO Finland
Procedure related to previous procedure classified in chapter N
18.1
15.2
23
13
M01AB01
ATC
indometacin; systemic, rectal
3.2
15.1
83
278
UKC02
NOMESCO Finland
Cystoscopy
2.4
15.1
141
647
N02CC01
ATC
sumatriptan; nasal, systemic, rectal
2.3
15.0
155
748
SPAT1156
SPAT
Guidance concerning treatment of rash and skin
2.4
14.8
130
579
M75.0
ICD-10 Finland
Adhesive capsulitis of shoulder
3.3
14.8
76
243
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.4
14.7
129
574
JN3BD
NOMESCO Finland
Extensive abdominal CT
2.5
14.7
118
501
J01FA06
ATC
roxithromycin; oral
1.7
14.7
410
2856
ND2DA
NOMESCO Finland
Bilateral hand X-ray examination
6.2
14.6
39
65
ACC51
NOMESCO Finland
Release of median nerve
2.9
14.6
92
336
NA2CG
NOMESCO Finland
Thoracal spine extensive MRI examination with high intensity magnet
14.4
14.6
24
17
S46.0
ICD-10 Finland
Injury of muscle(s) and tendon(s) of the rotator cuff of shoulder
2.8
14.6
94
351
NA6CG
NOMESCO Finland
Sacro-iliac joint extensive MRI examination with high intensity magnet
152.0
14.5
15
*
SPAT1254
SPAT
Administration of medicine
2.4
14.5
130
585
A02BA02
ATC
ranitidine; systemic
2.1
14.5
182
955
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
6.7
14.4
36
55
J01MA02
ATC
ciprofloxacin; systemic
1.7
14.3
362
2440
C07AB02
ATC
metoprolol; systemic
2.1
14.3
175
909
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
14.3
167
851
NA6BG
NOMESCO Finland
Sacro-iliac joint MRI examination with high intensity magnet
19.4
14.3
21
11
NGB20
NOMESCO Finland
Primary total prosthetic replacement of knee joint without patellar part
2.6
14.2
105
425
SPAT1301
SPAT
No procedures
1.8
14.2
282
1761
NE1CG
NOMESCO Finland
Pelvic, hip and femur extensive MRI examination with high intensity magnet
6.3
14.0
37
61
SPAT1211
SPAT
Application of soft bandage
2.7
13.9
96
371
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
5.3
13.9
42
82
NB1BA
NOMESCO Finland
Shoulder extensive X-ray examination without contrast
4.9
13.9
45
95
NBG10
NOMESCO Finland
Acromioplastia
6.1
13.9
37
62
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
2.3
13.9
133
617
XX9AW
NOMESCO Finland
Production of copy from X-ray picture
4.6
13.8
48
109
E66.01
ICD-10 Finland
Obesity due to excess calories
2.8
13.8
93
357
R07.3
ICD-10 Finland
Other chest pain
2.8
13.8
92
350
NBL00
NOMESCO Finland
Suture or reinsertation of rotator cuff of shoulder
3.4
13.7
67
207
M01AC01
ATC
piroxicam; systemic, rectal
2.3
13.6
139
665
NA3BA
NOMESCO Finland
Lumbar spine extensive X-ray examination without contrast
76.1
13.6
15
*
G99.2*M47.1
ICD-10 Finland
Spondylogenic compression of spinal cord
+∞
13.6
13
*
9212
FHL
Other posterior root decompression surgery (eg laminectomy, Gill)
+∞
13.6
13
*
M53.3
ICD-10 Finland
Sacrococcygeal disorders, not elsewhere classified
16.4
13.5
21
13
ABC99
NOMESCO Finland
Other decompressive operation on spinal cord or nerve root
141.8
13.5
14
*
SGA01
NOMESCO Finland
Tooth opening as first aid
2.1
13.5
175
930
SPAT1222
SPAT
Counselling/guidance promoting independent living
2.3
13.5
136
649
K30
ICD-10 Finland
Functional dyspepsia
2.4
13.4
115
504
R20.2
ICD-10 Finland
Paraesthesia of skin
3.2
13.4
71
233
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
2.1
13.3
170
899
L16
ICPC
Ankle symptom/complaint
2.6
13.2
100
410
M77.1
ICD-10 Finland
Lateral epicondylitis
2.9
13.2
82
299
F32.11
ICD-10 Finland
Moderate depressive episode with somatic syndrome
4.6
13.1
45
101
J37.0
ICD-10 Finland
Chronic laryngitis
4.8
13.1
43
92
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
2.9
13.0
83
305
G43.0
ICD-10 Finland
Migraine without aura [common migraine]
3.3
13.0
65
204
78559
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Colica abdominalis NUD
4.1
13.0
50
126
R05FB02
ATC
cough suppressants and expectorants
1.7
13.0
372
2586
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.5
12.8
107
464
M03BX01
ATC
baclofen; systemic
7.6
12.7
29
39
M15.9
ICD-10 Finland
Polyarthrosis, unspecified
3.5
12.7
59
175
H02BX01
ATC
methylprednisolone, combinations; systemic
3.8
12.7
54
149
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.7
12.7
91
363
R1220
NOMESCO Finland
Psychological examination of need and possibilities to rehabilitation
15.7
12.6
20
13
SPAT1149
SPAT
Suture or treatment of traumatic wound
2.3
12.6
121
562
N03AF01
ATC
carbamazepine; oral, rectal
3.5
12.6
59
176
NA1BA
NOMESCO Finland
Cervical spine extensive X-ray examination without contrast
17.6
12.5
19
11
ABC66
NOMESCO Finland
Decompression of lumbal spinal channel
+∞
12.5
12
*
M48.9
ICD-10 Finland
Spondylopathy, unspecified
+∞
12.5
12
*
72870
ICD-8 Finland
Vertebrogenic pain syndrome, Lumbalgia
+∞
12.5
12
*
NA7BT
NOMESCO Finland
Injection to spinal facet joint with radiological guidance
+∞
12.5
12
*
7228C
ICD-9 Finland
Intervertebral disk disorders, Postlaminectomy syndrome[SYNDROMA LUMBOSACRALE POSTLAMINECTOMIAM]
+∞
12.5
12
*
7225B
ICD-9 Finland
Intervertebral disk disorders, Degeneration of thoracic or lumbar intervertebral disk[DEGEN DISCI INTERVERT THORAC SEU LUMBOSACR CUM INST]
+∞
12.5
12
*
NB1BG
NOMESCO Finland
Shoulder and humerus MRI examination with high intensity magnet
5.5
12.5
36
67
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.5
12.5
96
399
M70.7
ICD-10 Finland
Other bursitis of hip
5.0
12.4
39
80
N05BA04
ATC
oxazepam; oral
1.8
12.4
229
1384
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.4
12.4
111
497
A07EC01
ATC
sulfasalazine; oral, rectal
2.7
12.4
88
349
E000001
ATC
NA
1.9
12.3
201
1164
A03FA02
ATC
cisapride; oral, rectal
2.9
12.3
76
276
SFA00
NOMESCO Finland
Small filling
2.1
12.3
145
739
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.6
12.3
502
3822
L29
ICPC
Musculoskeletal sympt/complt other
2.8
12.3
79
293
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.5
12.3
97
408
M50.9
ICD-10 Finland
Cervical disc disorder, unspecified
38.0
12.2
15
*
R05DA20
ATC
opium alkaloids and derivatives - combinations
1.8
12.2
248
1548
G43.1
ICD-10 Finland
Migraine with aura [classical migraine]
3.0
12.2
70
242
M79.2
ICD-10 Finland
Neuralgia and neuritis, unspecified
6.2
12.2
32
53
N05CD07
ATC
temazepam; oral
2.3
12.2
113
517
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.9
12.1
214
1272
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
2.4
12.1
105
464
N05CF02
ATC
zolpidem; oral
1.9
12.1
183
1030
WZA00
NOMESCO Finland
Short statement of of health and health related matters
3.0
12.0
70
245
Z00.0
ICD-10 Finland
General medical examination
2.0
12.0
168
917
P01BA02
ATC
hydroxychloroquine; oral
2.5
12.0
95
400
M15.0
ICD-10 Finland
Primary generalized (osteo)arthrosis
5.1
11.9
37
75
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
2.6
11.9
88
355
J02AC01
ATC
fluconazole; systemic
1.6
11.9
409
2966
S29
ICPC
Skin symptom/complaint other
2.0
11.9
154
815
SHA03
NOMESCO Finland
Correction of physiology of bite - demanding therapy visit
4.1
11.9
46
117
L84
ICPC
Back syndrome without radiat pain
4.0
11.9
47
122
NBA30
NOMESCO Finland
Exploration of joint of shoulder or upper arm, arthroscopic
4.9
11.9
38
80
G43.9
ICD-10 Finland
Migraine, unspecified
3.3
11.8
60
191
M16.0
ICD-10 Finland
Primary coxarthrosis, bilateral
3.1
11.8
64
214
SFA30
NOMESCO Finland
Filling on tree or more surfaces of tooth
1.6
11.8
420
3076
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
3.2
11.8
62
203
WX722
NOMESCO Finland
PEEP
3.4
11.8
56
170
R03DC03
ATC
montelukast; oral
2.0
11.7
161
874
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.0
11.7
151
798
AEA50
NOMESCO Finland
Adjustment of implanted neurostimulator
30.4
11.7
15
5
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
2.4
11.6
104
466
M23.9
ICD-10 Finland
Internal derangement of knee, unspecified
2.5
11.6
95
405
R05
ICD-10 Finland
Cough
1.9
11.6
185
1062
NF1DA
NOMESCO Finland
X-ray of hips
5.4
11.6
34
65
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
2.2
11.5
123
600
M17.9
ICD-10 Finland
Gonarthrosis, unspecified
2.3
11.5
113
530
J01CA04
ATC
amoxicillin; systemic
1.7
11.5
788
6801
9183
FHL
Posterolateral spondylodesis
+∞
11.5
11
*
NAG99
NOMESCO Finland
Other excision, reconstruction or fusion of joints of spine, unspecified
+∞
11.5
11
*
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
2.3
11.5
113
531
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
3.1
11.5
62
207
AWE00
NOMESCO Finland
Reoperation for deep heamorrhage in surgery of the nervous system
121.3
11.4
12
*
WX308
NOMESCO Finland
Sacral anesthesy
121.3
11.4
12
*
K02.1
ICD-10 Finland
Caries of dentine
1.6
11.4
550
4333
EBA05
NOMESCO Finland
Complicated extraction of tooth
1.9
11.4
200
1183
C07AA05
ATC
propranolol; systemic
1.9
11.4
195
1143
NH3BA
NOMESCO Finland
Foot and toes extensive X-ray examination
3.6
11.4
50
142
XQ800
NOMESCO Finland
Prick test
2.6
11.4
83
334
SPAT1310
SPAT
Counselling related to known health issue
1.7
11.4
277
1821
G62.9
ICD-10 Finland
Polyneuropathy, unspecified
5.7
11.4
32
58
UJD02
NOMESCO Finland
Gastroscopy
3.5
11.4
52
153
NGD05
NOMESCO Finland
Partial excision of meniscus of knee, arthroscopic
2.1
11.3
128
640
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.6
11.3
449
3367
NA2AD
NOMESCO Finland
Thoracic spine CT examination
35.4
11.3
14
*
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.1
11.2
125
622
R03AC03
ATC
terbutaline; inhalant
2.1
11.2
141
739
N06AX12
ATC
bupropion; oral
2.8
11.1
70
258
E0000UV
ATC
NA
1.6
11.1
372
2668
EBA00
NOMESCO Finland
Extraction of tooth
1.7
11.1
302
2050
M19.9
ICD-10 Finland
Arthrosis, unspecified
3.9
11.1
45
120
L14
ICPC
Leg/thigh symptom/complaint
2.7
11.0
76
296
R03BA05
ATC
fluticasone; inhalant
1.9
11.0
175
1003
M19.8
ICD-10 Finland
Other specified arthrosis
3.9
11.0
44
116
Z02.7
ICD-10 Finland
Issue of medical certificate
2.8
11.0
69
255
F32.00
ICD-10 Finland
Mild depressive episode without somatic syndrome
3.6
10.9
49
142
Q79.6
ICD-10 Finland
Ehlers-Danlos syndrome
43.8
10.9
13
*
J01EA01
ATC
trimethoprim; systemic
1.8
10.9
232
1462
L11
ICPC
Wrist symptom/complaint
2.5
10.9
83
343
SPAT1104
SPAT
Monitoring of emergency patient
2.8
10.8
71
268
KMAK
NOMESCO Finland
NA
1.6
10.8
520
4072
J01MA12
ATC
levofloxacin; systemic
1.9
10.8
168
954
SHA01
NOMESCO Finland
Correction of physiology of bite - simple therapy visit
2.1
10.7
121
603
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.6
10.7
322
2241
M41.9
ICD-10 Finland
Scoliosis, unspecified
21.7
10.7
15
7
ZXD05
NOMESCO Finland
Urgent procedure
1.7
10.6
285
1924
L12
ICPC
Hand/finger symptom/complaint
2.0
10.5
134
703
M01AE52
ATC
naproxen and esomeprazole; oral
3.7
10.5
45
126
SPAT1249
SPAT
Treatment-related counselling outside office
1.6
10.4
359
2582
NA3CM
NOMESCO Finland
Lumbar spine extensive MRI examination with 3 Tesla magnet
111.1
10.4
11
*
7242A
ICD-9 Finland
Other and unspecified disorders of back, Lumbago
+∞
10.4
10
*
72510
ICD-8 Finland
Displacement of intervertebral disk, Lumbalis cum prolapsu disci
+∞
10.4
10
*
7221A
ICD-9 Finland
Intervertebral disk disorders, Displacement of thoracic or lumbar intervertebral disk without myelopathy
+∞
10.4
10
*
TAD08
NOMESCO Finland
Sympathetic block on sacral Level
+∞
10.4
10
*
AB5BT
NOMESCO Finland
Blockage of nerv root with X-ray guidance
+∞
10.4
10
*
ZXE30
NOMESCO Finland
More than five and less than seven hours
2.9
10.4
62
222
ZSA00
NOMESCO Finland
Procedure related to previous procedure classified in chapter A
19.0
10.3
15
8
NG2AA
NOMESCO Finland
Patella X-ray examination
4.3
10.2
37
89
M76.8
ICD-10 Finland
Other enthesopathies of lower limb, excluding foot
7.6
10.2
23
31
T88.7
ICD-10 Finland
Unspecified adverse effect of drug or medicament
6.3
10.2
26
42
FN1AD
NOMESCO Finland
CT of coronary arteries
6.0
10.2
27
46
R06AX22
ATC
ebastine; oral
1.8
10.1
175
1031
G04BD12
ATC
mirabegron; oral
2.4
10.1
89
396
UJF30
NOMESCO Finland
Ileoscopy through colon
2.3
10.1
96
442
R13
ICD-10 Finland
Dysphagia
2.8
10.0
64
239
WX882
NOMESCO Finland
High dependency care
4.2
10.0
37
91
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
2.0
10.0
138
748
XX2BT
NOMESCO Finland
Other injection with X-ray guidance
40.5
10.0
12
*
Z03.8
ICD-10 Finland
Observation for other suspected diseases and conditions
3.4
10.0
48
148
XX1VW
NOMESCO Finland
Written report from radiologist
12.3
9.9
17
14
G43.3
ICD-10 Finland
Complicated migraine
6.0
9.9
26
44
S13.4
ICD-10 Finland
Sprain and strain of cervical spine
3.7
9.8
41
113
G56.2
ICD-10 Finland
Lesion of ulnar nerve
4.0
9.8
38
98
N06AA12
ATC
doxepin; systemic
3.0
9.7
56
195
R32
ICD-10 Finland
Unspecified urinary incontinence
4.2
9.7
36
89
C05AA08
ATC
fluocortolone; rectal, topical
1.9
9.7
147
824
R51.81
ICD-10 Finland
Facial pain NOS
4.8
9.7
31
66
L83
ICPC
Neck syndrome
13.5
9.7
16
12
H02AB07
ATC
prednisone; oral
1.9
9.7
140
774
J01FA09
ATC
clarithromycin; systemic
1.6
9.7
304
2131
M47.81
ICD-10 Finland
Other spondylosis, occipito-atlanto-axial region
55.5
9.7
11
*
T84.0
ICD-10 Finland
Mechanical complication of internal joint prosthesis
4.4
9.7
34
80
D82
ICPC
Teeth/gum disease
1.6
9.6
337
2425
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.7
9.6
216
1382
J01FA10
ATC
azithromycin; systemic
1.5
9.6
566
4594
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.8
9.5
181
1096
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.6
9.5
369
2723
S01GX01
ATC
cromoglicic acid; ophthalmic
1.7
9.5
201
1260
M02AA15
ATC
diclofenac; topical (antiinflammatory prep., non-steroids for topical use)
2.4
9.4
80
351
ABC60
NOMESCO Finland
Decompression of cervical spinal cord
100.9
9.4
10
*
NA7FT
NOMESCO Finland
Labeling lesion in spinal area with X-ray guidance
100.9
9.4
10
*
M47.8
ICD-10 Finland
Other spondylosis
+∞
9.4
9
*
NAG67
NOMESCO Finland
Posterior interbody fusion of lumbar spine, more than 2 vertebrae
+∞
9.4
9
*
NAG60
NOMESCO Finland
Anterior fusion of lumbar spine with fixation
+∞
9.4
9
*
AEA24
NOMESCO Finland
Removal of spinal stimulation elecrode
21.9
9.4
13
6
M25.2
ICD-10 Finland
Flail joint
7.0
9.3
22
32
XQ802
NOMESCO Finland
Epicutan test
3.0
9.3
53
182
R35
ICD-10 Finland
Polyuria
2.8
9.3
58
212
A28
ICPC
Limited function/disability NOS
2.1
9.3
107
538
A01AB09
ATC
miconazole; local oral
2.3
9.3
86
391
Z3226
NOMESCO Finland
Physiotherapist
1.8
9.3
168
1003
F34.1
ICD-10 Finland
Dysthymia
3.3
9.3
45
140
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.9
9.2
54
192
NGF25
NOMESCO Finland
Operation for osteochondritis of knee, arthroscopic
2.5
9.1
74
314
R02
ICPC
Shortness of breath/dyspnoea
2.2
9.1
95
458
TAB00
NOMESCO Finland
Lumbar puncture
3.1
9.1
48
159
M22.4
ICD-10 Finland
Chondromalacia patellae
3.4
9.1
42
126
-
ICD-10 Finland
NA
4.5
9.1
31
71
M89.0
ICD-10 Finland
Algoneurodystrophy
11.6
9.1
16
14
SPAT1295
SPAT
Other function in accordance with physical therapy nomenclature
3.0
9.1
52
181
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
3.1
9.0
47
154
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.5
9.0
395
2983
ZXE20
NOMESCO Finland
More than three and less than five hours
1.9
9.0
131
723
S06.0
ICD-10 Finland
Concussion
2.3
9.0
87
405
M51
ICD-10 Finland
Other intervertebral disc disorders
18.8
8.9
13
7
P76
ICPC
Depressive disorder
2.7
8.9
61
238
ZXD10
NOMESCO Finland
Scheduled procedure
1.5
8.9
354
2615
C03CA01
ATC
furosemide; systemic
1.7
8.9
190
1193
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
1.8
8.9
166
999
I10
ICD-10 Finland
Essential (primary) hypertension
1.5
8.9
488
3875
M01AC02
ATC
tenoxicam; systemic, rectal
2.9
8.8
51
179
F51.0
ICD-10 Finland
Nonorganic insomnia
2.0
8.8
118
634
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.3
8.8
78
350
ACC53
NOMESCO Finland
Release of ulnar nerve
7.3
8.8
20
28
SPAT1226
SPAT
Implementation of occupational therapy rehabilitation plan
4.6
8.7
29
65
R05FA02
ATC
opium derivatives and expectorants; systemic
1.5
8.7
377
2837
M76.6
ICD-10 Finland
Achilles tendinitis
3.9
8.7
34
89
R06AX27
ATC
desloratadine; oral
1.6
8.7
258
1775
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.4
8.7
72
313
K07.61
ICD-10 Finland
Cracking jaw joint
5.3
8.6
25
48
R4110
NOMESCO Finland
Physiotherapy
1.6
8.6
237
1595
M15.8
ICD-10 Finland
Other polyarthrosis
5.9
8.6
23
40
B01AB05
ATC
enoxaparin; parenteral
1.6
8.6
267
1857
SPAT1097
SPAT
Recording of ECG
1.9
8.6
126
699
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.2
8.6
44
143
T81.0
ICD-10 Finland
Haemorrhage and haematoma complicating a procedure, not elsewhere classified
2.6
8.6
62
250
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
2.1
8.5
100
510
M75.8
ICD-10 Finland
Other shoulder lesions
3.7
8.5
36
101
D07AC01
ATC
betamethasone; topical
1.5
8.5
311
2247
G55.2
ICD-10 Finland
Nerve root and plexus compressions in spondylosis
27.8
8.5
11
*
C09CA06
ATC
candesartan; oral
1.7
8.5
201
1297
ZXA00
NOMESCO Finland
Right side
1.6
8.5
227
1516
K29
ICPC
Cardiovascular sympt/complt other
3.2
8.5
43
139
A07AA02
ATC
nystatin; oral
2.6
8.5
59
234
SPAT1260
SPAT
Consultation of another employee
1.8
8.4
154
920
NFB30
NOMESCO Finland
Primary total prosthetic replacement of hip joint not using cement
2.6
8.4
61
246
NA3BM
NOMESCO Finland
Lumbar spine MRI examination with 3 Tesla magnet
90.8
8.4
9
*
M46.4
ICD-10 Finland
Discitis, unspecified
90.8
8.4
9
*
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.3
8.4
76
346
EB1SA
NOMESCO Finland
Dental X-ray, bite-wing X-ray on one side of the mouth
1.5
8.4
479
3820
NAG65
NOMESCO Finland
Anterior and posterior fusion of lumbar spine
+∞
8.3
8
*
7231A
ICD-9 Finland
Other disorders of cervical region, Cervicalgia
+∞
8.3
8
*
G99.2*M50.0
ICD-10 Finland
Cervical disc disorder with myelopathy
+∞
8.3
8
*
K04.0
ICD-10 Finland
Pulpitis
2.1
8.3
100
511
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.6
8.3
264
1841
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.8
8.3
156
939
M23.8
ICD-10 Finland
Other internal derangements of knee
3.1
8.3
44
147
S83.6
ICD-10 Finland
Sprain and strain of other and unspecified parts of knee
2.8
8.3
53
199
F41.1
ICD-10 Finland
Generalized anxiety disorder
3.0
8.3
45
153
SPAT1221
SPAT
Guidance concerning rehabilitation services and livelihood
5.0
8.2
25
51
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.6
8.2
212
1404
R03BB04
ATC
tiotropium bromide; inhalant
2.2
8.2
82
390
G03DC02
ATC
norethisterone; oral
1.9
8.2
119
659
M01AE51
ATC
ibuprofen, combinations; systemic
5.4
8.2
23
43
M75.9
ICD-10 Finland
Shoulder lesion, unspecified
3.0
8.1
46
158
R96
ICPC
Asthma
2.2
8.1
78
362
N05BA02
ATC
chlordiazepoxide; systemic
4.5
8.1
27
61
XKD00
NOMESCO Finland
Uroflowmetry
2.0
8.1
101
528
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
1.6
8.1
252
1747
AEA20
NOMESCO Finland
Removal of impulse generator of stimulation device in the nervous system
33.6
8.1
10
*
TAC00
NOMESCO Finland
Peripheral nerve block
17.3
8.1
12
7
N05BA12
ATC
alprazolam; oral
2.0
8.1
103
543
R06AX13
ATC
loratadine; oral
1.8
8.1
151
909
L20.9
ICD-10 Finland
Atopic dermatitis, unspecified
3.2
8.1
41
133
L60.0
ICD-10 Finland
Ingrowing nail
3.2
8.1
41
133
NB1AE
NOMESCO Finland
Shoulder ultrasound examination
5.1
8.1
24
48
N02CC07
ATC
frovatriptan; oral
2.8
8.0
51
190
G04BD04
ATC
oxybutynin; oral, transdermal
3.0
8.0
46
160
M53.8
ICD-10 Finland
Other specified dorsopathies
10.1
8.0
15
15
D07AD01
ATC
clobetasol; topical
1.8
8.0
152
917
NK6PA
NOMESCO Finland
Measurement of bone density from one location with X-ray
22.2
8.0
11
5
7177A
ICD-9 Finland
Internal derangement of knee, Chondromalacia of patella
5.6
8.0
22
40
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
3.7
8.0
33
91
R60.0
ICD-10 Finland
Localized oedema
2.1
8.0
94
480
NBF25
NOMESCO Finland
Operation for humeroscapular osteochondritis, arthroscopic
4.4
8.0
27
62
J45.0
ICD-10 Finland
Predominantly allergic asthma
2.3
7.9
75
347
J40
ICD-10 Finland
Bronchitis, not specified as acute or chronic
3.7
7.9
33
92
KC1EE
NOMESCO Finland
Ultrasound measurement of residual urine
2.1
7.9
89
447
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
2.2
7.9
77
362
M16.9
ICD-10 Finland
Coxarthrosis, unspecified
3.0
7.9
43
147
R53
ICD-10 Finland
Malaise and fatigue
1.7
7.9
162
1006
1220
FHL
Arthroscopy
2.9
7.8
45
158
NGA30
NOMESCO Finland
Exploration of knee joint, arthroscopic
2.7
7.8
53
205
R5599
NOMESCO Finland
Other rehabilitation service
4.5
7.8
26
59
N06AB10
ATC
escitalopram; oral
1.7
7.8
178
1138
JFA15
NOMESCO Finland
Endoscopic polypectomy in colon
2.9
7.8
45
159
M75.2
ICD-10 Finland
Bicipital tendinitis
4.3
7.7
27
64
JAH01
NOMESCO Finland
Laparoscopy
2.6
7.7
53
208
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.7
7.7
157
969
C03EA01
ATC
hydrochlorothiazide and potassium-sparing agents; oral
1.8
7.7
126
728
TQW40
NOMESCO Finland
Remowal of suture of skin
2.2
7.7
73
338
N06AB05
ATC
paroxetine; oral
2.4
7.7
65
285
CK2S4
NOMESCO Finland
Plain photography of ocular fundus
2.5
7.6
59
246
J01MA06
ATC
norfloxacin; oral
1.8
7.6
129
752
M01AG02
ATC
tolfenamic acid; oral, rectal
1.7
7.6
163
1023
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.3
7.5
67
301
TNX00
NOMESCO Finland
Puncture and needle biopsy of soft tissue, unspecified region
4.7
7.5
24
52
A03CA02
ATC
clidinium and psycholeptics; oral
2.6
7.5
53
213
NGB40
NOMESCO Finland
Primary total prosthetic replacement of knee joint with patellar part - sliding prosthesis
4.5
7.5
25
57
Z03.80
ICD-10 Finland
Observation for other suspected diseases and conditions
3.1
7.5
38
124
E66.8
ICD-10 Finland
Other obesity
2.5
7.4
55
225
G04BD08
ATC
solifenacin; oral
2.5
7.4
58
244
G44.8
ICD-10 Finland
Other specified headache syndromes
6.5
7.4
18
28
Z98.1
ICD-10 Finland
Arthrodesis status
80.6
7.4
8
*
XG410
NOMESCO Finland
Flow-volume spirometry
3.0
7.4
40
136
SPAT1083
SPAT
Initiation and monitoring of IV fluid therapy
2.8
7.4
44
159
TAKUU
NOMESCO Finland
NA
7.7
7.4
16
21
SPAT1203
SPAT
Injection therapy, other than intramuscular or subcutaneous
3.0
7.4
42
145
M47
ICD-10 Finland
Spondylosis
13.5
7.4
12
9
M71.2
ICD-10 Finland
Synovial cyst of popliteal space [Baker]
3.4
7.4
33
98
XG474
NOMESCO Finland
Exhalation nntrogen oxide
3.4
7.4
33
98
C01CA24
ATC
epinephrine; parenteral
2.4
7.4
60
257
H01
ICPC
Ear pain/earache
2.0
7.4
95
502
NDG60
NOMESCO Finland
Arthroplasty of first CMC joint
4.8
7.4
23
49
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.0
7.3
93
489
N03A
ATC
ANTIEPILEPTICS
+∞
7.3
7
*
M43.2
ICD-10 Finland
Other fusion of spine
+∞
7.3
7
*
M50.8
ICD-10 Finland
Other cervical disc disorders
+∞
7.3
7
*
NAG42
NOMESCO Finland
Posterior fusion of cervical spine with or without fixation
+∞
7.3
7
*
K08.80
ICD-10 Finland
Toothache NOS
2.2
7.3
75
359
J35.0
ICD-10 Finland
Chronic tonsillitis
2.6
7.3
51
203
PA7BD
NOMESCO Finland
CT angiography of neck and brain
4.5
7.3
24
54
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
2.9
7.3
42
148
R03BA01
ATC
beclometasone; inhalant
1.8
7.3
122
709
R03BA08
ATC
ciclesonide; inhalant
2.1
7.2
77
376
M19.1
ICD-10 Finland
Post-traumatic arthrosis of other joints
3.6
7.2
30
84
J34.2
ICD-10 Finland
Deviated nasal septum
2.6
7.2
51
205
R51
ICD-10 Finland
Headache
2.8
7.2
44
163
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.9
7.2
111
629
D07AA02
ATC
hydrocortisone; topical
1.8
7.2
116
666
M13.9
ICD-10 Finland
Arthritis, unspecified
2.3
7.1
65
297
R03AK07
ATC
formoterol and budesonide; inhalant
1.6
7.1
182
1199
DM1AA
NOMESCO Finland
Paranasal sinuses X-ray examination without contrast
3.0
7.1
38
129
50099
ICD-8 Finland
Hypertrophy of tonsils and adenoids
1.8
7.1
112
638
NBG00
NOMESCO Finland
Plastic operation on acromioclavicular joint
5.7
7.1
19
34
R05DA01
ATC
ethylmorphine; oral
2.0
7.1
83
424
ZXE10
NOMESCO Finland
More than one and less than three hours
1.5
7.1
311
2324
J01MA01
ATC
ofloxacin; systemic
2.1
7.0
78
387
N06AB03
ATC
fluoxetine; oral
1.8
7.0
113
647
SGC00
NOMESCO Finland
Local medication of root channels of tooth
1.9
7.0
109
617
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.4
7.0
55
233
SPAT1305
SPAT
Counselling and guidance related to physical exercise
2.1
7.0
78
391
P03
ICPC
Feeling depressed
2.1
6.9
73
356
H66.0
ICD-10 Finland
Acute suppurative otitis media
2.5
6.9
53
223
H81.1
ICD-10 Finland
Benign paroxysmal vertigo
2.0
6.9
80
407
Z01.0
ICD-10 Finland
Examination of eyes and vision
1.7
6.9
136
832
M01AB16
ATC
aceclofenac; oral
3.2
6.9
34
109
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
4.0
6.9
26
67
A06AC51
ATC
ispaghula, combinations; systemic
2.6
6.9
48
190
SAA04
NOMESCO Finland
Special inverstigation of mouth
2.5
6.9
54
227
L72.1
ICD-10 Finland
Trichilemmal cyst
2.3
6.9
63
289
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
1.9
6.9
108
613
M75.5
ICD-10 Finland
Bursitis of shoulder
4.2
6.8
24
58
R05
ICPC
Cough
1.6
6.8
185
1238
G56.4
ICD-10 Finland
Causalgia
11.0
6.8
12
11
SPAT1043
SPAT
Audiometry
2.1
6.8
76
378
R03AC13
ATC
formoterol; inhalant
2.6
6.8
48
193
L04AB01
ATC
etanercept; parenteral
5.7
6.8
18
32
N01
ICPC
Headache
2.1
6.8
76
380
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
2.9
6.8
39
138
N07BC02
ATC
methadone; systemic
16.8
6.7
10
6
SDE02
NOMESCO Finland
Periodontal treatment by dental hygienist
1.5
6.7
227
1597
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.3
6.7
59
263
K43.9
ICD-10 Finland
Other and unspecified ventral hernia without obstruction or gangrene
2.6
6.7
45
176
M16
ICD-10 Finland
Coxarthrosis [arthrosis of hip]
2.8
6.7
40
146
FM1CR
NOMESCO Finland
Heart perfusion PET with TT
22.7
6.7
9
*
G83.4
ICD-10 Finland
Cauda equina syndrome
22.7
6.7
9
*
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.5
6.7
246
1766
S93.4
ICD-10 Finland
Sprain and strain of ankle
1.9
6.7
92
500
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
3.2
6.7
32
101
NF1BA
NOMESCO Finland
Hip extensive X-ray examination
3.5
6.6
29
85
SPAT1202
SPAT
Intra-articular injection
3.3
6.6
31
96
H25.8
ICD-10 Finland
Other senile cataract
2.1
6.6
75
377
A03FA01
ATC
metoclopramide; systemic, rectal
1.6
6.6
190
1288
R15
ICD-10 Finland
Faecal incontinence
3.8
6.6
26
70
G03CA03
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
1.4
6.6
401
3189
XF402
NOMESCO Finland
ECG with work load test
1.9
6.5
89
482
78551
ICD-8 Finland
Symptoms referable to abdomen and lower gastro-intestinal tract, Symptomata abdominalis acuta NUD
3.2
6.5
32
103
NG1BG
NOMESCO Finland
Knee and lower leg MRI examination with high intensity magnet
2.8
6.5
39
143
C10AA01
ATC
simvastatin; oral
1.4
6.5
332
2551
A04
ICPC
Weakness/tiredness general
1.9
6.5
96
534
M24.2
ICD-10 Finland
Disorder of ligament
4.5
6.5
21
47
NA7CG
NOMESCO Finland
Spine and spinal cord extensive MRI examination with high intensity magnet
6.2
6.5
16
26
H53.1
ICD-10 Finland
Subjective visual disturbances
2.4
6.4
53
232
D07BC01
ATC
betamethasone and antiseptics; topical
1.8
6.4
112
660
H60.9
ICD-10 Finland
Otitis externa, unspecified
2.3
6.4
57
256
M41.5
ICD-10 Finland
Other secondary scoliosis
70.3
6.4
7
*
L04AA13
ATC
leflunomide; oral
3.6
6.4
27
77
K29.3
ICD-10 Finland
Chronic superficial gastritis
3.3
6.4
30
93
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
2.1
6.4
67
326
SPAT1099
SPAT
Measurement of blood pressure with Doppler ultrasound device
3.7
6.4
26
72
JN3AD
NOMESCO Finland
Abdominal CT examination
2.1
6.4
72
363
SGB10
NOMESCO Finland
Fiiling of rooth of tooth with one root channel
1.8
6.4
115
685
SGA02
NOMESCO Finland
Opening and dilatation of root canal of tooth
1.7
6.4
120
725
H03AA01
ATC
levothyroxine sodium; systemic
1.5
6.4
215
1512
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.5
6.4
204
1417
SPAT1255
SPAT
Intravenous administration of medicine
2.3
6.4
54
238
N06AX26
ATC
vortioxetine; oral
2.4
6.4
51
218
ZXX03
NOMESCO Finland
Extent of procedure, 3 units
8.2
6.3
13
16
L03.0
ICD-10 Finland
Cellulitis of finger and toe
2.2
6.3
62
294
K10.3
ICD-10 Finland
Alveolitis of jaws
2.7
6.3
39
146
M24.4
ICD-10 Finland
Recurrent dislocation and subluxation of joint
6.0
6.3
16
27
NGF35
NOMESCO Finland
Plastic operation of joint cartilage of knee
2.7
6.3
41
157
-57
ICPC
Physical medicine/rehabilitation
11.1
6.3
11
10
S80.0
ICD-10 Finland
Contusion of knee
2.3
6.3
56
252
C01DA14
ATC
isosorbide mononitrate; oral
2.0
6.3
79
415
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.7
6.3
117
703
H57.1
ICD-10 Finland
Ocular pain
3.1
6.3
32
106
K05.31
ICD-10 Finland
Periodontitis pronounced
1.9
6.3
87
475
J01CE02
ATC
phenoxymethylpenicillin; oral
1.4
6.3
652
5686
ABC50
NOMESCO Finland
Decopression of cervical spinal canal and nerve roots
+∞
6.3
6
*
7240B
ICD-9 Finland
Other and unspecified disorders of back, Spinal stenosis, other than cervical[STENOSIS CANALIS SPINALIS LUMBOSACRALIS]
+∞
6.3
6
*
7225A
ICD-9 Finland
Intervertebral disk disorders, Degeneration of thoracic or lumbar intervertebral disk[DEGENERATIO DISCI INTERVERTEBRALIS THORAC SEU LUMB]
+∞
6.3
6
*
M48
ICD-10 Finland
Other spondylopathies
+∞
6.3
6
*
M43.3
ICD-10 Finland
Recurrent atlantoaxial subluxation with myelopathy
+∞
6.3
6
*
NBL22
NOMESCO Finland
Myotomy, tenotomy or excision of tendon of upper arm
4.4
6.3
21
49
S63.3
ICD-10 Finland
Traumatic rupture of ligament of wrist and carpus
4.4
6.3
21
49
M17
ICD-10 Finland
Gonarthrosis [arthrosis of knee]
1.9
6.2
89
491
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
3.1
6.2
31
101
I49.9
ICD-10 Finland
Cardiac arrhythmia, unspecified
1.8
6.2
96
544
J31.0
ICD-10 Finland
Chronic rhinitis
2.1
6.2
68
339
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
3.0
6.2
33
113
SPAT1296
SPAT
Other function in accordance with occupational therapy nomenclature
5.4
6.2
17
32
-1
NOMESCO Finland
NA
1.5
6.2
288
2172
SPAT1009
SPAT
Measurement of intraocular pressure
5.8
6.2
16
28
N92.1
ICD-10 Finland
Excessive and frequent menstruation with irregular cycle
2.2
6.1
56
258
M01AE11
ATC
tiaprofenic acid; oral, rectal
2.7
6.1
38
143
NHU20
NOMESCO Finland
Removal of internal fixation device from ankle or foot
2.6
6.1
43
171
C10AX09
ATC
ezetimibe; oral
1.9
6.1
87
478
WX404
NOMESCO Finland
Intravenous generell anesthesy
1.6
6.1
187
1286
J01CA08
ATC
pivmecillinam; oral
1.4
6.1
358
2818
6421
FHL
Appendicectomy
2.2
6.1
55
252
D07CC01
ATC
betamethasone and antibiotics; topical
1.7
6.0
118
718
R03AL09
ATC
formoterol, glycopyrronium bromide and beclometasone; inhalant
4.2
6.0
21
51
NG1BA
NOMESCO Finland
Knee extensive X-ray examination
4.2
6.0
21
51
J01MA14
ATC
moxifloxacin; systemic
2.0
6.0
75
393
Mortality – FinRegistry
↥Association
Association between endpoint M13_SPININSTAB and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_SPININSTAB | 0.97 [0.83, 1.14] | 0.708 |
| Birth year | 0.996 [0.99, 1.01] | 0.381 |
During the follow-up period (1.1.1998 — 31.12.2019), 197 out of 3121 females with M13_SPININSTAB died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| M13_SPININSTAB | 0.857 [0.72, 1.02] | 0.087 |
| Birth year | 0.987 [0.98, 1.0] | 0.02 |
During the follow-up period (1.1.1998 — 31.12.2019), 168 out of 2051 males with M13_SPININSTAB died.
Mortality risk
Mortality risk for people of age
years, who have M13_SPININSTAB.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.097% | 0.213% |
| 5 | 0.555% | 1.074% |
| 10 | 1.28% | 2.521% |
| 15 | 2.579% | 4.811% |
| 20 | 4.848% | 8.039% |
Relationships between endpoints
↥Index endpoint: M13_SPININSTAB – Spinal instabilities
GWS hits: 1
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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