Type 1 diabetes, strict definition

T1D_STRICT

type I diabetes mellitus: A chronic condition characterized by minimal or absent production of insulin by the pancreas.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions

not E4_DM2

270311

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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Include endpoints

3176

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T1D_STRICT

Extra metadata

First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 3100 1548 1552
Unadjusted prevalence (%) 1.00 0.89 1.15
Mean age at first event (years) 13.73 13.21 14.26

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 6.04 [3.57, 10.24] 2.3e-11 58
15 years 0.04 6.37 [3.60, 11.28] 2.2e-10 31
5 years - - - -
1 year - - - -

Correlations

Index endpoint: T1D_STRICT – Type 1 diabetes, strict definition
GWS hits: 23

Survival analyses between endpoints

Plot

before Type 1 diabetes, strict definition
after Type 1 diabetes, strict definition

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Drugs most likely to be purchased after Type 1 diabetes, strict definition