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This is a non-core endpoint: only basic statistics are computed.

Carcinoma in situ, eye

Endpoint Browser

CD2_INSITU_EYE_EXALLC

Endpoint definition

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Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

None

-

2. Check conditions

  • not C3_EYE_ADNEXA
-

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 — D09.2&
  • Hospital discharge: ICD-9 — 2340
  • Cause of death: ICD-10 — D09.2&
  • Cause of death: ICD-9 — 2340
  • Cancer registry: Topography ICD-O-3 — C69
  • Cancer registry: Morphology ICD-O-3 — ANY
  • Cancer registry: Behaviour codes — 2

3 out of 7 registries used, show all original rules.

-

4. Check minimum number of events

None

-

5. Include endpoints

None

-

6. Filter based on genotype QC (FinnGen only)

None

-

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF9
Parent code in ICD-10
D09

Case counts by codes

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FinnGen case counts by registry codes:

No upset plot: script not run.

No upset table: script not run.

Summary Statistics

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-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population - - -
Only index persons - - -
Unadjusted period prevalence (%)
Whole population - - -
Only index persons - - -
Median age at first event (years)
Whole population - - -
Only index persons - - -

-FinnGen-

Key figures

All Female Male
Number of individuals 7 - 6
Unadjusted period prevalence (%) 0.00 - 0.00
Median age at first event (years) 63.39 - 64.33

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

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CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

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OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
0
10
0.00
0.23
0.0
5.5
—
—
—
0
0
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0
0
6
0.00
0.00
0.0
6.2
—
—
—
0
0
0
5
0.00
0.00
0.0
4.4
—
14.0
—
0
5
0
7
0.00
0.00
0.0
5.7
—
1.1
—
0
7

Mortality – FinRegistry

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Association

Association between endpoint CD2_INSITU_EYE_EXALLC and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have CD2_INSITU_EYE_EXALLC.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

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Index endpoint: CD2_INSITU_EYE_EXALLC – Carcinoma in situ, eye

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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