Other transitory neonatal electrolyte and metabolic disturbances

P16_OTH_TRANSITO_NEONTAL_ELECTROL_METABOLIC_DISTU

No definition available.

Endpoint definition

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Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — P74 Cause of death: ICD-10 — P74 2 out of 7 registries used, show all original rules.	5
4. Check minimum number of events None	5
5. Include endpoints None	5
6. Filter based on genotype QC (FinnGen only)	5

Control definitions (FinnGen only)

Control exclude: P16_TRANSITO_ENDOCR_METABOLIC_DISORD_SPECIFIC_FETUS_NEWBO

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: P7[0-4]
Name in latin: Aliae perturbationes transitoriae neonatales electrolyticae et metabolicae

NAME	P16_OTH_TRANSITO_NEONTAL_ELECTROL_METABOLIC_DISTU
CONTROL_EXCLUDE	P16_TRANSITO_ENDOCR_METABOLIC_DISORD_SPECIFIC_FETUS_NEWBO
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	P74
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	P74
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

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List of similar endpoints to Other transitory neonatal electrolyte and metabolic disturbances based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

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FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

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-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	925	387	538
Only index persons	410	162	248
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.02
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	-	0.01	0.01
Only index persons	0.00	0.01	0.00

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	5	-	-
Unadjusted period prevalence (%)	0.00	-	-
Median age at first event (years)	5.45	-	-

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

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CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

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(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3021601) Nitrite [Presence] in Urine by Test strip

+∞

1.28

14.2

7.5

—

(3035350) Ketones [Presence] in Urine by Test strip

+∞

1.28

7.4

4.3

—

(3009261) Glucose [Presence] in Urine by Test strip

+∞

1.28

7.4

4.3

—

(3037467) Urinalysis macro (dipstick) panel - Urine

+∞

0.84

18.6

6.2

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

+∞

0.82

14.2

16.6

5.4

3.8

e9/l

—

(3019198) Lymphocytes [#/volume] in Blood

+∞

0.80

11.8

12.9

2.9

3.0

e9/l

—

(3006315) Basophils [#/volume] in Blood

+∞

0.80

11.6

12.8

0.0

e9/l

—

(3001604) Monocytes [#/volume] in Blood

+∞

0.80

11.6

12.8

0.8

0.6

e9/l

—

(3013115) Eosinophils [#/volume] in Blood

+∞

0.51

13.8

0.2

e9/l

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

+∞

0.24

25.0

16.0

47.0

42.8

umol/l

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

0.00

0.24

0.0

2.0

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.0

1.6

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

0.00

0.0

2.7

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

0.00

0.0

5.2

—

(3017732) Neutrophils [#/volume] in Blood

0.00

0.0

1.0

—

4.6

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

0.00

0.0

2.7

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

0.00

0.0

1.6

—

(3026493) Urate [Moles/volume] in Serum or Plasma

0.00

0.0

12.0

—

240.8

—

(3002385) Erythrocyte distribution width [Ratio]

+∞

0.00

70.6

24.1

13.5

13.4

—

(40766189) Gliadin peptide IgG Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.2

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.00

0.0

1.2

—

(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay

0.00

0.0

1.8

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

0.00

0.0

1.7

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

4.5

—

Mortality – FinRegistry

↥

Association

Association between endpoint P16_OTH_TRANSITO_NEONTAL_ELECTROL_METABOLIC_DISTU and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have P16_OTH_TRANSITO_NEONTAL_ELECTROL_METABOLIC_DISTU.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

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Index endpoint: P16_OTH_TRANSITO_NEONTAL_ELECTROL_METABOLIC_DISTU – Other transitory neonatal electrolyte and metabolic disturbances

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Other transitory neonatal electrolyte and metabolic disturbances

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints