This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Lactose intolerance
E4_LACTOSEINT
lactose intolerance: Inability to fully digest and absorb lactose due to limited or no lactase activity in the small intestine. Congenital intolerance is inherited following an autosomal recessive pattern but is rare. It is more often due to a gradual decline of lactase production in adulthood following the ingestion of fewer lactose-containing foods or secondary to an intestinal mucosal brush-border injury. Prevalence is highest among Asians, Native Americans and Africans. Clinical signs include abdominal cramping, bloating, flatulence and diarrhea following the dietary intake of lactose.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
948 |
4. Check minimum number of eventsNone |
948 |
5. Include endpoints |
1238 |
6. Filter based on genotype QC (FinnGen only) |
1238 |
Control definitions (FinnGen only)
- Control exclude
- E4_METABOLIA
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- E70-E90
- Name in latin
- Intolerantia lactosi
Similar endpoints
↥List of similar endpoints to
Lactose intolerance
based on the number of shared cases.
Similar with more cases:
- Metabolic disorders
- Endocrine, nutritional and metabolic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 1238 | 851 | 387 |
| Unadjusted period prevalence (%) | 0.25 | 0.29 | 0.17 |
| Median age at first event (years) | 41.01 | 39.91 | 43.45 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 1105
- Matched controls
- 11049
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E73.9
ICD-10 Finland
Lactose intolerance, unspecified
2148.7
323.0
485
*
2713A
ICD-9 Finland
Disorders of carbohydrate transport and metabolism, Intestinal disaccharidase deficiencies and disaccharide malabsorption[MALABSORPTIO LACTOSI]
+∞
302.4
276
*
E73.8
ICD-10 Finland
Other lactose intolerance
1017.2
254.8
240
*
E73.0
ICD-10 Finland
Congenital lactase deficiency
825.1
79.4
77
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
3.6
75.2
440
1698
R10.4
ICD-10 Finland
Other and unspecified abdominal pain
3.2
71.6
563
2693
UJF32
NOMESCO Finland
Coloscopy
3.6
69.7
394
1460
K58.0
ICD-10 Finland
Irritable bowel syndrome with diarrhoea
7.2
66.8
174
281
A06AC01
ATC
ispaghula (psylla seeds); oral
3.4
59.9
374
1463
E73
ICD-10 Finland
Lactose intolerance
57.6
51.1
60
11
E73.1
ICD-10 Finland
Secondary lactase deficiency
+∞
44.0
42
*
A02BC01
ATC
omeprazole; systemic
2.7
41.6
363
1694
A02BC05
ATC
esomeprazole; systemic
2.4
40.7
492
2744
A02BC02
ATC
pantoprazole; systemic
2.3
36.5
709
4875
K30
ICD-10 Finland
Functional dyspepsia
3.6
33.4
164
508
A02BA02
ATC
ranitidine; systemic
2.8
32.9
254
1079
K90.0
ICD-10 Finland
Coeliac disease
7.0
32.3
82
125
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
4.1
31.2
130
349
R10.3
ICD-10 Finland
Pain localized to other parts of lower abdomen
2.4
30.8
310
1520
R10.1
ICD-10 Finland
Pain localized to upper abdomen
2.7
29.6
228
962
A03CA02
ATC
clidinium and psycholeptics; oral
4.7
28.3
101
233
A02BC03
ATC
lansoprazole; oral
2.2
27.6
342
1840
Z01.8
ICD-10 Finland
Other specified special examinations
2.4
27.2
266
1275
UJD02
NOMESCO Finland
Gastroscopy
5.1
27.1
88
183
J01MA02
ATC
ciprofloxacin; systemic
2.1
26.5
420
2511
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.2
26.4
355
1974
C10AC01
ATC
colestyramine; oral
7.6
26.0
62
86
P01AB01
ATC
metronidazole; oral, rectal
2.0
25.8
457
2849
K59.1
ICD-10 Finland
Functional diarrhoea
4.5
25.2
94
226
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.4
24.6
234
1096
M79.6
ICD-10 Finland
Pain in limb
2.0
24.3
404
2441
K21.9
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
3.2
24.1
135
458
R03AC02
ATC
salbutamol; inhalant
1.9
23.6
604
4282
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
7.1
23.3
58
86
K52.9
ICD-10 Finland
Noninfective gastroenteritis and colitis, unspecified
5.4
23.3
72
142
N03AX16
ATC
pregabalin; oral
2.2
22.8
269
1396
R06.0
ICD-10 Finland
Dyspnoea
2.2
22.6
277
1463
K58.9
ICD-10 Finland
Irritable bowel syndrome without diarrhoea
5.0
22.1
73
155
N02AX02
ATC
tramadol; systemic, rectal
1.9
21.7
440
2838
K52.88
ICD-10 Finland
Other specified noninfective gastroenteritis and colitis
8.0
21.2
48
62
R07.4
ICD-10 Finland
Chest pain, unspecified
2.1
20.7
268
1441
A03FA02
ATC
cisapride; oral, rectal
3.1
20.3
115
393
R01AD09
ATC
mometasone; nasal
1.8
19.7
519
3623
R01AD08
ATC
fluticasone; nasal
2.0
19.7
340
2047
J02AC01
ATC
fluconazole; systemic
1.8
19.5
471
3194
R51.80
ICD-10 Finland
Headache
2.3
19.2
200
971
M54.5
ICD-10 Finland
Low back pain
1.9
19.1
364
2271
K21.0
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
2.8
19.1
127
483
7890A
ICD-9 Finland
Other symptoms involving abdomen and pelvis, Abdominal pain
3.6
18.5
85
247
N06AX21
ATC
duloxetine; oral
2.6
18.0
140
580
GD1AA
NOMESCO Finland
Thorax X-ray examination
1.8
17.8
406
2678
5641A
ICD-9 Finland
Functional digestive disorders, not elsewhere classified, Irritable colon
67.7
17.8
20
*
R53
ICD-10 Finland
Malaise and fatigue
2.1
17.8
235
1268
J01FF01
ATC
clindamycin; systemic
1.9
17.3
288
1697
M01AB05
ATC
diclofenac; systemic, rectal
1.7
17.3
679
5286
K29.3
ICD-10 Finland
Chronic superficial gastritis
5.2
17.2
53
105
H02AB04
ATC
methylprednisolone; systemic
2.3
17.1
180
873
R06AE07
ATC
cetirizine; oral
1.7
16.7
493
3502
A07EC02
ATC
mesalazine; oral, rectal
3.3
16.2
84
269
J01MA12
ATC
levofloxacin; systemic
2.2
16.2
187
947
G47.3
ICD-10 Finland
Sleep apnoea
2.1
16.1
210
1119
J01FA10
ATC
azithromycin; systemic
1.7
16.1
664
5184
UJF30
NOMESCO Finland
Ileoscopy through colon
2.7
16.0
116
464
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
2.3
16.0
152
703
N06AB04
ATC
citalopram; systemic
2.0
15.7
241
1371
5790A
ICD-9 Finland
Intestinal malabsorption, Coeliac disease
86.3
15.6
17
*
D01
ICPC
Abdominal pain/cramps general
2.4
15.3
143
654
M25.5
ICD-10 Finland
Pain in joint
1.8
15.3
309
1936
A02BC04
ATC
rabeprazole; oral
2.7
15.3
108
424
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
1.7
15.3
407
2786
J01DA01
ATC
[U] cefalexin; systemic
1.7
15.2
663
5219
M01AE03
ATC
ketoprofen; systemic, rectal
1.7
14.7
376
2534
N03AX12
ATC
gabapentin; oral
2.2
14.7
164
815
K57.3
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
2.2
14.6
161
796
N05AH04
ATC
quetiapine; oral
2.0
14.5
195
1049
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.7
14.5
101
394
R42
ICD-10 Finland
Dizziness and giddiness
2.0
14.2
216
1221
M79.0
ICD-10 Finland
Rheumatism, unspecified
4.0
14.2
57
149
N06AA09
ATC
amitriptyline; systemic
2.5
14.0
117
506
A06AC51
ATC
ispaghula, combinations; systemic
3.4
13.9
68
209
L03
ICPC
Low back symptom/complaint
1.8
13.6
261
1598
J45.9
ICD-10 Finland
Asthma, unspecified
2.0
13.6
201
1120
J01AA02
ATC
doxycycline; systemic
1.7
13.6
789
6610
C05AA08
ATC
fluocortolone; rectal, topical
2.2
13.5
150
745
M03BX02
ATC
tizanidine; oral
1.6
13.5
635
5026
A07DA03
ATC
loperamide; oral
4.1
13.5
52
131
J06.9
ICD-10 Finland
Acute upper respiratory infection, unspecified
1.6
13.5
518
3888
E87.6
ICD-10 Finland
Hypokalaemia
13.0
13.4
23
18
F32.9
ICD-10 Finland
Depressive episode, unspecified
2.1
13.4
155
782
H02AB06
ATC
prednisolone; systemic
1.6
13.4
465
3395
A07EC01
ATC
sulfasalazine; oral, rectal
2.6
13.3
103
425
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
14.0
13.3
22
16
M51.1
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
2.1
13.2
152
765
C01DA14
ATC
isosorbide mononitrate; oral
2.4
13.2
114
500
J01FA09
ATC
clarithromycin; systemic
1.7
13.1
339
2276
A06AD11
ATC
lactulose; oral
2.2
12.9
144
716
N39.4
ICD-10 Finland
Other specified urinary incontinence
2.7
12.9
92
365
WYA05
NOMESCO Finland
Emergency visit or other similar visit involving procedures
1.6
12.8
515
3894
N02AA59
ATC
codeine, combinations excl. psycholeptics; systemic
1.6
12.7
451
3298
G44.2
ICD-10 Finland
Tension-type headache
2.1
12.7
148
750
A01AB09
ATC
miconazole; local oral
2.5
12.6
102
432
F33.10
ICD-10 Finland
Recurrent depression, moderate episode without somatic syndrome
2.9
12.6
79
290
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
8.4
12.6
27
33
N02BE01
ATC
paracetamol; systemic, rectal
1.7
12.5
871
7571
K44.9
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
2.7
12.5
85
327
J01FA06
ATC
roxithromycin; oral
1.6
12.5
408
2916
1310
FHL
Esophagogastroscopy
24.6
12.5
17
7
XF400
NOMESCO Finland
ECG with 12 standard connections
2.1
12.5
157
822
H04.10
ICD-10 Finland
Dry eye syndrome
2.4
12.4
111
496
N05BA04
ATC
oxazepam; oral
1.8
12.3
262
1654
E78.00
ICD-10 Finland
Familial hypercholesterolaemia
10.7
12.3
23
22
L28
ICPC
Limited function/disability (L)
2.1
12.2
145
738
C01DA08
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
2.0
12.2
170
926
M03BC51
ATC
orphenadrine, combinations; systemic
1.7
12.1
288
1880
M79.7
ICD-10 Finland
Fibromyalgia
3.6
12.0
53
151
L17
ICPC
Foot/toe symptom/complaint
1.7
11.7
258
1641
M79.1
ICD-10 Finland
Myalgia
2.1
11.7
145
752
M03BC01
ATC
orphenadrine (citrate); systemic
1.8
11.5
243
1523
N06AX11
ATC
mirtazapine; oral
1.7
11.5
316
2143
N02AE01
ATC
buprenorphine; parenteral, sublingual, transdermal
2.3
11.5
112
523
J45
ICD-10 Finland
Asthma
2.3
11.5
113
527
1300
FHL
Esophagogastroduodenoscopy (also includes staining)
12.0
11.4
20
17
V700A
ICD-9 Finland
General medical examination, Routine general medical examination at a health care facility
4.6
11.3
38
84
R10.0
ICD-10 Finland
Acute abdomen
3.7
11.3
48
133
L01
ICPC
Neck symptom/complaint
2.0
11.1
155
843
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.1
11.1
127
638
LC2BE
NOMESCO Finland
Transvaginal ultrasound examination of uterus, parametria and lower abdomen
1.7
11.0
299
2016
N05BA01
ATC
diazepam; systemic, rectal
2.0
11.0
142
750
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
11.0
422
3119
R01AD12
ATC
fluticasone furoate; nasal
1.6
10.8
326
2261
J01.0
ICD-10 Finland
Acute maxillary sinusitis
1.7
10.7
245
1570
7879X
ICD-9 Finland
Symptoms involving digestive system, Other symptoms involving digestive system
18.0
10.7
16
9
M54.4
ICD-10 Finland
Lumbago with sciatica
1.9
10.6
171
979
J01EA01
ATC
trimethoprim; systemic
1.7
10.6
268
1772
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.4
10.6
89
386
R01BA52
ATC
pseudoephedrine, combinations; oral
1.6
10.6
301
2053
Z04.8
ICD-10 Finland
Examination and observation for other specified reasons
2.0
10.5
137
725
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
10.5
267
1765
AA1AD
NOMESCO Finland
CT of head and brain
1.8
10.4
188
1118
M01AH05
ATC
etoricoxib; oral
1.5
10.4
563
4484
UKC02
NOMESCO Finland
Cystoscopy
2.0
10.4
132
691
L30.9
ICD-10 Finland
Dermatitis, unspecified
1.9
10.4
174
1010
M03BA52
ATC
carisoprodol, combinations excl. psycholeptics; oral
3.5
10.4
48
143
K08.1
ICD-10 Finland
Loss of teeth due to accident, extraction or local periodontal disease
2.3
10.4
96
437
R05
ICPC
Cough
1.7
10.4
228
1444
C07AB07
ATC
bisoprolol; oral
1.6
10.4
378
2749
N39.0
ICD-10 Finland
Urinary tract infection, site not specified
2.0
10.3
141
758
M02AA07
ATC
piroxicam; topical
1.6
10.3
341
2416
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
1.8
10.2
178
1048
A07EA06
ATC
budesonide; oral, local oral
3.3
10.2
49
151
Z87.1
ICD-10 Finland
Personal history of diseases of the digestive system
1.5
10.1
420
3142
M01AE02
ATC
naproxen; oral, rectal
1.5
10.1
595
4821
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
10.0
178
1053
N06AX16
ATC
venlafaxine; oral
1.9
10.0
154
869
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.6
10.0
330
2334
NA1BG
NOMESCO Finland
Cervical spine MRI examination with high intensity magnet
2.8
10.0
63
233
M51.3
ICD-10 Finland
Other specified intervertebral disc degeneration
2.3
10.0
91
412
SPAT1212
SPAT
Extensive examination of musculoskeletal system
2.4
9.9
86
380
L02
ICPC
Back symptom/complaint
2.2
9.9
105
509
J01DB01
ATC
cefalexin; oral
1.6
9.9
842
7392
E86
ICD-10 Finland
Volume depletion
16.9
9.9
15
9
A03FA01
ATC
metoclopramide; systemic, rectal
1.7
9.9
207
1293
H02AB07
ATC
prednisone; oral
1.9
9.8
141
775
D07AC13
ATC
mometasone; topical
1.6
9.8
277
1881
AN1
HP
Coronary angiography
2.5
9.7
78
329
N05CD07
ATC
temazepam; oral
2.1
9.7
114
578
R12
ICD-10 Finland
Heartburn
2.4
9.7
81
352
C01DA02
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
1.9
9.6
140
774
C07AA05
ATC
propranolol; systemic
1.7
9.6
206
1293
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
1.9
9.6
139
766
R52.9
ICD-10 Finland
Pain, unspecified
2.2
9.5
93
437
R11
ICD-10 Finland
Nausea and vomiting
2.3
9.4
85
383
K59.09
ICD-10 Finland
Constipation, unspecified
2.7
9.4
64
248
N05CF02
ATC
zolpidem; oral
1.8
9.4
174
1044
D06
ICPC
Abdominal pain localized other
2.2
9.3
94
448
SPAT1336
SPAT
Request for examination
3.1
9.2
48
158
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.1
9.1
49
164
R41.8
ICD-10 Finland
Other and unspecified symptoms and signs involving cognitive functions and awareness
2.4
9.1
77
334
208
Kela drug reimbursment
Ulcerative colitis and Crohn's disease
2.7
9.1
59
223
J01CR02
ATC
amoxicillin and beta-lactamase inhibitor; systemic
1.5
9.1
534
4283
K50.9
ICD-10 Finland
Crohn disease, unspecified
4.8
9.1
29
62
UJF45
NOMESCO Finland
Flexible sigmoidoscopy with biopsy
2.3
9.1
82
368
M01AC06
ATC
meloxicam; systemic, rectal
1.5
9.0
339
2463
C03CA01
ATC
furosemide; systemic
1.7
9.0
216
1397
WZB00
NOMESCO Finland
Telephone receipt or other advice
1.6
9.0
298
2101
M01AH02
ATC
rofecoxib; oral
2.0
9.0
120
641
Z71.2
ICD-10 Finland
Person consulting for explanation of investigation findings
1.6
9.0
236
1564
A02BA03
ATC
famotidine; systemic
3.4
9.0
42
127
M02AA10
ATC
ketoprofen; topical
1.8
9.0
156
916
D82
ICPC
Teeth/gum disease
1.5
9.0
369
2736
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.8
8.9
57
214
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.9
8.8
132
736
N06AB06
ATC
sertraline; oral
2.0
8.8
122
660
B01AC04
ATC
clopidogrel; oral
2.2
8.8
93
451
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
2.5
8.8
69
288
R02
ICPC
Shortness of breath/dyspnoea
2.0
8.8
114
602
M54.3
ICD-10 Finland
Sciatica
2.6
8.8
64
259
L13
ICPC
Hip symptom/complaint
1.8
8.8
145
835
SFC01
NOMESCO Finland
Adjuvant procedure of filling therapy
1.6
8.7
264
1817
X58
ICD-10 Finland
Exposure to other specified factors
1.9
8.7
138
785
R03AK07
ATC
formoterol and budesonide; inhalant
1.7
8.7
198
1265
R06AX27
ATC
desloratadine; oral
1.6
8.7
303
2162
F33.9
ICD-10 Finland
Recurrent depressive disorder, unspecified
2.8
8.7
55
205
M01AX01
ATC
nabumetone; oral
3.0
8.6
49
168
C10AA05
ATC
atorvastatin; oral
1.6
8.6
253
1730
K58
ICD-10 Finland
Irritable bowel syndrome
4.0
8.6
33
85
F41.9
ICD-10 Finland
Anxiety disorder, unspecified
2.0
8.6
110
577
R03AC03
ATC
terbutaline; inhalant
1.8
8.6
149
876
R03AK06
ATC
salmeterol and fluticasone; inhalant
1.9
8.5
138
788
SAA01
NOMESCO Finland
Simple examination of mouth
1.5
8.5
739
6376
Z03.89
ICD-10 Finland
Observation for other suspected diseases and conditions
1.9
8.5
135
769
A07AA02
ATC
nystatin; oral
2.4
8.5
68
289
I84.2
ICD-10 Finland
Internal hemorrhoids without complication
2.3
8.5
81
374
Z01.4
ICD-10 Finland
Gynaecological examination (general)(routine)
1.7
8.5
179
1113
J01EE02
ATC
sulfadiazine and trimethoprim; systemic
1.6
8.5
292
2073
R05FB02
ATC
cough suppressants and expectorants
1.5
8.5
344
2539
NA3BG
NOMESCO Finland
Lumbar spine MRI examination with high intensity magnet
2.1
8.5
95
473
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
2.6
8.4
58
227
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
2.2
8.4
88
427
7819X
ICD-9 Finland
Symptoms involving nervous and musculoskeletal systems, Other symptoms involving nervous and musculoskeletal systems[SYMPTOMATA ALIA SYSTEMATIS NERVORUM ET MUSCULOSCEL]
7.9
8.4
18
23
P06
ICPC
Sleep disturbance
2.0
8.3
109
580
K20
ICD-10 Finland
Oesophagitis
5.9
8.3
22
38
K51.9
ICD-10 Finland
Ulcerative colitis, unspecified
3.2
8.3
41
130
M01AH01
ATC
celecoxib; oral (coxibs)
1.7
8.3
169
1043
N05BE01
ATC
buspirone; oral
3.5
8.2
37
109
M54.6
ICD-10 Finland
Pain in thoracic spine
2.3
8.2
75
342
H03AA01
ATC
levothyroxine sodium; systemic
1.6
8.2
222
1486
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
2.8
8.1
51
187
M05BA07
ATC
risedronic acid; oral
3.4
8.1
38
116
EB1AA
NOMESCO Finland
Tooth X-ray examination
1.4
8.0
548
4483
E83.50
ICD-10 Finland
Hypercalcemia
22.2
8.0
11
5
R19.4
ICD-10 Finland
Change in bowel habit
3.8
8.0
32
86
A10AC01
ATC
insulin (human); parenteral (insulins and analog. for injection, intermediate-acting)
2.3
8.0
70
312
XQ800
NOMESCO Finland
Prick test
2.0
7.9
96
495
N06CA01
ATC
amitriptyline and psycholeptics; systemic
2.0
7.9
98
510
R07.3
ICD-10 Finland
Other chest pain
2.1
7.9
93
472
N83.2
ICD-10 Finland
Other and unspecified ovarian cysts
1.9
7.9
111
605
A02BX02
ATC
sucralfate; oral
2.8
7.9
48
176
K08.80
ICD-10 Finland
Toothache NOS
2.1
7.8
90
452
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
2.1
7.8
88
439
E0000UV
ATC
NA
1.5
7.8
389
2987
N05CF01
ATC
zopiclone; oral
1.5
7.8
288
2073
D07AC01
ATC
betamethasone; topical
1.5
7.8
302
2198
F32.10
ICD-10 Finland
Moderate depressive episode without somatic syndrome
2.0
7.8
96
497
Z01.2
ICD-10 Finland
Dental examination
1.5
7.7
430
3371
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
1.7
7.7
172
1087
JAH01
NOMESCO Finland
Laparoscopy
2.6
7.7
53
207
A09AA02
ATC
multienzymes (lipase, protease etc.)
5.3
7.7
22
42
N02AJ06
ATC
codeine and paracetamol; systemic
1.5
7.7
346
2601
K50.0
ICD-10 Finland
Crohn disease of small intestine
4.4
7.7
26
60
SFA10
NOMESCO Finland
Fillning on one surface of tooth
1.4
7.7
537
4404
R03DC03
ATC
montelukast; oral
1.7
7.7
170
1075
C10AA07
ATC
rosuvastatin; oral
1.7
7.6
165
1035
R13
ICD-10 Finland
Dysphagia
2.4
7.6
62
267
J31.0
ICD-10 Finland
Chronic rhinitis
2.1
7.6
84
415
1370
FHL
Colonoscopy, whole colon
11.9
7.6
13
11
206
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
1.9
7.6
107
585
5301A
ICD-9 Finland
Diseases of oesophagus, Oesophagitis[OESOPHAGITIS REFLUENS]
10.1
7.5
14
14
6451
FHL
Dilatation
10.1
7.5
14
14
F34.1
ICD-10 Finland
Dysthymia
2.8
7.5
45
163
M54.2
ICD-10 Finland
Cervicalgia
2.2
7.5
73
343
I25.9
ICD-10 Finland
Chronic ischaemic heart disease, unspecified
2.4
7.5
64
280
N06AB03
ATC
fluoxetine; oral
1.8
7.5
131
768
G04CA02
ATC
tamsulosin; oral
1.8
7.5
131
768
J45.0
ICD-10 Finland
Predominantly allergic asthma
1.9
7.5
102
551
G04BD12
ATC
mirabegron; oral
2.1
7.4
81
400
A01AB04
ATC
amphotericin B; local oral
2.6
7.4
51
200
K02.1
ICD-10 Finland
Caries of dentine
1.4
7.3
583
4878
J30.10
ICD-10 Finland
Allergic rhinitis due to pollen
2.2
7.3
71
333
M01AX17
ATC
nimesulide; oral
1.6
7.3
202
1352
N03AE01
ATC
clonazepam; systemic
2.4
7.3
61
267
SPAT1104
SPAT
Monitoring of emergency patient
2.4
7.3
60
260
5355X
ICD-9 Finland
Gastritis and duodenitis, Unspecified gastritis and gastroduodenitis
15.9
7.2
11
7
WX722
NOMESCO Finland
PEEP
2.8
7.2
44
162
X59
ICD-10 Finland
Exposure to unspecified factor
1.6
7.2
175
1134
TPH04
NOMESCO Finland
Cathetrisation of vein
1.6
7.2
182
1191
E03.80
ICD-10 Finland
Hypothyroidism caused by autoimmune thyroiditis
3.9
7.2
28
74
F33.2
ICD-10 Finland
Recurrent depressive disorder, current episode severe without psychotic symptoms
2.4
7.2
57
243
N06AB10
ATC
escitalopram; oral
1.6
7.2
209
1418
WX110
NOMESCO Finland
Local anesthesy
1.4
7.1
701
6081
S01GX01
ATC
cromoglicic acid; ophthalmic
1.6
7.1
214
1465
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
1.8
7.1
112
635
K50.8
ICD-10 Finland
Other Crohn disease
3.9
7.1
27
70
R52.2
ICD-10 Finland
Other chronic pain
3.0
7.1
38
129
M53.1
ICD-10 Finland
Cervicobrachial syndrome
1.9
7.0
110
623
N03AG01
ATC
valproic acid; systemic, rectal
2.3
7.0
64
293
A11
ICPC
Chest pain NOS
2.3
6.9
63
285
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
2.1
6.9
71
343
D50.9
ICD-10 Finland
Iron deficiency anaemia, unspecified
2.3
6.9
63
287
A10AB05
ATC
insulin aspart; parenteral (insulins and analog. for injection, fast-acting)
2.3
6.9
63
288
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
1.5
6.9
257
1848
SXB00
NOMESCO Finland
Removeal of sutres from oral mucosa
2.2
6.8
65
302
N39.3
ICD-10 Finland
Stress incontinence
2.1
6.8
72
350
R03BA02
ATC
budesonide; inhalant
1.6
6.8
177
1168
A41.5
ICD-10 Finland
Sepsis due to other Gram-negative organisms
3.7
6.8
28
78
J01MA01
ATC
ofloxacin; systemic
2.1
6.8
75
374
I20.09
ICD-10 Finland
Unstable angina
2.9
6.8
39
137
A10AE04
ATC
insulin glargine; parenteral
2.1
6.8
70
339
SHB00
NOMESCO Finland
Prepation and fitting of bite rail to mouth
1.8
6.8
111
638
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
1.9
6.8
93
505
Z71.8
ICD-10 Finland
Other specified counselling
1.5
6.8
240
1705
D11
ICPC
Diarrhoea
1.8
6.8
123
731
SFA20
NOMESCO Finland
Filling on two surfaces of tooth
1.4
6.8
567
4760
5645A
ICD-9 Finland
Functional digestive disorders, not elsewhere classified, Functional diarrhoea
16.8
6.7
10
6
L15
ICPC
Knee symptom/complaint
1.6
6.7
189
1268
G03CA04
ATC
estriol; systemic, vaginal
2.2
6.7
69
330
SHA02
NOMESCO Finland
Correction of physiology of bite - basic therapy visit
2.1
6.7
78
394
R00.2
ICD-10 Finland
Palpitations
2.1
6.7
76
381
J01CA08
ATC
pivmecillinam; oral
1.4
6.7
408
3230
C10AX09
ATC
ezetimibe; oral
2.1
6.7
69
332
A03DA02
ATC
pitofenone and analgesics; systemic
4.0
6.7
25
64
C07AB02
ATC
metoprolol; systemic
1.6
6.7
158
1017
G04BD08
ATC
solifenacin; oral
2.3
6.7
59
265
R05
ICD-10 Finland
Cough
1.6
6.7
181
1204
XF402
NOMESCO Finland
ECG with work load test
2.0
6.6
82
428
B03BA03
ATC
hydroxocobalamin; parenteral
2.4
6.6
53
227
F33.11
ICD-10 Finland
Recurrent depression, moderate episode of somatic syndrome
3.3
6.6
31
96
S01CA01
ATC
dexamethasone and antiinfectives; ophthalmic (ophth., corticosteroids and antiinfectives in comb.)
1.5
6.6
292
2173
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
1.7
6.6
149
948
M48.0
ICD-10 Finland
Spinal stenosis
1.9
6.6
91
493
XG412
NOMESCO Finland
Flow-volume spirometry with bronchospasmolysis
2.3
6.6
58
260
E89.01
ICD-10 Finland
Postsurgical hypothyroidism
8.8
6.6
13
15
F60.31
ICD-10 Finland
Emotionally unstable personality disorder, borderline condition
4.4
6.6
22
51
I25.2
ICD-10 Finland
Old myocardial infarction
2.6
6.5
44
173
N03AF01
ATC
carbamazepine; oral, rectal
2.5
6.5
49
202
FN1BC
NOMESCO Finland
Extensive angiography of hear and/or coronary arteries
2.7
6.5
40
149
L48
ICPC
Musculoskeletal, Clarification/discussion RFE/demand
5.1
6.5
19
38
F60.3
ICD-10 Finland
Emotionally unstable personality disorder
5.4
6.5
18
34
D64.9
ICD-10 Finland
Anaemia, unspecified
2.0
6.5
76
386
N05AF03
ATC
chlorprothixene; systemic
3.1
6.5
33
109
R01AD58
ATC
fluticasone, combinations; inhalant, nasal
1.5
6.4
222
1567
Z76.9
ICD-10 Finland
Person encountering health services in unspecified circumstances
2.0
6.4
76
388
SPAT1223
SPAT
Implementation of physical therapy rehabilitation plan
1.5
6.4
252
1828
K90.4
ICD-10 Finland
Malabsorption due to intolerance, not elsewhere classified
70.2
6.4
7
*
M70.6
ICD-10 Finland
Trochanteric bursitis
1.8
6.4
105
605
T78.4
ICD-10 Finland
Allergy, unspecified
2.3
6.4
58
265
R5140
NOMESCO Finland
Monitoring the use of the aid
1.9
6.4
86
464
J01CA04
ATC
amoxicillin; systemic
1.4
6.3
854
7752
J02AC02
ATC
itraconazole; systemic
1.6
6.3
154
995
F33.00
ICD-10 Finland
Recurrent depression, mild episode without somatic syndrome
3.5
6.3
27
78
Z03.3
ICD-10 Finland
Observation for suspected nervous system disorder
2.2
6.3
60
281
SXC05
NOMESCO Finland
Other oral or dental procedure
2.1
6.3
71
357
00919
ICD-8 Finland
Diarrhoeal disease, Diarrhoea
11.1
6.3
11
10
M54.9
ICD-10 Finland
Dorsalgia, unspecified
1.8
6.3
107
622
M19.0
ICD-10 Finland
Primary arthrosis of other joints
2.0
6.3
77
399
J18.9
ICD-10 Finland
Pneumonia, unspecified
1.6
6.3
184
1250
D12.6
ICD-10 Finland
Benign neoplasm: Colon, unspecified
2.6
6.3
44
175
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
1.8
6.2
103
593
U02
ICPC
Urinary frequency/urgency
1.7
6.2
125
766
R21
ICPC
Throat symptom/complaint
1.5
6.2
222
1578
D01AC20
ATC
imidazoles/triazoles in combination with corticosteroids; topical
1.5
6.2
203
1413
SPAT1216
SPAT
Assessment of functional ability
1.7
6.2
125
768
G04CA01
ATC
alfuzosin; oral
2.0
6.2
72
364
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.0
6.2
75
389
M51.9
ICD-10 Finland
Intervertebral disc disorder, unspecified
4.0
6.2
23
59
G04BD07
ATC
tolterodine; oral
2.5
6.2
47
196
M01AG02
ATC
tolfenamic acid; oral, rectal
1.6
6.2
151
978
M05BA04
ATC
alendronic acid; oral
2.0
6.2
76
394
J01DA09
ATC
[U] cefadroxil; inhalant, oral
1.5
6.2
263
1939
K52.2
ICD-10 Finland
Allergic and dietetic gastroenteritis and colitis
5.4
6.2
17
32
Z03
ICD-10 Finland
Medical observation and evaluation for suspected diseases and conditions, ruled out
1.9
6.2
82
439
K02.2
ICD-10 Finland
Caries of cementum
2.7
6.1
40
153
Z09.0
ICD-10 Finland
Follow-up examination after surgery for other conditions
2.0
6.1
76
396
FN1AT
NOMESCO Finland
Endovascular dilatation of coronary arteries (PTCA)
3.1
6.1
31
102
F43.22
ICD-10 Finland
Adaptation disorder with mixed anxiety and depression
2.4
6.1
48
205
I63.9
ICD-10 Finland
Cerebral infarction, unspecified
2.1
6.1
65
318
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
2.1
6.1
68
341
R4110
NOMESCO Finland
Physiotherapy
1.5
6.1
229
1645
R19.8
ICD-10 Finland
Other specified symptoms and signs involving the digestive system and abdomen
4.7
6.1
19
41
E10
ICD-10 Finland
Type 1 diabetes mellitus
3.8
6.1
24
65
215
Kela drug reimbursment
Diabetes, non-insulin-treated
1.6
6.1
165
1099
M75.1
ICD-10 Finland
Rotator cuff syndrome
1.5
6.1
189
1303
I20.99
ICD-10 Finland
Angina pectoris, unspecified
2.5
6.0
44
181
J32.0
ICD-10 Finland
Chronic maxillary sinusitis
2.0
6.0
73
378
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
1.7
6.0
110
658
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: E4_LACTOSEINT – Lactose intolerance
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).