Polycystic ovarian syndrome, concortium definition

E4_PCOS_CONCORTIUM

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule

Sex only females

180574

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Check conditions None

180574

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Filter registries

Hospital Discharge: ICD-10 L68.0#, N92.5, N92.6
Hospital discharge: ICD-9 626|7041
Hospital discharge: ICD-8 626|70405
Hospital discharge: excluded ICD-10 E2839|E24|E23[0-4]|E25|F50|F11|D25|D352|E22|E221|C56|D27|Q96|N643|C74
Hospital discharge: excluded ICD-9 2563|25631|2568|2550|2580|2434A|2532[AB]2552|3071A|3072A|3075[AB]|304|2180|253X|2531X|2531A|2395|220|7586|2531A|2270|1940
Hospital discharge: excluded ICD-8 2561|255|258|2561|255|3065|304|21899|2262|253|253|183|22099|7595|253|2260
Cause of death: ICD-10 L68.0#, N92.5, N92.6
Cause of death: ICD-9 626|7041
Cause of death: ICD-8 626|70405
Cause of death: excluded ICD-10 E2839|E24|E23[0-4]|E25|F50|F11|D25|D352|E22|E221|C56|D27|Q96|N643|C74
Cause of death: excluded ICD-9 2563|25631|2568|2550|2580|2434A|2532[AB]2552|3071A|3072A|3075[AB]|304|2180|253X|2531X|2531A|2395|220|7586|2531A|2270|1940
Cause of death: excluded ICD-8 2561|255|258|2561|255|3065|304|21899|2262|253|253|183|22099|7595|253|2260

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Check minimum number of events None

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Include endpoints

26010

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E4_PCOS_CONCORTIUM

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF6v3

Summary Statistics

Key figures

All Female Male
Number of individuals 25117 25117 -
Unadjusted prevalence (%) 8.14 14.47 -
Mean age at first event (years) 38.55 38.55 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 0.55 [0.47, 0.63] 5.1e-16 1359
15 years 0.00 0.42 [0.36, 0.48] 9.6e-32 574
5 years 0.00 0.31 [0.25, 0.40] 3.7e-21 85
1 year 0.00 0.34 [0.21, 0.57] 3.6e-5 16

Cumulative Incidence

Correlations

Index endpoint: E4_PCOS_CONCORTIUM – Polycystic ovarian syndrome, concortium definition
GWS hits:

Survival analyses between endpoints

Plot

before Polycystic ovarian syndrome, concortium definition
after Polycystic ovarian syndrome, concortium definition

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Drugs most likely to be purchased after Polycystic ovarian syndrome, concortium definition