erythema infectiosum: usually a benign childhood condition characterized by a classic slapped-cheek appearance (see the image below) and lacy exanthem.It results from infection with human parvovirus (PV) B19, an erythrovirus.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
61 |
4. Check minimum number of eventsNone |
61 |
5. Include endpointsNone |
61 |
6. Filter based on genotype QC (FinnGen only) |
61 |
Control definitions (FinnGen only)
- Control exclude
- L12_URTICARIAERYTHEMA
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- L53
- Name in latin
- Erythema anulare centrifugum
Similar endpoints
↥List of similar endpoints to
Erythema annulare centrifugum
based on the number of shared cases.
Similar with more cases:
- Other erythematous conditions
- Urticaria and erythema
- Diseases of the skin and subcutaneous tissue
- Any event in hilmo or specialist outpatient
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 491 | 327 | 161 |
| Only index persons | 439 | 297 | 142 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.00 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 55.65 | 56.35 | 53.95 |
| Only index persons | 54.82 | 55.33 | 53.75 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 61 | 44 | 17 |
| Unadjusted period prevalence (%) | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | 56.92 | 55.06 | 61.74 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 54
- Matched controls
- 539
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L53.1
ICD-10 Finland
Erythema annulare centrifugum
+∞
72.2
52
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
10.0
10.0
21
32
D07AC13
ATC
mometasone; topical
5.8
8.1
28
84
L30.9
ICD-10 Finland
Dermatitis, unspecified
6.9
8.0
22
49
D07AC01
ATC
betamethasone; topical
4.4
6.3
32
133
Mortality – FinRegistry
↥Association
Association between endpoint L12_ERYTH_ANNULCENTRIFUG and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have L12_ERYTH_ANNULCENTRIFUG.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: L12_ERYTH_ANNULCENTRIFUG – Erythema annulare centrifugum
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
Extremity
rg [CI]
Extremity
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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