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This is a non-core endpoint: only basic statistics are computed.

Dietary selenium deficiency

E4_SELE_DEF

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E59
  • Cause of death: ICD-10 E59

2 out of 7 registries used, show all original rules.

5

4. Check minimum number of events

None

5

5. Include endpoints

None

5

6. Filter based on genotype QC (FinnGen only)

5

Control definitions (FinnGen only)

Control exclude
E4_NUTRIDEF

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
E50-E64
Name in latin
Deficientia selenii diaetaria

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Not enough data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 44 24 19
Only index persons 31 18 13
Unadjusted period prevalence (%)
Whole population 0.00 0.00 0.00
Only index persons 0.00 0.00 0.00
Median age at first event (years)
Whole population 62.68 68.80 53.80
Only index persons 61.36 66.81 53.80

-FinnGen-

Key figures

All Female Male
Number of individuals 5 - -
Unadjusted period prevalence (%) 0.00 - -
Median age at first event (years) 56.53 - -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3013707) Erythrocyte sedimentation rate by Westergren method
5
29
+∞
0.84
6.2
3.0
mm/h
6.8
12.0
—
5
24
(3037467) Urinalysis macro (dipstick) panel - Urine
5
32
+∞
0.80
2.8
3.8
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
0
11
0.00
0.24
0.0
3.6
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
0
11
0.00
0.24
0.0
3.1
—
0.8
—
0
6
(3003338) MCHC [Mass/volume]
5
39
+∞
0.24
26.8
26.1
g/l
335.6
331.3
—
5
39
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
5
40
+∞
0.24
5.6
4.7
mmol/l
1.6
1.6
—
5
35
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
5
38
+∞
0.24
9.4
10.9
u/l
67.4
88.3
—
5
33
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
5
43
+∞
0.00
13.8
17.5
ml/min/173m2
76.8
85.4
—
5
34
(3016502) Oxygen saturation in Arterial blood
0
8
0.00
0.00
0.0
11.4
—
96.7
—
0
8
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
5
42
+∞
0.00
7.6
5.3
mmol/l
2.1
2.7
—
5
37
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3002173) Hemoglobin [Mass/volume] in Arterial blood
0
6
0.00
0.00
0.0
14.7
—
117.5
—
0
6
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
0
5
0.00
0.00
0.0
15.8
—
0.6
—
0
5
(3000494) Fungus identified in Specimen by Culture
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(3003458) Phosphate [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
6.6
—
1.0
—
0
7
(40761511) CBC panel - Blood by Automated count
5
44
+∞
0.00
15.6
19.0
—
—
—
0
0
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
0
5
0.00
0.00
0.0
15.8
—
1.0
—
0
5
(3025941) Bacteria identified in Stool by Culture
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
0
5
0.00
0.00
0.0
2.0
—
—
—
0
0
(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.8
—
266.8
—
0
5
(40768797) Stomach Pathology biopsy report
0
7
0.00
0.00
0.0
1.4
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint E4_SELE_DEF and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have E4_SELE_DEF.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: E4_SELE_DEF – Dietary selenium deficiency

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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