This is a non-core endpoint: only basic statistics are computed.
See these related core endpoints for full statistics:
Amyloidosis
E4_AMYLOIDOSIS
amyloidosis: A disorder characterized by the localized or diffuse accumulation of amyloid protein in various anatomic sites. It may be primary, due to clonal plasma cell proliferations; secondary, due to long standing infections, chronic inflammatory disorders, or malignancies; or familial. It may affect the nerves, skin, tongue, joints, heart, liver, spleen, kidneys and adrenal glands.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
715 |
4. Check minimum number of eventsNone |
715 |
5. Include endpoints |
727 |
6. Filter based on genotype QC (FinnGen only) |
727 |
Control definitions (FinnGen only)
- Control exclude
- E4_METABOLIA
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
- Parent code in ICD-10
- E70-E90
- Name in latin
- Amyloidosis
Similar endpoints
↥List of similar endpoints to
Amyloidosis
based on the number of shared cases.
Similar with more cases:
- Metabolic disorders
- Endocrine, nutritional and metabolic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded from FinRegistry analyses (omitted endpoint).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 727 | 347 | 380 |
| Unadjusted period prevalence (%) | 0.14 | 0.12 | 0.17 |
| Median age at first event (years) | 67.78 | 63.02 | 72.13 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
Not a core endpoint, no data to show.
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 622
- Matched controls
- 6221
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E85.9
ICD-10 Finland
Amyloidosis, unspecified
+∞
234.7
210
*
E85.4
ICD-10 Finland
Organ-limited amyloidosis
+∞
115.3
107
*
E85.3
ICD-10 Finland
Secondary systemic amyloidosis
+∞
101.9
95
*
E85.80
ICD-10 Finland
Meretoja sick
+∞
101.9
95
*
N08.4*E85.9
ICD-10 Finland
Glomerular disorders in amyloidosis
+∞
99.7
93
*
E85.89
ICD-10 Finland
Other amyloidosis
+∞
92.0
86
*
I68.0*E85.9
ICD-10 Finland
Cerebral amyloid angiopathy
+∞
77.8
73
*
I43.1*E85.9
ICD-10 Finland
Cardiac amyloidosis
+∞
77.8
73
*
H19.8*E85.80
ICD-10 Finland
Reticular keratitis in Meretoja's patients
+∞
70.1
66
*
C03CA01
ATC
furosemide; systemic
4.2
59.5
335
1362
138
Kela drug reimbursment
Severe anaemia associated with chronic renal failure
25.7
56.1
79
35
123
Kela drug reimbursment
Chronic disorders of vitamin D metabolism
23.1
55.7
81
40
7140A
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SEROPOSITIVA]
33.6
52.8
69
23
A11CC03
ATC
alfacalcidol; systemic
23.4
49.2
71
34
XW000
NOMESCO Finland
Bone marrow biopsy
10.7
48.3
97
105
C90.0
ICD-10 Finland
Multiple myeloma
30.3
47.1
63
23
N08.4
ICD-10 Finland
Glomerular disorders in other endocrine, nutritional and metabolic diseases
+∞
45.4
43
*
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
9.1
45.3
100
128
GD1AA
NOMESCO Finland
Thorax X-ray examination
3.4
44.7
370
1894
M05.8
ICD-10 Finland
Other seropositive rheumatoid arthritis
7.2
41.7
108
177
E85.0
ICD-10 Finland
Non-neuropathic heredofamilial amyloidosis
+∞
41.1
39
*
N18.9
ICD-10 Finland
Chronic kidney disease, unspecified
7.3
40.3
103
165
71238
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides alia definita
29.4
40.1
54
20
202
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
4.8
40.0
152
396
A12AA04
ATC
calcium carbonate; oral
26.2
38.2
53
22
Z49.1
ICD-10 Finland
Extracorporeal dialysis
31.1
37.0
49
17
TK800
NOMESCO Finland
Hemodialysis
20.6
35.5
53
28
9732/3-C42.1
ICD-O-3
Plasma cell myeloma of bone marrow
39.3
35.1
44
12
L01BA01
ATC
methotrexate; systemic (folic acid analog.)
8.1
35.1
82
114
PBL10
NOMESCO Finland
Construction of arteriovenous fistula from radial artery
39.8
32.9
41
11
N18.0
ICD-10 Finland
End-stage renal disease
42.6
32.5
40
10
H18.5
ICD-10 Finland
Hereditary corneal dystrophies
28.7
31.9
43
16
2773B
ICD-9 Finland
Other and unspecified disorders of metabolism, Amyloidosis[AMYLOIDOSIS SECUNDARIA]
+∞
31.5
30
*
L04AA01
ATC
[U] ciclosporin; systemic
20.2
31.4
47
25
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
4.0
30.3
137
412
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.5
29.8
163
572
I50.9
ICD-10 Finland
Heart failure, unspecified
3.5
28.6
158
558
A12AX
ATC
Calcium, combinations with vitamin D and/or other drugs
2.7
28.6
276
1416
153
Kela drug reimbursment
Lenalidomid
41.1
28.3
35
9
D47.2
ICD-10 Finland
Monoclonal gammopathy of undetermined significance (MGUS)
16.1
27.7
45
30
NJ3DA
NOMESCO Finland
Long bones of extremities X-ray examination
49.6
27.7
33
7
FM1AE
NOMESCO Finland
Standard cardiac ultrasound examination
3.2
27.0
167
638
GD1UA
NOMESCO Finland
Thorax X-ray examination outside radiological department
3.5
26.1
141
486
FM1DG
NOMESCO Finland
Very extensive MRI examination of heart with high intesity magnet
26.4
25.5
35
14
FJA10
NOMESCO Finland
Transvenous biopsy of right ventricle
52.4
25.5
30
6
NA1AA
NOMESCO Finland
Cervical spine X-ray examination without contrast
7.9
25.3
59
81
I68.0
ICD-10 Finland
Cerebral amyloid angiopathy
+∞
25.2
24
*
I43.1
ICD-10 Finland
Cardiomyopathy in metabolic diseases
+∞
25.2
24
*
71239
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Arthritis rheumatoides NUD
18.3
24.7
38
22
FM1EE
NOMESCO Finland
Extensive structural and functional ultrasound examination of heart
2.9
24.6
187
812
L04AX04
ATC
lenalidomide; oral
50.5
24.5
29
6
N18.8
ICD-10 Finland
Other chronic renal failure
9.1
24.3
52
62
B03XA01
ATC
erythropoietin; parenteral
20.0
24.2
36
19
E87.1
ICD-10 Finland
Hypo-osmolality and hyponatraemia
39.3
24.1
30
8
M05.9
ICD-10 Finland
Seropositive rheumatoid arthritis, unspecified
9.0
23.8
51
61
J01EE01
ATC
sulfamethoxazole and trimethoprim; systemic
5.0
23.8
80
178
M06.9
ICD-10 Finland
Rheumatoid arthritis, unspecified
7.5
23.6
57
83
KA3AT
NOMESCO Finland
Biopsy of kidney with ultrasound guidance
17.0
23.5
37
23
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
8.2
22.5
51
67
V03AE01
ATC
polystyrene sulfonate; oral
20.4
22.4
33
17
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
3.6
22.2
109
346
L01AA03
ATC
melphalan; systemic
64.9
22.0
25
*
H19.8
ICD-10 Finland
Other disorders of sclera and cornea in diseases classified elsewhere
+∞
22.0
21
*
M04AA01
ATC
allopurinol; systemic
3.1
22.0
137
516
NA2AA
NOMESCO Finland
Thoracal spine X-ray examination without contrast
10.9
21.9
42
41
B03XA02
ATC
darbepoetin alfa; parenteral
12.2
21.5
39
34
A49.9
ICD-10 Finland
Bacterial infection, unspecified
3.5
21.5
109
354
L04AX01
ATC
azathioprine; systemic
5.7
21.0
62
118
N04.9
ICD-10 Finland
Nephrotic syndrome, unspecified
79.6
20.8
23
*
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
2.4
20.7
225
1179
H16.0
ICD-10 Finland
Corneal ulcer
5.7
20.7
61
116
N19
ICD-10 Finland
Unspecified kidney failure
6.5
20.6
55
92
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
19.1
20.6
31
17
137
Kela drug reimbursment
Uraemia requiring dialysis
19.1
20.6
31
17
190
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
33.8
20.3
26
8
AA1AD
NOMESCO Finland
CT of head and brain
2.5
20.1
190
919
GD1PA
NOMESCO Finland
X-ray examination of the lungs in one projection
3.8
19.9
90
265
NK6QA
NOMESCO Finland
Measurement of bone density from tow or more locations with X-ray
4.7
19.6
69
161
H02AB02
ATC
dexamethasone; systemic
3.5
19.3
99
323
J01MA12
ATC
levofloxacin; systemic
2.7
19.2
158
706
M08.0
ICD-10 Finland
Juvenile rheumatoid arthritis
56.9
19.0
22
*
WW300
NOMESCO Finland
Transfer of autologic stem cells
35.6
19.0
24
7
ZX120
NOMESCO Finland
Intravenous
3.6
19.0
90
276
E78.01
ICD-10 Finland
Pure hypercholesterolaemia
3.5
18.9
94
299
L99.0*E85.9
ICD-10 Finland
Amyloidosis of skin
+∞
18.8
18
*
127
Kela drug reimbursment
Transplant complication
15.7
18.6
30
20
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.5
18.4
67
161
C03DA01
ATC
spironolactone; oral
3.1
18.4
109
395
Z94.0
ICD-10 Finland
Kidney transplant status
20.1
18.3
27
14
L04AA06
ATC
mycophenolic acid; systemic
12.9
18.3
32
26
I50.0
ICD-10 Finland
Congestive heart failure
3.5
18.2
90
285
313
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab, tocilizumab and ustekinumab (rheumatoid diseases)
8.8
18.2
39
47
329
Kela drug reimbursment
Lenalidomide
54.2
18.1
21
*
NK4XE
NOMESCO Finland
Joint ultrasound examination not elsewhere classified
4.4
18.0
68
170
E85.8
ICD-10 Finland
Other amyloidosis
+∞
17.8
17
*
NA3AA
NOMESCO Finland
Lumbar spine X-ray examination without contrast
3.4
17.5
89
288
Z03.5
ICD-10 Finland
Observation for other suspected cardiovascular diseases
4.1
17.0
68
179
TNX10
NOMESCO Finland
Arthrocentesis, unspecified region, unspecified region
3.8
16.7
74
214
9283
FHL
Subtalar joint ossification surgery (or triple)
174.4
16.6
17
*
Z49.0
ICD-10 Finland
Preparatory care for dialysis
15.9
16.3
26
17
S01XA20
ATC
artificial tears and other indifferent preparations; ophthalmic
2.1
16.3
285
1807
E78.5
ICD-10 Finland
Hyperlipidaemia, unspecified
6.0
16.2
45
80
71200
ICD-8 Finland
Rheumatoid arthritis and allied conditions, Juvenile rheumatoid arthritis
48.8
16.1
19
*
L04AA13
ATC
leflunomide; oral
7.1
16.0
39
58
KA1AE
NOMESCO Finland
Kidney ultrasound examination
7.5
15.8
37
52
ZXA05
NOMESCO Finland
Left side
2.2
15.7
203
1126
KAS10
NOMESCO Finland
Allogenic transplantation of kidney from cadaver donor
27.1
15.7
21
8
WX002
NOMESCO Finland
Sedation and analgesia
2.4
15.6
153
743
AA1AA
NOMESCO Finland
Head X-ray examination
13.5
15.3
26
20
CBJ50
NOMESCO Finland
Operation for ptosis of eyebrow
20.7
15.2
22
11
281
Kela drug reimbursment
Abatacept, adalimumab, anakinra, certolizumab pegol, etanercept, golimumab, infliximab, ixekizumab, sarilumab, secukinumab and tocilizumab
7.9
15.1
34
45
R06.0
ICD-10 Finland
Dyspnoea
2.2
15.0
177
935
L04AX03
ATC
methotrexate; systemic (immunosuppressants)
3.2
15.0
84
291
KH1AE
NOMESCO Finland
Urinary tract ultrasound examination
3.9
15.0
63
174
PG1DE
NOMESCO Finland
Other extensive ultrasound examination of artery
4.8
14.9
50
111
I15.1
ICD-10 Finland
Hypertension secondary to other renal disorders
21.7
14.7
21
10
H02AB06
ATC
prednisolone; systemic
2.0
14.6
319
2170
PBM10
NOMESCO Finland
Closure of arteriovenous fistula of radial artery
+∞
14.6
14
*
XF404
NOMESCO Finland
Ambulatory ECG
3.1
14.6
84
297
H02.2
ICD-10 Finland
Lagophthalmos
37.0
14.5
18
5
TPH04
NOMESCO Finland
Cathetrisation of vein
2.3
14.5
151
754
R80
ICD-10 Finland
Isolated proteinuria
17.5
14.4
22
13
9272
FHL
Metatarsophalangeal joint resection
27.9
14.3
19
7
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
4.5
14.3
51
121
B03XA03
ATC
methoxy polyethylene glycol-epoetin beta; parenteral
43.5
14.2
17
*
N17.9
ICD-10 Finland
Acute renal failure, unspecified
4.8
14.1
47
104
WX892
NOMESCO Finland
Monitored bed care
3.5
14.0
67
207
A07EC01
ATC
sulfasalazine; oral, rectal
3.2
13.9
78
270
9314
FHL
Total knee endoprosthesis (also includes patellar part)
20.6
13.8
20
10
M01CB01
ATC
sodium aurothiomalate; parenteral
10.0
13.8
27
28
J05AB01
ATC
aciclovir; systemic
2.3
13.8
151
769
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
5.9
13.7
38
68
CG2T4
NOMESCO Finland
Topography assessment of cornea
15.1
13.7
22
15
R50.9
ICD-10 Finland
Fever, unspecified
2.6
13.7
108
463
L04AD01
ATC
ciclosporin; systemic
9.7
13.6
27
29
I42.2
ICD-10 Finland
Other hypertrophic cardiomyopathy
13.2
13.5
23
18
CJE20
NOMESCO Finland
Phakoemulsification with implantation of artificial lens in posterior chamber
2.0
13.4
249
1581
KA2AE
NOMESCO Finland
Ultrasound examination transplanted kidney
21.7
13.4
19
9
PH2AE
NOMESCO Finland
Ultrasound examination of lower leg veins
2.8
13.4
91
356
J18.9
ICD-10 Finland
Pneumonia, unspecified
2.1
13.1
179
1005
CG2X4
NOMESCO Finland
Optical coherence tomography (OCT) of cornea
17.2
13.0
20
12
L88
ICPC
Rheumatoid/seropositive arthritis
4.8
13.0
43
94
TPX10
NOMESCO Finland
Implantation of vascular injection port
5.9
13.0
36
64
E87.5
ICD-10 Finland
Hyperkalaemia
29.0
13.0
17
6
E86
ICD-10 Finland
Volume depletion
51.1
12.9
15
*
NA1EA
NOMESCO Finland
Cervical spine X-ray examination with flexion
10.0
12.8
25
26
C07AB07
ATC
bisoprolol; oral
1.9
12.7
324
2286
DM1QA
NOMESCO Finland
Paranasal sinuses X-ray examination in one projection
4.7
12.7
43
97
9256
FHL
Synovectomy (knee 9311)
71.3
12.6
14
*
320
Kela drug reimbursment
Lanthanum carbonate, sevelamer and sucroferric oxyhydroxide
32.8
12.6
16
5
E83.50
ICD-10 Finland
Hypercalcemia
32.8
12.6
16
5
V03AE02
ATC
sevelamer; oral
32.8
12.6
16
5
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
2.0
12.6
204
1219
A04AA01
ATC
ondansetron; systemic, rectal
3.5
12.5
60
185
9284
FHL
Wrist ossification surgery
+∞
12.5
12
*
E85
ICD-10 Finland
Amyloidosis
+∞
12.5
12
*
E85.2
ICD-10 Finland
Heredofamilial amyloidosis, unspecified
+∞
12.5
12
*
B05DA
ATC
Isotonic solutions
13.5
12.5
21
16
ZXA00
NOMESCO Finland
Right side
2.0
12.5
200
1189
WX2DD
NOMESCO Finland
Low-dose CT of skeleton in whole body
132.5
12.5
13
*
TFJ02
NOMESCO Finland
Muscle biopsy of heart
132.5
12.5
13
*
FN1AC
NOMESCO Finland
Angiography of heart and/or coronary arteries
2.2
12.4
149
787
NE1AA
NOMESCO Finland
Pelvis X-ray examination
3.2
12.4
66
221
A46
ICD-10 Finland
Erysipelas
2.4
12.4
111
510
NCB20
NOMESCO Finland
Primary total prosthetic replacement of elbow joint
38.3
12.2
15
*
CG2S4
NOMESCO Finland
Photography of cornea
38.3
12.2
15
*
N39.1
ICD-10 Finland
Persistent proteinuria, unspecified
18.5
12.1
18
10
I61.1
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, cortical
18.5
12.1
18
10
C10AA05
ATC
atorvastatin; oral
1.9
12.0
237
1520
L28
ICPC
Limited function/disability (L)
2.3
11.9
122
598
ZXA10
NOMESCO Finland
Bilateral
2.2
11.8
138
719
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
2.8
11.8
77
295
B01AB05
ATC
enoxaparin; parenteral
1.9
11.8
210
1298
E78.00
ICD-10 Finland
Familial hypercholesterolaemia
16.8
11.7
18
11
R4120
NOMESCO Finland
Occupational therapy
3.5
11.7
56
173
QAJ10
NOMESCO Finland
Browlift
30.7
11.7
15
5
H04.10
ICD-10 Finland
Dry eye syndrome
2.7
11.6
80
317
1XX32
NOMESCO Finland
NA
66.2
11.6
13
*
N02AX02
ATC
tramadol; systemic, rectal
1.8
11.6
276
1882
PH1AE
NOMESCO Finland
Ultrasound examination of upper extremity veins
9.5
11.6
23
25
H02.4
ICD-10 Finland
Ptosis of eyelid
5.2
11.6
35
70
N08.4*E85.80
ICD-10 Finland
Glomerular disease in Meretoja's patients
+∞
11.5
11
*
QAJ20
NOMESCO Finland
Subperiosteal facelift
+∞
11.5
11
*
2773A
ICD-9 Finland
Other and unspecified disorders of metabolism, Amyloidosis[AMYLOIDOSIS PRIMARIA]
+∞
11.5
11
*
NB1AA
NOMESCO Finland
Shoulder X-ray examination without contrast
3.3
11.4
57
182
G56.0
ICD-10 Finland
Carpal tunnel syndrome
2.5
11.3
95
420
A07AA09
ATC
vancomycin; oral
9.1
11.3
23
26
WW200
NOMESCO Finland
Immunization
6.4
11.3
29
47
H02.3
ICD-10 Finland
Blepharochalasis
3.2
11.0
58
193
H02AB04
ATC
methylprednisolone; systemic
2.3
11.0
109
524
EP1AE
NOMESCO Finland
Neck ultrasound examination
4.1
10.9
42
108
ZX108
NOMESCO Finland
Inhalation
12.2
10.9
19
16
M05BA04
ATC
alendronic acid; oral
2.7
10.9
77
308
WX100
NOMESCO Finland
Conjunctival surface anesthesia
2.4
10.6
100
467
NC1AA
NOMESCO Finland
Elbow X-ray examination without contrast
5.2
10.6
32
64
Z31.5
ICD-10 Finland
Genetic counselling
4.6
10.6
36
82
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
6.4
10.6
27
44
YNB10
NOMESCO Finland
Collection of stem cells for transplant
111.8
10.4
11
*
7143C
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Juvenile chronic polyarthritis[POLYARTHRITIS JUVENILIS SERONEGATIVA]
+∞
10.4
10
*
E85.1
ICD-10 Finland
Neuropathic heredofamilial amyloidosis
+∞
10.4
10
*
QA4S1
NOMESCO Finland
Photography of skin or subcutaneous tissue in face
33.1
10.4
13
*
TPH90
NOMESCO Finland
Removal of fixed intravenous catheter
9.0
10.3
21
24
QX2XE
NOMESCO Finland
Ultrsound examination of soft tissue not elsewhere classified
6.1
10.2
27
46
XFP20
NOMESCO Finland
Check up of cardiac pacemaker
2.9
10.2
63
233
A02BC02
ATC
pantoprazole; systemic
1.7
10.1
389
3037
R4110
NOMESCO Finland
Physiotherapy
1.9
10.0
168
1003
M08.3
ICD-10 Finland
Juvenile polyarthritis (seronegative)
40.7
10.0
12
*
JN3AA
NOMESCO Finland
Abdominal X-ray examination without contrast
3.6
10.0
44
128
J01FF01
ATC
clindamycin; systemic
1.9
9.9
172
1042
7140B
ICD-9 Finland
Rheumatoid arthritis and other inflammatory polyarthropathies, Rheumatoid arthritis[ARTHRITIS RHEUMATOIDES SERONEGATIVA]
12.4
9.9
17
14
L01AA01
ATC
cyclophosphamide; systemic
12.4
9.9
17
14
L04AA11
ATC
[U] etanercept; parenteral
20.4
9.8
14
7
ZX112
NOMESCO Finland
Subcutaneous
5.3
9.8
29
57
PG5RT
NOMESCO Finland
PTA of arterio-venous shunt for dialysis
55.9
9.7
11
*
XF655
NOMESCO Finland
Measurement of heart muscle perfusion with exercise
4.5
9.7
33
76
3AC01
NOMESCO Finland
NA
11.6
9.6
17
15
L01AA02
ATC
chlorambucil; oral
15.3
9.5
15
10
B01AB10
ATC
tinzaparin; parenteral
2.9
9.5
56
202
ACC51
NOMESCO Finland
Release of median nerve
2.9
9.5
56
202
ND2AA
NOMESCO Finland
Hand and fingers X-ray examination
2.7
9.5
64
251
I25.1
ICD-10 Finland
Atherosclerotic heart disease
1.9
9.5
150
877
TK810
NOMESCO Finland
Hemofiltration
17.9
9.4
14
8
Z49.2
ICD-10 Finland
Other dialysis
12.6
9.4
16
13
B05DB
ATC
Hypertonic solutions
12.6
9.4
16
13
27699
ICD-8 Finland
Amyloidosis
+∞
9.4
9
*
JN1AE
NOMESCO Finland
Ultrasound examination of upper part of abdomen
2.7
9.4
65
257
P01BA02
ATC
hydroxychloroquine; oral
2.6
9.3
69
286
N05CF01
ATC
zopiclone; oral
1.8
9.3
210
1384
H02.1
ICD-10 Finland
Ectropion of eyelid
6.9
9.2
22
33
B01AC04
ATC
clopidogrel; oral
2.2
9.2
104
529
Z01.0
ICD-10 Finland
Examination of eyes and vision
2.2
9.2
104
529
E78.9
ICD-10 Finland
Disorder of lipoprotein metabolism, unspecified
11.7
9.1
16
14
S18
ICPC
Laceration/cut
1.7
9.1
260
1840
L04AC07
ATC
tocilizumab; parenteral
37.2
9.0
11
*
9294
FHL
Endoprosthesis replacement of the entire hip joint (eg Charnley)
6.2
9.0
23
38
C09AA05
ATC
ramipril; oral
1.8
9.0
175
1096
NF1AE
NOMESCO Finland
Hip joint ultrasound examination
4.6
9.0
30
68
JAK10
NOMESCO Finland
Laparotomy and insertion of peritoneal dialysis catheter
18.9
9.0
13
7
FM1CG
NOMESCO Finland
Extensive examination of hear with high intensity magnet
18.9
9.0
13
7
QAJ30
NOMESCO Finland
Other facelift
24.4
8.9
12
5
CBF99
NOMESCO Finland
Other operation for ectropion
24.4
8.9
12
5
X59
ICD-10 Finland
Exposure to unspecified factor
2.0
8.9
118
644
GA4YT
NOMESCO Finland
Puncture of pleura with ultrasound guidance
4.5
8.8
30
69
WX110
NOMESCO Finland
Local anesthesy
1.7
8.8
365
2857
I61.9
ICD-10 Finland
Intracerebral haemorrhage, unspecified
6.1
8.8
23
39
H05BA01
ATC
calcitonin (salmon synthetic); nasal, parenteral
3.6
8.8
38
109
XPX99
NOMESCO Finland
Other diagnostic examination of periferal vessel
2.8
8.8
56
213
9289
FHL
Other measure in this category
50.7
8.7
10
*
WW409
NOMESCO Finland
Other aferesis
50.7
8.7
10
*
M06.0
ICD-10 Finland
Seronegative rheumatoid arthritis
4.6
8.6
29
66
B01AB04
ATC
dalteparin; parenteral
3.3
8.6
42
133
I10
ICD-10 Finland
Essential (primary) hypertension
1.7
8.6
370
2917
G51.0
ICD-10 Finland
Bell palsy
5.3
8.6
25
49
AA1CG
NOMESCO Finland
Extensive MRI examination of brain with high intensity magnet
2.9
8.5
51
186
XF402
NOMESCO Finland
ECG with work load test
2.4
8.5
77
352
NDG74
NOMESCO Finland
Fusion of first IP joint
27.9
8.5
11
*
L01CB
ATC
Podophyllotoxin derivatives
27.9
8.5
11
*
RS221
NOMESCO Finland
NA
7.5
8.5
19
26
A12AA12
ATC
[U] calcium acetate anhydrous; systemic
20.3
8.5
12
6
9503
FHL
Tendon or tendon sheath cleansing surgery (tenosynovectomy)
20.3
8.5
12
6
S97
ICPC
Chronic ulcer skin
3.1
8.5
45
152
A09
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
2.1
8.4
95
483
SPAT1148
SPAT
Treatment of chronic ulcer or burn
2.1
8.4
95
483
A04.7
ICD-10 Finland
Enterocolitis due to Clostridium difficile
4.4
8.4
29
68
NDG30
NOMESCO Finland
Fusion of wrist, total
13.0
8.4
14
11
S01AD03
ATC
aciclovir; ophthalmic
3.8
8.4
34
93
XCW99
NOMESCO Finland
Other investigative procedure of eye
2.2
8.4
86
420
J01DA01
ATC
[U] cefalexin; systemic
1.7
8.4
374
2968
I42.5
ICD-10 Finland
Other restrictive cardiomyopathy
+∞
8.3
8
*
J01MA14
ATC
moxifloxacin; systemic
2.5
8.3
68
295
ZZH31
NOMESCO Finland
Bone allograft, small pieces
9.6
8.3
16
17
TPH07
NOMESCO Finland
Cathetrisation of artery
2.4
8.3
73
329
B01AA03
ATC
warfarin; systemic
1.8
8.2
156
966
CBB20
NOMESCO Finland
Correction of lax skin of eyelid and resection of herniated fat
6.6
8.2
20
31
I61.0
ICD-10 Finland
Intracerebral haemorrhage in hemisphere, subcortical
6.2
8.2
21
35
NF1AA
NOMESCO Finland
Hip X-ray examination
2.4
8.1
72
325
L04AB04
ATC
adalimumab; parenteral
8.3
8.1
17
21
FB1BD
NOMESCO Finland
Extensive CT examination of arteria pulmonalis
2.6
8.1
58
235
CBK11
NOMESCO Finland
Operation for lagophtalmus with implant
33.8
8.1
10
*
L01BB01
ATC
NA
33.8
8.1
10
*
XCK10
NOMESCO Finland
Photography of fundus of eye
2.3
8.1
73
336
R60.0
ICD-10 Finland
Localized oedema
2.2
8.1
80
385
I69.1
ICD-10 Finland
Sequelae of intracerebral haemorrhage
7.4
8.0
18
25
RD210
NOMESCO Finland
NA
7.9
7.9
17
22
JN3AD
NOMESCO Finland
Abdominal CT examination
2.6
7.9
57
232
RS220
NOMESCO Finland
NA
9.6
7.8
15
16
ACC59
NOMESCO Finland
Decompression and freeing of adhesions of peripheral nerve: other or unspecified
3.1
7.8
41
138
TQW99
NOMESCO Finland
Other minor procedure on skin
3.0
7.7
44
155
C08CA01
ATC
amlodipine; oral
1.7
7.7
229
1615
CBN30
NOMESCO Finland
Shortening of canthal ligament
12.0
7.6
13
11
9522
FHL
Synovectomy
25.3
7.6
10
*
D64.9
ICD-10 Finland
Anaemia, unspecified
2.2
7.6
74
353
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
2.5
7.6
58
244
RS222
NOMESCO Finland
NA
9.0
7.6
15
17
XF400
NOMESCO Finland
ECG with 12 standard connections
1.9
7.6
110
620
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
3.8
7.6
30
81
H25.1
ICD-10 Finland
Senile nuclear cataract
1.7
7.4
193
1310
M08.4
ICD-10 Finland
Pauciarticular juvenile arthritis
81.0
7.4
8
*
I42.9
ICD-10 Finland
Cardiomyopathy, unspecified
5.7
7.4
20
36
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
2.3
7.4
70
328
I20.99
ICD-10 Finland
Angina pectoris, unspecified
2.8
7.3
46
172
E89.2
ICD-10 Finland
Postprocedural hypoparathyroidism
+∞
7.3
7
*
SPAT1229
SPAT
Assessment of need for aid
2.4
7.3
60
264
H26.2
ICD-10 Finland
Complicated cataract
5.9
7.3
19
33
EB1HA
NOMESCO Finland
Panorama tomography of teeth and jaws or similar X-ray examination
1.6
7.3
216
1520
201
Kela drug reimbursment
Chronic cardiac insufficiency
2.7
7.3
47
181
CBF10
NOMESCO Finland
Shortening of canthal ligaments and tarsal plate for ectropion
16.0
7.2
11
7
H02AB07
ATC
prednisone; oral
2.0
7.2
102
568
C09CA01
ATC
losartan; oral
1.7
7.2
156
1003
FM1BE
NOMESCO Finland
Cardiac ultrasound examination through oesophagus
2.8
7.2
43
158
C10AA01
ATC
simvastatin; oral
1.6
7.2
264
1965
NDG77
NOMESCO Finland
Other excision, reconstruction or fusion of joint of first finger
30.4
7.2
9
*
196
Kela drug reimbursment
Paricalcitol and cinacalcet
30.4
7.2
9
*
ZST00
NOMESCO Finland
Procedure related to previous procedure classified in chapter T
30.4
7.2
9
*
PG5DE
NOMESCO Finland
Ultrasound examination of injection gate to artery or vein with Doppler method
30.4
7.2
9
*
WD515
NOMESCO Finland
Demanding therapy of malignancy with enzyme inhibitors and similar treatments
20.3
7.1
10
5
N18.5
ICD-10 Finland
Chronic kidney disease, stage 5
20.3
7.1
10
5
AA1BG
NOMESCO Finland
Standard MRI examination of brain with high intensity magnet
2.6
7.1
52
212
G45.9
ICD-10 Finland
Transient cerebral ischaemic attack, unspecified
2.5
7.1
56
241
J01DB01
ATC
cefalexin; oral
1.7
7.1
466
4003
M01CB03
ATC
auranofin; oral
10.2
7.1
13
13
M05
ICD-10 Finland
Seropositive rheumatoid arthritis
7.1
7.0
16
23
H02AB09
ATC
hydrocortisone; systemic
5.6
7.0
19
35
XX9XE
NOMESCO Finland
Other ultrasound examination
7.7
6.9
15
20
E87.6
ICD-10 Finland
Hypokalaemia
7.7
6.9
15
20
L95.9
ICD-10 Finland
Vasculitis limited to skin, unspecified
14.0
6.9
11
8
H26.3
ICD-10 Finland
Drug-induced cataract
14.0
6.9
11
8
Z95.0
ICD-10 Finland
Presence of electronic cardiac devices
2.8
6.9
44
167
M05.3
ICD-10 Finland
Rheumatoid arthritis with involvement of other organs and systems
40.5
6.8
8
*
CBH25
NOMESCO Finland
Tarsorrhaphy
40.5
6.8
8
*
Z01.8
ICD-10 Finland
Other specified special examinations
1.8
6.8
125
764
UKC02
NOMESCO Finland
Cystoscopy
1.8
6.8
117
700
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
1.9
6.7
96
536
NH3DA
NOMESCO Finland
Bilateral foot X-ray examination
4.5
6.7
22
50
JN4AD
NOMESCO Finland
Body CT examination
2.4
6.7
54
236
N02AA05
ATC
oxycodone; systemic
1.9
6.7
103
591
ZZC00
NOMESCO Finland
Graft of fascia
22.8
6.7
9
*
PBL09
NOMESCO Finland
Construction of arteriovenous fistula from brachial artery
22.8
6.7
9
*
H02AB08
ATC
triamcinolone; systemic
22.8
6.7
9
*
K65.0
ICD-10 Finland
Acute peritonitis
6.0
6.6
17
29
NG1AE
NOMESCO Finland
Knee joint ultrasound exmination
7.9
6.6
14
18
WZC00
NOMESCO Finland
Planning of intervention or health care consultation
1.7
6.6
180
1230
H18.4
ICD-10 Finland
Corneal degeneration
12.4
6.6
11
9
D06BB04
ATC
podophyllotoxin; topical
3.6
6.6
28
81
UJF32
NOMESCO Finland
Coloscopy
1.7
6.5
157
1035
WX408
NOMESCO Finland
General anesthesy, balanced
1.7
6.5
153
1005
Z96.1
ICD-10 Finland
Presence of intraocular lens
1.9
6.5
98
559
E03.9
ICD-10 Finland
Hypothyroidism, unspecified
2.1
6.5
71
357
N10
ICD-10 Finland
Acute tubulo-interstitial nephritis
2.0
6.5
83
445
M80.9
ICD-10 Finland
Unspecified osteoporosis with pathological fracture
4.8
6.5
20
43
212
Kela drug reimbursment
Gout
4.1
6.5
23
57
SPAT1230
SPAT
Aid fitting and borrowing and monitoring of use
1.9
6.4
103
600
QAJ15
NOMESCO Finland
Browlift using video-endoscope
70.5
6.4
7
*
M05.2
ICD-10 Finland
Rheumatoid vasculitis
70.5
6.4
7
*
M43.4
ICD-10 Finland
Other recurrent atlantoaxial subluxation
70.5
6.4
7
*
J05AB11
ATC
valaciclovir; oral
2.1
6.4
75
388
NHG24
NOMESCO Finland
Fusion of subtalar joint and between bones of ankle
14.5
6.4
10
7
TK820
NOMESCO Finland
Peritoneal dialysis
14.5
6.4
10
7
NGB40
NOMESCO Finland
Primary total prosthetic replacement of knee joint with patellar part - sliding prosthesis
3.3
6.4
30
94
TQW40
NOMESCO Finland
Remowal of suture of skin
2.5
6.4
48
202
L04AB01
ATC
etanercept; parenteral
5.6
6.3
17
31
N19
ICPC
Speech disorder
11.2
6.3
11
10
NHG20
NOMESCO Finland
Fusion of talocrural joint
9.4
6.3
12
13
NG1AA
NOMESCO Finland
Knee X-ray examination without contrast
2.0
6.3
78
413
N084, E853
ICD-10 Finland
NA
+∞
6.3
6
*
L03AA02
ATC
filgrastim; parenteral
3.7
6.2
25
69
L04AA17
ATC
[U] adalimumab; parenteral
27.0
6.2
8
*
TCG00
NOMESCO Finland
Protection of cornea and sclera with soft lens
27.0
6.2
8
*
V03AE03
ATC
lanthanum carbonate; oral
27.0
6.2
8
*
J20.9
ICD-10 Finland
Acute bronchitis, unspecified
1.8
6.2
101
590
E0000UV
ATC
NA
1.6
6.2
222
1624
H03AA01
ATC
levothyroxine sodium; systemic
1.7
6.2
128
809
B80
ICPC
Iron deficiency anaemia
5.8
6.2
16
28
FPE20
NOMESCO Finland
Implantation of transvenous cardiac pacemaker with atrial and ventricular electrodes
2.9
6.1
36
131
NH1AA
NOMESCO Finland
Ankle X-ray examination without contrast
2.6
6.1
43
173
R11
ICD-10 Finland
Nausea and vomiting
2.4
6.1
49
212
104
Kela drug reimbursment
Thyroid insufficiency
2.5
6.1
46
194
E000001
ATC
NA
1.7
6.1
122
762
9273
FHL
Other surgery for toe deformity or pain condition, e.g., Morton, hammer toe
6.8
6.1
14
21
S01XA18
ATC
ciclosporin; ophthalmic
10.1
6.0
11
11
Mortality – FinRegistry
↥This endpoint is excluded from FinRegistry analyses (omitted endpoint).
Relationships between endpoints
↥Index endpoint: E4_AMYLOIDOSIS – Amyloidosis
GWS hits: -
This endpoint is excluded from FinRegistry analyses (omitted endpoint).