Ischemic heart diseases

I9_ISCHHEART

coronary thrombosis: Coagulation of blood in any of the coronary vessels. The presence of a blood clot (thrombus) often leads to myocardial infarction.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 I20-I25
Cause of death: ICD-10 I20-I25

47365

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

47365

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Check minimum number of events None

47365

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I9_ISCHHEART

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Ischemic heart diseases based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 49030 17060 31970
Unadjusted prevalence (%) 15.89 9.83 23.68
Mean age at first event (years) 63.94 65.14 63.29

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.66 [3.37, 3.98] <1e-100 13939
15 years 0.01 2.11 [1.93, 2.30] 1.0e-65 5458
5 years 0.00 3.58 [3.30, 3.88] <1e-100 2885
1 year 0.00 26.25 [23.23, 29.67] <1e-100 3979

Correlations

Index endpoint: I9_ISCHHEART – Ischemic heart diseases
GWS hits: 39

Survival analyses between endpoints

Plot

before Ischemic heart diseases
after Ischemic heart diseases

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Drugs most likely to be purchased after Ischemic heart diseases