Myocardial infarction

I9_MI

myocardial infarction: Gross necrosis of the myocardium, as a result of interruption of the blood supply to the area, as in coronary thrombosis.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 I21, I22
Hospital discharge: ICD-9 410
Hospital discharge: ICD-8 410
Cause of death: ICD-10 I21, I22
Cause of death: ICD-9 410
Cause of death: ICD-8 410

21098

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

21098

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Check minimum number of events None

21098

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Include endpoints None

21098

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I9_MI

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Myocardial infarction based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 20404 5601 14803
Unadjusted prevalence (%) 6.61 3.23 10.96
Mean age at first event (years) 65.93 69.22 64.68

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 4.08 [3.64, 4.57] <1e-100 7503
15 years 0.01 1.93 [1.73, 2.15] 1.2e-32 2533
5 years 0.00 3.59 [3.27, 3.95] <1e-100 1630
1 year 0.00 27.52 [24.50, 30.90] <1e-100 2683

Cumulative Incidence

Correlations

Index endpoint: I9_MI – Myocardial infarction
GWS hits: 23

Survival analyses between endpoints

Plot

before Myocardial infarction
after Myocardial infarction

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Drugs most likely to be purchased after Myocardial infarction