This is a non-core endpoint: only basic statistics are computed.

Dental invagination

K11_DENTAL_INVAGINAT

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — K00.25 Cause of death: ICD-10 — K00.25 2 out of 7 registries used, show all original rules.	14
4. Check minimum number of events None	14
5. Include endpoints None	14
6. Filter based on genotype QC (FinnGen only)	14

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze: DF7

NAME	K11_DENTAL_INVAGINAT
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	K0025
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	K0025
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Dental invagination based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	193	94	98
Only index persons	155	80	75
Unadjusted period prevalence (%)
Whole population	0.00	0.00	0.00
Only index persons	0.00	0.00	0.00
Median age at first event (years)
Whole population	12.53	13.32	11.59
Only index persons	14.93	15.94	13.85

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	14	6	8
Unadjusted period prevalence (%)	0.00	0.00	0.00
Median age at first event (years)	33.64	41.68	27.61

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(1761868) Lipid panel - Serum or Plasma

3.42

1.48

2.1

2.6

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

3.30

1.44

4.3

5.1

—

(3026008) Bacteria identified in Urine by Culture

3.30

1.27

4.2

3.0

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

3.12

1.20

1.0

2.6

53.4

62.2

u/l

—

(3033658) Prothrombin time (PT) actual/Normal

2.80

0.87

2.6

9.6

99.4

90.5

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

2.21

0.74

3.4

4.6

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

0.00

0.66

0.0

1.8

—

1.1

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

2.18

0.60

5.8

11.0

6.5

mmol/l

—

(3037467) Urinalysis macro (dipstick) panel - Urine

1.90

0.40

1.8

3.4

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

1.60

0.28

2.4

3.3

85.0

73.7

nmol/l

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.22

0.0

1.8

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

0.00

0.22

0.0

1.8

—

(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction

0.00

0.22

0.0

5.1

—

256.5

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

13.3

—

1.3

—

(3001604) Monocytes [#/volume] in Blood

1.23

0.11

2.2

6.5

0.7

0.5

e9/l

—

(3006315) Basophils [#/volume] in Blood

1.23

0.11

2.0

6.6

0.1

0.0

e9/l

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

1.33

0.11

4.6

8.5

4.1

4.0

e9/l

—

(3019198) Lymphocytes [#/volume] in Blood

1.19

0.11

2.3

6.6

2.4

1.9

e9/l

—

(3013115) Eosinophils [#/volume] in Blood

1.16

0.11

2.3

6.7

0.2

e9/l

—

(3044889) 12 lead EKG panel

1.09

0.00

2.5

2.7

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

0.00

0.0

3.4

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.0

—

(3021589) Normoblasts [#/volume] in Blood

1.06

0.00

8.0

8.1

0.0

e9/l

—

(3016879) Cocaine [Presence] in Urine

0.00

0.0

1.0

—

(3012336) Haptoglobin [Mass/volume] in Serum or Plasma

0.00

0.0

2.4

—

1.5

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

0.00

0.0

1.4

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

0.0

1.9

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

0.00

0.0

1.4

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

2.0

—

(1002224) Polysomnography panel

0.00

0.0

1.2

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

0.0

1.2

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.6

—

(3028300) Cannabinoids [Presence] in Urine

0.00

0.0

1.0

—

(3020961) Endomysium IgA Ab [Titer] in Serum

0.00

0.0

1.2

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.0

1.3

—

(3027944) Amphetamines [Presence] in Urine

0.00

0.0

1.0

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.00

0.0

1.0

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

0.00

0.0

1.6

—

(3010521) Mycoplasma pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.3

—

(40768443) Skin Pathology biopsy report

0.00

0.0

1.0

—

(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum

0.00

0.0

3.6

—

(3035637) Corticotropin [Mass/volume] in Plasma

0.00

0.0

1.2

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.0

1.5

—

(3000764) Benzodiazepines [Presence] in Urine

0.00

0.0

1.0

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

0.00

0.0

1.6

—

(3029634) Reagin Ab [Titer] in Serum by VDRL

0.00

0.0

2.6

—

(3022145) Colonoscopy Study observation

0.00

0.0

1.4

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

0.00

0.0

10.0

—

4.6

—

(42529406) Shigella sp [Presence] in Stool by Culture

0.00

0.0

1.6

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

0.00

0.0

15.3

—

82.9

—

(3019060) Gas panel - Arterial blood

0.00

0.0

3.8

—

(3011288) Drugs identified in Urine by Screen method

0.00

0.0

1.2

—

(3027008) Opiates [Presence] in Urine

0.00

0.0

1.0

—

(3005033) Fetal Nuchal fold Thickness US

0.00

0.0

1.3

—

Mortality – FinRegistry

↥

Association

Association between endpoint K11_DENTAL_INVAGINAT and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have K11_DENTAL_INVAGINAT.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: K11_DENTAL_INVAGINAT – Dental invagination

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Dental invagination

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints