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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Hypervitaminosis D

E4_HYPER_VIT_D

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 E67.3
  • Hospital discharge: ICD-9 2784
  • Hospital discharge: ICD-8 2782
  • Cause of death: ICD-10 E67.3
  • Cause of death: ICD-9 2784
  • Cause of death: ICD-8 2782

2 out of 7 registries used, show all original rules.

12

4. Check minimum number of events

None

12

5. Include endpoints

None

12

6. Filter based on genotype QC (FinnGen only)

12

Control definitions (FinnGen only)

Control exclude
E4_OBESITY_HYPER

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
E67
Name in latin
Hypervitaminosis D

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 77 52 24
Only index persons 61 47 14
Unadjusted period prevalence (%)
Whole population 0.00 0.00 0.00
Only index persons 0.00 0.00 0.00
Median age at first event (years)
Whole population 59.51 64.50 47.84
Only index persons 61.22 64.98 48.60

-FinnGen-

Key figures

All Female Male
Number of individuals 12 10 -
Unadjusted period prevalence (%) 0.00 0.00 -
Median age at first event (years) 60.49 59.20 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3012095) Magnesium [Moles/volume] in Serum or Plasma
5
19
3.75
1.37
4.2
1.9
mmol/l
0.8
0.8
—
5
19
(3013512) EKG study
6
30
2.97
1.06
2.8
3.3
—
—
—
0
0
(36304419) Bacteria [Presence] in Urine
6
32
2.73
0.99
3.5
2.5
—
—
—
0
0
(3044889) 12 lead EKG panel
5
77
0.40
0.68
6.4
3.8
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
12
98
+∞
0.67
19.8
15.2
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
5
30
2.13
0.52
5.8
4.6
—
—
—
0
0
(3021589) Normoblasts [#/volume] in Blood
6
42
1.85
0.45
16.0
13.2
e9/l
0.0
0.0
—
6
37
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
0
15
0.00
0.45
0.0
1.4
—
—
—
0
0
(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma
12
106
+∞
0.44
9.6
11.7
u/l
22.5
25.3
0.53
12
101
(3023103) Potassium [Moles/volume] in Serum or Plasma
12
103
+∞
0.44
24.4
16.2
mmol/l
3.9
4.0
0.75
12
97
(3020564) Creatinine [Moles/volume] in Serum or Plasma
12
103
+∞
0.44
22.2
18.4
umol/l
99.5
70.6
0.99
12
103
(3019550) Sodium [Moles/volume] in Serum or Plasma
12
103
+∞
0.44
23.8
16.4
mmol/l
139.9
139.7
0.10
12
97
(3000494) Fungus identified in Specimen by Culture
0
17
0.00
0.44
0.0
1.2
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
0
10
0.00
0.22
0.0
1.3
—
—
—
0
0
(3000963) Hemoglobin [Mass/volume] in Blood
12
108
+∞
0.22
26.8
24.1
g/l
129.8
134.6
0.42
12
108
(3024731) MCV [Entitic volume]
12
108
+∞
0.22
26.7
23.8
fl
91.6
91.2
0.13
12
108
(3035941) MCH [Entitic mass]
12
108
+∞
0.22
26.7
23.8
pg
30.4
30.3
0.09
12
108
(3042936) Bacteria identified in Isolate by Culture
0
13
0.00
0.22
0.0
1.8
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
5
41
1.37
0.12
4.6
3.0
—
—
—
0
0
(3013826) Glucose [Moles/volume] in Serum or Plasma
6
60
1.00
0.00
3.0
4.5
mmol/l
5.5
6.3
—
6
55
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis
0
5
0.00
0.00
0.0
1.0
—
9.3
—
0
5
(3000492) Spirometry study
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3014111) Lactate [Moles/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
3.0
—
1.0
—
0
8
(3019060) Gas panel - Arterial blood
0
7
0.00
0.00
0.0
2.3
—
—
—
0
0
(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
2.2
—
356.8
—
0
6
(3008898) HLA-B27 [Presence]
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3013650) Neutrophils [#/volume] in Blood by Automated count
6
58
1.07
0.00
11.3
12.6
e9/l
3.9
4.6
—
6
52
(4035726)
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(4010399)
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
2.5
—
9.0
—
0
6
(3032836) C peptide [Moles/volume] in Serum or Plasma --fasting
0
5
0.00
0.00
0.0
1.0
—
0.7
—
0
5
(3005702) Mycobacterium sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(3014218) Bicarbonate [Moles/volume] standard in Arterial blood
0
5
0.00
0.00
0.0
3.4
—
22.5
—
0
5
(40768443) Skin Pathology biopsy report
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3021387) Prolactin [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.0
—
532.2
—
0
6
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
5
48
1.07
0.00
3.8
3.5
—
—
—
0
0
(44816559) Phosphatidylethanol [Mass/volume] in Blood
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay
0
5
0.00
0.00
0.0
1.4
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
0
9
0.00
0.00
0.0
2.0
—
—
—
0
0
(3037551) Cancer Ag 125 [Units/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
1.5
—
22.3
—
0
6
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint E4_HYPER_VIT_D and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have E4_HYPER_VIT_D.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: E4_HYPER_VIT_D – Hypervitaminosis D

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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