No definition available.
Endpoint definition
↥
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
520210 |
1. Apply sex-specific ruleNone |
520210 |
2. Check conditionsNone |
520210 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
94 |
4. Check minimum number of eventsNone |
94 |
5. Include endpoints |
113 |
6. Filter based on genotype QC (FinnGen only) |
113 |
Control definitions (FinnGen only)
- Control exclude
- E4_OBESITY_HYPER
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Other hyperalimentation
based on the number of shared cases.
Similar with more cases:
- Obesity and other hyperalimentation
- Endocrine, nutritional and metabolic diseases
- Any event in hilmo or specialist outpatient
Similar with less cases:
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 767 | 460 | 298 |
| Only index persons | 615 | 384 | 231 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.01 |
| Median age at first event (years) | |||
| Whole population | 49.68 | 48.81 | 50.63 |
| Only index persons | 48.07 | 47.96 | 48.24 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 113 | 74 | 39 |
| Unadjusted period prevalence (%) | 0.02 | 0.03 | 0.02 |
| Median age at first event (years) | 50.61 | 47.99 | 55.57 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS (R11)
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 107
- Matched controls
- 1071
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
E68
ICD-10 Finland
Sequelae of hyperalimentation
+∞
68.2
58
*
E66.8
ICD-10 Finland
Other obesity
225.2
32.7
32
*
E66.01
ICD-10 Finland
Obesity due to excess calories
46.8
27.6
33
10
E66.00
ICD-10 Finland
Metabolic syndrome
91.2
20.6
22
*
E66.9
ICD-10 Finland
Obesity, unspecified
71.3
16.3
18
*
QBJ30
NOMESCO Finland
Correction of abdominal apron
+∞
16.0
15
*
E67.3
ICD-10 Finland
Hypervitaminosis D
+∞
11.7
11
*
JDF11
NOMESCO Finland
Laparoscopic gastric bypass
+∞
10.6
10
*
Z71.3
ICD-10 Finland
Dietary counselling and surveillance
24.4
9.6
13
6
T82
ICPC
Obesity
15.6
9.5
15
11
E67.8
ICD-10 Finland
Other specified hyperalimentation
+∞
9.5
9
*
E66.2
ICD-10 Finland
Extreme obesity with alveolar hypoventilation
+∞
9.5
9
*
103
Kela drug reimbursment
Diabetes, insulin-treated
4.1
9.2
43
152
27799
ICD-8 Finland
Obesity not specified as of endocrine origin
+∞
8.4
8
*
E67.2
ICD-10 Finland
Megavitamin-B6syndrome
+∞
8.4
8
*
27899
ICD-8 Finland
Other hyperalimentation, Other and unspecified
+∞
8.4
8
*
G47.3
ICD-10 Finland
Sleep apnoea
4.4
8.0
31
91
E11.9
ICD-10 Finland
Type 2 diabetes mellitus, without complications
3.8
7.7
37
131
A10BA02
ATC
metformin; oral
3.6
7.6
42
164
SPAT1262
SPAT
Handing over of treatment supplies
4.0
7.1
30
95
215
Kela drug reimbursment
Diabetes, non-insulin-treated
3.5
6.9
36
135
JKA21
NOMESCO Finland
Laparoscopic cholecystectomy
5.0
6.8
22
53
285
Kela drug reimbursment
Dulaglutide, exenatide, liraglutide, lixisenatide and semaglutide (adults)
16.2
6.0
9
6
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma
72
349
3.93
11.37
3.8
2.2
nmol/l
76.6
80.6
0.49
64
310
(3024561) Albumin [Mass/volume] in Serum or Plasma
72
370
3.61
9.97
5.1
4.3
g/l
35.5
35.8
0.15
65
351
(43054903) Holo-transcobalamin II [Moles/volume] in Serum
68
341
3.50
9.71
2.7
1.8
pmol/l
112.5
95.6
1.44
42
164
(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma
49
202
3.52
9.56
2.6
1.8
mg/l
3.0
3.1
0.11
41
178
(3019309) Folate [Moles/volume] in Red Blood Cells
41
171
3.19
7.59
2.1
1.7
nmol/l
1124.3
1304.2
0.50
32
128
(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum
12
21
6.27
6.74
1.7
1.0
—
—
—
0
0
(3009508) Creatinine [Moles/volume] in Urine
49
242
2.81
6.55
4.0
2.7
mmol/l
7.5
7.3
0.04
37
205
(3020682) Albumin/Creatinine [Ratio] in Urine
48
237
2.78
6.39
4.9
3.5
mg/mmol
6.7
6.2
0.05
28
148
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
70
429
2.66
5.93
10.5
6.3
mmol/l
1.2
1.2
0.32
60
351
(3019225) pH of Specimen
21
70
3.46
5.44
7.5
5.4
—
—
—
0
0
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
67
419
2.47
5.19
4.7
4.1
—
—
—
0
0
(3021960) Folate [Moles/volume] in Serum or Plasma
42
212
2.56
5.18
1.9
1.5
nmol/l
21.3
21.9
0.08
35
178
(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma
38
184
2.60
5.09
2.0
1.7
pmol/l
517.8
477.0
0.19
31
155
(3012516) Albumin [Mass/volume] in Urine
43
222
2.51
5.04
4.1
2.9
mg/l
63.4
332.7
0.43
24
137
(3044640) Blood type and Crossmatch panel - Blood
50
282
2.39
4.78
2.9
2.4
—
—
—
0
0
(3004588) Protein electrophoresis panel - Serum or Plasma
18
61
3.32
4.52
1.1
2.1
—
—
—
0
0
(3026782) Osmolality of Urine
36
180
2.47
4.44
2.4
2.6
mosm/kgh2o
534.8
545.1
0.07
29
153
(3015377) Calcium [Moles/volume] in Serum or Plasma
51
303
2.25
4.21
2.5
3.4
mmol/l
2.3
2.4
1.57
44
270
(3017732) Neutrophils [#/volume] in Blood
19
71
3.01
4.07
2.8
2.5
e9/l
4.1
3.6
0.53
12
53
(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma
39
213
2.27
3.89
1.6
1.7
mg/l
0.9
1.1
0.29
29
168
(3032080) INR in Blood by Coagulation assay
56
359
2.11
3.70
4.7
7.2
inr
1.1
1.2
0.22
15
117
(3012544) pH of Venous blood
18
69
2.91
3.68
2.9
4.1
—
—
—
0
0
(3022313) Gas panel - Capillary blood
12
36
3.61
3.59
7.5
4.0
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
17
64
2.95
3.59
1.6
1.6
—
—
—
0
0
(3002582) Erythrocytes [#/volume] in Urine
45
270
2.11
3.49
4.0
3.0
e6/l
45.0
268.1
0.47
35
213
(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence
9
18
5.33
3.45
1.2
1.1
—
—
—
0
0
(40768797) Stomach Pathology biopsy report
27
132
2.37
3.43
1.1
1.3
—
—
—
0
0
(3007853) Bacteria identified in Skin by Aerobe culture
22
99
2.52
3.32
4.4
1.6
—
—
—
0
0
(3001122) Ferritin [Mass/volume] in Serum or Plasma
57
379
2.02
3.31
4.1
2.7
ug/l
103.8
102.1
0.03
50
344
(46236098) ABO and Rh group [Type] in Blood by Confirmatory method
37
210
2.13
3.29
2.8
2.3
—
—
—
0
0
(3009445) Proteinase 3 Ab [Units/volume] in Serum
13
45
3.13
3.14
1.5
1.1
—
—
—
0
0
(3016251) Hemoglobin.gastrointestinal [Presence] in Stool
12
40
3.24
3.07
3.2
2.3
—
—
—
0
0
(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count
49
317
1.96
3.01
4.1
3.0
—
—
—
0
0
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
91
731
2.26
3.00
9.7
7.8
u/l
83.8
76.5
0.95
91
685
(3030467) Casts [#/volume] in Urine by Automated count
41
252
1.98
2.90
4.3
2.8
e6/l
0.1
0.5
1.86
31
195
(3013826) Glucose [Moles/volume] in Serum or Plasma
70
517
1.93
2.85
5.5
4.7
mmol/l
6.8
6.6
0.37
70
473
(3037467) Urinalysis macro (dipstick) panel - Urine
80
619
2.00
2.82
5.3
4.2
—
—
—
0
0
(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count
24
121
2.25
2.82
3.7
2.7
e6/l
5.1
3.0
0.27
12
67
(3002030) Lymphocytes/100 leukocytes in Blood
62
442
1.89
2.79
7.0
6.1
%
27.0
27.7
0.22
57
410
(3018677) aPTT in Platelet poor plasma by Coagulation assay
26
138
2.15
2.70
2.2
1.8
s
29.4
29.6
0.05
26
132
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
86
688
2.05
2.69
5.1
4.0
pmol/l
14.7
14.8
0.14
74
625
(3023368) Bacteria identified in Blood by Culture
39
242
1.93
2.65
5.4
4.5
—
—
—
0
0
(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma
21
103
2.28
2.62
5.4
4.5
%
34.4
33.7
0.12
15
67
(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence
5
7
7.40
2.57
1.2
1.0
—
—
—
0
0
(3007164) IgA [Mass/volume] in Serum or Plasma
33
197
1.95
2.49
1.7
1.4
g/l
2.3
2.6
0.39
23
118
(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis
10
34
3.13
2.48
1.0
1.4
—
—
—
0
0
(3013512) EKG study
40
257
1.86
2.42
5.4
3.8
—
—
—
0
0
(3037522) Nuclear Ab [Titer] in Serum
22
115
2.13
2.36
1.6
1.3
titre
128.0
391.5
—
5
33
(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma
39
251
1.85
2.33
2.7
3.1
ng/l
1163.5
1444.3
0.23
28
211
(3022145) Colonoscopy Study observation
20
101
2.19
2.33
1.2
1.3
—
—
—
0
0
(3021901) Oxygen saturation in Capillary blood
6
13
4.81
2.30
3.2
2.8
—
—
—
0
0
(3000067) Parathyrin.intact [Mass/volume] in Serum or Plasma
15
67
2.43
2.29
3.9
3.7
ng/l
65.6
78.9
—
10
59
(3018095) Leukocytes [#/volume] in Urine
47
322
1.79
2.29
4.7
3.4
e6/l
45.8
63.5
0.28
35
229
(3004410) Hemoglobin A1c/Hemoglobin.total in Blood
97
829
2.20
2.28
8.4
5.2
mmol/mol
41.9
39.5
1.34
88
781
(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum
35
221
1.85
2.21
1.3
1.2
u/ml
0.5
0.8
—
9
55
(3042936) Bacteria identified in Isolate by Culture
23
126
2.04
2.19
2.7
1.8
—
—
—
0
0
(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection
12
49
2.62
2.18
1.5
1.6
—
—
—
0
0
(3028026) IgM [Mass/volume] in Serum or Plasma
14
62
2.44
2.18
1.9
1.3
g/l
1.3
1.2
0.08
14
53
(3020961) Endomysium IgA Ab [Titer] in Serum
11
43
2.73
2.17
1.0
1.1
—
—
—
0
0
(3026493) Urate [Moles/volume] in Serum or Plasma
36
231
1.82
2.16
2.8
3.1
umol/l
347.5
4627.0
1.06
27
198
(3017895) Helicobacter pylori Ab [Units/volume] in Serum
9
31
3.06
2.12
1.1
1.5
—
—
—
0
0
(3025941) Bacteria identified in Stool by Culture
14
63
2.40
2.11
1.6
1.3
—
—
—
0
0
(42870588) Differential panel, method unspecified - Blood
43
298
1.72
1.96
6.4
5.4
—
—
—
0
0
(3000991) Gas panel - Venous blood
12
52
2.46
1.95
8.9
10.5
—
—
—
0
0
(3006315) Basophils [#/volume] in Blood
61
465
1.68
1.95
6.2
5.7
e9/l
0.0
0.0
0.70
52
406
(36304419) Bacteria [Presence] in Urine
38
255
1.74
1.94
4.5
2.7
—
—
—
0
0
(3023511) Choriogonadotropin [Units/volume] in Urine
6
17
3.66
1.86
1.2
1.0
—
—
—
0
0
(3001604) Monocytes [#/volume] in Blood
60
462
1.64
1.79
6.3
5.7
e9/l
0.6
0.6
0.30
52
400
(3006418) Campylobacter sp identified in Tissue by Organism specific culture
9
36
2.63
1.78
1.7
1.2
—
—
—
0
0
(42529406) Shigella sp [Presence] in Stool by Culture
9
36
2.63
1.78
1.7
1.2
—
—
—
0
0
(3014765) Yersinia sp identified in Stool by Organism specific culture
9
36
2.63
1.78
1.7
1.2
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
96
840
1.95
1.76
21.4
13.5
ml/min/173m2
79.1
81.4
0.37
85
697
(3052851) Hemolysis interference index of Serum or Plasma
7
24
3.04
1.75
5.9
3.1
—
—
—
0
0
(3026389) Candida sp identified in Specimen by Organism specific culture
5
13
3.97
1.73
1.4
1.2
—
—
—
0
0
(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count
23
137
1.85
1.72
3.9
2.4
e6/l
0.8
1.0
0.14
11
81
(3013115) Eosinophils [#/volume] in Blood
61
476
1.61
1.70
6.4
5.8
e9/l
0.2
0.2
0.46
53
421
(3013139) Helicobacter pylori Ag [Presence] in Stool
11
49
2.38
1.69
1.5
1.3
—
—
—
0
0
(3023520) Reticulocytes [#/volume] in Blood
14
70
2.14
1.67
2.3
3.0
e9/l
75.0
67.8
—
9
54
(3038515) Glucose [Moles/volume] in Venous blood
6
20
3.11
1.60
2.3
2.3
mmol/l
6.1
7.3
—
6
20
(3019198) Lymphocytes [#/volume] in Blood
60
475
1.56
1.52
6.3
5.7
e9/l
1.9
1.8
0.39
52
422
(3015736) pH of Urine
46
344
1.57
1.49
3.5
3.8
—
—
—
0
0
(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma
47
354
1.56
1.47
5.1
4.1
ng/l
63.9
30.8
0.48
35
240
(1761482) Bacteria [#/volume] in Urine by Culture
6
22
2.82
1.45
4.5
4.0
—
—
—
0
0
(36305247) Microscopic observation [Identifier] in Isolate by Gram stain
6
22
2.82
1.45
1.5
1.2
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
9
41
2.30
1.40
4.1
3.2
—
—
—
0
0
(3006184) Hemoglobin [Mass/volume] in Capillary blood
6
23
2.70
1.38
2.8
2.3
g/l
135.0
126.7
—
6
15
(3013327) Hepatitis A virus IgM Ab [Presence] in Serum
5
17
3.03
1.37
1.2
1.0
—
—
—
0
0
(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma
5
18
2.86
1.30
6.2
1.8
—
—
—
0
0
(1616796) Gas panel - Central venous blood
5
18
2.86
1.30
3.4
2.7
—
—
—
0
0
(40769539) Bacteria identified based on 16S rRNA gene [Identifier] in Specimen by Sequencing
5
18
2.86
1.30
1.0
1.9
—
—
—
0
0
(3026008) Bacteria identified in Urine by Culture
37
271
1.54
1.28
2.4
2.8
—
—
—
0
0
(3014218) Bicarbonate [Moles/volume] standard in Arterial blood
8
36
2.31
1.27
9.4
10.5
mmol/l
24.6
24.6
—
8
31
(3004716) Salmonella sp identified in Stool by Organism specific culture
11
56
2.07
1.27
1.6
1.4
—
—
—
0
0
(3034770) Mitochondria Ab [Titer] in Serum
6
25
2.48
1.26
1.2
1.2
—
—
—
0
0
(4035726)
14
79
1.88
1.23
1.1
1.2
—
—
—
0
0
(3019832) Treponema pallidum Ab [Presence] in Serum
15
87
1.83
1.22
1.5
1.7
—
—
—
0
0
(3016650) Hepatitis A virus Ab [Presence] in Serum
5
20
2.57
1.16
1.4
1.0
—
—
—
0
0
(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood
8
41
2.02
1.11
3.5
3.3
%
53.3
46.4
—
8
41
(3049717) Cytology report of Urine Cyto stain
7
32
2.26
1.10
2.9
2.3
—
—
—
0
0
(3023939) Sjogrens syndrome-A extractable nuclear Ab [Units/volume] in Serum
5
21
2.44
1.10
1.2
1.5
—
46.3
—
0
5
(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection
5
21
2.44
1.10
1.8
1.7
—
—
—
0
0
(3004119) Hemoglobin [Mass/volume] in Venous blood
9
46
2.04
1.06
2.1
2.8
g/l
124.0
132.1
—
9
46
(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection
10
53
1.97
1.05
1.3
1.2
—
—
—
0
0
(3033319) Streptococcus pyogenes Ag [Presence] in Throat
14
84
1.76
1.03
1.2
1.4
—
—
—
0
0
(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection
7
36
2.01
0.99
2.0
2.1
—
—
—
0
0
(40762366) Oxygen capacity [Volume Fraction] in Arterial blood
7
37
1.95
0.96
10.9
6.2
—
—
—
0
0
(3018418) pH of Serum or Plasma
36
279
1.43
0.92
8.5
4.0
ph
7.4
7.4
—
9
60
(3003694) ABO and Rh group [Type] in Blood
32
244
1.43
0.89
1.5
1.4
—
—
—
0
0
(3021601) Nitrite [Presence] in Urine by Test strip
53
442
1.37
0.88
5.6
5.2
estimate
0.0
0.0
0.00
11
102
(3013650) Neutrophils [#/volume] in Blood by Automated count
63
541
1.37
0.87
8.3
10.2
e9/l
4.7
4.0
1.49
57
474
(3009201) Thyrotropin [Units/volume] in Serum or Plasma
91
832
1.48
0.86
6.6
4.6
mu/l
1.9
1.9
0.01
83
753
(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting
93
854
1.50
0.86
5.1
3.8
mmol/l
1.5
1.2
1.06
82
786
(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum
12
73
1.72
0.85
2.4
2.3
—
16.8
—
0
6
(3035350) Ketones [Presence] in Urine by Test strip
53
445
1.36
0.84
3.6
4.0
estimate
0.0
0.0
0.00
12
100
(21494755) Public health laboratory ask at order entry panel
5
98
0.49
0.82
1.2
1.3
—
—
—
0
0
(3009542) Hematocrit [Volume Fraction] of Blood
91
835
1.46
0.82
24.0
13.7
%
38.8
40.1
0.65
62
625
(3016879) Cocaine [Presence] in Urine
6
33
1.86
0.80
2.3
1.3
—
—
—
0
0
(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection
6
33
1.86
0.80
1.7
1.9
—
—
—
0
0
(40761511) CBC panel - Blood by Automated count
101
948
1.62
0.79
23.9
12.6
—
—
—
0
0
(3009261) Glucose [Presence] in Urine by Test strip
53
449
1.34
0.78
3.8
3.9
estimate
0.0
0.0
0.00
13
96
(3011288) Drugs identified in Urine by Screen method
5
23
2.23
0.77
3.8
1.6
—
—
—
0
0
(44816559) Phosphatidylethanol [Mass/volume] in Blood
5
23
2.23
0.77
1.2
1.3
—
—
—
0
0
(3016921) Smith extractable nuclear Ab [Units/volume] in Serum
5
23
2.23
0.77
1.2
1.4
—
3.6
—
0
5
(3006999) Ribonucleoprotein extractable nuclear Ab [Units/volume] in Serum
5
23
2.23
0.77
1.2
1.4
—
1.9
—
0
6
(3023602) Cholesterol in HDL [Moles/volume] in Serum or Plasma
95
883
1.48
0.75
5.8
4.2
mmol/l
1.4
1.5
1.19
86
817
(3021589) Normoblasts [#/volume] in Blood
50
422
1.33
0.74
11.7
9.9
e9/l
0.0
0.0
0.41
44
343
(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection
7
40
1.80
0.73
1.3
2.0
—
—
—
0
0
(3027273) Bicarbonate [Moles/volume] in Venous blood
7
42
1.71
0.70
3.4
2.9
mmol/l
26.7
24.9
—
7
42
(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection
20
147
1.44
0.67
1.8
1.9
—
—
—
0
0
(3020460) C reactive protein [Mass/volume] in Serum or Plasma
98
922
1.47
0.66
24.1
14.1
mg/l
28.5
21.5
1.30
92
709
(46235355) HIV 1 and 2 tests - Meaningful Use set
22
166
1.40
0.65
1.6
1.7
—
—
—
0
0
(3019900) Cholesterol [Moles/volume] in Serum or Plasma
95
890
1.42
0.64
5.6
4.2
mmol/l
4.5
4.7
0.97
86
828
(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum
10
63
1.64
0.64
1.2
1.2
—
41.6
—
0
6
(3006217) Methemoglobin/Hemoglobin.total in Arterial blood
8
50
1.64
0.63
10.1
8.8
%
0.5
0.8
—
8
50
(3003327) Ova and parasites identified in Stool by Light microscopy
5
30
1.70
0.62
2.6
1.7
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
12
81
1.54
0.60
1.3
1.1
—
—
—
0
0
(3027008) Opiates [Presence] in Urine
6
35
1.75
0.59
2.3
1.3
—
—
—
0
0
(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection
6
35
1.75
0.59
1.3
2.0
—
—
—
0
0
(3028300) Cannabinoids [Presence] in Urine
6
35
1.75
0.59
2.3
1.3
—
—
—
0
0
(3027944) Amphetamines [Presence] in Urine
6
35
1.75
0.59
2.3
1.2
—
—
—
0
0
(3000764) Benzodiazepines [Presence] in Urine
6
36
1.70
0.57
2.3
1.3
—
—
—
0
0
(3041096) Erythrocytes [Presence] in Urine by Automated
32
262
1.31
0.57
3.6
3.4
—
—
—
0
0
(3013707) Erythrocyte sedimentation rate by Westergren method
77
706
1.28
0.56
5.6
4.0
mm/h
17.9
10.6
2.64
71
645
(3018251) Fasting glucose [Moles/volume] in Serum or Plasma
93
876
1.35
0.53
5.8
4.3
mmol/l
6.4
5.9
2.02
82
802
(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection
13
92
1.47
0.53
1.8
1.7
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
13
92
1.47
0.53
3.8
3.8
—
—
—
0
0
(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture
23
182
1.33
0.52
1.7
1.6
—
—
—
0
0
(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma
21
165
1.33
0.49
1.6
1.2
iu/ml
19.7
28.4
—
6
58
(3016293) Bicarbonate [Moles/volume] in Serum or Plasma
7
46
1.56
0.49
6.7
5.5
mmol/l
24.2
25.5
—
7
46
(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood
7
50
1.43
0.46
9.7
8.9
%
0.9
1.5
—
7
50
(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood
11
78
1.45
0.45
13.9
4.0
mmol/l
1.2
1.2
0.87
11
66
(3042111) Morphology [Interpretation] in Bone marrow Narrative
0
16
0.00
0.41
0.0
2.5
—
—
—
0
0
(3025130) Human papilloma virus identified in Specimen
0
17
0.00
0.41
0.0
2.0
—
—
—
0
0
(3045414) Leukocytes [Presence] in Urine
5
34
1.49
0.41
3.0
1.6
—
—
—
0
0
(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum
6
41
1.49
0.36
1.0
1.1
—
—
—
0
0
(40768443) Skin Pathology biopsy report
6
45
1.35
0.34
1.2
1.2
—
—
—
0
0
(3025839) Triglyceride [Moles/volume] in Serum or Plasma
28
241
1.22
0.33
2.0
1.5
mmol/l
1.9
1.3
1.16
22
206
(3002256) Pathology report gross observation
15
121
1.28
0.30
1.2
1.3
—
—
—
0
0
(3019284) Hepatitis B virus surface Ag [Presence] in Serum
17
140
1.25
0.29
1.4
1.6
—
—
—
0
0
(3029937) Albumin [Presence] in Urine by Test strip
22
254
0.83
0.27
3.5
4.4
estimate
0.0
0.0
0.00
12
99
(40768804) Tissue Pathology biopsy report
42
382
1.16
0.27
2.7
2.0
—
—
—
0
0
(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma
94
908
1.21
0.26
6.2
4.6
mmol/l
2.5
2.7
1.95
84
835
(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum
19
161
1.22
0.26
1.4
1.2
u/ml
1.3
10.3
—
5
63
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
13
105
1.27
0.26
6.2
9.1
—
—
—
0
0
(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection
13
105
1.27
0.26
2.0
1.8
—
—
—
0
0
(1761868) Lipid panel - Serum or Plasma
31
346
0.86
0.26
4.1
2.7
—
—
—
0
0
(3022914) Cancer Ag 19-9 [Units/volume] in Serum or Plasma
5
41
1.23
0.22
4.4
3.3
u/ml
9.8
230.4
—
5
35
(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay
0
11
0.00
0.21
0.0
2.5
—
—
—
0
0
(3044941) Cell count panel - Synovial fluid
0
10
0.00
0.21
0.0
1.8
—
—
—
0
0
(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection
0
10
0.00
0.21
0.0
1.6
—
—
—
0
0
(3028167) CD3+CD4+ (T4 helper) cells [#/volume] in Blood
0
12
0.00
0.21
0.0
1.8
—
649.8
—
0
6
(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum
0
12
0.00
0.21
0.0
2.8
—
—
—
0
0
(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay
0
12
0.00
0.21
0.0
5.1
—
150.1
—
0
12
(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma
16
186
0.84
0.21
3.3
4.3
%
19.0
22.7
—
6
84
(3002385) Erythrocyte distribution width [Ratio]
75
781
0.88
0.21
26.5
16.5
%
14.0
13.7
1.12
75
767
(3003888) Timothy IgE Ab [Units/volume] in Serum
0
13
0.00
0.21
0.0
1.1
—
3.5
—
0
5
(3042631) Mycobacterium sp identified in Specimen
0
14
0.00
0.20
0.0
4.5
—
—
—
0
0
(3023351) European house dust mite IgE Ab [Units/volume] in Serum
0
14
0.00
0.20
0.0
1.2
—
0.6
—
0
7
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
58
612
0.89
0.20
3.5
3.1
—
—
—
0
0
(3019150) Specific gravity of Urine by Refractometry
21
187
1.15
0.17
3.7
4.7
kg/l
1.0
1.0
—
6
22
(40761536) Microorganisms panel - Urine sediment
11
92
1.22
0.16
3.7
3.6
—
—
—
0
0
(40760892) CBC W Ordered Manual Differential panel - Blood
20
222
0.88
0.15
5.6
5.5
—
—
—
0
0
(3017143) Hepatitis C virus Ab [Presence] in Serum
12
104
1.17
0.13
1.2
1.6
—
—
—
0
0
(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection
12
104
1.17
0.13
1.5
1.6
—
—
—
0
0
(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip
37
349
1.09
0.12
3.8
4.2
—
—
—
0
0
(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma
10
86
1.18
0.11
2.7
1.7
—
—
—
0
0
(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma
5
46
1.09
0.10
1.8
1.5
—
—
—
0
0
(3044491) Cholesterol non HDL [Mass/volume] in Serum or Plasma
5
62
0.80
0.08
1.4
1.5
—
—
—
0
0
(3019060) Gas panel - Arterial blood
7
65
1.08
0.08
7.0
3.2
—
—
—
0
0
(4010399)
7
65
1.08
0.08
1.6
1.4
—
—
—
0
0
(3021879) Hepatitis B virus core Ab [Presence] in Serum
7
66
1.06
0.08
1.1
1.6
—
—
—
0
0
(40761535) Cells panel - Urine sediment
7
80
0.87
0.07
3.3
4.1
—
—
—
0
0
(3000963) Hemoglobin [Mass/volume] in Blood
102
1009
1.11
0.06
35.1
20.8
g/l
129.9
135.0
2.63
102
993
(3000494) Fungus identified in Specimen by Culture
12
110
1.10
0.05
1.4
1.4
—
—
—
0
0
(40758558) Short blood count panel - Blood
25
259
0.96
0.03
7.5
7.0
—
—
—
0
0
(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep
14
148
0.94
0.02
1.0
1.4
—
—
—
0
0
(3044889) 12 lead EKG panel
61
618
0.97
0.02
4.0
3.8
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
14
142
0.98
0.00
3.0
2.9
ug/l
0.7
0.7
—
9
91
(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection
11
107
1.03
0.00
1.5
1.7
—
—
—
0
0
(3011397) Hemoglobin [Presence] in Urine by Test strip
20
203
0.98
0.00
3.4
4.0
—
—
—
0
0
(3013637) Mi-2 Ab [Presence] in Serum
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3015183) Erythrocyte sedimentation rate
0
8
0.00
0.00
0.0
1.5
—
—
—
0
0
(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.2
—
76.1
—
0
5
(3053028) Streptococcus sp identified in Specimen by Organism specific culture
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3035880) pH of Pleural fluid
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3045066) Thymidine kinase [Enzymatic activity/volume] in Serum
0
5
0.00
0.00
0.0
1.6
—
18.0
—
0
5
(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count
0
5
0.00
0.00
0.0
5.6
—
—
—
0
0
(42529598) SUMO-activating enzyme subunit 1 Ab [Presence] in Serum by Line blot
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(4198724)
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3008364) Apolipoprotein A-I [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
1.8
—
—
—
0
0
(42529582) MDA5 Ab [Presence] in Serum by Line blot
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(3000012) Reticulocyte production index
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0
(3045142) Bone marrow Pathology biopsy report
0
8
0.00
0.00
0.0
1.3
—
—
—
0
0
(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma
0
8
0.00
0.00
0.0
3.0
—
16.3
—
0
8
(42528593) TIF1-gamma Ab [Presence] in Serum by Line blot
0
5
0.00
0.00
0.0
1.0
—
—
—
0
0
(40768800) Prostate Pathology biopsy report
0
8
0.00
0.00
0.0
1.0
—
—
—
0
0
(3035637) Corticotropin [Mass/volume] in Plasma
0
9
0.00
0.00
0.0
1.9
—
—
—
0
0
(40757349) CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Blood
0
6
0.00
0.00
0.0
1.5
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
5
50
1.00
0.00
2.8
2.0
—
—
—
0
0
(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum
0
9
0.00
0.00
0.0
1.7
—
—
—
0
0
(3029080) Hemoglobin [Entitic mass] in Reticulocytes
0
9
0.00
0.00
0.0
3.4
—
33.1
—
0
9
(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
12.4
—
0.7
—
0
7
(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(1617658) Protocol used for examination of sentinel lymph nodes
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method
0
9
0.00
0.00
0.0
1.1
—
—
—
0
0
(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood
0
7
0.00
0.00
0.0
1.9
—
—
—
0
0
(21492711) Cytomegalovirus IgG Ab avidity [Presence] in Serum or Plasma by Immunoassay
0
7
0.00
0.00
0.0
1.3
—
—
—
0
0
(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid
0
6
0.00
0.00
0.0
1.2
—
—
—
0
0
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
8
89
0.89
0.00
2.8
1.5
—
—
—
0
0
(3022621) pH of Urine by Test strip
5
55
0.90
0.00
5.0
2.2
—
—
—
0
0
(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood
0
9
0.00
0.00
0.0
1.0
—
—
—
0
0
(3045716) Anion gap in Serum or Plasma
0
7
0.00
0.00
0.0
1.9
—
6.8
—
0
7
(3029075) Extractable nuclear Ab panel - Serum
0
6
0.00
0.00
0.0
1.0
—
—
—
0
0
(3000492) Spirometry study
8
85
0.94
0.00
1.8
1.5
—
—
—
0
0
(21494890) Protein electrophoresis panel - 24 hour Urine
0
6
0.00
0.00
0.0
6.2
—
—
—
0
0
(3035933) Granulocytes/100 leukocytes in Blood
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3028433) Virus identified in Specimen by Culture
0
6
0.00
0.00
0.0
1.7
—
—
—
0
0
(3021197) Magnesium Ionized [Moles/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
2.2
—
—
—
0
0
(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0
(21494434) Karyotype in Bone marrow
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection
0
6
0.00
0.00
0.0
1.8
—
—
—
0
0
(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum
0
9
0.00
0.00
0.0
1.3
—
—
—
0
0
(3014791) Apolipoprotein B [Mass/volume] in Serum or Plasma
0
6
0.00
0.00
0.0
2.0
—
0.9
—
0
6
Mortality – FinRegistry
↥Association
Association between endpoint E4_HYPERALI and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_HYPERALI | 2.001 [1.3, 3.08] | 0.002 |
| Birth year | 0.997 [0.99, 1.01] | 0.458 |
During the follow-up period (1.1.1998 — 31.12.2019), 64 out of 272 females with E4_HYPERALI died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| E4_HYPERALI | 3.536 [2.12, 5.89] | < 0.001 |
| Birth year | 0.988 [0.98, 1.0] | 0.011 |
During the follow-up period (1.1.1998 — 31.12.2019), 65 out of 172 males with E4_HYPERALI died.
Mortality risk
Mortality risk for people of age
years, who have E4_HYPERALI.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.189% | 0.859% |
| 5 | 1.144% | 4.315% |
| 10 | 3.079% | 10.302% |
| 15 | 5.724% | 18.891% |
| 20 | 9.954% | 29.966% |
Relationships between endpoints
↥Index endpoint: E4_HYPERALI – Other hyperalimentation
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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