Sequelae of hyperalimentation

E4_HYPERALISEQ

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — E68 Cause of death: ICD-10 — E68 2 out of 7 registries used, show all original rules.	63
4. Check minimum number of events None	63
5. Include endpoints None	63
6. Filter based on genotype QC (FinnGen only)	60

Control definitions (FinnGen only)

Control exclude: E4_OBESITY_HYPER

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: E65-E68
Name in latin: Sequelae hyperalimentationis

NAME	E4_HYPERALISEQ
CONTROL_EXCLUDE	E4_OBESITY_HYPER
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	E68
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	E68
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Sequelae of hyperalimentation based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	324	197	127
Only index persons	306	189	117
Unadjusted period prevalence (%)
Whole population	0.00	0.01	0.00
Only index persons	0.01	0.01	0.00
Median age at first event (years)
Whole population	-	49.24	58.24
Only index persons	52.05	48.89	57.17

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	60	41	19
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	52.40	48.89	59.98

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
63: Matched controls
630

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

E68

ICD-10 Finland

Sequelae of hyperalimentation

+∞

90.4

E66.8

ICD-10 Finland

Other obesity

459.8

29.3

E66.01

ICD-10 Finland

Obesity due to excess calories

41.6

25.6

E66.00

ICD-10 Finland

Metabolic syndrome

57.2

17.6

E66.9

ICD-10 Finland

Obesity, unspecified

105.0

15.4

QBJ30

NOMESCO Finland

Correction of abdominal apron

+∞

14.1

JDF11

NOMESCO Finland

Laparoscopic gastric bypass

+∞

11.8

SPAT1262

SPAT

Handing over of treatment supplies

7.2

11.2

T82

ICPC

Obesity

22.0

9.9

E11.9

ICD-10 Finland

Type 2 diabetes mellitus, without complications

5.1

8.9

E66.2

ICD-10 Finland

Extreme obesity with alveolar hypoventilation

+∞

8.5

Z71.3

ICD-10 Finland

Dietary counselling and surveillance

20.7

8.5

103

Kela drug reimbursment

Diabetes, insulin-treated

4.7

8.0

215

Kela drug reimbursment

Diabetes, non-insulin-treated

4.7

7.4

JL5BG

NOMESCO Finland

MRI examinaiton of bile and pancreas ducts with high intesity magnet

23.3

7.4

JKA21

NOMESCO Finland

Laparoscopic cholecystectomy

7.0

7.2

C03CA01

ATC

furosemide; systemic

3.9

6.5

113

310

Kela drug reimbursment

Orlistat, sibutramine and other major and expensive medicines used to treat obesity

+∞

6.3

E66

ICD-10 Finland

Obesity

14.5

6.3

T90

ICPC

Diabetes non-insulin dependent

4.2

6.2

R03BA05

ATC

fluticasone; inhalant

4.2

6.2

N02AX02

ATC

tramadol; systemic, rectal

3.8

6.2

189

UJD10

NOMESCO Finland

Esophagoscopy, gastroscopy and duodenoscopy

3.8

6.1

110

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3009508) Creatinine [Moles/volume] in Urine

117

4.53

8.11

4.6

2.8

6.77

7.94

mmol/l

0.61

103

(3019309) Folate [Moles/volume] in Red Blood Cells

4.76

8.10

2.1

1.6

1071.33

1208.52

nmol/l

0.32

(3020682) Albumin/Creatinine [Ratio] in Urine

119

4.43

7.89

5.6

3.4

8.14

7.05

mg/mmol

0.08

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

184

4.22

7.19

3.5

2.2

65.31

76.28

nmol/l

1.95

170

(3012516) Albumin [Mass/volume] in Urine

107

4.17

7.10

4.9

3.0

67.43

35.95

mg/l

0.30

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

175

3.95

6.69

2.7

1.8

103.21

96.06

pmol/l

0.32

(3004789) Transferrin [Mass/volume] in Serum or Plasma

4.11

5.81

2.6

2.2

2.61

2.39

g/l

0.92

(3022948) Iron [Moles/volume] in Serum or Plasma

3.94

5.64

2.8

2.2

10.71

13.50

umol/l

1.43

(3007853) Bacteria identified in Skin by Aerobe culture

3.79

4.26

5.9

1.5

—

(3022217) INR in Platelet poor plasma by Coagulation assay

218

2.87

4.01

9.0

12.7

1.18

1.13

inr

—

(3026493) Urate [Moles/volume] in Serum or Plasma

122

2.93

3.99

3.2

3.0

329.71

5376.01

umol/l

0.78

108

(3023368) Bacteria identified in Blood by Culture

122

2.93

3.99

4.7

4.5

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

4.53

3.73

1.7

1.5

—

(3019225) pH of Specimen

4.15

3.67

8.5

5.9

—

(3044640) Blood type and Crossmatch panel - Blood

159

2.69

3.59

3.0

2.2

—

(3042936) Bacteria identified in Isolate by Culture

3.16

3.57

2.9

1.7

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

7.70

3.46

1.9

1.4

—

(42529406) Shigella sp [Presence] in Stool by Culture

7.70

3.46

1.9

1.4

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

7.70

3.46

1.9

1.4

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

239

2.66

3.44

3.2

2.3

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

123

2.71

3.43

3.1

3.4

1347.93

1651.27

ng/l

0.15

106

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

9.30

3.33

1.5

1.3

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

218

2.52

3.18

9.3

6.7

1.21

1.22

mmol/l

0.43

185

(3025941) Bacteria identified in Stool by Culture

3.76

2.75

1.8

1.2

—

(3018010) Neutrophils/100 leukocytes in Blood

253

2.26

2.51

6.5

5.9

59.37

56.90

0.79

239

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

397

2.77

2.51

4.2

14.28

14.63

pmol/l

0.41

366

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

185

2.19

2.35

5.0

4.3

86.71

34.23

ng/l

0.51

113

(3002030) Lymphocytes/100 leukocytes in Blood

258

2.19

2.33

6.9

6.1

26.17

28.69

0.85

243

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

4.98

2.33

1.0

1.1

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

115

2.24

2.17

3.1

2.0

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

3.80

2.12

1.4

—

(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay

5.32

2.11

1.2

2.1

3.18

3.21

g/l

—

(3006504) Eosinophils/100 leukocytes in Blood

247

2.07

7.1

6.1

2.78

2.75

0.04

231

(3019069) Monocytes/100 leukocytes in Blood

249

2.04

2.00

7.5

6.4

7.51

8.42

1.34

233

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

4.83

1.98

1.2

1.0

—

(3020961) Endomysium IgA Ab [Titer] in Serum

3.29

1.86

1.0

1.1

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

488

2.76

1.82

5.1

3.6

1.56

1.26

mmol/l

1.28

459

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

489

2.74

1.82

19.8

12.9

83.06

83.94

ml/min/173m2

0.09

406

(3013512) EKG study

139

2.03

1.82

5.6

3.9

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

422

2.33

1.77

9.0

7.9

88.98

74.74

u/l

1.59

397

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

3.38

1.70

1.3

1.5

—

(3014007) Fractional oxyhemoglobin in Arterial blood

3.38

1.70

9.0

7.8

95.48

95.51

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

3.02

1.70

2.0

1.2

—

(3000991) Gas panel - Venous blood

2.90

1.63

9.0

11.0

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

2.90

1.63

3.6

2.5

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

2.90

1.63

1.4

1.3

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

3.05

1.54

8.7

7.2

0.45

0.78

—

(40768443) Skin Pathology biopsy report

2.68

1.50

1.1

—

(40768797) Stomach Pathology biopsy report

2.11

1.49

1.1

1.3

—

(3022313) Gas panel - Capillary blood

2.90

1.47

13.2

3.3

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

2.90

1.47

1.0

1.6

0.25

0.24

g/l

—

(3022096) Basophils/100 leukocytes in Blood

240

1.79

1.42

7.4

6.0

0.71

0.68

0.11

223

(3014576) Chloride [Moles/volume] in Serum or Plasma

2.33

1.40

9.7

6.8

103.56

104.52

mmol/l

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

2.19

1.24

3.6

3.8

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

2.77

1.24

7.6

7.9

—

(3022145) Colonoscopy Study observation

2.09

1.21

1.1

1.2

—

(3004588) Protein electrophoresis panel - Serum or Plasma

2.50

1.16

1.0

2.5

—

(3037467) Urinalysis macro (dipstick) panel - Urine

350

1.72

1.15

4.9

4.1

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

2.50

1.11

10.6

7.2

0.84

1.30

—

(3037522) Nuclear Ab [Titer] in Serum

1.94

1.09

1.5

176.00

465.60

titre

—

(3012544) pH of Venous blood

2.26

1.09

4.0

5.8

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

2.38

1.05

1.0

1.6

1.50

1.06

g/l

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

176

1.59

0.92

3.8

2.9

—

(3002582) Erythrocytes [#/volume] in Urine

158

1.60

0.91

3.0

13.73

407.32

e6/l

0.50

126

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

0.81

0.0

1.4

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

1.75

0.78

2.9

2.6

10.40

3.09

e6/l

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

128

1.57

0.77

1.3

1.2

0.76

0.69

u/ml

—

(3009445) Proteinase 3 Ab [Units/volume] in Serum

2.17

0.76

1.2

—

(3030467) Casts [#/volume] in Urine by Automated count

139

1.53

0.72

3.3

2.9

0.15

0.38

e6/l

0.62

107

(4035726) Immunohistochemistry procedure

1.75

0.71

1.0

1.2

—

(3003396) Base excess in Arterial blood by calculation

1.72

0.65

7.8

5.4

0.60

1.65

mmol/l

—

(3026008) Bacteria identified in Urine by Culture

151

1.48

0.65

2.2

2.4

—

(36304419) Bacteria [Presence] in Urine

142

1.48

0.64

3.3

2.8

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

509

1.63

0.62

6.1

4.0

6.70

5.77

mmol/l

2.89

472

(3018418) pH of Serum or Plasma

137

1.44

0.55

4.4

7.39

7.40

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.59

0.53

1.5

—

(40760892) CBC W Ordered Manual Differential panel - Blood

253

1.35

0.51

7.4

6.7

—

(1761868) Lipid panel - Serum or Plasma

213

0.72

0.47

4.1

2.5

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.49

0.45

1.6

1.7

—

(3001019) Free T4 and TSH panel - Serum or Plasma

1.66

0.44

1.2

2.1

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

1.61

0.43

1.8

1.5

—

(3002256) Pathology report gross observation

1.46

0.40

1.2

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

555

1.57

0.38

25.7

15.3

75.05

74.65

umol/l

0.03

555

(3018095) Leukocytes [#/volume] in Urine

184

1.30

0.37

3.8

3.4

13.87

37.60

e6/l

0.95

130

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.66

0.36

1.0

1.4

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

120

1.33

0.34

1.9

1.6

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.39

0.32

4.3

6.9

—

(40761536) Microorganisms panel - Urine sediment

1.39

0.32

3.9

3.7

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.38

0.30

1.8

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.29

0.29

1.8

1.7

—

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

143

1.26

0.27

2.0

1.5

1.84

1.32

mmol/l

0.53

126

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.21

0.0

1.1

—

(3025130) Human papilloma virus identified in Specimen

0.00

0.21

0.0

2.2

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.21

0.0

1.1

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.21

0.0

1.1

—

(3028626) Oxygen [Partial pressure] in Capillary blood

0.00

0.21

0.0

2.6

—

7.84

—

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.7

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.0

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.6

—

(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay

0.00

0.21

0.0

1.9

—

0.54

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.6

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.21

0.0

2.8

—

16.92

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

0.00

0.20

0.0

1.3

—

(3014051) Protein [Presence] in Urine by Test strip

0.00

0.20

0.0

1.5

—

(3044889) 12 lead EKG panel

355

1.18

0.20

4.1

3.5

—

(36660697) Celiac disease serology panel - Serum

1.17

0.19

1.3

1.2

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.17

0.19

3.2

1.6

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

1.26

0.19

2.7

1.8

—

(3000494) Fungus identified in Specimen by Culture

1.26

0.19

1.4

1.3

—

(3021601) Nitrite [Presence] in Urine by Test strip

256

1.17

0.19

5.0

5.1

0.00

estimate

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

101

1.23

0.18

1.5

1.8

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.13

0.17

1.9

1.8

—

(3003694) ABO and Rh group [Type] in Blood

141

1.18

0.16

1.7

1.4

—

(3009261) Glucose [Presence] in Urine by Test strip

259

1.15

0.15

3.5

3.7

0.00

estimate

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

199

0.87

0.14

3.7

3.9

—

(3035350) Ketones [Presence] in Urine by Test strip

256

1.10

0.08

3.3

3.7

0.00

estimate

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.13

0.06

1.5

1.6

—

(3002385) Erythrocyte distribution width [Ratio]

459

1.09

0.05

23.2

16.2

16.48

14.92

0.76

453

(40768804) Tissue Pathology biopsy report

220

1.07

0.04

2.4

2.0

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

111

1.10

0.04

2.7

3.3

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

360

0.94

0.04

4.1

3.1

—

(40758558) Short blood count panel - Blood

131

1.09

0.04

6.6

7.4

—

(3029937) Albumin [Presence] in Urine by Test strip

138

0.93

0.03

3.6

3.9

0.00

estimate

—

(3041096) Erythrocytes [Presence] in Urine by Automated

158

0.93

0.02

3.5

3.4

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.0

1.2

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.0

1.0

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

0.0

1.7

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

0.0

1.0

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.0

1.3

—

(3020629) Protein S Free Ag actual/normal in Platelet poor plasma by Immunoassay

0.00

0.0

1.0

—

93.17

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

0.0

1.0

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.0

2.5

—

2.25

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

0.0

1.2

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3028167) CD3+CD4+ (T4 helper) cells [#/volume] in Blood

0.00

0.0

1.3

—

638.83

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.3

—

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.8

—

(43055225) Phosphorylated tau 181 [Mass/volume] in Cerebral spinal fluid by Immunoassay

0.00

-0.00

0.0

1.0

—

47.00

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3029634) Reagin Ab [Titer] in Serum by VDRL

0.00

-0.00

0.0

2.2

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.1

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

-0.00

0.0

1.2

—

(3042810) Amyloid beta 42 peptide [Mass/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

393.60

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.6

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

0.00

-0.00

0.0

1.3

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

-0.00

0.0

2.9

—

105.57

—

(3042631) Mycobacterium sp identified in Specimen

0.00

-0.00

0.0

4.0

—

(3035637) Corticotropin [Mass/volume] in Plasma

0.00

-0.00

0.0

2.0

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

-0.00

0.0

1.0

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

-0.00

0.0

1.5

—

(3017569) Oxygen content in Arterial blood

0.00

-0.00

0.0

1.2

—

(3043849) Epstein Barr virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

1.7

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

-0.00

0.0

1.0

—

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

0.00

-0.00

0.0

1.0

—

(3001788) Aldosterone [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

184.20

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

0.95

-0.00

1.2

1.6

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

-0.00

0.0

1.1

—

91.60

—

(40768795) Lymph node Pathology biopsy report

0.00

-0.00

0.0

1.1

—

(46235689) Lupus anticoagulant aPTT, dRVVT and PT screening panel W Reflex

0.00

-0.00

0.0

1.7

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

-0.00

0.0

2.9

—

(3042111) Morphology [Interpretation] in Bone marrow Narrative

0.00

-0.00

0.0

3.8

—

(3045156) Carbon dioxide [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

3.4

—

(3020287) Protein C actual/normal in Platelet poor plasma by Coagulation assay

0.00

-0.00

0.0

1.0

—

118.43

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

5.9

—

140.63

—

(3024474) Albumin [Mass/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

252.00

—

(40768800) Prostate Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(40760888) Immunoglobulin light chains.free panel - Serum

0.00

-0.00

0.0

17.0

—

(3044941) Cell count panel - Synovial fluid

0.00

-0.00

0.0

1.3

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

-0.00

0.0

2.9

—

3.83

—

(3035933) Granulocytes/100 leukocytes in Blood

0.00

-0.00

0.0

1.0

—

(3022803) Oxygen [Partial pressure] adjusted to patient's actual temperature in Arterial blood

0.00

-0.00

0.0

3.4

—

(21494434) Karyotype in Bone marrow

0.00

-0.00

0.0

1.0

—

(3021197) Magnesium Ionized [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.4

—

(36032269) Testosterone Free [Moles/volume] in Serum or Plasma by calculation

0.00

-0.00

0.0

1.9

—

230.13

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

2.0

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

23.93

—

(3021901) Oxygen saturation in Capillary blood

0.00

-0.00

0.0

2.9

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

-0.00

0.0

4.0

—

34.00

—

(3000242) Tau protein [Mass/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.0

—

313.40

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3006442) Creatine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.8

—

73.60

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

-0.00

0.0

2.2

—

(3011985) Renin [Units/volume] in Plasma

0.00

-0.00

0.0

1.4

—

11.26

—

Mortality – FinRegistry

↥

Association

Association between endpoint E4_HYPERALISEQ and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have E4_HYPERALISEQ.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: E4_HYPERALISEQ – Sequelae of hyperalimentation

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Sequelae of hyperalimentation

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints