Sequelae of hyperalimentation

E4_HYPERALISEQ

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — E68 Cause of death: ICD-10 — E68 2 out of 7 registries used, show all original rules.	59
4. Check minimum number of events None	59
5. Include endpoints None	59
6. Filter based on genotype QC (FinnGen only)	59

Control definitions (FinnGen only)

Control exclude: E4_OBESITY_HYPER

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: E65-E68
Name in latin: Sequelae hyperalimentationis

NAME	E4_HYPERALISEQ
CONTROL_EXCLUDE	E4_OBESITY_HYPER
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	E68
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	E68
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Sequelae of hyperalimentation based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	324	197	127
Only index persons	306	189	117
Unadjusted period prevalence (%)
Whole population	0.00	0.01	0.00
Only index persons	0.01	0.01	0.00
Median age at first event (years)
Whole population	-	49.24	58.24
Only index persons	52.05	48.89	57.17

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	59	39	20
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	51.35	48.06	57.77

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
58: Matched controls
578

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

E68

ICD-10 Finland

Sequelae of hyperalimentation

+∞

83.1

E66.01

ICD-10 Finland

Obesity due to excess calories

174.8

28.7

E66.8

ICD-10 Finland

Other obesity

+∞

27.2

E66.9

ICD-10 Finland

Obesity, unspecified

+∞

17.6

E66.00

ICD-10 Finland

Metabolic syndrome

78.3

15.8

QBJ30

NOMESCO Finland

Correction of abdominal apron

+∞

14.1

JDF11

NOMESCO Finland

Laparoscopic gastric bypass

+∞

8.5

E66.2

ICD-10 Finland

Extreme obesity with alveolar hypoventilation

+∞

8.5

E11.9

ICD-10 Finland

Type 2 diabetes mellitus, without complications

6.3

8.3

T82

ICPC

Obesity

14.7

6.9

Z71.3

ICD-10 Finland

Dietary counselling and surveillance

16.9

6.7

103

Kela drug reimbursment

Diabetes, insulin-treated

4.6

6.3

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3019309) Folate [Moles/volume] in Red Blood Cells

4.83

7.81

2.1

1.6

1061.7

1205.4

nmol/l

0.32

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

174

4.33

6.95

3.6

2.3

65.2

76.9

nmol/l

1.96

160

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

170

4.16

6.65

2.8

1.8

105.6

96.0

pmol/l

0.46

(3009508) Creatinine [Moles/volume] in Urine

114

4.04

6.48

4.9

2.8

6.8

8.0

mmol/l

0.60

(3020682) Albumin/Creatinine [Ratio] in Urine

116

3.95

6.29

6.0

3.5

8.6

7.0

mg/mmol

0.12

(3004789) Transferrin [Mass/volume] in Serum or Plasma

4.20

5.64

2.6

2.3

2.6

2.4

g/l

0.93

(3012516) Albumin [Mass/volume] in Urine

104

3.68

5.52

5.3

3.0

71.3

36.0

mg/l

0.33

(3022948) Iron [Moles/volume] in Serum or Plasma

4.00

5.47

2.8

2.2

10.7

13.7

umol/l

1.49

(3007853) Bacteria identified in Skin by Aerobe culture

4.34

5.00

5.9

1.5

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

4.60

4.51

1.7

1.5

—

(3019225) pH of Specimen

4.35

4.49

8.5

6.0

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

229

3.07

4.05

5.8

4.0

—

(3044640) Blood type and Crossmatch panel - Blood

155

2.90

3.90

3.0

2.2

—

(3032080) INR in Blood by Coagulation assay

182

2.85

3.77

5.1

7.1

1.2

1.1

inr

—

(3042936) Bacteria identified in Isolate by Culture

3.27

3.70

2.9

1.7

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

267

2.99

3.61

5.0

4.4

7.1

6.5

mmol/l

0.84

243

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

7.76

3.47

1.9

1.4

—

(42529406) Shigella sp [Presence] in Stool by Culture

7.76

3.47

1.9

1.4

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

7.76

3.47

1.9

1.4

—

(3026493) Urate [Moles/volume] in Serum or Plasma

116

2.80

3.46

3.1

332.9

5783.2

umol/l

0.78

100

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

118

2.74

3.33

2.6

3.4

1412.0

1697.5

ng/l

0.13

103

(3023368) Bacteria identified in Blood by Culture

119

2.71

3.27

4.8

4.5

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

211

2.62

3.20

9.5

6.8

1.2

mmol/l

0.44

178

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

8.18

3.13

1.5

1.4

—

(3025941) Bacteria identified in Stool by Culture

3.89

2.61

1.9

1.2

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

364

2.71

2.36

4.1

4.3

14.3

14.7

pmol/l

0.48

336

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

113

2.33

2.30

3.1

2.0

—

(3018010) Neutrophils/100 leukocytes in Blood

235

2.20

2.23

6.8

6.0

59.0

57.1

0.50

221

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

3.82

2.13

1.4

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

3.82

2.13

2.0

1.3

—

(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay

5.34

2.11

1.2

2.1

3.2

g/l

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

455

3.20

2.11

5.2

3.7

1.6

1.3

mmol/l

1.05

427

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

4.85

1.98

1.2

1.0

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

179

2.07

1.96

4.9

4.4

94.3

34.2

ng/l

0.54

113

(3013139) Helicobacter pylori Ag [Presence] in Stool

3.31

1.86

1.4

1.3

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

4.44

1.86

1.0

1.1

—

(40768797) Stomach Pathology biopsy report

2.35

1.83

1.1

1.3

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

3.59

1.79

1.0

1.4

0.3

0.2

g/l

—

(3020961) Endomysium IgA Ab [Titer] in Serum

3.59

1.79

1.0

1.1

—

(3006504) Eosinophils/100 leukocytes in Blood

230

1.99

1.77

7.4

6.2

2.8

2.7

0.10

214

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

397

2.38

1.72

9.0

8.0

89.9

75.1

u/l

1.56

375

(3019069) Monocytes/100 leukocytes in Blood

232

1.96

1.71

7.9

6.5

7.6

8.6

1.26

216

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

3.03

1.71

3.6

2.4

—

(3014007) Fractional oxyhemoglobin in Arterial blood

3.39

1.71

9.0

7.8

95.5

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

454

2.64

1.68

20.4

13.4

82.9

ml/min/173m2

0.00

377

(3000991) Gas panel - Venous blood

2.91

1.64

9.0

11.0

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

3.22

1.62

8.7

7.5

0.5

0.8

—

(3022313) Gas panel - Capillary blood

3.22

1.62

13.2

3.5

—

(3017895) Helicobacter pylori Ab [Units/volume] in Serum

3.31

1.47

1.2

1.4

—

(3037467) Urinalysis macro (dipstick) panel - Urine

325

1.86

1.33

5.0

4.2

—

(3013512) EKG study

136

1.84

1.33

5.7

4.0

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

2.94

1.31

1.0

1.4

1.5

1.0

g/l

—

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

2.78

1.24

7.6

7.9

—

(40768443) Skin Pathology biopsy report

2.45

1.22

1.2

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

2.63

1.17

10.6

7.5

0.8

1.3

—

(3012544) pH of Venous blood

2.34

1.12

4.0

6.0

—

(3022096) Basophils/100 leukocytes in Blood

225

1.68

1.11

7.8

6.1

0.7

0.10

208

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

165

1.65

0.99

3.9

3.0

—

(3004588) Protein electrophoresis panel - Serum or Plasma

2.19

0.92

1.0

2.6

—

(3002582) Erythrocytes [#/volume] in Urine

152

1.59

0.85

3.0

13.9

431.0

e6/l

0.50

119

(42870588) Differential panel, method unspecified - Blood

162

1.57

0.83

7.2

5.6

—

(3003396) Base excess in Arterial blood by calculation

1.77

0.82

7.8

5.5

0.6

1.6

mmol/l

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

1.79

0.82

2.9

2.6

10.4

2.9

e6/l

—

(3022145) Colonoscopy Study observation

1.78

0.79

1.1

1.2

—

(3009445) Proteinase 3 Ab [Units/volume] in Serum

2.28

0.78

1.2

—

(1761868) Lipid panel - Serum or Plasma

196

0.63

0.74

4.2

2.6

—

(4035726)

1.85

0.74

1.0

1.2

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

1.86

0.68

1.8

1.5

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.69

0.65

4.1

3.8

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.66

0.64

1.6

1.7

—

(3030467) Casts [#/volume] in Urine by Automated count

134

1.49

0.63

3.3

3.0

0.2

0.4

e6/l

0.59

101

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

0.61

0.0

1.4

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.56

0.57

1.3

1.4

—

(36304419) Bacteria [Presence] in Urine

137

1.45

0.56

3.3

2.9

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

474

1.56

0.52

6.1

4.0

6.7

5.8

mmol/l

2.56

439

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.49

0.48

4.3

7.2

—

(3009542) Hematocrit [Volume Fraction] of Blood

452

1.50

0.47

24.3

13.0

38.9

40.2

0.53

351

(3000494) Fungus identified in Specimen by Culture

1.45

0.47

1.4

1.3

—

(3002256) Pathology report gross observation

1.49

0.42

1.2

—

(40760892) CBC W Ordered Manual Differential panel - Blood

121

0.70

0.40

5.3

5.8

—

(3026008) Bacteria identified in Urine by Culture

136

1.35

0.39

2.3

2.4

—

(3018095) Leukocytes [#/volume] in Urine

175

1.31

0.37

3.9

3.4

14.7

39.8

e6/l

0.94

122

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.42

0.33

1.9

1.7

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

1.39

0.33

2.7

1.8

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.40

0.33

1.8

1.7

—

(3015736) pH of Urine

178

1.28

0.32

3.1

3.5

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.35

0.31

1.5

1.7

—

(3003694) ABO and Rh group [Type] in Blood

132

1.29

0.30

1.7

1.4

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

520

1.45

0.28

26.5

15.8

75.6

75.3

umol/l

0.02

520

(3002385) Erythrocyte distribution width [Ratio]

418

0.80

0.27

26.6

16.7

14.3

13.5

2.62

411

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

106

1.29

0.26

2.0

1.5

—

(3021601) Nitrite [Presence] in Urine by Test strip

234

1.20

0.22

4.7

5.2

0.0

estimate

—

(3030905) Polymorphonuclear cells [#/volume] in Blood

0.00

0.21

0.0

2.5

—

5.8

—

(3014051) Protein [Presence] in Urine by Test strip

0.00

0.21

0.0

1.6

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

0.21

0.0

1.1

—

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.7

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

0.21

0.0

1.1

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.6

—

(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay

0.00

0.21

0.0

1.9

—

0.5

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.6

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

0.00

0.21

0.0

4.1

—

62.0

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

0.00

0.21

0.0

1.3

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.21

0.0

2.8

—

16.9

—

(36660697) Celiac disease serology panel - Serum

1.25

0.21

1.3

1.2

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.17

0.20

3.2

1.6

—

(3009261) Glucose [Presence] in Urine by Test strip

236

1.18

0.19

3.3

3.8

0.0

estimate

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.21

0.19

2.0

1.8

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

102

1.22

0.17

2.7

3.4

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.74

0.17

1.0

1.4

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.23

0.15

1.5

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

178

0.86

0.13

3.4

4.1

—

(3035350) Ketones [Presence] in Urine by Test strip

232

1.13

0.12

3.0

3.8

0.0

estimate

—

(40768804) Tissue Pathology biopsy report

203

1.13

0.12

2.5

2.0

—

(3044889) 12 lead EKG panel

333

1.13

0.11

4.0

3.6

—

(3029937) Albumin [Presence] in Urine by Test strip

124

0.86

0.10

3.6

4.0

0.0

estimate

—

(3041096) Erythrocytes [Presence] in Urine by Automated

144

0.88

0.09

3.2

3.5

—

(40761536) Microorganisms panel - Urine sediment

1.05

0.09

4.2

3.8

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

330

0.93

0.04

4.3

3.1

—

(40758558) Short blood count panel - Blood

125

1.05

0.00

7.1

—

(3021197) Magnesium Ionized [Moles/volume] in Serum or Plasma

0.00

0.0

2.4

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

0.0

3.0

—

(3029634) Reagin Ab [Titer] in Serum by VDRL

0.00

0.0

2.2

—

(42529215) Follitropin [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

1.8

—

59.0

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

0.0

1.0

—

(3044941) Cell count panel - Synovial fluid

0.00

0.0

1.3

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

0.0

2.2

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(40768800) Prostate Pathology biopsy report

0.00

0.0

1.0

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.0

1.4

—

(3021901) Oxygen saturation in Capillary blood

0.00

0.0

3.0

—

(3020287) Protein C actual/normal in Platelet poor plasma by Coagulation assay

0.00

0.0

1.0

—

118.4

—

(40768795) Lymph node Pathology biopsy report

0.00

0.0

1.1

—

(3011166) Borrelia burgdorferi Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

0.00

0.0

1.0

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

0.0

1.0

—

(3024474) Albumin [Mass/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

252.0

—

(4268621)

0.00

0.0

1.7

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.00

0.00

1.2

1.6

—

(40760888) Immunoglobulin light chains.free panel - Serum

0.00

0.0

17.0

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

0.0

1.7

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

0.0

3.0

—

105.3

—

(3035637) Corticotropin [Mass/volume] in Plasma

0.00

0.0

2.0

—

(4306422)

0.00

0.0

1.0

—

(3020629) Protein S Free Ag actual/normal in Platelet poor plasma by Immunoassay

0.00

0.0

1.0

—

93.2

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

0.0

3.0

—

3.9

—

(3042631) Mycobacterium sp identified in Specimen

0.00

0.0

4.0

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

0.00

0.0

1.3

—

(3043849) Epstein Barr virus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

0.00

0.0

1.7

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

0.0

1.1

—

91.6

—

(3017569) Oxygen content in Arterial blood

0.00

0.0

1.2

—

(3028626) Oxygen [Partial pressure] in Capillary blood

0.00

0.0

2.7

—

7.7

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.0

6.4

—

159.4

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

0.0

1.0

—

(40766800) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ T-cells [Units/volume] corrected for background in Blood

0.00

0.0

1.0

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

0.0

2.0

—

(36033641) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Rapid immunoassay

0.00

0.0

1.2

—

(36032269) Testosterone Free [Moles/volume] in Serum or Plasma by calculation

0.00

0.0

1.9

—

230.1

—

(3025130) Human papilloma virus identified in Specimen

0.00

0.0

2.3

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

0.0

1.6

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.1

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.0

1.1

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

0.0

2.5

—

2.3

—

(3009595) Pneumocystis jiroveci DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.8

—

(3042111) Morphology [Interpretation] in Bone marrow Narrative

0.00

0.0

3.8

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

0.0

4.0

—

34.0

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(21494434) Karyotype in Bone marrow

0.00

0.0

1.0

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.3

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

24.6

—

Mortality – FinRegistry

↥

Association

Association between endpoint E4_HYPERALISEQ and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have E4_HYPERALISEQ.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: E4_HYPERALISEQ – Sequelae of hyperalimentation

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Sequelae of hyperalimentation

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints