This is a non-core endpoint: only basic statistics are computed.

Dietary calcium deficiency

E4_CA_DEF

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — E58 Cause of death: ICD-10 — E58 2 out of 7 registries used, show all original rules.	12
4. Check minimum number of events None	12
5. Include endpoints None	12
6. Filter based on genotype QC (FinnGen only)	12

Control definitions (FinnGen only)

Control exclude: E4_NUTRIDEF

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: E50-E64
Name in latin: Deficientia calcii diaetaria

NAME	E4_CA_DEF
CONTROL_EXCLUDE	E4_NUTRIDEF
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	E58
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	E58
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Dietary calcium deficiency based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	95	58	37
Only index persons	81	49	32
Unadjusted period prevalence (%)
Whole population	0.00	0.00	0.00
Only index persons	0.00	0.00	0.00
Median age at first event (years)
Whole population	-	50.77	54.44
Only index persons	51.17	50.31	52.48

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	12	7	5
Unadjusted period prevalence (%)	0.00	0.00	0.00
Median age at first event (years)	49.47	43.07	58.44

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

(ID) Name

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(42870588) Differential panel, method unspecified - Blood

2.84

1.02

5.0

4.1

—

(40768804) Tissue Pathology biopsy report

2.23

0.69

2.2

1.8

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

0.45

0.65

7.2

5.0

15.3

15.0

pmol/l

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

0.45

0.53

7.7

5.2

1.4

1.9

mu/l

—

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

0.00

0.44

0.0

1.7

—

3.9

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

1.73

0.29

3.6

1.9

103.8

79.6

nmol/l

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

1.73

0.29

3.4

1.7

139.8

145.8

ug/l

—

(3026008) Bacteria identified in Urine by Culture

1.48

0.27

2.4

2.5

—

(3013707) Erythrocyte sedimentation rate by Westergren method

0.60

0.27

7.5

3.1

7.0

13.7

mm/h

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.00

0.22

0.0

1.5

—

(3042936) Bacteria identified in Isolate by Culture

0.00

0.22

0.0

2.5

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

1.32

0.12

2.6

3.4

—

(3009261) Glucose [Presence] in Urine by Test strip

1.30

0.12

2.7

3.4

—

0.0

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

0.72

0.12

2.8

2.4

—

(21494755) Public health laboratory ask at order entry panel

0.00

0.0

1.2

—

(3049717) Cytology report of Urine Cyto stain

0.00

0.0

3.4

—

(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

3.4

—

0.0

—

(4035726)

0.00

0.0

1.1

—

(3007930) Methemoglobin/Hemoglobin.total in Blood

0.00

0.0

3.7

—

0.8

—

(3037551) Cancer Ag 125 [Units/volume] in Serum or Plasma

0.00

0.0

2.2

—

33.6

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

2.7

—

0.0

—

(3025159) Blasts/100 leukocytes in Blood

0.00

0.0

1.8

—

(3004588) Protein electrophoresis panel - Serum or Plasma

0.00

0.0

2.3

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

0.00

0.0

1.0

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

0.00

0.0

1.3

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

0.00

0.0

1.2

—

(3021440) Promyelocytes/100 leukocytes in Blood

0.00

0.0

1.9

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

3.4

—

0.0

—

(4010399)

0.00

0.0

1.3

—

(3005895) Myoglobin [Mass/volume] in Serum or Plasma

0.00

0.0

2.5

—

1082.2

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

0.00

0.0

2.8

—

24.2

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

0.00

0.0

2.2

—

82.0

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

0.00

0.0

4.1

—

1.5

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

0.00

0.0

2.0

—

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

0.00

0.0

3.1

—

7.4

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

0.00

0.0

1.2

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

0.00

0.0

2.6

—

55.6

—

(3020891) Body temperature

0.00

0.0

2.3

—

(3019225) pH of Specimen

0.00

0.0

3.3

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

1.11

0.00

2.8

2.7

—

(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

2.7

—

1.0

—

(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

2.7

—

10.7

—

(3015322) Alpha 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

2.7

—

2.8

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

0.0

4.0

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

1.14

0.00

1.8

2.6

—

(3002179) Metamyelocytes/100 leukocytes in Blood

0.00

0.0

1.9

—

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

2.7

—

(3005229) Alpha 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.0

2.7

—

7.7

—

(3017181) Myelocytes/100 leukocytes in Blood

0.00

0.0

1.8

—

Mortality – FinRegistry

↥

Association

Association between endpoint E4_CA_DEF and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have E4_CA_DEF.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: E4_CA_DEF – Dietary calcium deficiency

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Dietary calcium deficiency

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints