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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Typhus fever

AB1_TYPHUS_FEVER

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

520210

1. Apply sex-specific rule

None

520210

2. Check conditions

None

520210

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 A75
  • Hospital discharge: ICD-9 08[0-1]
  • Hospital discharge: ICD-8 08[0]
  • Cause of death: ICD-10 A75
  • Cause of death: ICD-9 08[0-1]
  • Cause of death: ICD-8 08[0]

2 out of 7 registries used, show all original rules.

12

4. Check minimum number of events

None

12

5. Include endpoints

None

12

6. Filter based on genotype QC (FinnGen only)

12

Control definitions (FinnGen only)

Control exclude
AB1_RICKETTSIOSES

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF5

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Not enough data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 163 71 90
Only index persons 141 62 79
Unadjusted period prevalence (%)
Whole population 0.00 0.00 0.00
Only index persons 0.00 0.00 0.00
Median age at first event (years)
Whole population 46.73 48.17 45.89
Only index persons 44.91 46.12 43.97

-FinnGen-

Key figures

All Female Male
Number of individuals 12 8 -
Unadjusted period prevalence (%) 0.00 0.00 -
Median age at first event (years) 45.98 46.29 -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
unit
cases
controls
-log10(p)
N cases
N controls
(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma
7
33
3.65
1.36
7.4
2.7
mmol/l
1.2
1.2
—
7
25
(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma
6
30
2.97
1.06
1.7
2.0
u/l
48.2
51.3
—
6
30
(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma
6
33
2.61
0.74
4.3
2.9
mmol/l
1.2
1.2
—
6
27
(3001079) Blood group antibody screen [Presence] in Serum or Plasma
5
31
2.04
0.51
2.6
3.2
—
—
—
0
0
(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma
0
14
0.00
0.44
0.0
3.0
—
0.7
—
0
6
(43054914) Glucose tolerance 2 hours panel - Serum or Plasma
0
17
0.00
0.44
0.0
1.7
—
—
—
0
0
(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)
7
85
0.58
0.29
10.7
11.1
ml/min/173m2
93.0
86.0
—
7
69
(3003338) MCHC [Mass/volume]
7
81
0.68
0.27
19.9
13.9
g/l
324.7
331.4
—
7
81
(3022621) pH of Urine by Test strip
0
10
0.00
0.22
0.0
2.8
—
—
—
0
0
(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection
7
62
1.31
0.12
5.4
3.2
—
—
—
0
0
(3044889) 12 lead EKG panel
6
62
0.94
0.00
3.3
3.3
—
—
—
0
0
(3017446) Testosterone [Moles/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
3.0
—
17.5
—
0
5
(3025941) Bacteria identified in Stool by Culture
0
8
0.00
0.00
0.0
1.1
—
—
—
0
0
(40761535) Cells panel - Urine sediment
0
5
0.00
0.00
0.0
2.8
—
—
—
0
0
(36660697) Celiac disease serology panel - Serum
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal
0
7
0.00
0.00
0.0
1.0
—
—
—
0
0
(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma
7
67
1.11
0.00
4.3
4.1
pmol/l
15.2
14.7
—
7
62
(3013707) Erythrocyte sedimentation rate by Westergren method
7
66
1.14
0.00
6.6
3.6
mm/h
9.7
9.6
—
7
61
(3012336) Haptoglobin [Mass/volume] in Serum or Plasma
0
5
0.00
0.00
0.0
2.0
—
0.9
—
0
5
(3013742) Prealbumin [Mass/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
3.6
—
0.2
—
0
7
(44816559) Phosphatidylethanol [Mass/volume] in Blood
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3000492) Spirometry study
0
6
0.00
0.00
0.0
1.3
—
—
—
0
0
(3000330) Specific gravity of Urine by Test strip
0
5
0.00
0.00
0.0
1.6
—
—
—
0
0
(3042936) Bacteria identified in Isolate by Culture
0
9
0.00
0.00
0.0
2.1
—
—
—
0
0
(3025130) Human papilloma virus identified in Specimen
0
5
0.00
0.00
0.0
1.2
—
—
—
0
0
(3001019) Free T4 and TSH panel - Serum or Plasma
0
9
0.00
0.00
0.0
2.2
—
—
—
0
0
(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma
0
9
0.00
0.00
0.0
5.1
—
—
—
0
0
(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma
7
70
1.00
0.00
6.1
6.6
u/l
80.3
72.1
—
7
63
(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay
0
6
0.00
0.00
0.0
2.5
—
—
—
0
0
(40761536) Microorganisms panel - Urine sediment
0
9
0.00
0.00
0.0
2.7
—
—
—
0
0
(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture
0
8
0.00
0.00
0.0
3.0
—
—
—
0
0
(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3027238) Thyroperoxidase Ab [Units/volume] in Serum or Plasma
0
7
0.00
0.00
0.0
1.1
—
—
—
0
0
(3004716) Salmonella sp identified in Stool by Organism specific culture
0
7
0.00
0.00
0.0
1.7
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint AB1_TYPHUS_FEVER and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have AB1_TYPHUS_FEVER.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: AB1_TYPHUS_FEVER – Typhus fever

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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