Disorders of olfactory nerve

G6_DISOLF

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	519972
1. Apply sex-specific rule None	519972
2. Check conditions None	519972
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — G52.0 Hospital discharge: ICD-9 — 3520 Hospital discharge: ICD-8 — 35600 Cause of death: ICD-10 — G52.0 Cause of death: ICD-9 — 3520 Cause of death: ICD-8 — 35600 2 out of 7 registries used, show all original rules.	39
4. Check minimum number of events None	39
5. Include endpoints None	39
6. Filter based on genotype QC (FinnGen only)	38

Control definitions (FinnGen only)

Control exclude: G6_NERPLEX

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: G52
Name in latin: Morbositates nervi olfactorii

NAME	G6_DISOLF
CONTROL_EXCLUDE	G6_NERPLEX
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	G520
HD_ICD_9	3520
HD_ICD_8	35600
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	G520
COD_ICD_9	3520
COD_ICD_8	35600
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Disorders of olfactory nerve based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	260	154	103
Only index persons	228	133	95
Unadjusted period prevalence (%)
Whole population	0.00	0.00	0.00
Only index persons	0.00	0.00	0.00
Median age at first event (years)
Whole population	54.60	56.07	52.41
Only index persons	53.84	54.68	52.66

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	38	25	13
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	55.42	53.68	58.76

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

111

2.93

2.70

1.8

2.0

98.03

92.51

pmol/l

0.28

(40768797) Stomach Pathology biopsy report

2.85

1.61

1.2

—

(3013512) EKG study

2.24

1.50

4.1

4.0

—

(3014111) Lactate [Moles/volume] in Serum or Plasma

2.71

1.19

3.0

7.5

1.00

1.13

mmol/l

—

(3022145) Colonoscopy Study observation

2.53

1.17

1.4

—

(3013707) Erythrocyte sedimentation rate by Westergren method

229

2.04

1.08

3.6

4.1

7.65

10.71

mm/h

1.03

204

(3015736) pH of Urine

125

1.82

0.96

2.3

2.9

—

5.94

—

(3037467) Urinalysis macro (dipstick) panel - Urine

206

1.79

0.86

3.5

4.2

—

(3042936) Bacteria identified in Isolate by Culture

1.96

0.78

2.0

1.4

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

2.24

0.77

1.4

2.0

—

(3019225) pH of Specimen

2.24

0.77

2.2

4.1

—

(3000492) Spirometry study

2.14

0.76

1.4

—

(3033658) Prothrombin time (PT) actual/Normal

1.82

0.73

4.1

3.5

86.60

94.63

—

(40761535) Cells panel - Urine sediment

1.97

0.71

2.4

3.6

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

125

1.64

0.70

2.6

3.5

—

(40768804) Tissue Pathology biopsy report

126

1.62

0.67

2.6

2.1

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.83

0.66

2.2

1.4

—

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

246

1.70

0.66

8.5

6.4

100.17

78.22

u/l

0.85

224

(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma

1.76

0.63

5.2

3.4

35.22

158.25

ug/l

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

291

1.87

0.62

5.2

4.9

39.00

38.96

mmol/mol

0.01

271

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

1.59

0.55

3.3

3.1

—

(3023368) Bacteria identified in Blood by Culture

1.60

0.50

6.2

4.2

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

296

1.74

0.50

4.2

4.7

1.65

2.00

mu/l

1.18

260

(3007853) Bacteria identified in Skin by Aerobe culture

1.70

0.45

2.6

1.7

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

1.47

0.43

2.8

3.3

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

0.00

0.42

0.0

1.5

—

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.00

0.41

0.0

1.5

—

(3002256) Pathology report gross observation

1.50

0.38

1.8

1.1

—

(3026008) Bacteria identified in Urine by Culture

1.44

0.37

2.7

2.8

—

(3000494) Fungus identified in Specimen by Culture

1.47

0.37

1.7

1.4

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.43

0.36

6.5

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

296

1.45

0.36

13.8

11.2

85.38

81.10

ml/min/173m2

0.50

238

(40760892) CBC W Ordered Manual Differential panel - Blood

139

0.71

0.35

4.3

6.0

—

(3008486) Thyroxine (T4) free [Moles/volume] in Serum or Plasma

242

1.38

0.32

3.7

4.0

14.34

14.70

pmol/l

0.41

210

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

144

1.32

0.29

2.5

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

204

0.78

0.24

3.2

3.1

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

0.00

0.22

0.0

1.2

—

1.30

—

(3020891) Body temperature

0.00

0.21

0.0

4.8

—

(3008898) HLA-B27 [Presence]

0.00

0.21

0.0

1.3

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.20

0.0

1.4

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.72

0.18

1.2

1.3

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

1.16

0.17

2.9

2.1

—

(40758558) Short blood count panel - Blood

0.73

0.17

9.0

5.9

—

(3041096) Erythrocytes [Presence] in Urine by Automated

1.25

0.17

2.4

3.0

—

(3048689) Calprotectin [Mass/mass] in Stool

1.13

0.10

1.4

1.6

81.60

175.28

ug/g

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.07

0.10

1.8

2.0

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.08

0.09

3.3

2.1

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.05

0.08

1.7

1.5

—

(36304419) Bacteria [Presence] in Urine

0.83

0.08

5.0

2.8

—

(3022096) Basophils/100 leukocytes in Blood

132

0.87

0.08

4.3

5.8

0.63

0.61

0.06

123

(3002030) Lymphocytes/100 leukocytes in Blood

141

0.88

0.06

4.2

5.7

24.52

28.46

0.62

132

(3003694) ABO and Rh group [Type] in Blood

1.13

0.05

1.3

1.5

—

(3018095) Leukocytes [#/volume] in Urine

1.13

0.05

3.9

3.2

640.48

26.52

e6/l

—

(3019069) Monocytes/100 leukocytes in Blood

137

0.92

0.02

4.4

6.0

7.44

8.48

0.66

128

(3006504) Eosinophils/100 leukocytes in Blood

136

0.93

0.01

4.1

5.8

2.56

2.73

0.15

127

(3018010) Neutrophils/100 leukocytes in Blood

136

0.93

0.01

4.1

5.5

62.07

57.49

0.71

127

(1761868) Lipid panel - Serum or Plasma

1.07

0.00

3.0

2.3

—

(3044640) Blood type and Crossmatch panel - Blood

1.07

0.00

3.0

2.1

—

(3044889) 12 lead EKG panel

221

0.99

0.00

4.6

3.4

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.0

1.7

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

0.00

0.0

2.2

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

0.00

0.0

1.0

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

0.0

1.2

—

(3021387) Prolactin [Units/volume] in Serum or Plasma

0.00

0.0

2.3

—

414.22

—

(4034850) Laboratory test

0.00

0.0

8.8

—

(3007844) Epstein Barr virus capsid IgM Ab [Units/volume] in Serum by Immunoassay

0.00

0.0

1.7

—

(3005033) Fetal Nuchal fold Thickness US

0.00

0.0

1.7

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.05

0.00

1.8

—

(3019420) Tryptase [Mass/volume] in Serum or Plasma

0.00

0.0

1.3

—

8.30

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

-0.00

0.0

1.7

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

2.0

—

37.80

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

-0.00

0.0

1.0

—

(3019145) Choriogonadotropin.beta subunit free [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.9

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

0.00

-0.00

0.0

1.2

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

-0.00

0.0

1.0

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

-0.00

0.0

1.6

—

(3023511) Choriogonadotropin [Units/volume] in Urine

0.00

-0.00

0.0

1.0

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

(3017315) Amylase [Enzymatic activity/volume] in Urine

0.00

-0.00

0.0

1.0

—

2304.00

—

(3005570) Glucose [Moles/volume] in Urine

0.00

-0.00

0.0

2.4

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

(40768806) Pleura Pathology biopsy report

0.00

-0.00

0.0

1.6

—

(40768800) Prostate Pathology biopsy report

0.00

-0.00

0.0

1.4

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

-0.00

0.0

1.6

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

0.00

-0.00

0.0

3.2

—

(3011985) Renin [Units/volume] in Plasma

0.00

-0.00

0.0

1.0

—

15.54

—

(3010838) Calcium [Moles/time] in 24 hour Urine

0.00

-0.00

0.0

1.6

—

5.57

—

(3027315) Oxygen [Partial pressure] in Blood

0.00

-0.00

0.0

7.6

—

7.80

—

(3037756) Immunofixation for Serum or Plasma

0.00

-0.00

0.0

1.4

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

-0.00

0.0

1.6

—

(3024172) Erythropoietin (EPO) [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

13.12

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.2

—

43.40

—

(3042111) Morphology [Interpretation] in Bone marrow Narrative

0.00

-0.00

0.0

1.0

—

(3001788) Aldosterone [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

227.40

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

0.00

-0.00

0.0

1.4

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

0.00

-0.00

0.0

1.4

—

(42529406) Shigella sp [Presence] in Stool by Culture

0.00

-0.00

0.0

1.4

—

(40763324) Parainfluenza virus 1 RNA [Presence] in Isolate by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(40763470) Parainfluenza virus 4 RNA [Presence] in Isolate by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

-0.00

0.0

1.6

—

(3010421) pH of Blood

0.00

-0.00

0.0

7.8

—

7.42

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(1616796) Gas panel - Central venous blood

0.00

-0.00

0.0

6.8

—

(3013290) Carbon dioxide [Partial pressure] in Blood

0.00

-0.00

0.0

7.6

—

5.04

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.8

—

Mortality – FinRegistry

↥

Association

Association between endpoint G6_DISOLF and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have G6_DISOLF.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: G6_DISOLF – Disorders of olfactory nerve

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Disorders of olfactory nerve

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints